CN111202774A - Traditional Chinese medicine composition for treating arthralgia and myalgia and method - Google Patents

Traditional Chinese medicine composition for treating arthralgia and myalgia and method Download PDF

Info

Publication number
CN111202774A
CN111202774A CN201811310990.3A CN201811310990A CN111202774A CN 111202774 A CN111202774 A CN 111202774A CN 201811310990 A CN201811310990 A CN 201811310990A CN 111202774 A CN111202774 A CN 111202774A
Authority
CN
China
Prior art keywords
traditional chinese
chinese medicine
medicine composition
pain
root
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811310990.3A
Other languages
Chinese (zh)
Inventor
常瑞安
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201811310990.3A priority Critical patent/CN111202774A/en
Publication of CN111202774A publication Critical patent/CN111202774A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to a traditional Chinese medicine composition for treating arthralgia and myalgia and a method thereof, wherein each gram of the traditional Chinese medicine composition comprises the following components in parts by weight: 0.17 to 0.18 g of astragalus root, 0.23 to 0.24 g of clematis root, 0.14 to 0.15 g of atractylodes macrocephala koidz, 0.14 to 0.15 g of monkshood, 0.14 to 0.15 g of ephedra herb and 0.14 to 0.15 g of trogopterus dung. The important composition of the invention has good curative effect, short course of treatment, high cure rate and no side effect. The traditional Chinese medicine composition has the effects of expelling wind and clearing away cold, promoting blood circulation and relieving pain, and has good curative effects on cold and pain caused by trauma, sciatica, lumbar disc herniation, lumbocrural pain, scapulohumeral periarthritis, cervical vertebra numbness, traumatic injury sequelae, rheumatism, rheumatoid diseases, postpartum body pain caused by wind-cold and the like.

