CN111331911A - Tablet processing device and method - Google Patents

Tablet processing device and method Download PDF

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Publication number
CN111331911A
CN111331911A CN202010254067.3A CN202010254067A CN111331911A CN 111331911 A CN111331911 A CN 111331911A CN 202010254067 A CN202010254067 A CN 202010254067A CN 111331911 A CN111331911 A CN 111331911A
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China
Prior art keywords
tablet
forming
punch
plate
medicine
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Granted
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CN202010254067.3A
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Chinese (zh)
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CN111331911B (en
Inventor
王芳
朱俊芳
蔡莹莹
张华�
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First Affiliated Hospital of Zhengzhou University
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First Affiliated Hospital of Zhengzhou University
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Priority to CN202010254067.3A priority Critical patent/CN111331911B/en
Publication of CN111331911A publication Critical patent/CN111331911A/en
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Publication of CN111331911B publication Critical patent/CN111331911B/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B15/00Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/0023Drive arrangements for movable carriers, e.g. turntables
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B11/00Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005Coating of tablets or the like
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B11/00Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B30B11/10Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable intermittently rotated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B15/00Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/06Platens or press rams
    • B30B15/065Press rams
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B15/00Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/30Feeding material to presses
    • B30B15/302Feeding material in particulate or plastic state to moulding presses
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B15/00Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/32Discharging presses

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  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

The invention relates to the technical field of tablet processing equipment, in particular to a tablet processing device and a use method thereof, wherein the tablet processing device comprises a bottom plate, a control cabinet and a tablet forming machine platform, the control cabinet is arranged at the left end of the upper surface of the bottom plate, the tablet forming machine platform is arranged at the right side of the control cabinet, an L-shaped plate is fixed on the bottom plate at the rear side of the tablet forming machine platform, a hydraulic cylinder is arranged on the upper surface of the L-shaped plate, and the end part of a piston rod of the hydraulic cylinder, which penetrates through the top end of the L-shaped; the equipment disclosed by the invention can be used for continuously carrying out tabletting forming and coating treatment on the medicines, the efficiency of tabletting treatment is greatly improved through integrated flow treatment, automatic quantitative feeding and automatic ejection of the tablets from the forming punched holes can be realized, manual assistance is not needed, the effect of reducing the number of workers and improving the effect is realized, and the equipment is excellent in effect and strong in practicability.

Description

Tablet processing device and method
Technical Field
The invention relates to the technical field of tablet processing equipment, in particular to a tablet processing device and method.
Background
Tablets are a common form of medicine, and are prepared by tabletting medicine powder into round or other regular shapes through a mould and then coating the tablets. In the preforming forming process of tablet, the biggest problem that exists is behind the powdered drug compression moulding, its fashioned tablet is located the mould, the tablet is difficult for taking out from the mould, and need artifically add the powdered drug to the shaping control at the fashioned in-process of preforming, not only inefficiency, and the volume of adding the powdered drug can't obtain accurate control, behind the forming process, need carry it into the tablet coating machine through a plurality of conveyer and carry out the capsule processing, and inside traditional tablet coating machine put into the cylinder with the tablet, spray the coating liquid to the cylinder, because once only handle a large amount of tablets, the coating liquid is gone up in the unable even parcel of its tablet, make the composition of tablet lose prematurely.
For example, the invention with the patent number CN107584798A discloses a tablet forming and pressing machine, which comprises a bracket, a supporting platform arranged on the bracket, an upper die and a lower die, wherein the lower die is disc-shaped and is arranged on the supporting platform and is linked with a motor in the supporting platform, the upper die comprises a circular platform and a cylindrical upper pressing punch arranged at the lower end of the circular platform, the upper pressing punch is circularly distributed on the circular platform, the supporting platform is disc-shaped, the upper pressing punch is provided with lower pressing punches corresponding to the upper pressing punches one by one, the lower die is provided with forming holes adapted to the upper and lower pressing punches, the lower pressing punches are provided with a material leaking hole between two by two, the material leaking hole and the lower pressing punches are crossed and uniformly distributed on the same circumference, a collecting box is arranged below the supporting platform, although the tablet forming and pressing machine can form a plurality of tablets at one time, the production efficiency is greatly improved, and the tablet forming and the tablet, and manual material taking is needed after tabletting and forming, so that the production efficiency of the whole device is bound to a certain extent. Also, for example, the invention with the patent number CN107890425A discloses a tablet coating apparatus, which comprises an operation chamber, a spray gun, an air injection device, a feeding device and a recovery device, wherein the spray gun is arranged at the bottom of the operation chamber, and the air injection device comprises a sleeve sleeved outside the spray gun, an air injection channel arranged in the sleeve and an injection member connected with the air injection channel; the injection piece is arranged obliquely; the device does not allow the tablet coating process to be more uniform by the inclined spray member when coating the tablets. Therefore, in view of the above-mentioned shortcomings of the existing devices, it is a technical problem to be solved to design a tablet processing device for tablet forming and coating.
