CN112933203A - 一种抗疲劳改善性功能药酒的中药组合物及其制备方法 - Google Patents

一种抗疲劳改善性功能药酒的中药组合物及其制备方法 Download PDF

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CN112933203A
CN112933203A CN202011351341.5A CN202011351341A CN112933203A CN 112933203 A CN112933203 A CN 112933203A CN 202011351341 A CN202011351341 A CN 202011351341A CN 112933203 A CN112933203 A CN 112933203A
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parts
traditional chinese
chinese medicine
medicine composition
wine
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刘显均
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Sichuan Yehum Health Pharmacy Co ltd
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Sichuan Yehum Health Pharmacy Co ltd
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Abstract

本发明公开了一种抗疲劳改善性功能药酒的中药组合物及其制备方法，属于保健滋补药酒，特别是以肉苁蓉提取浓缩物为主要功能原料配制而成的保健滋补酒。制备其活性成分原料包括肉苁蓉、熟地、刺五加、韭菜籽、无名子、五味子、诃子、补骨脂、南天竹子、分心木、淫羊藿、丁香、附片、升麻、干姜、花椒、人参、山茱萸、黄芪、黄精、灵芝、天麻、山药、茯苓、松茸、枸杞子、桑葚、益智仁、陈皮、蛹虫草、玛咖粉、白茅根、甘草、冰糖、纯粮白酒。本发明的优点是制备活性成分控制准确，原料配伍合理科学，配制成品酒液简便，成品的色泽偏差小，便于规模化生产。本品具有抗疲劳、改善性功能的保健功能。