Description

Traditional Chinese medicine composition for treating arthralgia and myalgia and method
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating arthralgia and myalgia and a method thereof.
Background
Pain is one of the most prominent clinical manifestations of the patient, it brings the patient a very large through hole, especially the pain of bones and muscles is more unbearable.
In recent years, the common diseases of the old, such as muscle and bone pain, spread in middle-aged and young people like infectious diseases. Neck pain occurs when sitting in front of the computer for a whole day; lumbago due to long-term standing in the air-conditioned room; the mouse is used too much, and the wrist is painful; occasional swimming, shoulder pain; what is coming from mountain climbing and knee pain … … people are not old, why are the muscles and bones weakened first? Experts point out that lack of exercise, incorrect posture, and athletic injuries are the leading causes of systemic "muscle and bone pain" in many young people. The muscles and joints of the whole body are also affected by six excesses of wind, cold, summer heat, dampness, dryness and fire, or by trauma and chronic strain, and the six toxicities are formed by the diseases caused by penetrating bones through the skin, which is commonly called as the bone toxicities. The bone poison exists on bones and periosteum for a long time to form the foreign poison. The toxin retention causes repeated congestion, edema, adhesion and contracture of soft tissues around bones and joints, thereby causing local blood circulation disorder, generating a large amount of acidic substances to stimulate blood vessels and damage muscle tissues, which are manifested as soreness, numbness, swelling and even red swelling and deformation of muscles, bones and joints of joints, and the serious patients can cause damage of joint sclerotin, joint deformation and incapability of self-care in life. The arthralgia and myalgia is an important clinical manifestation of the rheumatic bone disease and is treated with great importance.
At present, medicines for treating the fastening pain have various defects in the clinical treatment process, particularly western medicines have long treatment course, large side effect and no practical cure efficiency, and the aim of treating both symptoms and root causes cannot be achieved.
Disclosure of Invention
In view of the above, the present invention aims to overcome the defects of the prior art and provide a traditional Chinese medicine composition for treating arthralgia and myalgia with good curative effect, short treatment course, high cure rate and no side effect, and a method for preparing the traditional Chinese medicine composition.
In order to achieve the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine composition for treating cancer pain comprises the following components in parts by weight:
0.17 to 0.18 g of astragalus root, 0.23 to 0.24 g of clematis root, 0.14 to 0.15 g of atractylodes macrocephala koidz, 0.14 to 0.15 g of monkshood, 0.14 to 0.15 g of ephedra herb and 0.14 to 0.15 g of trogopterus dung.
Preferably, the traditional Chinese medicine composition consists of the following components in parts by weight: 0.176 g of astragalus root, 0.236 g of clematis root, 0.147 g of atractylodes, 0.147 g of Sichuan aconite root, 0.147 g of ephedra herb and 0.147 g of trogopterus dung.
Wherein, the weight components of the atractylodes macrocephala koidz, the radix aconiti, the ephedra herb and the trogopterus dung in the traditional Chinese medicine composition are the same.
The invention also provides a preparation method of the traditional Chinese medicine composition for treating fastening pain, which comprises the following steps:
taking the astragalus, the clematis root, the atractylodes rhizome, the monkshood, the ephedra herb and the trogopterus dung in parts by weight, respectively cleaning and then airing in a ventilated and cool place to obtain a mixture;
under the conditions of sterility and dust-free, the mixed material is crushed and ground into powdery mixed material;
adding rice vinegar into the powdery mixture, and uniformly stirring to obtain paste;
making pills by hand, and airing the rods at the ventilated positions.
Preferably, the weight of the rice vinegar added per gram of the mixed material is 0.735 grams.
Preferably, the particle fineness of the powdery mixed material is not less than 300 meshes.
Astragalus membranaceus, also known as astragalus membranaceus. Perennial herbs with a height of 50-100 cm. The main root is thick, woody, branched and grey-white. The stem is upright, the upper part is multi-branched, and the stem has fine edges and is white and soft. Perennial herbs with a height of 50-100 cm. The astragalus root has been used for more than 2000 years, and has the functions of enhancing the immunologic function of organisms, protecting the liver, promoting urination, resisting aging, resisting stress, reducing blood pressure and having wider antibacterial action. But excessive superficial pathogenic factors, qi stagnation and dampness obstruction, food stagnation, initial carbuncle and deep-rooted carbuncle, excessive heat-toxicity after ulceration, and yang hyperactivity of yin and liver-qi should be prohibited for patients with excessive liver-qi. Sweet in nature and slightly warm in nature. Meridian tropism means lung, spleen, liver and kidney meridians entered. Astragalus membranaceus is a pure natural product which is frequently eaten by people, and people have a smooth running of 'frequently drinking astragalus soup, preventing diseases and protecting health', which means that astragalus membranaceus is frequently used for decocting or soaking in water to replace tea for drinking, and the astragalus membranaceus has good disease prevention and health care effects. Radix astragali and ginseng both belong to good qi-tonifying drugs, and ginseng is mainly used for tonifying primordial qi and restoring yang from collapse, and is commonly used for treating acute diseases such as collapse, shock and the like with good effect. While Huang Qi is mainly tonifying deficiency, it is commonly indicated for chronic weakness, low speech and weak pulse. Some people are easy to catch cold when they meet weather change, the traditional Chinese medicine is called as 'exterior insecurity', astragalus can be used for strengthening exterior, and frequent taking of astragalus can avoid frequent cold. Modern medical research shows that astragalus has the functions of enhancing the immunity of organisms, protecting the liver, promoting urination, resisting aging, resisting stress, reducing blood pressure and resisting a wide range of bacteria. Can eliminate albuminuria caused by experimental nephritis, enhance myocardial contraction force, and regulate blood sugar content. Radix astragali can not only dilate coronary artery, improve myocardial blood supply, and enhance immunity, but also delay cell aging process. The astragalus root is convenient to eat and can be used for decocting soup, decocting paste, soaking wine, adding into dishes and the like.
