CN112870299A - Traditional Chinese medicine composition for assisting in reducing blood sugar and preparation method thereof - Google Patents
Traditional Chinese medicine composition for assisting in reducing blood sugar and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for assisting in reducing blood sugar and a preparation method thereof, and relates to the technical field of traditional Chinese medicine compositions, wherein the traditional Chinese medicine composition for assisting in reducing blood sugar mainly comprises the following raw materials in parts by weight: the oral liquid is prepared into an oral liquid dosage form by the processes of extraction, concentration, alcohol precipitation, centrifugation, preparation, re-centrifugation, filling, sterilization and the like, and during the preparation process, the alcohol precipitation technology is adopted to remove components such as tannic acid, protein and the like in medicinal materials to obtain a clear and transparent solution; the invention is prepared into an oral liquid preparation formulation, is convenient to take, is beneficial to the quick absorption of effective components, achieves the effect of assisting in reducing blood sugar, and can prevent complications. The process and the dosage form of the invention are scientific and reasonable, and have obvious advantages.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for assisting in reducing blood sugar and a preparation method thereof.
Background
With the rapid development of social economy, people's daily life habits and dietary structures are greatly changed, which is mainly reflected in that while the amount of exercise in modern life is gradually reduced, the proportion of unhealthy foods with high calorie, high fat and low dietary fiber in the diet is gradually increased. The transformation of bad living habits and dietary structures has led to the rapid increase of symptoms such as hyperglycemia, hyperlipidemia, hypertension, obesity, etc., wherein the increase of the incidence of diabetes mellitus, which has hyperglycemia as a main symptom, and the economic burden caused thereby are most significant.
Diabetes is a syndrome of the damage of multiple systems and multiple organs caused by the metabolic disturbance of sugar, fat and protein due to various reasons, which is characterized by the increase of blood sugar and diabetes. With the improvement of living standard and the change of life style, the number of patients with hyperglycemia and diabetes is increasing, and the disease becomes the third disease following malignant tumor and cardiovascular disease, and seriously threatens the health of human beings.
At present, the hypoglycemic market in China mainly comprises synthetic drugs, which account for about 75 percent of the whole market; however, the drug resistance, liver and kidney injury and the like are easily caused by long-term taking of the synthetic drugs. In about 25% of the natural drug markets, most of the selected natural drug formulations are not reasonable enough, and cannot fundamentally lower blood sugar and improve diabetic complications.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for assisting in reducing blood sugar and a preparation method thereof, and aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
a traditional Chinese medicine composition for assisting in reducing blood sugar mainly comprises the following raw materials in parts by weight: 8-16 parts of dendrobium officinale, 15-28 parts of bighead atractylodes rhizome, 12-16 parts of semen cuscutae, 1-3 parts of antioxidant, 2-6 parts of astragalus membranaceus, 10-20 parts of wolfberry fruit, 8-16 parts of American ginseng, 9-16 parts of purslane, 5-10 parts of rhizoma anemarrhenae and 4-9 parts of longhairy antenoron herb.
As a further scheme of the invention: the traditional Chinese medicine composition for assisting in reducing blood sugar mainly comprises the following raw materials in parts by weight: 10-14 parts of dendrobium officinale, 20-24 parts of bighead atractylodes rhizome, 13-15 parts of semen cuscutae, 2-3 parts of antioxidant, 3-5 parts of astragalus membranaceus, 12-18 parts of wolfberry fruit, 10-14 parts of American ginseng, 11-17 parts of purslane, 7-9 parts of rhizoma anemarrhenae and 5-8 parts of desmodium.
As a still further scheme of the invention: the traditional Chinese medicine composition for assisting in reducing blood sugar mainly comprises the following raw materials in parts by weight: 12 parts of dendrobium officinale, 22 parts of bighead atractylodes rhizome, 14 parts of semen cuscutae, 3 parts of antioxidant, 4 parts of astragalus membranaceus, 15 parts of wolfberry fruit, 12 parts of American ginseng, 14 parts of purslane, 8 parts of rhizoma anemarrhenae and 7 parts of desmodium.
As a still further scheme of the invention: the antioxidant is selected from one or more of sodium ascorbate, sodium benzoate, phospholipid, and potassium sorbate.
As a still further scheme of the invention: the antioxidant is sodium ascorbate.
As a still further scheme of the invention: the water is purified water.
As a still further scheme of the invention: the Chinese medicinal compound composition is orally taken.
