CN111481178B - Quantitative shallow feeling comprehensive analysis early warning system and method and application - Google Patents
Quantitative shallow feeling comprehensive analysis early warning system and method and application Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4824—Touch or pain perception evaluation
- A61B5/4827—Touch or pain perception evaluation assessing touch sensitivity, e.g. for evaluation of pain threshold
- A61B5/483—Touch or pain perception evaluation assessing touch sensitivity, e.g. for evaluation of pain threshold by thermal stimulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
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Abstract
The invention relates to a quantitative shallow feeling comprehensive analysis early warning system and a method and application, wherein the system comprises a probe, the probe comprises an upper cover, a cold-heat exchange device, a probe shell and an infrared silicon lens, one end of the cold-heat exchange device is sleeved with the probe shell, the other end of the cold-heat exchange device is sleeved with the upper cover, and the infrared silicon lens is arranged on the end face of the probe shell; the cold-heat exchange device is a cylindrical heat dissipation shell with a heat dissipation fin at one end, a contact head arranged along the axis direction of the cylinder is arranged in the cylindrical heat dissipation shell, an infrared temperature sensor and a microprocessor are arranged at one end of the contact head, and a pressure sensor is arranged at the other end of the contact head; the probe shell is internally provided with a temperature detection device which is clung to the infrared silicon lens, and the infrared silicon lens is also connected with the temperature changing device and the pressure sensor through a heat conduction spring and a force conduction spring respectively. The invention can quantitatively analyze the self-peripheral superficial paresthesia condition, effectively protect the safety and detect the specific condition, and can be used as auxiliary medical equipment in the cold therapy and heat therapy process.
Description
Technical Field
The invention relates to a system for measuring peripheral sensory system, in particular to a quantitative shallow feeling comprehensive analysis early warning system and method and application. Belongs to the field of medical appliances.
Background
With clinical needs and urgent needs of scientific research in departments such as plastic surgery, burn surgery and neurology, development of a quantitative analysis system for superficial sensory functions of a subject is particularly important. Although the temperature sensing analyzer which is used in the medical and scientific research fields can quantitatively measure the threshold value (cold, hot, cold pain and hot pain) to a certain extent, due to the fact that the temperature is recorded by clicking a mouse by hand, time errors can exist between the occurrence of protective reaction (such as shrinkage of hands and foot) when the pain threshold value is reached and the confirmation of clicking the mouse, so that the quantification is inaccurate and the probe temperature when clicking the mouse can only be recorded instead of the accumulated temperature of actual skin. In addition, when the accumulated skin temperature exceeds the safe temperature, scalding or frostbite can be caused, for the crowd with abnormal peripheral sensation, especially for the crowd with insensitive sensation or lack of sensation (such as congenital spinal laceration), a testing system which can quantitatively analyze and play a role in monitoring and early warning is needed, the safety of the skin of the crowd is protected and early warned through warning, and the heat dissipation capacity of the skin is comprehensively judged, so that the effects of identification and auxiliary treatment on patients can be better achieved. Finally, conventional quantitative analysis systems for superficial sensory functions cannot archive historical test data of the skin to reflect actual course changes of the skin.
Disclosure of Invention
The purpose of the invention is that: in order to overcome the problems in the prior art, a quantitative shallow feeling comprehensive analysis and early warning system and a quantitative shallow feeling comprehensive analysis and early warning method are provided, and one of the purposes is as follows: the accumulated skin temperature can be monitored in real time; the second purpose is: an index for judging the self-protective ability of the skin, such as measuring the thermal pain threshold when receiving heating from constant temperature or the accumulated skin temperature when generating self-protective reaction (hands-like reaction); the third purpose is: the skin temperature of the skin at a specific part can be measured, and the skin temperature measuring device can be used as auxiliary medical equipment in the cold therapy and heat therapy process, so that the skin safety protection of special people is realized; the fourth purpose is: the system can quantitatively analyze the abnormal condition of the peripheral shallow feeling (pain and temperature sensation) of the body and effectively protect the safety; the fifth purpose is: through setting up the support, can liberate both hands when the survey, make the doctor concentrate on the collection of survey index, increase systematic ground stability, avoid the operation to bring pressure sensor's change. The sixth purpose is: the application of the quantitative shallow feeling comprehensive analysis early warning system is provided.
The technical scheme adopted by the invention is as follows: the quantitative shallow feeling comprehensive analysis early warning system comprises a probe, wherein the probe comprises an upper cover, a cold and hot exchange device, a probe shell and an infrared silicon lens, one end of the cold and hot exchange device is sleeved with the probe shell, the other end of the cold and hot exchange device is sleeved with the upper cover, and the infrared silicon lens is arranged on the end face of the probe shell; the cold-heat exchange device is a cylindrical heat dissipation shell with a heat dissipation fin at one end, a contact head arranged along the axis direction of the cylinder is arranged in the cylindrical heat dissipation shell, an infrared temperature sensor and a microprocessor are arranged at one end of the contact head, and a pressure sensor is arranged at the other end of the contact head; the probe shell is cylindrical, a temperature detection device is arranged in the probe shell, the temperature detection device is annular and is clung to the infrared silicon lens, and the infrared silicon lens is also connected with the temperature changing device and the pressure sensor through a heat conduction spring and a force conduction spring respectively; the temperature changing device and the contact head are correspondingly positioned on the same axis, the temperature changing device and the cold-hot exchange device form an environment generating unit, the environment generating unit is electrically connected with the microprocessor through the temperature control relay, and the infrared temperature sensor, the pressure sensor and the temperature detecting device are respectively electrically connected with the microprocessor.
