CN102274295A - Medicament for treating breast diseases and preparation method thereof - Google Patents
Medicament for treating breast diseases and preparation method thereof Download PDFInfo
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- CN102274295A CN102274295A CN2011102037596A CN201110203759A CN102274295A CN 102274295 A CN102274295 A CN 102274295A CN 2011102037596 A CN2011102037596 A CN 2011102037596A CN 201110203759 A CN201110203759 A CN 201110203759A CN 102274295 A CN102274295 A CN 102274295A
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- 239000003814 drug Substances 0.000 title claims abstract description 32
- 208000030270 breast disease Diseases 0.000 title claims abstract description 16
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 16
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000000706 filtrate Substances 0.000 claims abstract description 10
- 241000533985 Silene baccifera Species 0.000 claims abstract description 9
- 238000001914 filtration Methods 0.000 claims abstract description 8
- 239000000203 mixture Substances 0.000 claims abstract description 8
- 238000010438 heat treatment Methods 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 238000003756 stirring Methods 0.000 claims abstract description 6
- 241000628997 Flos Species 0.000 claims description 8
- 239000010231 banlangen Substances 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 5
- 238000000247 postprecipitation Methods 0.000 claims description 5
- 241000245240 Lonicera Species 0.000 claims description 2
- 239000012141 concentrate Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 10
- 230000007774 longterm Effects 0.000 abstract description 3
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 abstract 2
- 238000002156 mixing Methods 0.000 abstract 2
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241000729173 Cirsium japonicum Species 0.000 abstract 1
- 235000003805 Musa ABB Group Nutrition 0.000 abstract 1
- 240000008790 Musa x paradisiaca Species 0.000 abstract 1
- 235000015266 Plantago major Nutrition 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 239000009910 sargent gloryvine Substances 0.000 abstract 1
- 238000002791 soaking Methods 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 208000004396 mastitis Diseases 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 description 3
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 description 3
- 210000005075 mammary gland Anatomy 0.000 description 3
- GYCKQBWUSACYIF-UHFFFAOYSA-N o-hydroxybenzoic acid ethyl ester Natural products CCOC(=O)C1=CC=CC=C1O GYCKQBWUSACYIF-UHFFFAOYSA-N 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 208000009146 rhinoscleroma Diseases 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 208000028399 Critical Illness Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicament for treating breast diseases and a preparation method thereof. The medicament is prepared from the following raw materials in part by weight: 25 to 35 parts of Mongolian dandelion herb, 25 to 35 parts of sargentgloryvine stem, 10 to 20 parts of honeysuckle flower, 25 to 35 parts of cucubalus baccifer linn., 25 to 35 parts of indigowoad root, 25 to 45 parts of Japanese thistle herb or root and 25 to 35 parts of plantain herb. The preparation method comprises the following steps of: mixing the raw materials in mass ratio fully, soaking in 1,000 to 1,000 milliliters of warm water at the temperature of between 40 and 60 for 1 to 1.5 hours; decocting the soaked mixture for 1 to 1.5 hours, and filtering for the first time; adding filter residues into the water, decocting for 40 minutes, and filtering for the second time; and mixing filtrate obtained at two times, heating, concentrating, adding nipagin ethanol while the concentrated filtrate is hot, namely adding 3 grams of nipagin ethanol into 950 milliliters of concentrated filtrate, stirring uniformly, precipitating, extracting supernatant, filtering, and adding the water to 1,000 milliliters to obtain the medicament. The medicament is good in a short-term curative effect, stable in a long-term curative effect and convenient to use.
Description
Technical field
The invention belongs to field of medicaments, relate in particular to a kind of medicine that is used for the treatment of mastopathy, also relate to its preparation method simultaneously.
Background technology
Allowing the agonizing breast disease of women be a kind of commonly encountered diseases, frequently-occurring disease, is the able-bodied principal disease of harm women, common as mastitis, cyclomastopathy, enclosed mass scleroma pain.Its paathogenic factor more complicated, as treat untimely or malpractice, just pathological changes may take place, cause life danger at any time.
At present, the medicine of treatment mastopathy mainly contains oral and external, and oral based on Western medicine, Western medicine mainly is an antiphlogistic antibacterial, and side effect is big, and easily recurrence.The external curing poor effect.
Summary of the invention
The object of the present invention is to provide that a kind of short term efficacy is good, long-term efficacy is stable, and the medicine that is used for the treatment of mastopathy easy to use.
Another object of the present invention is to provide this to be used for the treatment of the preparation method of the medicine of mastopathy.
A kind of medicine that is used for the treatment of mastopathy of the present invention, each raw material components consumption is for all to have better curative effect at following weight range:
Herba Taraxaci 25-35 part, Caulis Sargentodoxae 25-35 part, Flos Lonicerae 10-20 part, Cucubalus baccifer 25-35 part, Radix Isatidis 25-35 part, Radix Cirsii Japonici 25-45 part, Herba Plantaginis 25-35 part.
