CN111840213A - 一种男性保健用抑菌养护凝胶及其制备方法 - Google Patents
一种男性保健用抑菌养护凝胶及其制备方法 Download PDFInfo
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- CN111840213A CN111840213A CN202010764423.6A CN202010764423A CN111840213A CN 111840213 A CN111840213 A CN 111840213A CN 202010764423 A CN202010764423 A CN 202010764423A CN 111840213 A CN111840213 A CN 111840213A
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- epimedium
- astragalus
- lysozyme
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Abstract
本发明公开了一种男性保健用抑菌养护凝胶及其制备方法，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物7‑11份，溶菌酵素6‑10份，萆薢6‑12份，东革阿里提取物7‑11份，人参提取物4‑8份，熟地黄提取物3‑7份，淫羊藿提取物4‑9份，巴戟天提取物3‑7份，肉苁蓉提取物3‑6份，沙苑子提取物6‑10份，当归提取物3‑8份，黄芪提取物5‑10份，育亨宾提取物4‑9份。本发明的抑菌养护凝胶对大肠杆菌、金黄色葡萄球菌、白色念珠菌具有抗菌作用，且抑菌养护凝胶全部采用纯天然植物萃取精华，结合科学调配及特殊生产工艺制作而成，具有抗菌清洁、修护调理等功效，适用于男性***感染及健康护理。
Description
技术领域
本发明涉及抑菌养护凝胶生产领域，尤其涉及一种男性保健用抑菌养护凝胶及其制备方法。
背景技术
***发痒是男性经常面临的问题，诱发***发痒的原因有很多，不注意个人卫生：或者大便没有解干净，便后***未擦拭干净，内裤没有勤换洗，导致细菌滋生，诱发***瘙痒，另外，寄生虫：如蛲虫、蛔虫、***滴虫、阴虱、疥疮等都是引起***瘙痒的重要因素。
通过药物可以治疗***瘙痒的病症，现有的治疗药物杀菌效果较差，且刺激性较大，患者易出现过敏症状，为此，我们提出了一种男性保健用抑菌养护凝胶及其制备方法。
发明内容
本发明的目的是提供一种男性保健用抑菌养护凝胶及其制备方法，解决了治疗药物杀菌效果较差，且刺激性较大，患者易出现过敏症状的问题。
为了达到上述目的，本发明是通过以下技术方案实现的：
本发明提供一种男性保健用抑菌养护凝胶及其制备方法，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物7-11份，溶菌酵素6-10份，萆薢6-12份，东革阿里提取物7-11份，人参提取物4-8份，熟地黄提取物3-7份，淫羊藿提取物4-9份，巴戟天提取物3-7份，肉苁蓉提取物3-6份，沙苑子提取物6-10份，当归提取物3-8份，黄芪提取物5-10份，育亨宾提取物4-9份。
优选的，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物10份，溶菌酵素8份，萆薢9份，东革阿里提取物9份，人参提取物7份，熟地黄提取物5份，淫羊藿提取物8份，巴戟天提取物7份，肉苁蓉提取物6份，沙苑子提取物9份，当归提取物5份，黄芪提取物9份，育亨宾提取物8份。
优选的，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物11份，溶菌酵素9份，萆薢10份，东革阿里提取物8份，人参提取物6份，熟地黄提取物7份，淫羊藿提取物7份，巴戟天提取物6份，肉苁蓉提取物5份，沙苑子提取物6份，当归提取物7份，黄芪提取物9份，育亨宾提取物9份。
优选的，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物10份，溶菌酵素8份，萆薢11份，东革阿里提取物10份，人参提取物8份，熟地黄提取物7份，淫羊藿提取物8份，巴戟天提取物6份，肉苁蓉提取物5份，沙苑子提取物8份，当归提取物6份，黄芪提取物6份，育亨宾提取物7份。
