CN112471504A - Special medical purpose formula food for epileptic and preparation method thereof - Google Patents

Special medical purpose formula food for epileptic and preparation method thereof Download PDF

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Publication number
CN112471504A
CN112471504A CN202011470834.0A CN202011470834A CN112471504A CN 112471504 A CN112471504 A CN 112471504A CN 202011470834 A CN202011470834 A CN 202011470834A CN 112471504 A CN112471504 A CN 112471504A
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oil
epileptic
special medical
formula food
powder
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王元秀
李旭
丁良
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University of Jinan
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pediatric Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention provides a special medical application formula food for epileptics and a preparation method thereof, wherein each 100g of the special medical application formula food for epileptics contains: 10-20g of concentrated whey protein, 11-18g of soybean protein isolate, 10-20g of medium-chain fatty acid, 5-11g of vegetable oil powder, 18-30g of fish oil powder, 2-8g of fructo-oligosaccharide, 10-16g of maltodextrin, 0.01-0.5g of tryptophan, 3-8g of mineral premix and 0.05-0.15g of vitamin premix, and the components are uniformly mixed to prepare the finished product. The invention utilizes the metabolism of amino acid in vivo to relieve oxidative stress and prolong the epileptic seizure period of patients through the synergistic effect of various components.

Description

Special medical purpose formula food for epileptic and preparation method thereof
Technical Field
The invention relates to a nutritional preparation, in particular to a special medical application formula food for epileptics and a preparation method thereof, belonging to the technical field of biology.
Background
Epilepsy is a chronic nervous system disease, at present, the epileptic seizure of most patients can be controlled by medication, but some patients have poor response to the anti-epileptic medication, and the epileptic seizure is difficult to control, so that intractable epilepsy is formed. At present, more than 600 million epileptics in China are present, 65-70 million new epileptics are present each year, and about 25 percent of patients are intractable epileptics. Although the current diagnosis and treatment of epilepsy has advanced greatly, the number of intractable epilepsy patients is increasing.
In 2009, Fretias et al (Fretias R M D, Nasciento K G D, Ferreira P, et al, Neurochemical change on oxidative stress in a thioppocampus duringphase of pirocarpine-induced epilepsy [ J ]. Pharmacology Biochemistry and Behavior 2010, 94: 341-345.) demonstrated by rat experiments that oxidative stress plays an important role in the onset of epilepsy and that the duration of epilepsy was positively correlated with oxidative damage.
Tryptophan can relieve oxidative stress (NAYAK B N, BUTTAR H S. Evaluation of the antioxidant properties of tryptophans and its metabolites in the vitamin assay [ J ]. Journal of Complementary and integral Medicine, 2016, 13: 129-136.), the oxidative stress can enhance the catabolism of tryptophan, the amino group of tryptophan can be directly combined with an oxidizing agent, the oxidation reaction of other substances can be effectively prevented, and the antioxidant effect can be achieved. Melatonin, a metabolite of tryptophan, acts as a non-enzymatic antioxidant to scavenge free radicals in the body and also has antioxidant activity. At present, no nutritional functional food aiming at intractable epileptics exists in the market and literature reports.
Disclosure of Invention
The invention provides a special medical application formula food for epileptics and a preparation method thereof, aiming at prolonging the epileptic seizure period of patients by utilizing the influence of the metabolism of amino acid in vivo on oxidative stress.
The invention provides a special medical application formula food for epileptics, which is powder and is prepared by the following steps.
Formula food compound with special medical application
The formula food for the special medical application of the epileptic contains per 100 g:
10-20g of concentrated whey protein,
11-18g of the isolated soy protein,
10-20g of medium-chain fatty acid,
5-11g of vegetable oil powder,
18-30g of fish oil powder,
2-8g of fructo-oligosaccharide,
10-16g of maltodextrin, namely 10-16g,
0.01-0.5g of tryptophan,
3-8g of mineral premix, and the like,
0.05-0.15g of vitamin premix.
The vegetable oil powder is prepared from vegetable oil and edible carrier at a weight ratio of (40-50) to (40-50) by mixing vegetable oil and edible carrier, and spray drying to obtain powder.
