CN112587463A

CN112587463A - Long-acting skin care composition for removing freckles and concealing blemishes and preparation method thereof

Info

Publication number: CN112587463A
Application number: CN202010726814.9A
Authority: CN
Inventors: 钱凤英
Original assignee: Guangzhou Yuanmeisheng Cosmetics Co ltd
Current assignee: Guangzhou Yuanmeisheng Cosmetics Co ltd
Priority date: 2020-07-26
Filing date: 2020-07-26
Publication date: 2021-04-02

Abstract

The invention relates to a skin care composition, in particular to a long-acting skin care composition for removing freckles and concealing blemishes and a preparation method thereof, wherein the skin care composition comprises the following raw materials: calendula officinalis extract, bletilla striata extract, Chinese waxgourd stem extract, dandelion water extract, mulberry root extract, glabridin, borage extract, Chinese sprangletop extract, beta-methyl carboxylic acid polydextrose, nicotinamide, allantoin, rose essential oil, wormwood essential oil, traditional Chinese medicine extract and deionized water. The calendula extract, the bletilla striata extract, the Chinese waxgourd stem extract, the dandelion water extract, the mulberry root extract, the glabridin, the borage extract and the Chinese iris extract are compounded for use, and the beta-methyl carboxylic acid polydextrose, the nicotinamide and the allantoin are added, so that the free radicals can be effectively inhibited, the skin melanin deposition can be prevented and improved, the plaque can be relieved and lightened, and the skin can be recovered to be in a bright white and clean state; most raw materials are natural, no hormone is added, and the use is safe and relieved.

Description

Long-acting skin care composition for removing freckles and concealing blemishes and preparation method thereof

Technical Field

The invention relates to a skin care composition, in particular to a long-acting skin care composition for removing freckles and concealing blemishes and a preparation method thereof.

Background

Melanin (melanin) is an important factor determining human skin color, and it is biosynthesized in melanosomes in melanocytes of the basal layer of the epidermis. Under normal physiological conditions, melanin in the skin protects the skin from ultraviolet light. When the melanin anabolism mechanism is disturbed due to external invasion, hormone imbalance, aging or other factors, the melanin in the basal layer of the epidermis is increased, the color of partial or whole skin is deepened, and pigmentation skin diseases such as freckle, chloasma, cyasma, senile plaque, melanoma and the like are caused, so that the appearance of a human is influenced. The biosynthesis steps of the melanin comprise: tyrosine in melanocyte tissue is converted into dopa under the action of tyrosinase, dopa is further converted into dopaquinone under the catalysis of tyrosinase, dopaquinone is further converted into dopachrome, 5, 6-dihydroxyindole, 5, 6-indoloquinone, and finally into melanin. Melanin granules are synthesized and transported by the dendrites into keratinocytes.

In the prior art, the freckle removing product is mainly used for chloasma, and most experts think that the chloasma can be related to the following factors: ultraviolet radiation, endocrine dyscrasia, heredity, oxygen free radicals, drugs and cosmetics, oral drugs, local micro-ecology, systemic pathological changes of organisms, emotional fluctuation and the like, and the specific pathogenesis of the diseases is not clear; whitening is required for removing freckles, and skin whitening agents usually take tyrosinase as an action target, and reduce the generation of skin melanin by inhibiting the activity of the tyrosinase or blocking the reaction of the tyrosinase to generate the melanin, so that the skin whitening effect is achieved. Most of the skin whitening agents adopt hydrogen peroxide, mercuric amino chloride and various phenolic derivatives as skin whitening agents, the compounds can rapidly break up melanin tissues to achieve the effect of rapid whitening, but have adverse effects of corrosivity, cytotoxicity, anaphylaxis and the like on skin, are poor in safety, not ideal in effect and large in skin irritation, and have the need of continuously researching freckle-removing cosmetics.

Disclosure of Invention

The invention aims to provide a long-acting skin care composition for removing freckles and concealing blemishes and a preparation method thereof.

