CN112853523A - Antiviral hemostatic viscose fiber prepared from Chinese medicinal materials, and its preparation method - Google Patents
Antiviral hemostatic viscose fiber prepared from Chinese medicinal materials, and its preparation method Download PDFInfo
- Publication number
- CN112853523A CN112853523A CN202110445704.XA CN202110445704A CN112853523A CN 112853523 A CN112853523 A CN 112853523A CN 202110445704 A CN202110445704 A CN 202110445704A CN 112853523 A CN112853523 A CN 112853523A
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- CN
- China
- Prior art keywords
- hemostatic
- traditional chinese
- chinese medicine
- antiviral
- plant
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Links
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Classifications
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Abstract
The invention relates to the technical field of functional cellulose fiber, and discloses a preparation method of plant traditional Chinese medicine antiviral hemostatic viscose fiber, which comprises the following steps of preparation of plant traditional Chinese medicine antiviral hemostatic composition microcapsules, preparation of plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution and preparation of plant traditional Chinese medicine antiviral hemostatic viscose fiber, wherein the preparation method of the plant traditional Chinese medicine antiviral hemostatic composition microcapsules comprises the following steps: s1: preparing an emulsion of the antiviral and hemostatic composition of the Chinese herbal medicines; s2: preparing plant Chinese medicinal antivirus hemostatic composition microcapsule; the preparation of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the components of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent; the invention enhances the antiviral hemostatic function of the prepared viscose fiber, improves the content of effective components, increases the functionality, has the advantages of good antibacterial, antiviral and hemostatic functions, and is suitable for wide popularization and use.
Description
Technical Field
The invention relates to the technical field of functional cellulose fibers, in particular to a plant traditional Chinese medicine antiviral hemostatic viscose fiber prepared by taking plant traditional Chinese medicine antiviral hemostatic composition microcapsules and composition modification auxiliary agents as functional components and a preparation method thereof.
Background
Viscose fiber has the characteristics of moisture absorption, good air permeability and comfortable wearing, is one of important varieties of textile fiber, has been greatly developed in the aspects of antibacterial, antiviral and medical functions in recent years, and has obtained a favorable result.
Refer to Chinese patent CN201810487928.5 and disclose a sarcandra glabra antibacterial and antiviral cellulose fiber with good hygroscopicity and a preparation method thereof; the patent technology has the problems of unstable addition of an auxiliary agent, poor acid resistance and the like, and the prepared silicic acid composite colloid is directly added into an acid bath, so that the transparency of the acid bath is reduced, and the performance of fibers is reduced.
Refer to Chinese patent CN201710183270.4 and disclose a sarcandra glabra high-efficiency antibacterial antiviral cellulose fiber and a preparation method thereof; the chitosan-functional component composite particles prepared by the patent technology have poor stability, and the silicic acid composite colloid has reduced transparency after being added into an acid bath, thereby affecting the filtering performance, causing filtering difficulty and finally affecting the physical and mechanical properties of the fiber.
Refer to Chinese patent CN201410124416.4 to disclose an antiviral, antibacterial fiber and its preparation method and use; the patent technology mainly endows the fiber with antiviral and antibacterial functions in a post-finishing crosslinking grafting mode. The late graft crosslinking time is long, and the yield is influenced.
Refer to chinese patent CN200810039128.3 to disclose a method for preparing antiviral viscose fiber; the antiviral drug selected by the patent technology is mainly an anti-herpes drug acyclovir, and due to the fact that the viscose fiber is complex in production process, multiple in used chemical substances and harsh in forming conditions, the stability of the antiviral drug can be affected by direct addition, and the antiviral function of the fiber is affected.
Refer to Chinese patent CN200310101843.2 and disclose an antiviral fiber and its manufacturing method and use; although the technology of the patent has the adsorption of anion and cation groups, the acting force between the antibacterial substance and the fiber matrix is lacked, so that the function durability is poor.
The natural plant extract has rich biological functions, such as bacteriostasis, deodorization, hemostasis, anti-inflammation, heat clearing, detoxifying, virus resistance and the like; because the active molecules of the plant extracts have strong synergistic effect, a plurality of plant extracts with rich biological functions are reasonably and effectively used in a composite way, the biological characteristics of the respective active molecules can be fully exerted to the utmost extent, and the effect which cannot be achieved by a single plant extract is achieved, so that the unexpected effect is achieved.
The honeysuckle is famous for wide medicinal value since ancient times, the extract of the honeysuckle contains chlorogenic acid, luteolin glycoside and other pharmacological active ingredients, almost has no toxicity, has stronger inhabitation power to hemolytic streptococcus, staphylococcus aureus and other pathogenic bacteria and upper respiratory tract infection pathogenic viruses and the like, and can also enhance the immunity, diminish inflammation, relieve fever, stop bleeding (blood coagulation) and other effects; fructus forsythiae has pharmacological effects of resisting bacteria, tonifying heart, promoting urination, relieving vomiting and the like, can inhibit typhoid bacillus, escherichia coli, staphylococcus, streptococcus and the like, is commonly used for treating acute wind-heat type common cold, carbuncle swelling sore and other symptoms, and is a main raw material of a traditional Chinese medicine preparation such as Shuanghuanglian oral liquid, heat-clearing and detoxifying oral liquid and the like; the isatis root is an excellent Chinese medicinal material and has the effects of resisting bacteria, viruses and tumors and improving the immunologic function; the radix scutellariae extract contains a plurality of active substances such as radix scutellariae glycerol, baicalein and the like, has a plurality of efficacies of clearing away heat and toxic materials, resisting bacteria, stopping bleeding, improving immunity and the like, and has excellent antibacterial effect on staphylococcus aureus, escherichia coli and candida albicans; the beautyberry grass contains a hemostatic component called flavonoid condensed tannin and has the effects of stopping bleeding, dissipating blood stasis and diminishing inflammation; the giant knotweed rhizome has the inhibition effect on staphylococcus aureus, streptococcus A or B, escherichia coli, herpes simplex virus, influenza virus and the like, and is an ideal good medicine for diminishing inflammation and resisting virus; rhizoma polygonati is a traditional Chinese medicine for tonifying middle-jiao and qi, belongs to a medicine and food dual-purpose traditional Chinese medicine, has the functions of resisting pathogenic microorganisms, resisting fatigue, resisting oxidation, delaying senility, stopping bleeding and resisting virus, and is safe to take.
In view of the excellent performance of the plant traditional Chinese medicine, how to apply the plant traditional Chinese medicine to the functional modification of the viscose fiber to endow the viscose fiber with excellent functionality and endow the viscose fiber with functional durability through process adjustment has important significance; therefore, a preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber is provided.
Disclosure of Invention
The invention aims to overcome the defects in the prior art, and provides plant traditional Chinese medicine anti-virus hemostatic composition microcapsules and plant traditional Chinese medicine anti-virus hemostatic modification auxiliary agents which are used for preparing viscose fibers with anti-virus hemostatic functions and a preparation method of the viscose fibers with the anti-virus hemostatic functions.