Clematis chinensis, also known as Bailian root, Tiger beard and Tiebroom, is the dried root and rhizome of Clematis chinensis of Ranunculaceae. The rootstock is columnar, the length is 1.5-10 cm, and the diameter is 0.3-1.5 cm; the surface is light brown and yellow; residual stem base at the top end; the quality is tougher, and the section is fibrous; the lower side is provided with a plurality of thin roots. The root is in a slender cylindrical shape, slightly bent, 7-15 cm long and 0.1-0.3 cm in diameter; the surface is black brown, has fine longitudinal lines, has peel parts falling off, and exposes yellow white wood parts; the hard and brittle skin part is easy to break, the skin part of the fracture surface is wider, the wood part is light yellow and is slightly square, and cracks are often formed between the skin part and the wood part. The processing method comprises the following steps: removing impurities, cleaning, moistening, cutting, and drying. Nature and taste: pungent, salty and warm. The functional indications are as follows: dispel wind and dampness, dredge collaterals and alleviate pain. Can be used for treating rheumatic arthralgia, numbness of limbs, spasm of muscles and tendons, difficulty in flexion and extension, and choking throat. For pain of limbs and beriberi caused by rheumatism, it is often combined with Qiang Huo, Du Huo, niu xi and Qin jiao. For various bone sticking throat, 15g of clematis root can be singly decocted with water or added with rice vinegar decoction, and the decoction is taken after being mixed with mouth for several times and slowly swallowed. The radix Clematidis contains anemonin, anemonolactone, sterol, saccharide, saponin, lactone, phenol, and amino acid. The leaf contains lactone, phenol, triterpene, amino acid, and organic acid. Tang Ben Cao (materia Medica of Tang Dynasty): the patients with various cold diseases in the waist, kidney, feet and knees, accumulation and intestines are not healed for a long time and are taken. "Kaibao Ben Cao" (Kaibao herbal): ' Zhu Feng all wind, Xuan Tong Wu cang, remove cold stagnation in the abdomen, long-standing phlegm retention in the heart-septum, Xuan Qixuan, pus and lochiorrhea in the bladder, cold pain in the waist and knees and treating fracture. "(supplement to the Yanyi of the materia Medica): the patient is taken for pain (the upper patient 'is one who goes up and down'). "Nanjing folk herb: fresh root soaked in wine is taken to treat stomachache; mixing with white sugar, beating, and applying to the brain for a day and night to remove the skin bubbles and treat gingival swelling. "Guangxi Chinese herbal medicine": expelling wind and removing dampness, activating the channels and collaterals, promoting urination and relieving pain. It is used to treat rheumatic osteodynia, jaundice, edema, dysuria, migraine, and traumatic injury. "treat paralysis of hands and feet with pain; or injury, intolerable pain, paralysis and the like: radix Clematidis (parched) five times and two times, raw radix Aconiti and Oletum Trogopterori four times and two times respectively. It is in the form of powder, paste pill with vinegar, and large size. Seven pills are taken each time, and are added with salt soup. Tea is contraindicated. ("Puji Fang)"; the medicine is not taken for treating the waist and foot pain for a long time: clematis root five or two. Pounded and finely smashed into powder. Every day before eating, the food is adjusted by warm water, and the temperature is slightly favorable day by day. (the Chinese clematis root powder from Shenghui Fang) and prescription: washing radix Clematidis with radix Clematidis weight, soaking in wine for seven days, grinding into powder, and adding paste to make into pill, such as Firmiana simplex seed. Twenty pills are taken every time and are sent down by using medicinal liquor.
Aconitum carmichaeli Debx (Aconitum carmichaeli Debx) also named Aconitum carmichaeli Debx, Sixi Gum, Gum Poison, Dugong, Gunn Zi, Aconitum carmichaeli Debx, which is the mother root of Aconitum carmichaeli Debx belonging to Ranunculaceae, collected in late 6 to late 8 months, removed the son root, fibril and sediment, and dried in the sun. Nature and taste: pungent taste; bitter; heating; with strong toxicity, it can dispel wind, remove dampness, warm meridians, dispel cold and alleviate pain. It can be used for treating arthralgia due to wind-cold-dampness, arthralgia, numbness of limbs, hemiplegia, headache due to wind-cold evil, psychroalgia of heart and abdomen, cold hernia pain, traumatic injury, blood stasis, cellulitis, and toxic swelling, and can be used for relieving pain due to anesthesia. Generally, in the formula of the traditional Chinese medicine, the dosage of the radix aconiti cannot be too much, the dosage is preferably not more than 10g, the key point of use is long-term decoction, and the decoction is preferably more than two hours, so that the toxicity can be effectively reduced. In addition, it can be used with gan Jiang and gan Cao to reduce toxicity. For treating the pain of the patients with the inflexible pain of the course of treatment and the pain of the beriberi, 9 g of each of ephedra, peony and astragalus root, 9 g of liquorice (roasted) radix aconiti 6 g (the mouth father mouth is decocted by 400 ml of honey to obtain 200 ml of aconite), and the four mouth father mouths of the five flavors are decocted by 600 ml of water to obtain 200 ml of decoction, and residues are removed to be decocted and more decocted in honey to obtain seven unknown pain (jin Kui Yao L ü e); for the treatment of arthralgia due to wind-cold-dampness, Rong Wei and Wei do not move and pain in limbs, 100 g (peeled and cut into pieces and fried with soybean juice) of radix Aconiti Kusnezoffii 25 g (stir-fried slightly), and pounding of the above materials as fine powder and concentrated vinegar as fine powder are decocted into paste and pills, such as mung bean big, seven pills with warm wine when each dose is not counted, and Shenghui Fang (St. Shenghui Fang); for wind-cold-dampness arthralgia with spasm pain, 100 g of trogopterus dung, monkshood (peeled off and scalded monkshood and navel) and rhizoma atractylodis (soaked and dried in thin-cut wine), 50 g of native copper (cooked), fine powder on the Chinese medicinal materials, and water paste into pills, such as phoenix tree seed big, seven pills for each dose, and the pills are gradually added under the condition of warm wine for several doses to cure the disease (Wu shu pill from Puji Fang)