The vegetable oil can be one or more of peanut oil, soybean oil, linseed oil, cottonseed oil, castor oil, rapeseed oil, sesame oil, olive oil, tea oil and the like.
The fish oil powder is prepared from fish oil and edible carrier at a weight ratio of (40-50) to (40-50), by mixing the fish oil and the edible carrier, and spray drying to obtain powder.
The edible carrier is maltodextrin.
Each gram of the mineral premix comprises 30-80 mg of calcium carbonate, 15-20 mg of magnesium chloride, 50-100 mg of edible salt, 80-150 mg of potassium chloride, 20-60 mg of monopotassium phosphate, 0.5-1.0 mg of ferrous sulfate monohydrate, 0.2-0.6 mg of zinc sulfate monohydrate, 0.001-0.01 mg of sodium selenite, 0.03-0.06 mg of anhydrous copper sulfate, 0.01-0.05 mg of manganese citrate, 0.005-0.01 mg of potassium iodide and the balance of mineral premix carrier.
The mineral premix carrier is maltodextrin.
Each gram of the vitamin premix comprises 2-5 mg of vitamin A, 0.03-0.06 mg of vitamin D, 500 mg of ascorbic acid 250-one, 30-60 mg of vitamin E, 10.1-0.5 mg of vitamin K, 3-6 mg of thiamine, 2-6 mg of riboflavin, 8-15 mg of nicotinamide, 15-20 mg of pantothenic acid, 3-6 mg of pyridoxine hydrochloride, 0.5-2.5 mg of folic acid, 0. 120.003-0.020 mg of vitamin B, 0.05-0.25 mg of biotin and the balance of vitamin premix carrier.
The vitamin premix carrier is maltodextrin.
② mixing the formula food with special medical application
Crushing the weighed nutrients, sieving with a 100-mesh sieve, and mixing and uniformly mixing by using a mixer.
The special medical formula food for the epileptics provided by the invention has the advantages of prolonging the seizure time of the epileptics, reducing the oxidative stress in the body of the epileptics and relieving the epileptics.
The formula food for the special medical application of the epileptic provided by the invention contains proteins such as soybean protein isolate and concentrated whey protein, has rich nitrogen source, better supplements the required protein, is rich in unsaturated fatty acids such as medium-chain fatty acid and DHA, and has important inhibiting effect on oxidative stress of the epileptic.
The formula food for the special medical application of the epileptic provided by the invention is particularly added with tryptophan, which is beneficial to relieving the oxidative stress of the epileptic and improving the immunity of the epileptic.
The special medical formula food for the epileptic provided by the invention adopts maltodextrin and other low GI carbohydrates, and is beneficial to controlling the blood sugar of the epileptic.
The formula food for the special medical application of the epileptic provided by the invention is a compound food, combines proteins such as soybean protein isolate, concentrated whey protein and the like, supplements required proteins, combines tryptophan to relieve the oxidative stress of the epileptic, combines low-GI carbohydrate such as maltodextrin to control the blood sugar of the patient, relieves the oxidative stress of the epileptic through the synergistic effect of various components, improves the immunity of the patient, and relieves the attack of the epileptic. The special medical purpose formula food for the epileptic can be used as a nutritional food for providing nutritional support for intractable epileptic, and can also be used as nutritional support for common epileptic.
