CN112185529A - Cold chain transportation effectiveness monitoring system and method - Google Patents
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Abstract
The invention discloses a cold chain transportation effectiveness monitoring system and method, which comprises a vaccine end to be tested, an intelligent terminal and an authentication center, wherein the vaccine end to be tested comprises a vaccine product, the vaccine product is provided with an identity authentication code of a vaccine and a temperature monitoring circuit, and the temperature monitoring circuit comprises a power supply module, a temperature threshold starting module, a temperature sensor, a logic circuit module, a clock module, an RFID chip and an RFID antenna. The invention relates to a hand-held terminal specially manufactured for a harsh cold chain storage environment, which can be operated in a cold storage and freezing environment, adopts a special anti-fog device technology and a waterproof infiltration sealing design of an internal structure of a machine body, avoids unstable factors caused by long-time operation in the cold storage, and simultaneously ensures continuous normal operation in a low-temperature environment as low as minus 20 ℃.
Description
Technical Field
The invention relates to the technical field of vaccine product monitoring, in particular to a cold chain transportation effectiveness monitoring system and method.
Background
The vaccine is a biological product which is prepared from various pathogenic microorganisms and is used for vaccination. Wherein the vaccine made with the bacteria or spirochetes is also called bacterin. Vaccines are divided into live and killed vaccines. The commonly used live vaccines include BCG vaccine, polio vaccine, measles vaccine, plague vaccine, etc. The commonly used killed vaccines include pertussis vaccine, typhoid vaccine, epidemic encephalitis vaccine, cholera vaccine and the like.
Vaccinations against chinese (vaccinines) fall into two categories.
The first class of vaccines are vaccines which are freely provided by the government to citizens and are to be vaccinated by the citizens according to the government regulations, and comprise vaccines determined by national immune planning, vaccines added by the national immune planning of the governments of provinces, autonomous regions and direct jurisdictions, and vaccines used for emergency vaccination or group preventive vaccination of the governments of people above county level or the organizations of the health competent departments thereof;
the second category of vaccines refers to other vaccines that are paid and voluntarily received by citizens.
For vaccines, the most important effect of temperature on the vaccine is its stability, ensuring that the efficiency of the vaccine is not reduced. In the production and manufacturing process of the vaccine, the national drug regulatory department has requirements on production and manufacturing standards of enterprises, and the vaccine is required to have certain stability, so that if the vaccine is separated from a refrigeration environment, the titer of the drug can still be ensured not to be obviously reduced, which is a main consideration for the refrigeration requirement of the vaccine.
During the process of storing and transporting the vaccine, the short time of leaving the refrigerated environment is sometimes difficult to avoid in the actual work, such as when the vaccine is transported to a cold storage or taken out from the refrigerated vehicle during the transportation process, and the vaccine is difficult to be prevented from being exposed to the room temperature during the vaccination process. The short exposure, from the information we know now and the knowledge of vaccine drugs, will not cause the vaccine to deteriorate, and the safety of the vaccine will not be affected. However, we should emphasize that the operation for a long time without refrigeration environment is not allowed, so our country has clear regulations in the vaccination regulations and the circulation management regulations of vaccines, and requires the vaccines to be stored and transported in the refrigeration environment, thus ensuring the effectiveness and safety of the vaccines to the maximum extent.
With the occurrence of Shandong vaccine events, there are significant problems with vaccine production, transportation, storage and use due to the lack of effective tools for vaccine monitoring.
Disclosure of Invention
The present invention is directed to a system and a method for monitoring cold chain transportation effectiveness, so as to solve the problems mentioned in the background art.
