CN111388620A - Composition for tonifying qi, strengthening spleen, promoting circulation and helping digestion and preparation method and application thereof - Google Patents

Composition for tonifying qi, strengthening spleen, promoting circulation and helping digestion and preparation method and application thereof Download PDF

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Publication number
CN111388620A
CN111388620A CN202010311796.8A CN202010311796A CN111388620A CN 111388620 A CN111388620 A CN 111388620A CN 202010311796 A CN202010311796 A CN 202010311796A CN 111388620 A CN111388620 A CN 111388620A
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parts
composition
tonifying
raw materials
spleen
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朱卫刚
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Shijiazhuang Yunning Health Management Co ltd
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Shijiazhuang Yunning Health Management Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732—Chaenomeles, e.g. flowering quince
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9064—Amomum, e.g. round cardamom
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention relates to the technical field of medicinal and edible products, in particular to a composition for tonifying qi, invigorating spleen, assisting transportation and helping digestion and a preparation method and application thereof. The composition comprises the following raw materials: the composition has the effects of tonifying qi and strengthening spleen, assisting transportation and digestion, improving anorexia, food retention and combining constipation or diarrhea and other symptoms, and can be used for auxiliary treatment and conditioning of intestinal lymphadenitis.

Description

Composition for tonifying qi, strengthening spleen, promoting circulation and helping digestion and preparation method and application thereof
Technical Field
The invention relates to the technical field of medicinal and edible products, in particular to a composition for tonifying qi, invigorating spleen, assisting transportation and helping digestion and a preparation method and application thereof.
Background
With the increasing modern living standard, food sources are rich, and nondigestible foods such as high calorie and high fat enter daily diet more and more due to delicacy, so that the burden of spleen and stomach is gradually increased after long-term accumulation, and the symptoms of food accumulation, anorexia, dyspepsia and the like are caused. Food accumulation is more common for children with weakness of spleen and stomach, food preference and eating habits, the children lose appetite and reduce food intake after food accumulation, cough, fever, vomiting, abdominal distension, abdominal pain, diarrhea or constipation can be further caused, the intake of necessary nutrition for the growth of the children is interfered, and malnutrition can be caused, so that the growth and development of the children are influenced.
However, for adults and children with weakness of the spleen and the stomach, if the traditional Chinese medicine is directly used after the symptoms appear, certain side effects may exist, and the traditional Chinese medicine product is usually poor in taste and poor in compliance of children with the traditional Chinese medicine. Food therapy is safe, but most of the food therapy takes a slow effect and needs a long time to improve the symptoms.
Disclosure of Invention
The invention provides a composition for tonifying qi, strengthening spleen, assisting in transportation and helping to digest, aiming at the technical problems of certain side effects of traditional Chinese medicines and slow effect taking of food therapy.
The invention also provides a preparation method of the composition for tonifying qi, invigorating spleen, promoting circulation and helping digestion.
In order to achieve the purpose of the invention, the embodiment of the invention adopts the following technical scheme:
the composition for tonifying qi, strengthening spleen, promoting movement and helping digestion comprises the following raw materials in parts by weight: 9-17 parts of codonopsis pilosula, 8-13 parts of bighead atractylodes rhizome, 8-13 parts of poria cocos, 8-13 parts of lotus seed, 8-13 parts of Chinese yam, 8-13 parts of endothelium corneum gigeriae galli, 8-13 parts of pawpaw, 8-13 parts of dried orange peel, 5-11 parts of fructus amomi and 3-7 parts of honey-fried licorice root.
The codonopsis pilosula is sweet in taste and neutral in nature, and has the effects of tonifying spleen and lung channels, tonifying middle-jiao and Qi, quenching thirst, tonifying spleen and lung, nourishing blood and promoting the production of body fluid.
Bighead atractylodes rhizome is bitter and sweet in taste and warm in nature, enters spleen and stomach channels, invigorates qi and strengthens spleen, and eliminates dampness and promotes diuresis.
