CN111358892A - Traditional Chinese medicine composition for treating novel coronavirus pneumonia in early and middle stages and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating novel coronavirus pneumonia in early and middle stages and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating novel coronary virus pneumonia in junior-middle period and a preparation method thereof, the traditional Chinese medicine composition adopts traditional Chinese medicines of ephedra, almond, gypsum, rhizoma anemarrhenae, bletilla striata, scutellaria baicalensis and raw liquorice as raw materials, the ephedra and the almond are good for the effect of monarch, and have the effects of relieving cough and asthma and eliminating phlegm, the gypsum and the rhizoma anemarrhenae are ministerial medicines and have the effects of clearing heat and relieving cough and asthma, the bletilla striata and the scutellaria baicalensis are used as adjuvant medicines and have the effects of clearing heat and removing toxicity and astringing lung, the raw liquorice is used as a guiding medicine and guiding the medicine to channel, and has the effects of relieving cough and asthma. The traditional Chinese medicine composition can be used as a novel medicine for treating the early and middle stage coronary viral pneumonia.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating novel coronavirus pneumonia in early and middle stages and a preparation method thereof.
Background
The novel coronavirus pneumonia is called new coronavirus pneumonia for short, and the world health organization is named as 2019 coronavirus disease, and the new coronavirus pneumonia refers to pneumonia caused by 2019 new coronavirus infection. The clinical manifestations of patients with pneumonia infected by the novel coronavirus are: general aching and soft pain, cough and asthma, fever, headache, little or no sweat, individual abdominal pain, diarrhea, and incubation period as long as 7-15 days. The popular characteristics are as follows: sudden violence, strong infectivity, fast epidemic speed and high death rate. The precautionary measures are as follows: early prevention, early discovery, early isolation and early treatment. Pathological changes are as follows: diffuse intrapulmonary infection, congestion, edema, damp pathogen producing phlegm. High-hair people: the prevalence rate of the middle-aged and the elderly is high. The infection route is as follows: respiratory tract.
For the new type of coronavirus pneumonia, no specific medicine is available for treating the disease at present.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a traditional Chinese medicine composition for early and middle stage novel coronary virus pneumonia and a preparation method thereof.
The technical scheme adopted by the invention is as follows:
a traditional Chinese medicine composition for treating novel coronavirus pneumonia in early and middle stages comprises the following raw material components: 6-12 parts of ephedra, 10-14 parts of almond, 15-25 parts of gypsum, 10-14 parts of rhizoma anemarrhenae, 12-18 parts of bletilla striata, 16-20 parts of scutellaria baicalensis and 6-12 parts of raw liquorice.
Further preferably, the traditional Chinese medicine composition for treating the novel coronavirus pneumonia in the early and middle stages comprises the following raw material components: 9 parts of ephedra, 12 parts of almond, 20 parts of gypsum, 12 parts of rhizoma anemarrhenae, 15 parts of bletilla striata, 18 parts of scutellaria baicalensis and 9 parts of raw liquorice.
The preparation method of the traditional Chinese medicine composition for the novel early-middle stage coronary viral pneumonia comprises the following specific steps:
(1) the preparation method comprises the following steps of taking the raw materials according to the weight parts, drying and crushing the raw materials respectively, and mixing the raw materials uniformly to obtain a mixed material;
(2) adding water into the mixed materials for decoction, and filtering to obtain a decoction liquid, thereby obtaining the traditional Chinese medicine composition for treating the novel coronavirus pneumonia in the early and middle stages.
In the step (1), the drying temperature is 80-120 ℃, and the drying time is 1-3 h.
The temperature for carrying out the drying is 100 ℃, and the time for carrying out the drying is 2 hours.
In the step (1), after the crushing, the particle size of the mixed material is 180-220 meshes.
In the step (1), after the mixture is crushed, the particle size of the mixture is 200 meshes.
In the step (2), during the decoction, the mass of the added water is 2-8 times of the mass of the mixed materials.
In the step (2), the decoction is carried out for 0.5-2 h.
In the step (2), the decoction is repeated twice, the decoction dregs obtained by the first decoction are added with water for the second decoction, the filtration is carried out, the decoction dregs are discarded, and the decoction liquids obtained by the two decoctions are mixed, so that the traditional Chinese medicine composition for treating the novel coronavirus pneumonia in the early and middle stages is obtained.
