CN112292108A

CN112292108A - Skin care composition and kit thereof

Info

Publication number: CN112292108A
Application number: CN201880095132.3A
Authority: CN
Inventors: 于鲲
Original assignee: LOreal SA
Current assignee: LOreal SA
Priority date: 2018-06-28
Filing date: 2018-06-28
Publication date: 2021-01-29
Also published as: WO2020000290A1

Abstract

A composition kit for treating skin comprising composition I and composition II. The composition I comprises a water-insoluble substrate, wherein the calcium salt is homogeneously distributed in the substrate. Composition II comprises water, an alkali metal alginic acid compound, a preservative, a thickener, and optionally an organic solvent.

Description

Skin care composition and kit thereof

Technical Field

The present invention relates to kits in the cosmetic field, in particular to kits for caring for keratin materials, in particular the skin, such as the face, and in particular to kits useful for body film products, such as black body films. Furthermore, the invention relates to the use thereof, in particular as a body film product for caring for keratin materials, in particular the skin.

Background

The ultimate goal in the cosmetic field has always been to provide consumers with highly effective products with skin benefits such as hydration, moisturization, whitening, cleansing, and the like.

In all products for caring for keratin materials, in particular the skin, the body membranes are known to have a high penetration efficacy on keratin materials. Thus, a two-digit market growth of commercially available body film cosmetic products is seen.

There are generally four types of body films, namely paste type, peel type, gel type, and wet wipe type. Among them, paste-type and peel-type body films are mainly used for cleansing keratin materials, while gel-type and wet-wipe-type body films are more commonly used for caring skin. It is known that gel-type films have good adhesion to the skin and can provide a good refreshing feeling, but may be insufficient in delivering moisturizing or hydrating effects to the skin, while wet-wipe-type films are good in delivering moisturizing and hydrating effects but will recapture the effects if applied for an extended period of time. Furthermore, adhesion to skin may not be as good as gel-type films.

A new wet wipe body film product has been developed in which calcium alginate fibers are used to form a dry tissue, optionally together with another fiber conventionally used for body films, which is further immersed in an aqueous juice containing a soluble alginate (e.g., sodium alginate) to form a gel, see, e.g., CN 201420352058.8. However, in such films, calcium alginate can generally be used after being made into a fiber form.

There remains a need for new body films that combine two or more of the advantages exhibited by known body film types, but do not suffer from one or more of the problems associated therewith.

Summary of The Invention

It is an object of the present invention to provide a composition I useful for cosmetic products for caring for the skin, in particular the face, so as to bring about a good balance between gelling and homogeneity of the gel formed.

It is another object of the present invention to provide a kit comprising a plurality of compositions, said kit comprising composition I, which allows a user to apply composition I to a body film by fresh mixing.

It is a further object of the present invention to provide a package form for dispensing the kit of the present invention.

Accordingly, it is an aspect of the present invention to provide a composition I comprising a water-insoluble substrate, wherein the calcium salt is homogeneously distributed/dispersed in the substrate. Preferably, composition I is in the form of a dry body film, without any essences (stress), juices (juice) or any other impregnants.

Another aspect of the invention is to provide a kit comprising composition I as a dry body film wipe, and an aqueous composition II, said aqueous composition II comprising water; a preservative; a thickener; and optionally an organic solvent. Preferably, composition II is in the form of an aqueous sap.

Surprisingly, the present inventors have found that the use of calcium salts uniformly distributed/dispersed in dry body film towels can result in freshly mixed body films that can be easily manufactured, substantially maintaining the advantages of conventional gel-type body films and wet wipe-type body films, particularly in terms of gelling and uniformity of gel formed on the towel body film (tissue mask).

Other advantages of the invention will become more apparent upon reading the following description and examples.

Detailed description of the invention

Other than in the operating examples, or where otherwise indicated, all numbers expressing quantities of ingredients and/or reaction conditions are to be understood as being modified in all instances by the term "about", meaning within 10% of the number indicated (e.g., "about 10%" indicates 9% to 11%, and about "2%" indicates 1.8% to 2.2%).

The articles "a" and "an" as used herein mean one or more when applied to any feature in embodiments of the present invention described in the specification and claims. The use of "a" and "an" does not limit the meaning to a single feature unless such a limit is specifically stated. The article "the" preceding singular or plural nouns or noun phrases denotes a particular specified feature or particular specified features and may have a singular or plural connotation depending upon the context in which it is used. The adjective "any" means one, some, or all of any amount (not selected).

The term "comprising" (and grammatical variants thereof) as used herein is used in an inclusive sense of "having" or "including," and not in an exclusive sense of "consisting only of … …. However, the skilled person will undoubtedly appreciate that for embodiments that can be implemented in "comprising" form, the "form consisting essentially of … …" and "consisting of … …" are naturally modifications of this embodiment and are also within the scope of the invention.

All percentages and ratios are by weight unless otherwise indicated. All percentages are calculated based on the total weight of the composition, unless otherwise indicated. The levels of all components or compositions are in accordance with the active level of the component or composition and are exclusive of impurities, e.g., residual solvents or by-products, which may be present in commercially available sources.