Poria has sweet and light taste and neutral nature, and has effects of invigorating heart, spleen and kidney channels, promoting diuresis, eliminating dampness, invigorating spleen, and tranquilizing mind.
Lotus seed is sweet and astringent in flavor, neutral in nature, and has the effects of tonifying the spleen, stopping diarrhea, nourishing the heart and soothing the nerves.
Yam is sweet in flavor and neutral in nature, and has the effects of invigorating qi, nourishing yin, tonifying spleen and lung, and regulating the function of spleen and kidney.
The endothelium corneum Gigeriae Galli is sweet in flavor and neutral in nature, enters spleen, stomach, small intestine and bladder channels, promotes digestion and invigorates spleen, and is especially suitable for people with food stagnation and spleen deficiency.
Pawpaw is sour in taste and warm in nature, enters liver and spleen channels, relaxes tendons and activates collaterals, and dissolves dampness to harmonize stomach.
The dried orange peel is pungent and bitter in flavor and warm in nature, enters spleen, stomach and lung channels, regulates qi and harmonizes the middle, eliminates dampness and phlegm, promotes diuresis and relieves constipation.
Sha ren is pungent in flavor and warm in nature, enters spleen and stomach meridians, and also acts as a dampness-resolving, qi-moving and middle-warming herb.
Prepared licorice root, radix Glycyrrhizae Praeparata, sweet in taste, neutral in nature, enters stomach, heart, lung and spleen channels, and has the effects of tonifying spleen and stomach, and tonifying qi and restoring pulse.
In the composition provided by the invention, the codonopsis pilosula is a monarch drug for tonifying spleen and stomach, and is sweet, warm and qi-tonifying.
The bitter and warm property of the atractylodes macrocephala is used for strengthening spleen and warming yang, assisting transportation and drying dampness and assisting the codonopsis pilosula in tonifying spleen qi; poria, because of its sweet and bland nature, it can drain damp-turbidity and is combined with Bai Zhu to tonify blood and relieve stagnation. The rhizoma atractylodis macrocephalae and the tuckahoe are used as ministerial drugs.
The lotus seeds can tonify qi of spleen, stomach and heart, tonify qi, invigorate spleen, activate spleen, stimulate appetite and have the effect of relieving diarrhea with astringents; the Chinese yam has the functions of tonifying spleen, lung and stomach qi, can be used for treating spleen deficiency and nourishing spleen yin, is used for treating spleen qi deficiency, malnutrition, poor appetite and loose stool, and has good effect when being used together with the lotus seeds; the pawpaw has the effects of eliminating dampness and relieving dyspepsia, is suitable for infantile dyspepsia and anorexia, and can be used together with endothelium corneum gigeriae galli to strengthen the effects of relieving dyspepsia and promoting appetite; pericarpium Citri Reticulatae is warm but not dry, and can move qi and regulate middle energizer, and is good at moving spleen and stomach qi, centering and centering on the diaphragm, so as to strengthen the transportation and transformation of the recipe; sha ren warms the middle energizer to resolve dampness, and assists the herbs of this recipe to move qi and strengthen the transportation and transformation. Lotus seed, yam, chicken's gizzard-membrane, pawpaw, dried orange peel and amomum fruit are used as adjuvant drugs in the recipe.
Prepared licorice root, radix Glycyrrhizae Praeparata has the effect of tonifying the spleen and stomach, and can regulate the property of the drug, acting as a guiding drug in the recipe.
The raw materials with homology of medicine and food act synergistically in the composition, have the effects of tonifying qi and strengthening spleen, helping transportation and digestion, improving anorexia and food retention, and combining constipation or diarrhea symptoms, and can be used for auxiliary treatment and conditioning of intestinal lymphadenitis.
Preferably, the composition comprises the following raw materials in parts by weight: 10-15 parts of codonopsis pilosula, 10-12 parts of bighead atractylodes rhizome, 10-12 parts of poria cocos, 10-12 parts of lotus seeds, 10-12 parts of Chinese yam, 10-12 parts of endothelium corneum gigeriae galli, 10-12 parts of pawpaw, 10-12 parts of dried orange peel, 6-10 parts of fructus amomi and 4-6 parts of honey-fried licorice root.
