CN112726202A - Manufacturing process of medical gauze - Google Patents
Manufacturing process of medical gauze Download PDFInfo
- Publication number
- CN112726202A CN112726202A CN202011509493.3A CN202011509493A CN112726202A CN 112726202 A CN112726202 A CN 112726202A CN 202011509493 A CN202011509493 A CN 202011509493A CN 112726202 A CN112726202 A CN 112726202A
- Authority
- CN
- China
- Prior art keywords
- product
- solution
- stirring
- drying
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M13/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
- D06M13/50—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with organometallic compounds; with organic compounds containing boron, silicon, selenium or tellurium atoms
- D06M13/503—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with organometallic compounds; with organic compounds containing boron, silicon, selenium or tellurium atoms without bond between a carbon atom and a metal or a boron, silicon, selenium or tellurium atom
-
- D—TEXTILES; PAPER
- D02—YARNS; MECHANICAL FINISHING OF YARNS OR ROPES; WARPING OR BEAMING
- D02G—CRIMPING OR CURLING FIBRES, FILAMENTS, THREADS, OR YARNS; YARNS OR THREADS
- D02G3/00—Yarns or threads, e.g. fancy yarns; Processes or apparatus for the production thereof, not otherwise provided for
- D02G3/02—Yarns or threads characterised by the material or by the materials from which they are made
- D02G3/04—Blended or other yarns or threads containing components made from different materials
-
- D—TEXTILES; PAPER
- D03—WEAVING
- D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
- D03D1/00—Woven fabrics designed to make specified articles
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M11/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereof; Such treatment combined with mechanical treatment, e.g. mercerising
- D06M11/58—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereof; Such treatment combined with mechanical treatment, e.g. mercerising with nitrogen or compounds thereof, e.g. with nitrides
- D06M11/64—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereof; Such treatment combined with mechanical treatment, e.g. mercerising with nitrogen or compounds thereof, e.g. with nitrides with nitrogen oxides; with oxyacids of nitrogen or their salts
- D06M11/65—Salts of oxyacids of nitrogen
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M11/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereof; Such treatment combined with mechanical treatment, e.g. mercerising
- D06M11/77—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereof; Such treatment combined with mechanical treatment, e.g. mercerising with silicon or compounds thereof
- D06M11/79—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereof; Such treatment combined with mechanical treatment, e.g. mercerising with silicon or compounds thereof with silicon dioxide, silicic acids or their salts
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
- D06M15/01—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment with natural macromolecular compounds or derivatives thereof
- D06M15/03—Polysaccharides or derivatives thereof
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
- D06M15/19—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment with synthetic macromolecular compounds
- D06M15/21—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
- D06M15/356—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds of other unsaturated compounds containing nitrogen, sulfur, silicon or phosphorus atoms
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M16/00—Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M2101/00—Chemical constitution of the fibres, threads, yarns, fabrics or fibrous goods made from such materials, to be treated
- D06M2101/02—Natural fibres, other than mineral fibres
- D06M2101/04—Vegetal fibres
- D06M2101/06—Vegetal fibres cellulosic
-
- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2201/00—Cellulose-based fibres, e.g. vegetable fibres
- D10B2201/01—Natural vegetable fibres
- D10B2201/02—Cotton
-
- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2201/00—Cellulose-based fibres, e.g. vegetable fibres
- D10B2201/01—Natural vegetable fibres
- D10B2201/10—Bamboo
Landscapes
- Engineering & Computer Science (AREA)
- Textile Engineering (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Microbiology (AREA)
- Mechanical Engineering (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Abstract
The invention discloses a medical gauze manufacturing process, which comprises the steps of uniformly mixing modified cotton fibers and modified bamboo fibers, then carrying out cotton carding, combing, drawing, roving spinning, spun yarn spinning, spooling, doubling and double twisting according to the traditional textile process to obtain mixed spun yarns, spinning the mixed spun yarns to form gauze gray fabric, adding an antibacterial agent into deionized water, uniformly stirring, dispersing to form antibacterial liquid, uniformly spraying the antibacterial liquid onto the gauze gray fabric, and then drying by a dryer to obtain the medical gauze; the medical gauze uses the modified cotton fiber and the modified bamboo fiber as main raw materials, the modified cotton fiber and the modified bamboo fiber have excellent antibacterial performance after modification, then the modified cotton fiber and the modified bamboo fiber are mixed and woven to form the gauze gray cloth, then the antibacterial performance of the antibacterial liquid is endowed to the gauze gray cloth by spraying the antibacterial liquid on the gauze gray cloth, and therefore the good antibacterial performance of the medical gauze is further improved.
Description
Technical Field
The invention relates to the field of medical treatment, in particular to a manufacturing process of medical gauze.
Background
The medical gauze is woven by plain weave of medium and coarse cotton yarns, has good moisture absorption and dispersion performance after bleaching and degreasing, is sterilized strictly at high temperature and high pressure, and is suitable for being used as a base material for medical bandaging, dressing and the like.
With the progress of wound healing research, it is recognized that the purpose of using a dressing is far beyond just to cover the wound surface, and the dressing must also be able to promote wound healing. When skin is damaged due to factors such as injury or diseases, moisture, electrolytes and proteins of the wound surface are lost frequently, the open wound surface also increases the probability of infection, and the wound surface is effectively closed early, so that the complications can be reduced.
The conventional medical gauze has insufficient antibacterial and bacteriostatic effects, and the probability of wound infection is easily increased, so that the key point of the invention is to provide the medical gauze with good antibacterial and bacteriostatic effects.
Disclosure of Invention
In order to overcome the technical problems, the invention aims to provide a process for manufacturing medical gauze, which comprises the following steps: the medical gauze is obtained by uniformly mixing modified cotton fibers and modified bamboo fibers, then carding, combing, drawing, roving spinning, spun yarn spinning, spooling, doubling and double twisting according to the traditional spinning process to obtain mixed spun yarns, spinning the mixed spun yarns to form gauze gray fabric, adding an antibacterial agent into deionized water, uniformly stirring, dispersing to form an antibacterial solution, uniformly spraying the antibacterial solution onto the gauze gray fabric, and then drying by a dryer, so that the problems that the antibacterial effect of the existing medical gauze is not good enough and the probability of wound infection is easily increased are solved.