Disclosure of Invention
The invention aims to overcome the defects of the conventional tablet tabletting and forming device and the conventional tablet coating equipment, and designs a tablet processing device integrating tabletting, forming and coating processing.
The invention is realized by the following technical scheme:
the utility model provides a tablet processing apparatus, major structure includes bottom plate, switch board and preforming shaping board, sets up the left end at the bottom plate upper surface with the switch board, and preforming shaping board sets up the right side at the switch board. Be located and be fixed with the L template on the rear side bottom plate of preforming shaping board, the upper surface of L template is provided with the pneumatic cylinder, and the end connection that the piston rod of pneumatic cylinder passed L template top has the pressure disk, and the pressure disk lower surface is provided with a plurality of preforming drifts, and a plurality of preforming drifts, extrusion drift setting are on the concentric ring of pressure disk, and the pressure disk lower surface that is located a plurality of preforming drifts offsides is provided with a plurality of extrusion drifts, and the quantity of extrusion drift is corresponding with the quantity of preforming drift. Further, the axial length of the extrusion punch is slightly longer than that of the tablet punch. The forming circular die disc is arranged under the pressure plate, a plurality of forming punched holes are formed in the upper surface of the forming circular die disc, the cross sections of the forming punched holes, the pressing punch and the extruding punch are circular, and the forming punched holes can correspond to the pressing punch and the extruding punch. The center of the lower surface of the molding circular die disc is connected with a rotating shaft, and a power mechanism for driving the rotating shaft to rotate intermittently is arranged inside the tabletting molding machine table;
an upright column is fixed on a bottom plate positioned beside the L-shaped plate, the upper end of the upright column is connected with a powder hopper, the lower end of the powder hopper is connected with a discharge pipe, the lower end of the discharge pipe is connected with a powder accumulation ring plate, the powder accumulation ring plate is arranged above a forming punch hole on a forming circular die disc, and the lower end of the powder accumulation ring plate is attached to the upper surface of the forming circular die disc;
the tablet forming machine comprises a tablet forming machine table, and is characterized in that a tablet forming box body is arranged on the right side of the tablet forming machine table, a feed inlet is formed in the left side face of the tablet forming box body, a guide hopper is arranged on the feed inlet, a feed inlet of the guide hopper is formed below the right end of a forming circular die disc, a plurality of guide support columns are arranged below a feed inlet end of the guide hopper, and the guide support columns are used for supporting the guide hopper to be arranged above the tablet forming machine table. The whole guide hopper is obliquely arranged so as to conveniently convey the tablets into the coating box body. The right side of capsule box is provided with capsule liquid storage jar, the upper surface of capsule box is provided with the peristaltic pump, be provided with the feed liquor pipe that inserts capsule liquid storage jar on the peristaltic pump, the other end of peristaltic pump is provided with the drain pipe that inserts the capsule box inside, be provided with the shower nozzle on the drain pipe, be located the capsule box upper surface of peristaltic pump side is provided with the air pump, be connected with the compressed air pipe that inserts the capsule box inside on the air pump, compressed air pipe's lower extreme is connected with the drain pipe lower extreme, the inside screen frame that sprays that is provided with of capsule box, the trailing flank of capsule box is provided with the discharge gate.
The lower end face of the forming circular die disc is provided with a medicine pressing chassis, the medicine pressing chassis is attached to the lower end face of the circular die disc, the main body shape structure of the medicine pressing chassis is integrally of a fan-shaped structure with a gap angle of α, a plurality of supporting columns are arranged below the medicine pressing chassis, the medicine pressing chassis can be supported and arranged above the tabletting forming machine table through the supporting columns, the gap positions correspond to the feeding port ends of the material guide hoppers, and the whole number of forming punched holes corresponding to the number of the extruding punches can be surrounded in the range of the gap.
As a further arrangement of the above scheme, the power mechanism comprises a stepping motor and a control end PLC, the control end PLC is connected with the stepping motor, and an output shaft of the stepping motor is connected with the lower end of the rotating shaft.
As a further arrangement of the above scheme, the power mechanism comprises a driving motor, an incomplete gear and a complete gear, an output shaft of the driving motor is connected with the incomplete gear, and the complete gear is connected with the lower end of the rotating shaft.
As a further arrangement of the above scheme, the power mechanism includes a driving motor, a first disc and a second disc, the first disc is connected with an output shaft of the driving motor, a poking protruding rod is arranged on a circumferential side surface of the first disc, the second disc is connected with a lower end of the rotating shaft, a plurality of poking rods are arranged on a lower surface of the second disc, and the poking protruding rod is arranged between two adjacent poking rods.