Preferably, the composition comprises the following raw materials in parts by weight: 12 to 14 parts of codonopsis pilosula, 10.5 to 11.5 parts of bighead atractylodes rhizome, 10.5 to 11.5 parts of poria cocos, 10.5 to 11.5 parts of lotus seed, 10.5 to 11.5 parts of Chinese yam, 10.5 to 11.5 parts of chicken's gizzard-membrane, 10.5 to 11.5 parts of pawpaw, 10.5 to 11.5 parts of dried orange peel, 7 to 9 parts of fructus amomi and 4 to 6 parts of honey-fried licorice root.
Preferably, the composition comprises the following raw materials in parts by weight: 13 parts of codonopsis pilosula, 11 parts of bighead atractylodes rhizome, 11 parts of poria cocos, 11 parts of lotus seed, 11 parts of Chinese yam, 11 parts of endothelium corneum gigeriae galli, 11 parts of pawpaw, 11 parts of dried orange peel, 8 parts of fructus amomi and 5 parts of honey-fried licorice root.
In the practical use of the traditional Chinese medicine, 1g of the traditional Chinese medicine is used as each dose, and 1 dose is used every 1-2 days according to the state of illness.
Preferably, the codonopsis pilosula is replaced by heterophylly falsestarwort root, and the lotus seed and the Chinese yam are replaced by gordon euryale seed. The replaced composition is more suitable for children under 12 years old.
The embodiment of the invention also provides a preparation method of the composition for tonifying qi, invigorating spleen, assisting transportation and helping digestion, which comprises the steps of respectively crushing the raw materials in the composition, weighing the raw material powder according to the proportion, and mixing to obtain the composition.
The embodiment of the invention also provides a preparation method of another composition for tonifying qi, invigorating spleen, promoting circulation and helping digestion, which comprises the following steps: weighing the raw materials according to the raw material proportion in the composition, mixing, crushing, decocting with water, and collecting the obtained extract. The extractive solution can be concentrated according to actual requirement, and further dried.
The preparation method is simple to operate, and can be used for small-batch production and large-production-scale batch production. The extracts obtained by the two preparation methods can be further processed into oral dosage forms such as powder, tablet, capsule, etc., and the extract can be further processed into oral dosage forms such as oral liquid, syrup, etc.
Preferably, the water decoction extraction method is decocting for 1-3 times, and each time lasts for 20-40 min.
Also provided in the embodiments of the present invention is the use of the above composition in the manufacture of a product for conditioning the symptoms of anorexia bulimia. The composition provided by the invention has a remarkable effect on conditioning food retention and anorexia symptoms, and the symptoms can disappear in 2-10 days.
The embodiment of the invention also provides application of the composition in preparing a product for conditioning anorexia bulimia combined constipation or anorexia bulimia combined diarrhea. The composition provided by the invention can be used for conditioning symptoms of anorexia and constipation, so that the symptoms can disappear in about three weeks to one month, and the symptoms can be cured in about five weeks to one month and a half.
The embodiment of the invention also provides application of the composition in preparing a product for adjuvant therapy and/or conditioning of the intestinal lymphadenitis. The obtained product is used for adjuvant treatment and/or conditioning of intestinal lymphadenitis, and can relieve symptoms of abdominal pain, nausea, emesis, etc. caused by intestinal lymphadenitis, reduce pain of patients, and promote recovery of organism.