The purpose of the invention can be realized by the following technical scheme:
a manufacturing process of medical gauze comprises the following steps:
the method comprises the following steps: weighing 60-80 parts of modified cotton fiber, 30-40 parts of modified bamboo fiber, 2-3 parts of antibacterial agent and 50-70 parts of deionized water according to parts by weight for later use;
step two: uniformly mixing modified cotton fibers and modified bamboo fibers, and then carrying out cotton carding, combing, drawing, roving spinning, spun yarn spinning, spooling, doubling and double twisting according to the traditional spinning process to obtain mixed spun yarns;
step three: spinning the mixed spun yarn to form gauze grey cloth;
step four: adding the antibacterial agent into deionized water, uniformly stirring at the rotating speed of 300-500r/min, and dispersing to form an antibacterial liquid;
step five: and uniformly spraying the antibacterial solution on the gauze grey cloth, and then drying for 20-30min by a dryer at the temperature of 110-130 ℃ to obtain the medical gauze.
The preparation method of the modified cotton fiber comprises the following steps:
s21: dissolving copper sulfate in deionized water, stirring for 10-20min under the condition of the rotating speed of 50-100r/min until the copper sulfate is completely dissolved to obtain a copper sulfate solution, adding sodium hydroxide into the copper sulfate solution, continuously stirring for reacting for 20-30min, carrying out vacuum filtration on a reaction system, removing filtrate, washing a filter cake for 3-5 times by using distilled water to obtain a product A, wherein the product A is copper hydroxide;
s22: adding the product A into ammonia water with the mass fraction of 25%, and completely dissolving the product A under the condition of the rotating speed of 200-300r/min to obtain a copper ammonia solution;
s23: uniformly mixing a citric acid solution and a sodium phosphite solution in equal volume to obtain a soaking solution, soaking cotton fibers in the soaking solution for 5-10min, taking out the soaked cotton fibers, placing the cotton fibers in an oven, drying at 80-90 ℃ for 5-10min, heating the oven to 150-170 ℃, continuing to dry for 2-3min, taking out the dried cotton fibers, washing with distilled water for 3-5 times, placing in the oven again, and drying at 80-90 ℃ until the temperature is reduced to obtain a product B, wherein the product B is the cotton fibers treated by citric acid;
s24: and (3) soaking the product B in a copper ammonia solution for 10-20min, taking out the soaked product B, washing the soaked product B with distilled water for 3-5 times, then placing the product B in a drying oven, and drying the product B at the temperature of 80-90 ℃ to obtain the modified cotton fiber.
The dosage ratio of the copper sulfate, the deionized water, the sodium hydroxide and the ammonia water is 0.1mol:500 mL: 0.2 mol: 250 mL; the citric acid solution accounts for 12% by mass, and the sodium phosphite solution accounts for 14% by mass.
The preparation method of the modified bamboo fiber comprises the following steps:
s41: adding chitosan with deacetylation degree of 85% into chloroacetic acid, stirring and reacting for 4-6h under the condition that the rotation speed is 200-400r/min, adjusting the pH value of a sodium carbonate solution with the mass concentration of 1-10mol/L added into a reaction system to be neutral, performing centrifugal separation, adding 3 times volume of ethanol into a supernatant, performing vacuum filtration, washing a filter cake for 2-3 times by using ethanol, and performing freeze drying to obtain a product C, wherein the product C is N, O-carboxymethyl chitosan powder;
s42: uniformly mixing sodium hydroxide, thiourea, urea and deionized water to obtain a mixed solution, adding the bamboo fiber into the mixed solution, then adding the product C, stirring for 20-40min at the rotation speed of 2000-4000r/min, then carrying out vacuum filtration, washing the filter cake with distilled water for 3-5 times, then placing in an oven, and drying at the temperature of 50-70 ℃ to obtain the modified bamboo fiber.
In the step S41, the mass ratio of the chitosan to the chloroacetic acid is 1: 4-5; in the step S42, the mass ratio of the sodium hydroxide to the thiourea to the urea to the deionized water is 16:13:16: 150; the mass ratio of the product C to the bamboo fibers is 1-7: 100.
The preparation method of the antibacterial agent comprises the following steps:
s61: adding polyvinylpyrrolidone into a three-neck flask provided with a stirrer and a thermometer, adding ethylene glycol, moving the three-neck flask into an oil bath at the temperature of 80 ℃, and stirring at the rotation speed of 400-600r/min until the polyvinylpyrrolidone is completely dissolved in the ethylene glycol to obtain a product D;
s62: adding silver nitrate solid into the product D, continuously stirring until the silver nitrate solid is completely dissolved, then heating to 110-120 ℃, continuously reacting for 1-2h, naturally cooling, adding acetone, uniformly stirring at the rotation speed of 50-100r/min, centrifugally separating, washing the lower-layer precipitate for 1-2 times by using ethanol to obtain a product E, wherein the product E is a nano-silver colloid;
s63: adding the product E into toluene, performing ultrasonic dispersion until the product E is uniformly dispersed to obtain a dispersion liquid a, adding the dispersion liquid a into a three-neck flask provided with a stirrer and a thermometer, dropwise adding tetraethoxysilane and triethylamine under stirring at the rotation speed of 300-400r/min, controlling the dropwise adding time to be 5-10min, continuously stirring for 20-30h at room temperature, performing centrifugal separation, washing the lower-layer precipitate for 3-5 times by using ethanol and distilled water respectively, then placing the lower-layer precipitate into an oven, drying at the temperature of 50-70 ℃, and crushing to obtain a product F, wherein the product F is powder formed by coating nano silver with silicon dioxide;
s64: uniformly mixing 0.1mol/L trihydroxymethyl aminomethane solution and 0.1mol/L hydrochloric acid, adding deionized water to adjust the pH value to 8.2 to obtain a buffer solution, adding a product F into the buffer solution, performing ultrasonic dispersion until the product F is uniformly dispersed to obtain a dispersion liquid b, adding the dispersion liquid b into a three-neck flask provided with a stirrer and a thermometer, dropping ethyl orthosilicate and 3- (methacryloyl) propyl trimethoxy silane while stirring at the rotation speed of 300-400r/min, controlling the dropping time to be 5-10min, stirring at room temperature for 14-18 hr, centrifuging, washing the lower precipitate with ethanol and distilled water for 3-5 times, placing the lower precipitate in oven, drying at 50-70 deg.C, and pulverizing to obtain antibacterial agent.