The herba Ephedrae is a herb recorded in Chinese pharmacopoeia, and the medicinal source is dry grass stem of Gnetum plant Ephedra sinica Stapf, Ephedra sinica Stapf or Ephedra equiseti. In autumn, green grass stems are harvested and dried in the sun. It has warm nature, pungent and slightly bitter taste, has effects of inducing sweat, dispelling cold, dispersing lung qi, relieving asthma, inducing diuresis, and relieving swelling, and can be used for treating wind-cold type common cold, chest distress, cough, and edema, and bronchial asthma. The alias is Ephedra sinica Stapf, Ephedra of Ephedraceae, with a height of 20-40 cm; the wood stem is short or creeping. Three Ephedra plants, Ephedra sinica (Ephedra sinica), Ephedra equiseti (Ephedra equisetina) and Ephedra intermedia (Ephedra intermedia), are herbaceous shrubs, and the adopted part is a herbaceous stem, which is also an important medicinal plant. The alkaloid is rich in alkaloid, and is the main resource for extracting ephedrine. The wood stems are few, and the processing and refining are easy; it is usually in plain, hillside, riverbed and grassland, so it is easy to collect, and it should not be used or used with cautions for the mild syndrome of wind-cold, palpitation, insomnia, cough and asthma due to lung deficiency because of its strong sweating ability. Ma Huang Ma Rou is suitable for the elderly, weak people and children. The Chinese herbs in the recipe disperse wind-cold (the taste and color are named as Ben Cao gang mu, which states that the recipe is numb and yellow). It is used for treating exterior excess syndrome due to wind-cold. It is pungent and pungent with the actions of dispersing, warm in nature and dispelling cold, and good at opening striae and striae to induce sweat, so it is a strong herb with pungent and warm natures for relieving exterior syndrome. For exterior syndrome of wind-cold type manifested by aversion to cold, fever, headache, body pain, anhidrosis and superficial and tense pulse due to external wind-cold and closed striae, it is often combined with Gui Zhi to reinforce the action of relieving exterior syndrome and dispelling cold, such as Ma Huang Tang (treatise on Cold-induced disease). Shen nong Ben Cao Jing (Shen nong's herbal) states that stroke, typhoid, headache and warm malaria are the main causes. Relieving exterior syndrome and sweating, eliminating pathogenic heat, relieving cough and adverse rising of qi, removing cold and heat, and resolving hard mass. The famous medical records indicate that the traditional Chinese medicine can open the striae and relieve the muscles. The compendium of materia Medica, Ma Huang is a special herb for lung meridian, so it is indicated for lung diseases. Zhang Zhongjing for typhoid fever, Ma Huang for no sweating, Gui Zhi for sweating. The ephedra volatile oil has the function of sweating, and the ephedrine can increase the secretion of sweat glands of a person in a high-temperature environment and increase the speed. The herba Ephedrae volatile oil emulsion has antipyretic effect. Ephedrine and pseudoephedrine both have effects of relieving spasm of bronchial smooth muscle. The pseudoephedrine has obvious diuretic effect. Ephedrine can excite heart, contract blood vessel, and increase blood pressure; has obvious exciting effect on central nerve, and can cause excitation, insomnia and uneasiness. The volatile oil has effect in inhibiting influenza virus. The methanol extract has antiinflammatory effect. The decoction has the function of resisting pathogenic microorganisms. The alkaloids can excite heart, contract blood vessel, and increase blood pressure; has obvious exciting effect on central nerve, and can cause excitation, insomnia and uneasiness. The volatile oil has effect in inhibiting influenza virus. The methanol extract has antiinflammatory effect. The decoction has the function of resisting pathogenic microorganisms.
Oletum Trogopterori (Faeces Trogopterori) is also known as medicinal material, Faeces Laevigatae, and Oletum Trogopterori, and is divided into two kinds of Oletum Trogopterori rice and Oletum Trogopterori block (blood Oletum Trogopterori and sugar Oletum Trogopterori). The Lingzhi rice is the dry excrement of compound-tooth squirrel, and the Lingzhi blocks are the mixture of excrement and urine mixed with small amount of sandstone for drying and coagulation. Can be used for treating hemorrhage due to blood stasis, such as metrorrhagia, metrostaxis, and stabbing pain of lower abdomen. It can be stir-baked and ground into powder alone and taken with warm wine, or used in combination with other medicines. The trogopterus dung has obvious effect of inhibiting the growth of tubercle bacillus in a test tube, and the trogopterus dung water-soaking agent (1:2) has different degrees of inhibiting effects on trichophyton violaceum, trichophyton concentricum, trichophyton schoenliensis, trichophyton ozi, trichophyton ferrugineum, trichophyton lanugineum, trichophyton gypseum, epidermophyton grophytes inguinale, epidermophyton rubrum, chefmann-wolff epidermophyton, nocardia stellata and other skin pathogenic fungi in the test tube, namely smell is sweet, warm and nontoxic. Dislike ginseng, it can damage people. The indications are cold heart and abdomen, infantile malnutrition, epidemic prevention, intestinal wind, qi and blood circulation promotion and female blood block (Kaibao). Treat cold accumulation in wounds (Susong). It is usually stir-baked half and half into powder for profuse metrorrhagia, and can promote blood circulation to stop bleeding when taken with wine. It is used to treat abdominal pain due to blood-qi stagnation, hernia pain, dysentery with bloody stool, intestinal wind, abdominal pain, blood arthralgia, liver malaria, fever, regurgitation, diabetes, phlegm and saliva with blood in nest, blood passing pupil, blood coagulation, toothache, heavy tongue, infantile convulsion, epilepsy, and snake, scorpion, and centipede wound (Shizhen). The preparation method comprises the following steps: parching Oletum Trogopterori in pan, spraying rice vinegar, parching to slightly dry, taking out when the surface is slightly glossy, and air drying. For example, Lingzhi blocks should be cut into small blocks (1.5 jin of vinegar per 10 jin).