Further, the quantitative shallow feeling comprehensive analysis early warning system also comprises a direct current power supply and a PC, wherein the direct current power supply and the PC are arranged outside the probe, an external wiring hole is formed in the end face of the upper cover, the direct current power supply supplies power to the environment generation unit and the microprocessor through the external wiring hole, and the microprocessor is in electric signal connection with the PC.
Further, the contact head is cylindrical, an inner wiring hole is formed in the outer wall of the cylinder, and the pressure sensor and the temperature detection device are respectively and electrically connected with the microprocessor through the inner wiring hole.
Further, the temperature changing device is a semiconductor refrigerating sheet, the semiconductor refrigerating sheet and the pressure sensor are of annular structures, the pressure sensor is sleeved on the contact head, a plurality of force guiding springs are uniformly distributed on the outer side of the contact head along the axial direction of the contact head, one end of each force guiding spring is fixedly connected with the pressure sensor, the other end of each force guiding spring is tightly attached to the infrared silicon lens, one or more heat guiding springs are arranged, one end of each heat guiding spring is fixed on the semiconductor refrigerating sheet, and the other end of each heat guiding spring is tightly attached to the infrared silicon lens and is positioned on the inner side of each force guiding spring; the temperature detection device is an annular thermistor, the diameter of the annular thermistor is larger than that of the pressure sensor, the diameter of the semiconductor refrigerating sheet is the same as that of the contact head, and the annular thermistor, the semiconductor refrigerating sheet, the pressure sensor and the contact head are coaxial.
Further, a bracket fixing hole is formed in the side wall of the upper cover; threads are arranged in the bracket fixing holes.
Further, the support fixing hole is connected with a support through threads, the support consists of a support seat and a support aluminum core supporting tube, one end of the support aluminum core supporting tube is fixed on the support seat, and the other end of the support aluminum core supporting tube is detachably connected with the support fixing hole through threads.
Further, the probe is made of titanium alloy material; the infrared silicon lens has a transmittance of more than 90% to infrared light and a heat conduction coefficient of 150; The heat conduction spring is made of copper material, and the heat conductivity is 410/>; The elastic coefficient/>, of the force guiding springIs 0.4/>The displacement of the spring is related to the pressure as/>Wherein/>For pressure acting on the pressure sensor,/>Is the elastic coefficient of the spring,/>Is the displacement of the spring.
Further, the temperature rising and falling speed of the infrared silicon lens is 1 ℃/s; the temperature changing device is a semiconductor refrigerating sheet, and the temperature changing device, the pressure sensor and the cold-heat exchange device are hollow structures and provide a light path between the infrared silicon lens and the infrared temperature sensor.
Further, a quantitative shallow feeling comprehensive analysis and early warning method comprises the following specific steps:
(1) Setting the probe to a temperature changing mode through a PC, setting the initial temperature of the test to 30-32 ℃, and then transmitting the initial temperature to a microprocessor;
(2) After receiving the temperature changing instruction, the microprocessor changes the temperature of the contact surface of the temperature changing device and the heat conducting spring through the temperature control relay, and then the temperature is conducted to the infrared silicon lens through the heat conducting spring, so that the infrared silicon lens is changed in the temperature range of-5 ℃ to 50 ℃; the temperature of the infrared silicon lens is monitored in real time through a temperature detection device, and the monitored temperature is transmitted to the microprocessor;
(3) The upper limit of the safe temperature is set to 44 ℃ through a PC, the lower limit of the safe temperature is set to 10.8 ℃, the detected object is detected through an infrared silicon lens of a probe, the temperature of the detected object is detected through the infrared silicon lens by an infrared temperature sensor 1, and the detected temperature is transmitted to a microprocessor; the microprocessor transmits the data detected by the temperature detection device and the infrared temperature sensor to the PC for data storage, data analysis and filing;
(4) When the temperature of the measured object reaches a threshold value, an audible and visual alarm device in the PC sends out early warning to remind the user of paying attention, and the duration is 30s; when the infrared temperature sensor detects that the accumulated temperature of the measured object exceeds the warning temperature for more than 30 seconds, the microprocessor sends an alarm signal and automatically changes the voltages at the two ends of the temperature changing device to perform a cold and heat source re-heating mode, so that the temperature of the measured object returns to a safe temperature range of 30-32 ℃;
(5) If the infrared silicon lens moves, the pressure signal is transmitted to the pressure sensor through the force guiding spring, the pressure sensor transmits the movement information of the detected infrared silicon lens to the microprocessor, and the data detected by the microprocessor is transmitted to the PC for data storage and data analysis and profiling.
Further, the quantitative shallow feeling comprehensive analysis early warning system is used as a heat source or a cold source and becomes auxiliary medical equipment for carrying out heat treatment or cold treatment; or as an instrument for measuring nerve conduction; or an instrument for precise determination of the melting point of a substance; or an instrument for thermodynamic identification of material purity: or an instrument for quality identification of temperature sensitive materials and thermolabile materials.