Description

一种抗疲劳改善性功能药酒的中药组合物及其制备方法
技术领域
本发明涉及保健酒领域，具体涉及一种抗疲劳改善性功能药酒的中药组合物及其制备方法。
背景技术
数千年来，祖国医学在药酒方面积累了宝贵的经验，有着丰富的内容。药酒的滋补养生作用，很早就被人们知晓，但是，传统药酒以单味或多味药材浸泡于酒中而成，属配制酒类。而这类酒皆是饮用人根据自己的喜好而随意配制的，原料配伍缺乏科学性，很难起到养生保健的作用，满足不了人们对养生保健酒的需要。我国传统的中医学治疗改善阳痿具有悠久的历史。中医认为，中青年时期的阳痿以痰热血瘀肝郁为主，肾虚次之。老年时期的阳痿以肾虚血瘀为主，而肝郁痰热次之。阳痿的中医基本病理变化是肝郁肾虚湿热血瘀。但是，对于阳痿的治疗应该秉承先辨病后辨证，辨病与辨证论治相结合的原则，证从病辨，以病统证，只有将辨病论治与辨证论治有机地结合在一起，才能提高治疗效果。只辨证不辨病，则很难把握其病的全貌，从而治疗也往往难以取得好效。因此，需要对引起阳痿的原因或机理进行细化，并针对病因和病理采用相应的药物来进行纠正和治疗，从而获得更加的治疗效果。
发明内容
针对现有技术的不足，本发明提供了一种治疗改善阳痿具有抗疲劳改善性功能药酒的中药组合物及其制备方法，本发明的中药组合物具有添精、生精作用，不仅对痰热肝郁型和肾虚血瘀型阳痿有显著的疗效，而且对肾虚所致腰膝酸软、头晕耳鸣、神疲乏力、遗精早泄、夜尿频数、记忆力减退等症状有明显改善作用，且疗效显著、毒副作用小。另外，本发明中药组合物的制备方法原料易得、步骤简单、重复性好。
为实现本申请的目的，本发明是通过下述的技术方案来实现的。
一种抗疲劳改善性功能药酒的中药组合物，由以下重量份配比的中药制成：
肉苁蓉15-25份、熟地15-25份、刺五加10-15份、韭菜籽5-8份、无名子5-8份、五味子15-20份、诃子5-10份、补骨脂10-15份、南天竹子 5-8份、分心木5-10份、淫羊藿15-25份、丁香5-7份、附片3-6份、升麻 3-6份、干姜5-10份、花椒3-6份、人参8-15份、山茱萸15-25份、黄芪 5-15份、黄精15-25份、灵芝5-15份、天麻5-10份、山药15-25份、茯苓 15-25份、松茸5-10份、枸杞子15-25份、桑葚15-25份、益智仁15-25份、陈皮5-10份、蛹虫草5-10份、玛咖粉5-10份、白茅根15-25份、甘草15-25 份、冰糖5-10份。
本发明还提供了一种抗疲劳改善性功能药酒的中药组合物制备成保健酒的方法包括以下步骤：
(1)将肉苁蓉、熟地、刺五加、韭菜籽、无名子、五味子、诃子、补骨脂、南天竹子、分心木、淫羊藿、丁香、附片、升麻、干姜、花椒、人参、山茱萸、黄芪、黄精、灵芝、天麻、山药、茯苓、松茸、枸杞子、桑葚、益智仁、陈皮、蛹虫草、玛咖粉、白茅根、甘草，按要求挑选清洗烘干混合粉碎成粗粉，加2-10倍体积的水煎煮两次，第一次2-5小时，第二次1-4小时，合并煎液并保留滤渣，过滤煎液，滤液60℃减压浓缩至相对密度为1.12-1.18的清膏备用；
(2)将步骤(1)的滤渣加2-10倍体积的50-80％乙醇，回流提取2 次，每次1-4小时，过滤，合并滤液，然后减压蒸馏除去乙醇，并60℃浓缩至相对密度为1.12-1.18的清膏备用；
(3)将步骤(1)和步骤(2)的清膏加热至50-80℃趁热过200-400 目筛滤过，滤液进行喷雾干燥，即得喷干粉，过100-200目筛混合均匀，即得细粉备用；
(4)将冰糖5-10熬化备用；
(5)用纯化水将计算剂量的规定酒精度的酒液加入陈化酒罐中备用；
(6)将步骤(3)的细粉、步骤(4)的冰糖和步骤(5)的陈化酒混合、搅拌、静置陈化、过滤装瓶即可。
本发明在我国传统中医学基础上，科学合理配方，共奏滋阴补肾、疏通肝气、补益气血的功效，不仅对痰热肝郁型和肾虚血瘀型阳痿有显著的疗效，而且对肾虚所致腰膝酸软、头晕耳鸣、神疲乏力、遗精早泄、夜尿频数、记忆力减退等症状有明显改善作用。本方经临床应用并跟踪随访均未见明显不良反应及副作用，且疗效稳定。
本发明的中药组合物经水煎煮提取后，有效成分含量更高，并且可进一步制备成汤剂、丸剂、片剂、胶囊剂、颗粒剂、口服液等患者更易于接受的形式，为后期发展产品预留了广阔的空间。渗漉提取部分中药材原料，更好地保留了中药材原料色香味，使成品酒体口感更饱满，饮用更愉悦。用于制备本发明中药制剂的方法原料易得、步骤简单、重复性好，满足了工业生产的需要。
本方中肉苁蓉补肾阳,益精血,润肠通便,用于:阳痿,***,腰膝酸软,筋骨无力。具有统率全局的作用，是为君药。熟地补血养阴，填精益髓；刺五加促***，抗疲劳，针对脾肾阳虚、腰膝酸软，困倦乏力；人参大补元气，复脉固脱、补脾益肺、安神益智，与刺五加、熟地同居臣位。韭菜籽温补肝肾、壮阳固精、强筋壮骨，无名子温肾暖脾，五味子收敛固涩,益气生津,补肾，诃子益肺治尿频遗精，补骨脂补肾助阳、固精缩尿、温脾止泻，南天竹子清肝明目、敛肺平喘，分心木涩精缩尿，淫羊藿补肾壮阳，祛风除湿，丁香温中降逆、行气止痛、温肾壮阳，附片温补脾肾、散寒止痛、回阳救逆、温阳逐寒，升麻升阳举陷，干姜温中散寒、回阳通脉、温肺化饮，花椒温中行气，山茱萸消炎抗菌、降血糖、益肾固精，黄芪补气固表，黄精补气养阴，健脾，润肺，益肾，灵芝养心安神,养肺益气,理气化淤、滋肝健脾。主治虚劳体弱,神疲乏，天麻息风止痉，平抑肝阳，祛风通络，枸杞子滋补肝肾，益精明目，桑葚滋阴补血、补肝益肾、生津止渴，益智仁温脾止泻摄涎，暖肾缩尿固精，蛹虫草治肾虚、阳萎遗精、腰膝酸痛，玛咖粉抗疲劳、增强体力、增加***质量，增加***活力的作用。在臣药的带领基础上，共同辅助君药的补肾壮阳，增添臣药益气抗疲劳之功力，合并组成佐药，拱护君臣药力。山药补脾生津，茯苓健脾养胃，松茸保肝护肝，促进胃肠消化，增香调味，陈皮理气和中，甘草调和诸药，使君臣佐药温而不燥，达到壮阳而不燥，滋阴而不腻之功，同为使药。以上诸药君臣佐使，各施其职，使其达到壮阳抗疲劳，改善性功能之功效。