The invention has the beneficial effects that:
(1) the pill is prepared from 6 Chinese herbal medicines, and is based on the theory of syndrome differentiation and treatment of traditional Chinese medicine, and is based on the effects of regulating qi and activating blood circulation, and assisting in expelling wind and removing cold, tonifying deficiency and warming yang, so that the purpose of treating arthralgia and myalgia is finally achieved, wherein the astragalus membranaceus protects the liver and promotes diuresis; radix Clematidis has effects of dispelling pathogenic wind, removing dampness, dredging collaterals, relieving pain, eliminating phlegm and water, and removing stagnation; cang Zhu dampness eliminating, spleen strengthening, wind expelling, and cold expelling; radix Aconiti has effects of dispelling pathogenic wind, removing dampness, warming channels and relieving pain; ephedra stem can induce sweat to release exterior, promote the dispersing function of the lung, relieve asthma, induce diuresis to alleviate edema; oletum Trogopterori has effects of promoting blood circulation, removing blood stasis, resolving food stagnation and eliminating phlegm. The six Chinese herbal medicines are mutually compatible, and finally the purposes of removing dampness and dispelling cold, regulating qi and promoting blood circulation are achieved.
(2) The invention grinds each raw material into powder, and adds vinegar to modulate, utilizes the methods of micro ecology and bionics, through the way of biological grafting, simulates the intestinal environment of human body and the digestion and decomposition process of traditional Chinese medicine components in human body in vitro, carries on biological transformation to the extracted traditional Chinese medicine effective components, transforms the macromolecule substance of traditional Chinese medicine into small molecule components which can be absorbed directly by the intestinal tract of human body through microorganism, the 6 kinds of Chinese herbal medicine which are predigested and transformed not only completely remove the harmful toxicity of each medicine, but also the formed medicament has quantitative curative effect, and can be absorbed by human body rapidly, the drug effect is improved by 6-22 times compared with traditional Chinese medicine.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
Example 1
A traditional Chinese medicine composition for treating arthralgia and myalgia comprises the following raw materials in parts by weight:
0.176 g of astragalus root, 0.236 g of clematis root, 0.147 g of atractylodes, 0.147 g of Sichuan aconite root, 0.147 g of ephedra herb and 0.147 g of trogopterus dung.
The preparation method of the traditional Chinese medicine composition comprises the following steps:
(1) preparing monkshood root: soaking and bleaching fresh radix Aconiti with cold water, changing water for 2 times every day, taking out when the radix Aconiti is slightly spicy, decocting together with Glycyrrhrizae radix and semen Sojae Atricolor at a weight ratio of 20:1:2 with water until there is no white core in radix Aconiti, removing Glycyrrhrizae radix and semen Sojae Atricolor, air drying, moistening until the water content is 5 wt%, and slicing.
(2) Taking the astragalus, the clematis root, the atractylodes rhizome, the ephedra herb and the trogopterus dung in parts by weight, respectively cleaning, then airing in a ventilated and cool place to obtain a mixture, then adding a certain amount of radix aconiti, and uniformly mixing;
(3) under the aseptic and dustless conditions, the six mixed materials are crushed and ground into powdery mixed materials to obtain mixed powder with the particle fineness of 300 meshes; the mixed materials can be pulverized by adopting an ultramicro pulverizing technology, ultrasonic pulverization is carried out, the central particle size of the crude drug is below 10 mu m and below 6 mu m, the cell wall breaking rate is above 95%, effective components in the crude drug are directly exposed, and the dissolution and the effect taking of the components of the crude drug are quicker and more complete.
(4) Adding rice vinegar into the powdery mixture, and uniformly stirring to obtain paste, wherein the amount of the rice vinegar is 0.735 g, and the degree of the rice vinegar is between 6 and 10 degrees;
(5) manually kneading into round pills with the size of soybean, screening out pills with uniform size by using a sieve again, airing the rods at a ventilation position, and drying in the sun to ensure that the drug effect is not lost, weighing at last, and packaging into bags with different treatment courses according to different weights to be convenient for patients to use. Or making into ointment or patch, and applying or sticking on affected part. It is administered twice a day, 4-6 pills each time, or in combination with patch.
Contraindications are as follows: the medicine can not be taken with radix Ginseng and Mel.
Example 2
A traditional Chinese medicine composition for treating arthralgia and myalgia comprises the following raw materials in parts by weight:
1.74 g of astragalus root, 2.34 g of clematis root, 1.48 g of atractylodes, 1.48 g of Sichuan aconite root, 1.48 g of Chinese ephedra and 1.48 g of trogopterus dung.
(1) Preparing monkshood root: soaking and bleaching fresh radix Aconiti with cold water, changing water for 2 times every day, taking out when the radix Aconiti is slightly spicy, decocting together with Glycyrrhrizae radix and semen Sojae Atricolor at a weight ratio of 20:1:2 with water until there is no white core in radix Aconiti, removing Glycyrrhrizae radix and semen Sojae Atricolor, air drying, moistening until the water content is 5 wt%, and slicing.
(2) Taking the astragalus, the clematis root, the atractylodes rhizome, the ephedra herb and the trogopterus dung in parts by weight, respectively cleaning, then airing in a ventilated and cool place to obtain a mixture, then adding a certain amount of radix aconiti, and uniformly mixing;
(3) under the aseptic and dustless conditions, the six mixed materials are crushed and ground into powdery mixed materials to obtain mixed powder with the particle fineness of 300 meshes; the mixed materials can be pulverized by adopting an ultramicro pulverizing technology, ultrasonic pulverization is carried out, the central particle size of the crude drug is below 10 mu m and below 6 mu m, the cell wall breaking rate is above 95%, effective components in the crude drug are directly exposed, and the dissolution and the effect taking of the components of the crude drug are quicker and more complete.
