CN113116718B - Acupuncture point needle embedding composite device for preventing and treating vomiting and packing plate thereof - Google Patents

Acupuncture point needle embedding composite device for preventing and treating vomiting and packing plate thereof Download PDF

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Publication number
CN113116718B
CN113116718B CN202110325414.1A CN202110325414A CN113116718B CN 113116718 B CN113116718 B CN 113116718B CN 202110325414 A CN202110325414 A CN 202110325414A CN 113116718 B CN113116718 B CN 113116718B
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needle
substrate
thermal expansion
expansion block
preventing
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CN113116718A (en
Inventor
文凤
梁春
贺治青
丁茹
岳小强
王蓓
孟庆翔
王燕
冯欣伟
周冰华
王晓炜
任昌振
汪展辉
牛文豪
顾宁越
陈雅莎
陈一泓
陈慧
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Shanghai Changzheng Hospital
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Shanghai Changzheng Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A61H39/08Devices for applying needles to such points, i.e. for acupuncture ; Acupuncture needles or accessories therefor
    • A61H39/086Acupuncture needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rehabilitation Therapy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Finger-Pressure Massage (AREA)

Abstract

The invention relates to a composite device for embedding needles in acupuncture points for preventing and treating vomit, which comprises a thumb-tack needle body consisting of a needle head and a substrate, wherein the needle head is a hollow needle, a medicine carrying cavity communicated with the hollow needle is arranged in the substrate, and a thermal expansion block is fixed beside the medicine carrying cavity; the thermal expansion block and the medicine carrying cavity are separated by an isolating film. The invention has the advantages that the transient local stimulation of the needle pressing is converted into long-term cooperation with the medicine, the long-term effective control and improvement on the vomit symptom can be realized, and the utilization rate of medical data is improved.