In order to achieve the purpose, the invention provides the following technical scheme: a preparation method of plant traditional Chinese medicine antiviral hemostatic viscose fiber comprises the steps of preparation of plant traditional Chinese medicine antiviral hemostatic composition microcapsules, preparation of plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution and preparation of plant traditional Chinese medicine antiviral hemostatic viscose fiber, wherein the preparation of the plant traditional Chinese medicine antiviral hemostatic composition microcapsules comprises the following steps:
the first step is as follows: preparing an emulsion of the antiviral and hemostatic composition of the Chinese herbal medicines;
The preparation method of the plant traditional Chinese medicine antiviral and hemostatic composition emulsion comprises the following specific steps:
s1: firstly, adding an emulsifier into distilled water, and mixing for 30-50 min at a stirring speed of 800-1200 r/min and a temperature of 20-30 ℃ to obtain an emulsifier solution with a mass fraction of 1.8% -3.0%; the emulsifier is one of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate and polystyrene-maleic anhydride sodium salt;
s2: then respectively and uniformly mixing the capsule core material oily plant antiviral and hemostatic composition and the capsule wall material at the temperature of 20-30 ℃ and the stirring speed of 800-1200 r/min to respectively form a uniform capsule core material mixture and a uniform capsule wall material mixture; the capsule core material is an oily plant antiviral and hemostatic composition, and is an oily composition prepared from honeysuckle extract, sealwort extract and scutellaria extract, wherein the mass ratio of the honeysuckle extract to the polygonatum extract to the scutellaria extract is 1: 1-2: 1-2; the capsule wall material is a mixture of isophorone diisocyanate and polyaspartic acid ester, and the mass ratio of the materials is 1: 1-3; the mass ratio of the capsule core material to the capsule wall material is 1-2: 1;
s3: adding the prepared capsule core material mixture into the capsule wall material mixture, and continuously mixing for 25-35 min at the same temperature and stirring speed to form a uniform capsule core-capsule wall material mixture;
S4: then adding the prepared capsule core-capsule wall material mixture into a prepared emulsifier solution, and carrying out high-speed shearing, emulsifying and dispersing at the temperature of 30-38 ℃ and the rotating speed of 2500-2850 r/min until the particle size D90 of the emulsion is less than or equal to 1.952 μm to obtain the plant traditional Chinese medicine antiviral and hemostatic composition emulsion, wherein the mass fraction of the capsule core-capsule wall material in the emulsion is 35-50%;
the second step is that: preparing plant Chinese medicinal antivirus hemostatic composition microcapsule;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic composition microcapsule comprises the following specific steps:
s1: firstly, gradually raising the temperature of the prepared finished product plant traditional Chinese medicine antiviral and hemostatic composition emulsion to 85-92 ℃, and continuously reacting for 3.5-4.5 hours at a stirring speed of 300-600 r/min to obtain microcapsules taking the oily plant traditional Chinese medicine antiviral and hemostatic composition as capsule cores, wherein the particle size D90 is less than or equal to 2.156 microns;
s2: then defoaming to obtain the finished product plant traditional Chinese medicine antiviral hemostatic composition microcapsule, and storing for later use.
Preferably, the preparation of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following steps:
the first step is as follows: the composition of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent;
the antiviral hemostatic modifying auxiliary agent for the plant traditional Chinese medicines comprises the following components in parts by weight: honeysuckle extract, forsythia extract, isatis root extract, scutellaria extract, phyllostachys pubescens extract, polygonum cuspidatum extract and polygonatum sibiricum extract; the plant traditional Chinese medicine is prepared by the existing method or obtained by purchasing, and the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent comprises the following components in parts by weight: 15-20 parts of honeysuckle extract, 15-20 parts of fructus forsythiae extract, 20-25 parts of radix isatidis extract, 10-15 parts of scutellaria baicalensis extract, 25-30 parts of phyllostachys pubescens extract, 5-10 parts of polygonum cuspidatum extract and 10-20 parts of rhizoma polygonati extract;
The second step is that: preparing an antiviral and hemostatic modified auxiliary agent solution of the plant traditional Chinese medicine;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following specific steps:
s1: firstly, under the conditions that the temperature is 40-60 ℃ and the rotating speed is 200-400 r/min, the pH value of distilled water is adjusted to be 7.0-8.0, the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent obtained by mixing is added for dissolution, the mass fraction is 15-20%, the dissolution time is 1.5-2.5 h, and the temperature is cooled to 20-25 ℃;
s2: then, the filtering area is 150-200 m2Filtering with a plate-and-frame filter, wherein the filter medium is polypropylene felt and silk, the filter pore diameter is 15-30 μm, filtering to obtain the finished plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution, and storing for later use.
Preferably, the preparation of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following steps:
the first step is as follows: preparing a spinning solution before spinning viscose fibers;
the preparation method of the viscose fiber pre-spinning solution comprises the following specific steps:
s1: firstly, cellulose pulp is taken as a raw material, a viscose fiber spinning solution is prepared by a conventional viscose preparation process, and the viscose fiber spinning solution comprises the following components: type A cellulose: 8.92-9.10%, sodium hydroxide: 5.50% -5.65%, and pore-forming agent is added into the viscose fiber spinning dope; the pore-forming agent is prepared by mixing one of sodium carbonate or sodium bicarbonate with polyvinyl alcohol with the average polymerization degree of 200-600, wherein the addition amount of the sodium carbonate or the sodium bicarbonate is 3.5-5.5% of the content of alpha cellulose in the viscose spinning dope, the addition amount of the polyvinyl alcohol is 5.0-10.0% of the content of the alpha cellulose in the viscose spinning dope, and the pore-forming agent is uniformly mixed and defoamed for later use;
S2: then utilizing injection equipment before spinning, calculating the stored finished product plant Chinese medicinal antiviral hemostatic composition microcapsule which accounts for a certain proportion of the content of alpha cellulose in the viscose spinning solution according to effective components, adding the microcapsule into the viscose spinning solution, and preparing to obtain spinning solution before spinning; the plant traditional Chinese medicine anti-virus hemostatic composition microcapsule accounts for 10.0 to 15.0 percent of the content of alpha cellulose in the viscose by the effective component;
the second step is that: preparing the antiviral hemostatic viscose fiber of the traditional Chinese medicine of the plant;
the preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following specific steps:
s1: firstly, spinning the blended spinning solution through an adjusted coagulating bath to obtain primary tows, and drafting the primary tows to obtain formed tows;
s2: then, the surface and the interior of the prepared functional cellulose fiber contain more holes by utilizing the action of gas generated by the pore-forming agent and the dissolution action of polyvinyl alcohol so as to facilitate the adsorption of the subsequent functional auxiliary agent;
s3: then, a mild desulfurization process, a functional additive adsorption process, an oiling process and a multi-section multi-mode drying process are utilized to further enhance the grafting and crosslinking combination of the effective components and the cellulose fiber matrix, increase the content of the effective components and improve the functionality; the functionality of the fiber is ensured from two aspects of spinning and fiber after-finishing.
Preferably, the coagulating bath comprises 90-105 g/L of sulfuric acid and 285-300 g/L of sodium sulfate, zinc sulfate is not used, and the temperature is 45-50 ℃; the desulfurization bath comprises: na (Na)2SO34.0-6.0 g/L, and the temperature is 65-85 ℃; the functional additive used in the functional additive adsorption process is prepared by blending an antiviral and hemostatic modification additive solution of traditional Chinese herbal medicine plants and citric acid or butyl tetracarboxylic acid, wherein the mass ratio of the active ingredient content of the antiviral and hemostatic modification additive solution of traditional Chinese herbal medicine plants to the citric acid or butyl tetracarboxylic acid is 1: 1-2, enhancing the adsorption effect by using the holes caused by the pore-forming agent.
Preferably, the oiling process adopts an oil bath, and the oil bath: 3.0-6.0 g/L, and the temperature is 45-55 ℃; the drying process comprises the following steps: microwave drying is adopted at the front drying stage, the microwave frequency is 1260-1550 MHz, the microwave drying time is 15-20 min, and the water content of the cellulose fiber after microwave drying is 15.5% -18.5%; the rear section adopts a steam drying process, and the drying temperature is as follows: and (3) drying at 95-110 ℃ for 20-30 min, wherein the water content of the fiber is 8.5% -10.5%.
The invention has the technical effects and advantages that:
1. the surface and the interior of the prepared fiber both contain the plant traditional Chinese medicine with the functions of resisting virus and stopping bleeding, the content of functional components in the fiber is increased by adding the plant traditional Chinese medicine antiviral and stopping bleeding composition microcapsule in the spinning process and adsorbing by utilizing the plant traditional Chinese medicine antiviral and stopping bleeding modification auxiliary agent in the scouring process, and the antiviral and stopping bleeding functions of the prepared viscose fiber are enhanced.
2. The pore-forming agent is added into the spinning solution, and then gas decomposition and loss are carried out in the forming process, so that a large number of holes are formed on the surface and inside of the fiber, and the adsorption quantity of the subsequent plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent is increased. Through microwave drying, the functional components are further permeated into the viscose fibers by microwaves, and the loss of the functional components is reduced by utilizing the cross-linking effect of citric acid or butyl tetracarboxylic acid and a viscose fiber matrix in the drying process, so that the content of effective components is improved, and the functionality is increased.
3. The viscose fiber prepared by the invention has good antibacterial, antiviral and hemostatic functions. Compared with the conventional viscose fiber, the composite viscose fiber has the inhibition rate of 88.3-93.6 percent on staphylococcus aureus, 87.5-93.8 percent on escherichia coli and 86.2-90.2 percent on candida albicans (GB/T20944.3-2008, evaluation No. 3 part of antibacterial performance of textiles: oscillation method); the antiviral activity value of the compound on influenza virus (HIN1) is 2.8-4.1, and the antiviral activity rate is 99.5-99.9%. (ISO18184-2019 "antiviral textiles test Standard"; the fiber has good hemostatic effect, and the blood coagulation effect is characterized by a blood coagulation index BCI which is less than or equal to 28.3 (test method: measuring the value of (A) of blood after the hemostatic material is put in by an ultraviolet spectrophotometer, taking a blank group as a reference, the BCI =100 xA sample/reference sample, the BCI is less than or equal to 30, and the lower the BCI is, the better the blood coagulation effect is).
