CN111100032A - 一种含有乙氧基水杨醛缩1,4-丁二胺的稀土Schiff碱配合物的制备方法及其应用 - Google Patents
一种含有乙氧基水杨醛缩1,4-丁二胺的稀土Schiff碱配合物的制备方法及其应用 Download PDFInfo
- Publication number
- CN111100032A CN111100032A CN201911335205.4A CN201911335205A CN111100032A CN 111100032 A CN111100032 A CN 111100032A CN 201911335205 A CN201911335205 A CN 201911335205A CN 111100032 A CN111100032 A CN 111100032A
- Authority
- CN
- China
- Prior art keywords
- schiff base
- rare earth
- mixed solvent
- zinc
- base complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002262 Schiff base Substances 0.000 title claims abstract description 66
- -1 rare earth Schiff base Chemical class 0.000 title claims abstract description 44
- 229910052761 rare earth metal Inorganic materials 0.000 title claims abstract description 38
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 29
- 239000003814 drug Substances 0.000 claims abstract description 5
- 239000000126 substance Substances 0.000 claims abstract description 3
- 239000012046 mixed solvent Substances 0.000 claims description 38
- 150000004753 Schiff bases Chemical class 0.000 claims description 31
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 30
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims description 24
- 239000003446 ligand Substances 0.000 claims description 21
- KIDHWZJUCRJVML-UHFFFAOYSA-N putrescine Chemical compound NCCCCN KIDHWZJUCRJVML-UHFFFAOYSA-N 0.000 claims description 20
- 239000011701 zinc Substances 0.000 claims description 16
- 238000003756 stirring Methods 0.000 claims description 15
- 229910052751 metal Inorganic materials 0.000 claims description 14
- 239000002184 metal Substances 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 14
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 13
- 229910052725 zinc Inorganic materials 0.000 claims description 13
- 150000001875 compounds Chemical class 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- HXCVPMBZBRPZLX-UHFFFAOYSA-N 5-ethoxy-2-hydroxybenzaldehyde Chemical compound CCOC1=CC=C(O)C(C=O)=C1 HXCVPMBZBRPZLX-UHFFFAOYSA-N 0.000 claims description 10
- 150000003839 salts Chemical class 0.000 claims description 10
- 230000003385 bacteriostatic effect Effects 0.000 claims description 9
- GJKFIJKSBFYMQK-UHFFFAOYSA-N lanthanum(3+);trinitrate;hexahydrate Chemical compound O.O.O.O.O.O.[La+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O GJKFIJKSBFYMQK-UHFFFAOYSA-N 0.000 claims description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 238000005882 aldol condensation reaction Methods 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 6
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical compound [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 239000004246 zinc acetate Substances 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 4
- 229910052746 lanthanum Inorganic materials 0.000 claims description 4
- FZLIPJUXYLNCLC-UHFFFAOYSA-N lanthanum atom Chemical compound [La] FZLIPJUXYLNCLC-UHFFFAOYSA-N 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- VNDYJBBGRKZCSX-UHFFFAOYSA-L zinc bromide Chemical compound Br[Zn]Br VNDYJBBGRKZCSX-UHFFFAOYSA-L 0.000 claims description 4
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 claims description 4
- ONDPHDOFVYQSGI-UHFFFAOYSA-N zinc nitrate Chemical compound [Zn+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ONDPHDOFVYQSGI-UHFFFAOYSA-N 0.000 claims description 4
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 238000001704 evaporation Methods 0.000 claims description 2
- 238000003786 synthesis reaction Methods 0.000 claims description 2
- 229940102001 zinc bromide Drugs 0.000 claims description 2
- 239000011592 zinc chloride Substances 0.000 claims description 2
- 235000005074 zinc chloride Nutrition 0.000 claims description 2
- RXBXBWBHKPGHIB-UHFFFAOYSA-L zinc;diperchlorate Chemical compound [Zn+2].[O-]Cl(=O)(=O)=O.[O-]Cl(=O)(=O)=O RXBXBWBHKPGHIB-UHFFFAOYSA-L 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims 5
- 239000013078 crystal Substances 0.000 abstract description 9
