CN112690449A - Cereal conditioning porridge for middle-aged and old people - Google Patents

Cereal conditioning porridge for middle-aged and old people Download PDF

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Publication number
CN112690449A
CN112690449A CN202011393035.8A CN202011393035A CN112690449A CN 112690449 A CN112690449 A CN 112690449A CN 202011393035 A CN202011393035 A CN 202011393035A CN 112690449 A CN112690449 A CN 112690449A
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Prior art keywords
parts
folic acid
water
mixture
aged
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Inventor
岳玉荣
易斌
韩雅慧
龚旭
钟敏
张李丹
郭文霞
侯彦爽
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Jianchangbang Pharmacy Co ltd
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Jianchangbang Pharmacy Co ltd
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Priority to CN202011393035.8A priority Critical patent/CN112690449A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/03Products from fruits or vegetables; Preparation or treatment thereof consisting of whole pieces or fragments without mashing the original pieces
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/10Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23L25/00Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
    • A23L25/20Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof consisting of whole seeds or seed fragments
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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    • A23L33/15Vitamins
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    • A23L7/00Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10Cereal-derived products
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Abstract

The invention relates to the technical field of health-care and health-preserving foods, and particularly relates to a middle-aged and old cereal conditioning porridge, which comprises the following components in parts by weight: 10-15 parts of gordon euryale seed, 10-15 parts of fermented soybean, 10-15 parts of Chinese yam, 1-6 parts of coix seed, 1-6 parts of hawthorn, 3-9 parts of Chinese magnoliavine fruit, 1-5 parts of polygonatum, 1-5 parts of longan pulp, 2-5 parts of wolfberry fruit, 1-5 parts of raspberry, 1-5 parts of poria cocos, 1-5 parts of raw lily, 1-5 parts of lotus seed, 0.5-3 parts of folic acid compounds, 3-8 parts of raw licorice and 0.5-3 parts of fructus amomi.

Description

Cereal conditioning porridge for middle-aged and old people
Technical Field
The invention relates to the technical field of health-care and health-preserving foods, and in particular relates to a cereal conditioning porridge for middle-aged and old people.
Background
In addition to the inevitable deterioration of the body organ system with age, which is the inevitable consequence of the body of a person with age, with aging, there are changes in other body characteristics, and the body organs and characteristics change gradually with age. For example, the older the patient, the more dull the reaction. This is because, after a long time, the growth rate of human neurotransmitters is slowed down, which results in a slow response that gradually degrades the previously sensitive sensory perception, for example: the sense of hearing, taste and vision will all be degraded.
After the age is increased, the digestive ability is reduced, and due to the reduction of the number of digestive enzymes in the body, the old people cannot fully absorb vitamins and nutritional ingredients like young people, so that partial loss of nutrition can be caused, and scientific dietary habits have a certain protective effect on the digestive system.
The middle-aged and the elderly have bad intestines and stomach, which are important in relation to the growth of age and the change of body. With age, various organs of the body have degenerative normal phenomena, such as impaired digestion, slower intestinal motility, easy occurrence of constipation, and the like. The middle-aged and the elderly have the hypofunction of the intestines and the stomach due to organism reasons, so the health care of the intestines and the stomach is pertinently enhanced, and the health care tea has positive significance for disease prevention and life prolonging and peace of people in the late year.
At present, three methods are mainly used for strengthening the health care of the intestines and the stomach of the middle-aged and the elderly, the first method is a pure food which mainly supplements nutrition but lacks the treatment effect on human bodies; the second method is pure medicine, which mainly takes nourishing medicines such as ginseng and astragalus root, pilose antler, medlar and the like as main materials and is mostly products such as nourishing paste, wine, electuary and the like; the third method is a health food combining medicine and food, such as tuckahoe cake, coix seed porridge and the like, which is a single recipe and has weak pertinence and effectiveness to chronic diseases. Moreover, most health-care foods are added with traditional Chinese medicines, so that the medicine taste is rich and the mouthfeel is poor.