In order to achieve the purpose, the invention provides the following technical scheme:
a product effectiveness monitoring system is characterized by comprising a vaccine, food, medicines, an intelligent terminal and an authentication center, wherein a vaccine end to be tested comprises a vaccine product, the vaccine product is provided with an identity authentication code of the vaccine and a temperature monitoring circuit, the temperature monitoring circuit comprises a power module, a temperature threshold starting module, a temperature sensor, a logic circuit module, a clock module, an RFID chip and an RFID antenna, the temperature threshold starting module is responsible for monitoring the temperature around the vaccine product, once a temperature out-of-control state occurs, a power supply is started to supply power to the logic circuit, and the logic circuit collects the temperature around the vaccine product through the temperature sensor and stores the temperature in the RFID chip; the intelligent terminal comprises a camera, an NFC module and an internet module, the intelligent terminal collects identity information of an identity authentication code of a vaccine end to be verified through the camera, receives information in the RFID chip through the NFC module, integrates the two information and sends the two information to an authentication center through the internet for authentication;
a cold chain method comprises the following specific steps:
the first step is as follows: temperature control and heat preservation, constant temperature refrigeration house: the freezer that has the accuracy requirement to the temperature humidity of storage article, including constant temperature and humidity freezer, the gas conditioning freezer: the air conditioning can not only adjust the temperature and humidity in the warehouse, but also control the contents of oxygen and carbon dioxide in the warehouse, so that fruits and vegetables in the warehouse are in a dormant state, and the air conditioning is to reduce the oxygen concentration in the air from 21% to 3% -5%;
the second step is that: cold chain storage, which is generally used for fresh agricultural products, stores and preserves commodities and articles through a warehouse, and temporarily stores the commodities and articles due to the preposition of orders or the preposition of market forecast in the production and circulation processes of the commodities and the articles;
the third step: cold chain transmission, which is used for sorting and packaging fresh agricultural products by using required transmission mechanical equipment, appliances and the like;
the fourth step: when the cold chain is loaded and unloaded, the temperature of the goods is detected, and the unloading time of the cold storage and frozen goods is used for sealing the unloading vehicle and the unloading warehouse;
the fifth step: the information technology is a modern cold-chain logistics nervous system, and the cold-chain logistics informatization system comprises the following contents of information acquisition and tracking technology, information transmission and exchange technology and information processing technology;
and a sixth step: cold chain logistics comprise cold chain transportation, and the cold chain transportation mode comprises road transportation, waterway transportation, railway transportation and air transportation;
the seventh step: the cold chain quarantine inspection comprises the steps of carrying out transportation quantity, distance, pollution probability, conventional cleaning and disinfection sanitary treatment, and recording the time of cold chain materials in the RFID through real-time monitoring, wherein when the temperature exceeds or returns to a normal temperature interval, the voltage of a thermistor bridge is increased or reduced, so that the cpu works in a starting or stopping mode, and during the cpu works, time data are obtained from a clock and stored in the RFID.
As a further scheme of the invention: the RFID chip and the RFID antenna form a data reading system, and data is read when the logic circuit is in a dormant state.
As a still further scheme of the invention: the temperature interval is realized by adjusting the resistance value in the resistance bridge according to the temperature upper limit and the temperature lower limit specified by different products.
A method of monitoring a product effectiveness monitoring system, comprising the steps of:
A. the intelligent terminal collects identity information on an identity card code of a vaccine end to be verified through the camera, receives temperature information in the RFID chip of the vaccine end to be verified through the NFC module, integrates the identity information and the temperature information, and sends the integrated information to the authentication center through the Internet for authentication;
B. the authentication center is connected with a manufacturer through the Internet, obtains product information updated by the manufacturer at any time, and compares the product information with the acquired identity information and temperature information of the vaccine end to be verified for authentication;
C. if the authentication center authenticates correctly, the production information and the temperature monitoring information of the product are displayed to the intelligent terminal so as to ensure the effective use of the vaccine; and if the authentication is wrong, sending related display information to the intelligent terminal.
Compared with the prior art, the invention has the beneficial effects that:
1. the invention is an active monitoring system, the system is installed and matched after the vaccine is produced, the vaccine can be monitored in the whole process, and when the system is used, a user can obtain the factory production information of the vaccine and whether the temperature is out of control before the vaccine is used as long as the user scans and reads the content of the RFID chip of the vaccine through a mobile phone. And displaying relevant information to the client to remind the user whether the vaccine belongs to the normal use range.
2. The product effectiveness monitoring system can monitor the temperature of the production, transportation, storage and use conditions of the vaccine, ensure that the vaccine used by a user is an effective and normally usable vaccine, and can ensure the life safety of a vaccine vaccinee and the effectiveness of epidemic prevention after vaccine injection.
3. The invention relates to a hand-held terminal specially manufactured for a harsh cold chain storage environment, which can be operated in a cold storage and freezing environment, adopts a special anti-fog device technology and a waterproof infiltration sealing design of an internal structure of a machine body, avoids unstable factors caused by long-time operation in the cold storage, and simultaneously ensures continuous normal operation in a low-temperature environment as low as minus 20 ℃.
Drawings
Fig. 1 is a system configuration diagram of a cold chain transportation effectiveness monitoring system and method of the present invention.