(4) Adding rice vinegar into the powdery mixture, and uniformly stirring to obtain paste, wherein the amount of the rice vinegar is 7.36 g, and the degree of the rice vinegar is 6-10 degrees;
(5) the pills are manually pinched into round pills, the pills with uniform sizes are screened out by using the sieve again, the airing rod is arranged at the ventilation position and cannot be exposed, the drug effect is ensured not to be lost, and the pills are weighed finally and packed into bags with different treatment courses according to different weights to be convenient for patients to use. It is administered twice a day, 4-6 pills each time, or in combination with patch.
Contraindications are as follows: the medicine can not be taken with radix Ginseng and Mel.
The following uses the Chinese herbal medicine composition obtained in example 2 to further illustrate the beneficial effects of the Chinese herbal medicine of the present invention through clinical case statistics.
The clinical cases comprise 168 cases, each half of men and women, the age of 40-55 years and the average age of 47 years, wherein the cases comprise patients with aching pain, numbness, difficult flexion and extension of neck, shoulders, waist and legs, joints and bones and muscles, and the like caused by hyperosteogeny, rheumatism, rheumatoid arthritis, lumbar muscle strain, cervical spondylosis, scapulohumeral periarthritis and the like.
1. Observation of pain
(1) Assessment of pain
No pain 0, severe pain 100;
(2) intensity of pain
0-no pain; 1-mild discomfort; 2-discomfort; 3-difficulty in handling; 4-feared pain; 5-extreme pain;
2. criteria for therapeutic effect
The effect is shown: the pain integral value after treatment is reduced by more than or equal to 70 percent compared with the integral value before treatment.
The method has the following advantages: the pain integral value after treatment is reduced by more than or equal to 30 percent and less than 70 percent compared with the integral value before treatment.
And (4) invalidation: the post-treatment pain integrated value was < 30% lower than the pre-treatment integrated value.
Note: calculation formula (nimodipine method): [ (integration before treatment-integration after treatment) ÷ integration before treatment ] × 100%.
3. Therapeutic results
The traditional Chinese medicine composition is used for treating 168 cancer pains, wherein 86 cases of obvious effects, 67 cases of effective effects and 15 cases of ineffective effects are achieved, the total effective rate reaches 91.07%, the treated effective patients are all called that the traditional Chinese medicine composition can relieve pain within 30 minutes of medication, dependence and addiction of other commonly taken analgesics such as non-opioid analgesics or opioid analgesics are not generated, and the pain effect is obviously reduced after the traditional Chinese medicine composition is continuously used for 10-20 days.
Example of the case 1: acute lumbar sprain
Certain Liu is 45 years old for men, and fixed counties in Henan province, drivers of large cars and 2009 people are supported by three people in the same year for 8 months, the waist movement is limited, the waist pressure pain is obvious, the pain is sensed immediately by touch, and the patients refuse to receive massage physiotherapy.
Example of the case 2: old fracture
A patient goes upstairs to fetch the object in 5 months of 2010, falls into injury carelessly, is difficult to endure, cannot move a right wrist joint and an elbow joint, and is diagnosed as ulna central fracture and fracture of a distal head of a disturbed bone, namely fractured ulna and radius double-shaped fracture through an X-ray of an orthopedics hospital. Fixed by gypsum, the traditional Chinese medicine is used for treating for two months, and the picture is not improved after being rechecked. In 2011, the treatment is performed on my place in 1 month, the right elbow joint is examined, and the pain and swelling of the wrist joint are not eliminated. The pain is severe during the activity, the tenderness is obvious, the sequelae of old ulna and radius fracture injury are diagnosed, the treatment method is that the bone setting technique is wound around the bone setting position, then the pill and the application of the invention are applied, the elbow joint and the wrist joint are stopped, the three-ply board is adopted for fixation, and the bandage is tightened by external application. After 10 days, the dressing change is rechecked, the swelling disappears, the elbow and wrist joints stretch and recover the activity, the method that the second course is the same as the first course is followed, after 8 days, the splint and the plaster are removed, and after X-ray rechecking, all the patients can be normally cured and are visited for a plurality of times, and no symptom of recurrent pain is seen.
Example of the case 3: lumbar disc herniation, sciatica.
Zheng a certain woman, 48 years old, Luodahe city in Henan province, had rheumatic arthritis for more than twenty years, often occurred with mistakes, each episode of the disease was febrile, each major joint was red, swollen and painful, then was hospitalized for four times, and then was treated for six months by massage, and the effect was not obvious. After the physician asks for the fact, the swelling of each large joint is found, the hot compress is carried out on each joint by the hot compress pill, the pills are taken for one month, the swelling is eliminated, the life can be automatically regulated, the medicine is continuously taken for twenty treatment courses, four years of follow-up visit are realized, people feel uncomfortable even if weather changes occur, but no obvious pain exists, the redness and swelling of each joint do not occur, and the work can be recovered.
Will be appreciated that: rheumatoid arthritis belongs to the field of medical paralysis, and the sound production of arthralgia syndrome is caused by the fact that sweat pores are open and weak, the nutrient and defensive qi is not fixed, and wind-cold-dampness pathogen invades due to deficiency, so that vital qi is blocked by pathogen and cannot be diffused, and the rheumatoid arthritis is remained for a long time to cause diseases. The traditional Chinese medicine composition has reasonable formula, has the effects of dispelling wind and clearing heat, promoting blood circulation and removing blood stasis, combating poison with poison, relieving distension and fullness and dissipating stagnation, and dispelling paralysis, and achieves the purpose of treatment.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims (6)

