CN111686061A - Composition with skin whitening and moisturizing effects and using method - Google Patents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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Abstract
The invention provides a composition with skin whitening and moisturizing effects, which consists of a bock greenbrier rhizome extract, rose hydrosol, chamomile hydrosol, sodium hyaluronate, butanediol, propylene glycol, sodium chloride, EDTA, dextran sodium sulfate and water. The formula of the invention has no toxic component and no skin irritation component, and is safe and effective. The invention has convenient use and quick response time, and can effectively improve the skin brightness and the skin water content.
Description
Technical Field
The invention relates to the field of cosmetic skin care, in particular to a composition with skin whitening and moisturizing effects and a using method thereof.
Background
With the improvement of living standard, people seek more diversified ways for beauty, and have higher attention on whitening skin care products developed by natural medicines. At present, the new generation of whitening skin care products pay more attention to compounding of various whitening active substances to generate a synergistic effect. The whitening components extracted from Chinese herbal medicines are gradually hot in the cosmetic industry due to the characteristics of mild skin, small irritation, stable drug property, high safety, lasting drug efficacy and the like.
In recent years, the diamond thorn is applied to the health food and traditional medicine industries, and the application of the diamond thorn in the aspect of cosmetic whitening is rarely reported.
At present, a composition which takes the chinaroot greenbrier rhizome as a raw material and has the effects of whitening and moisturizing the skin is not found.
Disclosure of Invention
The invention aims to provide a composition with skin whitening and moisturizing effects and a using method thereof.
In order to achieve the purpose, the invention provides a composition with skin whitening and moisturizing effects, which consists of a diamondback extract, rose hydrosol, chamomile hydrosol, sodium hyaluronate, butanediol, propylene glycol, sodium chloride, EDTA, dextran sodium sulfate and water.
Preferably, the composition consists of 15-25 wt% of the diamondback extract, 15-20 wt% of the rose hydrosol, 20-25 wt% of the chamomile hydrosol, 0.5-1.0 wt% of sodium hyaluronate, 1-4 wt% of butanediol, 1-2 wt% of propylene glycol, 1-3 wt% of sodium chloride, 1-5 wt% of EDTA, 1-3 wt% of dextran sodium sulfate and water which are supplemented to 100 wt%.
In one embodiment, the composition consists of diamondback extract 20 wt%, rose hydrosol 20 wt%, chamomile hydrosol 20 wt%, sodium hyaluronate 0.5 wt%, butanediol 4 wt%, propylene glycol 2 wt%, sodium chloride 3 wt%, EDTA5 wt%, dextran sodium sulfate 1 wt%, water supplemented to 100 wt%.
In one embodiment, the composition consists of 25 wt% of the extract of the diamondback, 15 wt% of the rose hydrosol, 20 wt% of the chamomile hydrosol, 1.0 wt% of the sodium hyaluronate, 2 wt% of the butanediol, 1 wt% of the propylene glycol, 1 wt% of the sodium chloride, 2 wt% of the EDTA, 3 wt% of the sodium dextran sulfate, and water supplemented to 100 wt%.
In one embodiment, the composition consists of 15 wt% of the extract of the diamondback, 20 wt% of the rose hydrosol, 25 wt% of the chamomile hydrosol, 0.5 wt% of the sodium hyaluronate, 1 wt% of the butanediol, 2 wt% of the propylene glycol, 2 wt% of the sodium chloride, 1 wt% of the EDTA, 2 wt% of the sodium dextran sulfate, and water supplemented to 100 wt%.
The invention also provides a composition with skin whitening and moisturizing effects, and the method comprises the following steps:
(1) crushing 10-30 parts of a bock greenbrier rhizome medicinal material, adding 8-15 times of 50-80% ethanol into the bock greenbrier rhizome medicinal material through a third sieve, performing ultrasonic extraction for 20-40 min at 300-400W, filtering, repeating the ultrasonic extraction for 1-2 times, combining filtrate, precipitating the filtrate overnight, and performing suction filtration; concentrating the filtrate under reduced pressure to obtain extract, drying, and pulverizing to obtain rhizoma Smilacis Bockii extract powder;
(2) adding water with the temperature of 40-60 ℃ according to the formula proportion into a preparation container, and starting stirring;
(3) adding sodium hyaluronate, stirring to fully dissolve the sodium hyaluronate, and stirring for 20-30 min;
(4) and (2) sequentially adding the diamondback extract obtained in the step (1), sodium chloride and propylene glycol, and continuously stirring for 10-20 min.
