CN112472979A - Micro-administration equipment for infants - Google Patents

Micro-administration equipment for infants Download PDF

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Publication number
CN112472979A
CN112472979A CN202011396663.1A CN202011396663A CN112472979A CN 112472979 A CN112472979 A CN 112472979A CN 202011396663 A CN202011396663 A CN 202011396663A CN 112472979 A CN112472979 A CN 112472979A
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CN
China
Prior art keywords
micro
liquid supply
medicine
supply passage
infant
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Pending
Application number
CN202011396663.1A
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Chinese (zh)
Inventor
王贞
王晓蕾
李小梅
蓓龚春
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Nanfang Hospital
First Affiliated Hospital of PLA Military Medical University
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First Affiliated Hospital of PLA Military Medical University
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Application filed by First Affiliated Hospital of PLA Military Medical University filed Critical First Affiliated Hospital of PLA Military Medical University
Priority to CN202011396663.1A priority Critical patent/CN112472979A/en
Publication of CN112472979A publication Critical patent/CN112472979A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0618Nose

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention relates to a micro-dosing device for infants, belonging to the technical field of medical instruments, comprising an injection needle, a liquid supply passage, a constant speed mechanism, a quantitative mechanism and a medicine storage box arranged at the end part of the liquid supply passage, wherein the constant speed mechanism comprises a micro peristaltic pump, the quantitative mechanism comprises a micro flow meter, an electromagnetic switch valve and a processor, the medicine storage box is provided with a dosing port and a liquid supply port, the liquid supply port is communicated with the liquid supply passage, the dosing port is arranged at the top of the medicine storage box and is sealed and fixed by a sealing cover, the injection needle comprises a connecting end, a dosing end and a bending adjusting part, and the dosing end is provided with a plurality of micro holes. The invention improves the reliability and safety of nasal administration by micro-precise control of the dosage and the flow rate, and makes the rapid development of the nasal administration possible; manual operation is replaced by mechanical operation, so that the productivity is liberated; and the liquid supply box can work uninterruptedly, so that a plurality of people can sequentially administer the medicine, and the productivity is further liberated.

