CN110897950A

CN110897950A - Facial mask with anti-inflammatory, moisturizing and whitening effects and preparation method thereof

Info

Publication number: CN110897950A
Application number: CN201911055997.XA
Authority: CN
Inventors: 闫长宝
Original assignee: Beijing Matian Biotechnology Co Ltd
Current assignee: Beijing Matian Biotechnology Co Ltd
Priority date: 2019-10-31
Filing date: 2019-10-31
Publication date: 2020-03-24

Abstract

The invention belongs to the field of cosmetics, and particularly relates to a facial mask with anti-inflammatory, moisturizing and whitening effects, which comprises the following raw materials in percentage by mass: 1 to 3 percent of cannabidiol, 0.3 to 1.0 percent of glycerol glucoside, 0.05 to 0.2 percent of dipotassium glycyrrhizinate, 1 to 5 percent of 1, 3-propylene glycol, 0.5 to 2.0 percent of glycerol, 0.05 to 0.1 percent of sodium hyaluronate, 0.01 to 0.05 percent of sodium polyglutamate, 0.5 to 1.0 percent of saccharide isomer, 0.5 to 1.0 percent of caprylyl hydroximic acid, 0.1 to 0.2 percent of thickening agent, 0.01 to 0.05 percent of chelating agent, 0.01 to 0.1 percent of preservative, 0.1 to 0.3 percent of pH regulator, 0.001 to 0.005 percent of aromatic, 0.01 to 0.05 percent of solubilizer and the balance of water. The preparation method of the facial mask comprises the following steps: and adding the carbomer serving as the raw material in the phase A into a water phase pot containing water and EDTA disodium under the condition of rapid stirring, heating to 85 ℃ under the stirring of 30Hz, stirring until the carbomer is dissolved uniformly, pumping into a main pot, and the like. According to the invention, as the cannabidiol is added into the components and the rich and various functional components are mutually blended, the product has remarkable effects of resisting inflammation, moisturizing and whitening the skin.

Description

Facial mask with anti-inflammatory, moisturizing and whitening effects and preparation method thereof

Technical Field

The invention relates to the field of cosmetics, in particular to a mask with anti-inflammatory, moisturizing and whitening effects.

Background

With the development of society, people pursue beauty more and more. However, due to the influence of computer radiation, outdoor ultraviolet irradiation, dietary factors, living pressure and the like, the face of people is damaged, and the face of some people has symptoms such as allergy, acne, face itching due to wind blowing, dryness and peeling, so that people are worried, especially young people secrete vigorous secretion, and particularly the whelks are the most common. Although a lot of beauty products are used for treating whelk, the effect is not obvious, the skin burden is increased after long-term use, and red swelling, suppuration, pain and the like of the skin are easily caused. Meanwhile, the products often contain hormone substances, although symptoms can be relieved in a short period, pigment spots can be left after long-term use, irreversible influence is generated on the skin, and psychological and physiological damage is caused to patients.

Disclosure of Invention

The technical problem to be solved by the invention is to provide a facial mask with anti-inflammatory, moisturizing and whitening effects, so as to improve the antibacterial and anti-inflammatory effects.

In order to solve the technical problems, the technical scheme of the invention is as follows:

the facial mask with the anti-inflammatory, moisturizing and whitening effects comprises the following raw materials in percentage by mass: 1-3% of wrapped hemp leaf extract, 0.3-1.0% of glycerol glucoside, 0.05-0.2% of dipotassium glycyrrhizinate, 1, 3-propylene glycol 1-5%, 0.5-2.0% of glycerol, 0.05-0.1% of sodium hyaluronate, 0.01-0.05% of sodium polyglutamate, 0.5-1.0% of saccharide isomer, 0.5-1.0% of caprylyl hydroximic acid, 0.1-0.2% of thickening agent, 0.01-0.05% of chelating agent, 0.01-0.1% of preservative, 0.1-0.3% of pH regulator, 0.001-0.005% of aromatic, 0.01-0.05% of solubilizer and the balance of water.

