CN111166289B - Remote endocrine disorder detection equipment - Google Patents
Remote endocrine disorder detection equipment Download PDFInfo
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- CN111166289B CN111166289B CN202010007492.2A CN202010007492A CN111166289B CN 111166289 B CN111166289 B CN 111166289B CN 202010007492 A CN202010007492 A CN 202010007492A CN 111166289 B CN111166289 B CN 111166289B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
- A61B5/4222—Evaluating particular parts, e.g. particular organs
- A61B5/4227—Evaluating particular parts, e.g. particular organs endocrine glands, i.e. thyroid, adrenals, hypothalamic, pituitary
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
Abstract
The invention relates to a remote endocrine disorder detection device. The remote sex hormone detection equipment is established, and the required characteristics of the remote equipment are combined, and the enzyme linked immunosorbent assay is used for detecting the sex hormone 6, so that the setting cost of the equipment is reduced. When sex hormone is detected, an electrochemical blood sugar sensor is used for detecting the blood sugar content, and the detected blood sugar content is used for quantitatively calibrating the detection result of 6 sex hormones, so that the reduction of the detection precision of an enzyme-linked immunosorbent assay caused by the use environment of a terminal is avoided; still set up special remote communication function, all had corresponding counter-measure to various needs, diversified communication mode can be fine guarantees user's privacy, and can also make things convenient for the crowd who does not have mobile terminal to use.
Description
Technical Field
The invention relates to the field of endocrine detection, in particular to remote endocrine disorder detection equipment.
Background
Endocrine disorders, i.e. endocrine dysregulation. The human body has an endocrine system, and various hormones are secreted to regulate the metabolism and physiological functions of the human body together with the nervous system. The hormones are normally in balance. If the balance is broken for some reason (too much or too little hormone), endocrine disturbance is caused, and corresponding clinical manifestations are caused. Endocrine disorders may occur in both men and women. The endocrine disorders most likely to occur in women are endocrine disorders, resulting in dysphoria, delayed menstruation, etc.
The existing detection mode for female endocrine dyscrasia is generally to go to a hospital for sex hormone level detection, but the time cost and the manager cost for going to the hospital are high. However, the current remote medical devices are generally limited to relatively simple indicators that can detect the blood glucose of the user. If high-precision detection equipment is adopted for detecting sex hormone, the components are too high, so that a user cannot bear the sex hormone detection method, and the user does not need to purchase equipment specially aiming at the endocrine dyscrasia due to the sporadic nature of the endocrine dyscrasia. If only test paper is used for detecting endocrine, on one hand, a user has no analysis capability, and on the other hand, the user is not convenient to draw blood by himself during blood detection.
Disclosure of Invention
Aiming at the content, the remote endocrine disorder detection equipment is provided for solving the problems and comprises a remote host, a remote analysis module, a terminal detector, a terminal interaction module and a mobile equipment terminal; the remote host is connected with the remote analysis module, the terminal detector, the terminal interaction module and the mobile equipment terminal, and the terminal detector is connected with the terminal interaction module and the mobile equipment terminal; the remote analysis module is connected with the terminal interaction module and the mobile equipment terminal;
the terminal detector is used for detecting the sex hormone level and is provided with a main controller, a recording device, a display device, an electrochemical blood glucose sensor and an enzyme-linked immunosorbent detector; the main controller is connected with the recording equipment, the display equipment, the electrochemical blood sugar sensor and the enzyme-linked immunosorbent assay detector; the display device is used for displaying questions to be answered by a user during detection, and the recording device is used for recording voice of the user;
the electrochemical blood sugar sensor is used for detecting the blood sugar content; the enzyme-linked immune hormone detector comprises a detector and a hormone detection test paper; the test paper comprises 7 detection lines and 1 quality control line; the detector comprises a test paper slot and 8 detection heads corresponding to detection lines and quality control lines on the test paper;
the terminal detector sends the detected 6 sex hormone levels and the recorded voice to the remote host; the terminal interaction module and the mobile equipment terminal are used for the user to carry out voice and video communication with the doctor; the remote analysis module is used for displaying the sex hormone 6 level and playing the recorded voice, and providing the doctor with the voice and video communication.