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
A preparation method of plant traditional Chinese medicine antiviral hemostatic viscose fiber comprises the steps of preparation of plant traditional Chinese medicine antiviral hemostatic composition microcapsules, preparation of plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution and preparation of plant traditional Chinese medicine antiviral hemostatic viscose fiber, wherein the preparation of the plant traditional Chinese medicine antiviral hemostatic composition microcapsules comprises the following steps:
the first step is as follows: preparing an emulsion of the antiviral and hemostatic composition of the Chinese herbal medicines;
the preparation method of the plant traditional Chinese medicine antiviral and hemostatic composition emulsion comprises the following specific steps:
s1: firstly, adding an emulsifier into distilled water, and mixing for 50min at a stirring speed of 800r/min and a temperature of 30 ℃ to obtain an emulsifier solution with the mass fraction of 1.8%, wherein the emulsifier is sodium dodecyl sulfate;
S2: then respectively and uniformly mixing the oily plant antiviral and hemostatic composition as capsule core material and the capsule wall material at the temperature of 20 ℃ and the stirring speed of 1200r/min to respectively form a uniform capsule core material mixture and a uniform capsule wall material mixture; the capsule core material is an oily plant antiviral and hemostatic composition, and is an oily composition prepared from honeysuckle extract, sealwort extract and scutellaria extract, wherein the mass ratio of the honeysuckle extract to the polygonatum extract to the scutellaria extract is 1: 1: 1; the capsule wall material is a mixture of isophorone diisocyanate and polyaspartic acid ester, and the mass ratio of the capsule wall material to the polyaspartic acid ester is 1: 1; the mass ratio of the capsule core material to the capsule wall material is 1: 1;
s3: adding the prepared capsule core material mixture into the capsule wall material mixture, and continuously mixing for 25min at the same temperature and stirring speed to form a uniform capsule core-capsule wall material mixture;
s4: then adding the prepared capsule core-capsule wall material mixture into an emulsifier solution, and carrying out high-speed shearing, emulsifying and dispersing at the temperature of 30 ℃ and the rotating speed of 2500r/min until the particle size D90 of the emulsion is 1.952 μm to obtain the plant traditional Chinese medicine antiviral and hemostatic composition emulsion, wherein the mass fraction of the capsule core-capsule wall material in the emulsion is 35%;
The second step is that: preparing plant Chinese medicinal antivirus hemostatic composition microcapsule;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic composition microcapsule comprises the following specific steps:
s1: firstly, gradually raising the temperature of the prepared finished product plant traditional Chinese medicine antiviral and hemostatic composition emulsion to 85 ℃, and continuously reacting for 4.5 hours at a stirring speed of 600r/min to obtain microcapsules taking the oily plant traditional Chinese medicine antiviral and hemostatic composition as capsule cores, wherein the particle size D90 is 2.156 mu m;
s2: then defoaming to obtain the finished product plant traditional Chinese medicine antiviral hemostatic composition microcapsule, and storing for later use.
Further, the preparation of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following steps:
the first step is as follows: the composition of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent;
the antiviral hemostatic modifying auxiliary agent for the plant traditional Chinese medicines comprises the following components in parts by weight: honeysuckle extract, forsythia extract, isatis root extract, scutellaria extract, phyllostachys pubescens extract, polygonum cuspidatum extract and polygonatum sibiricum extract; the plant traditional Chinese medicine is prepared by the existing method or obtained by purchasing, and the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent comprises the following components in parts by weight: 15 parts of honeysuckle extract, 15 parts of forsythia extract, 20 parts of isatis root extract, 15 parts of scutellaria extract, 25 parts of phyllostachys chinensis extract, 5 parts of polygonum cuspidatum extract and 10 parts of polygonatum extract;
The second step is that: preparing an antiviral and hemostatic modified auxiliary agent solution of the plant traditional Chinese medicine;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following specific steps:
s1: firstly, under the conditions that the temperature is 60 ℃ and the rotating speed is 400r/min, the pH value of distilled water is adjusted to be 7.0, the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent obtained by mixing is added for dissolution, the mass fraction is 15 percent, the dissolution time is 1.5h, and the temperature is cooled to 20 ℃;
s2: then using a filter area of 150m2Filtering with plate-and-frame filter, wherein the filter medium is polypropylene felt and silk cloth, the filter pore diameter is 15 μm, filtering to obtain the final product of plant Chinese medicinal antivirus hemostasis modification auxiliary agent solution, and storing for use.
Further, the preparation of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following steps:
the first step is as follows: preparing a spinning solution before spinning viscose fibers;
the preparation method of the viscose fiber pre-spinning solution comprises the following specific steps:
s1: firstly, cellulose pulp is taken as a raw material, a viscose fiber spinning solution is prepared by a conventional viscose preparation process, and the viscose fiber spinning solution comprises the following components: type A cellulose: 8.92%, sodium hydroxide: 5.50 percent, and adding a pore-forming agent into the viscose fiber spinning solution; the pore-forming agent is prepared by mixing two substances, one of which is sodium carbonate, and the other of which is polyvinyl alcohol with the average polymerization degree of 300, wherein the addition amount of the sodium carbonate is 3.5 percent of the content of the alpha cellulose in the viscose spinning solution, the addition amount of the polyvinyl alcohol is 5.0 percent of the content of the alpha cellulose in the viscose spinning solution, and the pore-forming agent is uniformly mixed and defoamed for later use;
S2: then utilizing injection equipment before spinning, adding the stored finished product plant traditional Chinese medicine antiviral and hemostatic composition microcapsules which account for 10.0 percent of the content of alpha cellulose in the viscose spinning stock solution according to the effective components into the viscose spinning stock solution to prepare spinning solution before spinning;
the second step is that: preparing the antiviral hemostatic viscose fiber of the traditional Chinese medicine of the plant;
the preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following specific steps:
s1: firstly, spinning the blended spinning solution through an adjusted coagulating bath to obtain primary tows, and drafting the primary tows to obtain formed tows;
s2: then, the surface and the interior of the prepared functional cellulose fiber contain more holes by utilizing the action of gas generated by the pore-forming agent and the dissolution action of polyvinyl alcohol so as to facilitate the adsorption of the subsequent functional auxiliary agent;
s3: then, a mild desulfurization process, a functional additive adsorption process, an oiling process and a multi-section multi-mode drying process are utilized to further enhance the grafting and crosslinking combination of the effective components and the cellulose fiber matrix, increase the content of the effective components and improve the functionality; the functionality of the fiber is ensured from two aspects of spinning and fiber after-finishing.
Further, the coagulating bath comprises 90g/L of sulfuric acid, 285g/L of sodium sulfate and 50 ℃; the desulfurization bath comprises: na (Na)2SO34.0g/L at 85 ℃; the functional additive used in the functional additive adsorption process is plant Chinese medicinal antivirus hemostasis modified additive solution and lemonThe plant traditional Chinese medicine composition is prepared by blending citric acid, wherein the mass ratio of the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent to the citric acid is 1: 1.
further, the oiling process adopts an oil bath, and the oil bath comprises the following steps: 3.0g/L at 55 ℃; and (3) drying process: the drying front section adopts microwave drying, the microwave frequency is 1260MHz, the microwave drying time is 20min, and the water content of the cellulose fiber after microwave drying is 18.5%; the rear section adopts a steam drying process, and the drying temperature is as follows: drying at 110 deg.C for 20min, at which time the water content of the fiber is 10.5%.
The plant traditional Chinese medicine anti-virus hemostatic viscose fiber with the specification of 1.33dtex 38mm prepared by the embodiment has good antibacterial, anti-virus and hemostatic functions. The inhibition rate on staphylococcus aureus is 88.3 percent, the inhibition rate on escherichia coli is 87.5 percent, and the inhibition rate on candida albicans is 86.2 percent; the antiviral activity value of the compound on influenza virus (H1N1) is 2.8, and the antiviral activity rate is 99.5%; the fiber has good hemostatic effect, and BCI is 28.3.