Preferably: 30 parts of Herba Taraxacis, 30 parts of Caulis Sargentodoxae, 15 parts of Flos Loniceraes, 30 parts of Cucubalus baccifer, 20 parts of Radix Isatidis, 35 parts of Radix Cirsii Japonicis, 30 parts of Herba Plantaginiss.
A kind of preparation method that is used for the treatment of the medicine of mastopathy of the present invention may further comprise the steps:
(1) in g, according to the above ratio medicine is fully mixed, soaked 1-1.5 hour with 40-60 ℃ warm water 1000-1000ml;
(2) soaked mixture decoction after 1-1.5 hour, is filtered for the first time;
(3) filtering residue adds entry again, decocts after 40 minutes, carries out the second time and filters;
(4) merge twice filtrate, heating concentrates, and adds nipalgin ethanol while hot, and every 950ml concentrated filtrate adds nipalgin ethanol 3g, stirs, and treats that its post precipitation gets the clear liquid on upper strata, refilters, and adds water to 1000ml promptly.
Medicine of the present invention compared with prior art, has tangible beneficial effect, as can be known from the above technical solutions: the present invention utilizes natural drugs such as Herba Taraxaci, Caulis Sargentodoxae, Flos Lonicerae, Cucubalus baccifer, Radix Isatidis, Radix Cirsii Japonici, Herba Plantaginis to be raw material, utilizes co-action for treating mastitis between each medicine, cyclomastopathy, enclosed mass scleroma pain.Short term efficacy is good, long-term efficacy is stable, and easy to use.The present invention has heat-clearing and toxic substances removing, mass dissipating and swelling eliminating, promoting blood circulation to remove obstruction in the collateral, removing pathogenic heat from blood and inducing diuresis.It is drawn materials easily, and preparation method is simple, easy operating, is fit to large-scale production.
The specific embodiment
Below further set forth the beneficial effect of medicine of the present invention by testing example.
The test example: the clinical observation of medicine of the present invention
1. case is selected
Treatment case 150 examples, wherein: age 50--60 one full year of life 38 example, 30--50 one full year of life 112 example.Medical diagnosis on disease is diagnosed according to diseases related diagnostic criterias such as doctor trained in Western medicine mastitis, cyclomastopathy, mammary gland benign tumors.
Mastitis 50 examples, cyclomastopathy 50 examples, mammary gland benign tumor 50 examples.
2. Therapeutic Method
Get embodiment 1 gained medicine, for oral administration: three times on the one, each 100ml.3 was 1 course of treatment, pasted in 1 day 1.State of an illness the lighter, 1～2 course of treatment; Critically ill patient needs 3 courses of treatment altogether.
3. curative effect determinate standard
With improvement degree such as symptom, body cards is curative effect determinate standard, is divided into:
Clinical cure: symptom all disappears;
Produce effects: symptom has clear improvement;
Effectively: symptom has certain improvement.
Invalid: and compare the each side no change before the medication.
4. therapeutic effect
| The sick kind | Clinical cure | Produce effects | Effectively | Invalid | Total effective rate |
| Mastitis | 47 | 3 | 0 | 0 | 100 % |
| Cyclomastopathy | 47 | 3 | 0 | 0 | 100 % |
| Mammary gland benign tumor | 47 | 1 | 2 | 0 | 100 % |
Clinical cure 141 examples, produce effects 7 examples, effective 2 examples, invalid do not have.Clinical cure rate 94 %, obvious effective rate 4.7 %, effective percentage 1.3%, total effective rate 100 %.All cases have no adverse reaction.
The clinical cure personnel tracking is followed up a case by regular visits to 50 people, do not see recurrence in 2 years.
Illustrate the preparation method of this medicine by following examples.
Embodiment 1:
A kind of preparation method that is used for the treatment of the medicine of mastopathy may further comprise the steps:
(1) Herba Taraxaci 30g, Caulis Sargentodoxae 30g, Flos Lonicerae 15g, Cucubalus baccifer 30g, Radix Isatidis 20g, Radix Cirsii Japonici 35g, Herba Plantaginis 30g are fully mixed, soaked 1.5 hours with 40 ℃ warm water 1000;
(2) soaked mixture decoction after 1.5 hours, is filtered;
(3) filtering residue adds water 500ml again, decocts after 40 minutes, filters;
(4) merge twice filtrate, heating is concentrated to 950ml, adds ethyl hydroxybenzoate 3g while hot, stirs, and treats that its post precipitation gets the clear liquid on upper strata, refilters, and adds water 1000 ml promptly.
