CN111658756A

CN111658756A - Plaster for treating complications caused by malignant tumor and preparation method thereof

Info

Publication number: CN111658756A
Application number: CN202010657985.0A
Authority: CN
Inventors: 张玉田
Original assignee: Sinochem Technology Co ltd
Current assignee: Sinochem Technology Co ltd
Priority date: 2020-07-09
Filing date: 2020-07-09
Publication date: 2020-09-15

Abstract

The invention provides a plaster for treating complications caused by malignant tumor and a preparation method thereof; the medicine is prepared from the following medicines in parts by weight: 5-10 parts of prepared monkshood; 20-30 parts of cinnamon; 20-50 parts of dried ginger; 30-50 parts of clove. The plaster for treating the complications caused by malignant tumors, namely the 'yang warming and pain relieving navel treatment plaster', overcomes the defects of oral administration and the defects of narrow application range, inaccurate curative effect and complicated prescription of other external plasters, combines the functions of strengthening body resistance and eliminating pathogenic factors by matching with other 'six-in-one anticancer methods' of oral traditional Chinese medicines, effectively improves the physique of a patient, can be independently applied and used together with radiotherapy and chemotherapy, can increase the curative effect of the radiotherapy and chemotherapy and reduce the side effect of the radiotherapy and chemotherapy, and has low price, exact curative effect, convenient use and popularization value.

Description

Plaster for treating complications caused by malignant tumor and preparation method thereof

Technical Field

The invention relates to the field of biomedicine; in particular to a plaster for treating complications caused by malignant tumor and a preparation method thereof.

Background

At present, malignant tumor becomes the first cause of death of residents due to threat of human health, radiotherapy and chemotherapy are common treatment schemes, and certain damage to normal cells cannot be avoided while tumor cells are killed by radioactive rays and chemotherapeutic drugs.

In recent years, the traditional Chinese medicine plays an increasingly important role in clinical and rehabilitation treatment of tumors, not only can directly inhibit the growth of tumor cells, but also can enhance the immunity of patients to prevent and treat tumor metastasis and recurrence; in addition, the traditional Chinese medicine can enhance sensitivity and efficiency when used in combination with radiotherapy and chemotherapy, and reduce toxic and side effects of radiotherapy and chemotherapy. Cancer is a cancer environment in which the qi of the cells cannot be induced by endogenous deficiency of the original power, namely imbalance of yin and yang, imbalance of balance between the inside and outside of the cells, and inability of the yang qi to cause cell mutation, and is a state of imbalance between the human body and the nature and between the internal five viscera and the six fu-organs of the human body. Therefore, in order to prevent and control and ultimately cure cancer, it is necessary to change the "cancer state" and to change the soil in which "cancer cells" are produced, i.e., the "cancer environment". The Huangdi's internal theory: "yang transforming qi and yin forming". From the biological point of view, cell differentiation and apoptosis are related to cell executive functions and belong to "positive qi", and cell proliferation is related to cell number and body growth and belong to "negative shaping". The formation of tumors in vivo is the specific manifestation of phlegm-dampness accumulation and toxic stasis accumulation caused by yang qi deficiency and constitutional deficiency-cold, i.e., deficiency of origin and excess of superficiality. The deficiency of both the spleen and kidney yang not only causes the basic cause of cancer, but also causes various complications and complications such as abdominal pain, diarrhea, cough, dyspnea, dysmenorrhea, anemia, infection and the like, and the conventional treatment means of cancer further aggravates the state of insufficient yang qi, the reaction of accumulation of yin cold and the aggravation of the complications.

In the medical field, Chinese herbs are known as the most effective means for treating the above complications and complications. The traditional Chinese medicine external treatment method plays an important role in treating tumors and complications thereof. The externally applied plaster has been used for treating diseases from ancient times to present, and has been used for a long time, and Suitao physicians Sun Simiao in Qianjin prescription and Wang \28952providesclear evidence that the internal and external treatment is required for tumor treatment; the Chinese song dynasty dong xuan house uses the word 'cancer' for the first time in the 'wei ji bao shu', and has a discussion of 'cancer is sent with plaster'; the principle of Chinese medicine channel tropism is applied, and the effect of mutual coordination of the medicines is applied to form a large compound of a plurality of medicines so as to exert good effects of the medicines.