Description

Micro-administration equipment for infants
Technical Field
The invention relates to the technical field of medical instruments, in particular to equipment for micro-administration of medicines such as sedatives and the like to nasal cavities of infants.
Background
Infants need to be administered via the nasal cavity for many reasons, such as examination, nasal congestion, surgery, etc. For example, to examine the eyes, a minute amount of sedative, such as dexmedetomidine hydrochloride in an amount of about 1ml, is injected to help the infant sleep; in addition, after nasal obstruction, the anti-inflammatory drug is sprayed to lead the nasal mucosa to astringe and ventilate; in addition, for example, local anesthesia in clinical operation, local anesthetic with high permeability needs to be contacted with local mucosa to penetrate through the mucosa and act on nerve endings to generate anesthesia.
In the prior art, the injection needle is used for directly injecting the medicine, so that the flow rate of the medicine is not monitored, the flow rate of the medicine is too high, the absorption and expected effect are influenced, the nasal cavity is blocked and the air is blocked, and the danger is caused; on one hand, the medicine amount is not monitored, so that waste is possibly caused, or the medicine amount is insufficient; on the other hand, the injection process needs manual operation, occupies a large amount of medical care time, influences the medical care efficiency and causes psychological stress. In addition, the injection needle is a steel needle, has no bending deformation capability, cannot conform to the nasal cavity of a human body, and can damage the nasal mucosa due to improper operation.
Therefore, the prior art does not have a better solution for nasal administration of infants, influences the reliability and safety of nasal administration, and restricts the development of nasal administration. A brand-new drug delivery device is needed, on one hand, the flow rate of the drug can be controlled, the absorption effect is ensured, and the safety risk is reduced; on the other hand, the dosage of the medicine can be controlled, so that the treatment effect is ensured; more importantly, micro-regulation and continuous administration are required.
Disclosure of Invention
In view of this, the present invention provides an infant micro-drug delivery device, which can perform micro-control and continuous multi-person sequential drug delivery, so as to solve the problems in the prior art that the drug flow and the dose cannot be accurately controlled by manual operation, so that the desired target cannot be achieved, and the safety risk and the operation efficiency are low.
The invention is realized by the following technical scheme:
the micro-dosing equipment for the infants comprises an injection needle, a liquid supply passage, a constant speed mechanism, a quantitative mechanism and a medicine storage box arranged at the end part of the liquid supply passage, wherein the constant speed mechanism comprises a micro peristaltic pump arranged on the liquid supply passage, the quantitative mechanism comprises a micro flow meter and an electromagnetic switch valve which are arranged on the liquid supply passage, and a processor which is arranged outside the passage and is electrically communicated with the electromagnetic switch valve and the micro flow meter, the medicine storage box is provided with a medicine feeding port and a liquid feeding port, the liquid feeding port is communicated with the liquid supply passage, the medicine feeding port is arranged at the top of the medicine storage box and is sealed and fixed by a sealing cover, the injection needle comprises a connecting end connected with the liquid supply passage, a dosing end used for granulating liquid medicine and a bending adjusting part arranged between the connecting end and the dosing end, and the connecting end, the bending adjusting part and the dosing end are all provided with a medicine, the administration end is provided with a plurality of micro holes for atomizing the medicament, and the micro holes are communicated with the medicament passage.
Furthermore, the outside of the administration end is provided with a plurality of miniature pressure sensors for detecting contact pressure, and the miniature pressure sensors are electrically communicated with the processor.
Furthermore, an operating handle is fixedly arranged on a liquid supply passage between the micro peristaltic pump and the electromagnetic switch valve, and a micro vibration motor electrically communicated with the processor is arranged in the operating handle.
Further, a liquid supply passage between the micro peristaltic pump and the medicine supply box is provided with a switch valve.
Further, still include the display, the display setting is at miniature peristaltic pump top, display and treater electrical communication.
Further, the liquid supply passage is a rubber hose.
Further, a fixing frame is arranged on the side face of the micro peristaltic pump, and the liquid supply tank is detachably fixed on the fixing frame.
Further, the bending regulating portion is made of a corrugated tube.
The invention has the beneficial effects that:
1. according to the invention, by the flow rate control of the micro peristaltic pump and the supervision of the processor, a micro and constant injection speed is provided, the flow rate can be controlled to be 0.0015-380 ml/min, the accurate control of the injection flow rate is realized, the absorption effect of infant drug administration is ensured, accidents such as air lock and the like are prevented, and the safety risk is reduced;
2. according to the invention, the flow of ml level can be accurately controlled by the combined scheme of the micro-flowmeter, the electromagnetic switch valve and the processor, so that the total drug delivery amount can be accurately controlled, and the treatment effect is ensured;