As a further arrangement of the above scheme, the left end of the spraying screen frame is rotatably arranged on the inner wall of the coating box body, the bottom wall of the coating box body is connected with a spring, the upper end of the spring is connected with the right end of the spraying screen frame, the front side surface of the coating box body is provided with a vibrating motor, the output shaft of the vibrating motor is connected with a cam, and the cam is abutted to the lower surface of the spraying screen frame.
As a further arrangement of the above scheme, the cross-sectional shapes of the tabletting punch and the forming punch are circular or regular polygon.
As a further arrangement of the scheme, the lower end of the upright post is connected with a reinforcing rod, and the outer end of the reinforcing rod is connected with the discharge pipe.
As a further arrangement of the scheme, a flow regulating valve is arranged on the discharge pipe.
As a further arrangement of the scheme, a liquid level meter is arranged on the outer side wall of the coating liquid storage tank.
Has the beneficial effects.
1. Compared with the prior art, the invention only needs to manually inject sufficient powder medicine into the medicine powder hopper, powder medicine enters the powder accumulation annular plate along the discharge pipe, and when an empty forming punching hole passes through the powder accumulation annular plate in the process of driving the forming circular die disc to rotate by the power mechanism, the powder can fall into the forming punch hole, the forming punch hole above the tabletting forming top block is filled with powder medicine, then the powder medicine is rotated to be under the tabletting punch head, at the moment, the hydraulic cylinder drives the pressure plate to move downwards, the tabletting punch head enters the forming punch hole filled with the powder medicine to compact the powder medicine into tablets, the forming punch hole after the tabletting forming rotates to the position right below the extrusion punch head, the hydraulic cylinder drives the pressure plate to press down again, the extrusion punch head extrudes the tablets from the forming punch hole, and the tablets can fall to the feeding hole of the material guide hopper due to the notch arranged on the tablet pressing base plate. Because the guide hopper is arranged obliquely, the tablets can slide into the coating box. And the tablet falls into the guide fill and gets into and sprays the reel, and the tablet receives the coating liquid after the atomizing to be handled at the process that sprays the reel whereabouts, can carry out even coating to the tablet and handle, handles the discharge gate after accomplishing and discharges. The equipment disclosed by the invention can be used for continuously carrying out tabletting forming and coating treatment on the medicines, the efficiency of tabletting treatment is greatly improved through integrated flow treatment, automatic quantitative feeding and automatic ejection of the tablets from the forming punched holes can be realized, manual assistance is not needed, the effect of reducing the number of workers and improving the effect is realized, and the equipment is excellent in effect and strong in practicability.
2. The spraying sieve frame is arranged in a rotating mode, the vibrating motor drives the cam to rotate and is under the action of the spring, so that tablets falling into the spraying sieve frame can be vibrated and discarded, the tablets can receive the coating liquid sprayed out of the spray head in all directions in the air for treatment, the treated tablets can be completely coated with the coating liquid, the shelf life of the whole tablets is greatly prolonged, and the market competitiveness of products is improved.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a first angle perspective view of the present invention.
Fig. 2 is a second perspective view of the present invention.
Fig. 3 is a perspective view of the platen according to the present invention.
FIG. 4 is an internal cross-sectional view of a circular die plate for molding in accordance with the present invention.
Fig. 5 is a perspective view showing the construction of the powder hopper, the discharge pipe and the powder accumulation ring plate according to the present invention.
Fig. 6 is a perspective view showing a material guide hopper and a material guide plate according to the present invention.
FIG. 7 is a front plan view of the interior of the coating tank of the present invention.
Fig. 8 is a cross-sectional view taken at a-a in fig. 7.
Fig. 9 is a perspective view of the power mechanism according to embodiment 2.
Fig. 10 is a perspective view of the power mechanism according to embodiment 3.
Fig. 11 is a structural view of the pressing base plate.
Wherein, 1-a bottom plate, 2-a control cabinet, 3-a tablet forming machine, 4-an L-shaped plate, 5-a hydraulic cylinder, 6-a pressure plate, 601-a tablet punch, 602-a press punch, 7-a forming circular mould, 701-a forming punch, 8-a rotating shaft, 9-a power mechanism, 901-a driving motor, 902-an incomplete gear, 903-a complete gear, 904-a first disc, 9041-a toggle convex rod, 905-a second disc, 9051-a toggle rod, 10-a vertical column, 101-a reinforcing rod, 11-a powder hopper, 12-a discharge pipe, 121-a flow regulating valve, 13-a powder accumulation ring plate, 14-a coating box body, 15-a feed inlet, 16-a guide hopper, 17-a guide support column and 18-a coating liquid storage tank, 181-a liquid level meter, 19-a peristaltic pump, 20-a liquid inlet pipe, 21-a liquid outlet pipe, 22-a spray head, 23-an air pump, 24-a compressed air pipe, 25-a spray screen frame, 26-a discharge port, 27-a spring, 28-a vibration motor, 29-a cam and 30-a medicine pressing chassis.