Chinese patent application CN104940606A discloses a deer-horn gelatin health care product for conditioning eight kinds of unbalanced constitutions, which comprises the following raw materials in parts by mass: 1-10 parts of deer glue powder, 1-10 parts of ginseng, 1-10 parts of cordyceps militaris, 0.1-4 parts of saussurea involucrata culture, 1-6 parts of rhizoma polygonati, 1-4 parts of polygonatum odoratum, deer blood, deer bone marrow powder, maca powder, moringa oleifera leaves, earthworm protein, noni pulp, wolfberry fruit, mulberry, emblic leafflower fruit, dunaliella salina, white hyacinth bean, longan pulp, cassia seed, lily, gorgon fruit, sea buckthorn, sharpleaf galangal fruit, Chinese date, elsholtzia, spina date seed, poria cocos, fingered citron, citrus red, peach kernel, tortoise, coix seed, honeysuckle, liquorice, ginkgo seed, Chinese yam, papaya, nutmeg, pine pollen, roxburgh rose, eucommia male flower, rose, gorgon fruit, lindera aggregate leaves, honey, krill oil, plukenetia wheat oligopeptide, yeast beta-glucan, milk mineral salt, tomato seed oil and eucommia seed oil. Has good curative effect on various deficiency syndromes of people with deficiency of both qi and blood, weak viscera function and sub-health people with low immunity.
Chinese patent application CN104605357A discloses a functional health product for conditioning sub-health. It is prepared from the following Chinese medicaments: astragalus root, Siberian solomonseal rhizome, Chinese yam, lotus seed, amomum fruit, lucid ganoderma, tuckahoe, hawthorn fruit, medlar, fleece-flower root, chrysanthemum, white paeony root, bupleurum root, nutgrass galingale rhizome, twotooth achyranthes root, medicinal indianmulberry root, glossy privet fruit, prepared rehmannia root, tortoise shell, American ginseng, tall gastrodia tuber, angelica, Szechuan lovage rhizome, safflower, danshen root, ginkgo leaf, sanchi, dwarf lilyturf tuber, Chinese magnoliavine fruit. The health care product can not only condition sub-health, but also be a good product for health preserving and health care, relieving fatigue, building up body and delaying senility, is a good prescription for long-term taking for health care of cardiovascular and cerebrovascular diseases, immune function conditioning and disease resistance, and can be taken for a long time without toxic and side effects. The health product is used for conditioning sub-health people, and more than 95% of people recover health.
However, the two inventions are added with a plurality of traditional Chinese medicines, so that the two inventions are rich in medicinal taste and easy to generate side effects.
Chinese patent application CN109770168A discloses a health preserving porridge formula comprising black rice 200g, glutinous millet 200g, glutinous sorghum 200g, polished round-grained rice 200g, fried buckwheat 200g, Chinese yam 50g, lotus seed 50g, coix seed 50g, gordon euryale seed 50g, mung bean 50g, black bean 50g, red bean 50g, peanut 50g, fried white hyacinth bean 50g, Chinese date 50g, wolfberry fruit 50g, kudzu vine root 50g and poria cocos 50 g. The brewing porridge is prepared according to a certain amount of medicinal and edible varieties, so that the brewing porridge has the health-preserving connotation, the food therapy effect is increased, the nourishing effects of regulating intestines and stomach, tonifying spleen and replenishing qi are realized, and the brewing porridge is convenient and quick to eat. The requirements of people in modern society on health preservation are met. However, the effect of the invention on coordinating intestines and stomach needs to be further improved, and the effect on preventing and treating senile dementia is not obvious.
Therefore, it is very necessary to develop a cereal conditioning porridge for middle and old aged people which can solve the above technical problems.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide the grain conditioning porridge for the middle-aged and the elderly, which has good taste and obvious effects of conditioning gastrointestinal functions, enhancing immunity and preventing and treating cardiovascular and cerebrovascular diseases.
The invention is realized by the following technical scheme:
the composition comprises the following components in parts by weight: 10-15 parts of gordon euryale seed, 10-15 parts of fermented soybean, 10-15 parts of Chinese yam, 1-6 parts of coix seed, 1-6 parts of hawthorn, 3-9 parts of Chinese magnoliavine fruit, 1-5 parts of fragrant solomonseal rhizome, 1-5 parts of dried longan pulp, 2-5 parts of medlar, 1-5 parts of raspberry, 1-5 parts of tuckahoe, 1-5 parts of raw lily, 1-5 parts of lotus seed, 0.5-3 parts of folic acid compound, 3-8 parts of raw licorice and 0.5-3 parts of amomum fruit.