In the facial mask with anti-inflammatory, moisturizing and whitening effects provided by the invention, the facial mask preferably comprises the following raw materials in percentage by mass: 1.5 to 2.5 percent of wrapped hemp leaf extract, 0.5 to 0.8 percent of glycerol glucoside, 0.05 to 0.1 percent of dipotassium glycyrrhizinate, 3 to 5 percent of 1, 3-propylene glycol, 0.5 to 1.5 percent of glycerol, 0.05 to 0.08 percent of sodium hyaluronate, 0.01 to 0.03 percent of sodium polyglutamate, 0.5 to 0.8 percent of saccharide isomer, 0.5 to 0.8 percent of caprylyl hydroximic acid, 0.15 to 0.2 percent of thickening agent, 0.01 to 0.03 percent of chelating agent, 0.05 to 0.1 percent of preservative, 0.1 to 0.2 percent of PH regulator, 0.003 to 0.005 percent of aromatic, 0.01 to 0.03 percent of solubilizer and the balance of water.

In the facial mask with anti-inflammatory, moisturizing and whitening effects provided by the invention, the facial mask preferably comprises the following raw materials in percentage by mass: 2% of wrapped hemp leaf extract, 0.5% of glycerol glucoside, 0.1% of dipotassium glycyrrhizinate, 4% of 1, 3-propylene glycol, 1% of glycerol, 0.06% of sodium hyaluronate, 0.02% of sodium polyglutamate, 0.5% of carbohydrate isomer, 0.6% of caprylyl hydroximic acid, 0.17% of thickening agent, 0.02% of chelating agent, 0.05% of preservative, 0.14% of pH regulator, 0.003% of aromatic, 0.01% of solubilizer and the balance of water.

In the present invention, the water may be deionized water, purified water or distilled water; the thickening agent can be hydrolyzed sclerotium rolfsii gum or carbomer or a mixture of the hydrolyzed sclerotium rolfsii gum and the carbomer; the chelating agent can be disodium EDTA, etc.; the antiseptic can be chlorphenesin, etc.; the pH regulator may be arginine, etc.; the aromatic agent can be Prunus humilis Bunge flower; the solubilizer can be PEG-40 hydrogenated castor oil, etc.

Preferably, the sodium hyaluronate is a complex of sodium hyaluronate of ordinary molecular weight and oligomeric sodium hyaluronate.

On the other hand, the technical problem to be solved by the invention is a preparation method of the facial mask with anti-inflammatory, moisturizing and whitening effects, which divides the raw materials into the following four phases,

phase A comprises water, disodium EDTA, 1, 3-propylene glycol, glycerol, hydrolyzed sclerotium rolfsii gum, sodium hyaluronate, sodium polyglutamate, carbomer, chlorphenesin and dipotassium glycyrrhizinate;

phase B comprises arginine;

the phase C comprises glycerol glucoside, saccharide isomer, caprylyl hydroxamic acid, and wrapped folium Cannabis extract;

phase D comprises flos Pruni Salicinae and PEG-40 hydrogenated castor oil.

The preparation method comprises the following steps:

step one, adding carbomer serving as a raw material in the phase A into an aqueous phase pot containing water and EDTA disodium under rapid stirring, stirring at 30Hz, heating to 85 ℃, stirring until the carbomer is dissolved uniformly, and pumping into a main pot;

step two, adding the raw materials of 1, 3-propylene glycol, hydrolyzed sclerotium rolfsii gum, sodium hyaluronate, sodium polyglutamate and sodium hyaluronate pre-dispersed in the phase A into a preparation pot, stirring at 30Hz until the raw materials are completely dissolved, then sequentially adding the rest raw materials in the phase A into the preparation pot, stirring until the raw materials are uniform, and cooling;

step three, cooling to 70 ℃, adding the diluent prepared from the phase B into a preparation pot with the concentration of 10% into the preparation pot, stirring the mixture evenly at 30Hz, and continuously cooling;

step four, cooling to 45 ℃, sequentially adding the C-phase raw materials into a preparation pot, stirring, and continuing stirring at 30Hz for cooling;

and step five, cooling to 40 ℃, adding the phase D after pre-dissolution into a preparation pot, stirring uniformly at 25Hz, taking materials, detecting, filtering with 200-mesh filter cloth after passing, and discharging.

Several components of the present invention are described below:

the cannabis leaf extract is wrapped, the main component of Cannabidiol (CBD) is the main chemical component in the medicinal plant cannabis, the cannabis is a non-addictive component in the cannabis, the anti-inflammatory effect is high, the skin inflammatory symptoms such as acne, eczema and psoriasis can be improved, and the effects of moisture retention, oxidation resistance and the like are achieved.

