CN111513000A - 青蒿素在消除养殖鱼类体内磺胺类药物残留中的应用 - Google Patents
青蒿素在消除养殖鱼类体内磺胺类药物残留中的应用 Download PDFInfo
- Publication number
- CN111513000A CN111513000A CN202010267765.7A CN202010267765A CN111513000A CN 111513000 A CN111513000 A CN 111513000A CN 202010267765 A CN202010267765 A CN 202010267765A CN 111513000 A CN111513000 A CN 111513000A
- Authority
- CN
- China
- Prior art keywords
- artemisinin
- sulfamethoxazole
- elimination
- sulfonamide
- cultured fishes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000251468 Actinopterygii Species 0.000 title claims abstract description 28
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 title claims abstract description 26
- 229960004191 artemisinin Drugs 0.000 title claims abstract description 26
- 229930101531 artemisinin Natural products 0.000 title claims abstract description 22
- 230000008030 elimination Effects 0.000 title claims abstract description 20
- 238000003379 elimination reaction Methods 0.000 title claims abstract description 20
- 125000000565 sulfonamide group Chemical group 0.000 title claims abstract description 8
- JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 claims abstract description 32
- 229960005404 sulfamethoxazole Drugs 0.000 claims abstract description 28
- 229940124530 sulfonamide Drugs 0.000 claims abstract description 15
- 150000003456 sulfonamides Chemical class 0.000 claims abstract description 12
- 230000037396 body weight Effects 0.000 claims description 4
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- 241000252498 Ictalurus punctatus Species 0.000 description 31
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- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 9
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- 229910052757 nitrogen Inorganic materials 0.000 description 3
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 description 3
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 2
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- 241000404975 Synchiropus splendidus Species 0.000 description 2
- 241000376029 Tachysurus fulvidraco Species 0.000 description 2
- 241000276707 Tilapia Species 0.000 description 2
- 238000007664 blowing Methods 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000000589 high-performance liquid chromatography-mass spectrometry Methods 0.000 description 2
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- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 2
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- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
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- HQVFCQRVQFYGRJ-UHFFFAOYSA-N formic acid;hydrate Chemical compound O.OC=O HQVFCQRVQFYGRJ-UHFFFAOYSA-N 0.000 description 1
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- 235000013372 meat Nutrition 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 239000008055 phosphate buffer solution Substances 0.000 description 1
- 239000012286 potassium permanganate Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
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- 238000009210 therapy by ultrasound Methods 0.000 description 1
- 206010043554 thrombocytopenia Diseases 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K61/00—Culture of aquatic animals
- A01K61/10—Culture of aquatic animals of fish
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K61/00—Culture of aquatic animals
- A01K61/10—Culture of aquatic animals of fish
- A01K61/13—Prevention or treatment of fish diseases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
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- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Marine Sciences & Fisheries (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010267765.7A CN111513000B (zh) | 2020-04-10 | 2020-04-10 | 青蒿素在消除养殖鱼类体内磺胺类药物残留中的应用 |
Applications Claiming Priority (1)
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CN202010267765.7A CN111513000B (zh) | 2020-04-10 | 2020-04-10 | 青蒿素在消除养殖鱼类体内磺胺类药物残留中的应用 |
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CN111513000A true CN111513000A (zh) | 2020-08-11 |
CN111513000B CN111513000B (zh) | 2021-08-03 |