A preparation method of a traditional Chinese medicine composition for assisting in reducing blood sugar comprises the following steps:
1) weighing 8-16 parts of dendrobium officinale, 15-28 parts of bighead atractylodes rhizome, 12-16 parts of semen cuscutae, 1-3 parts of antioxidant, 2-6 parts of astragalus membranaceus, 10-20 parts of wolfberry fruit, 8-16 parts of American ginseng, 9-16 parts of purslane, 5-10 parts of rhizoma anemarrhenae and 4-9 parts of desmodium;
2) pretreatment: pulverizing radix Panacis Quinquefolii, and sieving with 100 mesh sieve to obtain radix Panacis Quinquefolii powder; crushing the dendrobium officinale, and sieving with a 50-mesh sieve to obtain dendrobium officinale powder;
3) extracting and concentrating: decocting the American ginseng powder and the dendrobium officinale powder obtained by crushing in the step 2) and the bighead atractylodes rhizome, the dodder seed, the astragalus root, the medlar, the purslane, the rhizoma anemarrhenae and the desmodium in water, filtering, combining the filtrates, concentrating under reduced pressure at-0.09 +/-0.01 MPa and 60 +/-5 ℃ to obtain clear paste, centrifuging, and taking supernatant;
4) alcohol precipitation: adding ethanol into the supernatant obtained in the step 3), refrigerating, centrifuging, recovering ethanol in the supernatant until no alcohol smell exists in the supernatant, and filtering to obtain a solution I, wherein the step aims at removing components such as tannic acid, protein and the like in the medicinal materials to obtain a clear and transparent solution;
5) preparing liquid: adding an antioxidant into the solution I obtained in the step 4), stirring for dissolving, adding water to obtain a solution II, wherein the antioxidant can keep the functional components of the polysaccharide, the polyphenol and the total flavone from being oxidized and decomposed, so that the efficacy of the product is kept;
6) refrigerating, centrifuging and filtering: refrigerating the solution II obtained in the step 5), centrifuging and filtering to obtain filtrate, and refrigerating the precipitate at low temperature to keep the activity of the effective components;
7) and (3) sterilization: sterilizing the filtrate obtained in the step 6) at high temperature to obtain the traditional Chinese medicine composition for assisting in reducing blood sugar.
As a still further scheme of the invention: in the step 3), the water is added for 2 to 3 times of decoction, 8 to 10 times of water is added for each time of decoction for 2 to 3 hours.
As a still further scheme of the invention: in the step 4), the concentration of the added ethanol is 30-40%, and the refrigeration time is 18-30 hours.
As a still further scheme of the invention: in the step 6), the refrigerating temperature is 2-6 ℃, and the refrigerating time is 15-25 hours.
As a still further scheme of the invention: in the step 7), the temperature for sterilization is 105-110 ℃, and the time for sterilization is 30-50 min.
Compared with the prior art, the invention has the beneficial effects that: the oral liquid is prepared from dendrobium officinale, bighead atractylodes rhizome, semen cuscutae, an antioxidant, astragalus membranaceus, wolfberry fruit, American ginseng, purslane, rhizoma anemarrhenae and desmodium through the processes of extraction, concentration, alcohol precipitation, centrifugation, preparation, re-centrifugation, filling, sterilization and the like, and during the preparation process, the alcohol precipitation technology is adopted to remove components such as tannic acid, protein and the like in the medicinal materials, so that a clear and transparent solution is obtained; in order to prevent the active ingredients such as polysaccharide, polyphenol, total flavone and the like of the product from being oxidized and decomposed to lose the efficacy, the invention particularly adds the antioxidant to ensure that the active ingredients of the product are not lost and decomposed; the invention is prepared into an oral liquid preparation formulation, is convenient to take, is beneficial to the quick absorption of effective components, achieves the effect of assisting in reducing blood sugar, and can prevent complications. The process and the dosage form of the invention are scientific and reasonable, and have obvious advantages.
Detailed Description
The oral liquid is prepared from dendrobium officinale, bighead atractylodes rhizome, semen cuscutae, an antioxidant, astragalus membranaceus, wolfberry fruit, American ginseng, purslane, rhizoma anemarrhenae and desmodium through the processes of extraction, concentration, alcohol precipitation, centrifugation, preparation, re-centrifugation, filling, sterilization and the like, and during the preparation process, the alcohol precipitation technology is adopted to remove components such as tannic acid, protein and the like in the medicinal materials, so that a clear and transparent solution is obtained; in order to prevent the active ingredients such as polysaccharide, polyphenol, total flavone and the like of the product from being oxidized and decomposed to lose the efficacy, the invention particularly adds the antioxidant to ensure that the active ingredients of the product are not lost and decomposed; the invention is prepared into an oral liquid preparation formulation, is convenient to take, is beneficial to the quick absorption of effective components, achieves the effect of assisting in reducing blood sugar, and can prevent complications. The process and the dosage form of the invention are scientific and reasonable, and have obvious advantages.