The invention has the advantages that: the system can quantitatively analyze the abnormal conditions of the superficial peripheral sensation (pain and temperature sensation) of the body, effectively protect the safety, detect the specific conditions related to the skin and assist medical equipment in the cold therapy and thermotherapy process; the specific functions are as follows: 1) The temperature changing device, the heat conducting spring, the infrared silicon lens, the temperature detecting device and the infrared sensor are utilized to realize the control of temperature changing and constant temperature, the function of measuring (cold, hot, cold pain and hot pain) threshold values in the probe temperature changing mode is improved, the accuracy and the application range of quantitative measurement (cold, hot, cold pain and hot pain) threshold values are improved, the accumulated skin temperature is monitored in real time, early warning of setting the upper limit and the lower limit of skin safety temperature and timely skin rewarming after early warning are established through the microprocessor and the PC, and skin secondary damage caused by the detection process is prevented; )
2) The index for judging the self-protection ability of the skin can be quantitatively obtained through the force guiding spring and the pressure sensor, and the skin accumulation temperature is measured when the constant temperature heating source (a milder heat source can not generate obvious protective reaction when contacting the skin) is received for heating, and the thermal pain threshold or the skin accumulation temperature is generated when the self-protection reaction (similar hands shrinkage reaction) is generated.
3) The temperature change by the temperature changing device can be used for auxiliary medical equipment in the cold therapy and heat therapy process, and the skin safety protection of the crowd with hypoesthesia, dullness or disappearance of the periphery is realized. Meanwhile, the system can also be used for measuring nerve conduction, material melting point and other accurate measurement, and provides a wide application prospect for probe testing.
4) By using the bracket, the two hands are liberated during measurement, so that doctors can concentrate on the acquisition of measurement indexes. The stability of the system is improved, the change of the pressure sensor caused by operation is avoided, and the accuracy of test data is improved.
5) The PC can be used for filing, so that the disease course change of the patient can be conveniently analyzed and counted, and reasonable decision can be made for the disease condition of the patient. Meanwhile, combining with a nineteenth method, quantitatively obtaining the initial temperature of the skin, and comprehensively judging the heat dissipation capacity of the skin or peripheral nerve vascular diseases.
Drawings
The invention is further illustrated, but not limited, by the following figures and examples.
FIG. 1 is a schematic diagram of the present invention;
FIG. 2 is a block diagram of the invention after it has been integrally installed;
fig. 3 is a schematic view of a specific structure of the present invention.
In the figure, 1, an infrared temperature sensor; 2. a pressure sensor; 3. an environment generation unit; 4. a temperature changing device; 5. a cold-heat exchange device; 5-1, cooling fins; 5-2, a cylindrical heat dissipation shell; 5-3, internal wiring holes; 5-4, a contact head; 6. a temperature control relay; 7. a temperature detecting device; 8. a direct current power supply; 9. a microprocessor; 10. a PC; 11. an infrared silicon lens; 12. a probe housing; 13; a heat conduction spring; 14. a force-guiding spring; 15. an external wiring hole; 16. a bracket fixing hole; 17. and (5) an upper cover.
Detailed Description
Example 1
As shown in fig. 1, 2 and 3, the quantitative shallow feeling comprehensive analysis early warning system comprises a probe, wherein the probe comprises an upper cover 17, a cold and heat exchange device 5, a probe shell 12 and an infrared silicon lens 11, one end of the cold and heat exchange device 5 is sleeved with the probe shell 12, the other end of the cold and heat exchange device is sleeved with the upper cover 17, and the infrared silicon lens 11 is arranged on the end face of the probe shell 12; the cold-heat exchange device 5 is a cylindrical heat dissipation shell 5-2 with a heat dissipation fin 5-1 at one end, a contact head 5-4 arranged along the axis direction of the cylinder is arranged in the cylindrical heat dissipation shell 5-2, an infrared temperature sensor 1 and a microprocessor 9 are arranged at one end of the contact head 5-4, and a pressure sensor 2 is arranged at the other end of the contact head; the probe shell 12 is cylindrical, a temperature detection device 7 is arranged in the probe shell, the temperature detection device 7 is annular and is clung to the infrared silicon lens 11, and the infrared silicon lens 11 is also connected with the temperature changing device 4 and the pressure sensor 2 through a heat conduction spring 13 and a force conduction spring 14 respectively; the temperature changing device 4 and the contact heads 5-4 are correspondingly positioned on the same axis, the temperature changing device 4 and the cold-heat exchange device form an environment generating unit 3, the environment generating unit 3 is electrically connected with the microprocessor 9 through the temperature control relay 6, and the infrared temperature sensor 1, the pressure sensor 2 and the temperature detecting device 7 are respectively electrically connected with the microprocessor 9.