The product for conditioning the symptoms of the food retention and the anorexia, the product for conditioning the constipation complicated by the food retention and the anorexia, the product for conditioning the diarrhea complicated by the food retention and the anorexia and the product for conditioning the intestinal lymphadenitis comprise foods, health-care foods or medicines, and the product for auxiliary treatment of the intestinal lymphadenitis comprises the health-care foods or the medicines. The food category comprises powder paste, biscuit, honey paste and the like; the dosage forms of the health food and the medicine comprise chewable tablets, dispersible tablets, powder, granules, capsules and the like, and when the composition prepared by water decoction extraction is prepared into the product, the dosage forms of the product also comprise oral liquid, honey paste, syrup and the like. The application does not limit the types of food and the dosage forms of health food and medicines, and the food and the medicines can be selected by the skilled in the art according to the needs and prepared by the conventional method.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Example 1
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 13g of codonopsis pilosula, 11g of bighead atractylodes rhizome, 11g of poria cocos, 11g of lotus seed, 11g of Chinese yam, 11g of endothelium corneum gigeriae galli, 11g of pawpaw, 11g of dried orange peel, 8g of fructus amomi and 5g of honey-fried licorice root.
The preparation method comprises the following steps: respectively pulverizing the raw materials to particle size of less than 0.1mm, weighing the raw material powders according to the above ratio, and mixing to obtain the final product.
Example 2
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 13g of codonopsis pilosula, 11g of bighead atractylodes rhizome, 11g of poria cocos, 11g of lotus seed, 11g of Chinese yam, 11g of endothelium corneum gigeriae galli, 11g of pawpaw, 11g of dried orange peel, 8g of fructus amomi and 5g of honey-fried licorice root.
The preparation method comprises the following steps: weighing the above materials, mixing, crushing, decocting with water for 2 times (40 min each time), and collecting the obtained extractive solution.
Example 3
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 12g of codonopsis pilosula, 10.5g of bighead atractylodes rhizome, 10.5g of poria cocos, 10.5g of lotus seed, 10.5g of Chinese yam, 10.5g of endothelium corneum gigeriae galli, 10.5g of pawpaw, 10.5g of dried orange peel, 7g of fructus amomi and 4g of honey-fried licorice root.
The preparation method comprises the following steps: respectively pulverizing the raw materials to particle size of less than 0.1mm, weighing the raw material powders according to the above ratio, and mixing to obtain the final product.
Example 4
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 14g of codonopsis pilosula, 11.5g of bighead atractylodes rhizome, 11.5g of poria cocos, 11.5g of lotus seed, 11.5g of Chinese yam, 11.5g of endothelium corneum gigeriae galli, 11.5g of pawpaw, 11.5g of dried orange peel, 9g of fructus amomi and 6g of honey-fried licorice root.
The preparation method comprises the following steps: weighing the above materials, mixing, crushing, decocting in water for 3 times, each for 20min, collecting the obtained extractive solution, concentrating, and drying.
Example 5
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 10g of codonopsis pilosula, 10g of bighead atractylodes rhizome, 10g of poria cocos, 10g of lotus seed, 10g of Chinese yam, 10g of endothelium corneum gigeriae galli, 10g of pawpaw, 10g of dried orange peel, 6g of fructus amomi and 4g of honey-fried licorice root.
The preparation method comprises the following steps: weighing the above materials, mixing, crushing, decocting with water for 2 times (40 min each time), collecting the extractive solution, concentrating, and drying.
Example 6
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 15g of codonopsis pilosula, 12g of bighead atractylodes rhizome, 12g of poria cocos, 12g of lotus seed, 12g of Chinese yam, 12g of endothelium corneum gigeriae galli, 12g of pawpaw, 12g of dried orange peel, 10g of fructus amomi and 6g of honey-fried licorice root.
The preparation method comprises the following steps: respectively pulverizing the raw materials to particle size of less than 0.1mm, weighing the raw material powders according to the above ratio, and mixing to obtain the final product.
Example 7
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 13g of radix pseudostellariae, 11g of bighead atractylodes rhizome, 11g of poria cocos, 22g of gordon euryale seed, 11g of endothelium corneum gigeriae galli, 11g of pawpaw, 11g of dried orange peel, 8g of fructus amomi and 5g of honey-fried licorice root.
