CN111093682A - 丁酸杆菌(Butyribacter intestini)在预防和/或治疗炎症相关疾病的应用 - Google Patents

丁酸杆菌(Butyribacter intestini)在预防和/或治疗炎症相关疾病的应用 Download PDF

Info

Publication number
CN111093682A
CN111093682A CN201780094565.2A CN201780094565A CN111093682A CN 111093682 A CN111093682 A CN 111093682A CN 201780094565 A CN201780094565 A CN 201780094565A CN 111093682 A CN111093682 A CN 111093682A
Authority
CN
China
Prior art keywords
composition
butyric acid
intestini
group
inflammation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201780094565.2A
Other languages
English (en)
Other versions
CN111093682B (zh
Inventor
邹远强
肖亮
李晓平
余靖宏
刘传
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuhan Huada Institute Of Life Sciences
Original Assignee
BGI Shenzhen Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BGI Shenzhen Co Ltd filed Critical BGI Shenzhen Co Ltd
Publication of CN111093682A publication Critical patent/CN111093682A/zh
Application granted granted Critical
Publication of CN111093682B publication Critical patent/CN111093682B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

本发明提供了一种丁酸杆菌(Butyribacter intestini)在预防和/或治疗炎症相关疾病的应用，具体地，本发明首次发现丁酸杆菌(Butyribacter intestini)具有预防和/或治疗炎症相关疾病(如炎症性肠病(如溃疡性肠炎、胃炎、普通肠炎)、类风湿性关节炎)的作用。

Description

PCT国内申请，说明书已公开。

Claims (15)

  1. PCT国内申请，权利要求书已公开。
CN201780094565.2A 2017-12-08 2017-12-08 丁酸杆菌(Butyribacter intestini)在预防和/或治疗炎症相关疾病的应用 Active CN111093682B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2017/115278 WO2019109348A1 (zh) 2017-12-08 2017-12-08 丁酸杆菌(Butyribacter intestini)在预防和/或治疗炎症相关疾病的应用

Publications (2)

Publication Number Publication Date
CN111093682A true CN111093682A (zh) 2020-05-01
CN111093682B CN111093682B (zh) 2024-01-16

Family

ID=66750719

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780094565.2A Active CN111093682B (zh) 2017-12-08 2017-12-08 丁酸杆菌(Butyribacter intestini)在预防和/或治疗炎症相关疾病的应用

Country Status (6)

Country Link
US (1) US11338000B2 (zh)
EP (1) EP3721889B1 (zh)
JP (1) JP7189954B2 (zh)
CN (1) CN111093682B (zh)
DK (1) DK3721889T3 (zh)
WO (1) WO2019109348A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113304175A (zh) * 2021-07-08 2021-08-27 温州医科大学 丁酸杆菌在制备预防和/或治疗川崎病药物中的应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110964650B (zh) * 2018-09-27 2022-10-11 上海上药信谊药厂有限公司 一种用于预防和治疗代谢疾病的菌株及其应用

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1446103A (zh) * 2000-07-03 2003-10-01 普罗本多有限公司 采用益生菌治疗内毒素血症及相关疾病
CN105106244A (zh) * 2015-08-06 2015-12-02 温州医科大学附属第二医院 一种防治糖尿病脑病的益生菌制剂及其制备方法
EP2995314A1 (en) * 2014-09-12 2016-03-16 Swecure AB Use of collinsella for treatment of inflammatory bowel disease
CN105687252A (zh) * 2016-03-22 2016-06-22 温州医科大学附属第二医院 丁酸杆菌在制备治疗和/或预防急性肝损伤药物中的应用
CN106479906A (zh) * 2015-08-27 2017-03-08 深圳华大基因研究院 肠道细菌丁酸杆菌（Butyribacter intestini)及其应用
CN106974262A (zh) * 2016-01-15 2017-07-25 深圳华大基因研究院 肠道益生杆菌在治疗和预防肥胖及其相关疾病中的应用
CN106994134A (zh) * 2016-01-25 2017-08-01 深圳华大基因研究院 肠道益生菌在预防和/或治疗糖尿病及其相关疾病中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8092793B2 (en) * 2004-12-15 2012-01-10 Qingdao East Sea Pharmaceuticals, Ltd. Treating inflammatory bowel disease with live bacteria
US9125935B1 (en) * 2011-05-31 2015-09-08 Nutech Ventures Probiotics and methods of obtaining same
US11376289B2 (en) * 2018-05-31 2022-07-05 Bgi Shenzhen Composition and uses thereof
WO2019227417A1 (zh) 2018-05-31 2019-12-05 深圳华大生命科学研究院 一种组合物及其应用