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CN202010267765.7A Active CN111513000B (zh) | 2020-04-10 | 2020-04-10 | 青蒿素在消除养殖鱼类体内磺胺类药物残留中的应用 |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4374826A (en) * | 1980-07-21 | 1983-02-22 | Pfizer Inc. | Sulfonamide compositions |
DE3613794A1 (de) * | 1986-04-24 | 1987-10-29 | Frank Joachim Mueller | Verfahren zum nachweis von antibiotika- und sulfonamidrueckstaenden in biologischen fluessigkeiten oder nahrungsmitteln |
US5064637A (en) * | 1989-05-30 | 1991-11-12 | Board Of Regents, The University Of Texas System | Substituted sulfonamide derivatives which inhibit allergic reactions |
CN101571541A (zh) * | 2009-06-01 | 2009-11-04 | 北京望尔康泰生物技术有限公司 | 检测磺胺类药物的酶联免疫试剂盒及其方法 |
JP2013240296A (ja) * | 2012-05-21 | 2013-12-05 | Okabe Co Ltd | 魚介類及び海藻類の複合養殖装置と、その複合養殖方法 |
CN110483546A (zh) * | 2019-08-28 | 2019-11-22 | 西南大学 | 二氢青蒿素磺胺类衍生物、合成方法与应用 |
-
2020
- 2020-04-10 CN CN202010267765.7A patent/CN111513000B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4374826A (en) * | 1980-07-21 | 1983-02-22 | Pfizer Inc. | Sulfonamide compositions |
DE3613794A1 (de) * | 1986-04-24 | 1987-10-29 | Frank Joachim Mueller | Verfahren zum nachweis von antibiotika- und sulfonamidrueckstaenden in biologischen fluessigkeiten oder nahrungsmitteln |
US5064637A (en) * | 1989-05-30 | 1991-11-12 | Board Of Regents, The University Of Texas System | Substituted sulfonamide derivatives which inhibit allergic reactions |
CN101571541A (zh) * | 2009-06-01 | 2009-11-04 | 北京望尔康泰生物技术有限公司 | 检测磺胺类药物的酶联免疫试剂盒及其方法 |
JP2013240296A (ja) * | 2012-05-21 | 2013-12-05 | Okabe Co Ltd | 魚介類及び海藻類の複合養殖装置と、その複合養殖方法 |
CN110483546A (zh) * | 2019-08-28 | 2019-11-22 | 西南大学 | 二氢青蒿素磺胺类衍生物、合成方法与应用 |
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CN111513000B (zh) | 2021-08-03 |
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Application publication date: 20200811 Assignee: YUNNAN MORALGOODS AGRICULTURE AND TECHNOLOGY CO.,LTD. Assignor: YANGTZE RIVER FISHERIES Research Institute CHINESE ACADEMY OF FISHERY SCIENCES Contract record no.: X2023980036325 Denomination of invention: Application of artemisinin in eliminating sulfonamide residues in cultured fish Granted publication date: 20210803 License type: Common License Record date: 20230608 |
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Application publication date: 20200811 Assignee: Yunnan Jikun Ecological Agriculture Co.,Ltd. Assignor: YANGTZE RIVER FISHERIES Research Institute CHINESE ACADEMY OF FISHERY SCIENCES Contract record no.: X2023420000254 Denomination of invention: Application of artemisinin in eliminating sulfonamide residues in cultured fish Granted publication date: 20210803 License type: Common License Record date: 20230719 Application publication date: 20200811 Assignee: Qianlong Innovation Agriculture Development Yunnan Co.,Ltd. Assignor: YANGTZE RIVER FISHERIES Research Institute CHINESE ACADEMY OF FISHERY SCIENCES Contract record no.: X2023420000250 Denomination of invention: Application of artemisinin in eliminating sulfonamide residues in cultured fish Granted publication date: 20210803 License type: Common License Record date: 20230719 |
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Application publication date: 20200811 Assignee: Yunnan Benyi Modern Agricultural Development Co.,Ltd. Assignor: YANGTZE RIVER FISHERIES Research Institute CHINESE ACADEMY OF FISHERY SCIENCES Contract record no.: X2023420000255 Denomination of invention: Application of artemisinin in eliminating sulfonamide residues in cultured fish Granted publication date: 20210803 License type: Common License Record date: 20230720 |
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Application publication date: 20200811 Assignee: Hubei Xianzhirun Ecological Agriculture Technology Development Co.,Ltd. Assignor: YANGTZE RIVER FISHERIES Research Institute CHINESE ACADEMY OF FISHERY SCIENCES Contract record no.: X2023980041142 Denomination of invention: Application of artemisinin in eliminating sulfonamide residues in cultured fish Granted publication date: 20210803 License type: Common License Record date: 20230904 |