Fig. 2 is a flow chart of a monitoring method of the cold chain transportation effectiveness monitoring system and method of the present invention.
Fig. 3 is a working schematic diagram of an RFID chip of the cold chain transportation effectiveness monitoring system and method of the present invention.
Fig. 4 is a working schematic diagram of an RFID chip of the cold chain transportation effectiveness monitoring system and method of the present invention.
Fig. 5 is a working flow chart of an RFID chip of the cold chain transportation effectiveness monitoring system and method of the present invention.
Fig. 6 is a flowchart of the intelligent terminal work of the cold chain transportation effectiveness monitoring system and method of the present invention.
Fig. 7 is a flowchart of the work flow of the authentication center of the cold chain transportation validity monitoring system and method of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
The embodiment consists of six parts: the method comprises the steps of a vaccine end to be verified, an intelligent terminal, an authentication center, a manufacturer, the Internet and a cold chain process.
Firstly, products to be tested: bar codes (or two-dimensional codes) and RFID chip internal codes (including process monitoring data) on products of official manufacturers to be verified.
In fig. 1, 1 is a bar code or a two-dimensional code of the product.
And 2, the temperature monitoring circuit comprises a power supply, a temperature threshold starting device, a temperature sensor, a logic circuit, a clock, an RFID chip and an RFID antenna, wherein the temperature threshold starting device is responsible for monitoring the ambient temperature, the power supply is started to supply power to the logic chip once the temperature out-of-control state occurs, and the logic chip collects the temperature and stores the temperature into the RFID chip. The RFID chip and the RFID antenna form a data reading system, and the data reading system can be used for reading when the logic circuit is in a dormant state.
II, intelligent terminal: the main equipment of human-computer interaction.
The intelligent terminal comprises three parts of hardware contents: the camera 3, the NFC module 4 and the internet 6 are connected (mobile data network or WIFI).
Develop APP and use on intelligent terminal, this APP can start camera 3 and treat bar code 1 (or two-dimensional code) of examining the product and scan, acquire product information, start NFC module 4 function and RFID chip communication, acquire the data information of storage on the RFID chip 2, integrate two information, send the authentication center to authenticate.
Receiving authentication center return information: the authentication is correct, and the production information and the temperature monitoring information of the product are displayed to the intelligent terminal user so as to ensure the effective use of the product; authentication errors, in two cases: 1. no production authentication information exists, and the product is a fake product; 2. and in the time period of out-of-control of the temperature, the out-of-control time, the temperature value and the like are displayed to the intelligent terminal user.
Thirdly, the authentication center: a center for verifying and verifying the bar code (or two-dimensional code) of the goods and the data in the RFID.
Software and a database are installed in the computer, and commodity information of manufacturers and information of products inquired and verified by users are recorded. The information is managed and a commodity authentication service is provided via the internet. And provides the manufacturer with the commodity condition inquiry.
Fourthly, manufacturers: the manufacturer of the product to be tested.
The authentication condition of the commodity can be inquired. When counterfeit or temperature runaway products occur, relevant information provided by the certification center for free is obtained. And further tracking the products.
Fifthly, internet: and the communication network connects the intelligent terminal, the authentication center and the manufacturer together.
A monitoring method of a product effectiveness monitoring system according to this embodiment is shown in fig. 2.
In fig. 1, the product end to be inspected comprises two parts: the bar code (or two-dimensional code) and temperature monitoring circuit of the product, wherein RFID adopts the RFID chip of 13.56MHz, this chip has standard communication function at the same time, there is newly developed storage logic, to keep the dynamic monitoring information, while the user inquires about the product, send the monitoring information that the authentication center keeps to the data. The principle is shown in fig. 3 and 4.
The function of the partial circuit is as follows: firstly, when the power is powered on for the first time, all circuits work, and the system enters a sleep state by related commands such as data sending set time and the like of the RFID. When the temperature is close to the critical value, the partial circuit is started to operate the power control circuit, so that the power supply supplies power to the system, the system collects the temperature, compares whether the temperature is out of range, records effective time and temperature value according to the clock when the temperature is out of range, and collects the temperature once every 5 minutes if the temperature is in the out-of-range state all the time and tries to enter the dormancy state. And thirdly, the information transmission between the two CPUs is completed by the EEPROM. And fourthly, the information of the RFID can be read at any time, and the circuit is not influenced even if the circuit enters a sleep state.
The chip work flow diagram is shown in fig. 5.