(5) And (3) sequentially adding butanediol, dextran sodium sulfate and EDTA, and continuously stirring for 10-20 min.
(6) Adding rose hydrosol and chamomile hydrosol, continuing stirring for 5-10 min, and stopping stirring to obtain the rose-camomile beverage.
In some of these embodiments, the method comprises the steps of:
(1) crushing 20 parts of the bock greenbrier rhizome medicinal material, sieving the crushed bock greenbrier rhizome medicinal material by a third sieve, adding 10 times of 75% ethanol, ultrasonically extracting for 30min at 400W, filtering, repeating for 1 time, combining filtrates, precipitating overnight, and performing suction filtration; concentrating the filtrate under reduced pressure to obtain extract, drying, and pulverizing to obtain rhizoma Smilacis Bockii extract powder;
(2) adding water with the temperature of 50 ℃ according to the formula proportion into a preparation container, and starting stirring;
(3) adding sodium hyaluronate, stirring to dissolve completely, and stirring for 20 min;
(4) sequentially adding the rhizoma Smilacis Bockii extract obtained in step (1), sodium chloride, and propylene glycol, and stirring for 10 min;
(5) sequentially adding butanediol, dextran sodium sulfate and EDTA, and stirring for 10 min;
(6) adding flos Rosae Rugosae hydrolat and flos Matricariae Chamomillae hydrolat certain ratio, stirring for 5min, and stopping stirring.
In some of these embodiments, the method comprises the steps of:
(1) pulverizing 20g rhizoma Smilacis Bockii, sieving with a third sieve, adding 8 times of 80% ethanol, ultrasonically extracting at 300W for 40min, filtering, repeating for 2 times, mixing filtrates, precipitating overnight, and vacuum filtering; concentrating the filtrate under reduced pressure to obtain extract, drying, and pulverizing to obtain rhizoma Smilacis Bockii extract powder;
(2) adding water with the temperature of 60 ℃ according to the formula proportion into a preparation container, and starting stirring;
(3) adding sodium hyaluronate, stirring to dissolve completely, and stirring for 30 min;
(4) sequentially adding the rhizoma Smilacis Bockii extract obtained in step (1), sodium chloride, and propylene glycol, and stirring for 20 min;
(5) sequentially adding butanediol, dextran sodium sulfate and EDTA, and stirring for 20 min;
(6) adding flos Rosae Rugosae hydrolat and flos Matricariae Chamomillae hydrolat certain ratio, stirring for 10min, and stopping stirring.
The invention also provides a use method of the composition with the skin whitening and moisturizing effects, wherein the composition is used every day for at least 2 weeks.
Preferably, the method is such that the composition is administered daily for at least 4 weeks.
The medicinal material of the invention, namely the chinaroot greenbrier rhizome, is dry rhizome of Smilax china.
Compared with the prior art, the invention has the following beneficial effects:
1. the formula of the invention has no toxic component and no skin irritation component, and is safe and effective.
2. The invention has convenient use and quick response time, and can effectively improve the skin brightness and the skin water content.
Detailed Description
Example 1Preparation of extract of rhizoma Smilacis Bockii
Crushing 20g of the bock greenbrier rhizome medicinal material, sieving the crushed bock greenbrier rhizome medicinal material by a third sieve, adding 10 times of 75% ethanol, ultrasonically extracting for 30min at 400W, filtering, repeating for 1 time, combining filtrates, precipitating overnight, and performing suction filtration; concentrating the filtrate under reduced pressure to obtain extract, drying, and pulverizing to obtain rhizoma Smilacis Bockii extract powder.
Example 2
(1) Adding water with the temperature of 50 ℃ according to the formula proportion into a preparation container, and starting stirring.
(2) Adding sodium hyaluronate, stirring to dissolve completely, and stirring for 20 min.
(3) The extract of Spanish Merrill obtained in example 1, sodium chloride, and propylene glycol were added in order, and stirring was continued for 10 min.
(4) Adding butanediol, dextran sodium sulfate, and EDTA sequentially, and stirring for 10 min.
(5) Adding flos Rosae Rugosae hydrolat and flos Matricariae Chamomillae hydrolat certain ratio, stirring for 5min, and stopping stirring.