By "fresh mixing" is meant that two or more compositions, each contained in separate chambers of the kit, are mixed together by the user at the instant he/she intends to apply the mixed composition.

Composition I

The composition I provided according to the present invention comprises a water-insoluble substrate in which the calcium salt is homogeneously distributed/dispersed.

For the purposes of the present invention, the term "water-insoluble" means that the substrate is insoluble in water and does not disintegrate upon immersion/immersion in water.

Generally, the substrate may be a woven or non-woven cloth/tissue made of fibers selected from natural fibers such as cotton, pulp, bamboo and cellulose fibers, semi-natural fibers such as viscose rayon, charcoal viscose, bamboo charcoal viscose, synthetic fibers such as polyester, polyethylene terephthalate, polyethylene, polypropylene fibers, or mixtures thereof. The fibres are preferably viscose, lyocell and more preferably viscose.

The substrate may be formed into a wide variety of shapes and forms, such as flat pads, thick pads, thin sheets of irregular thickness, depending on the desired use and characteristics of the kit. By way of example only, in the case of a body membrane, the substrate is typically designed to conform to an area of skin that requires topical application. To this end, the substrate is designed to correspond to the shape of the face, avoiding the eyes, nostrils and mouth area as needed, when applying the body membranes to the face. Non-limiting examples of substrates that can be used in the present invention are described in, for example, patent application WO 02/062132 or EP 2489286 a.

In particular, the water-insoluble substrate or cloth/tissue may comprise fibers in an amount of from 1 to 100 wt. -%, preferably from 5 to 100 wt. -%, especially from 10 to 99 wt. -%, for example from 50 to 99 wt. -%, or from 80 to 99 wt. -%, relative to the total weight of composition I.

Calcium salt

The composition I provided according to the present invention comprises calcium salts homogeneously distributed/dispersed in the substrate. The salt may be formed from calcium and an organic or inorganic acid.

The anion of the calcium salt may be a moiety derived from an inorganic acid. Useful salts derived from inorganic acids include, for example, calcium sulfate, calcium phosphate, calcium nitrate, calcium carbonate, calcium halides, such as calcium chloride, calcium bromide, calcium iodide, and the like. Calcium halides, in particular calcium chloride or calcium bromide, are preferred.

The anion of the calcium salt may be a moiety derived from an organic acid. Useful organic acids are preferably carboxylic acids. The carboxylic acid includes, for example, a linear or branched saturated or unsaturated carboxylic acid. The saturated carboxylic acids preferably have from 1 to 30, preferably from 3 to 18, or preferably from 5 to 12 carbon atoms. Useful carboxylic acids also include hydroxycarboxylic acids, including monohydroxycarboxylic acids and polyhydroxycarboxylic acids. Useful carboxylic acids further include amino acids. Examples of organic acids that can be used include, for example, pantothenic acid, ascorbic acid, and the like, with pantothenic acid being preferred.

The calcium salt is used in an amount sufficient to form a gel with the alginate on the substrate. Thus, calcium salts are generally available in amounts of about 0.1 to about 20 mmol Ca²⁺/m²Substrate, preferably about 0.3 toAbout 10 mmol/m²Or from about 0.4 to about 6 mmol/m²Or from about 0.5 to about 5 mmol/m²Or from about 0.6 to about 3 mmol/m²The amount of (c) is used.

Other Components

Composition I according to the present invention may comprise any component useful for body films, including but not limited to the components of composition II to be discussed subsequently, as long as the presence of one or more other components will maintain composition I in a dry form.

Method of forming composition I

The method of forming composition I is not particularly limited, as long as the calcium salt is capable of being uniformly distributed in the substrate in an amount sufficient to form a gel with the alginate on the substrate.

According to one embodiment, the calcium salt is prepared as an aqueous solution. Subsequently, the calcium salt is loaded onto a substrate (e.g., a body film towel) by immersing the substrate in the solution, infusing the solution into the substrate, spraying the solution onto the substrate, and the like.

According to another embodiment, the calcium salt is prepared as a suspension or paste, e.g., a water-soluble calcium salt is suspended in or mixed with an aqueous medium other than water to form a suspension or paste thereof. Subsequently, the suspension or paste is applied to the substrate, for example by coating, spraying or the like, so that the calcium salt is distributed uniformly in the substrate in an amount sufficient to form a gel with the alginate on the substrate.

According to another embodiment, the calcium salt is prepared as an aqueous dispersion, for example for water-insoluble calcium salts (a more preferred example is a calcium salt suspension or paste, since the water-soluble calcium salt is suspended in other aqueous media than water, and therefore it does not conflict with the previous invention, and the water-soluble calcium reacts more readily with the sodium alginate in composition 2). Subsequently, the dispersion is applied to the substrate, for example by coating, spraying or the like, so that the calcium salt is distributed uniformly in the substrate in an amount sufficient to form a gel with the alginate on the substrate.

For the case of applying the calcium salt using an aqueous solution, aqueous dispersion, suspension or paste, the wet substrate loaded with an aqueous salt (aquous salt) is subsequently dried. The method of drying the tissue is not particularly limited. For industrial applications, the wet substrate is dried in an economically efficient manner.