Embodiment 2:
A kind of preparation method that is used for the treatment of the medicine of mastopathy may further comprise the steps:
(1) Herba Taraxaci 25g, Caulis Sargentodoxae 25g, Flos Lonicerae 10g, Cucubalus baccifer 25g, Radix Isatidis 25g, Radix Cirsii Japonici 25g, Herba Plantaginis 25g fully mix, and soak 1 hour with 60 ℃ warm water 1100ml;
(2) soaked mixture decoction after 1 hour, is filtered;
(3) filtering residue adds water 600ml again, decocts after 40 minutes, filters;
(4) merge twice filtrate, heating is concentrated to 950ml, adds ethyl hydroxybenzoate 3g while hot, stirs, and treats that its post precipitation gets the clear liquid on upper strata, refilters, and adds water 1000 ml promptly.
Embodiment 3:
A kind of preparation method that is used for the treatment of the medicine of mastopathy may further comprise the steps:
(1) Herba Taraxaci 35g, Caulis Sargentodoxae 35g, Flos Lonicerae 20g, Cucubalus baccifer 35g, Radix Isatidis 35g, Radix Cirsii Japonici 45g, Herba Plantaginis 35g fully mix, and soak 1.2 hours with 50 ℃ warm water 1000ml;
(2) soaked mixture decoction after 1.2 hours, is filtered;
(3) filtering residue adds water 550ml again, decocts after 40 minutes, filters;
(4) merge twice filtrate, heating is concentrated to 950ml, adds ethyl hydroxybenzoate 3g while hot, stirs, and treats that its post precipitation removes the clear liquid on upper strata, refilters, and adds water 1000 ml promptly.
The above, it only is preferred embodiment of the present invention, be not that the present invention is done any pro forma restriction, any technical solution of the present invention content that do not break away from,, all still belong in the scope of technical solution of the present invention any simple modification, equivalent variations and modification that above embodiment did according to technical spirit of the present invention.
Claims (3)
1. medicine that is used for the treatment of mastopathy is made by the following weight parts raw material:
Herba Taraxaci 25-35 part, Caulis Sargentodoxae 25-35 part, Flos Lonicerae 10-20 part, Cucubalus baccifer 25-35 part, Radix Isatidis 25-35 part, Radix Cirsii Japonici 25-45 part, Herba Plantaginis 25-35 part.
2. the medicine that is used for the treatment of mastopathy as claimed in claim 1 is made by the following weight parts raw material:
30 parts of Herba Taraxacis, 30 parts of Caulis Sargentodoxae, 15 parts of Flos Loniceraes, 30 parts of Cucubalus baccifer, 20 parts of Radix Isatidis, 35 parts of Radix Cirsii Japonicis, 30 parts of Herba Plantaginiss.
3. the preparation method that is used for the treatment of the medicine of mastopathy as claimed in claim 1 or 2 may further comprise the steps:
(1) in g, according to the above ratio medicine is fully mixed, soaked 1-1.5 hour with 40-60 ℃ warm water 1000-1000ml;
(2) soaked mixture decoction after 1-1.5 hour, is filtered for the first time;
(3) filtering residue adds entry again, decocts after 40 minutes, carries out the second time and filters;
(4) merge twice filtrate, heating concentrates, and adds nipalgin ethanol while hot, and every 950ml concentrated filtrate adds nipalgin ethanol 3g, stirs, and treats that its post precipitation gets the clear liquid on upper strata, refilters, and adds water to 1000ml promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110203759.6A CN102274295B (en) | 2011-07-20 | 2011-07-20 | Medicament for treating breast diseases and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110203759.6A CN102274295B (en) | 2011-07-20 | 2011-07-20 | Medicament for treating breast diseases and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102274295A true CN102274295A (en) | 2011-12-14 |
| CN102274295B CN102274295B (en) | 2014-04-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110203759.6A Expired - Fee Related CN102274295B (en) | 2011-07-20 | 2011-07-20 | Medicament for treating breast diseases and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102274295B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526416A (en) * | 2012-02-10 | 2012-07-04 | 李宪孟 | Traditional Chinese medicine for treating breast carcinoma |
| CN108888694A (en) * | 2018-09-21 | 2018-11-27 | 程发英 | A kind of Chinese medicine composition and preparation method thereof with antitumaous effect |
| CN109876063A (en) * | 2019-03-20 | 2019-06-14 | 嵇树红 | The Chinese medicine composition for treating lump |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229357A (en) * | 2008-01-30 | 2008-07-30 | 胡永旺 | Chinese traditional medicine for treating mammary glands hyperplasia |
-
2011
- 2011-07-20 CN CN201110203759.6A patent/CN102274295B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229357A (en) * | 2008-01-30 | 2008-07-30 | 胡永旺 | Chinese traditional medicine for treating mammary glands hyperplasia |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526416A (en) * | 2012-02-10 | 2012-07-04 | 李宪孟 | Traditional Chinese medicine for treating breast carcinoma |
| CN108888694A (en) * | 2018-09-21 | 2018-11-27 | 程发英 | A kind of Chinese medicine composition and preparation method thereof with antitumaous effect |
| CN109876063A (en) * | 2019-03-20 | 2019-06-14 | 嵇树红 | The Chinese medicine composition for treating lump |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102274295B (en) | 2014-04-02 |
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Granted publication date: 20140402 |