1. The traditional Chinese medicine composition for treating cancer pain is characterized in that each gram of the traditional Chinese medicine composition is composed of the following components in parts by weight: 0.17 to 0.18 g of astragalus root, 0.23 to 0.24 g of clematis root, 0.14 to 0.15 g of atractylodes macrocephala koidz, 0.14 to 0.15 g of monkshood, 0.14 to 0.15 g of ephedra herb and 0.14 to 0.15 g of trogopterus dung.
2. The traditional Chinese medicine composition according to claim 1, wherein each gram of the traditional Chinese medicine composition comprises the following components in parts by weight: 0.176 g of astragalus root, 0.236 g of clematis root, 0.147 g of atractylodes, 0.147 g of Sichuan aconite root, 0.147 g of ephedra herb and 0.147 g of trogopterus dung.
3. The Chinese medicinal composition according to claim 1 or 2, wherein the weight components of atractylodes macrocephala koidz, monkshood, ephedra herb and trogopterus dung in the Chinese medicinal composition are the same.
4. A method for preparing the traditional Chinese medicine composition of any one of claims 1 to 3, comprising the following steps:
taking the astragalus, the clematis root, the atractylodes rhizome, the monkshood, the ephedra herb and the trogopterus dung in parts by weight, respectively cleaning and then airing in a ventilated and cool place to obtain a mixture;
under the conditions of sterility and dust-free, the mixed material is crushed and ground into powdery mixed material;
adding rice vinegar into the powdery mixture, and uniformly stirring to obtain paste;
making into pill or ointment by hand, and airing the rod at the ventilation position.
5. The method according to claim 4, wherein the rice vinegar is added in an amount of 0.735 g per one g of the mixture.
6. The method according to claim 4, wherein the particle fineness of the powdery mixture is not less than 300 mesh.
CN201811310990.3A 2018-11-05 2018-11-05 Traditional Chinese medicine composition for treating arthralgia and myalgia and method Pending CN111202774A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811310990.3A CN111202774A (en) 2018-11-05 2018-11-05 Traditional Chinese medicine composition for treating arthralgia and myalgia and method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811310990.3A CN111202774A (en) 2018-11-05 2018-11-05 Traditional Chinese medicine composition for treating arthralgia and myalgia and method