In order to achieve the above object, the present invention adopts the following technical solutions

A long-acting skin care composition for removing freckles and concealing blemishes comprises the following raw materials: calendula officinalis extract, bletilla striata extract, Chinese waxgourd stem extract, dandelion water extract, mulberry root extract, glabridin, borage extract, Chinese sprangletop extract, beta-methyl carboxylic acid polydextrose, nicotinamide, allantoin, rose essential oil, wormwood essential oil, traditional Chinese medicine extract and deionized water.

Preferably, the long-acting skin care composition for removing the freckles and concealing the blemishes comprises the following raw materials in parts by weight: 2-10 parts of calendula extract, 2-10 parts of bletilla striata extract, 2-10 parts of Chinese waxgourd stem extract, 1-5 parts of dandelion water extract, 1-5 parts of mulberry root extract, 1-3 parts of glabridin, 1-5 parts of borage extract, 2-8 parts of Chinese sprangle extract, 0.6-1.5 parts of beta-methyl carboxylic acid polydextrose, 0.3-1.0 part of nicotinamide, 0.6-1.2 parts of allantoin, 0.6-1.4 parts of rose essential oil, 0.3-0.8 part of wormwood essential oil, 2-4 parts of traditional Chinese medicine extract and 30-50 parts of deionized water.

Preferably, the long-acting skin care composition for removing the freckles and concealing the blemishes comprises the following raw materials in parts by weight: 6 parts of calendula extract, 6 parts of bletilla striata extract, 6 parts of Chinese waxgourd stem extract, 3 parts of dandelion water extract, 3 parts of mulberry root extract, 2 parts of glabridin, 3 parts of borage extract, 5 parts of Chinese sprangletop extract, 1.0 part of beta-methyl carboxylic acid polydextrose, 0.7 part of nicotinamide, 0.9 part of allantoin, 1.0 part of rose essential oil, 0.6 part of wormwood essential oil, 3 parts of traditional Chinese medicine extract and 40 parts of deionized water.

Preferably, the calendula extract, bletilla striata extract, Chinese waxgourd stem extract, dandelion aqueous extract, mulberry root extract, glabridin, borage extract, Chinese iris extract and Chinese medicinal extract are subjected to ultramicro molecular grinding, and the particle size is not more than 40 nm.

Preferably, the weight ratio of the traditional Chinese medicine extract is (1-2): 1 a mixture of an extract of ledebouriella seseloides and an extract of angelica.

Preferably, the solvent of the Chinese medicinal extract is CO₂The supercritical fluid extract of (1).

A preparation method of a long-acting skin care composition for removing freckles and concealing blemishes comprises the following steps:

s1, putting deionized water into a stirring pot at room temperature, starting the stirring pot, rotating at the speed of 50-100r/min, sequentially and slowly adding the calendula extract, the bletilla striata extract, the Chinese waxgourd stem extract, the dandelion extract, the mulberry root extract, the glabridin, the borage extract, the malacopa extract and the traditional Chinese medicine extract, and stirring until the mixture is completely mixed and dissolved;

s2, heating to 50-65 ℃, sequentially adding glabridin and beta-methyl carboxylic acid polydextrose, continuing stirring at the rotating speed of 80-160r/min, uniformly stirring, and keeping the temperature for 20 min;

s3, after heat preservation is finished, cooling while stirring, adding nicotinamide and allantoin when the temperature is reduced to 40-45 ℃, keeping the temperature and continuously stirring until the nicotinamide and the allantoin are completely mixed and dissolved, and achieving a homogeneous state;

s4, after uniformly stirring, adjusting the rotation speed to 30-50r/min, naturally cooling to room temperature, adding rose essential oil and wormwood essential oil, and continuously stirring until the rose essential oil and the wormwood essential oil are completely mixed and dissolved to reach a homogeneous state;

and S5, checking, filtering and discharging after the inspection is qualified, and sealing for later use.

Preferably, in S2, the solution in the heat preservation state is treated by magnetic field strengthening technology for 20min, and the magnetic field intensity is 80-150 mT.

Preferably, in S2 and S3, the heating is assisted by heat radiation, and the wavelength of the electromagnetic wave is 200-.

Preferably, in S4, beta-ray irradiation is used for 3-5min during stirring.