According to yet another embodiment, the calcium salt in solid form (e.g. as a water-insoluble salt) is comminuted into a powder or particles, e.g. by grinding, milling or the like. Subsequently, the powder or particles are applied uniformly to the substrate. The diameter of the powder or particles is not particularly limited as long as the calcium salt is uniformly distributed in the substrate in an amount sufficient to form a gel with the alginate on the substrate.

Aqueous composition II

According to the present invention, an aqueous composition II is provided for use as aqueous composition II in a kit comprising composition I as a dry body film towel.

The aqueous composition II comprises water.

The water used may be sterile demineralized water and/or floral water (floral water), such as rose, cornflower, chamomile or lyme (lime blossom) water, and/or natural or mineral water, for example: vittel water, Vichy basin water, Urage water, Roche Posay water, Bourboule water, Enghien-les-Bains water, Saint Gervais-les-Bains water, N é -les-Bains water, Allevar-les-Bains water, Digne water, Maizi res water, Neyrac-les-Bains water, Lons-le-Sauneer water, Eaux Bonnes water, Rochefort water, Saint Christu water, Fumades water, Tercis-les-Bains water, and Avene water. The aqueous phase may also comprise reconstituted spring water, i.e. water containing trace elements such as zinc, copper, magnesium, etc. characteristic of reconstituted spring water.

According to a preferred embodiment, the water is present in an amount of from 20% to 99.9% by weight, preferably from 50% to 99.9% by weight, preferably from 70% to 99.9% by weight, preferably from 80% to 99.7% by weight, or preferably from 88% to 99.65% by weight, relative to the total weight of composition II.

Alkali metal alginic acid compound

The aqueous composition II may further comprise an alkali metal alginic acid compound.

The term "alkali metal alginic acid compound" especially refers to alkali metal alginates (alginates) or alkali metal salts of alginic acid derivatives. The alkali metal alginic acid compound is water soluble.

Alginic acid (a natural substance obtained from brown algae or from certain bacteria) is composed of two uronic acids linked together via a 1, 4-glycosidic bond: polyuronic acid consisting of beta-D-mannuronic acid (M) and alpha-L-glucuronic acid (G).

Alginic acid can form water soluble salts (alginates) with alkali metals such as sodium, potassium or lithium. These alginates are water soluble in aqueous media at pH 4, but dissociate to alginic acid at pH below 4.

Methods for recovering these water-soluble salts, particularly sodium alginate, from natural sources are well known and described, for example, in Green, U.S. patent No. 2,036,934 and Le Gloahec, U.S. patent No. 2,128,551.

Alginic acid or alginates may be chemically modified, especially with urea or urethane groups, or by hydrolysis, oxidation, esterification, etherification, sulphation, phosphorylation, amination, amidation or alkylation reactions, or by several of these modifications, to form alginic acid derivatives, including salts.

These derivatives may be anionic, cationic, amphoteric or nonionic and are capable of forming water soluble salts with alkali metals, such as sodium, potassium or lithium, to form the alkali metal salts of alginic acid derivatives.

More specifically, alginates can be reacted with alkylene oxides, such as ethylene oxide or propylene oxide, to form polyglycol alginates. The polyglycol segment is bonded to the alginate via one or more carboxyl groups. Typically, alginates react with propylene oxide to form polypropylene glycol alginate (PPG alginate), and ethylene oxide to form polyethylene glycol alginate (PEG alginate). The preparation of polyglycol alginates is disclosed in Strong, U.S. patent No. 3,948,881, Pettitt, U.S. patent No. 3,772,266, and Steiner, U.S. patent No. 2,426,125.

Preferably, the polyglycol alginate has a degree of esterification of from about 40% to about 95%, more preferably from about 70% to 95%.

Suitable alginates have a weight average molecular weight of about 20,000 daltons to about 500,000 daltons. As in Martinsen et al, "comprehensive of Differencen Methods for Determination of Molecular Weights and Molecular Weight Distribution of Alginates" (Carbohydr. Polymer., 15, 171-Bukurad 193, 1991), the intrinsic viscosity is first determined, followed by calculation of the Weight average Molecular Weight using the Mark-Houwink Sakurad equation.

The weight average molecular weights indicated above are also valid for the alkali metal salts of alginic acid derivatives.

A list of various commercially available alginates, their properties, and their source can be found in Shapiro, U.S. patent No. 6,334,968, table 1, column 16, line 49 to column 17, line 18, which is incorporated herein by reference.

According to one embodiment of the invention, the alkali metal alginic acid compound may be selected from sodium alginate and potassium alginate, preferably sodium alginate. It is known in the art that sodium alginate can be commonly and directly referred to as algin. Thus, in the present specification, the term "algin" means sodium alginate.

The alkali metal alginic acid compound suitable for use in the present invention may be represented, for example, by the following: cargill Products Inc. named Kelcosol, Satialgine, Cecalgum or Algogel, FMC Biopolymer Inc. named Protanal, Danisco Inc. named Grindsted Alginate, Kimica Inc. named Kimica Algin and ISP sold under the names Manucol and Manugel.

