CN112300267A - 一种重组人胰岛素的制备和纯化方法 - Google Patents
一种重组人胰岛素的制备和纯化方法 Download PDFInfo
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- CN112300267A CN112300267A CN201910697368.0A CN201910697368A CN112300267A CN 112300267 A CN112300267 A CN 112300267A CN 201910697368 A CN201910697368 A CN 201910697368A CN 112300267 A CN112300267 A CN 112300267A
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- insulin
- recombinant human
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- protein
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
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- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
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- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
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Priority Applications (1)
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CN201910697368.0A CN112300267A (zh) | 2019-07-30 | 2019-07-30 | 一种重组人胰岛素的制备和纯化方法 |
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CN201910697368.0A CN112300267A (zh) | 2019-07-30 | 2019-07-30 | 一种重组人胰岛素的制备和纯化方法 |
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CN112300267A true CN112300267A (zh) | 2021-02-02 |
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CN201910697368.0A Pending CN112300267A (zh) | 2019-07-30 | 2019-07-30 | 一种重组人胰岛素的制备和纯化方法 |
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CN (1) | CN112300267A (zh) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101173006A (zh) * | 2006-10-30 | 2008-05-07 | 江苏万邦生化医药股份有限公司 | 一种重组人胰岛素的制备方法 |
CN101851249A (zh) * | 2010-06-18 | 2010-10-06 | 浙江华方药业有限责任公司 | 一种盐酸头孢卡品匹酯的制备方法 |
CN102504022A (zh) * | 2011-11-30 | 2012-06-20 | 苏州元基生物技术有限公司 | 含有保护赖氨酸的胰岛素原及使用其制备胰岛素的方法 |
CN103408497A (zh) * | 2013-07-17 | 2013-11-27 | 张家港威胜生物医药有限公司 | 一种关于l-肌肽的制备方法 |
CN107098845A (zh) * | 2017-07-06 | 2017-08-29 | 贵州大学 | 一种5‑氰基‑6‑硝基吲哚的制备工艺 |
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2019
- 2019-07-30 CN CN201910697368.0A patent/CN112300267A/zh active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101173006A (zh) * | 2006-10-30 | 2008-05-07 | 江苏万邦生化医药股份有限公司 | 一种重组人胰岛素的制备方法 |
CN101851249A (zh) * | 2010-06-18 | 2010-10-06 | 浙江华方药业有限责任公司 | 一种盐酸头孢卡品匹酯的制备方法 |
CN102504022A (zh) * | 2011-11-30 | 2012-06-20 | 苏州元基生物技术有限公司 | 含有保护赖氨酸的胰岛素原及使用其制备胰岛素的方法 |
CN103408497A (zh) * | 2013-07-17 | 2013-11-27 | 张家港威胜生物医药有限公司 | 一种关于l-肌肽的制备方法 |
CN107098845A (zh) * | 2017-07-06 | 2017-08-29 | 贵州大学 | 一种5‑氰基‑6‑硝基吲哚的制备工艺 |
Non-Patent Citations (3)
Title |
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CHUNSHENG LENG,等: "Application of recombinant enzymes in the production of human insulin", 《JOURNAL OF CHINESE PHARMACEUTICAL SCIENCES》 * |
翁樑,等: "重组人胰岛素的纯化及其性质的初步研究", 《生物科技通讯》 * |
郭新昆: "赖脯胰岛素生产工艺的研究", 《中国优秀硕士学位论文全文数据库》 * |
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Inventor after: Tang Yalian Inventor after: Wu Song Inventor after: Zhang Zhenshan Inventor after: Qian Junhui Inventor after: Li Kelang Inventor after: Liang Xinguang Inventor after: Yang Jieyun Inventor before: Zha Ruopeng Inventor before: Tang Yalian Inventor before: Wu Song Inventor before: Zhang Zhenshan Inventor before: Qian Junhui Inventor before: Li Kelang Inventor before: Liang Xinguang Inventor before: Yang Jieyun |
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