Description

Acupuncture point needle embedding composite device for preventing and treating vomiting and packing plate thereof
Technical Field
The invention relates to medical equipment, in particular to an improved thumb-tack needle for vomit intervention.
Background
At present, the medicine intervention is mainly adopted clinically aiming at the vomiting, for example, diphenhydramine is used aiming at the vomiting caused by carsickness and seasickness, and a highly selective 5-hydroxytryptamine (5-HT 3) receptor antagonist such as ondansetron is adopted aiming at the vomiting caused by chemotherapy medicines of tumor patients, but the medicines have a plurality of problems, for example, the problems of large side effect, high cost, difficult control of action time and the like, and an intervention means which can be used in a short time, has definite curative effect and low cost and can be used by simple training is urgently needed clinically; in addition, there are attempts to intervene in emesis by using acupuncture or needle pressing in the prior art, but some patients only have short-term curative effects, the treatment efficacy time is kept short, the clinical practical requirements of relieving and controlling emesis episodes for a long time cannot be realized, and repeated implementation is needed, which increases the workload of doctors on one hand and also causes the comfort of patients to be obviously reduced on the other hand.
The common thumb-tack needles in the market of China at present are mainly from Japan, and are mainly punched into the dermis layer of the skin through metal needles, the diameter of each metal needle is small, the length of each needle is 0.3mm to 1.5mm, the irritation to the human body is easy to accept, and the thumb-tack needles are pasted on the skin to fix acupuncture points to play a role. The base part of the thumb-tack needle is fixed on the plastic base in a round or square way for increasing the stress area and being convenient to implement, and the back part of the thumb-tack needle is coated with viscous materials to be conveniently fixed on the local part of the acupuncture point. However, the above-mentioned pressing needles mostly use the electrochemical or physical stimulation of the metal needle tips to activate the corresponding acupuncture points to play the role of dredging and activating the channels and collaterals. There is also patent disclosure (patent CN 202010504328.2) that spontaneous heating material is used to generate heat at the base, but there are a series of problems such as the thickness of the exothermic material is difficult to control and the duration is not long enough, so that the therapy advantage of the small volume of the thumb-tack needle is lost in order to add the bulky exothermic material.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and solve the problem of poor treatment effect of a single pressing needle.
In order to achieve the aim, the invention provides an acupoint needle burying composite device for preventing and treating vomit, which comprises a needle pressing body consisting of a needle head and a substrate, wherein the needle head is a hollow needle, a medicine carrying cavity communicated with the hollow needle is arranged in the substrate, and a thermal expansion block is fixed beside the medicine carrying cavity; the thermal expansion block and the medicine carrying cavity are separated by an isolating film.
The back surface of the substrate is provided with needles and is lined with an adhesive layer for fixing skin, and the front surface of the substrate is the surface without needles.
After the thermal expansion block is fixed by the pressing needle, the volume of the medicine carrying cavity is extruded by the heating of the human body, and the pre-stored medicine in the medicine carrying cavity is output through the hollow needle. In order to prevent vomiting, the related medicines can be selected from aromatic resuscitation-inducing traditional Chinese medicines, such as musk, salvia miltiorrhiza, borneol and the like, in order to maintain the long-term medicine effect, the subsequent medicine carrying cavity can also contain extract or concentrated extract of ginseng nourishing medicines, and related energy support is provided for the stable operation of the internal circulation of the human body after the resuscitation and the dredging of the channels and collaterals.
Preferably, the substrate is further attached with an infrared reflecting layer for reflecting human body heat on the front surface.
The specific material of the infrared reflecting layer is conventional technology in the field, and can be in the form of silver plating, aluminum plating and the like.
Preferably, the thermal expansion block is a solid-liquid phase change material with small volume change during phase change.
The solid-liquid phase change material is a conventional material in the field, such as paraffin, fatty acid, polyhydric alcohol and the like, and is firstly melted from a solid state into a liquid state and then further expanded in the heat absorption process.
Preferably, the thermal expansion block is fixed on one side of the medicine carrying cavity facing the front face of the substrate.
Preferably, the front surface of the substrate is provided with mastoid-shaped protrusions, and the thermal expansion block is accommodated in the mastoid-shaped protrusions.
Preferably, the drug-loading cavity is in a circular truncated cone shape, the small end of the circular truncated cone shape is communicated with the hollow needle, and the large end of the circular truncated cone shape is attached and abutted to the thermal expansion block.
Preferably, the passage of the hollow needle is a capillary tube with the diameter equal to 0.3 mm; the isolating membrane between the thermal expansion block and the drug loading cavity is divided into a permeable polymer membrane.
The capillary tube referred to herein will be able to perform a capillary siphon function. The permeable polymeric membrane herein can selectively allow water molecules to pass through.
Preferably, the number of the needles is three, and the needles are arranged in a triangular shape in the center of the back of the substrate.
The needle referred to herein is fixed perpendicularly to the substrate.
After the thermal expansion block expands, the medicine carrying cavity is extruded, and then the medicine liquid in the medicine carrying cavity is extruded to downwards enter subcutaneous tissues through a passage of the hollow needle, so that the prevention and treatment effects are exerted. Through the inertia isolation of the isolating membrane, the chemical or physical reaction between the thermal expansion block and the medicament in the medicament carrying cavity can be avoided.
The infrared reflecting layer reflects heat emitted by the skin back, and a part of the heat is gathered on the thermal expansion block, so that the expansion of the thermal expansion block is accelerated; the other part is reflected back to subcutaneous tissue, which can promote local blood circulation and drug absorption.
The thermal expansion block adopting the solid-liquid phase change material can avoid the large volume change when the front section absorbs heat, and the volume can be rapidly expanded when the further rear section absorbs heat. On the other hand, the solid thermal expansion block can also avoid great influence on the medicine carrying cavity when the thumb-tack needle is pressed. And the liquid thermal expansion block applies pressure uniformly to the outside, so that the isolation membrane is not easy to be damaged.
The special arrangement of the part meeting the thermal expansion block can avoid blocking the hollow needle after expansion.
The provision of the mastoid-like projection provides some indication to the user to facilitate alignment of the needle.
The round platform shape of the medicine carrying cavity is matched with the mastoid thermal expansion block (namely, the section is circular), so that the useless space in the medicine carrying cavity during extrusion can be reduced.
After the pressing needle enters subcutaneous tissue, interstitial fluid is led into the drug carrying cavity outwards due to the siphoning effect of the capillary pipeline, so that the drug is accelerated to be led out. After water molecules penetrate through the polymer film, water enters the space where the thermal expansion block is located, and therefore the volume expansion of the thermal expansion block is accelerated.
The position of article word overall arrangement has enlarged the press needle effect on the one hand to the syringe needle, avoids traditional press needle single stimulation point not enough and the amazing position deviation of acupuncture point, also can compare the single stimulation point before through forming an effect plane simultaneously and realize comparatively stable acupuncture point amazing, further cooperates the hollow design of press needle, increases the dose of advancing simultaneously to realize high-efficient the dosing.
Still provide a packing plate for preventing and treating acupuncture point of vomiting and bury needle set composite, include the acupuncture point of preventing and treating vomiting bury needle set composite, take the plate body of pit, the substrate edge of the acupuncture point of preventing and treating vomiting bury needle set composite is connected to through the structure of bursting absolutely of real, hole alternation the hole inner edge mouth of pit.
The failure structure will break the solid areas therein when subjected to shear pressure (e.g., pressing the substrate against the panel), thereby creating cracks along the failure structure when desired. The specific breaking structure can be a breakable joint, namely one or more connecting bridges are arranged on each side of the periphery of the substrate; the connecting plate can also be in the form of a tear line, namely, the connection with the peripheral plate body can be easily broken through mechanical or laser drilling technology. The needle is directed into the recess.
Preferably, the uppermost layer of the front surface of the substrate is attached with a patch with a raised edge, and the patch covers and is larger than the front surface of the substrate.