为了证明本发明产品的抗疲劳改善性功能药酒作用，对100例受试人作了***的观察：
受试人群：男性，年龄在35-70岁之间，无心血管、肝、肾、糖尿病等严重原发性疾病。
受试方案：饮用本发明产品酒，每日早晚各一次，每次饮用量35-50ml。
时间：90天。
有效标准：神疲乏力感消除，精力充沛有活力，食欲增强，思维活跃，睡眠好，心情舒畅，体质明显增强，身体对外界刺激(冷热)抵抗能力增强，性生活疲劳时间延后。
经统计观察期间符合上述有效标准的98人，有效率达到98％。在饮用过程中未发现有不良反应，饮用安全。
具体实施方式
实施例1
本实施例提供了一种抗疲劳改善性功能的药酒中药组合物；按照下述配比称取原料(kg)：
肉苁蓉20、熟地20、刺五加12、韭菜籽6、无名子7、五味子17、诃子8、补骨脂12、南天竹子7、分心木7、淫羊藿20、丁香6、附片4、升麻4、干姜7、花椒4、人参10、山茱萸20、黄芪10、黄精20、灵芝10、天麻7、山药20、茯苓20、松茸7、枸杞子20、桑葚20、益智仁20、陈皮7、蛹虫草8、玛咖粉8、白茅根20、甘草20。
制备方法：
(1)称取肉苁蓉、熟地、刺五加、韭菜籽、无名子、五味子、诃子、补骨脂、南天竹子、分心木、淫羊藿、丁香、附片、升麻、干姜、花椒、人参、山茱萸、黄芪、黄精、灵芝、天麻、山药、茯苓、松茸、枸杞子、桑葚、益智仁、陈皮、蛹虫草、玛咖粉、白茅根、甘草，按要求挑选清洗烘干混合粉碎成粗粉，加2-10倍体积的水煎煮两次，第一次加8倍量的纯化水煎煮5小时，第二次加6倍量的纯化水煎煮4小时，合并煎液并保留滤渣，过滤煎液，滤液60℃减压浓缩至相对密度为1.12-1.18的清膏备用；
(2)将步骤(1)的滤渣加8倍体积的60％乙醇，回流提取2次，每次2 小时，过滤，合并滤液，然后减压蒸馏除去乙醇，并60℃浓缩至相对密度为1.12-1.18的清膏备用；
(3)将步骤(1)和步骤(2)的清膏加热至80℃趁热过200-400目筛滤过，滤液进行喷雾干燥，即得喷干粉，过150目筛混合均匀，即得细粉备用；
(4)将冰糖熬化备用；
(5)用纯化水将计算剂量的规定酒精度的酒液加入陈化酒罐中备用；
(6)将(3)(4)(5)混合，搅拌、静置陈化15天、过滤装瓶即可。
实施例2
本实施例提供了一种抗疲劳改善性功能的药酒中药组合物；按照下述配比称取原料(kg)：
肉苁蓉16、熟地15、刺五加10、韭菜籽5、无名子5、五味子15、诃子6、补骨脂10、南天竹子5、分心木6、淫羊藿15、丁香5、附片3、升麻3、干姜5、花椒3、人参8、山茱萸15、黄芪7、黄精15、灵芝6、天麻6、山药15、茯苓15、松茸5、枸杞子15、桑葚16、益智仁16、陈皮6、蛹虫草6、玛咖粉6、白茅根16、甘草15。
制备方法：
(1)称取肉苁蓉、熟地、刺五加、韭菜籽、无名子、五味子、诃子、补骨脂、南天竹子、分心木、淫羊藿、丁香、附片、升麻、干姜、花椒、人参、山茱萸、黄芪、黄精、灵芝、天麻、山药、茯苓、松茸、枸杞子、桑葚、益智仁、陈皮、蛹虫草、玛咖粉、白茅根、甘草，按要求挑选清洗烘干混合粉碎成粗粉，加2-10倍体积的水煎煮两次，第一次加9倍量的纯化水煎煮5小时，第二次加5倍量的纯化水煎煮4小时，合并煎液并保留滤渣，过滤煎液，滤液60℃减压浓缩至相对密度为1.12-1.18的清膏备用；
(2)将步骤(1)的滤渣加8倍体积的70％乙醇，回流提取2次，每次2 小时，过滤，合并滤液，然后减压蒸馏除去乙醇，并60℃浓缩至相对密度为1.12-1.18的清膏备用；
(3)将步骤(1)和步骤(2)的清膏加热至80℃趁热过200目筛滤过，滤液进行喷雾干燥，即得喷干粉，然后加入步骤(2)的细粉，过150目筛混合均匀，即得细粉备用；
(4)将冰糖熬化备用；
(5)用纯化水将计算剂量的规定酒精度的酒液加入陈化酒罐中备用；
(6)将(3)(4)(5)混合，搅拌、静置陈化20天、过滤装瓶即可。
实施例3
本实施例提供了一种抗疲劳改善性功能的药酒中药组合物；按照下述配比称取原料(kg)：
肉苁蓉25、熟地25、刺五加15、韭菜籽8、无名子5、五味子18、诃子8、补骨脂15、南天竹子8、分心木10、淫羊藿24、丁香7、附片5、升麻5、干姜10、花椒5、人参15、山茱萸23、黄芪15、黄精24、灵芝 13、天麻10、山药23、茯苓25、松茸10、枸杞子25、桑葚23、益智仁 25、陈皮10、蛹虫草10、玛咖粉6、白茅根16、甘草15。
制备方法：
(1)称取肉苁蓉、熟地、刺五加、韭菜籽、无名子、五味子、诃子、补骨脂、南天竹子、分心木、淫羊藿、丁香、附片、升麻、干姜、花椒、人参、山茱萸、黄芪、黄精、灵芝、天麻、山药、茯苓、松茸、枸杞子、桑葚、益智仁、陈皮、蛹虫草、玛咖粉、白茅根、甘草，按要求挑选清洗烘干混合粉碎成粗粉，加2-10倍体积的水煎煮两次，第一次加10倍量纯化水煎煮5小时，第二次加5倍量纯化水煎煮3小时，合并煎液并保留滤渣，过滤煎液，滤液60℃减压浓缩至相对密度为1.12-1.18的清膏备用；
(2)将步骤(1)的滤渣加7倍体积的80％乙醇，回流提取2次，每次3 小时，过滤，合并滤液，然后减压蒸馏除去乙醇，并60℃浓缩至相对密度为1.12-1.18的清膏备用；
(3)将步骤(1)和步骤(2)的清膏加热至50℃趁热过400目筛滤过，滤液进行喷雾干燥，即得喷干粉，过200目筛混合均匀，即得细粉备用；
(4)将冰糖熬化备用；
(5)用纯化水将计算剂量的规定酒精度的酒液加入陈化酒罐中备用；
(6)将(3)(4)(5)混合，搅拌、静置陈化30天、取上清液过滤装瓶即可。
以上所述仅是本发明优选的实施方式，但本发明的保护范围并不局限于此，任何基于本发明所提供的技术方案和发明构思进行的改造和替换都应涵盖在本发明的保护范围内。