3. the shape of the injection needle can be adjusted by bending the adjusting part to adapt to the shape of the nasal cavity, so that the damage caused by pressing the nasal mucosa is avoided, the safety is improved, the operation comfort is easy to keep, and the acceptability of infants is improved;
4. the medicine is subjected to multi-hole atomization, so that the medicine is administered in multiple points, the administration area is enlarged, the medicine receiving level is improved, and the medicine effect is better;
5. the invention can replace the traditional manual operation with the mechanical operation by combining the constant speed mechanism and the quantitative mechanism, thereby reducing the labor intensity, improving the operation efficiency and freeing the medical care personnel from the heavy work.
In a word, the invention improves the reliability and safety of nasal administration by micro-precise control of the dose and the flow rate, makes the rapid development of nasal administration possible, and replaces manual operation by mechanical operation, thereby liberating productivity.
Additional advantages, objects, and features of the invention will be set forth in part in the description which follows and in part will become apparent to those having ordinary skill in the art upon examination of the following or may be learned from practice of the invention. The objectives and other advantages of the invention may be realized and attained by the means of the instrumentalities and combinations particularly pointed out hereinafter.
Drawings
FIG. 1 is a three-dimensional schematic view of a first perspective of the present invention;
FIG. 2 is a three-dimensional schematic view of a second perspective of the present invention;
fig. 3 is a schematic view of the structure of the injection needle.
In the figure: 1-a medicine storage box; 2-injection needle; 3-a liquid supply passage; 4-a constant speed mechanism; 5-a dosing mechanism; 6-micro peristaltic pump; 7-a micro flow meter; 8-an electromagnetic switch valve; 9-a processor; 10-an administration port; 11-a liquid supply port; 12-a sealing cover; 13-a connection end; 14-administration end; 15-a bending adjustment section; 16-a micro-well; 17-a miniature pressure sensor; 18-an operating handle; 19-a miniature vibration motor; 20-a switch valve; 21-a display; 22-fixing frame.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the above description of the present invention, it should be noted that the terms "one side", "the other side" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings or orientations or positional relationships that the products of the present invention are conventionally placed in use, and are only used for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the device or the element to which the present invention is directed must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like are used merely to distinguish one description from another, and are not to be construed as indicating or implying relative importance.
Further, the term "identical" and the like do not mean that the components are absolutely required to be identical, but may have slight differences. The term "perpendicular" merely means that the positional relationship between the components is more perpendicular than "parallel", and does not mean that the structure must be perfectly perpendicular, but may be slightly inclined.
Referring to fig. 1-3, the present invention provides a technical solution: the infant micro-dosing equipment comprises a medicine storage box 1, an injection needle 2, a liquid supply passage 3, a constant speed mechanism 4 and a quantitative mechanism 5, wherein the liquid supply passage can be a rubber hose, the medicine storage box is arranged at one end of the rubber hose, the other end of the medicine storage box is communicated with the injection needle, and medicines enter the liquid supply passage through the medicine storage box and then enter the injection needle to provide medicines for a nasal cavity; the constant speed mechanism of the embodiment comprises a micro peristaltic pump 6, the micro peristaltic pump acts on a rubber hose, the rubber hose can be extruded to form driving force, liquid medicine is driven to flow, and medicine administration is completed, the type and specification of the micro peristaltic pump are not limited, only the constant driving force is required to be provided, for example, a BT100MH digital rotating speed type peristaltic pump is adopted, the flow rate is 0.0015-380 ml/min, the proper flow rate can be selected for working, the flow rate of the embodiment can be 1ml/min, and the constant speed medicine administration is realized, the quantitative mechanism of the embodiment comprises a micro flow meter 7 and an electromagnetic switch valve 8 which are arranged on a liquid supply passage, a processor 9 which is arranged outside the passage and is electrically communicated with the electromagnetic switch valve and the micro flow meter, a total flow rate value is set through the processor, the micro flow meter monitors the flow rate, and transmits flow rate information to the processor through a, the processor compares the set value, and sends an electric signal to close the electromagnetic switch valve when the set value is reached, so that the medicine supply is stopped; the model and specification of the micro-flowmeter are not limited, a proper flowmeter can be selected according to actual needs, the total amount of the liquid medicine to be controlled is 1ml in the embodiment, a small metal tube rotameter can be selected, and the minimum measurable flow range is as follows: 0.1to 1 l/h; the medicine storage box of the embodiment is provided with a medicine feeding port 10 and a liquid feeding port 11, the liquid feeding port is communicated with a rubber hose, the medicine feeding port is arranged at the top of the medicine storage box and is sealed and fixed by a sealing cover 12; specifically, the injection needle comprises a connecting end 13 connected with the liquid supply passage, a drug administration end 14 for granulating the drug solution, and a bending adjustment part 15 arranged between the connecting end and the drug administration end, wherein the connecting end, the bending adjustment part and the drug administration end are all provided with drug passages communicated with the liquid supply passage, the drug administration end is provided with a plurality of micro holes 16 for atomizing the drug, and the micro holes are communicated with the drug passages. Due to the existence of the bent adjusting part, the shape of the injection needle can be adjusted to adapt to the shape of the nasal cavity, the damage caused by pressing the nasal mucosa is avoided, the safety is improved, the comfort of operation is easy to keep, and the acceptability of infants is improved. The liquid medicine can be dispersed through the atomization of the micro-holes, and the administration area is enlarged.