When the system works, the infrared sensor detects the temperature of an object to be detected outside the infrared silicon lens 11 through the infrared silicon lens 11, measures the temperature of the infrared silicon lens in real time through the temperature detection device, and can empty the temperature of the infrared silicon lens through the temperature changing device; because the infrared temperature sensor and the microprocessor are placed in the radiator cavity, the infrared silicon lens has high transmittance to infrared light, so that the temperature change of the infrared silicon lens has little influence on the infrared temperature sensor. The microprocessor collects data of the thermistor, the pressure sensor and the infrared temperature sensor to make processing judgment. While the heat and cold exchange device 5 provides a stable temperature environment for the microprocessor.
Example 2
On the basis of embodiment 1, as shown in fig. 1, the quantitative temperature comprehensive analysis early warning system further comprises a direct current power supply 8 and a PC10 which are arranged outside the probe, an external wiring hole 15 is formed in the end face of the upper cover 17, the direct current power supply 8 supplies power to the environment generating unit 3 and the microprocessor 9 through the external wiring hole 15, and the microprocessor 9 is in electric signal connection with the PC 10.
Preferably, the microprocessor is STM32F103RCT6, and has a signal acquisition ADC module integrated therein, which is not described in detail herein.
As shown in fig. 3, the contact 5-4 is cylindrical, an inner wiring hole is provided on the outer wall of the cylinder, and the pressure sensor 2 and the temperature detecting device 7 are respectively electrically connected with the microprocessor 9 through the inner wiring hole.
Further, the temperature changing device 4 is a semiconductor refrigerating sheet, the semiconductor refrigerating sheet and the pressure sensor 2 are of annular structures, the pressure sensor 2 is sleeved on the contact head 5-4, a plurality of force guide springs 14 are uniformly distributed on the outer side of the contact head 5-4 along the axial direction of the contact head 5-4, one end of each force guide spring 14 is fixedly connected with the pressure sensor 2, the other end of each force guide spring 14 is tightly attached to an infrared silicon lens, one or a plurality of heat guide springs 13 are arranged, one end of each heat guide spring is fixed on the semiconductor refrigerating sheet, the other end of each heat guide spring is tightly attached to the infrared silicon lens, and the heat guide springs are positioned on the inner side of the force guide springs 14; the temperature detection device 7 is an annular thermistor, the diameter of the annular thermistor is larger than that of the pressure sensor 2, the diameter of the semiconductor refrigerating piece is the same as that of the contact 5-4, and the annular thermistor, the semiconductor refrigerating piece, the pressure sensor 2 and the contact 5-4 are coaxial.
The invention changes the temperature of the infrared silicon lens by combining the heat conduction spring and the semiconductor refrigerating sheet. One end of the heat conduction spring is clung to one end face of the semiconductor refrigerating sheet, the other end of the heat conduction spring is clung to the infrared silicon lens, the heat conduction effect is achieved, and when the infrared silicon lens is stressed by external force, the compressible heat conduction spring moves within a certain range, so that the other surface of the semiconductor refrigerating sheet is clung to the radiator, and the temperature is kept near room temperature all the time; when the semiconductor refrigerating sheet is applied with forward voltage, the contact surface of the semiconductor refrigerating sheet and the heat conducting spring refrigerates, and the other surface of the semiconductor refrigerating sheet is heated; when reverse voltage is applied, the contact surface of the semiconductor refrigerating sheet and the heat conducting spring is heated, and the other surface of the semiconductor refrigerating sheet is refrigerated.
The invention senses the movement of the infrared silicon lens through the combination of the pressure sensor and the force guiding spring group. When the infrared silicon lens is displaced under the action of external force, the infrared silicon lens can press the guide force spring to deform to generate pressure and act on the pressure sensor. The pressure sensor 2 will detect the infrared silicon lens 11, and since one end of the pressure sensor is fixed on the contact head of the cold-heat exchange device 5, the pressure sensor will not displace when pressure exists.
Further, the PC10 is a computer or a PID controller, and is provided with an audible and visual alarm device. Audible and visual alarm devices are well known to those skilled in the art and will not be described in detail herein.
Further, the temperature rising and falling speed of the infrared silicon lens 1 is 1 ℃/s; the temperature changing device 4 is a semiconductor refrigerating sheet, the temperature changing device 4, the pressure sensor 2 and the cold-heat exchange device 5 are hollow structures, a light path is provided between the infrared silicon lens 11 and the infrared temperature sensor 1, and accurate measurement of the infrared temperature sensor 1 is facilitated.