Detailed Description
In order to make the technical solutions better understood by those skilled in the art, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only partial embodiments of the present application, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail with reference to the accompanying drawings 1 to 11, in conjunction with the embodiments.
Example 1
This embodiment 1 has introduced a tablet processing apparatus, and major structure includes bottom plate 1, switch board 2 and preforming shaping board 3, sets up switch board 2 at the left end of 1 upper surface of bottom plate, and preforming shaping board 3 sets up the right side at switch board 2. Be located and be fixed with L template 4 on the rear side bottom plate 1 of preforming forming machine 3, the upper surface of L template 4 is provided with pneumatic cylinder 5, the end connection that the piston rod of pneumatic cylinder 5 passed L template 4 top has pressure disk 6, pressure disk 6 lower surface is provided with a plurality of preforming drift 601, extrusion drift 602, a plurality of preforming drift 601, extrusion drift 602 sets up on the concentric ring of pressure disk 6, the pressure disk 6 lower surface that is located a plurality of preforming drift 601 offsides is provided with a plurality of extrusion drift 602, the quantity of extrusion drift 602 is corresponding with the quantity of preforming drift 601. The axial length of the extrusion punch 602 is slightly longer than that of the tablet-pressing punch 601 so that the tablet can be extruded from the forming punch 701.
A forming circular die disc 7 is arranged right below the pressure plate 6, a plurality of forming punched holes 701 are formed in the upper surface of the forming circular die disc 7, the cross sections of the forming punched holes 701, the tabletting punch 601 and the extruding punch 602 are all circular, and the positions of the forming punched holes 701 can correspond to the tabletting punch 601 and the extruding punch 602. The lower surface center department of shaping circular mould dish 7 is connected with pivot 8, and pivot 8 transmits rotary motion to shaping circular mould dish 7. The inside of preforming forming board 3 is provided with 8 intermittent type formulas pivoted power unit 9 of drive pivot, and power unit 9 in this embodiment includes step motor (not drawn in the picture) and control end PLC (not drawn in the picture), is connected control end PLC with step motor, is connected step motor's output and pivot 8, carries the pulse signal for step motor through PLC control and realizes step motor's intermittent type formula fixed angle rotation.
Be located and be fixed with stand 10 on the bottom plate 1 of L template 4 side, the upper end of stand 10 is connected with powder hopper 11, the lower extreme of powder hopper 11 is connected with discharging pipe 12, still be connected with stiffener 101 at the lower extreme of stand 10 simultaneously, the outer end of stiffener 101 is connected with discharging pipe 12, and set up flow control valve 121 on discharging pipe 12, it piles up the crown plate 13 to be connected with the powder at the lower extreme of discharging pipe 12, the powder is piled up the crown plate 13 and is set up the top that the shaping punched a hole 701 on the circular mould dish 7 of shaping, and the lower extreme laminating of crown plate 13 is piled up at the upper surface of the circular mould dish 7 of shaping, when empty shaping punches a hole 701 and rotates to the powder and piles up the crown plate 13, the powder medicine can fill the shaping.
The right side that is located preforming shaping board 3 is provided with coating box 14, and feed inlet 15 has been seted up to the left surface of coating box 14, is provided with guide hopper 16 on the feed inlet 15, and the pan feeding mouth setting of guide hopper 16 is in the circular die disc 7 right-hand member below of shaping, and the below of the pan feeding mouth end of guide hopper 16 is provided with a plurality of guide support posts 17, and guide support posts 17 are used for supporting guide hopper 16 and set up in the top of preforming shaping board 3. The material guide hopper 16 is disposed to be inclined as a whole so as to easily convey the tablets to the coating tank 14.
The right side of the coating tank body 14 is provided with a coating liquid storage tank 18, and the outer side wall of the coating liquid storage tank 18 is provided with a liquid level meter 181, so that the liquid level inside the tank can be observed conveniently. The upper surface of the coating box body 14 is provided with a peristaltic pump 19, the peristaltic pump 19 is provided with a liquid inlet pipe 20 inserted into the coating liquid storage tank 18, the other end of the peristaltic pump 19 is provided with a liquid outlet pipe 21 inserted into the coating box body 14, the liquid outlet pipe 21 is provided with a spray head 22, the upper surface of the coating box body 14 beside the peristaltic pump 19 is provided with an air pump 23, the air pump 23 is connected with a compressed air pipe 24 inserted into the coating box body 14, the lower end of the compressed air pipe 24 is connected with the lower end of the liquid outlet pipe 21, the coating box body 14 is internally provided with a spray screen frame 25, and the rear side surface of the coating box body 14 is provided.