The tilting means that one corner or the raised position of the edge of the patch is folded towards the direction far away from the substrate, so that a needle applier can hold the patch conveniently to lift the patch, and the press needle can be taken out of the plate body. The patch may be provided in the form of a double-sided non-adhesive.
Through the arrangement of the breaking structure, the thumb press needle can be effectively separated from the plate body; and simultaneously provides certain strength rigidity for the connection of the two when the two are not subjected to external force.
Through the setting of paster, can cover the disconnected structure of bursting to block that impurity pollutes the syringe needle through the disconnected structure of bursting.
The invention has the advantages that the transient local stimulation of the needle pressing is converted into long-term cooperation with the medicine, the long-term effective control and improvement on the vomit symptom can be realized, and the utilization rate of medical data is improved.
Drawings
FIG. 1 is a schematic sectional view of the compound device for acupuncture point burying without needle application;
FIG. 2 is a schematic cross-sectional view of the compound device for point burial according to the present invention after needle application;
FIG. 3 is a side view of the wrapper of the present invention;
FIG. 4 is a back partial view of the packing sheet of the present invention;
FIG. 5 is a schematic view of the opening process of the packing plate of the present invention;
wherein:
1-a needle head; 2-a substrate; 21-a drug-carrying cavity;
22-a barrier film; 23-mastoid process; 3-expansion by heat;
4-an infrared reflecting layer; 5, a plate body; 51-pits;
6-breaking structure; 7-Patch.
Detailed Description
The invention is further described below with reference to the following figures and specific examples.
The acupuncture point needle embedding compound device for preventing and treating vomit shown in fig. 1-2 comprises a needle pressing body consisting of a needle head 1 and a substrate 2, wherein the needle head 1 is a hollow needle, a medicine carrying cavity 21 communicated with the hollow needle is arranged in the substrate 2, and a thermal expansion block 3 is fixed beside the medicine carrying cavity 21; the thermal expansion block 3 and the medicine carrying cavity 21 are separated by an isolation film 22 in the form of a permeable polymer film.
The back of the substrate 2 is provided with the needle head 1 and is lined with an adhesive layer for fixing the skin, and the front of the substrate 2 is the side without the needle head. The front surface of the substrate 2 is also attached with a silvered infrared reflecting layer 4 for reflecting human body heat.
The thermal expansion block 3 is a paraffin wax type solid-liquid phase change material with small volume change during phase change. The thermal expansion block 3 is fixed on one side of the medicine carrying cavity 21 facing the front surface of the substrate. The front surface of the substrate 2 is provided with mastoid-shaped protrusions 23, and the thermal expansion block 3 is accommodated in the mastoid-shaped protrusions 23. The drug-loading cavity 21 is in a circular truncated cone shape, the small end of the circular truncated cone shape is communicated with the hollow needle, and the large end of the circular truncated cone shape is attached and propped against the thermal expansion block 3.
The passage of the hollow needle is a capillary pipeline with the diameter equal to 0.3 mm. The quantity of the pinheads 1 is three, the pinheads 1 are arranged in a shape like a Chinese character 'pin' in the center of the back of the substrate 2, and the pinheads 1 are vertically fixed on the substrate 2.
The operation principle of this embodiment will be explained more specifically: the mastoid 23 contains solid-liquid phase-change material, which is separated from the drug-carrying cavity 21 corresponding to the tail end of each hollow needle in the substrate 2 by a water-permeable separation membrane 22. The drug-loading cavity 21 is separated from the thermal expansion block 3 by an isolating film 22 and is communicated with a capillary pipeline in the hollow needle. When the thumb needle is applied to a human body, the infrared reflecting layer 4 on the upper part of the mastoid-shaped protrusion 23 reflects heat dissipated by the skin, a part of the heat is gathered in the mastoid-shaped protrusion 23 and is heated to be expanded when meeting heat, meanwhile, after the thumb needle enters subcutaneous tissues, because the diameter of a capillary pipeline is small, interstitial fluid is upwards introduced into the drug carrying cavity 21 through the siphonage effect, and further enters the space where the phase change material is located through the isolation film 22, the volume expansion of the phase change material is accelerated, and because the mastoid-shaped protrusion 23 at the rear end of the expansion part pushes the isolation film 22 downwards to move, so that the drug liquid contained in the drug carrying cavity 21 is extruded to downwards and enters the subcutaneous tissues through the capillary in the hollow needle, and the pre-placing and treating effects are exerted.
In use, the front end of the hollow needle of the pressing needle can be inserted into the prefabricated concentrated and purified ointment to carry medicine in advance, and then the hollow needle penetrates into a human body, on one hand, the electrochemical action of the metal needle head can be utilized to stimulate acupuncture points, and on the other hand, the purified ointment brought by the hollow needle can break through the physical barrier of the epidermis to act on subcutaneous tissues (the medicine can be carried in advance, namely, no medicine is inserted into the hollow needle into the skin).
Along with the absorption of related medicines, liquid between subcutaneous tissues upwards moistens the medicine carrying cavity 21 along the hollow needle through the capillary siphoning effect, meanwhile, the infrared reflecting layer 4 at the top reflects one part of heat generated by local skin back to the subcutaneous tissues to promote local blood circulation and medicine absorption, the other part is continuously accumulated on the action part to trigger the phase change substance contained in the pressing needle substrate 2 to generate phase change and volume expansion, and the long-acting medicines in the medicine carrying cavity 21 are pushed downwards to enter the subcutaneous tissues through the hollow needle to continuously play related roles.
In order to prevent emesis, the related medicines can be selected from aromatic resuscitation inducing traditional Chinese medicines such as Moschus, saviae Miltiorrhizae radix, borneolum, etc., in order to maintain long-term medicinal effects, the second half of the medicine carrying cavity 21 can be provided with extract or concentrated extract containing Ginseng nourishing medicines, so as to provide related energy support for stable operation of human body internal circulation after inducing resuscitation and dredging channels and collaterals.
The packaging plate of the combined acupuncture point-burial needle device for preventing and treating vomiting shown in fig. 3 to 5 comprises the combined acupuncture point-burial needle device for preventing and treating vomiting and a plate body 5 with a pit 51, wherein the edge of a substrate 2 of the combined acupuncture point-burial needle device for preventing and treating vomiting is connected to the inner edge of the hole of the pit 51 through a solid-hole alternate breaking structure 6. The structure 6 will break solid areas therein when subjected to shear pressure (e.g., pressing the substrate 2 against the plate 5), thereby creating cracks along the structure 6 when desired. The specific bursting structure 6 adopts an easy-tearing line form, namely, the connection with the peripheral plate body 5 is realized through a laser drilling technology. The needle 1 is directed into the recess 51. The uppermost layer of the front surface of the substrate 2 is attached with a patch 7 with a raised edge, and the patch 7 covers and is larger than the front surface of the substrate 2.
The operation principle of the packaging board of this embodiment will be explained more specifically: the concave pit 51 forms an outer protective cover for the needle head 1, an isolation space is formed between the concave pit and the plate body 5, the needle head 1 is in a clean state before being unsealed, and the easy-to-tear line between the thumb-tack needle and the square plate body 5 is discontinuously and uniformly distributed on two circles of the periphery of the substrate 2. The substrate 2 is pressed downwards to cause the easy-to-tear line to be broken, the substrate 2 is separated from the plate body 5 along the easy-to-tear line at the periphery,
as shown in fig. 5, pressing down causes the snap fastener to separate from the snap-broken structure 6 on the board body 5; the thumb-tack needle falls into the concave pit 51; the user can pick up the raised part with his or her fingers and take it out of the recess 51, so that the subsequent operation can be performed.
The effect produced by this embodiment is: the press needle is improved to load related medicines, the medicines are remained at local parts to play a continuous role after the press needle is penetrated into a dermal layer of skin to stimulate acupuncture points, and the related loaded medicines can be sequentially administered in vivo by selecting different medicine formulas according to needs. For example, initially, the absorption of the drugs is further promoted on the basis of acupuncture through the resuscitation effect of the aromatic warming and activating drugs, and on the other hand, the vomiting symptom of the patient is controlled and relieved, and as the efficacy of the drugs subsides, the overall endurance level of the patient is improved through the warming and invigorating effects of the subsequent drugs.
While the preferred embodiments of the present invention have been illustrated and described, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (7)