优选的，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物9份，溶菌酵素10份，萆薢11份，东革阿里提取物9份，人参提取物7份，熟地黄提取物6份，淫羊藿提取物8份，巴戟天提取物6份，肉苁蓉提取物6份，沙苑子提取物9份，当归提取物6份，黄芪提取物8份，育亨宾提取物5份。
优选的，所述金银花提取物为绿原酸，所述溶菌酵素纯品呈白色、微黄或黄色的结晶体或无定形粉末，无异味，微甜，易溶于水，所述溶菌酵素通过在蛋清中加入一定量的碘化物或碳酸盐等盐类，并调pH值至9.5-10.0，溶菌酶以结晶形式慢慢析出采用结晶纯化酶液经超滤处理后，用NaOH调整pH9.5，离心去除，上清液在缓缓搅拌下，加NaCl至5％，静置一周，得粗结晶，然后将结晶溶于pH4.6醋酸水中，分去不溶物后，进行重结晶制得，所述萆薢包括绵萆薢、粉萆薢，所述萆薢选自植物的干燥根茎，所述东革阿里提取物为从东革阿里叶、茎和根部中分离出来的联苯木质素、角鲨烯衍生物，所述熟地黄提取物为从熟地黄根中提取的有效物质。
优选的，所述黄芪提取物为豆科植物黄芪的干燥根提取物，所述黄芪提取主要含有皂苷、黄酮、多糖以及氨基酸等几类成分，所述育亨宾提取物为育亨宾的干燥树皮，所述育亨宾提取物白色结晶性粉末，味微苦。
优选的，所述当归提取物含藁本内酯、正丁烯酰内酯、阿魏酸、烟酸、蔗糖和多种氨基酸，以及倍半萜类化合物，所述肉苁蓉提取物为从寄生植物肉苁蓉中提取的物质，所述沙苑子提取物为沙苑子成熟种子，通过晒干粉碎制备。
优选的，所述巴戟天提取物为茜草科植物的干燥根除去须根，晒至六、七成干，轻轻捶扁，晒干制得，所述淫羊藿提取物为小檗科植物淫羊藿、箭叶淫羊藿、柔毛淫羊藿、巫山淫羊藿、或朝鲜淫羊藿的干燥地上部分晒干或阴干后的乙醇提取物。
本发明还提供一种男性保健用抑菌养护凝胶制作方法，具体包括以下步骤：
(1)按特定的组分及重量成分组成准备：树脂、滑石粉、碳酸钙、氧化铝粉末、氧化锌、碳酸甘油酯、湿润分散剂、蜡粉、颜料原材料；
(2)将滑石粉、碳酸钙、氧化铝粉末、氧化锌、碳酸甘油酯、蜡粉混合均匀，然后边加入湿润分散剂边进行研磨得到包覆粉体；
(3)将步骤(2)中得到的包覆粉体与颜料加入到树脂中，并搅拌均匀，在搅拌过程中再次加入湿润分散剂形成稳定乳浊液，即可得到涂料。
人参提取物可以增强人体表面细胞的活力。
淫羊藿提取物具有增强机体免疫功能的作用，能增强和保持正常的肾上腺皮质功能和免疫功能。
本发明的有益效果：本发明涂料添加的金银花提取物为绿原酸对大肠杆菌、金黄色葡萄球菌、白色念珠菌具有抗菌作用，且抑菌养护凝胶全部采用纯天然植物萃取精华，结合科学调配及特殊生产工艺制作而成，具有抗菌清洁、修护调理等功效，适用于男性***感染及健康护理等。
具体实施方式
下面结合实施例，对本发明的具体实施方式作进一步描述。以下实施例仅用于更加清楚地说明本发明的技术方案，而不能以此来限制本发明的保护范围。
实施例1
制作方法具体步骤如下：
(1)按照组分及重量成分组成准备：金银花提取物10份，溶菌酵素8份，萆薢9份，东革阿里提取物9份，人参提取物7份，熟地黄提取物5份，淫羊藿提取物8份，巴戟天提取物7份，肉苁蓉提取物6份，沙苑子提取物9份，当归提取物5份，黄芪提取物9份，育亨宾提取物8份；
(2)将上述原料分别研磨成粉末，将金银花提取物、溶菌酵素、萆薢、粉沙苑子提取物、黄芪提取物末混合均匀得到混合物A，然后将混合物A和去离子水按照比例1：2-4的比列混合得到混合物B；
(3)将混合物B在80-100℃下加热十分钟，然后过滤得到滤液A；
(4)将步骤(1)中得到的东革阿里提取物、人参提取物、熟地黄提取物、淫羊藿提取物、巴戟天提取物、粉末加入到滤液A中，并加入等体积的等离子水，在70-85℃下加热六分钟后加入肉苁蓉提取物、当归提取物、育亨宾提取物粉末，在60-70℃下加热五分钟，然后过滤得到滤液B，最后将滤液B真空压缩成糊状，制成药膏半成品。
(5)将药膏半成品冷却至室温，搅拌混合均匀得到抑菌养护凝胶产品。
实施例2
制作方法具体步骤如下：