A quantitative temperature comprehensive analysis early warning method comprises the following specific steps:
(1) The probe is set to a temperature changing mode through the PC10, the initial temperature of the test is set to 30-32 ℃, and then the initial temperature is transmitted to the microprocessor 9;
(2) After receiving the temperature changing instruction, the microprocessor 9 changes the temperature of the contact surface of the temperature changing device 4 and the heat conducting spring 13 through the temperature control relay 6, and then the temperature is conducted to the infrared silicon lens 11 through the heat conducting spring 13, so that the temperature of the infrared silicon lens 11 is changed within-5 ℃ to 50 ℃; the temperature of the infrared silicon lens 1 is monitored in real time through the temperature detection device 7, and the monitored temperature is transmitted to the microprocessor 9;
(3) The upper limit of the safe temperature is set to 44 ℃ through the PC10, the lower limit of the safe temperature is set to 10.8 ℃, the detected object is detected through the infrared silicon lens of the probe, the temperature of the detected object is detected through the infrared silicon lens 11 by the infrared temperature sensor 1, and the detected temperature is transmitted to the microprocessor 9; the microprocessor 9 transmits the data detected by the temperature detection device 7 and the infrared temperature sensor 1 to the PC10 for data storage and data analysis and profiling;
(4) When the temperature of the measured object reaches a threshold value, an audible and visual alarm device in the PC10 gives an early warning to remind the user of paying attention, and the duration is 30s; when the infrared temperature sensor 1 detects that the accumulated temperature of the measured object exceeds the warning temperature for more than 30s, the microprocessor 9 sends out an alarm signal and automatically changes the voltages at the two ends of the temperature changing device 4 to perform a cold and heat source re-heating mode, so that the temperature of the measured object returns to a safe temperature range of 30-32 ℃;
(5) If the infrared silicon lens 1 moves, the pressure signal is transmitted to the pressure sensor 2 through the force guiding spring 14, the pressure sensor 2 transmits the information of the detected movement of the infrared silicon lens 11 to the microprocessor 9, and the data detected by the microprocessor 9 is transmitted to the PC10 for data storage, data analysis and profiling.
Example 3
On the basis of the embodiment 1 or 2, the side wall of the upper cover 17 is provided with a bracket fixing hole 16; threads are provided in the bracket fixing hole 16. The bracket fixing hole 16 is connected with a bracket through threads, the bracket consists of a bracket seat and a bracket aluminum core supporting tube, one end of the bracket aluminum core supporting tube is fixed on the bracket seat, and the other end of the bracket aluminum core supporting tube is detachably connected with the bracket fixing hole 16 through threads.
When the device is used, the aluminum core support tube of the bracket is connected with the probe through the threads of the bracket fixing holes, and the probe is positioned at a proper position for detection by adjusting the height and the left and right positions of the aluminum core support tube of the bracket. The invention uses the bracket to liberate both hands during measurement, so that doctors can concentrate on the acquisition of measurement indexes. The stability of the system is improved, the change of the pressure sensor caused by operation is avoided, and the accuracy of test data is improved.
Example 4
Based on the embodiment 3, the probe is made of titanium alloy material; the infrared silicon lens (11) has a transmittance of more than 90% to infrared light and a heat conduction coefficient of 150; The accuracy of the infrared sensor is ensured. The heat conduction spring is made of copper material, and the heat conductivity is 410/>; The elastic coefficient/>, of the force guiding springIs 0.4The displacement of the spring is related to the pressure as/>Wherein/>For pressure acting on the pressure sensor,/>Is the elastic coefficient of the spring,/>Is the displacement of the spring.
Example 5
The invention relates to an application of a quantitative shallow feeling comprehensive analysis early warning system, which comprises the following steps: the object to be tested in this embodiment may be skin, or other items.
1. Skin testing is specifically described:
1. the specific test steps are as follows:
(1) The probe is set to a variable temperature mode by the PC10, the initial temperature of the test is set to 30-32 ℃ (the temperature is not cool and hot when the probe is contacted for a few seconds), and then the temperature is transmitted to the microprocessor 9;
(2) After receiving the temperature changing instruction, the microprocessor 9 changes the temperature of the contact surface of the temperature changing device 4 (semiconductor refrigerating sheet) and the heat conducting spring 13 through the temperature control relay 6, and then the temperature is conducted to the infrared silicon lens 11 through the heat conducting spring 13, so that the temperature of the infrared silicon lens 11 is changed within-5 ℃ to 50 ℃; the temperature of the infrared silicon lens 1 is monitored in real time through a temperature detection device 7 (thermistor), and the monitored temperature is transmitted to a microprocessor 9;
(3) Setting the upper limit of the skin safety temperature to 44 ℃ and the lower limit to 10.8 ℃ through the PC10, detecting the skin through the infrared silicon lens of the probe, detecting the skin temperature through the infrared silicon lens 11 by the infrared temperature sensor 1, and transmitting the detected temperature to the microprocessor 9; the microprocessor 9 transmits the data detected by the temperature detection device 7 and the infrared temperature sensor 1 to the PC10 for data storage and data analysis and profiling;
(4) When the skin temperature reaches a threshold value, an audible and visual alarm device in the PC10 gives an early warning to remind the user of paying attention, and the duration is 30s; when the infrared temperature sensor 1 detects that the accumulated temperature of the detected object exceeds the warning temperature for more than 30s, the microprocessor 9 sends out an alarm signal and automatically changes the voltages at the two ends of the temperature changing device 4 to perform a cold and heat source re-heating mode, so that the skin temperature is returned to a safer temperature range of 30-32 ℃; the temperature rising and falling speed of the infrared silicon lens is 1 ℃/s;
The sequence is that the cold threshold value is measured by an infrared temperature sensor, then the cold pain threshold value is measured, after 5 minutes, the initial temperature of the monitored skin is the same as that before the monitoring, and the measurement of the heat threshold value and the heat pain threshold value is carried out (considering that the peripheral feeling is not sensitive to the cold stimulus, the sensitivity to the cold feeling is reduced to the greatest extent after the process is used for reducing the heat stimulus, and in addition, the influence of the cold perception state to the heat perception state is avoided at proper intervals, thereby improving the measurement precision)
(5) When the invention is used, the control is carried out by a double control system (namely, the automatic control is carried out by a sensor, a microprocessor and other parts and the manual control by a mouse is adopted), when the cold, hot, cold pain and hot pain threshold values are measured, a patient clicks a button by using the mouse, and the accumulated temperature of skin, the heat source temperature and the heating (refrigerating) time when clicking the button are recorded. On the other hand, the pressure sensor attached to the probe can identify protective reactions (such as shrinkage reaction, when the pressure sensor detects the movement of the infrared silicon lens) caused by cold pain and hot pain, and the sensor and the microprocessor are used for signal conversion to record the accumulated skin temperature, the heat source temperature and the heating (refrigerating) time. (aiming at children, the personnel with disturbance of autonomous consciousness and the special diseases of the brain nerve conduction system, the mouse record can not necessarily represent the real state at the moment, and the pressure sensor is introduced to capture various indexes generating protective response at the moment, which is particularly critical for the measurement of cold pain and hot pain sense. The recording time is selected as the recording time before the recording time.