In the preparation process of the product E, the dosage ratio of the polyvinylpyrrolidone, the glycol, the silver nitrate solid and the acetone is 100 g: 750 mL: 4 g: 200g of the total weight of the mixture; in the step S63, the dosage ratio of the product E, the toluene, the ethyl orthosilicate and the triethylamine is 0.4 g: 100mL of: 3mL of: 3 mL; the volume ratio of the tris solution to hydrochloric acid in step S64 is 5: 2-3; the dosage ratio of the product F, the buffer solution, the ethyl orthosilicate and the 3- (methacryloyl) propyl trimethoxy silane is 0.2 g: 400 mL: 1mL:1 mL.
The invention has the beneficial effects that:
the medical gauze manufacturing process comprises the steps of uniformly mixing modified cotton fibers and modified bamboo fibers, then carrying out cotton carding, combing, drawing, roving spinning, spun yarn spinning, spooling, doubling and two-for-one twisting according to the traditional textile process to obtain mixed spun yarns, spinning the mixed spun yarns to form gauze gray fabrics, adding an antibacterial agent into deionized water, uniformly stirring, dispersing to form an antibacterial solution, uniformly spraying the antibacterial solution onto the gauze gray fabrics, and then drying by a dryer to obtain the medical gauze; the medical gauze uses the modified cotton fiber and the modified bamboo fiber as main raw materials, the modified cotton fiber and the modified bamboo fiber have excellent antibacterial performance after modification, then the modified cotton fiber and the modified bamboo fiber are mixed and woven to form the gauze gray cloth, then the antibacterial performance of the antibacterial liquid is endowed to the gauze gray cloth by spraying the antibacterial liquid on the gauze gray cloth, and therefore the good antibacterial performance of the medical gauze is further improved.
The invention prepares a modified cotton fiber in the process of preparing medical gauze, which is modified by citric acid and cuprammonium solution, wherein the citric acid is a natural preservative and antioxidant, has the effect of inhibiting bacteria, and is also an excellent metal complexing agent, the copper ion is a metal ion with good antibacterial property, and the copper ion is a trace element of human body, forms a plurality of enzymes and bioactive proteins in human body, participates in substance and energy metabolism, has high safety, after the cotton fiber is treated by the citric acid, the citric acid and the cotton fiber are in cross-linking action, then the cuprammonium solution treats the citric acid cross-linked cotton fiber, so that the copper in the cuprammonium ion and the oxygen in the hydroxyl group of the citric acid cross-linked cotton fiber and the oxygen connected with the carbonyl group in the ester group are in coordination and complexation, thereby forming a chelate, and the copper ions are tightly connected on the cotton fiber, endowing the cotton fiber with the antibacterial effect of copper ions;
the invention also prepares a modified bamboo fiber in the process of preparing medical gauze, the bamboo fiber is a natural antibacterial fiber, the chitosan has good bioactivity, biocompatibility, biodegradability and special functions of antibiosis, anticorrosion, hemostasis, wound healing promotion and the like, the bamboo fiber is modified by using the chitosan, partial hydroxyl and amino on the molecular chain of the chitosan are replaced by carboxymethyl through the reaction of the chitosan and chloroacetic acid, N, O-carboxymethyl chitosan is obtained, the N, O-carboxymethyl chitosan has inhibition effect on common bacteria, the N, O-carboxymethyl chitosan permeates into the cell body, adsorbs cytoplasm with charges in the cell body, generates flocculation, disturbs the normal physiological activity of the cell, or blocks the transcription of DNA in the cell body so as to inhibit the propagation of the bacteria, the bamboo fiber is treated by the N, O-carboxymethyl chitosan, so that the bamboo fiber is endowed with the antibacterial and bacteriostatic effects of the N, O-carboxymethyl chitosan, and the antibacterial performance of the bamboo fiber is further improved;
the invention also prepares an antibacterial agent in the process of preparing the medical gauze, the antibacterial agent is prepared by firstly preparing nano silver colloid, the silver ion is a metal ion with high activity and bacteriostasis and sterilization, has small toxic action on human body, but because the activity is high and the stability is poor, the product is easy to be oxidized to turn black and increase the toxicity, silicon dioxide is wrapped on the surface of the nano-silver colloid by a sol-gel method to form powder formed by coating the nano-silver with the silicon dioxide, then the surface of the powder formed by coating the nano-silver with the silicon dioxide is modified by hydrophobic groups to prepare the lipophilic powder formed by coating the nano-silver with the silicon dioxide, so that the silver ions are wrapped, the prepared antibacterial agent has the sterilization and antibacterial effects of the original silver ions, meanwhile, the oxidation of silver ions is limited, so that the antibacterial effect of the antibacterial agent is good, and the toxicity is further reduced.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
the embodiment is a manufacturing process of medical gauze, which comprises the following steps:
the method comprises the following steps: weighing 60 parts of modified cotton fiber, 30 parts of modified bamboo fiber, 2 parts of antibacterial agent and 50 parts of deionized water according to parts by weight for later use;
step two: uniformly mixing modified cotton fibers and modified bamboo fibers, and then carrying out cotton carding, combing, drawing, roving spinning, spun yarn spinning, spooling, doubling and double twisting according to the traditional spinning process to obtain mixed spun yarns;
step three: spinning the mixed spun yarn to form gauze grey cloth;
step four: adding the antibacterial agent into deionized water, uniformly stirring at the rotating speed of 300r/min, and dispersing to form an antibacterial liquid;
step five: and uniformly spraying the antibacterial solution on the gauze grey cloth, and then drying for 20min by a dryer at the temperature of 110 ℃ to obtain the medical gauze.