The invention has the beneficial effects that:

1. according to the invention, the calendula extract, the bletilla striata extract, the Chinese waxgourd stem extract, the dandelion aqueous extract, the mulberry root extract, the glabridin, the borage extract and the Chinese iris extract are compounded for use, and the beta-methyl carboxylic acid polydextrose, the nicotinamide and the allantoin are added, so that the free radicals can be effectively inhibited, the skin melanin deposition can be prevented and improved, the plaque can be relieved and lightened, and the skin can be recovered to be in a bright, white and clean state.

2. The traditional Chinese medicine whitening component is added, so that the discharge of melanin can be accelerated from the inner part of the skin and the cell layer, and after the melanin is smoothly discharged, plaques are naturally lightened.

3. Most raw materials come from nature, no hormone is added, the use is safe and safe, and secondary damage to skin can not be caused.

4. Can be used for treating pigmentation dermatoses such as freckle, chloasma, cyasma, senile plaque, and melanoma.

Detailed Description

The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1:

a long-acting skin care composition for removing freckles and concealing blemishes comprises the following raw materials in parts by weight: 2 parts of calendula extract, 10 parts of bletilla striata extract, 2 parts of Chinese waxgourd stem extract, 5 parts of dandelion aqueous extract, 1 part of mulberry root extract, 3 parts of glabridin, 1 part of borage extract, 8 parts of Chinese sprangletop extract, 0.6 part of beta-methyl carboxylic acid polydextrose, 1.0 part of nicotinamide, 0.6 part of allantoin, 1.4 parts of rose essential oil, 0.3 part of wormwood essential oil, 4 parts of traditional Chinese medicine extract and 30 parts of deionized water.

Wherein, the weight ratio of the traditional Chinese medicine extract is 1: 1 a mixture of an extract of ledebouriella seseloides and an extract of angelica.

Example 2:

a long-acting skin care composition for removing freckles and concealing blemishes comprises the following raw materials in parts by weight: 6 parts of calendula extract, 6 parts of bletilla striata extract, 6 parts of Chinese waxgourd stem extract, 3 parts of dandelion water extract, 3 parts of mulberry root extract, 2 parts of glabridin, 3 parts of borage extract, 5 parts of Chinese sprangletop extract, 1.0 part of beta-methyl carboxylic acid polydextrose, 0.7 part of nicotinamide, 0.9 part of allantoin, 1.0 part of rose essential oil, 0.6 part of wormwood essential oil, 3 parts of traditional Chinese medicine extract and 40 parts of deionized water.

Wherein, the weight ratio of the traditional Chinese medicine extract is 2: 1 a mixture of an extract of ledebouriella seseloides and an extract of angelica.

Example 3:

a long-acting skin care composition for removing freckles and concealing blemishes comprises the following raw materials in parts by weight: 10 parts of calendula extract, 2 parts of bletilla striata extract, 10 parts of Chinese waxgourd stem extract, 1 part of dandelion aqueous extract, 5 parts of mulberry root extract, 1 part of glabridin, 5 parts of borage extract, 2 parts of Chinese sprangletop extract, 1.5 parts of beta-methyl carboxylic acid polydextrose, 0.3 part of nicotinamide, 1.2 parts of allantoin, 0.6 part of rose essential oil, 0.8 part of wormwood essential oil, 4 parts of traditional Chinese medicine extract and 50 parts of deionized water.

The preparation method of the long-acting skin care composition for removing freckles and concealing blemishes in the embodiment 1-3 comprises the following steps:

s1, putting deionized water into a stirring pot at room temperature, starting the stirring pot, rotating at the speed of 80r/min, sequentially and slowly adding the calendula extract, the bletilla striata extract, the Chinese waxgourd stem extract, the dandelion water extract, the mulberry root extract, the glabridin, the borage extract, the Chinese globeflower herb extract and the traditional Chinese medicine extract, and stirring until the mixture is completely mixed and dissolved;

s2, heating to 55 ℃, sequentially adding glabridin and beta-methyl carboxylic acid polydextrose, continuing stirring at a rotation speed of 120r/min, uniformly stirring, and keeping the temperature for 20 min;

s3, after heat preservation is finished, cooling while stirring, adding nicotinamide and allantoin when the temperature is reduced to 40 ℃, keeping stirring continuously until the mixture is completely dissolved and mixed, and achieving a homogeneous state;

s4, after uniformly stirring, adjusting the rotating speed to 40r/min, naturally cooling to room temperature, adding rose essential oil and wormwood essential oil, and continuously stirring until the rose essential oil and the wormwood essential oil are completely mixed and dissolved to reach a homogeneous state;