The traditional Chinese medicine administration method focuses on oral administration and injection methods for treating complications caused by spleen-kidney yang deficiency of cancer patients, the dosage of the medicine which really reaches a focus is only about one third at best after the medicine is detoxified by liver, and more disadvantageously, the damage of the medicine to the liver and the kidney cannot be avoided by oral administration and injection of the medicine. The externally applied plaster is a commonly used treatment means at present, shows a certain curative effect, but has few research samples, single treatment type and uncertain curative effect, particularly has few long-term curative effect researches, and needs to be widely and deeply clinically researched. The existing common plaster is mainly applied to acupuncture points and has poor absorption. In addition, the plaster for assisting tumor treatment sold in the market has complex formula, complex manufacturing process and poor clinical curative effect.

Disclosure of Invention

The invention aims to provide a plaster for treating complications caused by malignant tumors and a preparation method thereof.

In a first aspect, the invention is realized by the following technical scheme:

the invention relates to a plaster for treating complications caused by malignant tumors, which is prepared from the following medicines in parts by weight: 5-10 parts of prepared monkshood; 20-30 parts of cinnamon; 20-50 parts of dried ginger; 30-50 parts of clove.

Preferably, the medicine is prepared from the following medicines in parts by weight: 10 parts of prepared monkshood, 30 parts of cinnamon, 50 parts of dried ginger and 50 parts of clove.

In a second aspect, the present invention also relates to a preparation method of the plaster for treating complications caused by malignant tumors, which comprises the following steps:

step 1, taking 500 g of vaseline, heating to 90-100 ℃ with strong fire in a pan, and completely melting;

step 2, grinding the components into medicinal powder after taking the components according to the proportion of the components;

step 3, putting the powder into a pot, uniformly mixing, and standing for 3-5 minutes;

step 4, 50 g of honey is taken and put into the decocted plaster to be uniformly mixed;

the plaster is prepared from the following medicines in parts by weight: 10 parts of prepared monkshood, 30 parts of cinnamon, 50 parts of dried ginger and 50 parts of clove.

The invention relates to a clinical application method of a plaster for treating complications caused by malignant tumors, which comprises the following steps: cleaning the skin of the patient at the umbilical region, acupoints on the back or pain part corresponding to diseases, sterilizing with iodine, uniformly applying the prepared ointment on the dressing, then applying on the above parts, taking off after 6-8 hr, and continuously applying the ointment on the next day for half a month as a treatment course.

The plaster for treating the complications caused by the malignant tumor has the main effects that: can be used for treating abdominal pain, abdominal distention, cough, asthma, and dysmenorrhea due to spleen and kidney yang deficiency and cold-dampness stagnation.

The components of the application have the following effects:

the prepared aconite root has pungent and hot properties and toxicity, and the unprocessed aconite root has larger toxicity, and can be generally used after being processed to treat cold symptoms, cold limbs and pain, aversion to cold and cold limbs and soreness;

cortex Cinnamomi has tranquilizing, analgesic, antibacterial, and menstruation promoting effects;

the dried ginger has the effects of warming the middle-jiao to dispel cold, restoring yang to promote blood circulation and warming the lung to eliminate retained fluid;

flos Caryophylli has effects of warming middle energizer, lowering adverse qi, activating qi-flowing, relieving pain, warming kidney, and tonifying yang.

The components involved in the invention also have synergistic effect:

the prepared monkshood returns yang to rescue adverse qi, tonifies fire and strengthens yang, and dispels wind-cold-dampness pathogen as monarch drug; cinnamon has the effects of tonifying fire, supporting yang, guiding fire to the origin, dispelling cold, relieving pain, activating blood and stimulating the menstrual flow. Warming spleen and stomach, removing cold accumulation, and promoting blood circulation; the dried ginger has the functions of warming the middle-jiao and dispelling cold, and restoring yang and promoting blood circulation, and the dried ginger and the monkshood have the functions of warming the middle-jiao and dispelling cold and eliminating dampness as ministerial drugs; clove warms the middle-jiao to descend the adverse flow of qi, promotes the circulation of qi to relieve pain, and brings various medicines to direct the disease as adjuvant and guiding. The four medicines are combined together to achieve the purposes of warming the middle-jiao to dispel cold, and eliminating dampness to relieve pain.