The preparation method of the modified cotton fiber comprises the following steps:
s21: dissolving copper sulfate in deionized water, stirring for 10min at the rotation speed of 50r/min until the copper sulfate is completely dissolved to obtain a copper sulfate solution, adding sodium hydroxide into the copper sulfate solution, continuously stirring for reaction for 20min, carrying out vacuum filtration on a reaction system, removing filtrate, and cleaning a filter cake for 3 times by using distilled water to obtain a product A;
s22: adding the product A into ammonia water with the mass fraction of 25%, and completely dissolving the product A under the condition of the rotating speed of 200r/min to obtain a copper ammonia solution;
s23: uniformly mixing a citric acid solution and a sodium phosphite solution in equal volume to obtain a soaking solution, soaking cotton fibers in the soaking solution for 5min, taking out the soaked cotton fibers, placing the cotton fibers in an oven, drying for 5min at the temperature of 80 ℃, heating the oven to 150 ℃, continuing to dry for 2min, taking out the dried cotton fibers, washing for 3 times by using distilled water, placing the cotton fibers in the oven again, and drying at the temperature of 80 ℃ to obtain a product B;
s24: and (3) soaking the product B in a copper ammonia solution for 10min, taking out the soaked product B, washing the soaked product B with distilled water for 3 times, then placing the product B in an oven, and drying the product B at the temperature of 80 ℃ to obtain the modified cotton fiber.
The dosage ratio of the copper sulfate, the deionized water, the sodium hydroxide and the ammonia water is 0.1mol:500 mL: 0.2 mol: 250 mL; the citric acid solution accounts for 12% by mass, and the sodium phosphite solution accounts for 14% by mass.
The preparation method of the modified bamboo fiber comprises the following steps:
s41: adding chitosan with deacetylation degree of 85% into chloroacetic acid, stirring and reacting for 4h at the rotation speed of 200r/min, adjusting the pH of a sodium carbonate solution with the amount concentration of 1mol/L added into a reaction system to be neutral, performing centrifugal separation, adding 3 times volume of ethanol into supernatant, performing vacuum filtration, washing a filter cake for 2 times by using ethanol, and performing freeze drying to obtain a product C;
s42: uniformly mixing sodium hydroxide, thiourea, urea and deionized water to obtain a mixed solution, adding the bamboo fiber into the mixed solution, adding the product C, stirring for 20min at the rotation speed of 2000r/min, carrying out vacuum filtration, washing the filter cake for 3 times by using distilled water, placing the filter cake into an oven, and drying at the temperature of 50 ℃ to obtain the modified bamboo fiber.
In the step S41, the mass ratio of the chitosan to the chloroacetic acid is 1: 4; in the step S42, the mass ratio of the sodium hydroxide to the thiourea to the urea to the deionized water is 16:13:16: 150; the mass ratio of the product C to the bamboo fibers is 1: 100.
The preparation method of the antibacterial agent comprises the following steps:
s61: adding polyvinylpyrrolidone into a three-neck flask provided with a stirrer and a thermometer, adding ethylene glycol, moving the three-neck flask into an oil bath at the temperature of 80 ℃, and stirring at the rotation speed of 400r/min until the polyvinylpyrrolidone is completely dissolved in the ethylene glycol to obtain a product D;
s62: adding silver nitrate solid into the product D, continuously stirring until the silver nitrate solid is completely dissolved, then heating to 110 ℃, continuously reacting for 1-2h, naturally cooling, adding acetone, uniformly stirring at the rotation speed of 50r/min, centrifugally separating, and washing the lower-layer precipitate for 1 time by using ethanol to obtain a product E;
s63: adding the product E into toluene, performing ultrasonic dispersion until the product E is uniformly dispersed to obtain a dispersion liquid a, adding the dispersion liquid a into a three-neck flask provided with a stirrer and a thermometer, dropwise adding tetraethoxysilane and triethylamine under stirring at the rotation speed of 300r/min, controlling the dropwise adding time to be 5min, continuously stirring for 20h at room temperature, performing centrifugal separation, washing the lower-layer precipitate for 3 times by using ethanol and distilled water respectively, then placing the lower-layer precipitate into a drying oven, drying at the temperature of 50 ℃, and crushing to obtain a product F;
s64: uniformly mixing 0.1mol/L trihydroxymethyl aminomethane solution and 0.1mol/L hydrochloric acid, adding deionized water to adjust the pH value to 8.2 to obtain a buffer solution, adding a product F into the buffer solution, performing ultrasonic dispersion until the product F is uniformly dispersed to obtain a dispersion solution b, adding the dispersion solution b into a three-neck flask provided with a stirrer and a thermometer, dropwise adding tetraethoxysilane and 3- (methacryloyl) propyl trimethoxysilane under stirring at the rotation speed of 300r/min, controlling the dropwise adding time to be 5min, continuously stirring for 14h at room temperature, performing centrifugal separation, washing the lower-layer precipitate for 3 times by using ethanol and distilled water respectively, then placing the lower-layer precipitate into an oven, drying at the temperature of 50 ℃, and crushing to obtain the antibacterial agent.
In the preparation process of the product E, the dosage ratio of the polyvinylpyrrolidone, the glycol, the silver nitrate solid and the acetone is 100 g: 750 mL: 4 g: 200g of the total weight of the mixture; in the step S63, the dosage ratio of the product E, the toluene, the ethyl orthosilicate and the triethylamine is 0.4 g: 100mL of: 3mL of: 3 mL; the volume ratio of the tris solution to hydrochloric acid in step S64 is 5: 2; the dosage ratio of the product F, the buffer solution, the ethyl orthosilicate and the 3- (methacryloyl) propyl trimethoxy silane is 0.2 g: 400 mL: 1mL:1 mL.
Example 2:
the embodiment is a manufacturing process of medical gauze, which comprises the following steps:
the method comprises the following steps: weighing 70 parts of modified cotton fiber, 35 parts of modified bamboo fiber, 3 parts of antibacterial agent and 60 parts of deionized water according to parts by weight for later use;
step two: uniformly mixing modified cotton fibers and modified bamboo fibers, and then carrying out cotton carding, combing, drawing, roving spinning, spun yarn spinning, spooling, doubling and double twisting according to the traditional spinning process to obtain mixed spun yarns;
step three: spinning the mixed spun yarn to form gauze grey cloth;
step four: adding the antibacterial agent into deionized water, uniformly stirring at the rotating speed of 400r/min, and dispersing to form an antibacterial liquid;
step five: and uniformly spraying the antibacterial solution on the gauze grey cloth, and then drying for 25min by a dryer at the temperature of 120 ℃ to obtain the medical gauze.