In order to improve the preparation effect, in S2, the solution in the heat preservation state is treated by adopting a magnetic field strengthening technology, the time is 20min, and the magnetic field intensity is 80-150 mT; under the action of the magnetic field, the molecular motion speed is accelerated, and the small liquid drops are promoted to generate internal circulation, so that various substances are more thoroughly homogenized, and the molecular dispersion degree is higher.

In S2 and S3, heat radiation is used for auxiliary heating, the wavelength of electromagnetic waves is 200-.

In S4, beta-ray irradiation is used for 3-5min during stirring to promote modification and crosslinking reaction of acid ester alcohol, thereby improving the use effect.

Experimental example 1

Allergy test

Experimental mode: selecting 30 volunteers, dividing the gauze into three groups, dividing the gauze into a plurality of small blocks of about 1 square centimeter, soaking the small blocks in distilled water, coating the long-acting skin care composition for removing freckles and covering blemishes prepared in the example 1-3 on one surface of the gauze, then respectively applying the long-acting skin care composition on five normal skins on the forearms and the backs of the volunteers, covering the five normal skins with 1.5 square centimeter airtight plastic films, and fixing the five normal skins with adhesive tapes. After one day, the gauze is removed and cleaned, observation is carried out, if abnormality such as erythema, pruritus, burning pain or redness and swelling occurs at a test position, the long-acting skin care combination for removing the freckles and covering the blemishes is proved to have irritation, and if the abnormality does not occur, the long-acting skin care combination for removing the freckles and covering the blemishes is proved to have no irritation. The results of the experiment are shown in table 1:

	volunteers 1 group	2 groups of volunteers	Volunteers 3 groups
				Example 1	Abnormal condition of test part	Abnormal condition of test part	Abnormal condition of test part
Example 2	Abnormal condition of test part	Abnormal condition of test part	Abnormal condition of test part
				Example 3	Abnormal condition of test part	Abnormal condition of test part	Abnormal condition of test part

TABLE 1

The experimental results in table 1 show that the long-acting skin care combination for removing freckles and covering prepared by the invention has no irritation to 1-3 groups of volunteers, which indicates that the long-acting skin care combination for removing freckles and covering prepared by the invention is safe to use.

Experimental example two

Clinical use case

Case 1, a person who is higher than the skin is a male, the person is 46 years old, and the face is determined to be chloasma in 2018, the long-acting skin care composition for removing the freckles and covering the blemishes prepared in example 2 is used from 3 months in 2019, the composition is applied after face washing every day, the composition is used once in the morning and evening, the blemishes are rechecked after 1 month, the freckles on the face become pale, after 3 months, part of the plaques almost disappear, the areas of other plaques are obviously reduced, after 6 months, the plaques basically disappear, the person is continuously used for 3 months, and the freckles.

Case 2, a certain woman, 38 years old, the left face appears spots from 2015, the number and the area of the left face are increased along with the increase of time, part of the left face gradually expands into pieces, and the multi-part treatment does not obviously improve, the long-acting skin care composition for removing the spots and covering the spots prepared in the example 2 is used from 2019 and 5 months, the long-acting skin care composition is applied after face washing every day, the skin care composition is used once in the morning and at night, the investigation is repeated after 1 month, the spots on the face become light, some small spots disappear after 3 months, the skin color of the face is recovered, the skin color continuously improves after 6 months, the number and the area of the spots are greatly reduced, the spots are almost disappeared in 9 months, the skin color of the spot position is not greatly different from that of other positions, and the.