Dipotassium glycyrrhizinate (Dipotassium Glycyrrhetate) is white powder, sweet in taste, soluble in water, glycerol and propylene glycol, and slightly soluble in absolute ethyl alcohol and diethyl ether. The dipotassium glycyrrhizinate has the effects of resisting inflammation, resisting allergy, preserving moisture and the like. In the pharmaceutical industry, can be used for eye drops and ointment for stomatitis; in the cosmetic industry, the product can be used as skin care product and face cream; in the daily chemical industry, the toothpaste can be used; in the food industry, the potassium replenishing agent can be used as a potassium replenishing agent, a sweet agent, an antistaling agent and a flavoring agent for sports drinks.

The glucoside, APG for short, is synthesized by renewable resources, namely natural fatty alcohol and glucose, is a novel nonionic surfactant with comprehensive performance, has the characteristics of common nonionic and anionic surfactants, has high surface activity, good ecological safety and intermiscibility, and simultaneously has the function of humidifying, and completely meets the performance requirements of active components for cosmetics. APG has been used as an active ingredient to make cosmetics at home and abroad, and such novel cosmetics exhibit good skin moisturizing and skin care properties.

Compared with the prior art, the invention has the following technical effects:

the active component of the facial mask with the anti-inflammatory, moisturizing and whitening effects is the extract of the wrapped hemp leaves, the raw material of the wrapped hemp leaf extract meets the requirement of 'announcement of the national food and drug administration for releasing the name of used cosmetic raw materials (2015 edition) (No. 105 in 2015)', and simultaneously meets the control requirement of the public safety and toxicity control department on industrial hemp products.

In the invention, because the hemp leaf-wrapped extract is added into the components and the rich functional components are mutually blended, the product has the remarkable effects of resisting inflammation, preserving moisture and whitening skin, has the effects of inhibiting bacteria, resisting inflammation and the like, has no stimulation, allergy or toxic or side effect to skin, and is suitable for long-term use.

Detailed Description

The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.

Examples 1-3 and comparative examples 1-3 each provide a composition having the following formulation, in mass percent, as set forth in table 1 below.

	Example 1	Example 2	Example 3	Comparative example 1	Comparative example 2	Comparative example 3
							Wrapped hemp leaf extract	1.0	2.0	3.0	0	2.0	2.0
Glycerol glucoside	0.3	0.2	1.0	0.2	0	0.2
							Glycyrrhizic acid dipotassium salt	0.05	0.1	0.2	0.1	0.1	0
1, 3-propanediol	1.0	4.0	5.0	4.0	4.0	4.0
							Glycerol	0.5	1.0	2.0	1.0	1.0	1.0
Hyaluronic acid sodium salt	0.01	0.03	0.05	0.03	0.03	0.03
							Polyglutamic acid sodium salt	0.01	0.02	0.05	0.02	0.02	0.02
Saccharide isomerate	0.5	0.6	1.0	0.6	0.6	0.6
							Octanoyl hydroximic acid	0.5	0.6	1.0	0.6	0.6	0.6
Thickening agent	0.1	0.12	0.2	0.12	0.12	0.12
							Chelating agents	0.01	0.05	0.1	0.05	0.05	0.05
Preservative	0.01	0.05	0.1	0.05	0.05	0.05
							PH regulator	0.1	0.14	0.3	0.14	0.14	0.14
Aromatic agent	0.001	0.003	0.005	0.003	0.003	0.003
							Solubilizer	0.01	0.01	0.05	0.01	0.01	0.01
Deionized water	Balance of	Balance of	Balance of	Balance of	Balance of	Balance of

The compositions of examples 1-3 were prepared by the following procedure:

the raw material is divided into the following four phases,

phase B comprises arginine;

phase D comprises flos Pruni Salicinae and PEG-40 hydrogenated castor oil.

The preparation method comprises the following steps:

Comparative example 1

The difference from the embodiment 2 is that the hemp leaf extract is not contained, and the addition of other components and the preparation process are not changed.

Comparative example 2

The difference from the example 2 is only that glycerol glucoside is not contained, the other components are added, and the preparation process is not changed.