Preferably, the composition comprises the following components in parts by weight: 12-14 parts of gordon euryale seed, 12-14 parts of fermented soybean, 12-14 parts of Chinese yam, 2-5 parts of coix seed, 2-5 parts of hawthorn, 4-8 parts of Chinese magnoliavine fruit, 2-4 parts of polygonatum, 2-4 parts of longan pulp, 2-4 parts of wolfberry fruit, 2-4 parts of raspberry, 2-4 parts of poria cocos, 2-4 parts of raw lily, 2-4 parts of lotus seed, 1-2 parts of folic acid compounds, 4-6 parts of raw licorice and 1-2 parts of fructus amomi.
Preferably, the folic acid compounds are one or more of folic acid, leucovorin, L-methyl folic acid, pharmaceutically acceptable salts of folic acid, active metabolites of folic acid or pharmaceutically acceptable salts of folic acid, and substances metabolized and/or generated in vivo.
The invention also relates to a cereal conditioning porridge for middle and old aged people, which comprises the composition.
The invention also relates to a preparation method of the cereal conditioning porridge for the middle-aged and the elderly, which comprises the following steps:
(1) cleaning fructus Schisandrae chinensis, rhizoma Polygonati Odorati, Poria, Glycyrrhrizae radix and fructus Amomi, decocting with water, and filtering to obtain extractive solution;
(2) washing semen euryales, fermented soybean, Chinese yam, semen coicis, hawthorn and lotus seeds, adding the extracting solution obtained in the step (1), adding water, and steaming to obtain a mixture A;
(3) cleaning arillus longan, fructus Lycii and Rubi fructus, adding water, and heating to boil to obtain mixture B;
(4) mixing mixture A and mixture B, adding water, decocting, adding Bulbus Lilii, cooling, adding folic acid compounds, and sterilizing.
Preferably, the cooking process in the step (1) is cooking for 20-30min by slow fire.
Preferably, the amount of water added in step (1) is 3-6 times of the total mass of the raw materials in step (1).
Preferably, the amount of water added in step (2) is 1.5-3 times of the total mass of the drug in step (2).
Preferably, steaming is performed for 20-30min in step (2).
Preferably, the amount of water added in step (3) is 1-2 times the total mass of the raw materials in step (3).
Preferably, the amount of water added in step (4) is 1 to 3 times the total mass of mixture A and mixture B.
Preferably, the water is added in the step (4) for stewing for 2-3h, and then the raw lily is added for stewing for 5-10 min.
More preferably, the preparation method comprises the following steps:
(1) cleaning fructus Schisandrae chinensis, rhizoma Polygonati Odorati, Poria, Glycyrrhrizae radix and fructus Amomi, adding 3-6 times of water, decocting with slow fire for 20-30min, and filtering to obtain extractive solution;
(2) washing semen euryales, fermented soybean, Chinese yam, semen coicis, hawthorn and lotus seeds, adding the extracting solution in the step (1), adding 1.5-3 times of water, and steaming for 20-30min to obtain a mixture A;
(3) cleaning arillus longan, fructus Lycii and Rubi fructus, adding 1-2 times of water, and heating to boil to obtain mixture B;
(4) mixing mixture A and mixture B, adding 1-3 times of water, stewing for 2-3h, adding raw Bulbus Lilii, decocting for 5-10 min, cooling, adding folic acid compounds, and sterilizing.
Preferably, the step (4) is performed by adding white sugar while adding water.
The invention also relates to the application of the composition in preparing health-care food for enhancing the gastrointestinal function and immunity of the middle-aged and the elderly and preventing and treating cardiovascular and cerebrovascular diseases.
The invention has the beneficial effects that:
(1) the beans compensate for the lack of lysine in grains, supplement nutrition, and fermented soybean can also improve cerebral blood flow and prevent and treat senile dementia.
(2) The invention harmonizes the drug properties of various foods and promotes the exertion of drug effects; for example, fructus amomi is added, so that the liver protection and digestion assistance effects of the fructus amomi are utilized, and other components are added to eliminate possible side effects of tonics, thereby improving the safety of food.