The preparation method of the modified cotton fiber comprises the following steps:
s21: dissolving copper sulfate in deionized water, stirring for 15min under the condition of the rotating speed of 75r/min until the copper sulfate is completely dissolved to obtain a copper sulfate solution, adding sodium hydroxide into the copper sulfate solution, continuously stirring for reaction for 25min, carrying out vacuum filtration on a reaction system, removing filtrate, and cleaning a filter cake for 4 times by using distilled water to obtain a product A;
s22: adding the product A into ammonia water with the mass fraction of 25%, and completely dissolving the product A under the condition of the rotating speed of 250r/min to obtain a copper ammonia solution;
s23: uniformly mixing a citric acid solution and a sodium phosphite solution in equal volume to obtain a soaking solution, soaking cotton fibers in the soaking solution for 7min, taking out the soaked cotton fibers, placing the cotton fibers in an oven, drying at 85 ℃ for 7min, heating the oven to 160 ℃, continuing to dry for 3in, taking out the dried cotton fibers, washing for 4 times with distilled water, placing the cotton fibers in the oven again, and drying at 85 ℃ to obtain a product B;
s24: and (3) soaking the product B in a copper ammonia solution for 15min, taking out the soaked product B, washing the soaked product B with distilled water for 4 times, then placing the product B in an oven, and drying the product B at the temperature of 85 ℃ to obtain the modified cotton fiber.
The dosage ratio of the copper sulfate, the deionized water, the sodium hydroxide and the ammonia water is 0.1mol:500 mL: 0.2 mol: 250 mL; the citric acid solution accounts for 12% by mass, and the sodium phosphite solution accounts for 14% by mass.
The preparation method of the modified bamboo fiber comprises the following steps:
s41: adding chitosan with deacetylation degree of 85% into chloroacetic acid, stirring and reacting for 5h at the rotation speed of 300r/min, adjusting the pH of a sodium carbonate solution with the substance addition concentration of 5mol/L in a reaction system to be neutral, performing centrifugal separation, adding 3 times volume of ethanol into supernatant, performing vacuum filtration, washing a filter cake for 3 times with ethanol, and performing freeze drying to obtain a product C;
s42: uniformly mixing sodium hydroxide, thiourea, urea and deionized water to obtain a mixed solution, adding bamboo fibers into the mixed solution, adding a product C, stirring for 30min at the rotation speed of 3000r/min, carrying out vacuum filtration, washing a filter cake for 3-5 times by using distilled water, placing the filter cake in a drying oven, and drying at the temperature of 60 ℃ to obtain the modified bamboo fibers.
In the step S41, the mass ratio of the chitosan to the chloroacetic acid is 1: 4; in the step S42, the mass ratio of the sodium hydroxide to the thiourea to the urea to the deionized water is 16:13:16: 150; the mass ratio of the product C to the bamboo fibers is 3: 100.
The preparation method of the antibacterial agent comprises the following steps:
s61: adding polyvinylpyrrolidone into a three-neck flask provided with a stirrer and a thermometer, adding ethylene glycol, moving the three-neck flask into an oil bath at the temperature of 80 ℃, and stirring at the rotation speed of 500r/min until the polyvinylpyrrolidone is completely dissolved in the ethylene glycol to obtain a product D;
s62: adding silver nitrate solid into the product D, continuously stirring until the silver nitrate solid is completely dissolved, then heating to 115 ℃ to continue reacting for 2h, naturally cooling, adding acetone, uniformly stirring at the rotation speed of 75r/min, centrifugally separating, and washing the lower-layer precipitate for 2 times by using ethanol to obtain a product E;
s63: adding the product E into toluene, performing ultrasonic dispersion until the product E is uniformly dispersed to obtain a dispersion liquid a, adding the dispersion liquid a into a three-neck flask provided with a stirrer and a thermometer, dropwise adding tetraethoxysilane and triethylamine under stirring at the rotation speed of 350r/min, controlling the dropwise adding time to be 7min, continuously stirring for 25h at room temperature, performing centrifugal separation, washing the lower-layer precipitate for 3-5 times by using ethanol and distilled water respectively, then placing the lower-layer precipitate into an oven, drying at the temperature of 60 ℃, and crushing to obtain a product F;
s64: uniformly mixing 0.1mol/L trihydroxymethyl aminomethane solution and 0.1mol/L hydrochloric acid, adding deionized water to adjust the pH value to 8.2 to obtain a buffer solution, adding a product F into the buffer solution, performing ultrasonic dispersion until the product F is uniformly dispersed to obtain a dispersion solution b, adding the dispersion solution b into a three-neck flask provided with a stirrer and a thermometer, dropwise adding tetraethoxysilane and 3- (methacryloyl) propyl trimethoxysilane under stirring at the rotation speed of 350r/min, controlling the dropwise adding time to be 7min, continuously stirring for 16h at room temperature, performing centrifugal separation, washing the lower-layer precipitate for 4 times by using ethanol and distilled water respectively, then placing the lower-layer precipitate into an oven, drying at the temperature of 60 ℃, and crushing to obtain the antibacterial agent.
In the preparation process of the product E, the dosage ratio of the polyvinylpyrrolidone, the glycol, the silver nitrate solid and the acetone is 100 g: 750 mL: 4 g: 200g of the total weight of the mixture; in the step S63, the dosage ratio of the product E, the toluene, the ethyl orthosilicate and the triethylamine is 0.4 g: 100mL of: 3mL of: 3 mL; the volume ratio of the tris solution to hydrochloric acid in step S64 is 5: 2; the dosage ratio of the product F, the buffer solution, the ethyl orthosilicate and the 3- (methacryloyl) propyl trimethoxy silane is 0.2 g: 400 mL: 1mL:1 mL.