Example 3
Pulverizing 20g rhizoma Smilacis Bockii, sieving with a third sieve, adding 8 times of 80% ethanol, ultrasonically extracting at 300W for 40min, filtering, repeating for 2 times, mixing filtrates, precipitating overnight, and vacuum filtering; concentrating the filtrate under reduced pressure to obtain extract, drying, and pulverizing to obtain rhizoma Smilacis Bockii extract powder.
(1) Adding water with the temperature of 60 ℃ according to the formula proportion into a preparation container, and starting stirring.
(2) Adding sodium hyaluronate, stirring to dissolve completely, and stirring for 30 min.
(3) The extract of Spanish Merrill, sodium chloride and propylene glycol obtained in example 3 were added in sequence and stirred for 20 min.
(4) Adding butanediol, dextran sodium sulfate, and EDTA sequentially, and stirring for 20 min.
(5) Adding flos Rosae Rugosae hydrolat and flos Matricariae Chamomillae hydrolat certain ratio, stirring for 10min, and stopping stirring.
Example 4
The amounts are shown in Table 1, and the preparation method is the same as that of example 2.
Comparative example
The amounts are shown in Table 1, and the preparation method is the same as that of example 2.
TABLE 1
Type of Material (wt%) | Example 2 | Example 3 | Example 4 | Comparative example |
Extract of Smilax chingii | 20 | 25 | 15 | / |
Rose pure dew | 20 | 15 | 20 | 30 |
Chamomile hydrolat | 20 | 20 | 25 | 30 |
Hyaluronic acid sodium salt | 0.5 | 1.0 | 0.5 | 0.5 |
Butanediol | 4 | 2 | 1 | 4 |
Propylene glycol | 2 | 1 | 2 | 2 |
Sodium chloride | 3 | 1 | 2 | 3 |
EDTA | 5 | 2 | 1 | 5 |
Dextran sodium sulfate | 1 | 3 | 2 | 1 |
Water (W) | To 100 of | To 100 of | To 100 of | To 100 of |
Whitening function test
First, experiment method
1. Method design
Volunteers were randomly selected and left and right faces were used as test areas, with the sample of example 2 (hereinafter, both referred to as experimental area) on one side and the sample of comparative example (hereinafter, both referred to as comparative area) on the other side. According to the test section, the test samples were used by the volunteers once a day in the morning and evening, and the application amount was according to the personal use habit (the volunteers were not allowed to use cosmetics similar to the test samples on their faces during the test period). The test period was 4 weeks total, during which the volunteers did not change the brand and usage habits of daily skin care products. Data acquisition, image acquisition, was performed on the test area before (week 0), after 1 week, 2 weeks and 4 weeks of product use. During the return visit, the dispensed test sample is reweighed. The fitness evaluation is performed by a dermatologist, the evaluation taking the form of clinical observations and interviews of volunteers, and the evaluation parameters include: redness, desquamation, itching, stinging, burning sensation, and others. Data and image acquisition were tested for the following indicators, respectively: skin whiteness L value, ITA DEG value skin melanin content MI value, skin moisture content MMV value.
2. Screening criteria
Selecting conditions are as follows: (1) volunteers who meet all the conditions listed below will be enrolled in the test for values of skin whiteness L and lightness ITA ° and skin melanin content MI. The number of cases is more than or equal to 25; age 18-55 years; sex randomization; the content of melanin in the skin on the inner side of the crank arm is 160-250; the whiteness L value of the skin on the inner side of the crank arm is between 55 and 65; in the last 1 month, no other product test is performed; those without severe systemic disease, immunodeficiency or autoimmune disease; those with inactive allergic disease; the past has no history of allergy to skin care cosmetics; in the last month, hormone drugs and immunosuppressants have not been used systemically; those who did not participate in other clinical trials; the person who voluntarily participates and can finish the specified contents according to the test requirements. (2) Volunteers meeting all of the following conditions will be enrolled in the test skin moisture content MMV values. Normal subjects of 20-65 years old have random gender and the number of the subjects is more than or equal to 20; those without severe systemic disease, immunodeficiency or autoimmune disease; those with inactive allergic disease; the past has no history of allergy to skin care cosmetics; in the last month, hormone drugs and immunosuppressants have not been used systemically; those who did not participate in other clinical trials; the person who voluntarily participates and can finish the specified contents according to the test requirements.
Exclusion criteria: pregnant or lactating women; outdoor work is the main, and sun exposure cannot be avoided; during the trial period, the hormone and immune preparation medicines are applied to the whole body; those who apply anti-inflammatory drugs during the trial period; the subject is not used as intended or the data is not complete.