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1446103A (zh) * 2000-07-03 2003-10-01 普罗本多有限公司 采用益生菌治疗内毒素血症及相关疾病
EP2995314A1 (en) * 2014-09-12 2016-03-16 Swecure AB Use of collinsella for treatment of inflammatory bowel disease
CN105106244A (zh) * 2015-08-06 2015-12-02 温州医科大学附属第二医院 一种防治糖尿病脑病的益生菌制剂及其制备方法
CN106479906A (zh) * 2015-08-27 2017-03-08 深圳华大基因研究院 肠道细菌丁酸杆菌（Butyribacter intestini)及其应用
CN106974262A (zh) * 2016-01-15 2017-07-25 深圳华大基因研究院 肠道益生杆菌在治疗和预防肥胖及其相关疾病中的应用
CN106994134A (zh) * 2016-01-25 2017-08-01 深圳华大基因研究院 肠道益生菌在预防和/或治疗糖尿病及其相关疾病中的应用
CN105687252A (zh) * 2016-03-22 2016-06-22 温州医科大学附属第二医院 丁酸杆菌在制备治疗和/或预防急性肝损伤药物中的应用

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
唐玉芬等: "炎症性肠病与微生态制剂", 《胃肠病学和肝病学杂志》 *
李佳等: "益生菌在溃疡性结肠炎中的应用", 《辽宁中医药大学学报》 *
熊祖明等: "酪酸梭菌的研究与应用进展", 《中国微生态学杂志》 *
陈筱筱等: "酪酸梭状芽孢杆菌生理功能的研究进展", 《中外医疗》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113304175A (zh) * 2021-07-08 2021-08-27 温州医科大学 丁酸杆菌在制备预防和/或治疗川崎病药物中的应用

Also Published As

Publication number Publication date
DK3721889T3 (da) 2023-07-03
EP3721889A1 (en) 2020-10-14
JP2021505609A (ja) 2021-02-18
US20210085730A1 (en) 2021-03-25
EP3721889B1 (en) 2023-05-17
US11338000B2 (en) 2022-05-24
JP7189954B2 (ja) 2022-12-14
CN111093682B (zh) 2024-01-16
WO2019109348A1 (zh) 2019-06-13
EP3721889A4 (en) 2021-05-19

Similar Documents

Publication Publication Date Title
CN106994134B (zh) 肠道益生菌在预防和/或治疗糖尿病及其相关疾病中的应用
CN111280252B (zh) 长双歧杆菌长亚种、含其的组合物及用途
CN109419816B (zh) 解纤维素拟杆菌在预防和/或治疗心脏疾病方面的应用
JP6990303B2 (ja) Ｍｅｇａｍｏｎａｓ ｆｕｎｉｆｏｒｍｉｓ及びその適用
CN106974262B (zh) 肠道益生杆菌在治疗和预防肥胖及其相关疾病中的应用
CN106479906B (zh) 肠道细菌丁酸杆菌(Butyribacter intestini)及其应用
CN112888448B (zh) 单形巨单胞菌在预防和/或治疗代谢性疾病中的用途
CN111281894B (zh) 加氏乳杆菌在预防和/或治疗代谢性疾病中的用途和组合物
CN111093682B (zh) 丁酸杆菌(Butyribacter intestini)在预防和/或治疗炎症相关疾病的应用
US20090311227A1 (en) Composition
CN117645955A (zh) 具有促进肠上皮细胞恢复作用的直肠真杆菌及其应用
CN107028985A (zh) 厚壁菌类益生菌在预防和/或治疗糖尿病及其相关疾病中的应用
CN110869035B (zh) 沙氏别样杆菌在制备预防和/或治疗脂质代谢性相关疾病组合物中的应用
CN110062806B (zh) 粪厌氧棒杆菌(Anaerostipes caccae)及其应用
CN111448306B (zh) 粪厌氧棒形菌(Anaerofustis stercorihominis)及其应用
WO2018107364A1 (zh) 深圳柯林斯菌(Collinsella shenzhenensis)及其应用
CN112236154A (zh) 一种组合物及其应用
CN106974939B (zh) 厚壁菌类益生菌在治疗和预防肥胖及其相关疾病中的应用
CN106974940B (zh) 厚壁菌类益生菌在治疗和预防肥胖及其相关疾病中的应用
CN107080756B (zh) 链球菌属益生菌在预防和/或治疗糖尿病及其相关疾病中的应用
CN112867500B (zh) 人粪厌氧棒形菌在预防和/或治疗代谢性疾病中的用途
CN116942706A (zh) Akkermansia muciniphila在制备预防、治疗和/或辅助治疗肠炎的产品中的应用

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40017896

Country of ref document: HK

GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20240329

Address after: Building 1-2, Phase 3.1, Wuhan Optics Valley International Biopharmaceutical Enterprise Accelerator, No. 388 Gaoxin Second Road, Donghu New Technology Development Zone, Wuhan City, Hubei Province, 430206

Patentee after: Wuhan Huada Institute of Life Sciences

Country or region after: China

Address before: 518083 Yantian District, Yantian District, Shenzhen, Guangdong.

Patentee before: BGI SHENZHEN

Country or region before: China

TR01 Transfer of patent right