The alkali metal alginic acid compound can generally be used in an amount sufficient to form a gel with the calcium salt on the substrate after application of the aqueous composition II to the composition I. For example, the alkali metal alginic acid compound may be used in an amount of about 0.05% to about 1%, preferably about 0.15% to about 0.7%, or about 0.2% to about 0.5%, or about 0.2% to about 0.4%, relative to the total amount of composition II.

Organic solvent

The aqueous composition II may also comprise a water-miscible organic solvent (at room temperature: 25 ℃), for example a monohydric alcohol containing from 2 to 6 carbon atoms, such as ethanol or isopropanol; polyols comprising at least two free hydroxyl groups, in particular having from 2 to 20 carbon atoms, preferably from 2 to 10 carbon atoms, and preferably from 2 to 6 carbon atoms, such as glycerol, ethylene glycol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, dipropylene glycol or diethylene glycol, for example glycerol.

The polyol may be present in the aqueous phase according to the invention in an amount of less than or equal to 30% by weight, preferably from 0.1% to 20% by weight, or preferably from 3% to 15% by weight, or from 5% to 12% by weight, relative to the total weight of the aqueous composition II.

Gelling agent

The composition according to the invention comprises one or more hydrophilic gelling agents.

For the purposes of the present patent application, the term "hydrophilic gelling agent" refers to a compound capable of gelling the aqueous phase of the composition II according to the invention. More particularly, these hydrophilic gelling agents function to structure the aqueous phase of the intermediate composition, thereby maintaining the structured composition once the water is removed from the composition. Such gelling agents may be introduced with the aqueous phase of the intermediate composition or with the pulverulent phase. The gelling agent is advantageously soluble in the aqueous phase of the intermediate composition.

The gelling agent that can be used according to the invention may be particularly characterized by its ability to form a gel in water beyond a certain concentration C, said gel being characterized by a flow threshold τ at least equal to 10 Pa_cOscillatory rheology of (μ = 1 Hz). This concentration C may vary to a large extent depending on the nature of the gelled polymer under consideration.

The gelling agent may be present in the composition II in an amount sufficient to adjust the stiffness modulus G (1 Hz, 25 ℃) of the composition to a value greater than or equal to 10000 Pa and in particular from 10000 Pa to 100000 Pa.

Methods for measuring these parameters of composition II are described, for example, in the paragraph entitled "rheological characterization" of patent application EP 1534218.

It is to be understood that alkali metal salts, alkaline earth metal salts or transition metal salts, such as zinc stearate, zinc myristate or magnesium stearate, are not considered hydrophilic gelling agents within the meaning of the present invention. In particular, such compounds act firstly and mainly as fillers and in particular as agents for compacting pulverulent phases.

Thickening filler

The thickening filler may act as an aqueous phase gelling agent. Such fillers preferably comprise clays and/or hollow mineral or organic microspheres capable of swelling in water.

The clay present in the composition according to the invention is a clay capable of swelling in water; the clay swells in water and forms a colloidal dispersion upon hydration.

Clay is a product known per se, which is described, for example, in the publication Mineralogie des argiles [ mineral of clays ], S.Caillere, S.H.nin, M.Rautureau, 2 nd edition 1982, Masson.

Clays are silicates containing cations advantageously selected from calcium, magnesium, aluminium, sodium, potassium and lithium cations and mixtures thereof.

Examples of such products which may be mentioned include clays of the smectite series, such as montmorillonite, hectorite, bentonite, beidellite and saponite (saponites), and clays of the vermiculite, stevensite and chlorite series.

These clays may be of natural or synthetic origin. Preferably, a cosmetically compatible and dermatologically acceptable clay is used.

According to a particularly preferred embodiment of the invention, the clay used, which is capable of swelling in water, is chosen from, for example, montmorillonite, hectorite, bentonite, beidellite and saponite, and more particularly hectorite and bentonite.

As clays which can swell in water that can be used according to the invention, mention may be made of synthetic hectorites (also known as laponites), such as the products sold under the name Laponite XLG, Laponite RD and Laponite RDs by the Laporte company (these products are sodium magnesium silicates and in particular sodium lithium magnesium silicates); bentonite, such as the product sold under the name Bentone HC by the company Rheox; magnesium aluminum silicates, especially hydrated, such as the product sold under the name Veegum Ultra by the Vanderbilt Company, or calcium silicates, and especially the product sold in synthetic form under the name Micro-cel C by the Company.

Preferably, when a thickening filler is used as hydrophilic gelling agent, such as clay, at least one different additional filler is provided in said pulverulent phase of the composition.

The clay may be present in composition II in a content ranging from 0.5% to 5% by weight and better still from 1% to 3% by weight, relative to the total weight of the composition.