Comparative example 3

The differences from the embodiment 2 are only that dipotassium glycyrrhizinate is not contained, the addition of other component substances and the preparation process are not changed.

Efficacy testing

Test example 1

Testing the healing effect of skin allergy:

60 women between 20 and 40 years old and patients with face allergy are selected, the products prepared in the embodiments 1-3 and the comparative examples 1-3 are tried, 10 persons are randomly selected from the products in each group, the test is carried out for 45 days, and the wiping is carried out after the face is cleaned in the morning and at the evening every day, and the effects are shown in the following table 2:

the criteria for "significant improvement" in table 2 are: the allergy is obviously reduced or disappeared.

The criteria for "mitigation" in table 2 are: reduce allergy to a certain extent, reduce swelling and reduce inflammation.

As can be seen from Table 2, the products of examples 1-3 were significantly improved at a high rate after 45 days of continuous use, significantly higher than the products of comparative examples 1-3, and had no side effects, and no irritation to human skin. The product prepared in example 2 has better treatment effects on symptoms such as skin allergy and pruritus.

Test example 2

Healing efficacy test of skin acne:

selecting 60 facial acne patients between 20-40 years old, trying the products prepared in the embodiments 1-3 and the comparative examples 1-3, randomly selecting 10 people from each group of products, testing for 45 days, cleaning the face every morning and evening, and then wiping, wherein the effects are shown in table 2:

	obviously improve	Mitigation	No effect	Side effects
					Example 1	7	3	0	0
Example 2	9	1	0	0
					Example 3	8	2	0	0
Comparative example 1	0	0	10	0
					Comparative example 2	0	1	9	0
Comparative example 3	0	1	9	0

The criteria for "significant improvement" in table 2 are: acne is significantly reduced or eliminated.

The criteria for "mitigation" in table 2 are: the acne is relieved to a certain extent, and swelling and inflammation are reduced.

As can be seen from Table 2, the products of examples 1-3 were significantly improved at a high rate after 45 days of continuous use, significantly higher than the products of comparative examples 1-3, and had no side effects, and no irritation to human skin. Among them, the product prepared in example 2 has better treatment of acne symptoms.

Test example 3

Whitening efficacy test (T/ZHCA 001-2018)

Reagents and materials: laboratory water, which adopts tertiary water in GB/T6682; masks in examples 1 to 3 and comparative examples 1 to 3; a non-dusting absorbent dry tissue.

Testing instrument

A tristimulus value colorimeter; analytical balance, precision 0.0001 g.

And (3) testing conditions are as follows:

testing the environmental temperature of 20-22 ℃ and the relative humidity of 40-60%, and carrying out real-time dynamic monitoring;

the testing conditions of testers, places, instruments and the like in the testing process are kept consistent.

Test method

The number of the testees is 30, the test part is the forearm area side, and before each test, the testees clean the tested part uniformly and suck the tested part by using a non-scrap water-absorbing dry paper towel.

The product is required to be evenly smeared; the left and right arms were randomized to test areas and the subjects were applied once a day, morning and evening, for a 5 week period. During the test period, the test area was not filled with any other cosmetic.

The test results are shown in Table 2.

As can be seen from table 2, the skin ITA ° values of the samples tested at the test sites tended to increase compared to the initial values over the time period from week 0 to week 5 of the experimental period. Among them, the difference of the ITA ° values of the test groups of examples 1 to 3 is significantly different, and the difference of the ITA ° values of the test groups of comparative examples 1 to 3 is not significant, so that the whitening effect of the test groups of examples 1 to 3 is significantly higher than that of the test groups of comparative examples 1 to 3. Wherein example 2 is more superior to examples 1 and 2 in effect.

The embodiments of the present invention have been described in detail, but the embodiments are only examples, and the present invention is not limited to the above-described embodiments. Any equivalent modifications and substitutions to those skilled in the art are also within the scope of the present invention. Therefore, equivalent changes and modifications made without departing from the spirit and scope of the present invention should be covered by the present invention.