The intelligent terminal:
the intelligent terminal can be a computer, a tablet computer, a smart phone and the like, and is required to be provided with a camera, an RFID (or NFC), a display screen and an Internet connection. Acquiring anti-counterfeiting code information of the commodity through a camera and an RFID, applying for authentication (data comparison) to an authentication center through the Internet, displaying related product information when the authentication is correct, and updating coding information; when there is a problem, the related information is displayed. The process flow is shown in FIG. 6.
The authentication center:
the two-dimension code information and the dynamic coding information of the product are stored at the place where the two-dimension code can be authenticated. And when a client puts forward an authentication requirement, performing authenticity authentication on the product according to the stored information. The management of information and the completion of authentication are both performed automatically by the computer. The authentication process flow of the computer is shown in fig. 7.
The authentication center has the authentication function of the dynamic code of the product, and also has the functions of applying, authenticating, compiling and issuing the dynamic code, and the client can carry out the authentication through a network. When the database is managed, the information and the result of each authentication are also stored, so that the user can conveniently inquire. The authentication is accurately analyzed every time, and when a counterfeit product is found, the information can be timely sent to a client to enable the client to be informed.
A cold chain method comprises the following specific processes:
the first step is as follows: temperature control and heat preservation, constant temperature refrigeration house: the freezer that has the accuracy requirement to the temperature humidity of storage article, including constant temperature and humidity freezer, the gas conditioning freezer: the air conditioning system can adjust the temperature and humidity in the storage, can control the content of oxygen, carbon dioxide and other gases in the storage, enables fruits and vegetables in the storage to be in a dormant state, and the air conditioning is to reduce the oxygen concentration in the air from 21% to 3% -5%, namely, the fresh-keeping storage is based on a high-temperature storage, and is additionally provided with a set of air conditioning system to achieve the purpose of inhibiting the respiration state of the picked fruits and vegetables by utilizing the combined action of the temperature and the oxygen content control, wherein the constant value of the temperature is 8-30 ℃ below:
firstly, cooling and refreshing: seafood: 0-10 degrees;
secondly, freezing: pork: -30 degrees or less (0-20);
thirdly, refrigerating: red wine: 5-15;
fourthly, ensuring the temperature stability in the goods transferring warehouse;
the second step is that: cold chain storage, which is generally used for fresh agricultural products, stores and preserves commodities and articles through a warehouse, and temporarily stores the commodities and articles due to the preposition of orders or the preposition of market forecast in the production and circulation processes of the commodities and the articles;
the third step: cold chain transmission, namely sorting and packaging fresh agricultural products by classification by using required transmission mechanical equipment, appliances and the like at a certain temperature;
the fourth step: the method comprises the following steps that during loading and unloading of a cold chain, article temperature detection is carried out, unloading time of cold storage and frozen articles needs to be according to a specified requirement, a unloading vehicle and an unloading warehouse are subjected to sealing treatment, the temperature rise of the articles is controlled within an allowable range during unloading, and when unloading operation is interrupted, a door of a transport equipment compartment body needs to be closed immediately, and a refrigeration system is kept to operate normally;
the fifth step: the information technology is a modern cold-chain logistics nervous system, and by the support of a system information platform, strategic collaborative management of all resources of an enterprise is easy to realize, the cold-chain logistics cost is reduced, the market competition of cold-chain logistics enterprises is promoted, and the management level of the cold-chain logistics enterprises is improved;
and a sixth step: cold chain transportation is an important link of cold chain logistics, is high in cold chain transportation cost, and comprises a more complex mobile refrigeration technology and an insulation can manufacturing technology, and cold chain transportation management comprises more risks and uncertainties, and the cold chain transportation means transportation of keeping transported goods at a certain temperature all the time no matter links such as loading, unloading, carrying, transportation mode changing, packaging equipment changing and the like in the whole transportation process, and can be road transportation, waterway transportation, railway transportation, air transportation or comprehensive transportation mode consisting of multiple transportation modes;
the seventh step: the inspection of cold chain quarantine inspection needs to establish standard and ordered food quarantine inspection work, arrange transportation tools with large transportation amount, long distance and high pollution probability managed by special people, well perform conventional sanitary treatment such as cleaning, disinfection and the like, implement real-time monitoring and temperature recording work of cold chain logistics, ensure that the quality state of food meets the requirements in the transportation process and ensure the safety and sanitation of imported food.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (5)
1. A product effectiveness monitoring system is characterized by comprising a vaccine, food, medicines, an intelligent terminal and an authentication center, wherein a vaccine end to be tested comprises a vaccine product, the vaccine product is provided with an identity authentication code of the vaccine and a temperature monitoring circuit, the temperature monitoring circuit comprises a power module, a temperature threshold starting module, a temperature sensor, a logic circuit module, a clock module, an RFID chip and an RFID antenna, the temperature threshold starting module is responsible for monitoring the temperature around the vaccine product, once a temperature out-of-control state occurs, a power supply is started to supply power to the logic circuit, and the logic circuit collects the temperature around the vaccine product through the temperature sensor and stores the temperature in the RFID chip; the intelligent terminal comprises a camera, an NFC module and an internet module, the intelligent terminal collects identity information of an identity authentication code of a vaccine end to be verified through the camera, receives information in the RFID chip through the NFC module, integrates the two information and sends the information to an authentication center through the internet for authentication.