The lower end face of the forming circular die disc 7 is provided with a medicine pressing chassis 30, the medicine pressing chassis 30 is attached to the lower end face of the circular die disc 7, the main shape structure of the medicine pressing chassis 30 is as shown in fig. 11, the whole body is of a fan-shaped structure with a notch angle of α, a plurality of support columns are arranged below the medicine pressing chassis 30, the medicine pressing chassis 30 can be supported and arranged above the tabletting forming machine table 3 through the support columns, the notch positions correspond to the material inlet ends of the material guide hoppers 16, and the whole number of forming punched holes 701 corresponding to the number of the extruding punches 602 can be enclosed in the range of the notch, the motion matching relationship of the rotating shaft 8, the forming circular die disc 7 and the medicine pressing chassis 30 is in sliding connection, namely, the rotating shaft 8 can drive the forming circular die disc 7 to slide and rotate along the surface of the medicine pressing chassis 30.
Example 2
Embodiment 2 is another option of the actuating mechanism 9 based on embodiment 1, and a certain improvement is also made to the spray screen frame 25, which is specifically described below:
the center of the lower surface of the forming circular mold 7 is connected with a rotating shaft 8, a power mechanism 9 for driving the rotating shaft to intermittently rotate is arranged inside the tablet forming machine table 3, the power mechanism 9 in the embodiment comprises a driving motor 901, an incomplete gear 902 and a complete gear 903 (refer to the attached drawing 9), an output shaft of the driving motor 901 is connected with the incomplete gear 902, the complete gear 903 is connected with the lower end of the rotating shaft 8, and the intermittent fixed-angle rotation of the forming circular mold 7 can be realized through the continuous rotation of the driving motor 901.
Be located and be fixed with stand 10 on the bottom plate 1 of L template 4 side, the upper end of stand 10 is connected with powder hopper 11, the lower extreme of powder hopper 11 is connected with discharging pipe 12, still be connected with stiffener 101 at the lower extreme of stand 10 simultaneously, the outer end of stiffener 101 is connected with discharging pipe 12, and set up flow control valve 121 on discharging pipe 12, it piles up the crown plate 13 to be connected with the powder at the lower extreme of discharging pipe 12, the powder is piled up the crown plate 13 and is set up the top that the shaping punched a hole 701 on the circular mould dish 7 of shaping, and the lower extreme laminating of crown plate 13 is piled up at the upper surface of the circular mould dish 7 of shaping, when empty shaping punches a hole 701 and rotates to the powder and piles up the crown plate 13, the powder medicine can fill the shaping.
The right side of the coating tank body 14 is provided with a coating liquid storage tank 18, and the outer side wall of the coating liquid storage tank 18 is provided with a liquid level meter 181, so that the liquid level inside the tank can be observed conveniently. A peristaltic pump 19 is arranged on the upper surface of the coating box body 14, a liquid inlet pipe 20 inserted into a coating liquid storage tank 18 is arranged on the peristaltic pump 19, a liquid outlet pipe 21 inserted into the coating box body 14 is arranged at the other end of the peristaltic pump 19, a spray nozzle 22 is arranged on the liquid outlet pipe 21, an air pump 23 is arranged on the upper surface of the coating box body 14 beside the peristaltic pump 19, a compressed air pipe 24 inserted into the coating box body 14 is connected to the air pump 23, the lower end of the compressed air pipe 24 is connected with the lower end of the liquid outlet pipe 21, a spray screen frame 25 is arranged inside the coating box body 14, the left end of the spray screen frame 25 is rotatably arranged on the inner wall of the coating box body 14, a spring 27 is connected to the bottom wall of the coating box body 14, the upper end of the spring 27 is connected with the right end of the spray screen frame 25, a vibration motor 28 is arranged on the front side surface of the coating box body 14, a cam 29 is connected to the output, the rear side of the coating box body 14 is provided with a discharge hole 26, and the vibration of the spraying screen frame 25 is realized through the action of a cam 29 and a spring 27, so that the coating treatment effect is improved.
Example 3
Embodiment 3 is another option of the power mechanism 9 based on embodiment 2, and is specifically described below with reference to fig. 10:
the same parts of this embodiment as those of embodiment 2 are not described again, but the difference is that the power mechanism 9 includes a driving motor 901, a first disk 904 and a second disk 905, the first disk 904 is connected to an output shaft of the driving motor 901, a toggle protruding rod 9041 is disposed on the circumferential side surface of the first disk 904, the second disk 905 is connected to the lower end of the rotating shaft 8, a plurality of toggle rods 9051 are disposed on the lower surface of the second disk 905, and the toggle protruding rod 9041 is disposed between two adjacent toggle rods 9051; the intermittent fixed-angle rotation of the rotating shaft 8 can be realized by different rotations of the driving motor 901.