The terminal detector and the terminal interaction module are integrally arranged, and the terminal interaction module is provided with a terminal display screen, an earphone, a microphone and a high-definition camera; the mobile equipment terminal is a mobile phone or a tablet computer.
The electrochemical blood glucose sensor is internally provided with an electrochemical blood glucose monitoring module and a sample preparation module, and is used for carrying out electrochemical monitoring on a blood sample of a blood sample, preparing the blood sample into serum and loading the serum on hormone detection test paper;
the hormone detection test paper is provided with an enzyme-linked immunosorbent assay line for detecting six items of follicle-stimulating hormone (FSH), luteinizing Hormone (LH), estradiol E2, progesterone P, testosterone T and Prolactin (PRL), a quality control line for detecting whether the test paper is normal and a detection line for detecting the blood sugar content based on enzyme-linked immunosorbent assay;
when the hormone detection test paper is inserted into the test paper slot, a light emitting head and a light receiving head are arranged above each detection line and each quality control line; the light emitting head provides illumination with fixed intensity, and the light receiving head is used for detecting the brightness of the detection line or the quality control line corresponding to the wavelength;
the terminal detector sends the collected blood glucose concentration detected by the electrochemical blood glucose sensor and the brightness detected by the 8 light-receiving heads to the remote host.
The remote host is stored with 6 sex hormones and the corresponding ELISA working curve of blood sugar, the remote host calibrates the brightness of the blood sugar detected by the corresponding light receiving head according to the blood sugar concentration detected by the electrochemical blood sugar sensor, and then quantitatively calculates the index of the 6 sex hormones according to the calibrated blood sugar concentration, thereby eliminating the ELISA error caused by the environment and equipment error.
The remote host sends the indexes of 6 sex hormones and the voice recorded in the detection of the terminal detector to the remote analysis module, and the remote analysis module collects the analysis result of the doctor on the indexes of 6 sex hormones in the remote analysis module and sends the analysis result to the mobile equipment terminal.
The terminal interaction module and the mobile equipment terminal are used for establishing video call connection with the remote analysis module when a doctor needs to communicate with a detector in a face-to-face mode.
The invention has the beneficial effects that:
the invention establishes remote sex hormone six-item detection equipment, and combines the required characteristics of the remote equipment, and uses the enzyme linked immunosorbent assay to detect the sex hormone 6 items, thereby reducing the setting cost of the equipment. When sex hormone is detected, an electrochemical blood sugar sensor is used for detecting the blood sugar content, and the detected blood sugar content is used for quantitatively calibrating the detection result of the sex hormone 6 items, so that the reduction of the detection precision of an enzyme-linked immunosorbent assay caused by the use environment of a terminal is avoided;
the invention also sets special remote communication function, has corresponding counter measures for various needs, and can directly send the detection result to the mobile phone of the user when the detection result of the user is normal; when the user detection result is slightly abnormal but the face-to-face communication is not needed, the notice can be directly sent to the mobile phone of the user; therefore, medical resources can be greatly saved, and the use by users is convenient. When the detection result of the user is abnormal and needs to be further communicated, the doctor can communicate with the user through the terminal interaction module or the mobile terminal of the user to further determine the state of an illness, the privacy of the user can be well guaranteed through various communication modes, and the doctor can conveniently use the doctor by people without the mobile terminal.
Drawings
The accompanying drawings, which are included to provide a further understanding of the disclosed subject matter, are incorporated in and constitute a part of this specification. The drawings illustrate the implementations of the disclosed subject matter and, together with the detailed description, serve to explain the principles of implementations of the disclosed subject matter. No attempt is made to show structural details of the disclosed subject matter in more detail than is necessary for a fundamental understanding of the disclosed subject matter and various modes of practicing the same.