Example 3:
the embodiment is a manufacturing process of medical gauze, which comprises the following steps:
the method comprises the following steps: weighing 80 parts of modified cotton fiber, 40 parts of modified bamboo fiber, 3 parts of antibacterial agent and 70 parts of deionized water according to parts by weight for later use;
step two: uniformly mixing modified cotton fibers and modified bamboo fibers, and then carrying out cotton carding, combing, drawing, roving spinning, spun yarn spinning, spooling, doubling and double twisting according to the traditional spinning process to obtain mixed spun yarns;
step three: spinning the mixed spun yarn to form gauze grey cloth;
step four: adding the antibacterial agent into deionized water, uniformly stirring at the rotating speed of 500r/min, and dispersing to form an antibacterial liquid;
step five: and uniformly spraying the antibacterial solution on the gauze grey cloth, and then drying for 30min by a dryer at the temperature of 130 ℃ to obtain the medical gauze.
The preparation method of the modified cotton fiber comprises the following steps:
s21: dissolving copper sulfate in deionized water, stirring for 20min under the condition of the rotating speed of 100r/min until the copper sulfate is completely dissolved to obtain a copper sulfate solution, adding sodium hydroxide into the copper sulfate solution, continuously stirring for reaction for 30min, carrying out vacuum filtration on a reaction system, removing filtrate, and washing a filter cake for 5 times by using distilled water to obtain a product A;
s22: adding the product A into ammonia water with the mass fraction of 25%, and completely dissolving the product A under the condition of the rotating speed of 300r/min to obtain a copper ammonia solution;
s23: uniformly mixing a citric acid solution and a sodium phosphite solution in equal volume to obtain a soaking solution, soaking cotton fibers in the soaking solution for 10min, taking out the soaked cotton fibers, placing the cotton fibers in an oven, drying for 10min at the temperature of 90 ℃, heating the oven to 170 ℃, continuing to dry for 3min, taking out the dried cotton fibers, washing for 5 times with distilled water, placing the cotton fibers in the oven again, and drying at the temperature of 90 ℃ to obtain a product B;
s24: and (3) soaking the product B in a copper ammonia solution for 20min, taking out the soaked product B, washing the soaked product B with distilled water for 5 times, then placing the product B in an oven, and drying the product B at the temperature of 90 ℃ to obtain the modified cotton fiber.
The dosage ratio of the copper sulfate, the deionized water, the sodium hydroxide and the ammonia water is 0.1mol:500 mL: 0.2 mol: 250 mL; the citric acid solution accounts for 12% by mass, and the sodium phosphite solution accounts for 14% by mass.
The preparation method of the modified bamboo fiber comprises the following steps:
s41: adding chitosan with deacetylation degree of 85% into chloroacetic acid, stirring and reacting for 6h at the rotation speed of 400r/min, adjusting the pH of a sodium carbonate solution with the substance addition concentration of 10mol/L in a reaction system to be neutral, performing centrifugal separation, adding 3 times volume of ethanol into supernatant, performing vacuum filtration, washing a filter cake for 3 times with ethanol, and performing freeze drying to obtain a product C;
s42: uniformly mixing sodium hydroxide, thiourea, urea and deionized water to obtain a mixed solution, adding the bamboo fiber into the mixed solution, adding the product C, stirring for 40min at the rotation speed of 4000r/min, carrying out vacuum filtration, washing the filter cake for 5 times by using distilled water, placing the filter cake in an oven, and drying at the temperature of 70 ℃ to obtain the modified bamboo fiber.
In the step S41, the mass ratio of the chitosan to the chloroacetic acid is 1: 5; in the step S42, the mass ratio of the sodium hydroxide to the thiourea to the urea to the deionized water is 16:13:16: 150; the mass ratio of the product C to the bamboo fibers is 7: 100.
The preparation method of the antibacterial agent comprises the following steps:
s61: adding polyvinylpyrrolidone into a three-neck flask provided with a stirrer and a thermometer, adding ethylene glycol, moving the three-neck flask into an oil bath at the temperature of 80 ℃, and stirring at the rotation speed of 600r/min until the polyvinylpyrrolidone is completely dissolved in the ethylene glycol to obtain a product D;
s62: adding silver nitrate solid into the product D, continuously stirring until the silver nitrate solid is completely dissolved, then heating to 120 ℃ to continue reacting for 2h, naturally cooling, adding acetone, uniformly stirring at the rotation speed of 100r/min, centrifugally separating, and washing the lower-layer precipitate for 2 times by using ethanol to obtain a product E;
s63: adding the product E into toluene, performing ultrasonic dispersion until the product E is uniformly dispersed to obtain a dispersion liquid a, adding the dispersion liquid a into a three-neck flask provided with a stirrer and a thermometer, dropwise adding tetraethoxysilane and triethylamine while stirring at the rotation speed of 400r/min, controlling the dropwise adding time to be 10min, continuously stirring for 30h at room temperature, performing centrifugal separation, washing the lower-layer precipitate for 5 times by using ethanol and distilled water respectively, then placing the lower-layer precipitate into a drying oven, drying at the temperature of 70 ℃, and crushing to obtain a product F;
s64: uniformly mixing 0.1mol/L trihydroxymethyl aminomethane solution and 0.1mol/L hydrochloric acid, adding deionized water to adjust the pH value to 8.2 to obtain a buffer solution, adding a product F into the buffer solution, performing ultrasonic dispersion until the product F is uniformly dispersed to obtain a dispersion solution b, adding the dispersion solution b into a three-neck flask provided with a stirrer and a thermometer, dropwise adding tetraethoxysilane and 3- (methacryloyl) propyl trimethoxysilane under stirring at the rotation speed of 400r/min, controlling the dropwise adding time to be 10min, continuously stirring for 18h at room temperature, performing centrifugal separation, washing the lower-layer precipitate for 5 times by using ethanol and distilled water respectively, then placing the lower-layer precipitate into an oven, drying at the temperature of 70 ℃, and crushing to obtain the antibacterial agent.