Example 4
The control cabinet 2 of this embodiment is provided with a plurality of control switches, and the host computer part is the PLC controller, is connected to corresponding control switch through the control pencil and is connected to pneumatic cylinder 5, flow control valve 121, driving motor 9, peristaltic pump 19, air pump 23, vibrating motor 28 to realize the automatic intelligent control of tablet processing apparatus.
Description of the working principle:
when the tablet processing device works, firstly, medicine is added into a medicine powder hopper 11, a flow regulating valve 121 on a discharge pipe 12 is opened, and the medicine flows into a powder material accumulation annular plate 13; when the empty forming punch 701 rotates into the powder accumulation annular plate 13, the powder medicament can fill the forming punch 701; the hydraulic cylinder 5 drives the pressure plate 6 to press downwards, the tabletting punch 601 can press the forming punch 701 filled with the medicine materials, and tablets are obtained through pressing; the hydraulic cylinder 5 drives the pressure plate 6 to lift upwards, the forming circular die plate 7 rotates, and the forming punch 701 pressed with tablets rotates to the material inlet end of the material guide hopper 16; the hydraulic cylinder 5 drives the pressure plate 6 to press down again, and the tablet can be pressed out of the forming punch 701 by the extrusion punch 602 due to the notch arranged on the medicine pressing base plate 30, and can fall to the feeding port of the material guide hopper 16. The guiding hopper 16 is inclined so that the tablets can slide into the coating box 14.
The use method of the tablet processing device comprises the following steps:
s1, adding the medicine materials into a medicine powder hopper;
s2, opening a flow control valve on the discharge pipe, and enabling the powder medicine to flow into the powder accumulation annular plate;
s3, controlling the power mechanism to act, and driving the rotating shaft to drive the forming circular mould disc to rotate intermittently; when the empty forming punched hole rotates to the powder accumulation annular plate, powder medicine can be filled in the forming punched hole;
s4, controlling the hydraulic cylinder to act, driving the pressure plate to press downwards, pressing the tablet punch head into the molding punch hole filled with the medicine, and pressing to obtain tablets;
s5, controlling the hydraulic cylinder to act, and driving the pressure plate to lift up by the hydraulic cylinder; controlling a power mechanism to act, rotating a forming circular die disc, and rotating a forming punched hole pressed with tablets to a material inlet end of a material guide hopper;
s6, controlling the hydraulic cylinder to act, driving the pressure plate to press downwards again by the hydraulic cylinder, pressing the tablets out of the forming punched holes by the pressing punch, and enabling the tablets to fall to a feeding port of the material guide hopper and slide into the coating box;
s7, controlling the spraying mechanism to act, pumping coating liquid by the peristaltic pump, and delivering compressed gas by the air pump, so that the coating liquid forms spray from the spray head and sprays to the tablets below;
s8, controlling the vibration mechanism to act, driving the spraying screen frame to vibrate up and down by the vibration motor, driving the tablets to vibrate up and down, treating the tablets by the atomized coating liquid in vibration, and forming uniform coatings on the tablets.
Therefore, the invention conveniently realizes the pressing and punching of the tablets by utilizing the hydraulic cylinder to press and the rotating shaft intermittent rotating mechanism. Still will spray the reel and rotate the setting, rotate and receive the effect of spring through vibrating motor drive cam to can vibrate the tablet that falls into to spray in the reel and abandon, and the tablet can all-round accept in the air from the shower nozzle spun coating liquid and handle, coating liquid can be wrapped up in to the tablet after the processing comprehensively.
The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. The tablet processing device comprises a bottom plate (1), a control cabinet (2) and a tablet forming machine table (3), and is characterized in that the control cabinet (2) and the tablet forming machine table (3) are arranged on the bottom plate (1).