The technical solution of the present invention will be described in further detail with reference to specific embodiments.
Example 1
Weighing 8 parts of dendrobium officinale, 15 parts of bighead atractylodes rhizome, 12 parts of semen cuscutae, 1 part of antioxidant, 2 parts of astragalus membranaceus, 10 parts of wolfberry fruit, 8 parts of American ginseng, 9 parts of purslane, 5 parts of rhizoma anemarrhenae and 4 parts of desmodium in sequence according to the weight part ratio, wherein the antioxidant is selected from sodium ascorbate, sodium benzoate, phospholipid and potassium sorbate in a combination ratio of 2:1:2:1, and the water is purified water; pretreatment: pulverizing radix Panacis Quinquefolii, and sieving with 100 mesh sieve to obtain radix Panacis Quinquefolii powder; crushing the dendrobium officinale, and sieving with a 50-mesh sieve to obtain dendrobium officinale powder; extracting and concentrating: adding crushed American ginseng powder and dendrobium officinale powder and bighead atractylodes rhizome, semen cuscutae, astragalus membranaceus, wolfberry fruit, purslane, rhizoma anemarrhenae and desmodium into water for decoction, filtering, combining filtrates, concentrating under reduced pressure at-0.09 +/-0.01 MPa and 60 +/-5 ℃ to obtain clear paste, centrifuging, taking supernate, adding water for 2 times of decoction, adding 8 times of water for each time, and decocting for 2 hours; alcohol precipitation: adding ethanol into the obtained supernatant, refrigerating, centrifuging, recovering ethanol from the supernatant until the supernatant has no alcohol smell, and filtering to obtain solution I, wherein the step is to remove tannic acid, protein and other components in the medicinal materials to obtain clear and transparent solution, the concentration of the added ethanol is 30%, and the refrigerating time is 18 hours; preparing liquid: adding antioxidant into the obtained solution I, stirring for dissolving, adding water to obtain solution II, and adding antioxidant to keep the effective components of polysaccharide, polyphenol and total flavone from being oxidized and decomposed, thereby keeping the efficacy of the product; refrigerating, centrifuging and filtering: refrigerating the obtained solution II, centrifuging, filtering to obtain filtrate, refrigerating at low temperature at 2 deg.C for 15 hr to precipitate and maintain the activity of effective components; and (3) sterilization: sterilizing the obtained filtrate at high temperature of 105 ℃ for 30min to obtain the traditional Chinese medicine composition for assisting in reducing blood sugar.
Example 2
Weighing 10 parts of dendrobium officinale, 18 parts of bighead atractylodes rhizome, 13 parts of semen cuscutae, 2 parts of antioxidant, 3 parts of astragalus membranaceus, 12 parts of wolfberry fruit, 10 parts of American ginseng, 10 parts of purslane, 6 parts of rhizoma anemarrhenae and 5 parts of desmodium in sequence according to the weight part ratio, wherein the antioxidant is selected from sodium ascorbate, sodium benzoate, phospholipid and potassium sorbate in a combination ratio of 3:1:1:3, and the water is purified water; pretreatment: pulverizing radix Panacis Quinquefolii, and sieving with 100 mesh sieve to obtain radix Panacis Quinquefolii powder; crushing the dendrobium officinale, and sieving with a 50-mesh sieve to obtain dendrobium officinale powder; extracting and concentrating: adding crushed American ginseng powder and dendrobium officinale powder and bighead atractylodes rhizome, semen cuscutae, astragalus membranaceus, wolfberry fruit, purslane, rhizoma anemarrhenae and desmodium into water for decoction, filtering, combining filtrates, concentrating under reduced pressure at-0.09 +/-0.01 MPa and 60 +/-5 ℃ to obtain clear paste, centrifuging, taking supernate, adding water for decocting for 3 times, adding 9 times of water for each time, and decocting for 2.5 hours; alcohol precipitation: adding ethanol into the obtained supernatant, refrigerating, centrifuging, recovering ethanol from the supernatant until the supernatant has no alcohol smell, and filtering to obtain solution I, wherein the step is to remove tannic acid, protein and other components in the medicinal materials to obtain clear and transparent solution, the concentration of the added ethanol is 35%, and the refrigerating time is 20 hours; preparing liquid: adding antioxidant into the obtained solution I, stirring for dissolving, adding water to obtain solution II, and adding antioxidant to keep the effective components of polysaccharide, polyphenol and total flavone from being oxidized and decomposed, thereby keeping the efficacy of the product; refrigerating, centrifuging and filtering: refrigerating the obtained solution II, centrifuging, filtering to obtain filtrate, refrigerating at low temperature at 3 deg.C for 18 hr to precipitate and maintain the activity of effective components; and (3) sterilization: sterilizing the obtained filtrate at high temperature of 106 ℃ for 35min to obtain the traditional Chinese medicine composition for assisting in reducing blood sugar.