(3) The folic acid is added separately, so that the problems of extremely unstable folic acid and easy oxidation in natural food are solved, the absorption and utilization rate of human bodies to folic acid is improved, and the risk of damage to multiple systems of the bodies due to folic acid deficiency can be avoided. In addition, folic acid and other components have synergistic effect, and can enhance gastrointestinal function and immunity, and prevent and treat cardiovascular and cerebrovascular diseases.
(4) The middle-aged and old cereal conditioning porridge disclosed by the invention is rich in nutrition, good in color and appearance, soft, glutinous, fragrant and smooth, good in taste, high in acceptance of people, reasonable in component ratio, and capable of comprehensively and effectively preventing and relieving the sub-health problem of middle-aged and old people.
Detailed Description
The invention will be further described with reference to specific embodiments, and the advantages and features of the invention will become apparent as the description proceeds. These examples are illustrative only and do not limit the scope of the present invention in any way. It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention, and that such changes and modifications may be made without departing from the spirit and scope of the invention.
Example 1
The middle-aged and old cereal conditioning porridge comprises the following components in parts by weight: 10 parts of gordon euryale seed, 10 parts of fermented soybean, 10 parts of Chinese yam, 1 part of coix seed, 1 part of hawthorn, 3 parts of Chinese magnoliavine fruit, 1 part of fragrant solomonseal rhizome, 1 part of dried longan pulp, 2 parts of barbary wolfberry fruit, 1 part of raspberry, 1 part of tuckahoe, 1 part of raw lily, 1 part of lotus seed, 0.5 part of folic acid, 3 parts of raw licorice and 0.5 part of fructus amomi.
The preparation method of the cereal conditioning porridge for the middle-aged and the elderly comprises the following steps:
(1) cleaning fructus Schisandrae chinensis, rhizoma Polygonati Odorati, Poria, Glycyrrhrizae radix and fructus Amomi, adding 3 times of water, decocting with slow fire for 20min, and filtering to obtain extractive solution;
(2) washing semen euryales, fermented soybean, Chinese yam, semen coicis, hawthorn and lotus seeds, adding the extracting solution in the step (1), adding 1.5 times of water, and steaming for 20min to obtain a mixture A;
(3) cleaning arillus longan, fructus Lycii and Rubi fructus, adding 1 times of water, and heating to boil to obtain mixture B;
(4) mixing mixture A and mixture B, adding 1 times of water, stewing for 2 hr, adding Bulbus Lilii, decocting for 5min, cooling, adding folic acid compounds, and sterilizing.
Example 2
The middle-aged and old cereal conditioning porridge comprises the following components in parts by weight: 15 parts of gordon euryale seed, 15 parts of fermented soybean, 15 parts of Chinese yam, 6 parts of coix seed, 6 parts of hawthorn, 9 parts of Chinese magnoliavine fruit, 5 parts of fragrant solomonseal rhizome, 5 parts of dried longan pulp, 5 parts of barbary wolfberry fruit, 5 parts of raspberry, 5 parts of tuckahoe, 5 parts of raw lily, 5 parts of lotus seed, 3 parts of formyl tetrahydrofolic acid, 8 parts of raw licorice and 3 parts of fructus amomi.
The preparation method of the cereal conditioning porridge for the middle-aged and the elderly comprises the following steps:
(1) cleaning fructus Schisandrae chinensis, rhizoma Polygonati Odorati, Poria, Glycyrrhrizae radix and fructus Amomi, adding 6 times of water, decocting with slow fire for 30min, and filtering to obtain extractive solution;
(2) washing semen euryales, fermented soybean, Chinese yam, semen coicis, hawthorn and lotus seeds, adding the extracting solution in the step (1), adding 3 times of water, and steaming for 30min to obtain a mixture A;
(3) cleaning arillus longan, fructus Lycii and Rubi fructus, adding 2 times of water, and heating to boil to obtain mixture B;
(4) mixing mixture A and mixture B, adding 3 times of water, decocting for 3 hr, adding Bulbus Lilii, decocting for 10 min, cooling, adding folic acid compounds, and sterilizing.