Example 1:
formula food compound with special medical application
The formula food for the special medical application of the epileptic contains per 100 g:
14.34 g of concentrated whey protein is added,
14.43 g of the isolated soy protein,
15.15 g of medium-chain fatty acid,
8.31 g of vegetable oil powder,
23.46 g of fish oil powder,
5.06 g of fructo-oligosaccharide,
13.09 g of the maltodextrin, namely 13.09 g,
0.19 g of tryptophan (tryptophan) is added,
5.87 g of mineral premix, namely,
0.10 g of vitamin premix;
② mixing the formula food with special medical application
Crushing the weighed nutrients, sieving with a 100-mesh sieve, and mixing uniformly by using a mixer;
the vegetable oil powder consists of vegetable oil and maltodextrin in a weight ratio of 1:1, and is prepared by mixing the vegetable oil and the maltodextrin, and performing spray drying to prepare powder;
the vegetable oil can be one or more of peanut oil, soybean oil, linseed oil, cottonseed oil, castor oil, rapeseed oil, sesame oil, olive oil, tea oil and the like;
the fish oil powder consists of fish oil and maltodextrin in a weight ratio of 1:1, and is prepared by mixing the fish oil and the maltodextrin, and performing spray drying on the mixture to prepare powder;
each gram of the mineral premix comprises 56 mg of calcium carbonate, 18.3 mg of magnesium chloride, 83 mg of edible salt, 111 mg of potassium chloride, 40 mg of monopotassium phosphate, 0.83 mg of ferrous sulfate monohydrate, 0.4 mg of zinc sulfate monohydrate, 0.003 mg of sodium selenite, 0.044 mg of anhydrous copper sulfate, 0.025 mg of manganese citrate, 0.007 mg of potassium iodide and the balance of maltodextrin;
each gram of the vitamin premix comprises 3.6 mg of vitamin A, 0.048 mg of vitamin D, 336 mg of ascorbic acid, 48 mg of vitamin E, 10.264 mg of vitamin K, 4.2 mg of thiamine, 4.2 mg of riboflavin, 12 mg of nicotinamide, 17.4 mg of pantothenic acid, 4.2 mg of pyridoxine hydrochloride, 1.332 mg of folic acid, 120.0078 mg of vitamin B, 0.132 mg of biotin and the balance of maltodextrin.
Example 2:
formula food compound with special medical application
The formula food for the special medical application of the epileptic contains per 100 g:
10 g of concentrated whey protein is added into the concentrated whey protein,
14 g of the isolated soy protein (soy protein),
20g of medium-chain fatty acid,
6g of vegetable oil powder is prepared by mixing vegetable oil powder,
21.4 g of fish oil powder,
6g of fructo-oligosaccharide,
14.45 g of maltodextrin, namely 14.45 g,
0.1 g of tryptophan is added in the feed,
8g of mineral premix, namely 8g of mineral premix,
0.05 g of vitamin premix;
② mixing the formula food with special medical application
Crushing the weighed nutrients, sieving with a 100-mesh sieve, and mixing uniformly by using a mixer;
the vegetable oil powder consists of vegetable oil and maltodextrin in a weight ratio of 1:1, and is prepared by mixing the vegetable oil and the maltodextrin, and performing spray drying to prepare powder;
the vegetable oil can be one or more of peanut oil, soybean oil, linseed oil, cottonseed oil, castor oil, rapeseed oil, sesame oil, olive oil, tea oil and the like;
the fish oil powder consists of fish oil and maltodextrin in a weight ratio of 1:1, and is prepared by mixing the fish oil and the maltodextrin, and performing spray drying on the mixture to prepare powder;
each gram of the mineral premix comprises 56 mg of calcium carbonate, 18.3 mg of magnesium chloride, 83 mg of edible salt, 111 mg of potassium chloride, 40 mg of monopotassium phosphate, 0.83 mg of ferrous sulfate monohydrate, 0.4 mg of zinc sulfate monohydrate, 0.003 mg of sodium selenite, 0.044 mg of anhydrous copper sulfate, 0.025 mg of manganese citrate, 0.007 mg of potassium iodide and the balance of maltodextrin;
each gram of the vitamin premix comprises 3.6 mg of vitamin A, 0.048 mg of vitamin D, 336 mg of ascorbic acid, 48 mg of vitamin E, 10.264 mg of vitamin K, 4.2 mg of thiamine, 4.2 mg of riboflavin, 12 mg of nicotinamide, 17.4 mg of pantothenic acid, 4.2 mg of pyridoxine hydrochloride, 1.332 mg of folic acid, 120.0078 mg of vitamin B, 0.132 mg of biotin and the balance of maltodextrin.