- 238000012360 testing method Methods 0.000 abstract description 6
- 238000011160 research Methods 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract description 3
- 239000000243 solution Substances 0.000 description 34
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 8
- 241000894006 Bacteria Species 0.000 description 6
- 230000002401 inhibitory effect Effects 0.000 description 6
- 230000005764 inhibitory process Effects 0.000 description 6
- 241000588724 Escherichia coli Species 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000000725 suspension Substances 0.000 description 4
- 241000222122 Candida albicans Species 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 241000191967 Staphylococcus aureus Species 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 229940095731 candida albicans Drugs 0.000 description 3
- 229940125904 compound 1 Drugs 0.000 description 3
- 239000001963 growth medium Substances 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 244000063299 Bacillus subtilis Species 0.000 description 2
- 235000014469 Bacillus subtilis Nutrition 0.000 description 2
- 241000607142 Salmonella Species 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 238000002447 crystallographic data Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 239000011550 stock solution Substances 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 241000223602 Alternaria alternata Species 0.000 description 1
- 241000198596 Alternaria tomatophila Species 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 241000223218 Fusarium Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- 244000061176 Nicotiana tabacum Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 241000191963 Staphylococcus epidermidis Species 0.000 description 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 235000015278 beef Nutrition 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 229940125782 compound 2 Drugs 0.000 description 1
- 229940126214 compound 3 Drugs 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000000921 elemental analysis Methods 0.000 description 1
- 238000002329 infrared spectrum Methods 0.000 description 1
- CZMAIROVPAYCMU-UHFFFAOYSA-N lanthanum(3+) Chemical compound [La+3] CZMAIROVPAYCMU-UHFFFAOYSA-N 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- AICOOMRHRUFYCM-ZRRPKQBOSA-N oxazine, 1 Chemical compound C([C@@H]1[C@H](C(C[C@]2(C)[C@@H]([C@H](C)N(C)C)[C@H](O)C[C@]21C)=O)CC1=CC2)C[C@H]1[C@@]1(C)[C@H]2N=C(C(C)C)OC1 AICOOMRHRUFYCM-ZRRPKQBOSA-N 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 150000002910 rare earth metals Chemical class 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- HRSADIZPZPRZEI-UHFFFAOYSA-L zinc;diacetate;hydrate Chemical compound O.[Zn+2].CC([O-])=O.CC([O-])=O HRSADIZPZPRZEI-UHFFFAOYSA-L 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
- A01N55/02—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201911335205.4A CN111100032B (zh) | 2019-12-23 | 2019-12-23 | 一种含有乙氧基水杨醛缩1,4-丁二胺的稀土Schiff碱配合物的制备方法及其应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201911335205.4A CN111100032B (zh) | 2019-12-23 | 2019-12-23 | 一种含有乙氧基水杨醛缩1,4-丁二胺的稀土Schiff碱配合物的制备方法及其应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN111100032A true CN111100032A (zh) | 2020-05-05 |
CN111100032B CN111100032B (zh) | 2023-08-11 |
Family
ID=70423568
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201911335205.4A Active CN111100032B (zh) | 2019-12-23 | 2019-12-23 | 一种含有乙氧基水杨醛缩1,4-丁二胺的稀土Schiff碱配合物的制备方法及其应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN111100032B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113979890A (zh) * | 2021-10-27 | 2022-01-28 | 温州大学 | 一种席夫碱配体及其多核稀土配合物的制备方法和应用 |
CN115340478A (zh) * | 2022-06-30 | 2022-11-15 | 温州医科大学 | 一种席夫碱配体及其多核稀土配合物的制备方法和应用 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1466419A (zh) * | 2000-09-29 | 2004-01-07 | ���Ͽع�����˾ | 具有抗菌活性的稳定组合物 |
CN108350008A (zh) * | 2016-03-17 | 2018-07-31 | 深圳市塔吉瑞生物医药有限公司 | 一种新型的无环核苷类似物及其药物组合物 |
CN108570076A (zh) * | 2018-05-04 | 2018-09-25 | 广东药科大学 | 一种含炔基的钌配合物及其合成方法与应用 |