Example two
A preparation method of plant traditional Chinese medicine antiviral hemostatic viscose fiber comprises the steps of preparation of plant traditional Chinese medicine antiviral hemostatic composition microcapsules, preparation of plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution and preparation of plant traditional Chinese medicine antiviral hemostatic viscose fiber, wherein the preparation of the plant traditional Chinese medicine antiviral hemostatic composition microcapsules comprises the following steps:
the first step is as follows: preparing an emulsion of the antiviral and hemostatic composition of the Chinese herbal medicines;
the preparation method of the plant traditional Chinese medicine antiviral and hemostatic composition emulsion comprises the following specific steps:
s1: firstly, adding an emulsifier into distilled water, and mixing for 43min at a stirring speed of 930r/min and a temperature of 23 ℃ to obtain an emulsifier solution with the mass fraction of 2.2%, wherein the emulsifier is sodium dodecyl benzene sulfonate;
s2: then respectively and uniformly mixing the oily plant antiviral and hemostatic composition as capsule core material and the capsule wall material at 23 ℃ and a stirring speed of 1150r/min to respectively form a uniform capsule core material mixture and a uniform capsule wall material mixture; the capsule core material is an oily plant antiviral and hemostatic composition, and is an oily composition prepared from honeysuckle extract, sealwort extract and scutellaria extract, wherein the mass ratio of the honeysuckle extract to the polygonatum extract to the scutellaria extract is 1: 1: 2; the capsule wall material is a mixture of isophorone diisocyanate and polyaspartic acid ester, and the mass ratio of the capsule wall material to the polyaspartic acid ester is 1: 1.5; the mass ratio of the capsule core material to the capsule wall material is 1.2: 1;
S3: adding the prepared capsule core material mixture into the capsule wall material mixture, and continuously mixing for 33min at the same temperature and stirring speed to form a uniform capsule core-capsule wall material mixture;
s4: then adding the prepared capsule core-capsule wall material mixture into an emulsifier solution, and carrying out high-speed shearing, emulsifying and dispersing at the temperature of 33 ℃ and the rotating speed of 2610r/min until the particle size D90 of the emulsion is 1.795 mu m to obtain the plant traditional Chinese medicine antiviral and hemostatic composition emulsion, wherein the mass fraction of the capsule core-capsule wall material in the emulsion is 38%;
the second step is that: preparing plant Chinese medicinal antivirus hemostatic composition microcapsule;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic composition microcapsule comprises the following specific steps:
s1: firstly, gradually raising the temperature of the prepared finished product plant traditional Chinese medicine antiviral and hemostatic composition emulsion to 90 ℃, and continuously reacting for 4.2 hours at a stirring speed of 500r/min to obtain the microcapsule taking the oily plant traditional Chinese medicine antiviral and hemostatic composition as a capsule core, wherein the particle size D90 is 1.965 mu m;
s2: then defoaming to obtain the finished product plant traditional Chinese medicine antiviral hemostatic composition microcapsule, and storing for later use.
Further, the preparation of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following steps:
The first step is as follows: the composition of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent;
the antiviral hemostatic modifying auxiliary agent for the plant traditional Chinese medicines comprises the following components in parts by weight: honeysuckle extract, forsythia extract, isatis root extract, scutellaria extract, phyllostachys pubescens extract, polygonum cuspidatum extract and polygonatum sibiricum extract; the plant traditional Chinese medicine is prepared by the existing method or obtained by purchasing, and the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent comprises the following components in parts by weight: 17 parts of honeysuckle extract, 16 parts of forsythia extract, 22 parts of isatis root extract, 13 parts of scutellaria extract, 26 parts of phyllostachys pubescens extract, 8 parts of polygonum cuspidatum extract and 13 parts of polygonatum extract;
the second step is that: preparing an antiviral and hemostatic modified auxiliary agent solution of the plant traditional Chinese medicine;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following specific steps:
s1: firstly, under the conditions that the temperature is 55 ℃ and the rotating speed is 360r/min, the pH value of distilled water is adjusted to be 7.3, the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent obtained by mixing is added for dissolution, the mass fraction is 16.5 percent, the dissolution time is 1.8h, and the temperature is cooled to 22 ℃;
s2: then using a filter area of 170m 2 Filtering with plate-and-frame filter, wherein the filter medium is polypropylene felt and silk cloth, the filter pore diameter is 18 μm, filtering to obtain the final product of plant Chinese medicinal antivirus hemostasis modification auxiliary agent solution, and storing for use.
Further, the preparation of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following steps:
the first step is as follows: preparing a spinning solution before spinning viscose fibers;
the preparation method of the viscose fiber pre-spinning solution comprises the following specific steps:
s1: firstly, cellulose pulp is taken as a raw material, a viscose fiber spinning solution is prepared by a conventional viscose preparation process, and the viscose fiber spinning solution comprises the following components: type A cellulose: 8.98%, sodium hydroxide: 5.55 percent, and pore-forming agent is added into the viscose fiber spinning solution; the pore-forming agent is prepared by mixing two substances, namely sodium bicarbonate and polyvinyl alcohol with the average polymerization degree of 350, wherein the addition amount of the sodium bicarbonate is 4.2 percent of the content of alpha cellulose in the viscose spinning dope, the addition amount of the polyvinyl alcohol is 6.5 percent of the content of the alpha cellulose in the viscose spinning dope, and the pore-forming agent is uniformly mixed and defoamed for later use;
s2: then utilizing injection equipment before spinning, adding the stored finished product plant traditional Chinese medicine antiviral and hemostatic composition microcapsules which account for 11.8 percent of the content of alpha cellulose in the viscose spinning stock solution according to the effective components into the viscose spinning stock solution to prepare spinning solution before spinning;
The second step is that: preparing the antiviral hemostatic viscose fiber of the traditional Chinese medicine of the plant;
the preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following specific steps:
s1: firstly, spinning the blended spinning solution through an adjusted coagulating bath to obtain primary tows, and drafting the primary tows to obtain formed tows;
s2: then, the surface and the interior of the prepared functional cellulose fiber contain more holes by utilizing the action of gas generated by the pore-forming agent and the dissolution action of polyvinyl alcohol so as to facilitate the adsorption of the subsequent functional auxiliary agent;
s3: then, a mild desulfurization process, a functional additive adsorption process, an oiling process and a multi-section multi-mode drying process are utilized to further enhance the grafting and crosslinking combination of the effective components and the cellulose fiber matrix, increase the content of the effective components and improve the functionality; the functionality of the fiber is ensured from two aspects of spinning and fiber after-finishing.
Further, the coagulating bath comprises 94g/L of sulfuric acid, 290g/L of sodium sulfate and 48 ℃; the desulfurization bath comprises: na (Na)2SO34.8g/L, temperature 68 ℃; the functional additive used in the functional additive adsorption process is prepared by blending plant traditional Chinese medicine antiviral hemostasis modification additive solution and citric acid, wherein the mass ratio of the plant traditional Chinese medicine antiviral hemostasis modification additive to the citric acid is 1: 1.5.
Further, the oiling process adopts an oil bath, and the oil bath comprises the following steps: 3.8g/L, temperature 48 ℃; and (3) drying process: the drying front section adopts microwave drying, the microwave frequency is 1310MHz, the microwave drying time is 18.5min, and the water content of the cellulose fiber after microwave drying is 17.8%; the rear section adopts a steam drying process, and the drying temperature is as follows: drying at 106 deg.C for 23min, at which time the water content of the fiber was 9.1%.
The plant traditional Chinese medicine anti-virus hemostatic viscose fiber with the specification of 1.56dtex 38mm prepared by the embodiment has good antibacterial, anti-virus and hemostatic functions. The inhibition rate on staphylococcus aureus is 89.5%, the inhibition rate on escherichia coli is 88.9%, and the inhibition rate on candida albicans is 87.1%; the antiviral activity value of the compound on influenza virus (H1N1) is 3.3, and the antiviral activity rate is 99.6%; the fiber has good hemostatic effect, and BCI is 26.1.