In the preparation process of the product E, the dosage ratio of the polyvinylpyrrolidone, the glycol, the silver nitrate solid and the acetone is 100 g: 750 mL: 4 g: 200g of the total weight of the mixture; in the step S63, the dosage ratio of the product E, the toluene, the ethyl orthosilicate and the triethylamine is 0.4 g: 100mL of: 3mL of: 3 mL; the volume ratio of the tris solution to hydrochloric acid in step S64 is 5: 3; the dosage ratio of the product F, the buffer solution, the ethyl orthosilicate and the 3- (methacryloyl) propyl trimethoxy silane is 0.2 g: 400 mL: 1mL:1 mL.
Comparative example 1:
comparative example 1 is a medical gauze which is commonly available on the market;
comparative example 2:
comparative example 2 is medical gauze to which nano magnesium hydroxide was added as an antibacterial agent;
| sample (I) | Example 1 | Example 2 | Example 3 | Comparative example 1 | Comparative example 2 |
| Escherichia coli inhibitory rate (%) | 99.5 | 99.7 | 99.9 | 73.2 | 87.4 |
| Staphylococcus aureus inhibitory rate (%) | 99.7 | 99.8 | 99.9 | 75.1 | 86.9 |
| Candida albicans inhibitory rate (%) | 99.3 | 99.6 | 99.9 | 74.8 | 94.2 |
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing is illustrative and explanatory only and is not intended to be exhaustive or to limit the invention to the precise embodiments described, and various modifications, additions, and substitutions may be made by those skilled in the art without departing from the scope of the invention or exceeding the scope of the claims.
Claims (7)
1. A manufacturing process of medical gauze is characterized by comprising the following steps:
the method comprises the following steps: weighing 60-80 parts of modified cotton fiber, 30-40 parts of modified bamboo fiber, 2-3 parts of antibacterial agent and 50-70 parts of deionized water according to parts by weight for later use;
step two: uniformly mixing modified cotton fibers and modified bamboo fibers, and then carrying out cotton carding, combing, drawing, roving spinning, spun yarn spinning, spooling, doubling and double twisting according to the traditional spinning process to obtain mixed spun yarns;
step three: spinning the mixed spun yarn to form gauze grey cloth;
step four: adding the antibacterial agent into deionized water, uniformly stirring at the rotating speed of 300-500r/min, and dispersing to form an antibacterial liquid;
step five: and uniformly spraying the antibacterial solution on the gauze grey cloth, and then drying for 20-30min by a dryer at the temperature of 110-130 ℃ to obtain the medical gauze.
2. The process for manufacturing medical gauze according to claim 1, wherein the preparation method of the modified cotton fiber is as follows:
s21: dissolving copper sulfate in deionized water, stirring for 10-20min at the rotation speed of 50-100r/min until the copper sulfate is completely dissolved to obtain a copper sulfate solution, adding sodium hydroxide into the copper sulfate solution, continuously stirring for reaction for 20-30min, performing vacuum filtration on a reaction system, removing filtrate, and washing a filter cake for 3-5 times by using distilled water to obtain a product A;
s22: adding the product A into ammonia water with the mass fraction of 25%, and completely dissolving the product A under the condition of the rotating speed of 200-300r/min to obtain a copper ammonia solution;
s23: uniformly mixing a citric acid solution and a sodium phosphite solution in equal volume to obtain a soaking solution, soaking cotton fibers in the soaking solution for 5-10min, taking out the soaked cotton fibers, placing the cotton fibers in an oven, drying at 80-90 ℃ for 5-10min, heating the oven to 150-170 ℃, continuing to dry for 2-3min, taking out the dried cotton fibers, washing with distilled water for 3-5 times, placing in the oven again, and drying at 80-90 ℃ until the temperature is reduced to obtain a product B;
s24: and (3) soaking the product B in a copper ammonia solution for 10-20min, taking out the soaked product B, washing the soaked product B with distilled water for 3-5 times, then placing the product B in a drying oven, and drying the product B at the temperature of 80-90 ℃ to obtain the modified cotton fiber.
3. The manufacturing process of medical gauze according to claim 2, wherein the dosage ratio of the copper sulfate, the deionized water, the sodium hydroxide and the ammonia water is 0.1mol:500 mL: 0.2 mol: 250 mL; the citric acid solution accounts for 12% by mass, and the sodium phosphite solution accounts for 14% by mass.
4. The manufacturing process of medical gauze according to claim 1, wherein the preparation method of the modified bamboo fiber is as follows:
s41: adding chitosan with deacetylation degree of 85% into chloroacetic acid, stirring and reacting for 4-6h under the condition that the rotation speed is 200-400r/min, adjusting the pH value of a sodium carbonate solution with the mass concentration of 1-10mol/L added into a reaction system to be neutral, performing centrifugal separation, adding 3 times volume of ethanol into a supernatant, performing vacuum filtration, washing a filter cake for 2-3 times by using ethanol, and performing freeze drying to obtain a product C;
s42: uniformly mixing sodium hydroxide, thiourea, urea and deionized water to obtain a mixed solution, adding the bamboo fiber into the mixed solution, then adding the product C, stirring for 20-40min at the rotation speed of 2000-4000r/min, then carrying out vacuum filtration, washing the filter cake with distilled water for 3-5 times, then placing in an oven, and drying at the temperature of 50-70 ℃ to obtain the modified bamboo fiber.
5. The process for manufacturing medical gauze according to claim 4, wherein the mass ratio of the chitosan to the chloroacetic acid in the step S41 is 1: 4-5; in the step S42, the mass ratio of the sodium hydroxide to the thiourea to the urea to the deionized water is 16:13:16: 150; the mass ratio of the product C to the bamboo fibers is 1-7: 100.