Example 3
The middle-aged and old cereal conditioning porridge comprises the following components in parts by weight: 12 parts of gordon euryale seed, 12 parts of fermented soybean, 12 parts of Chinese yam, 3 parts of coix seed, 4 parts of hawthorn, 6 parts of Chinese magnoliavine fruit, 3 parts of fragrant solomonseal rhizome, 3 parts of dried longan pulp, 4 parts of barbary wolfberry fruit, 3 parts of raspberry, 3 parts of tuckahoe, 3 parts of raw lily, 3 parts of lotus seed, 1 part of L-methyl folic acid, 5 parts of raw licorice and 2 parts of fructus amomi.
The preparation method of the cereal conditioning porridge for the middle-aged and the elderly comprises the following steps:
(1) cleaning fructus Schisandrae chinensis, rhizoma Polygonati Odorati, Poria, Glycyrrhrizae radix and fructus Amomi, adding 5 times of water, decocting with slow fire for 25min, and filtering to obtain extractive solution;
(2) washing semen euryales, fermented soybean, Chinese yam, semen coicis, hawthorn and lotus seeds, adding the extracting solution in the step (1), adding 2 times of water, and steaming for 25min to obtain a mixture A;
(3) cleaning arillus longan, fructus Lycii and Rubi fructus, adding 1.5 times of water, and heating to boil to obtain mixture B;
(4) mixing mixture A and mixture B, adding 2 times of water, decocting for 2.5 hr, adding Bulbus Lilii, decocting for 7 min, cooling, adding folic acid compounds, and sterilizing.
Comparative example 1
The difference from the embodiment 3 is that the total dosage of the gorgon fruit, the fermented soybean and the Chinese yam is not changed, the dosage proportion of the three components is different, 12 parts of the gorgon fruit, 12 parts of the fermented soybean and 12 parts of the Chinese yam are replaced by 5 parts of the gorgon fruit, 10 parts of the fermented soybean and 21 parts of the Chinese yam, and the other conditions are the same.
Comparative example 2
The difference from the embodiment 3 is that the total dosage of the gorgon fruit, the fermented soybean and the Chinese yam is not changed, the dosage proportion of the three components is different, 12 parts of the gorgon fruit, 12 parts of the fermented soybean and 12 parts of the Chinese yam are replaced by 21 parts of the gorgon fruit, 10 parts of the fermented soybean and 5 parts of the Chinese yam, and the other conditions are the same.
Comparative example 3
The difference from the embodiment 3 is only that the gorgon fruit is replaced by the lotus seed with similar effect, and the rest conditions are the same, specifically as follows:
the middle-aged and old cereal conditioning porridge comprises the following components in parts by weight: 12 parts of fermented soybean, 12 parts of Chinese yam, 3 parts of coix seed, 4 parts of hawthorn, 6 parts of Chinese magnoliavine fruit, 3 parts of fragrant solomonseal rhizome, 3 parts of dried longan pulp, 4 parts of barbary wolfberry fruit, 3 parts of raspberry, 3 parts of poria cocos, 3 parts of raw lily, 15 parts of lotus seed, 1 part of L-methyl folic acid, 5 parts of raw licorice and 2 parts of fructus amomi.
Comparative example 4
The only difference from example 3 is that L-methyl folic acid was replaced with an equal amount of vitamin C, and the other conditions were the same.
Comparative example 5
The difference from the example 3 is only that the extraction sequence of each component is different, and the rest conditions are the same, and the specific steps are as follows:
the preparation method of the cereal conditioning porridge for the middle-aged and the elderly comprises the following steps:
(1) cleaning fructus Schisandrae chinensis, Coicis semen, Poria, Glycyrrhrizae radix and fructus Amomi, adding 5 times of water, decocting with slow fire for 25min, and filtering to obtain extractive solution;
(2) washing semen euryales, fermented soybean, Chinese yam, polygonatum odoratum, hawthorn and lotus seeds, adding the extracting solution obtained in the step (1), adding 2 times of water, and steaming for 25min to obtain a mixture A;
(3) cleaning arillus longan, fructus Lycii and Rubi fructus, adding 1.5 times of water, and heating to boil to obtain mixture B;
(4) mixing mixture A and mixture B, adding 2 times of water, decocting for 2.5 hr, adding Bulbus Lilii, decocting for 7 min, cooling, adding folic acid compounds, and sterilizing.