FIG. 1 is a connection diagram of the overall structure of the present invention;
FIG. 2 is a schematic view of the internal connection of the terminal detector of the present invention;
FIG. 3 is a schematic diagram of an ELISA detector of the present invention.
Detailed Description
The advantages, features and methods of accomplishing the same will become apparent from the drawings and the detailed description that follows.
Example 1:
a remote endocrine disorder detection device comprises a remote host, a remote analysis module, a terminal detector, a terminal interaction module and a mobile device terminal; the remote host is connected with the remote analysis module, the terminal detector, the terminal interaction module and the mobile equipment terminal, and the terminal detector is connected with the terminal interaction module and the mobile equipment terminal; the remote analysis module is connected with the terminal interaction module and the mobile equipment terminal;
the terminal detector is used for detecting the sex hormone level and is provided with a main controller, a recording device, a display device, an electrochemical blood glucose sensor and an enzyme-linked immunosorbent detector 1; the main controller is connected with the recording equipment, the display equipment, the electrochemical blood sugar sensor and the enzyme-linked immunosorbent hormone detector 1; the display device is used for displaying questions to be answered by a user during detection, and the recording device is used for recording voice of the user;
the electrochemical blood sugar sensor is used for detecting the blood sugar content; the enzyme-linked sex hormone detector 1 comprises a detector and a hormone detection test paper 2; the detection test paper 2 comprises 7 detection lines and 1 quality control line; the detector comprises a test paper slot and 8 detection heads corresponding to detection lines and quality control lines on the test paper;
the terminal detector sends the detected 6 sex hormone levels and the recorded voice to the remote host; the terminal interaction module and the mobile equipment terminal are used for the user to carry out voice and video communication with the doctor; the remote analysis module is used for displaying the sex hormone 6 level and playing the recorded voice, and providing the doctor with the voice and video communication.
The terminal detector and the terminal interaction module are integrally arranged, and the terminal interaction module is provided with a terminal display screen, an earphone, a microphone and a high-definition camera; the mobile equipment terminal is a mobile phone or a tablet computer.
An electrochemical blood glucose monitoring module and a sample preparation module are arranged in the electrochemical blood glucose sensor and are used for carrying out electrochemical monitoring on a blood sample of a blood sample, and the blood sample is prepared into serum and loaded on the hormone detection test paper 2;
the hormone detection test paper 2 is provided with an enzyme-linked immunosorbent assay line for detecting six items of follicle-stimulating hormone (FSH), luteinizing Hormone (LH), estradiol E2, progesterone P, testosterone T and Prolactin (PRL), a quality control line for detecting whether the test paper 2 is normal and a detection line for detecting the blood sugar content based on enzyme-linked immunosorbent assay;
when the hormone detection test paper 2 is inserted into the test paper slot, a light emitting head 3 and a light receiving head 4 are arranged above each detection line and each quality control line; the light emitting head 3 provides illumination with fixed intensity, and the light receiving head 4 is used for detecting the brightness of the detection line or the quality control line corresponding to the wavelength;
the terminal detector sends the collected blood glucose concentration detected by the electrochemical blood glucose sensor and the brightness detected by the 8 light-receiving heads to the remote host.
The remote host is stored with 6 sex hormones and the corresponding ELISA working curve of blood sugar, the remote host calibrates the brightness of the blood sugar detected by the corresponding light receiving head according to the blood sugar concentration detected by the electrochemical blood sugar sensor, and then quantitatively calculates the index of the 6 sex hormones according to the calibrated blood sugar concentration, thereby eliminating the ELISA error caused by the environment and equipment error.
The remote host sends the indexes of 6 sex hormones and the voice recorded in the detection of the terminal detector to the remote analysis module, and the remote analysis module collects the analysis result of the doctor on the indexes of 6 sex hormones in the remote analysis module and sends the analysis result to the mobile equipment terminal.