Thickening agent

More particularly, the gelling agent may be chosen from the following polymeric thickeners:

acrylic or methacrylic homo-or copolymers or salts and esters thereof, and in particular polyacrylic acids of the Synthalen K type, and salts of polyacrylic acids, in particular sodium salts (corresponding to the INCI name of the sodium acrylate copolymer), and more particularly crosslinked sodium polyacrylates (corresponding to the INCI name of the sodium acrylate copolymer (and) caprylic/capric triglyceride) sold by Allied Colloid company under the name Versicol F or Versicol K, Ciba-Geigy under the name of Ultrahold 8, and by the company Luvigel EM;

copolymers of acrylic acid and of acrylamide sold by the company Hercules under the name Reten in the form of the sodium salt of a copolymer of acrylic acid and of acrylamide, sodium polymethacrylate sold by the company Vanderbilt under the name Darvan number 7, and the sodium salt of a polyhydroxycarboxylic acid sold by the company Henkel under the name Hydagen F;

-polyacrylic acid/alkyl acrylate copolymers, preferably modified or unmodified carboxyvinyl polymers; the most particularly preferred copolymers according to the invention are acrylates/acrylic acid C₁₀-C₃₀Alkyl ester copolymers (INCI name: acrylate/acrylic acid C)_10-30Alkyl ester cross-linked polymers), such as those sold by the company Lubrizol under the trade names Pemulen TR1, Pemulen TR2, Carbopol 1382, and Carbopol EDT 2020, and even more preferably Pemulen TR-2;

AMPS (polyacrylamide-based aminomethylpropanesulfonic acid partially neutralized with ammonia and highly crosslinked) sold by Clariant;

AMPS/acrylamide copolymers, such as Sepigel or Simulgel, products sold by the SEPPIC company, in particular the copolymers of polyacrylamide (and) C13-14 isoparaffin (and) laureth-7, under the INCI name;

polyoxyethylated AMPS/alkyl methacrylate copolymers (crosslinked or not) of the Aristoflex HMS type, as sold by Clariant corporation;

-and mixtures thereof.

Other examples of polymeric thickeners that may be mentioned include:

-anionic, cationic, amphoteric or non-ionic chitin or chitosan polymers;

-a cellulose polymer other than alkyl cellulose selected from the group consisting of hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxymethyl cellulose, ethyl hydroxyethyl cellulose and carboxymethyl cellulose and quaternized cellulose derivatives;

vinyl polymers, such as polyvinylpyrrolidone, copolymers of methyl vinyl ether and malic anhydride, copolymers of vinyl acetate and crotonic acid, copolymers of vinylpyrrolidone and vinyl acetate; copolymers of vinylpyrrolidone and caprolactam; polyvinyl alcohol;

optionally modified polymers of natural origin, such as:

galactomannans and derivatives thereof, such as konjac gum, gellan gum, locust bean gum, fenugreek gum, karaya gum, tragacanth gum, acacia gum (gum arabic), acacia gum (acacia gum), guar gum, hydroxypropyl guar modified with sodium methyl carboxylate groups (Jaguar XC97-1, Rhodia), hydroxypropyl trimethylammonium guar chloride, and xanthan derivatives;

-alginate and carrageenan;

-glyceroaminoglycans, hyaluronic acid and derivatives thereof;

-a deoxyribonucleic acid;

mucopolysaccharides, such as hyaluronic acid and chondroitin sulfate and mixtures thereof.

According to a particularly preferred embodiment, the gelling agent is chosen from associative polymers.

For the purposes of the present invention, the term "associative polymer" means any amphiphilic polymer comprising in its structure at least one fatty chain and at least one hydrophilic moiety. The associative polymers according to the invention may be anionic, cationic, nonionic or amphoteric.

The hydrophilic gelling agent or agents may be present in the composition II according to the invention in a solids content of greater than or equal to 0.1% by weight relative to the total weight of the composition II. In particular, the hydrophilic gelling agent or agents may be present in the composition II according to the invention in a solids content ranging from 0.1% to 5% by weight and preferably from 0.1% to 3% by weight, relative to the total weight of the composition II.

Preservative

For use as a body film, the composition II according to the invention may comprise at least one preservative. Preservatives which can be used in accordance with the present invention may be any of those conventionally used in cosmetic products, particularly for body films.

For example, preservatives that may be used in accordance with the present invention include methylchloroisothiazolinone, imidazolidinyl urea, derivatives of hydantoin (e.g., dmdmdmh), parabens, phenoxyethanol, benzyl alcohol, chlorphenesin, benzoic acid and its salts (e.g., sodium benzoate), potassium sorbate, hydroxyacetophenone, amino acid based preservatives, sorbitan octanoate, glyceryl octanoate, and the like.

Preferably, the concentration of the preservative is 0.01-5%, preferably 0.01-3%, preferably 0.01-1%, or preferably 0.01-0.5% by weight of the composition II.

pH regulator

The composition II according to the invention has a (slightly) acidic to neutral pH. For example, composition II may have a pH of 3-7, or preferably 4-7.

According to a particular embodiment of the invention, the two-phase composition comprises at least one pH adjusting agent.

For the purposes of the present invention, the term "pH regulator" means any additive used to regulate the pH of the composition II to which it is added.

The one or more pH adjusting agents may be selected from, for example, citric acid, sodium hydroxide, amino alcohols (such as ethanolamine and triethanolamine), amino sugars, amino acids, and alkali metal salts thereof.

Active agent

According to one embodiment of the invention, composition II may comprise at least one active agent.

Among all the active agents that can be used in the present invention, mention may be made in particular of: alpha-or beta-hydroxy acids, such as lactic acid, glycolic acid, citric acid, 5-octanoylsalicylic acid, alpha-hydroxydecanoic acid, alpha-hydroxylauric acid (alpha-hydroxyauric), tartaric acid, glucuronic acid, galacturonic acid, acrylic acid, alpha-hydroxybutyric acid, alpha-hydroxyisobutyric acid, malic acid, mandelic acid, phosphoric acid, pyruvic acid, lactobionic acid and salicylic acid.