Example 3
Weighing 10 parts of dendrobium officinale, 18 parts of bighead atractylodes rhizome, 13 parts of semen cuscutae, 2 parts of antioxidant, 3 parts of astragalus membranaceus, 12 parts of wolfberry fruit, 10 parts of American ginseng, 10 parts of purslane, 6 parts of rhizoma anemarrhenae and 5 parts of desmodium in sequence according to the weight part ratio, wherein the antioxidant is selected from sodium ascorbate, sodium benzoate, phospholipid and potassium sorbate in a combination ratio of 3:1:1:3, and the water is purified water; pretreatment: pulverizing radix Panacis Quinquefolii, and sieving with 100 mesh sieve to obtain radix Panacis Quinquefolii powder; crushing the dendrobium officinale, and sieving with a 50-mesh sieve to obtain dendrobium officinale powder; extracting and concentrating: adding crushed American ginseng powder and dendrobium officinale powder and bighead atractylodes rhizome, semen cuscutae, astragalus membranaceus, wolfberry fruit, purslane, rhizoma anemarrhenae and desmodium into water for decoction, filtering, combining filtrates, concentrating under reduced pressure at-0.09 +/-0.01 MPa and 60 +/-5 ℃ to obtain clear paste, centrifuging, taking supernate, adding water for 2 times of decoction, adding 9 times of water for each time, and decocting for 2 hours; alcohol precipitation: adding ethanol into the obtained supernatant, refrigerating, centrifuging, recovering ethanol from the supernatant until the supernatant has no alcohol smell, and filtering to obtain solution I, wherein the step is to remove tannic acid, protein and other components in the medicinal materials to obtain clear and transparent solution, the concentration of the added ethanol is 40%, and the refrigerating time is 24 hours; preparing liquid: adding antioxidant into the obtained solution I, stirring for dissolving, adding water to obtain solution II, and adding antioxidant to keep the effective components of polysaccharide, polyphenol and total flavone from being oxidized and decomposed, thereby keeping the efficacy of the product; refrigerating, centrifuging and filtering: refrigerating the obtained solution II, centrifuging, filtering to obtain filtrate, refrigerating at low temperature at 5 deg.C for 20 hr to precipitate and maintain the activity of effective components; and (3) sterilization: sterilizing the obtained filtrate at high temperature of 108 ℃ for 40min to obtain the traditional Chinese medicine composition for assisting in reducing blood sugar.
Example 4
Weighing 12 parts of dendrobium officinale, 22 parts of bighead atractylodes rhizome, 14 parts of semen cuscutae, 1 part of antioxidant, 4 parts of astragalus membranaceus, 15 parts of wolfberry fruit, 12 parts of American ginseng, 12 parts of purslane, 8 parts of rhizoma anemarrhenae and 6 parts of desmodium in sequence according to the weight part ratio, wherein the antioxidant is selected from sodium ascorbate, and the water is purified water; pretreatment: pulverizing radix Panacis Quinquefolii, and sieving with 100 mesh sieve to obtain radix Panacis Quinquefolii powder; crushing the dendrobium officinale, and sieving with a 50-mesh sieve to obtain dendrobium officinale powder; extracting and concentrating: adding crushed American ginseng powder and dendrobium officinale powder and bighead atractylodes rhizome, semen cuscutae, astragalus membranaceus, wolfberry fruit, purslane, rhizoma anemarrhenae and desmodium into water for decoction, filtering, combining filtrates, concentrating under reduced pressure at-0.09 +/-0.01 MPa and 60 +/-5 ℃ to obtain clear paste, centrifuging, taking supernate, adding water for decocting for 3 times, adding 8 times of water for each time, and decocting for 3 hours; alcohol precipitation: adding ethanol into the obtained supernatant, refrigerating, centrifuging, recovering ethanol from the supernatant until the supernatant has no alcohol smell, and filtering to obtain solution I, wherein the step is to remove tannic acid, protein and other components in the medicinal materials to obtain clear and transparent solution, the concentration of the added ethanol is 34%, and the refrigerating time is 28 hours; preparing liquid: adding antioxidant into the obtained solution I, stirring for dissolving, adding water to obtain solution II, and adding antioxidant to keep the effective components of polysaccharide, polyphenol and total flavone from being oxidized and decomposed, thereby keeping the efficacy of the product; refrigerating, centrifuging and filtering: refrigerating the obtained solution II, centrifuging, filtering to obtain filtrate, refrigerating at low temperature at 4 deg.C for 22 hr to precipitate and maintain the activity of effective components; and (3) sterilization: sterilizing the obtained filtrate at 109 ℃ for 45min to obtain the traditional Chinese medicine composition for assisting in reducing blood sugar.