Publications (1)

Publication Number Publication Date
CN111202774A true CN111202774A (en) 2020-05-29

Family

ID=70780084

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811310990.3A Pending CN111202774A (en) 2018-11-05 2018-11-05 Traditional Chinese medicine composition for treating arthralgia and myalgia and method

Country Status (1)

Country Link
CN (1) CN111202774A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101239171A (en) * 2008-03-12 2008-08-13 贺元甲 Viscera muscles and bones pain-eliminate plaster and preparation thereof
CN101856425A (en) * 2010-06-04 2010-10-13 王和鸣 Externally applied medicine for alleviating cancer pain and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101239171A (en) * 2008-03-12 2008-08-13 贺元甲 Viscera muscles and bones pain-eliminate plaster and preparation thereof
CN101856425A (en) * 2010-06-04 2010-10-13 王和鸣 Externally applied medicine for alleviating cancer pain and preparation method thereof

Similar Documents

Publication Publication Date Title
CN103656238B (en) A kind of Chinese medicine composition for the treatment of rheumatic osteopathia
CN102119989B (en) Traditional Chinese medicine capsule for treating lumbar intervertebral disc protrusion, hyperosteogeny, periarthritis humeroscapularis, arthritis and cervical spondylosis
CN101167999B (en) Hot compress exergy and preparation method thereof
CN102008674B (en) Plaster for treating herniated disk, hyperosteogeny and rheumatoid diseases and preparation method thereof
CN112494606A (en) Traditional Chinese medicine composition for treating arthralgia, myalgia and rheumatic pain and preparation method and application thereof
CN105709074A (en) Medicine for treating rheumatic arthritis and hyperostosis and preparation method
CN106039174A (en) Traditional Chinese medicinal liquor for treating osteoarthrosis
CN102284056B (en) Chinese medicinal pill for treating cervical spondylosis
CN104435587A (en) Traditional Chinese medicinal herb ointment for performing aided acupuncture and moxibustion therapy on arthralgia and myalgia and preparation method of ointment
CN111202774A (en) Traditional Chinese medicine composition for treating arthralgia and myalgia and method
CN104042872B (en) Traditional Chinese medicine composition for treating common cold of children and preparation method thereof
CN115645503B (en) Medicinal composition and acupoint application paste for treating chronic pain diseases
CN101095753A (en) Chinese medicine preparation for treating diabetic hyperlipaemia
CN106729256A (en) It is a kind of to treat lavipeditum powder of arthralgia pain due to rheumatism and preparation method thereof
CN106729443A (en) A kind of Chinese medicine composition for swelling and pain relieving and preparation method thereof
CN105362554A (en) Traditional Chinese medicine for treating poliomyelitis due to liver-kidney deficiency
CN105412825A (en) Drug for treating hyperlipidaemia and preparation method thereof
CN104042924A (en) Chinese herba preparation capable of treating qi and blood deficiency osteoarthritis and preparation method thereof
CN104645061A (en) Medicine for treating blood stasis stationary chronic gastric ulcer and preparation method
CN104474157A (en) Traditional Chinese medicine for treating painful heel caused by phlegm-accumulation stasis
CN103920122B (en) A kind of Chinese medicine preparation for treating gastroenteritis and preparation method
CN104173646A (en) Traditional Chinese medicine decoction for treating dizziness caused by qi-blood deficiency and preparation method thereof
CN102688391B (en) Traditional Chinese medicine (TCM) liquor for treating osteoporosis
CN103623096A (en) Reconstruction pill for treating hemiplegia and restoring consciousness and preparation method thereof
CN113925916A (en) Chinese herbal medicine preparation cassia twig heart nourishing soup or pill

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20200529