The Chinese medicine plaster for external treatment is prepared with Chinese medicinal materials in certain proportion and through mutual coordination. As the plaster is used for the skin surface thin plaster, medicines with thick smell are taken from the plaster, and the medicines are added to lead the medicine to the group, so as to resolve the stagnation and lead the stagnation to directly reach the focus. Therefore, the medicine can permeate into the skin to produce the effects of diminishing inflammation, relieving pain, promoting blood circulation to remove blood stasis, clearing and activating the channels and collaterals, inducing resuscitation and penetrating bones, dispelling wind and cold and the like. The plaster pasted on the body surface activates nerve endings, expands blood vessels through reflection, promotes local blood circulation, improves the nutrition of peripheral tissues and achieves the purposes of detumescence, antiphlogosis and analgesia. Meanwhile, the medicine permeates to subcutaneous tissues at the affected part through the skin, and the relative advantage of higher medicine concentration is generated locally, so that stronger pharmacological action is exerted. The medicine can penetrate skin and mucous membrane, and enter systemic circulation via blood vessel or lymphatic vessel to produce systemic medicinal effect.

The navel application therapy is one of the external treatment methods in traditional Chinese medicine, and various treatment means are utilized to act on the navel part to regulate qi and blood functions of internal organs of a human body through meridians and collaterals, so that the aims of strengthening body resistance, eliminating evil, regulating yin and yang and curing diseases are fulfilled. Thousands of years of history and clinical practice prove that the navel therapy can treat hundreds of diseases of the whole body, is widely applied to digestive system, respiratory system, urogenital system, endocrine system, nervous system and some difficult and complicated diseases, has the functions of prevention and health care, and has the characteristics of simplicity, convenience, cheapness, test, quickness and the like. The navel application therapy is to apply medicine from the umbilical region of a patient, retain for a certain time, and make the medicine act on the human body through skin absorption to produce the treatment effect. It has the advantages of reliable curative effect, simple method, low cost and safety. Wu Shi Dynasty, the external treatment master responds immediately.

Therefore, the traditional Chinese medicine formula for warming yang and tonifying qi is researched, the plaster is prepared, the plaster is directly applied to a focus through umbilical administration, and the curative effect on complications and complications caused by spleen-kidney yang deficiency of malignant tumors, such as abdominal pain, abdominal distension, dyspepsia, dysmenorrhea, diarrhea, frequent micturition, bone marrow suppression and the like is exact.

In order to illustrate the curative effect of the plaster for treating the complications caused by malignant tumors, the following clinical treatment data are provided: wherein, the navel treatment plaster for warming yang and relieving pain is the plaster for treating complications caused by malignant tumors.

The plaster for treating the complications caused by the malignant tumor has the advantages that the curative effect is clinically approved, the plaster is used by more than 2000 patients in 5 years after hospital agreement and prescription, the effective rate is more than 90%, and no obvious side effect exists; since 12 months and 15 years in 2014, more than 2000 cases of malignant tumor patients have been successfully treated by the navel treatment patch for warming yang and relieving pain, complications caused by spleen-kidney yang deficiency such as abdominal pain, abdominal distension, diarrhea, inappetence, dysmenorrheal and the like are combined, the clinical effective rate is more than 90%, the navel treatment patch becomes an indispensable component of traditional Chinese medicine external treatment by a six-in-one anticancer method, and no obvious toxic or side effect is generated;

in addition, the plaster for treating the complications caused by the malignant tumor is used together with chemotherapeutic drugs, can increase the clinical curative effect, relieve the toxic and side effects of radiotherapy and chemotherapy, enhance the disease resistance of a human body and prevent metastasis and relapse, and has popularization and use values.

The method of the invention has the following advantages:

(1) the plaster for treating the complications caused by malignant tumors, namely the 'yang warming and pain relieving navel treatment plaster', organically combines a transdermal therapy and a meridian therapy, is applied to the navel to treat the complications caused by the tumors, accords with the modern safe, nontoxic and effective cancer treatment direction, and is advocated by tumor patients; by adopting a transdermal administration mode, the medicine can directly reach the focus through the skin and enter the human body circulation to achieve the treatment effect of the whole body without obvious side effect;

(2) the plaster for treating the complications caused by malignant tumor, namely the yang warming and pain relieving navel treatment plaster, avoids the first pass effect of the medicine through the liver, and overcomes the huge damage to the liver and the kidney caused by oral administration and injection; avoids the influence of gastrointestinal pH value, bacteria and enzyme on oral administration, avoids the stimulation of the medicament to the intestines and stomach, does not hurt the spleen and the stomach, and is more suitable for long-term administration of tumor patients, in particular to the patients who suffer from nausea and vomiting and eat the medicament immediately.