Anti-acne agents such as salicylic acid or benzoyl peroxide, octopirox (octopirox), dextro-and levorotatory sulphur-containing amino acids, their salts and their N-acetyl derivatives, such as N-acetylcysteine, or agents intended to prevent skin ageing and/or to improve its condition, such as the alpha-and beta-hydroxy acids mentioned above, retinoids such as retinoic acid, retinol and its esters, such as for example retinol propionate and retinol acetate, or retinol palmitate, niacinamide, allantoin, aloe vera extract, azelaic acid, bisabolol, phytic acid, collagen or agents stimulating collagen formation, vitamins such as vitamin C or its derivatives, such as ascorbyl glucoside, vitamin E or its derivatives, vitamin A or its derivatives, vitamin F or its derivatives, Dextro-and laevo-sulfur containing amino acids and derivatives thereof as mentioned above, elastin, N-acetyl D-glucosamine, luteolin or antioxidants, such as green tea or active fractions thereof, glycerol, laponite, caffeine, essential oils (essential oils), colorants, free radical scavengers, moisturizers, depigmenting agents (depigmenting agents), agents for improving skin tone, such as artificial tanning agents of the dihydroxyacetone or tyrosine ester type, sebum regulators (liposolutors), softeners, anti-wrinkle agents, keratolytic agents, refreshing agents (fresheners), deodorants, anesthetics, nutritional agents and mixtures thereof. Whitening agents (whitening agents) such as kojic acid, ascorbic acid phosphate, ascorbic acid glucoside, ascorbic acid and mixtures thereof may also be used.

In the case of body membranes, active agents for improving skin condition, such as moisturizers or agents that help improve the natural lipid barrier, such as ceramides, cholesterol sulfate and/or fatty acids and mixtures thereof, may also be used. Enzymes active on the skin, such as proteases, lipases, cerebrosidases and/or melaninases (melanases) and mixtures thereof, may also be used.

As further examples of active agents that may be suitable for use in the practice of the present invention, there are the following agents: drugs, peptides, proteins, detectable labels (detectable labels), contrast agents (contrast agents), analgesics, anesthetics, antimicrobials, anti-yeast agents, antifungals, antivirals, anti-dermatitides, antipruritics, antiemetics, vasoprotectants, antihalation agents, anti-irritants, anti-inflammatory agents, immunomodulators, anti-hyperkeratotic agents (anti-hyperkeratotic agents), dry skin treatments, antiperspirants, anti-psoriatic agents (anti-psoriatic agents), anti-dandruff agents, anti-aging agents, anti-asthmatic and bronchodilators, sunscreens, antihistamines, healing agents (healing agents), corticosteroids, tanning agents, and mixtures thereof.

The level of at least one active agent in composition II and/or in the second composition may be adjusted according to the intended purpose of the kit. For example, more than 100 wt.%, such as from 150 wt.% to 300 wt.%, of the at least one active agent may be present relative to the total weight of composition II without the at least one active agent.

Auxiliary agent

In a known manner, the compositions of the invention may contain adjuvants common in the field under consideration. Examples of adjuvants which may be mentioned include moisturizers such as protein hydrolysates, sodium hyaluronate, plant extracts, fragrances, fillers, bactericides, dyes and colorants, softeners, electrolytes and other adjuvants conventionally used in skin care, especially for body membranes, or mixtures thereof.

It will be apparent to those skilled in the art that the optional additional compound or compounds and/or the amount thereof will be and can be selected with care so that the envisaged addition does not or substantially does not adversely affect the advantages of the second composition according to the present invention.

Sleeve box

The present invention provides a kit comprising a composition I and a composition II according to the present invention as described above, wherein composition I is separate from composition II.

The water-insoluble substrate can be formed into a dry body film without any serum, sap, or any other impregnant. Thus, the kit according to the invention is a fresh mix film kit.

For kits to be used by a user, composition II according to the present invention is included in an amount sufficient to saturate composition I. Thus, composition II is used in the same amount as used for conventional wet wipe films relative to a sheet of the water-insoluble substrate of composition I, e.g., a dry body film sheet.

For example, composition II may be included in the kit in an amount of from 2 to 45 grams per kit, preferably from 10 to 40 grams per kit or from 20 to 30 grams per kit.

Packaging form

The present invention provides a package comprising a plurality of chambers for dispensing a kit according to the present invention, wherein each composition of the kit of the present invention is contained in separate chambers that are isolated from each other. The compositions may be mixed together by fresh mixing.

When the kit consists of two compositions, such as composition II according to the present invention and composition I described above, a two-compartment package 1 may be used. The chamber 2 of the package 1 is configured to contain an aqueous composition II, for example in the form of a serum 4. The chamber 3 is configured to contain an aqueous composition I, such as a dried bamboo charcoal tissue 5.