EXAMPLE III
A preparation method of plant traditional Chinese medicine antiviral hemostatic viscose fiber comprises the steps of preparation of plant traditional Chinese medicine antiviral hemostatic composition microcapsules, preparation of plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution and preparation of plant traditional Chinese medicine antiviral hemostatic viscose fiber, wherein the preparation of the plant traditional Chinese medicine antiviral hemostatic composition microcapsules comprises the following steps:
The first step is as follows: preparing an emulsion of the antiviral and hemostatic composition of the Chinese herbal medicines;
the preparation method of the plant traditional Chinese medicine antiviral and hemostatic composition emulsion comprises the following specific steps:
s1: firstly, adding an emulsifier into distilled water, and mixing for 39min at a stirring speed of 1050r/min and a temperature of 26 ℃ to obtain an emulsifier solution with the mass fraction of 2.5%, wherein the emulsifier is sodium dodecyl benzene sulfonate;
s2: then respectively and uniformly mixing the oily plant antiviral and hemostatic composition as capsule core material and the capsule wall material at the temperature of 25 ℃ and the stirring speed of 980r/min to respectively form a uniform capsule core material mixture and a uniform capsule wall material mixture; the capsule core material is an oily plant antiviral and hemostatic composition, and is an oily composition prepared from honeysuckle extract, sealwort extract and scutellaria extract, wherein the mass ratio of the honeysuckle extract to the polygonatum extract to the scutellaria extract is 1: 2: 1; the capsule wall material is a mixture of isophorone diisocyanate and polyaspartic acid ester, and the mass ratio of the capsule wall material to the polyaspartic acid ester is 1: 2; the mass ratio of the capsule core material to the capsule wall material is 1.5: 1;
s3: adding the prepared capsule core material mixture into the capsule wall material mixture, and continuously mixing for 31min at the same temperature and stirring speed to form a uniform capsule core-capsule wall material mixture;
S4: then adding the prepared capsule core-capsule wall material mixture into an emulsifier solution, and carrying out high-speed shearing, emulsifying and dispersing at 35 ℃ and at a rotating speed of 2700r/min until the particle size D90 of the emulsion is 1.890 mu m to obtain the plant traditional Chinese medicine antiviral and hemostatic composition emulsion, wherein the mass fraction of the capsule core-capsule wall material in the emulsion is 42%;
the second step is that: preparing plant Chinese medicinal antivirus hemostatic composition microcapsule;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic composition microcapsule comprises the following specific steps:
s1: firstly, gradually raising the temperature of the prepared finished product plant traditional Chinese medicine antiviral and hemostatic composition emulsion to 88 ℃, and continuously reacting for 4.0h at the stirring speed of 450r/min to obtain microcapsules taking the oily plant traditional Chinese medicine antiviral and hemostatic composition as capsule cores, wherein the particle size D90 is 2.038 mu m;
s2: and then defoaming to obtain the finished product of the plant traditional Chinese medicine antiviral hemostatic composition microcapsule, and storing for later use.
Further, the preparation of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following steps:
the first step is as follows: the composition of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent;
the antiviral hemostatic modifying auxiliary agent for the plant traditional Chinese medicines comprises the following components in parts by weight: honeysuckle extract, forsythia extract, isatis root extract, scutellaria extract, phyllostachys pubescens extract, polygonum cuspidatum extract and polygonatum sibiricum extract; the plant traditional Chinese medicine is prepared by the existing method or obtained by purchasing, and the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent comprises the following components in parts by weight: 18 parts of honeysuckle extract, 18 parts of forsythia extract, 23 parts of isatis root extract, 12 parts of scutellaria extract, 27 parts of phyllostachys chinensis extract, 8 parts of polygonum cuspidatum extract and 15 parts of polygonatum extract;
The second step is that: preparing an antiviral and hemostatic modified auxiliary agent solution of the plant traditional Chinese medicine;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following specific steps:
s1: firstly, under the conditions that the temperature is 52 ℃ and the rotating speed is 310r/min, the pH value of distilled water is adjusted to be 7.5, the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent obtained by mixing is added for dissolution, the mass fraction is 18.2 percent, the dissolution time is 2.0h, and the temperature is cooled to 23.5 ℃;
s2: then using a filter area of 180m2 Filtering with plate-and-frame filter, wherein the filter medium is polypropylene felt and silk cloth, the filter pore diameter is 25 μm, filtering to obtain the final product of plant Chinese medicinal antivirus hemostasis modification auxiliary agent solution, and storing for use.
Further, the preparation of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following steps:
the first step is as follows: preparing a spinning solution before spinning viscose fibers;
the preparation method of the viscose fiber pre-spinning solution comprises the following specific steps:
s1: firstly, cellulose pulp is taken as a raw material, a viscose fiber spinning solution is prepared by a conventional viscose preparation process, and the viscose fiber spinning solution comprises the following components: type A cellulose: 9.06%, sodium hydroxide: 5.58 percent, and adding a pore-forming agent into the viscose fiber spinning solution; the pore-forming agent is prepared by mixing two substances, namely sodium bicarbonate and polyvinyl alcohol with the average polymerization degree of 450, wherein the addition amount of the sodium bicarbonate is 4.7 percent of the content of alpha cellulose in the viscose spinning dope, the addition amount of the polyvinyl alcohol is 8.0 percent of the content of the alpha cellulose in the viscose spinning dope, and the pore-forming agent is uniformly mixed and defoamed for later use;
S2: then utilizing injection equipment before spinning, adding the stored finished product plant traditional Chinese medicine antiviral and hemostatic composition microcapsules accounting for 12.5 percent of the content of alpha cellulose in the viscose spinning stock solution according to effective components into the viscose spinning stock solution to prepare spinning solution before spinning;
the second step is that: preparing the antiviral hemostatic viscose fiber of the traditional Chinese medicine of the plant;
the preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following specific steps:
s1: firstly, spinning the blended spinning solution through an adjusted coagulating bath to obtain primary tows, and drafting the primary tows to obtain formed tows;
s2: then, the surface and the interior of the prepared functional cellulose fiber contain more holes by utilizing the action of gas generated by the pore-forming agent and the dissolution action of polyvinyl alcohol so as to facilitate the adsorption of the subsequent functional auxiliary agent;
s3: then, a mild desulfurization process, a functional additive adsorption process, an oiling process and a multi-section multi-mode drying process are utilized to further enhance the grafting and crosslinking combination of the effective components and the cellulose fiber matrix, increase the content of the effective components and improve the functionality; the functionality of the fiber is ensured from two aspects of spinning and fiber after-finishing.
Further, the coagulating bath comprises 98g/L of sulfuric acid, 295g/L of sodium sulfate and 47 ℃; the desulfurization bath comprises: na (Na)2SO35.5g/L, temperature 72 ℃; the functional additive used in the functional additive adsorption process is prepared by blending plant traditional Chinese medicine antiviral hemostasis modification additive solution and citric acid, wherein the mass ratio of the plant traditional Chinese medicine antiviral hemostasis modification additive to the citric acid is 1: 1.5.
further, the oiling process adopts an oil bath, and the oil bath comprises the following steps: 4.6g/L, temperature 51 ℃; and (3) drying process: the drying front section adopts microwave drying, the microwave frequency is 1390MHz, the microwave drying time is 18min, and the water content of the cellulose fiber after microwave drying is 17.2%; the rear section adopts a steam drying process, and the drying temperature is as follows: drying at 102 deg.C for 25min, at which time the water content of the fiber is 9.6%.
The plant traditional Chinese medicine anti-virus hemostatic viscose fiber with the specification of 1.56dtex 38mm prepared by the embodiment has good antibacterial, anti-virus and hemostatic functions. The inhibition rate on staphylococcus aureus is 90.8 percent, the inhibition rate on escherichia coli is 91.0 percent, and the inhibition rate on candida albicans is 87.8 percent; the antiviral activity value of the compound on influenza virus (H1N1) is 3.5, and the antiviral activity rate is 99.7%; the fiber has good hemostatic effect, and BCI is 25.0.