(3) The plaster for treating the complications caused by malignant tumors, namely the 'yang warming and pain relieving navel treatment plaster', overcomes the defects of oral administration and the defects of narrow application range, inaccurate curative effect and complicated prescription of other external plasters, combines the functions of strengthening body resistance and eliminating pathogenic factors by matching with other 'six-in-one anticancer methods' of oral traditional Chinese medicines, effectively improves the physique of a patient, can be independently applied and used together with radiotherapy and chemotherapy, can increase the curative effect of the radiotherapy and chemotherapy and reduce the side effect of the radiotherapy and chemotherapy, and has low price, exact curative effect, convenient use and popularization value.

Detailed Description

The present invention will be described in detail with reference to specific examples. It should be noted that the following examples are only illustrative of the present invention, but the scope of the present invention is not limited to the following examples.

Examples

The embodiment relates to a plaster for treating complications caused by malignant tumors, which is prepared from the following medicines in parts by weight: 10 parts of prepared monkshood, 30 parts of cinnamon, 50 parts of dried ginger and 50 parts of clove.

Also relates to a preparation method of the plaster for treating complications caused by malignant tumors, which comprises the following steps:

The components of the application have the following effects:

The components involved in the invention also have synergistic effect:

In this embodiment, the prepared plaster for treating complications caused by malignant tumor is applied to the following cases:

the navel treatment plaster for warming yang and relieving pain in the following cases is a plaster for treating complications caused by malignant tumors.

Case (2):

1. plum women, were born in 1951. Manchu, Chengde county, the city of the city below. The clinical diagnosis in 3 months in 2015 is the hospitalization of the endometrial cancer with the lung multiple metastasis, abdominal pain and a small amount of effusion in the pelvic cavity are combined, the symptom is relieved after 2 courses of auxiliary use of the 'navel treatment patch for warming yang and relieving pain', the focus is reduced, and the patient with tumor lives for 3 years.

2. Mr. Hua, man, born in 1957, Lingyuan city people in Liaoning province, 2 months in 2014 diagnosed as rectal cancer, hospitalization for postoperative pelvic lymph node metastasis, and after 2 courses of auxiliary use of 'warming yang and relieving pain navel treatment patch' are given during chemotherapy, the patient does not have bone marrow suppression side effects, the focus of disease is rechecked completely after one month of treatment, and the patient does not have metastasis and relapse in 5 years so far and lives normally.

3. Plum women, born 1948, san gou town, Chengde county, Chengde City. Hospitalization for malignant lymphoma of the abdominal cavity was diagnosed 10 months in 2015. After the patient is admitted, the 'yang warming and pain relieving navel treatment patch' is used in an auxiliary mode, CHOP scheme chemotherapy is simultaneously carried out for one period of 21 days and six periods in total, toxic and side effects such as bone marrow suppression, liver and kidney function damage and the like do not occur in the chemotherapy period, the focus completely disappears after the chemotherapy, and the patient does not have metastasis and relapse after survival for 4 years.

4. Mr. Wang, men, born in 1966, Pingquan county, diagnosed as the postoperative recurrence hospitalization of colon cancer in 2018, assisted by the therapy of 'warming yang and relieving pain umbilical therapy paste' in combination with chemotherapy, and successfully complete the treatment by inhibiting the bone marrow of the patient by I degree.

5. Mr. prune, male, born in 1946. The pancreatic cancer can not be treated by operation in 2016, and the navel treatment paste capable of warming yang and relieving pain is used in an auxiliary way, and is matched with a high-energy focusing ultrasonic knife to treat the complete disappearance of the focus, so far, the pancreatic cancer survives without relapse.

6. Women, born in 1957. Chengde city Xinglong county large stick village. In 2016, hospitalization of a large amount of abdominal dropsy for peritoneal metastasis of ovarian cancer is diagnosed in 6 months, docetaxel and cisplatin are given for chemotherapy for 8 cycles, and simultaneously, a 'yang warming and pain relieving umbilical therapy patch' is used in an auxiliary mode for relieving symptoms after 2 courses, so that bone marrow suppression and liver and kidney function injury do not occur in the treatment process, and relapse does not occur within 4 years.