(1)根据组分及重量成分组成准备：金银花提取物11份，溶菌酵素9份，萆薢10份，东革阿里提取物8份，人参提取物6份，熟地黄提取物7份，淫羊藿提取物7份，巴戟天提取物6份，肉苁蓉提取物5份，沙苑子提取物6份，当归提取物7份，黄芪提取物9份，育亨宾提取物9份；
(2)将上述原料分别研磨成粉末，将金银花提取物、溶菌酵素、萆薢、粉沙苑子提取物、黄芪提取物末混合均匀得到混合物A，然后将混合物A和去离子水按照比例1：2-4的比列混合得到混合物B；
(3)将混合物B在80-100℃下加热十分钟，然后过滤得到滤液A；
(4)将步骤(1)中得到的东革阿里提取物、人参提取物、熟地黄提取物、淫羊藿提取物、巴戟天提取物、粉末加入到滤液A中，并加入等体积的等离子水，在70-85℃下加热六分钟后加入肉苁蓉提取物、当归提取物、育亨宾提取物粉末，在60-70℃下加热五分钟，然后过滤得到滤液B，最后将滤液B真空压缩成糊状，制成药膏半成品。
(5)将药膏半成品冷却至室温，搅拌混合均匀得到抑菌养护凝胶产品。
实施例3
制作方法具体步骤如下：
(1)根据组分及重量成分组成准备：金银花提取物10份，溶菌酵素8份，萆薢11份，东革阿里提取物10份，人参提取物8份，熟地黄提取物7份，淫羊藿提取物8份，巴戟天提取物6份，肉苁蓉提取物5份，沙苑子提取物8份，当归提取物6份，黄芪提取物6份，育亨宾提取物7份；
(2)将上述原料分别研磨成粉末，将金银花提取物、溶菌酵素、萆薢、粉沙苑子提取物、黄芪提取物末混合均匀得到混合物A，然后将混合物A和去离子水按照比例1：2-4的比列混合得到混合物B；
(3)将混合物B在80-100℃下加热十分钟，然后过滤得到滤液A；
(4)将步骤(1)中得到的东革阿里提取物、人参提取物、熟地黄提取物、淫羊藿提取物、巴戟天提取物、粉末加入到滤液A中，并加入等体积的等离子水，在70-85℃下加热六分钟后加入肉苁蓉提取物、当归提取物、育亨宾提取物粉末，在60-70℃下加热五分钟，然后过滤得到滤液B，最后将滤液B真空压缩成糊状，制成药膏半成品。
(5)将药膏半成品冷却至室温，搅拌混合均匀得到抑菌养护凝胶产品。
实施例4
制作方法具体步骤如下：
(1)根据组分及重量成分组成准备：金银花提取物9份，溶菌酵素10份，萆薢11份，东革阿里提取物9份，人参提取物7份，熟地黄提取物6份，淫羊藿提取物8份，巴戟天提取物6份，肉苁蓉提取物6份，沙苑子提取物9份，当归提取物6份，黄芪提取物8份，育亨宾提取物5份；
(2)将上述原料分别研磨成粉末，将金银花提取物、溶菌酵素、萆薢、粉沙苑子提取物、黄芪提取物末混合均匀得到混合物A，然后将混合物A和去离子水按照比例1：2-4的比列混合得到混合物B；
(3)将混合物B在80-100℃下加热十分钟，然后过滤得到滤液A；
(4)将步骤(1)中得到的东革阿里提取物、人参提取物、熟地黄提取物、淫羊藿提取物、巴戟天提取物、粉末加入到滤液A中，并加入等体积的等离子水，在70-85℃下加热六分钟后加入肉苁蓉提取物、当归提取物、育亨宾提取物粉末，在60-70℃下加热五分钟，然后过滤得到滤液B，最后将滤液B真空压缩成糊状，制成药膏半成品。
(5)将药膏半成品冷却至室温，搅拌混合均匀得到抑菌养护凝胶产品。
以上所述，仅为本发明较佳的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，根据本发明的技术方案及其发明构思加以等同替换或改变，都应涵盖在本发明的保护范围之内。
Claims (10)
1.一种男性保健用抑菌养护凝胶，其特征在于，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物7-11份，溶菌酵素6-10份，萆薢6-12份，东革阿里提取物7-11份，人参提取物4-8份，熟地黄提取物3-7份，淫羊藿提取物4-9份，巴戟天提取物3-7份，肉苁蓉提取物3-6份，沙苑子提取物6-10份，当归提取物3-8份，黄芪提取物5-10份，育亨宾提取物4-9份。
2.根据权利要求1所述的一种男性保健用抑菌养护凝胶，其特征在于，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物10份，溶菌酵素8份，萆薢9份，东革阿里提取物9份，人参提取物7份，熟地黄提取物5份，淫羊藿提取物8份，巴戟天提取物7份，肉苁蓉提取物6份，沙苑子提取物9份，当归提取物5份，黄芪提取物9份，育亨宾提取物8份。