Example four
A preparation method of plant traditional Chinese medicine antiviral hemostatic viscose fiber comprises the steps of preparation of plant traditional Chinese medicine antiviral hemostatic composition microcapsules, preparation of plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution and preparation of plant traditional Chinese medicine antiviral hemostatic viscose fiber, wherein the preparation of the plant traditional Chinese medicine antiviral hemostatic composition microcapsules comprises the following steps:
the first step is as follows: preparing an emulsion of the antiviral and hemostatic composition of the Chinese herbal medicines;
the preparation method of the plant traditional Chinese medicine antiviral and hemostatic composition emulsion comprises the following specific steps:
s1: firstly, adding an emulsifier into distilled water, and mixing for 35min at a stirring speed of 1160r/min and a temperature of 28 ℃ to obtain an emulsifier solution with the mass fraction of 2.8%, wherein the emulsifier is sodium dodecyl benzene sulfonate;
s2: then respectively and uniformly mixing the oily plant antiviral and hemostatic composition as capsule core material and the capsule wall material at the temperature of 28 ℃ and the stirring speed of 880r/min to respectively form a uniform capsule core material mixture and a uniform capsule wall material mixture; the capsule core material is an oily plant antiviral and hemostatic composition, and is an oily composition prepared from honeysuckle extract, sealwort extract and scutellaria extract, wherein the mass ratio of the honeysuckle extract to the polygonatum extract to the scutellaria extract is 1: 1: 2; the capsule wall material is a mixture of isophorone diisocyanate and polyaspartic acid ester, and the mass ratio of the capsule wall material to the polyaspartic acid ester is 1: 2.5; the mass ratio of the capsule core material to the capsule wall material is 1.8: 1;
S3: adding the prepared capsule core material mixture into the capsule wall material mixture, and continuously mixing for 33min at the same temperature and stirring speed to form a uniform capsule core-capsule wall material mixture;
s4: then adding the prepared capsule core-capsule wall material mixture into an emulsifier solution, and carrying out high-speed shearing, emulsifying and dispersing at the temperature of 36.5 ℃ and the rotating speed of 2780r/min until the particle size D90 of the emulsion is 1.920 mu m to obtain the plant traditional Chinese medicine antiviral and hemostatic composition emulsion, wherein the mass fraction of the capsule core-capsule wall material in the emulsion is 46.5%;
the second step is that: preparing plant Chinese medicinal antivirus hemostatic composition microcapsule;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic composition microcapsule comprises the following specific steps:
s1: firstly, gradually raising the temperature of the prepared finished product plant traditional Chinese medicine antiviral and hemostatic composition emulsion to 90 ℃, and continuously reacting for 3.8 hours at a stirring speed of 380r/min to obtain microcapsules taking the oily plant traditional Chinese medicine antiviral and hemostatic composition as capsule cores, wherein the particle size D90 is 2.096 mu m;
s2: then defoaming to obtain the invented finished product plant Chinese medicine antivirus hemostatic composition (oily) microcapsule with capsule core, and storing for stand-by.
Further, the preparation of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following steps:
the first step is as follows: the composition of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent;
the antiviral hemostatic modifying auxiliary agent for the plant traditional Chinese medicines comprises the following components in parts by weight: honeysuckle extract, forsythia extract, isatis root extract, scutellaria extract, phyllostachys pubescens extract, polygonum cuspidatum extract and polygonatum sibiricum extract; the plant traditional Chinese medicine is prepared by the existing method or obtained by purchasing, and the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent comprises the following components in parts by weight: 19 parts of honeysuckle extract, 20 parts of forsythia extract, 22 parts of isatis root extract, 11 parts of scutellaria extract, 28 parts of phyllostachys pubescens extract, 6 parts of polygonum cuspidatum extract and 18 parts of polygonatum extract;
the second step is that: preparing an antiviral and hemostatic modified auxiliary agent solution of the plant traditional Chinese medicine;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following specific steps:
s1: firstly, under the conditions that the temperature is 45 ℃ and the rotating speed is 260r/min, the pH value of distilled water is adjusted to be 7.8, the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent obtained by mixing is added for dissolution, the mass fraction is 19.0 percent, the dissolution time is 2.2 hours, and the temperature is cooled to 24 ℃;
S2: then using a filter area of 180m2Filtering with plate-and-frame filter, wherein the filter medium is polypropylene felt and silk cloth, the filter pore diameter is 28 μm, filtering to obtain the final product of plant Chinese medicinal antivirus hemostasis modification auxiliary agent solution, and storing for use.
Further, the preparation of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following steps:
the first step is as follows: preparing a spinning solution before spinning viscose fibers;
the preparation method of the viscose fiber pre-spinning solution comprises the following specific steps:
s1: firstly, cellulose pulp is taken as a raw material, a viscose fiber spinning solution is prepared by a conventional viscose preparation process, and the viscose fiber spinning solution comprises the following components: type A cellulose: 9.03%, sodium hydroxide: 5.62 percent, and adding a pore-forming agent into the viscose fiber spinning solution; the pore-forming agent is prepared by mixing two substances, namely sodium bicarbonate and polyvinyl alcohol with the average polymerization degree of 500, wherein the addition amount of the sodium bicarbonate is 5.2 percent of the content of alpha cellulose in the viscose spinning dope, the addition amount of the polyvinyl alcohol is 9.0 percent of the content of the alpha cellulose in the viscose spinning dope, and the pore-forming agent is uniformly mixed and defoamed for later use;
s2: then utilizing injection equipment before spinning, adding microcapsules taking the preserved finished product plant traditional Chinese medicine antiviral hemostatic composition (oiliness) which accounts for 13.6 percent of the content of alpha cellulose in the viscose fiber spinning solution as capsule cores into the viscose fiber spinning solution according to effective components to prepare spinning solution before spinning;
The second step is that: preparing the antiviral hemostatic viscose fiber of the traditional Chinese medicine of the plant;
the preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following specific steps:
s1: firstly, spinning a spinning solution before spinning through an adjusted coagulating bath to obtain primary tows, and drafting the primary tows to obtain formed tows;
s2: then, the surface and the interior of the prepared functional cellulose fiber contain more holes by utilizing the action of gas generated by the pore-forming agent and the dissolution action of polyvinyl alcohol so as to facilitate the adsorption of the subsequent functional auxiliary agent;
s3: then, a mild desulfurization process, a functional additive adsorption process, an oiling process and a multi-section multi-mode drying process are utilized to further enhance the grafting and crosslinking combination of the effective components and the cellulose fiber matrix, increase the content of the effective components and improve the functionality; the functionality of the fiber is ensured from two aspects of spinning and fiber after-finishing.
Further, the coagulation bath includes sulfuric acid100g/L, 298g/L of sodium sulfate and 46 ℃ of temperature; the desulfurization bath comprises: na (Na)2SO35.8g/L, temperature 68 ℃; the functional additive used in the functional additive adsorption process is prepared by blending plant traditional Chinese medicine antiviral hemostasis modification additive solution and citric acid, wherein the mass ratio of the plant traditional Chinese medicine antiviral hemostasis modification additive to the citric acid is 1: 1.5.
Further, the oiling process adopts an oil bath, and the oil bath comprises the following steps: 5.2g/L at 47 ℃; and (3) drying process: the drying front section adopts microwave drying, the microwave frequency is 1450MHz, the microwave drying time is 16min, and the moisture content of the cellulose fiber after microwave drying is 16.3%; the rear section adopts a steam drying process, and the drying temperature is as follows: drying at 98 deg.C for 28min, at which time the water content of the fiber was 9.0%.
The plant traditional Chinese medicine anti-virus hemostatic viscose fiber with the specification of 1.56dtex 38mm prepared by the embodiment has good antibacterial, anti-virus and hemostatic functions. The inhibition rate on staphylococcus aureus is 92.3 percent, the inhibition rate on escherichia coli is 92.5 percent, and the inhibition rate on candida albicans is 88.6 percent; the antiviral activity value of the compound on influenza virus (H1N1) is 3.8, and the antiviral activity rate is 99.8%; the fiber has good hemostatic effect, and the BCI is 23.5.