Comparative example 6
The difference from the embodiment 3 is that the filtering is not carried out after the Chinese character is cooked by fire in the step (1), the Chinese character is directly added into the step (2), the raw material slag in the step (1) is removed after the steaming in the step (2) is finished, and the other conditions are the same.
Test example 1
Test for enhancing gastrointestinal function
135 patients with long-term constipation were randomly selected, aged 45-65 years, and randomly divided into 9 groups of 15 persons each, and each group was eaten with the middle-aged and old cereal conditioning porridge of examples 1-3 and comparative examples 1-6, respectively, 100g per day, and the subjects were asked to perform effect evaluation 7 days later without changing the original eating habits and normal diet during the experiment. The method has the following advantages: the constipation symptom is relieved or disappeared; and (4) invalidation: the constipation symptoms do not change or worsen. The evaluation results are shown in table 1.
TABLE 1
Figure BDA0002811544450000061
Figure BDA0002811544450000071
Test example 2
Enhanced immune function test
1. And (3) testing a sample: the middle and old aged cereal-conditioned porridge of examples 1 to 3 and comparative examples 1 to 6.
2. Experimental animals and environment: SPF-grade KM female mice weighing 18-22 g; laboratory temperature of the laboratory: 22-25 ℃, relative humidity: 55 to 70 percent.
3. The experimental method comprises the following steps: the mice were randomly divided into 10 groups of 5 mice each, namely a negative control group (directly given distilled water at 7.5mL/kg. bw), an experimental group (total of 3 groups, the middle and old aged cereal conditioning porridge of examples 1 to 3 was gavaged at 7.5mL/kg. bw), and a control group (total of 6 groups, the middle and old aged cereal conditioning porridge of comparative examples 1 to 6 was gavaged at 7.5mL/kg. bw), and were gavaged for 30 days.
3.1 ConA-induced splenic lymphocyte transformation experiments in mice
After each group of test mice are continuously infused with stomach for 30 days according to the specified dosage, the mice are killed by cervical dislocation, and the spleen is taken out aseptically to prepare single cell suspension (the cell concentration is 1 multiplied by 10)7one/mL). The mouse splenocyte suspension was added to a 24-well plate, two duplicate wells were used for each treatment, 1mL of ConA was added to one well, 50. mu.L of double distilled water was added to the other well as a control, and the plate was placed in 5% CO2And cultured in a carbon dioxide incubator at 37 ℃ for 48 hours. 4h before the culture is finished, adding 50 mu L/hole MTT (5mg/mL), continuing to culture, adding 1mL DMSO into each hole after the culture is finished, blowing and uniformly mixing to completely dissolve purple crystals, and subpackagingThe cells were plated in 96-well plates, 3 multiple wells were dispensed per well, and OD was measured at a wavelength of 570nm using a microplate reader. The optical density of the ConA-added wells minus the optical density of the non-ConA-added wells represents the proliferative capacity of lymphocytes. Lymphocyte proliferation capacity-ConA well OD value-control well OD value. The results are shown in Table 2.
TABLE 2
Figure BDA0002811544450000072
Figure BDA0002811544450000081
3.2 Dinitrofluorobenzene (DNFB) induced delayed allergy (DTH) assay
After each group of test mice are continuously subjected to intragastric administration for 30 days according to the specified dosage, the abdomen of the mice is unhaired, 50 mu L of 1% DNFB acetone sesame oil solution is smeared for sensitization, 5 days after sensitization, 10 mu L of 1% DNFB acetone sesame oil solution is evenly smeared on the right ear of the mice for attacking, the left ear is smeared with the same amount of acetone sesame oil solution for contrast, the mice are killed 24 hours after the attacking, the left and right ear shells are cut off, the ear pieces with the diameter of 8mm are taken at the same part for weighing, and the weight difference of the left and right ear pieces is taken as the swelling degree. The results are shown in Table 3.