Example 3:
formula food compound with special medical application
The formula food for the special medical application of the epileptic contains per 100 g:
20g of concentrated whey protein is added into the milk,
10 g of the isolated soy protein is extracted from the soybean,
10 g of medium-chain fatty acid,
10 g of the vegetable oil powder is added,
28 g of fish oil powder is prepared by grinding the fish oil,
2.6 g of fructo-oligosaccharide,
16g of maltodextrin, namely 16g of maltodextrin,
0.25 g of tryptophan was added thereto,
3 g of mineral premix, namely 3 g of mineral premix,
0.15g of vitamin premix;
② mixing the formula food with special medical application
Crushing the weighed nutrients, sieving with a 100-mesh sieve, and mixing uniformly by using a mixer;
the vegetable oil powder consists of vegetable oil and maltodextrin in a weight ratio of 1:1, and is prepared by mixing the vegetable oil and the maltodextrin, and performing spray drying to prepare powder;
the vegetable oil can be one or more of peanut oil, soybean oil, linseed oil, cottonseed oil, castor oil, rapeseed oil, sesame oil, olive oil, tea oil and the like;
the fish oil powder consists of fish oil and maltodextrin in a weight ratio of 1:1, and is prepared by mixing the fish oil and the maltodextrin, and performing spray drying on the mixture to prepare powder;
each gram of the mineral premix comprises 56 mg of calcium carbonate, 18.3 mg of magnesium chloride, 83 mg of edible salt, 111 mg of potassium chloride, 40 mg of monopotassium phosphate, 0.83 mg of ferrous sulfate monohydrate, 0.4 mg of zinc sulfate monohydrate, 0.003 mg of sodium selenite, 0.044 mg of anhydrous copper sulfate, 0.025 mg of manganese citrate, 0.007 mg of potassium iodide and the balance of maltodextrin;
each gram of the vitamin premix comprises 3.6 mg of vitamin A, 0.048 mg of vitamin D, 336 mg of ascorbic acid, 48 mg of vitamin E, 10.264 mg of vitamin K, 4.2 mg of thiamine, 4.2 mg of riboflavin, 12 mg of nicotinamide, 17.4 mg of pantothenic acid, 4.2 mg of pyridoxine hydrochloride, 1.332 mg of folic acid, 120.0078 mg of vitamin B, 0.132 mg of biotin and the balance of maltodextrin.
The invention provides the influence of the formula food for the special medical application of the epileptic patient on the epileptic attack of the mice:
constructing an epilepsia mouse model, taking the test of the example 1-3, only irrigating the stomach, setting a negative control group at the same time, irrigating the stomach with physiological saline of the negative control group, and normally feeding. Kunming mice, male, weight 18-22 g, each group of 10. Mice were gavaged daily for 4 weeks at a dose of 0.05 g/10 g. Weighing 1 time every day, observing the disease condition, taking blood from eyeball after last gastric lavage for 1 h, and detecting malondialdehyde content and enzyme activities of superoxide dismutase, glutathione peroxidase and SOD with malondialdehyde detection kit (Nanjing institute of bioengineering), superoxide dismutase detection kit (Nanjing institute of bioengineering), glutathione peroxidase detection kit (Nanjing institute of bioengineering), and SOD commercial detection kit (Biyuntian). The results of the influence of the formula food for special medical application of epileptics on the body weight of a mouse are shown in table 1, the results of the influence on the attack of epilepsy are shown in table 2, and the influences on the malonaldehyde content and the enzyme activity are shown in table 3.
TABLE 1 Effect of formula foods for specific medical uses on body weight of mice in epileptic patients
Figure 465603DEST_PATH_IMAGE002
As can be seen from Table 1, there was no significant difference in the weight gain (P > 0.05) in the mice of examples 1-3, compared to the negative control group. Therefore, the preparation has no obvious influence on the weight increase of mice, and can maintain the normal physiological function of the mice.
TABLE 2 influence of formula food for special medical use of epileptic on onset of epilepsy in mice
Figure 943596DEST_PATH_IMAGE004
As can be seen from Table 2, the formula food for the special medical use of the epileptic provided by the invention can obviously prolong the epileptic seizure period of mice and is beneficial to relieving epilepsy.
TABLE 3 influence of formula food for special medical use on blood index of mouse for epileptic
Figure 785650DEST_PATH_IMAGE006
As can be seen from Table 3, the formula food for the special medical application of the epileptic provided by the invention can improve the enzyme activities of superoxide dismutase, glutathione peroxidase and SOD and reduce the content of malondialdehyde relative to a negative control group, and can relieve the epilepsy of mice.