In order to facilitate understanding of the present invention, the raw materials and the drug effects of the present invention will be further described below.
Ma Huang is pungent, slightly bitter and warm in nature. Induce sweating and dispel cold, ventilate lung and relieve dyspnea, induce diuresis to alleviate edema. Can be used for treating common cold due to wind-cold, chest distress, cough, and edema; bronchial asthma. Honey Chinese ephedra can moisten lung and relieve cough. It is often indicated for exterior syndrome, asthma and cough.
Apricot kernel, bitter in taste, warm in nature and toxic. Dispel phlegm and relieve cough, relieve dyspnea, moisten intestines. It is indicated for cough due to exogenous pathogenic factor, dyspnea, throat impediment, constipation due to intestinal dryness.
Gypsum, Gypsum Fibrosum, sweet and pungent in flavor, cold in nature. Clear heat and purge fire, relieve restlessness and quench thirst. Can be used for treating fever due to exogenous pathogens, hyperpyrexia, polydipsia, cough and asthma due to lung heat, excessive stomach fire, headache, and toothache.
Zhi mu is bitter and sweet in flavor and cold in nature. Clear heat and purge fire, promote fluid production and moisten dryness. Can be used for treating exogenous febrile disease, hyperpyrexia with polydipsia, lung heat with cough, hectic fever due to yin-deficiency, diabetes due to internal heat, and constipation due to intestinal dryness.
Bletilla striata, bitter, sweet, astringent in taste, slightly cold in nature. Astringe to stop bleeding, resolve swelling and promote tissue regeneration. Can be used for treating hemoptysis, hematemesis, traumatic hemorrhage, pyocutaneous disease, toxic swelling, and chapped skin; pulmonary tuberculosis hemoptysis, ulcer hemorrhage.
Baikal skullcap root, radix Scutellariae is bitter in taste and cold in nature. Clear heat and dry dampness, purge fire and remove toxicity, stop bleeding, prevent abortion. Can be used for treating chest distress, nausea, damp-heat, dysentery, jaundice, cough due to lung heat, hyperpyrexia, polydipsia, hematemesis, carbuncle, swelling, sore, and threatened abortion.
Raw Licorice root, radix Glycyrrhizae is sweet in flavor and neutral in nature. Invigorating spleen and replenishing qi, clearing away heat and toxic material, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the drugs. Can be used for treating weakness of spleen and stomach, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limb spasm, pain, carbuncle, swelling, sore, and drug toxicity and strong nature.
The traditional Chinese medicine composition for the early and middle stage novel coronary virus pneumonia adopts the traditional Chinese medicines of ephedra, almond, gypsum, rhizoma anemarrhenae, bletilla striata, scutellaria baicalensis and raw liquorice as raw materials, the ephedra and the almond are good for monarch, have the effects of relieving cough and asthma and eliminating phlegm, the gypsum and the rhizoma anemarrhenae are ministerial medicines and have the effects of clearing heat and relieving cough and asthma, the bletilla striata and the scutellaria baicalensis are thin and have the effects of clearing heat and removing toxicity and astringing lung, and the raw liquorice is a guiding medicine and leads the meridian to have the effects of relieving cough and asthma. The traditional Chinese medicine composition can be used as a novel medicine for treating the early and middle stage coronary viral pneumonia.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the embodiments described are merely exemplary of the invention, and not of the invention in its entirety. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
Example 1
The embodiment provides a traditional Chinese medicine composition for treating novel coronavirus pneumonia in early and middle stages, which is prepared from the following raw materials:
9g of ephedra, 12g of almond, 20g of gypsum, 12g of rhizoma anemarrhenae, 15g of bletilla striata, 18g of scutellaria baicalensis and 9g of raw liquorice.
The preparation method of the traditional Chinese medicine composition for the novel early-stage and middle-stage coronary viral pneumonia comprises the following steps:
(1) weighing the raw materials according to the weight, drying the raw materials at 100 ℃ for 2 hours respectively, crushing the dried raw materials into 200 meshes, and uniformly mixing to obtain a mixed material;
(2) adding 5 times of water by mass into the mixed materials, decocting for 1.2h, and filtering to obtain a decoction, namely the traditional Chinese medicine composition for treating the novel coronavirus pneumonia in the early and middle stages.