Example 5
Weighing 16 parts of dendrobium officinale, 28 parts of bighead atractylodes rhizome, 16 parts of semen cuscutae, 3 parts of antioxidant, 6 parts of astragalus membranaceus, 20 parts of wolfberry fruit, 16 parts of American ginseng, 16 parts of purslane, 10 parts of rhizoma anemarrhenae and 9 parts of desmodium in sequence according to the weight part ratio, wherein the antioxidant is selected from sodium ascorbate, and the water is purified water; pretreatment: pulverizing radix Panacis Quinquefolii, and sieving with 100 mesh sieve to obtain radix Panacis Quinquefolii powder; crushing the dendrobium officinale, and sieving with a 50-mesh sieve to obtain dendrobium officinale powder; extracting and concentrating: adding crushed American ginseng powder and dendrobium officinale powder and bighead atractylodes rhizome, semen cuscutae, astragalus membranaceus, wolfberry fruit, purslane, rhizoma anemarrhenae and desmodium into water for decoction, filtering, combining filtrates, concentrating under reduced pressure at-0.09 +/-0.01 MPa and 60 +/-5 ℃ to obtain clear paste, centrifuging, taking supernate, adding water for decocting for 3 times, adding 10 times of water for each time, and decocting for 3 hours; alcohol precipitation: adding ethanol into the obtained supernatant, refrigerating, centrifuging, recovering ethanol from the supernatant until the supernatant has no alcohol smell, and filtering to obtain solution I, wherein the step is to remove tannic acid, protein and other components in the medicinal materials to obtain clear and transparent solution, the concentration of the added ethanol is 40%, and the refrigerating time is 30 hours; preparing liquid: adding antioxidant into the obtained solution I, stirring for dissolving, adding water to obtain solution II, and adding antioxidant to keep the effective components of polysaccharide, polyphenol and total flavone from being oxidized and decomposed, thereby keeping the efficacy of the product; refrigerating, centrifuging and filtering: refrigerating the obtained solution II, centrifuging, filtering to obtain filtrate, refrigerating at low temperature at 6 deg.C for 25 hr to precipitate and maintain the activity of effective components; and (3) sterilization: sterilizing the obtained filtrate at high temperature of 110 ℃ for 50min to obtain the traditional Chinese medicine composition for assisting in reducing blood sugar.
While the preferred embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.
Claims (10)
1. A traditional Chinese medicine composition for assisting in reducing blood sugar is characterized by mainly comprising the following raw materials in parts by weight: 8-16 parts of dendrobium officinale, 15-28 parts of bighead atractylodes rhizome, 12-16 parts of semen cuscutae, 1-3 parts of antioxidant, 2-6 parts of astragalus membranaceus, 10-20 parts of wolfberry fruit, 8-16 parts of American ginseng, 9-16 parts of purslane, 5-10 parts of rhizoma anemarrhenae and 4-9 parts of longhairy antenoron herb.
2. The traditional Chinese medicine composition for assisting in reducing blood sugar according to claim 1, which is mainly composed of the following raw materials in parts by weight: 10-14 parts of dendrobium officinale, 20-24 parts of bighead atractylodes rhizome, 13-15 parts of semen cuscutae, 2-3 parts of antioxidant, 3-5 parts of astragalus membranaceus, 12-18 parts of wolfberry fruit, 10-14 parts of American ginseng, 11-17 parts of purslane, 7-9 parts of rhizoma anemarrhenae and 5-8 parts of desmodium.