The invention quantitatively obtains the index capable of judging the self-protection capability of the skin, and based on the experimental principle of a hot plate, the accumulated temperature and time of the skin when the skin is heated by a constant-temperature heating source (a milder heating source can not generate obvious protective reaction when the skin is contacted with the constant-temperature heating source) or generates self-protection reaction (similar to a hands shrinkage reaction, and the pressure sensor can detect the movement of an infrared silicon lens). The accumulated skin temperature is monitored in real time through an infrared temperature sensor, an early warning system with the upper limit and the lower limit of the skin safety temperature set is established, and skin secondary damage caused by the detection process is prevented.
2. In the test, the invention can combine the nine-step method to quantitatively obtain the initial temperature of the skin and comprehensively judge the heat dissipation capacity of the skin or peripheral nerve vascular diseases, and the specific steps are as follows:
1) Dividing the detected skin part into 9 areas on average, measuring the skin temperature of the skin of the target area, recording the temperature of each area by using a PC (personal computer), repeatedly measuring each area, measuring 9 numerical values measured by the two areas, and automatically performing rank sum test by a microprocessor to judge whether the skin temperature is normal or not;
2) Measuring the skin temperature of the skin of the corresponding healthy area and recording the temperature of each area with a PC in the same way, wherein each area can be repeatedly measured;
The two steps are completed, the PC automatically performs rank sum test on 9 numerical values measured by the two areas recorded by the two steps, and if the statistical difference exists, the PC performs comprehensive judgment by combining other clinical indexes;
If the local skin temperature is high, the skin heat dissipation function is reduced (sweat gland function is reduced), or local skin is subjected to pathological changes such as inflammation; if the local skin temperature is low it may be suspected to be associated with peripheral vascular lesions and peripheral nerve dysfunction of its dominance.
And comprehensively analyzing the disease progress or the effectiveness of treatment by recording at different times and keeping skin temperature records.
3. After the microprocessor of the invention transmits the data to the PC, the PC stores the data to form an archive of a single patient and can be combined with a LOESS model to analyze the course change of the patient, and the obtained data is automatically combined with a rank test (rank sum test and kruscal willis test) to carry out statistical test.
The system of the invention can obtain the accumulated skin temperature when various thresholds are generated on the basis of improving the accuracy of the measured (cold, hot, cold pain and hot pain) thresholds. In addition, the temperature probe can be adjusted to be constant at 47+/-3 ℃ and 0+/-3 ℃, the time and the accumulated temperature of the skin required by protective reaction or thermal pain are measured, the index capable of judging the self-protective capability of the skin is obtained quantitatively, and the index can be combined with the measured (cold, hot, cold pain and thermal pain) threshold value result to carry out comprehensive analysis, so as to quantitatively judge and identify whether the peripheral superficial sensation (pain and temperature sensation) of the body is abnormal or not and whether the abnormal light and heavy are abnormal. In addition, due to the real-time temperature detection early warning system and the intelligent rewarming system, skin damage to a subject caused by detection can be avoided. The skin safety temperature can be preset when some thermal treatment or cold treatment (such as hip bath) is carried out on the crowd with the confirmed superficial peripheral paresthesia, the accumulated skin temperature is monitored in real time, and the safety threshold is reached, so that the skin safety of the crowd can be protected and pre-warned through alarming. The infrared silicon lens and the infrared temperature sensor can quantitatively measure the skin temperature of the skin at a specific part, and can be combined with sweat gland function detection to comprehensively judge the heat dissipation capacity of the skin. Therefore, the system plays an important role in diagnosis, identification, auxiliary treatment and long-term monitoring of the disease.
2. The quantitative shallow feeling comprehensive analysis early warning system is used as a heat source or a cold source and becomes auxiliary medical equipment for carrying out heat treatment or cold treatment: the invention sets the probe to a constant temperature mode through the PC, and the microprocessor controls the voltage applied to the two ends of the semiconductor refrigerating sheet to control the temperature of the temperature changing device after receiving the instruction so that the temperature of the infrared silicon lens is fixed at 47+/-3 ℃ or 0+/-3 ℃ for being used as a heat source or a cold source; can be used as auxiliary medical equipment in the process of thermal therapy or cold therapy, and can realize the skin safety protection of the crowd with hypoesthesia, dullness or disappearance of the periphery.