The preparation method comprises the following steps: respectively pulverizing the raw materials to particle size of less than 0.1mm, weighing the raw material powders according to the above ratio, and mixing to obtain the final product.
Example 8
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 13g of radix pseudostellariae, 11g of bighead atractylodes rhizome, 11g of poria cocos, 22g of gordon euryale seed, 11g of endothelium corneum gigeriae galli, 11g of pawpaw, 11g of dried orange peel, 8g of fructus amomi and 5g of honey-fried licorice root.
The preparation method comprises the following steps: weighing the above materials, mixing, crushing, decocting with water for 3 times, each for 20min, and collecting the obtained extractive solution.
Example 9
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 12g of radix pseudostellariae, 10.5g of bighead atractylodes rhizome, 10.5g of poria cocos, 21g of gordon euryale seed, 10.5g of endothelium corneum gigeriae galli, 10.5g of pawpaw, 10.5g of dried orange peel, 7g of fructus amomi and 4g of honey-fried licorice root.
The preparation method comprises the following steps: weighing the above materials, mixing, crushing, decocting with water for 1 time for 40min, collecting the obtained extractive solution, and concentrating.
Example 10
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 14g of radix pseudostellariae, 11.5g of bighead atractylodes rhizome, 11.5g of poria cocos, 23g of gordon euryale seed, 11.5g of endothelium corneum gigeriae galli, 11.5g of pawpaw, 11.5g of dried orange peel, 9g of fructus amomi and 6g of honey-fried licorice root.
The preparation method comprises the following steps: respectively pulverizing the raw materials to particle size of less than 0.1mm, weighing the raw material powders according to the above ratio, and mixing to obtain the final product.
Example 11
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 10g of radix pseudostellariae, 10g of bighead atractylodes rhizome, 10g of poria cocos, 20g of gordon euryale seed, 10g of endothelium corneum gigeriae galli, 10g of pawpaw, 10g of dried orange peel, 6g of fructus amomi and 4g of honey-fried licorice root.
The preparation method comprises the following steps: respectively pulverizing the raw materials to particle size of less than 0.1mm, weighing the raw material powders according to the above ratio, and mixing to obtain the final product.
Example 12
The embodiment of the invention provides a composition for tonifying qi, invigorating spleen, promoting movement and helping digestion, and each preparation comprises the following raw materials: 15g of radix pseudostellariae, 12g of bighead atractylodes rhizome, 12g of poria cocos, 24g of gordon euryale seed, 12g of endothelium corneum gigeriae galli, 12g of pawpaw, 12g of dried orange peel, 10g of fructus amomi and 6g of honey-fried licorice root.
The preparation method comprises the following steps: weighing the above materials, mixing, crushing, decocting with water for 30min for 2 times, collecting the extractive solution, concentrating, and drying.
Example 13
The embodiment of the invention provides an oral liquid for conditioning food retention and anorexia symptoms, which is prepared by concentrating, flavoring, sterilizing and filling the composition obtained in the embodiment 2, is suitable for people with food retention and anorexia in all ages above 1 year, and is particularly suitable for people above 12 years.
Example 14
The embodiment of the invention provides a powder paste for conditioning food retention and anorexia symptoms, which is prepared by mixing the composition obtained in the embodiment 7 with a flavoring agent, and is suitable for people with food retention and anorexia in all ages of over 1 year, especially for people under 12 years.
Example 15
The embodiment of the invention provides a dispersible tablet for conditioning food retention and anorexia combined constipation symptoms, which is prepared by mixing and compressing the composition obtained in the embodiment 1, an excipient, a disintegrant and a flavoring agent. Is suitable for people of 1 year or more, especially people of 12 years or more.
Example 16
The embodiment of the invention provides honey paste for conditioning food retention, anorexia and constipation symptoms, which is prepared by further concentrating the composition obtained in the embodiment 9 and adding honey to prepare thick paste. Is suitable for people of 2 years old or older with food retention, anorexia and constipation, especially people of 12 years old or younger.