3. Other requirements
The test sites did not use a cosmetic similar to the test samples for at least one week of the elution period, i.e., within one week prior to the test. Skin moisture content test sites were cheek (midline of eye and alar junction) and outside canthus. The other index testing part is the cheek (the junction of the midline of the eye and the nasal alar part)
4. Data processing
When the normal distribution is satisfied, the change of the data before and after the use of the sample and the difference between the test area and the matrix area are analyzed by using the t-test method. When the non-normal distribution is met, a rank sum test is applied.
Second, instrument and equipment
1. Instrument for measuring the position of a moving object
Skin color difference test probes and multifunctional skin test systems CL400 and MPA9 (CK company, germany); face image analysis system VISIA-CR (Canfield corporation, usa); skin black and red pigment tester MX18 (german CK company); skin moisture content tester CM825 (CK, germany).
2. Sample (I)
Example 2 comparative example
Third, experimental results
1. Skin whiteness
Table 2 results of skin whiteness before and after use (n ═ 35)
As can be seen from table 2, the skin whiteness L values of the subjects using the example 2 group showed a tendency to increase during the test period, and the data of the example 2 group was higher than the comparative group at both weeks 2 and 4, wherein the data of the example 2 group was significantly higher than the comparative group at week 4.
2. Skin brightness
Table 3 results of skin brightness before and after use (n ═ 35)
As can be seen from table 3, the skin brightness of the subjects showed a tendency to increase after using the example 2 group, and the example 2 group data was higher than the comparative group at both weeks 2 and 4 during the test period, wherein the example 2 group data was significantly higher than the comparative group at week 4.
3. Melanin content of skin
Table 4 results of skin melanin content before and after use (n ═ 35)
As can be seen from table 4, the skin melanin content of the subjects tended to decrease after using the example 2 group, and the example 2 group data was lower than the comparative group at both weeks 2 and 4 during the test period, wherein the example 2 group data was significantly lower than the comparative group at week 4.
4. Moisture content of skin
Table 5 skin moisture content MMV results before and after use (n ═ 35)
As can be seen from table 5, the skin moisture content of the subjects showed a tendency to increase after using the example 2 group, and the example 2 group data was higher than the comparative group at both weeks 2 and 4 during the test period, wherein the example 2 group data was significantly higher than the comparative group at week 4.
The foregoing descriptions of specific exemplary embodiments of the present invention have been presented for purposes of illustration and description. It is not intended to limit the invention to the precise form disclosed, and obviously many modifications and variations are possible in light of the above teaching. The exemplary embodiments were chosen and described in order to explain certain principles of the invention and its practical application to enable one skilled in the art to make and use various exemplary embodiments of the invention and various alternatives and modifications as are suited to the particular use contemplated. It is intended that the scope of the invention be defined by the claims and their equivalents.
Claims (10)
1. The composition with the skin whitening and moisturizing effects is characterized by comprising a bock greenbrier rhizome extract, rose hydrosol, chamomile hydrosol, sodium hyaluronate, butanediol, propylene glycol, sodium chloride, EDTA, dextran sodium sulfate and water.
2. The composition of claim 1, wherein the composition comprises 15-25 wt% of the extract of the adamantine thorn, 15-20 wt% of the rose hydrosol, 20-25 wt% of the chamomile hydrosol, 0.5-1.0 wt% of the sodium hyaluronate, 1-4 wt% of the butanediol, 1-2 wt% of the propylene glycol, 1-3 wt% of the sodium chloride, 1-5 wt% of the EDTA, 1-3 wt% of the sodium dextran sulfate, and water supplemented to 100 wt%.
3. The composition of claim 2, wherein the composition consists of 20 wt% of the extract of the plant adamantine, 20 wt% of the rose hydrosol, 20 wt% of the chamomile hydrosol, 0.5 wt% of the sodium hyaluronate, 4 wt% of the butanediol, 2 wt% of the propylene glycol, 3 wt% of the sodium chloride, 5 wt% of the EDTA, 1 wt% of the sodium dextran sulfate, and water up to 100 wt%.
4. The composition of claim 2, wherein the composition consists of 25 wt% of the extract of the plant adamantine, 15 wt% of the rose hydrosol, 20 wt% of the chamomile hydrosol, 1.0 wt% of the sodium hyaluronate, 2 wt% of the butanediol, 1 wt% of the propylene glycol, 1 wt% of the sodium chloride, 2 wt% of the EDTA, 3 wt% of the sodium dextran sulfate, and water up to 100 wt%.