3.根据权利要求1所述的一种男性保健用抑菌养护凝胶，其特征在于，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物11份，溶菌酵素9份，萆薢10份，东革阿里提取物8份，人参提取物6份，熟地黄提取物7份，淫羊藿提取物7份，巴戟天提取物6份，肉苁蓉提取物5份，沙苑子提取物6份，当归提取物7份，黄芪提取物9份，育亨宾提取物9份。
4.根据权利要求1所述的一种男性保健用抑菌养护凝胶，其特征在于，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物10份，溶菌酵素8份，萆薢11份，东革阿里提取物10份，人参提取物8份，熟地黄提取物7份，淫羊藿提取物8份，巴戟天提取物6份，肉苁蓉提取物5份，沙苑子提取物8份，当归提取物6份，黄芪提取物6份，育亨宾提取物7份。
5.根据权利要求1所述的一种男性保健用抑菌养护凝胶，其特征在于，该抑菌养护凝胶的组分及重量成分组成包括：金银花提取物9份，溶菌酵素10份，萆薢11份，东革阿里提取物9份，人参提取物7份，熟地黄提取物6份，淫羊藿提取物8份，巴戟天提取物6份，肉苁蓉提取物6份，沙苑子提取物9份，当归提取物6份，黄芪提取物8份，育亨宾提取物5份。
6.根据权利要求1所述的一种男性保健用抑菌养护凝胶，其特征在于，所述金银花提取物为绿原酸，所述溶菌酵素纯品呈白色、微黄或黄色的结晶体或无定形粉末，无异味，微甜，易溶于水，所述溶菌酵素通过在蛋清中加入一定量的碘化物或碳酸盐等盐类，并调pH值至9.5—10.0，溶菌酶以结晶形式慢慢析出采用结晶纯化酶液经超滤处理后，用NaOH调整pH9.5，离心去除，上清液在缓缓搅拌下，加NaCl至5％，静置一周，得粗结晶，然后将结晶溶于pH 4.6醋酸水中，分去不溶物后，进行重结晶制得，所述萆薢包括绵萆薢、粉萆薢，所述萆薢选自植物的干燥根茎，所述东革阿里提取物为从东革阿里叶、茎和根部中分离出来的联苯木质素、角鲨烯衍生物，所述熟地黄提取物为从熟地黄根中提取的有效物质。
7.根据权利要求1所述的一种男性保健用抑菌养护凝胶，其特征在于，所述黄芪提取物为豆科植物黄芪的干燥根提取物，所述黄芪提取主要含有皂苷、黄酮、多糖以及氨基酸等几类成分，所述育亨宾提取物为育亨宾的干燥树皮，所述育亨宾提取物白色结晶性粉末，味微苦。
8.根据权利要求1所述的一种男性保健用抑菌养护凝胶，其特征在于，所述当归提取物含藁本内酯、正丁烯酰内酯、阿魏酸、烟酸、蔗糖和多种氨基酸，以及倍半萜类化合物，所述肉苁蓉提取物为从寄生植物肉苁蓉中提取的物质，所述沙苑子提取物为沙苑子成熟种子，通过晒干粉碎制备。
9.根据权利要求1所述的一种男性保健用抑菌养护凝胶，其特征在于，所述巴戟天提取物为茜草科植物的干燥根除去须根，晒至六、七成干，轻轻捶扁，晒干制得，所述淫羊藿提取物为小檗科植物淫羊藿、箭叶淫羊藿、柔毛淫羊藿、巫山淫羊藿、或朝鲜淫羊藿的干燥地上部分晒干或阴干后的乙醇提取物。
10.一种男性保健用抑菌养护凝胶的制作方法，其特征在于，采用权利要求1-9任一项所述的抑菌养护凝胶，具体包括以下步骤：
(1)根据组分及重量成分组成准备：金银花提取物，溶菌酵素，萆薢，东革阿里提取物，人参提取物，熟地黄提取物，淫羊藿提取物，巴戟天提取物，肉苁蓉提取物，沙苑子提取物，当归提取物，黄芪提取物，育亨宾提取物原材料；
(2)将上述原料分别研磨成粉末，将金银花提取物、溶菌酵素、萆薢、粉沙苑子提取物、黄芪提取物末混合均匀得到混合物A，然后将混合物A和去离子水按照比例1：2-4的比列混合得到混合物B；
(3)将混合物B在80-100℃下加热十分钟，然后过滤得到滤液A；
(4)将步骤(1)中得到的东革阿里提取物、人参提取物、熟地黄提取物、淫羊藿提取物、巴戟天提取物、粉末加入到滤液A中，并加入等体积的等离子水，在70-85℃下加热六分钟后加入肉苁蓉提取物、当归提取物、育亨宾提取物粉末，在60-70℃下加热五分钟，然后过滤得到滤液B，最后将滤液B真空压缩成糊状，制成药膏半成品。
(5)将药膏半成品冷却至室温，搅拌混合均匀得到抑菌养护凝胶产品。
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