The chambers 2 and 3 are isolated from each other so that the essence 4 remains separated from the dried bamboo charcoal paper towel 5 before use. The barrier between the chambers 2 and 3 is equipped with a switch 6, such as a valve, a push switch with a spring, etc. Subsequently, when switch 6 is pressed, serum 4 enters chamber 3 through switch 6, thereby being freshly mixed with paper towel 5 immediately before application to the skin.

Method and use

The compositions II and I according to the invention can generally be prepared according to the general knowledge of a person skilled in the art. However, it is understood that the person skilled in the art may select the method of preparation thereof on the basis of his/her general knowledge, taking into account the properties of the ingredients used, such as their solubility in the vehicle (vehicle) and the application envisaged for the composition or kit.

According to one embodiment, the composition II according to the invention can be used in any cosmetic product subjected to vulcanization that needs to avoid bad smells but contains a chelating agent.

According to one embodiment, the kit according to the present invention may be used for treating the skin. This use may manifest itself as a method of caring for the skin, in particular the face or the neck, comprising the steps of admixing composition II and composition II of the kit in a fresh mix and subsequently applying the mixture thus obtained as a body film onto said skin.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The definitions of terms in the present specification will apply when they contradict the meanings commonly understood by those skilled in the art to which the present invention pertains.

Unless otherwise indicated, all numbers expressing quantities of ingredients and so forth used in the description and claims are to be understood as being modified by the term "about. Accordingly, unless indicated to the contrary, the numerical values and parameters set forth herein are approximations that may vary depending upon the desired purpose.

All percentages in the present invention are by weight unless otherwise indicated.

Notwithstanding that the numerical ranges and parameters setting forth the broad scope of the invention are approximations, the numerical values set forth in the specific examples are reported as precisely as possible. Any numerical value, however, inherently contains certain errors necessarily resulting from the standard deviation found in their respective measurements. The following examples are intended to illustrate the invention without limiting the scope of the results.

Examples

The following compositions were prepared.

Preparation of inventive and comparative compositions and body films

First, a composition I having the following formulation was prepared (unless otherwise stated, the amounts of the components are expressed in parts by weight):

table 1: composition I-body membranes

Paper towel: sontara8620 from Sontara Old Hickory, Inc

The procedure is as follows:

1. aqueous solutions of 0.1% and 1% calcium chloride and 0.0016%, 0.1% and 0.4% calcium pantothenate, respectively, were prepared.

2. The prepared solution was applied in a per tissue basis (-350 cm)²) 10 grams were sprayed onto Sontara8620 and then heat dried.

Next, composition II having the following formulation was prepared (unless otherwise stated, the amounts of the components are expressed in parts by weight):

table 2: composition II

Components	Juice 1 (P968132 41)	Juice 2 (P968132 42)	Juice 3 (P968132 43)	Juice 4 (P968132 44)	Juice 5 (P968132 45)	Juice 6 (P968132 46)	Juice 7 (P968132 47)
								Hydroxy benzene Ethanones	0.5	0.5	0.5	0.5	0.5	0.5	0.5
Hydroxyethyl group Cellulose, process for producing the same, and process for producing the same	0.1	0.1	0.1	0.1	0.1	0.1	0.1
								Phycocolloid	0.1	0.2	0.3	0.4	0.5	0.6	0.7
Water (W)	88.3	88.2	88.1	88	87.9	87.8	87.7
								Glycerol	6	6	6	6	6	6	6
Propylene glycol	5	5	5	5	5	5	5

The procedure is as follows: the components of composition II were mixed to produce body membrane juices with phycocolloids containing 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, and 0.7%, respectively.

Subsequently, a body membrane kit was obtained by combining each composition I with composition II:

table 3: obtained kit

The procedure is as follows: formulations 1 to 5 were immersed in juices 1 to 7, respectively.

Evaluation of inventive and comparative films

The inventive and comparative films were evaluated using the following protocol.

The scheme is as follows: the kits of examples 1.1 to 3.7 and comparative examples 4.1 to 5.7 were tested for gelling and homogeneity, respectively.

Method for assessing gelation: each resulting kit was scored for gelation by a panel of 6 experts.

Gel rating (1-5):

1: imperceptible (poor); 2: weak; 3: medium; 4: strong; 5: dispersed gel (good)

Method for assessing homogeneity: the uniformity of each kit was scored by a panel of 6 experts.

Homogeneity rating (1-5):

1: non-uniformity; 2: is barely uniform; 3: only when pressed hard; 4: acceptable; 5: is homogeneous

The average score is provided below:

table 5: gel and uniformity scores for kits

Ex.	Fraction of gel	Fraction of homogeneity
			Ex.1.1	1	5
Ex.1.2	2	5
			Ex.1.3	3	5
Ex.1.4	4	5
			Ex.1.5	4	5
Ex.1.6	5	1
			Ex.1.7	5	1
Ex.2.1	2	5
			Ex.2.2	3	5
Ex.2.3	4	5
			Ex.2.4	4	5
Ex.2.5	5	2
			Ex.2.6	5	1
Ex.2.7	5	1
			Ex.3.1	2	5
Ex.3.2	4	5
			Ex.3.3	4	5
Ex.3.4	4	3
			Ex.3.5	5	1
Ex.3.6	5	1
			Ex.3.7	5	1
C.E.4.1	1	5
			C.E.4.2	1	5
C.E.4.3	1	5
			C.E.4.4	1	5
C.E.4.5	1	5
			C.E.4.6	2	5
C.E.4.7	2	5
			C.E.5.1	5	1
C.E.5.2	5	1
			C.E.5.3	5	1
C.E.5.4	5	1
			C.E.5.5	5	1
C.E.5.6	5	1
			C.E.5.7	5	1

From the provided scores it was concluded that the kit according to the invention achieves a uniform distribution of the calcium salt in the tissue fibres, so that the final gel film has a substantially good homogeneity. On the other hand, the final gel film is substantially well gelled. That is, the kit according to the present invention achieves a good balance between gelling and homogeneity.