Claims

1. The mask with the anti-inflammatory, moisturizing and whitening effects is characterized by comprising the following raw materials in percentage by mass: 1 to 3 percent of cannabidiol, 0.3 to 1.0 percent of glycerol glucoside, 0.05 to 0.2 percent of dipotassium glycyrrhizinate, 1 to 5 percent of 1, 3-propylene glycol, 0.5 to 2.0 percent of glycerol, 0.05 to 0.1 percent of sodium hyaluronate, 0.01 to 0.05 percent of sodium polyglutamate, 0.5 to 1.0 percent of saccharide isomer, 0.5 to 1.0 percent of caprylyl hydroximic acid, 0.1 to 0.2 percent of thickening agent, 0.01 to 0.05 percent of chelating agent, 0.01 to 0.1 percent of preservative, 0.1 to 0.3 percent of pH regulator, 0.001 to 0.005 percent of aromatic, 0.01 to 0.05 percent of solubilizer and the balance of water.

2. The anti-inflammatory, moisturizing and whitening mask as claimed in claim 1, which is characterized by comprising the following raw materials in percentage by mass: 1.5 to 2.5 percent of cannabidiol, 0.5 to 0.8 percent of glycerol glucoside, 0.05 to 0.1 percent of dipotassium glycyrrhizinate, 3 to 5 percent of 1, 3-propylene glycol, 0.5 to 1.5 percent of glycerol, 0.05 to 0.08 percent of sodium hyaluronate, 0.01 to 0.03 percent of sodium polyglutamate, 0.5 to 0.8 percent of saccharide isomer, 0.5 to 0.8 percent of caprylyl hydroximic acid, 0.15 to 0.2 percent of thickening agent, 0.01 to 0.03 percent of chelating agent, 0.05 to 0.1 percent of preservative, 0.1 to 0.2 percent of PH regulator, 0.003 to 0.005 percent of aromatic, 0.01 to 0.03 percent of solubilizer and the balance of water.

3. The anti-inflammatory, moisturizing and whitening mask as claimed in claim 2, which is characterized by comprising the following raw materials in percentage by mass: cannabidiol 2%, glycerol glucoside 0.5%, dipotassium glycyrrhizinate 0.1%, 1, 3-propylene glycol 4%, glycerol 1%, sodium hyaluronate 0.06%, sodium polyglutamate 0.02%, saccharide isomer 0.5%, caprylyl hydroximic acid 0.6%, thickening agent 0.17%, chelating agent 0.02%, preservative 0.05%, pH regulator 0.14%, aromatic 0.003%, solubilizing agent 0.01%, and the balance of water.

4. An anti-inflammatory moisturizing and whitening mask as in any of claims 1 to 3, characterized in that the sodium hyaluronate is a complex of sodium hyaluronate of ordinary molecular weight and oligomeric sodium hyaluronate.

5. An anti-inflammatory moisturizing and whitening mask as claimed in any of claims 1 to 3, characterized in that the water is deionized water, purified water or distilled water;

the thickening agent is selected from hydrolyzed sclerotium rolfsii gum or/and carbomer;

the chelating agent is selected from disodium EDTA;

the preservative is selected from chlorphenesin;

the pH regulator is selected from arginine;

the aromatic is selected from Prunus humilis Bunge flower;

the solubilizer is selected from PEG-40 hydrogenated castor oil.

6. A method for preparing a mask having anti-inflammatory, moisturizing and whitening effects according to any one of claims 1 to 3,

firstly, the raw material is divided into the following four phases,

phase B comprises arginine;

the phase C comprises glycerol glucoside, saccharide isomer, octanoyl hydroximic acid, and cannabidiol;

phase D comprises flos Pruni Salicinae and PEG-40 hydrogenated castor oil.

The preparation method comprises the following steps:

step one, adding carbomer serving as a raw material in the phase A into a water phase pot containing water and EDTA disodium under the condition of rapid stirring, heating to 85 ℃ under the stirring of 30Hz, stirring until the carbomer is dissolved uniformly, and pumping into a main pot;

step two, adding the raw materials of 1, 3-propylene glycol, hydrolyzed sclerotium rolfsii gum, sodium hyaluronate, sodium polyglutamate and sodium hyaluronate pre-dispersed in the phase A into a preparation pot, stirring at 30Hz until the raw materials are completely dissolved, then sequentially adding the rest raw materials in the phase A into the preparation pot, stirring uniformly, and cooling;

and step five, cooling to 40 ℃, adding the phase D after pre-dissolution into a preparation pot, stirring uniformly at 25Hz, taking materials, detecting, filtering with 200-mesh filter cloth after qualification, and discharging.