The terminal interaction module and the mobile equipment terminal are used for establishing video call connection with the remote analysis module when a doctor needs to communicate with a detector in a face-to-face mode.
Example 2: this example illustrates the manner of use of the device of the present invention.
When in use, a patient firstly goes to a department provided with a terminal detector for detection, and the terminal detector can be arranged in a drugstore, a small clinic and even a community activity center; then the user lets a nurse or other staff draw blood, and the drawn blood is used for carrying out the electrochemical detection of the blood sugar; after the detection is finished, preparing blood samples into serum, and loading the serum on test paper;
then, analyzing the test paper by using an enzyme-linked immunosorbent assay detector, and sending an analysis result to a remote host; when the detection is carried out, the display device of the terminal detector displays the questions to be answered by the user, and the user can record the sound through the sound recording module. The recordings are sent to the remote host together.
When sex hormone is detected, an electrochemical blood sugar sensor is used for detecting the blood sugar content, so that the detected blood sugar content is used for quantitatively calibrating the detection result of the sex hormone 6, and the reduction of the detection precision of an enzyme-linked immunosorbent assay caused by the use environment of a terminal is avoided;
the doctor analyzes the illness state of the patient through the remote analysis module, and when the detection result of the user is normal, the detection result can be directly sent to the mobile phone of the user; when the user detection result is slightly abnormal but the face-to-face communication is not needed, the notice can be directly sent to the mobile phone of the user; therefore, medical resources can be greatly saved, and the use by users is convenient. When the detection result of the user is abnormal and needs to be further communicated, the doctor can communicate with the user through the terminal interaction module or the mobile terminal of the user to further determine the state of an illness, the privacy of the user can be well guaranteed through various communication modes, and the doctor can conveniently use the doctor by people without the mobile terminal.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (3)
1. A remote endocrine disorder detection device comprises a remote host, a remote analysis module, a terminal detector, a terminal interaction module and a mobile device terminal; the method is characterized in that:
the remote host is connected with the remote analysis module, the terminal detector, the terminal interaction module and the mobile equipment terminal, and the terminal detector is connected with the terminal interaction module and the mobile equipment terminal; the remote analysis module is connected with the terminal interaction module and the mobile equipment terminal;
the terminal detector is used for detecting the sex hormone level and is provided with a main controller, a recording device, a display device, an electrochemical blood glucose sensor and an enzyme-linked immunosorbent assay detector (1); the main controller is connected with a recording device, a display device, an electrochemical blood sugar sensor and an enzyme-linked immunosorbent assay instrument (1); the display device is used for displaying questions to be answered by a user during detection, and the recording device is used for recording voice of the user;
the electrochemical blood sugar sensor is used for detecting the blood sugar content; the enzyme-linked immune hormone detector (1) comprises a detector and a hormone detection test paper (2); the detection test paper (2) comprises 7 detection lines and 1 quality control line; the detector comprises a test paper slot and 8 detection heads corresponding to a detection line and a quality control line on the test paper;
the terminal detector sends the detected 6 sex hormone levels and the recorded voice to the remote host; the terminal interaction module and the mobile equipment terminal are used for the user to carry out voice and video communication with the doctor; the remote analysis module is used for displaying the level of 6 sex hormones and playing recorded voice for doctors to perform voice and video communication;
an electrochemical blood glucose monitoring module and a sample preparation module are arranged in the electrochemical blood glucose sensor and are used for carrying out electrochemical monitoring on a blood sample of a blood sample, and the blood sample is prepared into serum and loaded onto the hormone detection test paper (2);
the hormone detection test paper (2) is provided with an enzyme-linked immunosorbent assay line for detecting six items of follicle-stimulating hormone (FSH), luteinizing Hormone (LH), estradiol (E2), progesterone (P), testosterone (T) and Prolactin (PRL), a quality control line for detecting whether the test paper (2) is normal and a detection line for detecting the blood sugar content based on enzyme-linked immunosorbent assay;
when the hormone detection test paper (2) is inserted into the test paper slot, a light-emitting head (3) and a light-receiving head (4) are arranged above each detection line and each quality control line; the light emitting head (3) provides illumination with fixed intensity, and the light receiving head (4) is used for detecting the brightness of light with the wavelength corresponding to the detection line or the quality control line;
the terminal detector sends the collected blood glucose concentration detected by the electrochemical blood glucose sensor and the brightness detected by the 8 light-receiving heads to the remote host;
the remote host is stored with 6 sex hormones and the corresponding ELISA working curve of blood sugar, the remote host calibrates the brightness of the blood sugar detected by the corresponding light receiving head according to the blood sugar concentration detected by the electrochemical blood sugar sensor, and then quantitatively calculates the index of the 6 sex hormones according to the calibrated blood sugar concentration, thereby eliminating the ELISA error caused by the environment and equipment error.