7. Birth in 1956, Mr. Gong, male. The towns of the Longding county of Chengde City. The diagnosis in 2016 years 1 is that the renal clear cell carcinoma is removed by operation in local hospitals, biological immunotherapy and chemotherapy are given for consolidation treatment, and a 'yang warming and pain relieving umbilical therapy paste' is used for 6 courses of treatment in an auxiliary way, so that the kidney clear cell carcinoma survives for 4 years, and the living and the working are normal.

8. Mr. Zhao, Man, Chengde, Pingquan county, south fifty family Zhen ren. In 2017, the disease is diagnosed in 11 months, MOPP (metal-oxide-polypropylene) scheme chemotherapy is given to the multiple myeloma for 6 cycles, the symptoms are relieved after 2 courses of auxiliary use of a 'yang warming and pain relieving umbilical therapy patch', and bone marrow suppression does not occur in the treatment period. The consolidation treatment is carried out for 3 years without relapse.

9. Old women, born in 1968, Chengdi City Xinglong county. Cervical cancer stage 3 hospitalization was diagnosed at month 4 of 2015. The operation treatment can not be carried out, the auxiliary use of a 'warming yang and relieving pain navel therapy paste' high-energy focusing ultrasonic knife treatment is given, the disappearance of the tumor focus can be found after 3 months of reexamination, and the metastasis relapse does not exist at present.

10. Mr. Zhang, Man, born in 1957. The diagnosis of 8 months in 2014 is primary liver cancer surgical resection and postoperative chemotherapy, and the auxiliary use of the 'navel treatment paste for warming yang and relieving pain' does not cause myelosuppression and has no transfer recurrence signs till now.

11. Mr. plum, male, born in 1972. In 2015, after 7 months of diagnosis, the pancreatic cancer is treated by a high-energy focused ultrasonic knife in combination with chemotherapy, and after the pancreatic cancer is treated by auxiliary use of a yang-warming pain-relieving umbilical therapy patch, bone marrow suppression does not occur, and metastasis and relapse do not occur until now.

The method of the invention has the following advantages: (1) the plaster for treating the complications caused by malignant tumors, namely the 'yang warming and pain relieving navel treatment plaster', organically combines a transdermal therapy and a meridian therapy, is applied to the navel to treat the complications caused by the tumors, accords with the modern safe, nontoxic and effective cancer treatment direction, and is advocated by tumor patients; by adopting a transdermal administration mode, the medicine can directly reach the focus through the skin and enter the human body circulation to achieve the treatment effect of the whole body without obvious side effect; (2) the plaster for treating the complications caused by malignant tumor, namely the yang warming and pain relieving navel treatment plaster, avoids the first pass effect of the medicine through the liver, and overcomes the huge damage to the liver and the kidney caused by oral administration and injection; avoids the influence of gastrointestinal pH value, bacteria and enzyme on oral administration, avoids the stimulation of the medicament to the intestines and stomach, does not hurt the spleen and the stomach, and is more suitable for long-term administration of tumor patients, in particular to the patients who suffer from nausea and vomiting and eat the medicament immediately. (3) The plaster for treating the complications caused by malignant tumors, namely the 'yang warming and pain relieving navel treatment plaster', overcomes the defects of oral administration and the defects of narrow application range, inaccurate curative effect and complicated prescription of other external plasters, combines the functions of strengthening body resistance and eliminating pathogenic factors by matching with other 'six-in-one anticancer methods' of oral traditional Chinese medicines, effectively improves the physique of a patient, can be independently applied and used together with radiotherapy and chemotherapy, can increase the curative effect of the radiotherapy and chemotherapy and reduce the side effect of the radiotherapy and chemotherapy, and has low price, exact curative effect, convenient use and popularization value.

The foregoing description of specific embodiments of the present invention has been presented. It is to be understood that the present invention is not limited to the specific embodiments described above, and that various changes or modifications may be made by one skilled in the art within the scope of the appended claims without departing from the spirit of the invention.

Claims

1. A plaster for treating complications caused by malignant tumors is characterized by being prepared from the following medicines in parts by weight: 5-10 parts of prepared monkshood; 20-30 parts of cinnamon; 20-50 parts of dried ginger; 30-50 parts of clove.

2. The plaster for treating complications caused by malignant tumors according to claim 1, which is prepared from the following medicines in parts by weight: 10 parts of prepared monkshood, 30 parts of cinnamon, 50 parts of dried ginger and 50 parts of clove.

3. A process for preparing a plaster for the treatment of complications caused by malignant tumors according to claim 1, comprising the steps of: