CN112481213B - 一种小分子活性肽在诱导hUC-MSCs分化方面的应用 - Google Patents
一种小分子活性肽在诱导hUC-MSCs分化方面的应用 Download PDFInfo
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1392—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from mesenchymal stem cells from other natural sources
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Abstract
Description
细胞表型分子阳性率 | 阳性率(%) |
CD73 | 98.5 |
CD90 | 98.8 |
CD105 | 98.2 |
CD34 | 2.73 |
CD45 | 1.69 |
HLA-DR | 0.87 |
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CN202011369787.0A CN112481213B (zh) | 2020-11-30 | 2020-11-30 | 一种小分子活性肽在诱导hUC-MSCs分化方面的应用 |
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CN202011369787.0A CN112481213B (zh) | 2020-11-30 | 2020-11-30 | 一种小分子活性肽在诱导hUC-MSCs分化方面的应用 |
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CN112481213B true CN112481213B (zh) | 2022-08-09 |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1549856A (zh) * | 2001-04-19 | 2004-11-24 | 金炫寿 | 使间充质干细胞分化为神经细胞的方法 |
CN105624115A (zh) * | 2015-12-03 | 2016-06-01 | 王意忠 | 一种诱导人脐带间充质干细胞分化为神经样细胞的培养基及其诱导方法 |
CN107058225A (zh) * | 2017-02-10 | 2017-08-18 | 郑州大学 | 一种复合诱导培养基以及采用该培养基诱导脐带间充质干细胞成神经元样细胞的方法 |
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2020
- 2020-11-30 CN CN202011369787.0A patent/CN112481213B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1549856A (zh) * | 2001-04-19 | 2004-11-24 | 金炫寿 | 使间充质干细胞分化为神经细胞的方法 |
CN105624115A (zh) * | 2015-12-03 | 2016-06-01 | 王意忠 | 一种诱导人脐带间充质干细胞分化为神经样细胞的培养基及其诱导方法 |
CN107058225A (zh) * | 2017-02-10 | 2017-08-18 | 郑州大学 | 一种复合诱导培养基以及采用该培养基诱导脐带间充质干细胞成神经元样细胞的方法 |
Non-Patent Citations (5)
Title |
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Exploring the enkephalinergic differentiation potential in adult stem cells for celltherapy and drug screening implications;Maryam Hafizi et al.;《In Vitro Cellular & Developmental Biology—Animal》;20121031;第48卷;第562-569页 * |
人脐带间充质干细胞向神经元样细胞诱导分化:两种方法的比较;王 武等;《中国组织工程研究》;20191231;第23卷(第1期);第41-46页 * |
枸杞多糖诱导人脐血间充质干细胞向神经元样细胞分化的实验研究;陈晓岚等;《现代生物医学进展》;20071231;第7卷(第8期);第1173-1175页 * |
诱导脐血间充质干细胞向神经元样细胞分化;陈 镭等;《中国组织工程研究》;20120603;第16 卷(第23 期);第4335-4338页 * |
黄芩苷体外诱导人脐带间充质干细胞分化为神经样细胞;赵家慧等;《河北医科大学学报》;20180831;第39卷(第8期);第903-907页 * |
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Denomination of invention: Application of a small molecular active peptide in inducing differentiation of hUC-MSCs Effective date of registration: 20230103 Granted publication date: 20220809 Pledgee: Linyi County sub branch of Postal Savings Bank of China Ltd. Pledgor: DEZHOU LANLI BIOLOGICAL TECHNOLOGY Co.,Ltd. Registration number: Y2022980030070 |
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