1. A composite device for embedding needles in acupuncture points for preventing and treating vomit comprises a needle pressing body consisting of a needle head and a substrate, and is characterized in that the needle head adopts a hollow needle, a drug carrying cavity communicated with the hollow needle is arranged in the substrate, and a thermal expansion block is fixed beside the drug carrying cavity; the thermal expansion block and the medicine carrying cavity are separated by an isolating film;
the front surface of the substrate is also attached with an infrared reflecting layer for reflecting human body heat;
the thermal expansion block is fixed on one side of the medicine carrying cavity facing the front surface of the substrate;
the front surface of the substrate is provided with mastoid-shaped protrusions, and the thermal expansion block is accommodated in the mastoid-shaped protrusions.
2. The point-embedding needle composite device for preventing and treating emesis according to claim 1, wherein the thermal expansion block is a solid-liquid phase change material with small volume change during phase change.
3. The acupuncture point needle burying composite device for preventing and treating emesis of claim 1, wherein said drug carrying cavity is in the shape of a circular truncated cone, a small end of the circular truncated cone is communicated with said hollow needle, and a large end of the circular truncated cone is attached to abut against said thermal expansion block.
4. The point-embedding needle composite device for preventing and treating emesis according to claim 1, wherein the passage of the hollow needle is a capillary channel with a diameter equal to 0.3 mm; the isolating membrane between the thermal expansion block and the drug loading cavity is divided into a permeable polymer membrane.
5. The point-point needle embedding composite device for preventing and treating emesis of claim 1, wherein the number of the needle heads is three, and the needle heads are arranged in a delta shape at the center of the back surface of the substrate.
6. A packaging board for a combined acupuncture point needle implantation device for emesis prevention and treatment, comprising the combined acupuncture point needle implantation device for emesis prevention and treatment according to any one of claims 1 to 5, and a board body with a concave pit, wherein the edge of the substrate of the combined acupuncture point needle implantation device for emesis prevention and treatment is connected to the inner edge of the hole of the concave pit through a solid-hole alternate breaking structure.
7. The packaging board of claim 6, wherein a patch with a raised edge is attached to the top of the front surface of the substrate, and the patch covers and is larger than the front surface of the substrate.
CN202110325414.1A 2021-03-26 2021-03-26 Acupuncture point needle embedding composite device for preventing and treating vomiting and packing plate thereof Active CN113116718B (en)