TABLE 3
Group of Swelling degree (mg)
Negative control group 2.81±1.07
Example 1 5.17±3.15
Example 2 5.19±3.72
Example 3 5.22±3.49
Comparative example 1 4.63±2.05
Comparative example 2 4.47±2.47
Comparative example 3 4.65±1.91
Comparative example 4 4.60±2.05
Comparative example 5 4.51±2.26
Comparative example 6 4.56±3.74
The above detailed description is specific to one possible embodiment of the present invention, and the embodiment is not intended to limit the scope of the present invention, and all equivalent implementations or modifications without departing from the scope of the present invention should be included in the technical scope of the present invention.

Claims (10)

1. The composition is characterized by comprising the following components in parts by weight: 10-15 parts of gordon euryale seed, 10-15 parts of fermented soybean, 10-15 parts of Chinese yam, 1-6 parts of coix seed, 1-6 parts of hawthorn, 3-9 parts of Chinese magnoliavine fruit, 1-5 parts of fragrant solomonseal rhizome, 1-5 parts of dried longan pulp, 2-5 parts of medlar, 1-5 parts of raspberry, 1-5 parts of tuckahoe, 1-5 parts of raw lily, 1-5 parts of lotus seed, 0.5-3 parts of folic acid compound, 3-8 parts of raw licorice and 0.5-3 parts of amomum fruit.
2. The composition according to claim 1, which comprises the following components in parts by weight: 12-14 parts of gordon euryale seed, 12-14 parts of fermented soybean, 12-14 parts of Chinese yam, 2-5 parts of coix seed, 2-5 parts of hawthorn, 4-8 parts of Chinese magnoliavine fruit, 2-4 parts of polygonatum, 2-4 parts of longan pulp, 2-4 parts of wolfberry fruit, 2-4 parts of raspberry, 2-4 parts of poria cocos, 2-4 parts of raw lily, 2-4 parts of lotus seed, 1-2 parts of folic acid compounds, 4-6 parts of raw licorice and 1-2 parts of fructus amomi.
3. The composition of claim 1, wherein the folic acid compounds are one or more of folic acid, leucovorin, L-methyl folic acid, pharmaceutically acceptable salts of folic acid, active metabolites of folic acid or pharmaceutically acceptable salts of folic acid, and substances metabolized and/or generated in vivo.
4. A cereal conditioning porridge for middle and old aged people, comprising the composition of any one of claims 1 to 3.
5. A method for preparing the middle-aged and old cereal conditioning porridge as claimed in claim 4, which is characterized by comprising the following steps:
(1) cleaning fructus Schisandrae chinensis, rhizoma Polygonati Odorati, Poria, Glycyrrhrizae radix and fructus Amomi, decocting with water, and filtering to obtain extractive solution;
(2) washing semen euryales, fermented soybean, Chinese yam, semen coicis, hawthorn and lotus seeds, adding the extracting solution obtained in the step (1), adding water, and steaming to obtain a mixture A;
(3) cleaning arillus longan, fructus Lycii and Rubi fructus, adding water, and heating to boil to obtain mixture B;
(4) mixing mixture A and mixture B, adding water, decocting, adding Bulbus Lilii, cooling, adding folic acid compounds, and sterilizing.
6. The preparation method according to claim 5, wherein the cooking process in the step (1) is carried out for 20-30 min; the amount of the added water is 3 to 6 times of the total mass of the raw materials in the step (1).
7. The method according to claim 5, wherein the amount of water added in step (2) is 1.5 to 3 times the total mass of the drug in step (2); steaming for 20-30min in step (2).
8. The process according to claim 5, wherein the amount of water added in step (3) is 1 to 2 times the total mass of the raw materials in step (3).
9. The production method according to claim 5, wherein water is added in the step (4) in an amount of 1 to 3 times the total mass of the mixture A and the mixture B; adding water, stewing for 2-3h, adding raw Bulbus Lilii, and decocting for 5-10 min.
10. Use of the composition of any one of claims 1 to 3 for preparing a health food for enhancing gastrointestinal function and immunity of middle-aged and elderly people, and preventing and treating cardiovascular and cerebrovascular diseases.
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CN109105727A (en) * 2017-06-26 2019-01-01 张靖宏 A kind of invigorating the spleen to clear away damp pathogen reinforces the kidney congee secret recipe

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