Example 17
The embodiment of the invention provides a capsule for conditioning symptoms of food retention, anorexia and diarrhea, which is prepared by mixing the composition obtained in the embodiment 3, a filling agent and a flow aid and then filling the mixture into a capsule. Is suitable for people of 1 year old or older with food retention, anorexia and diarrhea symptoms, especially for people of 12 years old or older.
Example 18
The embodiment of the invention provides an oral liquid for conditioning food retention, anorexia and diarrhea symptoms, which is prepared by concentrating, flavoring, sterilizing and filling the composition obtained in the embodiment 8, is suitable for people of 1 year old or more and all ages with food retention, anorexia and diarrhea symptoms, and is particularly suitable for people of 12 years old or less.
Example 19
The embodiment of the invention provides a granule for adjuvant therapy of intestinal lymphadenitis, which is prepared by mixing and granulating the composition obtained in the embodiment 4, a filling agent and an adhesive, adding a glidant, uniformly mixing and subpackaging. Is suitable for adjuvant treatment of intestinal lymphadenitis patients of 1 year or more, especially suitable for people of 12 years or more.
Example 20
The embodiment of the invention provides powder for conditioning and treating intestinal lymphadenitis, which is prepared by mixing the composition obtained in the embodiment 10, a flocculating agent and a flavoring agent and subpackaging. Is suitable for daily conditioning of patients with intestinal lymphadenitis of 1 year or more, especially patients of 12 years or less.
Effect example 1
The effect example provides the using effect of the composition for tonifying qi, strengthening spleen, promoting circulation and helping digestion in the aspects of food retention and anorexia.
Counting objects: a total of 440 children (statistical subjects of each symptom were randomly selected from among children of similar ages) were administered with the compositions obtained in examples 1, 2, 7, and 8 from 2019 for 1 month to 2019 for 12 months, and each of the children was administered with 1 dose of the composition obtained in the corresponding example per day.
The time taken from the day of administration to the disappearance of each symptom was counted for each person by the follow-up results, and the results are shown in table 1.
TABLE 1 therapeutic effect of the composition of the present invention on anorexia
Figure BDA0002458127480000091
The average time is the sum of the symptom disappearance times per case divided by cases.
As can be seen from the results in table 1, the examples of the present invention have excellent conditioning effects on people with anorexia and combined constipation or diarrhea.
Effect example 2
The effect example provides the using effect of the composition for tonifying qi, strengthening spleen, promoting circulation and helping digestion in the aspect of adjuvant therapy and conditioning mesenteric lymphadenitis.
Counting objects: a total of 240 children (statistical subjects of each symptom randomly selected from among children of similar ages) were taken from the compositions obtained in examples 1, 2, 7, and 8 for 2019, 1 month to 2019, 12 months, and each of the children was taken with 1 dose of the composition obtained in the corresponding example each day.
The time taken from the day of administration to the disappearance of each symptom was counted for each person by the follow-up results, and the results are shown in table 2.
TABLE 2 Effect of the compositions of the present invention for the adjuvant treatment and Conditioning of mesenteric lymphoitis
Figure BDA0002458127480000101
The average time is the sum of the symptom disappearance times per case divided by cases.
As can be seen from the results in Table 2, the examples of the present invention have good adjuvant therapy and opsonization for mesenteric lymphadenitis.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents or improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (10)

1. The composition for tonifying qi, strengthening spleen, promoting movement and helping digestion is characterized by comprising the following raw materials in parts by weight: 9-17 parts of codonopsis pilosula, 8-13 parts of bighead atractylodes rhizome, 8-13 parts of poria cocos, 8-13 parts of lotus seed, 8-13 parts of Chinese yam, 8-13 parts of endothelium corneum gigeriae galli, 8-13 parts of pawpaw, 8-13 parts of dried orange peel, 5-11 parts of fructus amomi and 3-7 parts of honey-fried licorice root.