2. A remote endocrine disorder detecting device as claimed in claim 1, wherein:
the terminal detector and the terminal interaction module are integrally arranged, and the terminal interaction module is provided with a terminal display screen, an earphone, a microphone and a high-definition camera; the mobile equipment terminal is a mobile phone or a tablet computer.
3. A remote endocrine disorder detecting device as claimed in claim 1, wherein:
the terminal interaction module and the mobile equipment terminal are used for establishing video call connection with the remote analysis module when a doctor needs to communicate with a detector in a face-to-face mode.
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| CN202010007492.2A CN111166289B (en) | 2020-01-04 | 2020-01-04 | Remote endocrine disorder detection equipment |
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| CN202010007492.2A CN111166289B (en) | 2020-01-04 | 2020-01-04 | Remote endocrine disorder detection equipment |
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| CN111166289B true CN111166289B (en) | 2023-02-24 |
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| CN112133436B (en) * | 2020-10-13 | 2021-06-29 | 广州万孚健康科技有限公司 | Health warning method and system based on big data analysis and readable storage medium |
| CN114778629B (en) * | 2022-04-28 | 2023-10-20 | 孟栋栋 | Clinical blood drawing detection device for medical endocrinology department |
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| US8394246B2 (en) * | 2009-02-23 | 2013-03-12 | Roche Diagnostics Operations, Inc. | System and method for the electrochemical measurement of an analyte employing a remote sensor |
| CN102822834B (en) * | 2010-04-07 | 2020-09-25 | 诺华探索公司 | Computer-based system for predicting treatment outcome |
| CN101839908B (en) * | 2010-05-28 | 2014-08-20 | 李金波 | Quantitative detection device and detection method of biological fluid samples |
| CN102183570A (en) * | 2011-02-14 | 2011-09-14 | 北京软测科技有限公司 | Realization method for improving blood detection accuracy and detector |
| CN106169099A (en) * | 2012-08-01 | 2016-11-30 | 优菲米特有限责任公司 | User interface for analyte monitoring system |
| CN105266822B (en) * | 2014-05-27 | 2018-08-24 | 普林斯顿医疗科技（珠海）有限公司 | Lossless blood-sugar detecting instrument based on Ocular Vessels blood Raman scattering and detection method |
| CN104266996A (en) * | 2014-10-07 | 2015-01-07 | 复旦大学 | Multifunctional non-invasive and portable medical detection device and method based on near-infrared spectrum analysis |
| CN108354614A (en) * | 2017-01-26 | 2018-08-03 | 李韦辰 | Blood sugar detecting method, blood sugar test bearing calibration and blood sugar detection apparatus |
| CN109124648A (en) * | 2018-07-17 | 2019-01-04 | 桂林电子科技大学 | Insulin action factor calculation method based on energetic supersession conservation method noninvasive dynamics monitoring model |
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