1) The crowd who carries out heat therapy or cold therapy detects the patient by fixing the probe above the skin when carrying out treatment;
2) The upper limit of the skin safety temperature is set to 44 ℃ and the lower limit is set to 10.8 ℃, so that the thermal therapy or the cold therapy is adopted, the early warning is carried out when the accumulated skin temperature exceeds the set warning temperature, the temperature is automatically changed into the rewarming mode after the duration time is more than 30s, and the skin temperature damage caused by the treatment is prevented.
If cold pain test is carried out, firstly, measuring the time and the accumulated temperature of skin for generating cold pain and generating protective reaction at the temperature of 0+/-3 ℃, fixing the temperature of the probe at 47+/-3 ℃ after the skin temperature is recovered to be normal, and recording the time and the accumulated temperature of skin for generating cold pain and generating protective reaction. When the accumulated skin temperature exceeds the set warning temperature, the early warning is carried out, and the temperature automatically changes into the rewarming mode after the duration time is more than 30s, so that the skin temperature damage caused by treatment is prevented.
3. The quantitative shallow feeling comprehensive analysis early warning system is used as an instrument for measuring nerve conduction: the animal nerve conduction measurement can be carried out in animal experiments, and because the animal does not have consciousness to record that the animal passes through the system, the time of a protection reaction (foot contraction reaction), the heat source temperature and the accumulated skin temperature are recorded through the pressure sensor, so that the animal peripheral nerve conduction condition is quantitatively analyzed.
4. The quantitative shallow feeling comprehensive analysis early warning system is used as an instrument for accurately measuring the melting point of a substance: the precise determination of the melting point of the substance is specifically: 1) The function is based on a temperature changing mode of the probe, and the temperature is detected in real time through the pressure sensor, the bracket and the infrared temperature sensor; 2) For substances (solid-liquid transition) where part changes state at a certain temperature; 3) Measuring the melting point (solid-liquid transition temperature) of the substance by a temperature change mode; 4) The probe is set in a temperature changing mode, the temperature is increased at the speed of 1 ℃ per second, and a bracket is used for enabling a substance to be in close contact with the probe, and a certain pressure value is obtained at the beginning; 5) The accumulated temperature of the measured object and the temperature of the heating source are monitored in real time along with the change of the temperature, the change of the pressure sensor is closely monitored, and when the detection value of the pressure sensor changes greatly, the surface temperature of the measured object corresponding to the time point is the melting point of the substance; 6) The mean and standard deviation were determined five times to define the melting point of the material.
5. The quantitative shallow feeling comprehensive analysis early warning system is used as an instrument for thermodynamic identification of material purity: thermodynamic identification of material purity is specifically: 1) Firstly, measuring the melting point of a standard substance A through the operation flow for precisely measuring the melting point of a substance; 2) Measuring the melting point of the substance to be identified by using the same flow; 3) If the melting point of the sample is different from that of the standard by more than 5%, a difference in the composition of the substances can be suspected and further analysis of the substance composition can be performed.
6. The quantitative shallow feeling comprehensive analysis early warning system is used as an instrument for quality identification of temperature sensitive substances and thermolabile materials: quality identification and protection of temperature sensitive or thermolabile materials (e.g. leather, foam, etc.) materials: 1) On the basis of accurately measuring the melting point of a substance, an automatic rewarming system is required to be additionally used; 2) Firstly, measuring the dangerous temperature (melting point) of a standard substance or material through an operation flow for accurately measuring the melting point of the substance; 3) Further performing purity or quality identification of such materials and materials by employing operations for thermodynamic identification of purity of the materials; 4) In the measuring process or due to other reasons, the material is in a local heating state, and the surface temperature of the material is monitored in real time, so that the material can be immediately and automatically started or converted into a rewarming mode in the range of dangerous temperature, the material is restored to a safe value range, and the protection of the specific material is realized.
It will be understood by those of ordinary skill in the art that the foregoing embodiments are specific examples of carrying out the invention and that various changes in form and details may be made therein without departing from the spirit and scope of the invention. The components and structures not specifically described in this embodiment are well known in the art and are not described in detail herein.