EXAMPLE five
A preparation method of plant traditional Chinese medicine antiviral hemostatic viscose fiber comprises the steps of preparation of plant traditional Chinese medicine antiviral hemostatic composition microcapsules, preparation of plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution and preparation of plant traditional Chinese medicine antiviral hemostatic viscose fiber, wherein the preparation of the plant traditional Chinese medicine antiviral hemostatic composition microcapsules comprises the following steps:
The first step is as follows: preparing an emulsion of the antiviral and hemostatic composition of the Chinese herbal medicines;
the preparation method of the plant traditional Chinese medicine antiviral and hemostatic composition emulsion comprises the following specific steps:
s1: firstly, adding an emulsifier into distilled water, and mixing for 30min at a stirring speed of 1200r/min and a temperature of 20 ℃ to obtain an emulsifier solution with the mass fraction of 3.0%, wherein the emulsifier is polystyrene-maleic anhydride sodium salt;
s2: then respectively and uniformly mixing the oily plant antiviral and hemostatic composition as capsule core material and the capsule wall material at the temperature of 30 ℃ and the stirring speed of 800r/min to respectively form a uniform capsule core material mixture and a uniform capsule wall material mixture; the capsule core material is an oily plant antiviral and hemostatic composition, and is an oily composition prepared from honeysuckle extract, sealwort extract and scutellaria extract, wherein the mass ratio of the honeysuckle extract to the polygonatum extract to the scutellaria extract is 1: 2: 2; the capsule wall material is a mixture of isophorone diisocyanate and polyaspartic acid ester, and the mass ratio of the capsule wall material to the polyaspartic acid ester is 1: 3; the mass ratio of the capsule core material to the capsule wall material is 2: 1;
s3: adding the prepared capsule core material mixture into the capsule wall material mixture, and continuously mixing for 35min at the same temperature and stirring speed to form a uniform capsule core-capsule wall material mixture;
S4: then adding the prepared capsule core-capsule wall material mixture into an emulsifier solution, and carrying out high-speed shearing, emulsifying and dispersing at the temperature of 38 ℃ and the rotating speed of 2850r/min until the particle size D90 of the emulsion is 1.855 μm to obtain the plant traditional Chinese medicine antiviral and hemostatic composition emulsion, wherein the mass fraction of the capsule core-capsule wall material in the emulsion is 50%;
the second step is that: preparing plant Chinese medicinal antivirus hemostatic composition microcapsule;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic composition microcapsule comprises the following specific steps:
s1: firstly, gradually raising the temperature of the prepared finished product plant traditional Chinese medicine antiviral and hemostatic composition emulsion to 92 ℃, and continuously reacting for 3.5 hours at a stirring speed of 300r/min to obtain microcapsules taking the oily plant traditional Chinese medicine antiviral and hemostatic composition as capsule cores, wherein the particle size D90 is 2.065 mu m;
s2: and then defoaming to obtain the finished product of the plant traditional Chinese medicine antiviral hemostatic composition microcapsule, and storing for later use.
Further, the preparation of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following steps:
the first step is as follows: the composition of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent;
the antiviral hemostatic modifying auxiliary agent for the plant traditional Chinese medicines comprises the following components in parts by weight: honeysuckle extract, forsythia extract, isatis root extract, scutellaria extract, phyllostachys pubescens extract, polygonum cuspidatum extract and polygonatum sibiricum extract; the plant traditional Chinese medicine is prepared by the existing method or obtained by purchasing, and the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent comprises the following components in parts by weight: 20 parts of honeysuckle extract, 20 parts of forsythia extract, 25 parts of isatis root extract, 10 parts of scutellaria extract, 30 parts of phyllostachys chinensis extract, 10 parts of polygonum cuspidatum extract and 20 parts of polygonatum extract;
The second step is that: preparing an antiviral and hemostatic modified auxiliary agent solution of the plant traditional Chinese medicine;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following specific steps:
s1: firstly, under the conditions that the temperature is 40 ℃ and the rotating speed is 200r/min, the pH value of distilled water is adjusted to be 8.0, the plant traditional Chinese medicine antiviral and hemostatic modified auxiliary agent obtained by mixing is added for dissolution, the mass fraction of the plant traditional Chinese medicine antiviral and hemostatic modified auxiliary agent is 20 percent, the dissolution time is 2.5 hours, and the plant traditional Chinese medicine antiviral and hemostatic modified auxiliary agent is cooled to 25 ℃;
s2: then using a filter area of 200m2Filtering with plate-and-frame filter, wherein the filter medium is polypropylene felt and silk cloth, the filter pore diameter is 30 μm, filtering to obtain the final product of plant Chinese medicinal antivirus hemostasis modification auxiliary agent solution, and storing for use.
Further, the preparation of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following steps:
the first step is as follows: preparing a spinning solution before spinning viscose fibers;
the preparation method of the viscose fiber pre-spinning solution comprises the following specific steps:
s1: firstly, cellulose pulp is taken as a raw material, a viscose fiber spinning solution is prepared by a conventional viscose preparation process, and the viscose fiber spinning solution comprises the following components: type A cellulose: 9.10%, sodium hydroxide: 5.65 percent, and adding a pore-forming agent into the viscose fiber spinning solution; the pore-forming agent is prepared by mixing two substances, namely sodium carbonate and polyvinyl alcohol with the average polymerization degree of 600, wherein the addition amount of the sodium carbonate is 5.5% of the content of the alpha cellulose in the viscose spinning dope, the addition amount of the polyvinyl alcohol is 10.0% of the content of the alpha cellulose in the viscose spinning dope, and the pore-forming agent is uniformly mixed and defoamed for later use.
S2: then utilizing injection equipment before spinning, adding the stored finished product plant traditional Chinese medicine antiviral and hemostatic composition microcapsules accounting for 15.0 percent of the content of alpha cellulose in the viscose spinning stock solution according to effective components into the viscose spinning stock solution to prepare spinning solution before spinning;
the second step is that: preparing the antiviral hemostatic viscose fiber of the traditional Chinese medicine of the plant;
the preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following specific steps:
s1: firstly, spinning the blended spinning solution through an adjusted coagulating bath to obtain primary tows, and drafting the primary tows to obtain formed tows;
s2: then, the surface and the interior of the prepared functional cellulose fiber contain more holes by utilizing the action of gas generated by the pore-forming agent and the dissolution action of polyvinyl alcohol so as to facilitate the adsorption of the subsequent functional auxiliary agent;
s3: then, a mild desulfurization process, a functional additive adsorption process, an oiling process and a multi-section multi-mode drying process are utilized to further enhance the grafting and crosslinking combination of the effective components and the cellulose fiber matrix, increase the content of the effective components and improve the functionality; the functionality of the fiber is ensured from two aspects of spinning and fiber after-finishing.
Further, the coagulating bath comprises 105g/L of sulfuric acid, 300g/L of sodium sulfate and 45 ℃; the desulfurization bath comprises: na (Na)2SO36.0g/L, temperature 65 ℃; the functional additive used in the functional additive adsorption process is prepared by blending an antiviral and hemostatic modification additive solution of a traditional Chinese plant medicine and butyl tetracarboxylic acid, wherein the mass ratio of the antiviral and hemostatic modification additive solution of the traditional Chinese plant medicine to the butyl tetracarboxylic acid is 1: 2.
further, the oiling process adopts an oil bath, and the oil bath comprises the following steps: 6.0g/L at 45 ℃; and (3) drying process: the drying front section adopts microwave drying, the microwave frequency is 1550MHz, the microwave drying time is 15min, and the moisture content of the cellulose fiber after microwave drying is 15.5%; the rear section adopts a steam drying process, and the drying temperature is as follows: drying at 95 ℃ for 30min, wherein the water content of the fiber is 8.5%.
The plant traditional Chinese medicine anti-virus hemostatic viscose fiber with the specification of 1.67dtex 38mm prepared by the embodiment has good antibacterial, anti-virus and hemostatic functions. The inhibition rate on staphylococcus aureus is 93.6%, the inhibition rate on escherichia coli is 93.8%, and the inhibition rate on candida albicans is 90.2%; the antiviral activity value of the compound on influenza virus (H1N1) is 4.1, and the antiviral activity rate is 99.9%; the fiber has good hemostatic effect, and BCI is 22.1.