Claims (2)

1.一种抗疲劳改善性功能药酒的中药组合物，其特征在于由以下重量份配比的中药制成：
肉苁蓉15-25份、熟地15-25份、刺五加10-15份、韭菜籽5-8份、无名子5-8份、五味子15-20份、诃子5-10份、补骨脂10-15份、南天竹子5-8份、分心木5-10份、淫羊藿15-25份、丁香5-7份、附片3-6份、升麻3-6份、干姜5-10份、花椒3-6份、人参8-15份、山茱萸15-25份、黄芪5-15份、黄精15-25份、灵芝5-15份、天麻5-10份、山药15-25份、茯苓15-25份、松茸5-10份、枸杞子15-25份、桑葚15-25份、益智仁15-25份、陈皮5-10份、蛹虫草5-10份、玛咖粉5-10份、白茅根15-25份、甘草15-25份、冰糖5-10份。
2.如权利要求1所述的一种抗疲劳改善性功能药酒的中药组合物制备成保健酒的方法，其特征在于包括以下步骤：
(1)将肉苁蓉、熟地、刺五加、韭菜籽、无名子、五味子、诃子、补骨脂、南天竹子、分心木、淫羊藿、丁香、附片、升麻、干姜、花椒、人参、山茱萸、黄芪、黄精、灵芝、天麻、山药、茯苓、松茸、枸杞子、桑葚、益智仁、陈皮、蛹虫草、玛咖粉、白茅根、甘草，按要求挑选清洗烘干混合粉碎成粗粉，加2-10倍体积的水煎煮两次，第一次2-5小时，第二次1-4小时，合并煎液并保留滤渣，过滤煎液，滤液60℃减压浓缩至相对密度为1.12-1.18的清膏备用；
(2)将步骤(1)的滤渣加2-10倍体积的50-80％乙醇，回流提取2次，每次1-4小时，过滤，合并滤液，然后减压蒸馏除去乙醇，并60℃浓缩至相对密度为1.12-1.18的清膏备用；
(3)将步骤(1)和步骤(2)的清膏加热至50-80℃趁热过200-400目筛滤过，滤液进行喷雾干燥，即得喷干粉，过100-200目筛混合均匀，即得细粉备用；
(4)将冰糖5-10熬化备用；
(5)用纯化水将计算剂量的规定酒精度的酒液加入陈化酒罐中备用；
(6)将步骤(3)的细粉、步骤(4)的冰糖和步骤(5)的陈化酒混合、搅拌、静置陈化、过滤装瓶即可。
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CN114698841A (zh) * 2022-04-26 2022-07-05 广州腾麟生物科技有限公司 一种促进血液循环改善亚健康的本草提取物

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