5. The composition according to claim 2, wherein the composition consists of 15 wt% of the extract of the plant adamantine, 20 wt% of the rose hydrosol, 25 wt% of the chamomile hydrosol, 0.5 wt% of the sodium hyaluronate, 1 wt% of the butanediol, 2 wt% of the propylene glycol, 2 wt% of the sodium chloride, 1 wt% of the EDTA, 2 wt% of the sodium dextran sulphate and water up to 100 wt%.
6. A method for preparing the composition with skin whitening and moisturizing effects as claimed in any one of claims 1 to 5, wherein the method comprises the following steps:
(1) crushing 10-30 parts of a bock greenbrier rhizome medicinal material, adding 8-15 times of 50-80% ethanol into the bock greenbrier rhizome medicinal material through a third sieve, performing ultrasonic extraction for 20-40 min at 300-400W, filtering, repeating the ultrasonic extraction for 1-2 times, combining filtrate, precipitating the filtrate overnight, and performing suction filtration; concentrating the filtrate under reduced pressure to obtain extract, drying, and pulverizing to obtain rhizoma Smilacis Bockii extract powder;
(2) adding water with the temperature of 40-60 ℃ according to the formula proportion into a preparation container, and starting stirring;
(3) adding sodium hyaluronate, stirring to fully dissolve the sodium hyaluronate, and stirring for 20-30 min;
(4) sequentially adding the diamond-like carbon extract obtained in the step (1), sodium chloride and propylene glycol, and continuously stirring for 10-20 min;
(5) sequentially adding butanediol, dextran sodium sulfate and EDTA, and continuously stirring for 10-20 min;
(6) adding rose hydrosol and chamomile hydrosol, continuing stirring for 5-10 min, and stopping stirring to obtain the rose-camomile beverage.
7. The method according to claim 6, characterized in that it comprises the steps of:
(1) crushing 20 parts of the bock greenbrier rhizome medicinal material, sieving the crushed bock greenbrier rhizome medicinal material by a third sieve, adding 10 times of 75% ethanol, ultrasonically extracting for 30min at 400W, filtering, repeating for 1 time, combining filtrates, precipitating overnight, and performing suction filtration; concentrating the filtrate under reduced pressure to obtain extract, drying, and pulverizing to obtain rhizoma Smilacis Bockii extract powder;
(2) adding water with the temperature of 50 ℃ according to the formula proportion into a preparation container, and starting stirring;
(3) adding sodium hyaluronate, stirring to dissolve completely, and stirring for 20 min;
(4) sequentially adding the rhizoma Smilacis Bockii extract obtained in step (1), sodium chloride, and propylene glycol, and stirring for 10 min;
(5) sequentially adding butanediol, dextran sodium sulfate and EDTA, and stirring for 10 min;
(6) adding flos Rosae Rugosae hydrolat and flos Matricariae Chamomillae hydrolat certain ratio, stirring for 5min, and stopping stirring.
8. The method according to claim 6, characterized in that it comprises the steps of:
(1) pulverizing 20g rhizoma Smilacis Bockii, sieving with a third sieve, adding 8 times of 80% ethanol, ultrasonically extracting at 300W for 40min, filtering, repeating for 2 times, mixing filtrates, precipitating overnight, and vacuum filtering; concentrating the filtrate under reduced pressure to obtain extract, drying, and pulverizing to obtain rhizoma Smilacis Bockii extract powder;
(2) adding water with the temperature of 60 ℃ according to the formula proportion into a preparation container, and starting stirring;
(3) adding sodium hyaluronate, stirring to dissolve completely, and stirring for 30 min;
(4) sequentially adding the rhizoma Smilacis Bockii extract obtained in step (1), sodium chloride, and propylene glycol, and stirring for 20 min;
(5) sequentially adding butanediol, dextran sodium sulfate and EDTA, and stirring for 20 min;
(6) adding flos Rosae Rugosae hydrolat and flos Matricariae Chamomillae hydrolat certain ratio, stirring for 10min, and stopping stirring.
9. A method for using a composition with skin whitening and moisturizing effects is characterized in that the method comprises the following steps: the composition is administered daily for at least 2 weeks.
10. Use according to claim 9, characterized in that the method is: the composition is administered daily for at least 4 weeks.
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