It was further found that the concentration of phycocolloid in the aqueous composition II also significantly affects the gelling and homogeneity, wherein concentrations of 0.2-0.5 wt.%, preferably 0.2-0.4 wt.%, result in a relatively good balance. Without being bound by any theory, it is believed that the concentration of algin and Ca²⁺The ratio of the concentrations of alginate anions significantly affects the rate of gelation, which in turn affects the balance between gelation and homogeneity.

The foregoing description illustrates and describes the present disclosure. Additionally, the disclosure shows and describes only the preferred embodiments of the disclosure, but as mentioned above, it is to be understood that it is capable of changes or modifications within the scope of the concept as expressed herein, commensurate with the above teachings and/or the skill or knowledge of the relevant art. The above description is further intended to explain the best mode known of practicing the disclosure and to enable others skilled in the art to utilize the disclosure in such, or other, embodiments and with the various modifications required by the particular applications or uses disclosed herein. Accordingly, the description is not intended to limit the disclosure to the form disclosed herein. It is also intended that the appended claims be construed to include alternative embodiments.

All publications, patents, and patent applications cited in this specification are herein incorporated by reference as if each individual publication, patent, or patent application were specifically and individually indicated to be incorporated by reference for all purposes. In the event of inconsistencies, the present disclosure controls.

Claims

1. Composition I comprising a water-insoluble substrate, wherein the calcium salt is homogeneously distributed in said substrate.

2. Composition I according to claim 1, wherein the substrate is made of fibres selected from natural fibres, such as cotton, pulp, bamboo and cellulose fibres, semi-natural fibres, such as viscose rayon fibres, charcoal viscose fibres, bamboo charcoal viscose fibres, synthetic fibres, such as polyester fibres, polyethylene terephthalate fibres, polyethylene fibres, polypropylene fibres, or mixtures thereof.

3. Composition I according to any one of the preceding claims, wherein the substrate is in the form of a body film towel.

4. Composition I according to any one of the preceding claims, wherein the calcium salt is formed from calcium and an organic or inorganic acid.

5. Composition I according to claim 4, wherein the inorganic acid comprises calcium sulphate, calcium phosphate, calcium nitrate, calcium carbonate and calcium halides, such as calcium chloride, calcium bromide and calcium iodide.

6. Composition I according to claim 4, wherein the organic acid comprises hydroxycarboxylic acids and amino acids, such as pantothenic acid and ascorbic acid.

7. Composition I according to any one of the preceding claims, wherein the calcium salt is Ca at about 0.1 to about 20 mmol²⁺/m²Base material, preferably from about 0.3 to about 10 mmol/m²Or from about 0.4 to about 6 mmol/m²Or from about 0.5 to about 5 mmol/m²Or from about 0.6 to about 3 mmol/m²The amount of (c) is used.

8. Composition I according to any one of the preceding claims, wherein the composition I is dry.

9. A kit comprising a composition I according to any one of claims 1 to 8 as a dry body film wipe, and an aqueous composition II comprising water; an alkali metal alginic acid compound; a preservative; a thickener; and optionally an organic solvent.

10. The kit according to claim 9, wherein the preservative is selected from the group consisting of methylchloroisothiazolinone, imidazolidinyl urea, derivatives of hydantoin such as dmdmdmh, parabens, phenoxyethanol, benzyl alcohol, chlorphenesin, benzoic acid and salts thereof such as sodium benzoate, potassium sorbate, hydroxyacetophenone, amino acid based preservatives, sorbitan octanoate, glyceryl octanoate.

11. The kit according to claim 9 or 10, comprising an organic solvent selected from monohydric alcohols containing from 2 to 6 carbon atoms, such as ethanol or isopropanol; and polyols comprising at least two free hydroxyl groups, in particular containing from 2 to 20 carbon atoms, preferably from 2 to 10 carbon atoms, and preferably from 2 to 6 carbon atoms.

12. The kit according to any one of claims 9 to 11, wherein the alkali metal alginic acid compound is used in an amount of about 0.05% to about 1%, preferably about 0.15% to about 0.7%, or about 0.2% to about 0.5%, or about 0.2% to about 0.4%, relative to the total amount of the composition II.

13. Use of a kit according to any of claims 9 to 12 for caring for the skin, in particular for the face or the neck.

14. Method for conditioning the skin comprising the step of freshly mixing composition I and composition II of a kit according to any one of claims 9 to 12 and subsequently applying them to a site where the mixture thus obtained is desired.