2. The tablet processing device according to claim 1, wherein the control cabinet (2) is arranged at the left end of the upper surface of the bottom plate (1), the tablet forming machine table (3) is arranged at the right side of the control cabinet (2), an L-shaped plate (4) is fixed on the bottom plate (1) at the rear side of the tablet forming machine table (3), a hydraulic cylinder (5) is arranged on the upper surface of the L-shaped plate (4), a pressure plate (6) is connected with the end part of a piston rod of the hydraulic cylinder (5) penetrating through the top end of the L-shaped plate (4), a plurality of tablet punches (601) and extrusion punches (602) are arranged on the lower surface of the pressure plate (6), the tablet punches (601) and the extrusion punches (602) are arranged on the concentric rings of the pressure plate (6), and the extrusion punches (602) are arranged at the opposite side of the tablet punches (601); the number of the extrusion punches (602) corresponds to the number of the tabletting punches (601), and the axial length of the extrusion punches (602) is longer than the length of the tabletting punches (601); a forming circular die disc (7) is arranged right below the pressing disc (6), a plurality of forming punched holes (701) are formed in the upper surface of the forming circular die disc (7), and the positions of the forming punched holes (701) can correspond to the pressing punch (601) and the extruding punch (602); a rotating shaft (8) is connected to the center of the lower surface of the forming circular die disc (7), and a power mechanism (9) for driving the rotating shaft (8) to rotate intermittently is arranged inside the tabletting forming machine table (3);
an upright column (10) is fixed on the bottom plate (1) located beside the L-shaped plate (4), the upper end of the upright column (10) is connected with a powder hopper (11), the lower end of the powder hopper (11) is connected with a discharge pipe (12), the lower end of the discharge pipe (12) is connected with a powder accumulation ring plate (13), the powder accumulation ring plate (13) is arranged above a forming punch hole (701) on the forming circular die disc (7), and the lower end of the powder accumulation ring plate (13) is attached to the upper surface of the forming circular die disc (7);
a coating box body (14) is arranged on the right side of the tabletting forming machine table (3), a feeding hole (15) is formed in the left side surface of the coating box body (14), a material guide hopper (16) is arranged on the feeding hole (15), a feeding hole of the material guide hopper (16) is arranged below the right end of the forming circular die disc (7), a plurality of material guide supporting columns (17) are arranged below the feeding hole end of the material guide hopper (16), and the material guide supporting columns (17) are used for supporting the material guide hopper (16) above the tabletting forming machine table (3); the material guide hopper 16 is integrally arranged in an inclined way, the right side of the coating box body (14) is provided with a coating liquid storage tank (18), a peristaltic pump (19) is arranged on the upper surface of the coating box body (14), a liquid inlet pipe (20) inserted into a coating liquid storage tank (18) is arranged on the peristaltic pump (19), the other end of the peristaltic pump (19) is provided with a liquid outlet pipe (21) inserted into the coating box body (14), a spray head (22) is arranged on the liquid outlet pipe (21), an air pump (23) is arranged on the upper surface of the coating box body (14) which is positioned beside the peristaltic pump (19), the air pump (23) is connected with a compressed air pipe (24) inserted into the coating box body (14), the lower end of the compressed air pipe (24) is connected with the lower end of the liquid outlet pipe (21), a spraying screen frame (25) is arranged in the coating box body (14), and a discharge hole (26) is formed in the rear side surface of the coating box body (14);
the forming circular die disc (7) is provided with a medicine pressing base plate (30) on the lower end face, the medicine pressing base plate (30) is attached to the lower end surface of the circular die disc (7), the main body shape structure of the medicine pressing base plate (30) is a fan-shaped structure with a notch angle of α, the position of the notch corresponds to the material inlet end of the material guide hopper (16), the rotating shaft (8), the forming circular die disc (7) and the medicine pressing base plate (30) are in sliding connection in a motion matching relation, the rotating shaft (8) can drive the forming circular die disc (7) to slide and rotate along the surface of the medicine pressing base plate (30), the forming punch holes (701) with the number corresponding to the number of the extruding punch heads (602) can be enclosed within the range of the notch angle α, the power mechanism (9) comprises a stepping motor and a control end PLC, the control end PLC is connected with the stepping motor, and the output shaft of the stepping motor is connected with the lower end of the rotating shaft (.
3. A tablet-handling device according to claim 2, characterized in that the power unit (9) comprises a drive motor (901), a partial gear (902) and a full gear (903), the output shaft of the drive motor (901) being connected to the partial gear (902) and the full gear (903) being connected to the lower end of the shaft (8).
4. The tablet processing device according to claim 2, wherein the power mechanism (9) comprises a driving motor (901), a first disk (904) and a second disk (905), the first disk (904) is connected with an output shaft of the driving motor (901), a shifting convex rod (9041) is arranged on the circumferential side surface of the first disk (904), the second disk (905) is connected with the lower end of the rotating shaft (8), a plurality of shifting rods (9051) are arranged on the lower surface of the second disk (905), and the shifting convex rod (9041) is arranged between two adjacent shifting rods (9051).
5. A tablet processing apparatus according to claim 2, wherein the left end of the spraying screen frame (25) is rotatably disposed on the inner wall of the coating box (14), the bottom wall of the coating box (14) is connected with a spring (27), the upper end of the spring (27) is connected with the right end of the spraying screen frame (25), the front side of the coating box (14) is provided with a vibration motor (28), the output shaft of the vibration motor (29) is connected with a cam (29), and the cam (29) abuts against the lower surface of the spraying screen frame (25).
6. A tablet-handling device according to claim 2, where the cross-sectional shape of the tabletting punch (601), the pressing punch (602) and the forming punch (701) is circular or regular polygonal.
7. A tablet-handling device according to claim 2, characterized in that a reinforcing rod (101) is connected to the lower end of the upright (10), the outer end of the reinforcing rod (101) being connected to the outlet pipe (12).
8. A tablet processing device according to claim 2, characterized in that the outlet pipe (12) is provided with a flow regulating valve (121).