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EP2384781A1 (en) * 2010-05-06 2011-11-09 Immunservice GmbH Puncture needle cover with a microneedle array
CN102552022A (en) * 2012-01-16 2012-07-11 章玮 Warm needle warm moxibustion apparatus
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CN203483654U (en) * 2013-08-01 2014-03-19 中国十九冶集团有限公司职工医院 Acupuncture needle
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CN111135076A (en) * 2020-01-11 2020-05-12 任胜洪 Adjustable traditional Chinese medicine acupuncture needle
CN111529382A (en) * 2020-06-05 2020-08-14 无锡市中医医院 Painless multifunctional thumb-tack needle

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Publication number Priority date Publication date Assignee Title
KR100867721B1 (en) * 2007-09-03 2008-11-10 이홍재 Needle assembly for traditional oriental medicine
CN205084002U (en) * 2015-11-12 2016-03-16 任英民 A subsides of thumb -tack needle for subcutaneous embedding magnetism medicine carrying that is used for human yu cave and acupuncture point on ears
CN208574012U (en) * 2018-02-01 2019-03-05 屠家凯 A kind of thumb-tack needle for subcutaneous embedding ear shape packaging structure

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101076409A (en) * 2004-11-18 2007-11-21 3M创新有限公司 Method of contact coating a microneedle array
KR100602556B1 (en) * 2005-05-04 2006-07-25 정하철 Needle for chinese medicine
EP2384781A1 (en) * 2010-05-06 2011-11-09 Immunservice GmbH Puncture needle cover with a microneedle array
CN102552022A (en) * 2012-01-16 2012-07-11 章玮 Warm needle warm moxibustion apparatus
CN202950931U (en) * 2012-12-03 2013-05-29 上海市浦东新区中医医院 Drawing pin type warming acupuncture device
CN203483654U (en) * 2013-08-01 2014-03-19 中国十九冶集团有限公司职工医院 Acupuncture needle
CN106214478A (en) * 2016-08-16 2016-12-14 刘海燕 A kind of Traditional Chinese medicine acupuncture needle
CN209137345U (en) * 2018-05-30 2019-07-23 周玉 Based on the thumb-tack needle for subcutaneous embedding device for opening cave
CN111135076A (en) * 2020-01-11 2020-05-12 任胜洪 Adjustable traditional Chinese medicine acupuncture needle
CN111529382A (en) * 2020-06-05 2020-08-14 无锡市中医医院 Painless multifunctional thumb-tack needle

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