Claims (8)

1. Formula food compound with special medical application
The formula food for the special medical application of the epileptic contains per 100 g:
10-20g of concentrated whey protein,
11-18g of the isolated soy protein,
10-20g of medium-chain fatty acid,
5-11g of vegetable oil powder,
18-30g of fish oil powder,
2-8g of fructo-oligosaccharide,
10-16g of maltodextrin, namely 10-16g,
0.01-0.5g of tryptophan,
3-8g of mineral premix, and the like,
0.05-0.15g of vitamin premix;
② mixing the formula food with special medical application
Crushing the weighed nutrients, sieving with a 100-mesh sieve, and mixing and uniformly mixing by using a mixer.
2. The food formulation for specific medical use of epileptic as claimed in claim 1, wherein said vegetable oil powder is composed of vegetable oil and edible carrier at a weight ratio of (40-50) to (40-50), and is obtained by mixing vegetable oil and edible carrier, spray drying to obtain powder.
3. The special medical formula food for epileptic according to claim 2, wherein said vegetable oil may be one or more of peanut oil, soybean oil, linseed oil, cottonseed oil, castor oil, rapeseed oil, sesame oil, olive oil, tea oil, etc.
4. The special medical formula food for epileptic according to claim 1, wherein the fish oil powder is composed of fish oil and edible carrier at a weight ratio of (40-50) to (40-50), and the fish oil powder is obtained by mixing the fish oil and the edible carrier, and spray-drying the mixture to obtain powder.
5. The epileptic specific medical use formula of claims 2-3, wherein the edible carrier is maltodextrin.
6. The formula food for special medical application of epileptic according to claim 1, wherein each 1g of the mineral premix comprises 30-80 mg of calcium carbonate, 15-20 mg of magnesium chloride, 50-100 mg of edible salt, 80-150 mg of potassium chloride, 20-60 mg of monopotassium phosphate, 0.5-1.0 mg of ferrous sulfate monohydrate, 0.2-0.6 mg of zinc sulfate monohydrate, 0.001-0.01 mg of sodium selenite, 0.03-0.06 mg of anhydrous copper sulfate, 0.01-0.05 mg of manganese citrate, 0.005-0.01 mg of potassium iodide and the balance of mineral premix carrier.
7. The special medical application formula food for the epileptic according to claim 1, wherein each 1g of the mineral premix comprises 50-60 mg of calcium carbonate, 18-19 mg of magnesium chloride, 80-90 mg of edible salt, 120 mg of potassium chloride 100-.
8. The epileptic specific medical use formula according to claims 6-7, wherein the premix carrier is maltodextrin.
CN202011470834.0A 2020-12-15 2020-12-15 Special medical purpose formula food for epileptic and preparation method thereof Withdrawn CN112471504A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114601172A (en) * 2022-03-10 2022-06-10 山东若尧特医食品有限公司 Formula food of glutamine composition with special medical application and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104082739A (en) * 2014-06-24 2014-10-08 广州纽健生物科技有限公司 Comprehensive nutritional and semi-digested formulated food for special medical use, and preparation method thereof
CN108077911A (en) * 2017-12-13 2018-05-29 上海奥医生物医药科技有限公司 A kind of epileptic's tailored version clinical nutrition formula and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104082739A (en) * 2014-06-24 2014-10-08 广州纽健生物科技有限公司 Comprehensive nutritional and semi-digested formulated food for special medical use, and preparation method thereof
CN108077911A (en) * 2017-12-13 2018-05-29 上海奥医生物医药科技有限公司 A kind of epileptic's tailored version clinical nutrition formula and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114601172A (en) * 2022-03-10 2022-06-10 山东若尧特医食品有限公司 Formula food of glutamine composition with special medical application and preparation method thereof
CN114601172B (en) * 2022-03-10 2024-03-19 山东若尧特医食品有限公司 Formula food with special medical application of glutamine composition and preparation method thereof

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Application publication date: 20210312