2. The composition for tonifying qi, invigorating spleen, promoting circulation and helping digestion as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight: 10-15 parts of codonopsis pilosula, 10-12 parts of bighead atractylodes rhizome, 10-12 parts of poria cocos, 10-12 parts of lotus seeds, 10-12 parts of Chinese yam, 10-12 parts of endothelium corneum gigeriae galli, 10-12 parts of pawpaw, 10-12 parts of dried orange peel, 6-10 parts of fructus amomi and 4-6 parts of honey-fried licorice root.
3. The composition for tonifying qi, invigorating spleen, promoting circulation and helping digestion as claimed in claim 2, which is characterized by comprising the following raw materials in parts by weight: 12 to 14 parts of codonopsis pilosula, 10.5 to 11.5 parts of bighead atractylodes rhizome, 10.5 to 11.5 parts of poria cocos, 10.5 to 11.5 parts of lotus seed, 10.5 to 11.5 parts of Chinese yam, 10.5 to 11.5 parts of chicken's gizzard-membrane, 10.5 to 11.5 parts of pawpaw, 10.5 to 11.5 parts of dried orange peel, 7 to 9 parts of fructus amomi and 4 to 6 parts of honey-fried licorice root.
4. The composition for tonifying qi, invigorating spleen, promoting circulation and helping digestion according to claim 3, which is characterized by comprising the following raw materials in parts by weight: 13 parts of codonopsis pilosula, 11 parts of bighead atractylodes rhizome, 11 parts of poria cocos, 11 parts of lotus seed, 11 parts of Chinese yam, 11 parts of endothelium corneum gigeriae galli, 11 parts of pawpaw, 11 parts of dried orange peel, 8 parts of fructus amomi and 5 parts of honey-fried licorice root.
5. The composition for tonifying qi, invigorating spleen, assisting transportation and helping digestion as claimed in any one of claims 1 to 4, wherein the codonopsis pilosula is replaced by radix pseudostellariae, and the lotus seed and the Chinese yam are replaced by gordon euryale seed.
6. A preparation method of a composition for tonifying qi, invigorating spleen, promoting circulation and helping digestion is characterized in that raw materials in the composition of any one of claims 1-5 are respectively crushed, and then are weighed according to a proportion and mixed to obtain the composition; or
Weighing the raw materials according to the mixture ratio of the raw materials in the composition of any one of claims 1 to 5, mixing, crushing, decocting with water, and collecting the obtained extract.
7. The preparation method of the composition for tonifying qi, invigorating spleen, promoting circulation and helping digestion according to claim 6, wherein the water decoction extraction method is decocting for 1-3 times, 20-40 min each time.
8. Use of a composition according to any one of claims 1 to 5 in the manufacture of a product for the management of anorexia bulimia.
9. Use of a composition according to any one of claims 1 to 5 in the manufacture of a product for conditioning anorexia bulimia combined constipation or anorexia bulimia combined diarrhea.
10. Use of a composition according to any one of claims 1 to 5 for the preparation of a product for the adjunctive treatment and/or conditioning of intestinal lymphadenitis.
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CN112438396A (en) * 2020-11-18 2021-03-05 海安市弘华生物科技有限公司 Food additive and preparation method thereof
CN115530306A (en) * 2022-10-13 2022-12-30 广东好味鲜菜品与营养研究所 Radix pseudostellariae-containing bubble beverage capable of strengthening spleen and enhancing immunity and production process thereof
CN115553418A (en) * 2022-09-29 2023-01-03 泸州肥儿粉股份有限公司 Complementary food for conditioning diarrhea and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN112438396A (en) * 2020-11-18 2021-03-05 海安市弘华生物科技有限公司 Food additive and preparation method thereof
CN115553418A (en) * 2022-09-29 2023-01-03 泸州肥儿粉股份有限公司 Complementary food for conditioning diarrhea and preparation method thereof
CN115530306A (en) * 2022-10-13 2022-12-30 广东好味鲜菜品与营养研究所 Radix pseudostellariae-containing bubble beverage capable of strengthening spleen and enhancing immunity and production process thereof

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Application publication date: 20200710