Compared with the prior art, the embodiment has the following advantages:
1. the micro and constant injection speed is provided by the flow rate control of the micro peristaltic pump and the supervision of the processor, the flow can be controlled within 1ml/min, the accurate control of the injection flow is realized, the absorption effect of the infant drug administration is ensured, accidents such as gas blockage are prevented, and the safety risk is reduced;
2. the flow of ml level can be accurately controlled by the combined scheme of the micro-flowmeter, the electromagnetic switch valve and the processor, so that the total drug delivery amount can be accurately controlled, and the treatment effect is ensured;
3. the shape of the injection needle can be adjusted by bending the adjusting part to adapt to the shape of the nasal cavity, so that the damage caused by pressing the nasal mucosa is avoided, the safety is improved, the operation comfort is easy to keep, and the acceptability of infants is improved;
4. the medicine is subjected to multi-hole atomization, so that the medicine is administered in multiple points, the administration area is enlarged, the medicine receiving level is improved, and the medicine effect is better;
5. through the combined use of the constant speed mechanism and the quantitative mechanism, the traditional manual operation can be replaced by the mechanical operation, the labor intensity is reduced, the operation efficiency is improved, and the medical care personnel are liberated from heavy work.
In a word, the embodiment improves the reliability and safety of nasal administration by micro-precise control of the dose and the flow rate, enables the rapid development of nasal administration to be possible, replaces manual operation by mechanical operation, and liberates productivity.
As a modification of this embodiment, a plurality of micro pressure sensors 17 for detecting contact pressure are provided outside the administration end, and the plurality of micro pressure sensors are in electrical communication with the processor. The type and specification of the miniature pressure sensor are not limited, and a soft contact sensor made of a nanofiber composite material consisting of carbon nanotubes and graphene can be selected; a CYG502 type ultra-micro pressure sensor can be selected; a nanoscale pressure sensor may be selected. Whichever is chosen, the objective is to detect the contact pressure of the outer surface of the administration end in response to contact and formation of pressure against the nasal cavity wall, thereby avoiding damage to the mucosa.
The detection process is the same as the constant speed, the micro pressure sensor receives the pressure signal firstly, then the pressure signal is transmitted to the processor, the processor can determine whether the pressure signal is abnormal or not by comparing the set value, and if the pressure signal is abnormal, the processor prompts an operator to stop the action and checks whether the contact action exists or not. The prompting means may be a vibration motion or a video signal or an audio signal. The embodiment preferably adopts a vibration action, specifically:
an operating handle 18 is fixedly arranged on a liquid supply passage between the micro peristaltic pump and the electromagnetic switch valve, and a micro vibration motor 19 electrically communicated with the processor is arranged in the operating handle. When the processor determines that the pressure value exceeds the set value, an alarm signal is sent out, the micro vibration motor is communicated, and the micro vibration motor is enabled to send out vibration action, so that the alarm is realized. The vibration sensing device is arranged at the operating handle and is in contact with the hand of an operator, so that the vibration signal can be sensed easily.
As a modification of the embodiment, a switch valve 20 is arranged on a liquid supply passage between the micro peristaltic pump and the medicine supply box. The medicine path can be closed, and the operations of replacement, maintenance and the like of the rear end part are facilitated.
As a modification of this embodiment, the device further comprises a display 21, the display is arranged on the top of the micro peristaltic pump, and the display is electrically communicated with the processor. The accessible display is to the demonstration of testing result, makes medical personnel master pressure, velocity of flow and flow information in real time to make timely operation, make the operation of dosing visual, accurate and safer.
As the improvement of this embodiment, the side of miniature peristaltic pump is provided with mount 22, and the mount is L type structure, and the one end and the miniature peristaltic pump of L are connected, and the other end is connected with the feed tank, and both can dismantle the connection, for example screw or bolted connection, conveniently change, and do benefit to warehousing and transportation.
As a modification of this embodiment, the bending adjustment part is made of a corrugated tube so that it can be bent as required.
Finally, the above embodiments are only for illustrating the technical solutions of the present invention and not for limiting, although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all of them should be covered in the claims of the present invention.