Clinical cases show that the long-acting skin care composition for removing the freckles and concealing the blemishes, prepared by the invention, has good relieving and treating effects on symptoms such as facial stains, chloasma and the like.

Experimental example III

Some performance index tests were performed on the long-acting skin care combinations of the spot removing concealers of examples 1 to 3, and the test results were as follows:

1, appearance: white flowable fine paste.

2, fragrance type: the plant has faint scent.

3 viscosity 6000-.

4 Cold stability test (48 ℃ X24 h): and (4) passing.

5 Cold resistance stability test (-15 ℃ X24 h): and (4) passing.

In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

Finally, it should be noted that the above-mentioned preferred embodiments of the present invention are provided merely to help illustrate the present invention. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims

1. The long-acting skin care composition for removing freckles and concealing blemishes is characterized by comprising the following raw materials: calendula officinalis extract, bletilla striata extract, Chinese waxgourd stem extract, dandelion water extract, mulberry root extract, glabridin, borage extract, Chinese sprangletop extract, beta-methyl carboxylic acid polydextrose, nicotinamide, allantoin, rose essential oil, wormwood essential oil, traditional Chinese medicine extract and deionized water.

2. The long-acting skin care composition for removing freckles and concealing blemishes, according to claim 1, is characterized by comprising the following raw materials in parts by weight: 2-10 parts of calendula extract, 2-10 parts of bletilla striata extract, 2-10 parts of Chinese waxgourd stem extract, 1-5 parts of dandelion water extract, 1-5 parts of mulberry root extract, 1-3 parts of glabridin, 1-5 parts of borage extract, 2-8 parts of Chinese sprangle extract, 0.6-1.5 parts of beta-methyl carboxylic acid polydextrose, 0.3-1.0 part of nicotinamide, 0.6-1.2 parts of allantoin, 0.6-1.4 parts of rose essential oil, 0.3-0.8 part of wormwood essential oil, 2-4 parts of traditional Chinese medicine extract and 30-50 parts of deionized water.

3. The long-acting skin care composition for removing freckles and concealing blemishes, according to claim 2, is characterized by comprising the following raw materials in parts by weight: 6 parts of calendula extract, 6 parts of bletilla striata extract, 6 parts of Chinese waxgourd stem extract, 3 parts of dandelion water extract, 3 parts of mulberry root extract, 2 parts of glabridin, 3 parts of borage extract, 5 parts of Chinese sprangletop extract, 1.0 part of beta-methyl carboxylic acid polydextrose, 0.7 part of nicotinamide, 0.9 part of allantoin, 1.0 part of rose essential oil, 0.6 part of wormwood essential oil, 3 parts of traditional Chinese medicine extract and 40 parts of deionized water.

4. The long-acting skin care composition for removing freckles and concealing blemishes as claimed in claim 1, wherein calendula extract, bletilla striata extract, wax gourd vine extract, dandelion aqueous extract, mulberry root extract, glabridin, borage extract, Chinese globeflower extract and chinese herbal medicine extract are all subjected to ultra-micro molecular grinding, and the particle size is not more than 40 nm.

5. The long-acting skin care composition for removing freckles and concealing blemishes according to claim 1, wherein the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight (1-2): 1 a mixture of an extract of ledebouriella seseloides and an extract of angelica.

6. The long-acting skin care composition for removing freckles and concealing blemishes according to claim 1, wherein the solvent of the herbal extract is CO₂The supercritical fluid extract of (1).

7. A method of preparing a spot removing concealer combination for long-lasting skin care according to any of claims 1 to 6, comprising the steps of:

8. The method for preparing the long-acting skin care composition for removing freckles and concealers according to claim 7, wherein in S2, the solution in the heat preservation state is treated by a magnetic field strengthening technology for 20min, and the magnetic field intensity is 80-150 mT.

9. The method as claimed in claim 7, wherein the heat radiation is used for heating assistance in S2 and S3, and the wavelength of electromagnetic wave is 200-.

10. The method for preparing the long-acting skin care composition for removing freckles and concealers as claimed in claim 7, wherein in S4, beta-ray irradiation is used for 3-5min during stirring.