3. The traditional Chinese medicine composition for assisting in reducing blood sugar according to claim 1 or 2, which is characterized by mainly comprising the following raw materials in parts by weight: 12 parts of dendrobium officinale, 22 parts of bighead atractylodes rhizome, 14 parts of semen cuscutae, 3 parts of antioxidant, 4 parts of astragalus membranaceus, 15 parts of wolfberry fruit, 12 parts of American ginseng, 14 parts of purslane, 8 parts of rhizoma anemarrhenae and 7 parts of desmodium.
4. The traditional Chinese medicine composition for assisting in reducing blood sugar according to claim 3, wherein the antioxidant is selected from any one or more of sodium ascorbate, sodium benzoate, phospholipid and potassium sorbate.
5. The traditional Chinese medicine composition for assisting in reducing blood sugar according to claim 4, wherein the antioxidant is sodium ascorbate.
6. The traditional Chinese medicine composition for assisting in reducing blood sugar according to claim 5, wherein the water is purified water.
7. The traditional Chinese medicine composition for assisting in reducing blood sugar according to claim 6, wherein the dosage form of the traditional Chinese medicine compound composition is oral.
8. A method for preparing the traditional Chinese medicine composition for assisting in reducing blood sugar according to any one of claims 1 to 7, which comprises the following steps:
1) weighing 8-16 parts of dendrobium officinale, 15-28 parts of bighead atractylodes rhizome, 12-16 parts of semen cuscutae, 1-3 parts of antioxidant, 2-6 parts of astragalus membranaceus, 10-20 parts of wolfberry fruit, 8-16 parts of American ginseng, 9-16 parts of purslane, 5-10 parts of rhizoma anemarrhenae and 4-9 parts of desmodium;
2) pretreatment: pulverizing radix Panacis Quinquefolii, and sieving with 100 mesh sieve to obtain radix Panacis Quinquefolii powder; crushing the dendrobium officinale, and sieving with a 50-mesh sieve to obtain dendrobium officinale powder;
3) extracting and concentrating: decocting the American ginseng powder and the dendrobium officinale powder obtained by crushing in the step 2) and the bighead atractylodes rhizome, the dodder seed, the astragalus root, the medlar, the purslane, the rhizoma anemarrhenae and the desmodium in water, filtering, combining the filtrates, concentrating under reduced pressure at-0.09 +/-0.01 MPa and 60 +/-5 ℃ to obtain clear paste, centrifuging, and taking supernatant;
4) alcohol precipitation: adding ethanol into the supernatant obtained in the step 3), refrigerating, centrifuging, recovering ethanol in the supernatant until no alcohol smell exists in the supernatant, and filtering to obtain a solution I, wherein the step aims at removing components such as tannic acid, protein and the like in the medicinal materials to obtain a clear and transparent solution;
5) preparing liquid: adding an antioxidant into the solution I obtained in the step 4), stirring for dissolving, adding water to obtain a solution II, wherein the antioxidant can keep the functional components of the polysaccharide, the polyphenol and the total flavone from being oxidized and decomposed, so that the efficacy of the product is kept;
6) refrigerating, centrifuging and filtering: refrigerating the solution II obtained in the step 5), centrifuging and filtering to obtain filtrate, and refrigerating the precipitate at low temperature to keep the activity of the effective components;
7) and (3) sterilization: sterilizing the filtrate obtained in the step 6) at high temperature to obtain the traditional Chinese medicine composition for assisting in reducing blood sugar.
9. The method for preparing the traditional Chinese medicine composition for assisting in reducing blood sugar according to claim 8, wherein in the step 3), the number of times of decocting with water is 2-3, 8-10 times of water is added each time, and the decoction is carried out for 2-3 hours; in the step 4), the concentration of the added ethanol is 30-40%, and the refrigeration time is 18-30 hours.
10. The method for preparing the traditional Chinese medicine composition for assisting in reducing blood sugar according to claim 9, wherein in the step 6), the refrigeration temperature is 2-6 ℃, and the refrigeration time is 15-25 hours; in the step 7), the temperature for sterilization is 105-110 ℃, and the time for sterilization is 30-50 min.
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| CN117530380A (en) * | 2023-12-13 | 2024-02-09 | 大冶康之堂农业发展有限公司 | Composite beverage with intestinal tract regulating effect and preparation method thereof |
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