Claims (6)
1. The quantitative shallow feeling comprehensive analysis and early warning system is characterized in that: the probe comprises an upper cover (17), a cold and heat exchange device (5), a probe shell (12) and an infrared silicon lens (11), wherein one end of the cold and heat exchange device (5) is sleeved with the probe shell (12), the other end of the cold and heat exchange device is sleeved with the upper cover (17), and the infrared silicon lens (11) is arranged on the end face of the probe shell (12); the cold-heat exchange device (5) is a cylindrical heat dissipation shell (5-2) with a heat dissipation fin (5-1) at one end, a contact head (5-4) arranged along the axis direction of the cylinder is arranged in the cylindrical heat dissipation shell (5-2), an infrared temperature sensor (1) and a microprocessor (9) are arranged at one end of the contact head (5-4), and a pressure sensor (2) is arranged at the other end of the contact head; the probe shell (12) is cylindrical, a temperature detection device (7) is arranged in the probe shell, the temperature detection device (7) is annular and is clung to the infrared silicon lens (11), and the infrared silicon lens (11) is also connected with the temperature changing device (4) and the pressure sensor (2) through a heat conduction spring (13) and a force conduction spring (14) respectively; the temperature changing device (4) and the contact heads (5-4) are positioned on the same axis correspondingly, the temperature changing device (4) and the cold-heat exchange device form an environment generating unit (3), the environment generating unit (3) is electrically connected with the microprocessor (9) through the temperature control relay (6), and the infrared temperature sensor (1), the pressure sensor (2) and the temperature detection device (7) are respectively electrically connected with the microprocessor (9);
the probe is characterized by further comprising a direct current power supply (8) and a PC (10) which are arranged outside the probe, wherein an external wiring hole (15) is formed in the end face of the upper cover (17), the direct current power supply (8) supplies power to the environment generating unit (3) and the microprocessor (9) through the external wiring hole (15), and the microprocessor (9) is in electrical signal connection with the PC (10);
The contact head (5-4) is in a cylinder shape, an inner wiring hole is formed in the outer wall of the cylinder, and the pressure sensor (2) and the temperature detection device (7) are respectively and electrically connected with the microprocessor (9) through the inner wiring hole.
2. The quantitative shallow feeling integrated analysis pre-warning system according to claim 1, characterized in that: the temperature changing device (4) is a semiconductor refrigerating sheet, the semiconductor refrigerating sheet and the pressure sensor (2) are of annular structures, the pressure sensor (2) is sleeved on the contact head (5-4), a plurality of force guiding springs (14) are uniformly distributed on the outer side of the contact head (5-4) along the axial direction of the contact head (5-4), one end of each force guiding spring (14) is fixedly connected with the pressure sensor (2), the other end of each force guiding spring is tightly attached to the infrared silicon lens, one or more heat guiding springs (13) are arranged, one end of each heat guiding spring is fixed on the semiconductor refrigerating sheet, and the other end of each heat guiding spring is tightly attached to the infrared silicon lens and positioned on the inner side of each force guiding spring (14); the temperature detection device (7) is an annular thermistor, the diameter of the annular thermistor is larger than that of the pressure sensor (2), the diameter of the semiconductor refrigerating sheet is the same as that of the contact head (5-4), and the annular thermistor, the semiconductor refrigerating sheet, the pressure sensor (2) and the contact head (5-4) are coaxial.
3. The quantitative shallow feeling integrated analysis pre-warning system according to claim 1, characterized in that: the side wall of the upper cover (17) is provided with a bracket fixing hole (16); threads are arranged in the bracket fixing holes (16).
4. The quantitative shallow feeling analysis-by-synthesis early warning system according to claim 3, characterized in that: the support fixing hole (16) is connected with a support through threads, the support consists of a support seat and a support aluminum core supporting tube, one end of the support aluminum core supporting tube is fixed on the support seat, and the other end of the support aluminum core supporting tube is detachably connected with the support fixing hole (16) through threads.
5. The quantitative shallow feeling integrated analysis pre-warning system according to claim 1, characterized in that: the probe is made of titanium alloy material; the infrared silicon lens (11) has a transmittance of more than 90% to infrared light and a heat conduction coefficient of 150; The heat conduction spring is made of copper material, and the heat conductivity is 410/>; The elastic coefficient/>, of the force guiding springIs 0.4/>The displacement of the spring is related to the pressure as/>Wherein/>For pressure acting on the pressure sensor,/>Is the elastic coefficient of the spring,/>Is the displacement of the spring.
6. The quantitative shallow feeling integrated analysis pre-warning system according to claim 1, characterized in that: the temperature rising and falling speed of the infrared silicon lens (11) is 1 ℃/s; the temperature changing device (4) is a semiconductor refrigerating sheet, and the temperature changing device (4), the pressure sensor (2) and the cold-heat exchange device (5) are hollow structures and provide a light path between the infrared silicon lens (11) and the infrared temperature sensor (1).
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Citations (2)
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| CN2312450Y (en) * | 1997-07-18 | 1999-03-31 | 广州市新技术应用研究所 | Instrument for sensing and measuring skin temp. |
| CN109414198A (en) * | 2016-06-30 | 2019-03-01 | 欧普斯尼奥伊有限责任公司 | For characterizing the measuring system and method for tissue |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US8849379B2 (en) * | 2002-04-22 | 2014-09-30 | Geelux Holdings, Ltd. | Apparatus and method for measuring biologic parameters |
| US20090270757A1 (en) * | 2008-02-11 | 2009-10-29 | Miroslav Backonja | Thermal probe for quantitative sensory pain testing |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2312450Y (en) * | 1997-07-18 | 1999-03-31 | 广州市新技术应用研究所 | Instrument for sensing and measuring skin temp. |
| CN109414198A (en) * | 2016-06-30 | 2019-03-01 | 欧普斯尼奥伊有限责任公司 | For characterizing the measuring system and method for tissue |
Non-Patent Citations (1)
| Title |
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| 定量感觉测试在三叉神经区域应用的研究初探;顾鑫宇等;口腔生物医学;20150325(01);全文 * |
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