The decoction of the traditional Chinese medicine composition is packaged into small bags, each bag is 150 ml, and the decoction is taken orally three times a day in the morning and evening.
Example 2
The embodiment provides a traditional Chinese medicine composition for treating novel coronavirus pneumonia in early and middle stages, which is prepared from the following raw materials:
6g of ephedra, 14g of almond, 15g of gypsum, 14g of rhizoma anemarrhenae, 12g of bletilla striata, 20g of scutellaria baicalensis and 6g of raw liquorice.
The preparation method of the traditional Chinese medicine composition for the novel early-stage and middle-stage coronary viral pneumonia comprises the following steps:
(1) weighing the raw materials according to the weight, drying the raw materials at 80 ℃ for 3 hours respectively, crushing the dried raw materials into 180 meshes, and uniformly mixing to obtain a mixed material;
(2) adding 2 times of water by mass into the mixed material, carrying out first decoction for 2 hours, filtering to obtain a first decoction and dregs, adding 2 times of water by mass into the dregs, carrying out decoction for 8 hours, filtering to obtain a second decoction, and uniformly mixing the first decoction and the second decoction;
(3) and (3) spray-drying the obtained decoction to obtain powder, namely the traditional Chinese medicine composition for treating the novel coronavirus pneumonia in the early and middle stages.
The powder is divided into small bags, each bag is 9g, and the bag is taken in the morning and at night, and the heavy person takes the powder with boiled water three times a day.
Example 3
The embodiment provides a traditional Chinese medicine composition for treating novel coronavirus pneumonia in early and middle stages, which is prepared from the following raw materials:
12g of ephedra, 10g of almond, 25g of gypsum, 10g of rhizoma anemarrhenae, 18g of bletilla striata, 16g of scutellaria baicalensis and 12g of raw liquorice.
The preparation method of the traditional Chinese medicine composition for the novel early-stage and middle-stage coronary viral pneumonia comprises the following steps:
(1) weighing the raw materials according to the weight, drying the raw materials at 120 ℃ for 1h respectively, crushing the dried raw materials into 220 meshes, and uniformly mixing to obtain a mixed material;
(2) adding 8 times of water by mass into the mixed materials, decocting for 0.5h for the first time, filtering to obtain a first decoction and dregs, adding 8 times of water by mass into the dregs, decocting for 0.5h, filtering to obtain a second decoction, and uniformly mixing the first decoction and the second decoction to obtain the traditional Chinese medicine composition for treating the novel coronavirus pneumonia in the early and middle stages.
Example 4
The embodiment provides a traditional Chinese medicine composition for treating novel coronavirus pneumonia in early and middle stages, which is prepared from the following raw materials:
9g of ephedra, 12g of almond, 20g of gypsum, 12g of rhizoma anemarrhenae, 15g of bletilla striata, 18g of scutellaria baicalensis and 9g of raw liquorice.
The preparation method of the traditional Chinese medicine composition for the novel early-stage and middle-stage coronary viral pneumonia comprises the following steps:
(1) weighing the raw materials according to the weight, drying the raw materials at 100 ℃ for 2 hours respectively, crushing the dried raw materials into 200 meshes, and uniformly mixing to obtain a mixed material;
(2) adding 5 times of water by mass into the mixed materials, decocting for 1.2 hours for the first time, filtering to obtain a first decoction and dregs, adding 5 times of water by mass into the dregs, decocting for 1.2 hours, filtering to obtain a second decoction, and uniformly mixing the first decoction and the second decoction to obtain the traditional Chinese medicine composition for treating the novel coronavirus pneumonia in the early and middle stages.
Specific cases
Zhao, female, age 45, Changchun, 2, month 2, 15 days 2020, general debilitation, cough with dyspnea, shortness of breath, fever, body temperature 37.8 ℃. Dizziness, cough with yellow sputum, yellow urine, dry stool. The traditional Chinese medicine of the example 1 is orally taken three times a day by 150 milliliters each time, the symptoms are obviously improved on the first day, all the symptoms disappear on the fourth day, the fever is recovered to be normal, and the body temperature is 36.5 ℃.