6. The process for manufacturing medical gauze according to claim 1, wherein the antibacterial agent is prepared by the following steps:
s61: adding polyvinylpyrrolidone into a three-neck flask provided with a stirrer and a thermometer, adding ethylene glycol, moving the three-neck flask into an oil bath at the temperature of 80 ℃, and stirring at the rotation speed of 400-600r/min until the polyvinylpyrrolidone is completely dissolved in the ethylene glycol to obtain a product D;
s62: adding silver nitrate solid into the product D, continuously stirring until the silver nitrate solid is completely dissolved, then heating to 110-120 ℃, continuously reacting for 1-2h, naturally cooling, adding acetone, uniformly stirring at the rotation speed of 50-100r/min, centrifugally separating, and washing the lower-layer precipitate for 1-2 times by using ethanol to obtain a product E;
s63: adding the product E into toluene, performing ultrasonic dispersion until the product E is uniformly dispersed to obtain a dispersion liquid a, adding the dispersion liquid a into a three-neck flask provided with a stirrer and a thermometer, dropwise adding tetraethoxysilane and triethylamine under stirring at the rotation speed of 300-400r/min, controlling the dropwise adding time to be 5-10min, continuously stirring for 20-30h at room temperature, performing centrifugal separation, washing the lower-layer precipitate for 3-5 times by using ethanol and distilled water respectively, then placing the lower-layer precipitate into an oven, drying at the temperature of 50-70 ℃, and crushing to obtain a product F;
s64: uniformly mixing 0.1mol/L trihydroxymethyl aminomethane solution and 0.1mol/L hydrochloric acid, adding deionized water to adjust the pH value to 8.2 to obtain a buffer solution, adding a product F into the buffer solution, performing ultrasonic dispersion until the product F is uniformly dispersed to obtain a dispersion liquid b, adding the dispersion liquid b into a three-neck flask provided with a stirrer and a thermometer, dropping ethyl orthosilicate and 3- (methacryloyl) propyl trimethoxy silane while stirring at the rotation speed of 300-400r/min, controlling the dropping time to be 5-10min, stirring at room temperature for 14-18 hr, centrifuging, washing the lower precipitate with ethanol and distilled water for 3-5 times, placing the lower precipitate in oven, drying at 50-70 deg.C, and pulverizing to obtain antibacterial agent.
7. The process for manufacturing medical gauze according to claim 6, wherein the dosage ratio of the polyvinylpyrrolidone, the glycol, the silver nitrate solid and the acetone in the preparation process of the product E is 100 g: 750 mL: 4 g: 200g of the total weight of the mixture; in the step S63, the dosage ratio of the product E, the toluene, the ethyl orthosilicate and the triethylamine is 0.4 g: 100mL of: 3mL of: 3 mL; the volume ratio of the tris solution to hydrochloric acid in step S64 is 5: 2-3; the dosage ratio of the product F, the buffer solution, the ethyl orthosilicate and the 3- (methacryloyl) propyl trimethoxy silane is 0.2 g: 400 mL: 1mL:1 mL.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011509493.3A CN112726202A (en) | 2020-12-19 | 2020-12-19 | Manufacturing process of medical gauze |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011509493.3A CN112726202A (en) | 2020-12-19 | 2020-12-19 | Manufacturing process of medical gauze |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112726202A true CN112726202A (en) | 2021-04-30 |
Family
ID=75603905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011509493.3A Withdrawn CN112726202A (en) | 2020-12-19 | 2020-12-19 | Manufacturing process of medical gauze |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112726202A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116288979A (en) * | 2023-01-17 | 2023-06-23 | 武汉纺织大学 | New technology for continuous industrial production of antibacterial textile and application thereof |
-
2020
- 2020-12-19 CN CN202011509493.3A patent/CN112726202A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116288979A (en) * | 2023-01-17 | 2023-06-23 | 武汉纺织大学 | New technology for continuous industrial production of antibacterial textile and application thereof |
| CN116288979B (en) * | 2023-01-17 | 2024-04-16 | 武汉纺织大学 | New technology for continuous industrial production of antibacterial textile and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2669438C (en) | Nanosilver coated bacterial cellulose | |
| CN102727926B (en) | The preparation method of the composite wound dressing of a kind of polysaccharide and nanometer bacteria cellulose | |
| CN101905031B (en) | Method for preparing flamazine/bacterial cellulose composite wound dressing | |
| CN112210846B (en) | Preparation method of plant antibacterial, antiviral, skin-care and health-care cellulose fiber | |
| CN106192074B (en) | A kind of preparation method of the graphene oxide being loaded with nano silver particles/seaweed composite fibre | |
| CN101985779A (en) | Alga and cellulose composite fiber and manufacturing method therefor | |
| CN107869048B (en) | Functional polysaccharide antibacterial modified natural fiber and preparation method thereof | |
| CN107385597B (en) | Copper ion antibacterial nylon yarn for mesh fabric production | |
| CN105839408A (en) | Preparation method of bamboo fiber-cotton and ramie blended fabric | |
| CN110965149A (en) | Water lily protein fiber and preparation process thereof | |
| CN103638551B (en) | Preparation method for chitosan 6-OH immobilized cyclodextrin included tea tree oil thermo-sensitive hydrogel | |
| CN110373900A (en) | A kind of preparation method of chitosan oligosaccharide grafting viscose rayon | |
| CN112726202A (en) | Manufacturing process of medical gauze | |
| CN108004762B (en) | Antibacterial silk product with nano-copper and preparation method thereof | |
| CN1093189C (en) | Apocynum fibre, chitin fibre and cotton fibre blended yarn, its preparation method and application | |
| CN111349976A (en) | Preparation method of regenerated cellulose fiber extracted from lotus plants | |
| CN101368328B (en) | Preparation method for hydroxyethyl group chitosan fiber | |
| CN115044992A (en) | Preparation method of viscose macrobio-fiber containing seaweed active ingredients | |
| CN103451914A (en) | Production method of antibacterial silk fabric | |
| CN108468098A (en) | Antibacterial textile fabric, antibacterial textile fabric and antibacterial textile fabric preparation method | |
| CN116623339A (en) | Antibacterial chitosan nano silver fiber fabric | |
| CN107158030A (en) | A kind of new silver-containing antibacterial product and preparation method thereof | |
| CN109267180B (en) | Colored alginate fiber with stable coloring and preparation method thereof | |
| CN113005633A (en) | Antibacterial nanofiber membrane and preparation method and application thereof | |
| CN106436017B (en) | A kind of chitosan oligosaccharide cellulose fibre spunlace non-woven cloth and its production method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20210430 |
|
| WW01 | Invention patent application withdrawn after publication |