Claims (8)

1. Infant dosing apparatus comprising an injection needle and a liquid supply path, characterized in that: the constant-speed mechanism comprises a micro peristaltic pump arranged on the liquid supply passage, the quantifying mechanism comprises a micro flow meter and an electromagnetic switch valve which are arranged on the liquid supply passage, and a processor which is arranged outside the passage and is electrically communicated with the electromagnetic switch valve and the micro flow meter, the medicine storage box is provided with a medicine feeding port and a liquid feeding port, the liquid feeding port is communicated with the liquid supply passage, the medicine feeding port is arranged at the top of the medicine storage box and is sealed and fixed by a sealing cover, the injection needle comprises a connecting end connected with the liquid supply passage, a medicine feeding end used for granulating the liquid medicine and a bending adjusting portion arranged between the connecting end and the medicine feeding end, the connecting end, the bending adjusting portion and the medicine feeding end are respectively provided with a medicine passage communicated with the liquid supply passage, and the medicine feeding end is provided with a plurality of micro holes used for atomizing the medicine, the micro-holes communicate with the drug passageway.
2. An infant micro dosing device as claimed in claim 1, wherein: the outside of the administration end is provided with a plurality of miniature pressure sensors for detecting contact pressure, and the miniature pressure sensors are electrically communicated with the processor.
3. An infant micro dosing device as claimed in claim 2, wherein: an operating handle is fixedly arranged on a liquid supply passage between the micro peristaltic pump and the electromagnetic switch valve, and a micro vibration motor electrically communicated with the processor is arranged in the operating handle.
4. An infant micro dosing device as claimed in claim 1, wherein: and a switching valve is arranged on a liquid supply passage between the micro peristaltic pump and the medicine supply box.
5. An infant micro dosing device as claimed in claim 1, wherein: still include the display, the display setting is at miniature peristaltic pump top, display and treater electrical communication.
6. An infant micro dosing device as claimed in claim 1, wherein: the liquid supply passage is a rubber hose.
7. An infant micro dosing device as claimed in claim 1, wherein: the side of the micro peristaltic pump is provided with a fixing frame, and the liquid supply tank is detachably fixed on the fixing frame.
8. An infant micro dosing device as claimed in claim 1, wherein: the bending adjustment portion is made of a corrugated tube.
CN202011396663.1A 2020-12-02 2020-12-02 Micro-administration equipment for infants Pending CN112472979A (en)

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CN202011396663.1A CN112472979A (en) 2020-12-02 2020-12-02 Micro-administration equipment for infants

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Application Number Priority Date Filing Date Title
CN202011396663.1A CN112472979A (en) 2020-12-02 2020-12-02 Micro-administration equipment for infants

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113730779A (en) * 2021-11-05 2021-12-03 纳索菲德(上海)制药技术有限公司 Device for spraying medicine to nasal cavity and using method

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CN209286316U (en) * 2018-07-26 2019-08-23 田晓娜 A kind of Gynecological washing device
CN110314273A (en) * 2019-07-09 2019-10-11 自贡市第四人民医院(自贡市急救中心) A kind of supra-aural intranasal medicator and medication
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CN101961519A (en) * 2004-08-31 2011-02-02 伊西康内外科公司 Medical effector subsystem and a drug delivery pump sub-component
CN203030445U (en) * 2013-01-11 2013-07-03 浙江康是医疗器械有限公司 Quantitative atomization device for liquid medicines
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CN205127004U (en) * 2015-11-17 2016-04-06 王谦 Special micro - quantitative transfer pump of paediatrics nursing
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CN208355920U (en) * 2017-06-30 2019-01-11 宁夏佑安医疗器械有限公司 Public's hand disinfection intelligent terminal
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113730779A (en) * 2021-11-05 2021-12-03 纳索菲德(上海)制药技术有限公司 Device for spraying medicine to nasal cavity and using method

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