Sha some, female, 65 years old, Changchun. In 2020, 2, 17 days, the patient feels hypodynamia, diarrhea, cough and asthma, dizziness, fever, body temperature 37.5 ℃, dry mouth and short breath. The traditional Chinese medicine powder 9g described in the example 2 is taken three times a day, one bag is taken orally each time, warm water is taken, and the effect is remarkable the next day. The symptoms disappear more than the fifth day, and the body temperature returns to normal 35.5 ℃.
After 200 persons take the traditional Chinese medicine composition, relatives and friends of patients are infected with the new coronavirus, but no one of the patients who take the traditional Chinese medicine composition is infected with the new coronavirus.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (10)
1. A traditional Chinese medicine composition for treating novel coronavirus pneumonia in early and middle stages is characterized by comprising the following raw materials: 6-12 parts of ephedra, 10-14 parts of almond, 15-25 parts of gypsum, 10-14 parts of rhizoma anemarrhenae, 12-18 parts of bletilla striata, 16-20 parts of scutellaria baicalensis and 6-12 parts of raw liquorice.
2. The traditional Chinese medicine composition for early and medium stage novel coronary viral pneumonia according to claim 1, wherein the raw material components are: 9 parts of ephedra, 12 parts of almond, 20 parts of gypsum, 12 parts of rhizoma anemarrhenae, 15 parts of bletilla striata, 18 parts of scutellaria baicalensis and 9 parts of raw liquorice.
3. The preparation method of the traditional Chinese medicine composition for the early-stage and middle-stage novel coronary viral pneumonia according to any one of claims 1 to 2 is characterized by comprising the following steps:
(1) the preparation method comprises the following steps of taking the raw materials according to the weight parts, drying and crushing the raw materials respectively, and mixing the raw materials uniformly to obtain a mixed material;
(2) adding water into the mixed materials for decoction, and filtering to obtain a decoction liquid, thereby obtaining the traditional Chinese medicine composition for treating the novel coronavirus pneumonia in the early and middle stages.
4. The method according to claim 3, wherein the drying is carried out at a temperature of 80 to 120 ℃ for 1 to 3 hours in the step (1).
5. The method according to claim 4, wherein the drying is carried out at a temperature of 100 ℃ for a time of 2 hours.
6. The method as claimed in claim 3, wherein the particle size of the mixture is 180-220 mesh after pulverization in step (1).
7. The method according to claim 6, wherein in the step (1), the particle size of the mixed material after the pulverization is 200 mesh.
8. The preparation method according to claim 3, wherein in the step (2), the amount of water added is 2 to 8 times the amount of the mixture in the decoction.
9. The method according to claim 3, wherein the decocting is carried out for 0.5 to 2 hours in the step (2).
10. The preparation method of claim 3, wherein in the step (2), the decoction is repeated twice, the decoction dregs obtained by the first decoction are added with water for the second decoction, the filtration is carried out, the decoction dregs are discarded, and the decoction liquids obtained by the two decoctions are mixed to obtain the traditional Chinese medicine composition for treating the novel early-stage and middle-stage coronary viral pneumonia.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPWO2022071576A1 (en) * | 2020-10-02 | 2022-04-07 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2022071576A1 (en) * | 2020-10-02 | 2022-04-07 | ||
| WO2022071576A1 (en) * | 2020-10-02 | 2022-04-07 | 学校法人北里研究所 | Antiviral agent for preventing or treating covid-19 infection |
| JP7214080B2 (en) | 2020-10-02 | 2023-01-30 | 学校法人北里研究所 | Antiviral agent for prevention or treatment of novel coronavirus infection |
| CN116685215A (en) * | 2020-10-02 | 2023-09-01 | 学校法人北里研究所 | Antiviral agent for preventing or treating novel coronavirus infection |
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| CN112741878A (en) * | 2021-02-19 | 2021-05-04 | 徐修信 | Traditional Chinese medicine composition for treating wind-cold type novel coronary viral pneumonia and preparation method thereof |
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Application publication date: 20200703 |