In summary, the following steps: the invention provides a preparation method of a plant traditional Chinese medicine antiviral hemostatic viscose fiber, which comprises the steps of firstly preparing plant traditional Chinese medicines with antiviral hemostatic functions on the surface and inside of the fiber, then adding plant traditional Chinese medicine antiviral hemostatic composition microcapsules in the spinning process and adsorbing the functional components in the fiber by using plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent in the scouring process, so that the antiviral hemostatic functions of the prepared viscose fiber are enhanced, then adding pore-forming agent in the spinning solution for the prepared fiber, then performing gas decomposition and loss in the forming process, so that the surface and inside of the fiber contain a large number of holes, so that the adsorption amount of the subsequent plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent is increased, then drying by microwave, further permeating the functional components into the inside of the viscose fiber by using the microwave, and using the cross-linking effect of citric acid or butyl tetracarboxylic acid and a viscose fiber matrix in the drying process The loss of functional components is reduced, the content of effective components is improved, the functionality is increased, and the prepared viscose fiber has good antibacterial, antiviral and hemostatic functions.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (6)
1. A preparation method of plant traditional Chinese medicine antiviral hemostatic viscose fiber comprises the preparation of plant traditional Chinese medicine antiviral hemostatic composition microcapsule, the preparation of plant traditional Chinese medicine antiviral hemostatic modified auxiliary agent solution and the preparation of plant traditional Chinese medicine antiviral hemostatic viscose fiber, and is characterized in that: the preparation of the plant traditional Chinese medicine antiviral hemostatic composition microcapsule comprises the following steps:
the first step is as follows: preparing an emulsion of the antiviral and hemostatic composition of the Chinese herbal medicines;
the preparation method of the plant traditional Chinese medicine antiviral and hemostatic composition emulsion comprises the following specific steps:
s1: firstly, adding an emulsifier into distilled water, and mixing for 30-50 min at a stirring speed of 800-1200 r/min and a temperature of 20-30 ℃ to obtain an emulsifier solution with a mass fraction of 1.8% -3.0%; the emulsifier is one of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate and polystyrene-maleic anhydride sodium salt;
S2: then respectively and uniformly mixing the capsule core material oily plant antiviral and hemostatic composition and the capsule wall material at the temperature of 20-30 ℃ and the stirring speed of 800-1200 r/min to respectively form a uniform capsule core material mixture and a uniform capsule wall material mixture; the capsule core material is an oily plant antiviral and hemostatic composition, and is an oily composition prepared from honeysuckle extract, sealwort extract and scutellaria extract, wherein the mass ratio of the honeysuckle extract to the polygonatum extract to the scutellaria extract is 1: 1-2: 1-2; the capsule wall material is a mixture of isophorone diisocyanate and polyaspartic acid ester, and the mass ratio of the materials is 1: 1-3; the mass ratio of the capsule core material to the capsule wall material is 1-2: 1;
s3: adding the prepared capsule core material mixture into the capsule wall material mixture, and continuously mixing for 25-35 min at the same temperature and stirring speed to form a uniform capsule core-capsule wall material mixture;
s4: then adding the prepared capsule core-capsule wall material mixture into a prepared emulsifier solution, and carrying out high-speed shearing, emulsifying and dispersing at the temperature of 30-38 ℃ and the rotating speed of 2500-2850 r/min until the particle size D90 of the emulsion is less than or equal to 1.952 μm to obtain the plant traditional Chinese medicine antiviral and hemostatic composition emulsion, wherein the mass fraction of the capsule core-capsule wall material in the emulsion is 35-50%;
The second step is that: preparing plant Chinese medicinal antivirus hemostatic composition microcapsule;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic composition microcapsule comprises the following specific steps:
s1: firstly, gradually raising the temperature of the prepared finished product plant traditional Chinese medicine antiviral and hemostatic composition emulsion to 85-92 ℃, and continuously reacting for 3.5-4.5 hours at a stirring speed of 300-600 r/min to obtain microcapsules taking the oily plant traditional Chinese medicine antiviral and hemostatic composition as capsule cores, wherein the particle size D90 is less than or equal to 2.156 microns;
s2: then defoaming to obtain the finished product plant traditional Chinese medicine antiviral hemostatic composition microcapsule, and storing for later use.
2. The preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber according to claim 1, which is characterized in that: the preparation of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following steps:
the first step is as follows: the composition of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent;
the antiviral hemostatic modifying auxiliary agent for the plant traditional Chinese medicines comprises the following components in parts by weight: honeysuckle extract, forsythia extract, isatis root extract, scutellaria extract, phyllostachys pubescens extract, polygonum cuspidatum extract and polygonatum sibiricum extract; the plant traditional Chinese medicine is prepared by the existing method or obtained by purchasing, and the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent comprises the following components in parts by weight: 15-20 parts of honeysuckle extract, 15-20 parts of fructus forsythiae extract, 20-25 parts of radix isatidis extract, 10-15 parts of scutellaria baicalensis extract, 25-30 parts of phyllostachys pubescens extract, 5-10 parts of polygonum cuspidatum extract and 10-20 parts of rhizoma polygonati extract;
The second step is that: preparing an antiviral and hemostatic modified auxiliary agent solution of the plant traditional Chinese medicine;
the preparation method of the plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution comprises the following specific steps:
s1: firstly, under the conditions that the temperature is 40-60 ℃ and the rotating speed is 200-400 r/min, the pH value of distilled water is adjusted to be 7.0-8.0, the plant traditional Chinese medicine antiviral and hemostatic modification auxiliary agent obtained by mixing is added for dissolution, the mass fraction is 15-20%, the dissolution time is 1.5-2.5 h, and the temperature is cooled to 20-25 ℃;
s2: then, the filtering area is 150-200 m2Filtering with a plate-and-frame filter, wherein the filter medium is polypropylene felt and silk, the filter pore diameter is 15-30 μm, filtering to obtain the finished plant traditional Chinese medicine antiviral hemostatic modification auxiliary agent solution, and storing for later use.
3. The preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber according to claim 1 or 2, which is characterized in that: the preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following steps:
the first step is as follows: preparing a spinning solution before spinning viscose fibers;
the preparation method of the viscose fiber pre-spinning solution comprises the following specific steps:
s1: firstly, cellulose pulp is taken as a raw material, a viscose fiber spinning solution is prepared by a conventional viscose preparation process, and the viscose fiber spinning solution comprises the following components: type A cellulose: 8.92-9.10%, sodium hydroxide: 5.50% -5.65%, and pore-forming agent is added into the viscose fiber spinning dope; the pore-forming agent is prepared by mixing one of sodium carbonate or sodium bicarbonate with polyvinyl alcohol with the average polymerization degree of 200-600, wherein the addition amount of the sodium carbonate or the sodium bicarbonate is 3.5-5.5% of the content of alpha cellulose in the viscose spinning dope, the addition amount of the polyvinyl alcohol is 5.0-10.0% of the content of the alpha cellulose in the viscose spinning dope, and the pore-forming agent is uniformly mixed and defoamed for later use;
S2: then utilizing injection equipment before spinning, calculating the stored finished product plant Chinese medicinal antiviral hemostatic composition microcapsule which accounts for a certain proportion of the content of alpha cellulose in the viscose spinning solution according to effective components, adding the microcapsule into the viscose spinning solution, and preparing to obtain spinning solution before spinning; the plant traditional Chinese medicine anti-virus hemostatic composition microcapsule accounts for 10.0 to 15.0 percent of the content of alpha cellulose in the viscose by the effective component;
the second step is that: preparing the antiviral hemostatic viscose fiber of the traditional Chinese medicine of the plant;
the preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber comprises the following specific steps:
s1: firstly, spinning the blended spinning solution through an adjusted coagulating bath to obtain primary tows, and drafting the primary tows to obtain formed tows;
s2: then, the surface and the interior of the prepared functional cellulose fiber contain more holes by utilizing the action of gas generated by the pore-forming agent and the dissolution action of polyvinyl alcohol so as to facilitate the adsorption of the subsequent functional auxiliary agent;
s3: then, a mild desulfurization process, a functional additive adsorption process, an oiling process and a multi-section multi-mode drying process are utilized to further enhance the grafting and crosslinking combination of the effective components and the cellulose fiber matrix, increase the content of the effective components and improve the functionality; the functionality of the fiber is ensured from two aspects of spinning and fiber after-finishing.
4. The preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber according to claim 3, which is characterized in that: the coagulating bath comprises 90-105 g/L of sulfuric acid and 285-300 g/L of sodium sulfate, zinc sulfate is not used, and the temperature is 45-50 ℃; the desulfurization bath comprises: na (Na)2SO34.0-6.0 g/L, and the temperature is 65-85 ℃; the functional additive used in the functional additive adsorption process is prepared by blending an antiviral and hemostatic modification additive solution of traditional Chinese herbal medicine plants and citric acid or butyl tetracarboxylic acid, wherein the mass ratio of the active ingredient content of the antiviral and hemostatic modification additive solution of traditional Chinese herbal medicine plants to the citric acid or butyl tetracarboxylic acid is 1: 1-2, enhancing the adsorption effect by using the holes caused by the pore-forming agent.
5. The preparation method of the plant traditional Chinese medicine anti-virus hemostatic viscose fiber according to claim 3, which is characterized in that: the oiling process adopts an oil bath, and the oil bath comprises the following steps: 3.0-6.0 g/L, and the temperature is 45-55 ℃; the drying process comprises the following steps: microwave drying is adopted at the front drying stage, the microwave frequency is 1260-1550 MHz, the microwave drying time is 15-20 min, and the water content of the cellulose fiber after microwave drying is 15.5% -18.5%; the rear section adopts a steam drying process, and the drying temperature is as follows: and (3) drying at 95-110 ℃ for 20-30 min, wherein the water content of the fiber is 8.5% -10.5%.
6. A plant Chinese medicinal antiviral hemostatic viscose fiber prepared by the preparation method of any one of claims 1 to 5.
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