9. A tablet-handling device according to claim 2, where the coating liquid storage tank (18) is provided with a level gauge (181) on its outer side wall.
10. A method of using a tablet-processing device according to claims 1-9, wherein the tablet-processing device used is a tablet-processing device, characterized in that the method comprises the steps of:
s1, adding the medicine materials into a medicine powder hopper;
s2, opening a flow control valve on the discharge pipe, and enabling the powder medicine to flow into the powder accumulation annular plate;
s3, controlling the power mechanism to act, and driving the rotating shaft to drive the forming circular mould disc to rotate intermittently; when the empty forming punched hole rotates to the powder accumulation annular plate, powder medicine can be filled in the forming punched hole;
s4, controlling the hydraulic cylinder to act, driving the pressure plate to press downwards, pressing the tablet punch head into the molding punch hole filled with the medicine, and pressing to obtain tablets;
s5, controlling the hydraulic cylinder to act, and driving the pressure plate to lift up by the hydraulic cylinder; controlling a power mechanism to act, rotating a forming circular die disc, and rotating a forming punched hole pressed with tablets to a material inlet end of a material guide hopper;
s6, controlling the hydraulic cylinder to act, driving the pressure plate to press downwards again by the hydraulic cylinder, pressing the tablets out of the forming punched holes by the pressing punch, and enabling the tablets to fall to a feeding port of the material guide hopper and slide into the coating box;
s7, controlling the spraying mechanism to act, pumping coating liquid by the peristaltic pump, and delivering compressed gas by the air pump, so that the coating liquid forms spray from the spray head and sprays to the tablets below;
s8, controlling the vibration mechanism to act, driving the spraying screen frame to vibrate up and down by the vibration motor, driving the tablets to vibrate up and down, treating the tablets by the atomized coating liquid in vibration, and forming uniform coatings on the tablets.
CN202010254067.3A 2020-04-02 2020-04-02 Tablet processing device and method Expired - Fee Related CN111331911B (en)

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CN202010254067.3A CN111331911B (en) 2020-04-02 2020-04-02 Tablet processing device and method

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Cited By (7)

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Publication number Priority date Publication date Assignee Title
CN112440502A (en) * 2020-11-12 2021-03-05 安徽草珊瑚生物科技有限公司 Throat-moistening buccal tablet tabletting forming machine
CN112590291A (en) * 2020-12-04 2021-04-02 重庆医药高等专科学校 Tabletting device for pharmacy
CN112622333A (en) * 2020-12-24 2021-04-09 安徽草珊瑚生物科技有限公司 A raw materials compaction equipment for fresh and cool buccal tablet preparation
CN113172926A (en) * 2021-04-27 2021-07-27 吕其玉 Tablet forming device for bioengineering
CN113768038A (en) * 2021-09-14 2021-12-10 江苏省协同医药生物工程有限责任公司 Accurate quantitative experimental animal functional feed and preparation method and equipment
CN114986972A (en) * 2022-05-23 2022-09-02 罗田县新普生药业有限公司 Melatonin multi-specification tabletting and charging equipment and tabletting and charging method thereof
CN117244997A (en) * 2023-11-16 2023-12-19 山西富兴通重型环锻件有限公司 Flange punching device

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Publication number Priority date Publication date Assignee Title
CN112440502A (en) * 2020-11-12 2021-03-05 安徽草珊瑚生物科技有限公司 Throat-moistening buccal tablet tabletting forming machine
CN112590291A (en) * 2020-12-04 2021-04-02 重庆医药高等专科学校 Tabletting device for pharmacy
CN112622333A (en) * 2020-12-24 2021-04-09 安徽草珊瑚生物科技有限公司 A raw materials compaction equipment for fresh and cool buccal tablet preparation
CN113172926A (en) * 2021-04-27 2021-07-27 吕其玉 Tablet forming device for bioengineering
CN113172926B (en) * 2021-04-27 2023-09-01 济南高华制药有限公司 Tablet forming device for bioengineering
CN113768038A (en) * 2021-09-14 2021-12-10 江苏省协同医药生物工程有限责任公司 Accurate quantitative experimental animal functional feed and preparation method and equipment
CN114986972A (en) * 2022-05-23 2022-09-02 罗田县新普生药业有限公司 Melatonin multi-specification tabletting and charging equipment and tabletting and charging method thereof
CN114986972B (en) * 2022-05-23 2023-03-14 罗田县新普生药业有限公司 Melatonin multi-specification tabletting and charging equipment and tabletting and charging method thereof
CN117244997A (en) * 2023-11-16 2023-12-19 山西富兴通重型环锻件有限公司 Flange punching device
CN117244997B (en) * 2023-11-16 2024-01-30 山西富兴通重型环锻件有限公司 Flange punching device

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