US20190029998A1 (en) * | 2016-01-29 | 2019-01-31 | Wichita State University | Compounds for inhibiting bacterial growth via phosphatidylglycerol binding |
CN110066241A (zh) * | 2019-05-23 | 2019-07-30 | 陕西理工大学 | 一种锌的Schiff碱配合物及其制备方法和应用 |
-
2019
- 2019-12-23 CN CN201911335205.4A patent/CN111100032B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1466419A (zh) * | 2000-09-29 | 2004-01-07 | ���Ͽع�����˾ | 具有抗菌活性的稳定组合物 |
US20190029998A1 (en) * | 2016-01-29 | 2019-01-31 | Wichita State University | Compounds for inhibiting bacterial growth via phosphatidylglycerol binding |
CN108350008A (zh) * | 2016-03-17 | 2018-07-31 | 深圳市塔吉瑞生物医药有限公司 | 一种新型的无环核苷类似物及其药物组合物 |
CN108570076A (zh) * | 2018-05-04 | 2018-09-25 | 广东药科大学 | 一种含炔基的钌配合物及其合成方法与应用 |
CN110066241A (zh) * | 2019-05-23 | 2019-07-30 | 陕西理工大学 | 一种锌的Schiff碱配合物及其制备方法和应用 |
Non-Patent Citations (2)
Title |
---|
NIDHI DWIVEDI等: "Molecular Packing Dependent Solid State Fluorescence Response of Supramolecular Metal−Organic Frameworks: Phenoxo-Bridged Trinuclear Zn(II) Centered Schiff Base Complexes with Halides andPseudohalides", 《CRYSTAL GROWTH & DESIGN》 * |
NIDHI DWIVEDI等: "NIR luminescent heterodinuclear [ZnIILnIII] complexes: Synthesis, crystalstructures and photophysical properties", 《JOURNAL OF LUMINESCENCE》 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113979890A (zh) * | 2021-10-27 | 2022-01-28 | 温州大学 | 一种席夫碱配体及其多核稀土配合物的制备方法和应用 |
CN113979890B (zh) * | 2021-10-27 | 2023-09-26 | 温州大学 | 一种席夫碱配体及其多核稀土配合物的制备方法和应用 |
CN115340478A (zh) * | 2022-06-30 | 2022-11-15 | 温州医科大学 | 一种席夫碱配体及其多核稀土配合物的制备方法和应用 |
CN115340478B (zh) * | 2022-06-30 | 2023-10-27 | 温州医科大学 | 一种席夫碱配体及其多核稀土配合物的制备方法和应用 |
Also Published As
Publication number | Publication date |
---|---|
CN111100032B (zh) | 2023-08-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN111100032A (zh) | 一种含有乙氧基水杨醛缩1,4-丁二胺的稀土Schiff碱配合物的制备方法及其应用 | |
Chrysouli et al. | Ciprofloxacin conjugated to diphenyltin (IV): a novel formulation with enhanced antimicrobial activity | |
Kalaiarasi et al. | Cyclometallated ruthenium (II) complexes with 3-acetyl-2 [H]-chromene-2-one derived CNS chelating ligand systems: Synthesis, X-ray characterization and biological evaluation | |
CN108503726B (zh) | 一种酞菁-壳寡糖偶联物及其制备方法与应用 | |
CN102286010A (zh) | N-(2-乙酸)水杨酰腙稀土配合物及其制备方法和用途 | |
CN103755730A (zh) | 马波沙星-钙螯合物及其合成方法和应用 | |
CN102875528A (zh) | 含有多酸阴离子的喹诺酮金属配合物及其制备方法 | |
CN111087429B (zh) | 一种具有光活化抗菌的钌配合物及其制备方法和应用 | |
CN103524417B (zh) | 一组3-甲基-4-甲酰吡唑化合物 | |
CN110372588B (zh) | 一种4-胺基喹啉化合物及其制备方法和应用 | |
CN110054606B (zh) | 一种二氢杨梅素-盐酸黄连素药物共晶及制备方法 | |
CN111349038B (zh) | 一类吲哚酰腙化合物及其制备方法和在防治植物病害中的应用 | |
CN111937886A (zh) | 一种8-羟基喹啉配合物的制备及其在防治植物病害中的用途 | |
CN102382206B (zh) | 壳寡糖季铵盐及其制备方法 | |
CN109305987B (zh) | 环丙沙星金属配合物及其制备方法和应用 | |
CN109305988A (zh) | 环丙沙星金属配合物及其制备方法和应用 | |
CN111499523B (zh) | 一种辛菌胺络合物及其制备方法和应用 | |
CN108017664A (zh) | 一种对氨基苯磺酸金属配合物抗菌剂及其制备方法和应用 | |
Patil et al. | Synthesis, Characterization and Antibacterial Activity of Mixed Ligand Dioxouranium Complexes of 8-Hydroxyquinoline and Some Amino Acids | |
CN112790195B (zh) | 防霉型粘合剂及其制备方法和应用 | |
C. Tella et al. | Copper (II) Complexes of 4, 4‐Diaminodiphenylsulphone: Synthesis, Characterization and Biological Studies | |
CN104961752A (zh) | 一种双核铜(ii)–唑来膦酸配合物及应用 | |
CN111349080B (zh) | 一种吲哚酰腙化合物及其制备方法和在防治植物病害中的应用 | |
CN103554026B (zh) | 一组3-三氟甲基-4-甲酰吡唑化合物 | |
Sridevi et al. | Theoretical and experimental studies of novel histidine derived Schiff base metal complexes, active towards biomedical and MCF 7 cell lines |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20240617 Address after: 518000 1002, Building A, Zhiyun Industrial Park, No. 13, Huaxing Road, Henglang Community, Longhua District, Shenzhen, Guangdong Province Patentee after: Shenzhen Wanzhida Technology Co.,Ltd. Country or region after: China Address before: 723001 School of chemistry and Environmental Sciences, Shaanxi University of technology, Hanzhong City, Shaanxi Province Patentee before: Shaanxi University of Technology Country or region before: China |
|
TR01 | Transfer of patent right |