2. A cold chain method according to claim 1, comprising the specific steps of:
the first step is as follows: temperature control and heat preservation, constant temperature refrigeration house: the freezer that has the accuracy requirement to the temperature humidity of storage article, including constant temperature and humidity freezer, the gas conditioning freezer: the air conditioning can not only adjust the temperature and humidity in the warehouse, but also control the contents of oxygen and carbon dioxide in the warehouse, so that fruits and vegetables in the warehouse are in a dormant state, and the air conditioning is to reduce the oxygen concentration in the air from 21% to 3% -5%;
the second step is that: cold chain storage, which is generally used for fresh agricultural products, stores and preserves commodities and articles through a warehouse, and temporarily stores the commodities and articles due to the preposition of orders or the preposition of market forecast in the production and circulation processes of the commodities and the articles;
the third step: cold chain transmission, which is used for sorting and packaging fresh agricultural products by using required transmission mechanical equipment, appliances and the like;
the fourth step: when the cold chain is loaded and unloaded, the temperature of the goods is detected, and the unloading time of the cold storage and frozen goods is used for sealing the unloading vehicle and the unloading warehouse;
the fifth step: the information technology is a modern cold-chain logistics nervous system, and the cold-chain logistics informatization system comprises the following contents of information acquisition and tracking technology, information transmission and exchange technology and information processing technology;
and a sixth step: cold chain logistics comprise cold chain transportation, and the cold chain transportation mode comprises road transportation, waterway transportation, railway transportation and air transportation;
the seventh step: the cold chain quarantine inspection comprises the steps of carrying out transportation quantity, distance, pollution probability, conventional cleaning and disinfection sanitary treatment, and recording the time of cold chain materials in the RFID through real-time monitoring, wherein when the temperature exceeds or returns to a normal temperature interval, the voltage of a thermistor bridge is increased or reduced, so that the cpu works in a starting or stopping mode, and during the cpu works, time data are obtained from a clock and stored in the RFID.
3. The system and the method for monitoring the effectiveness of cold chain transportation according to claim 1, wherein the RFID chip and the RFID antenna form a data reading system, and data reading is performed when the logic circuit is in a dormant state.
4. The system and the method for monitoring the effectiveness of cold chain transportation according to claim 1, wherein the temperature interval is realized by adjusting the resistance value in the resistance bridge according to the upper temperature limit and the lower temperature limit specified by different products.
5. A method of monitoring the vaccine effectiveness monitoring system of claim 1, comprising the steps of:
A. the intelligent terminal collects identity information on an identity card code of a vaccine end to be verified through the camera, receives temperature information in the RFID chip of the vaccine end to be verified through the NFC module, integrates the identity information and the temperature information, and sends the integrated information to the authentication center through the Internet for authentication;
B. the authentication center is connected with a manufacturer through the Internet, obtains product information updated by the manufacturer at any time, and compares the product information with the acquired identity information and temperature information of the vaccine end to be verified for authentication;
C. if the authentication center authenticates correctly, the production information and the temperature monitoring information of the product are displayed to the intelligent terminal so as to ensure the effective use of the vaccine; and if the authentication is wrong, sending related display information to the intelligent terminal.
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Cited By (2)
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CN114338213A (en) * | 2021-12-31 | 2022-04-12 | 电子科技大学 | Temperature-assisted authentication system and authentication method thereof |
CN117635009A (en) * | 2024-01-25 | 2024-03-01 | 四川汇利实业有限公司 | Intelligent monitoring method, system, equipment and storage medium for cold chain transportation |
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