CN1107514C - Laxative and its preparation - Google Patents
Laxative and its preparation Download PDFInfo
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- CN1107514C CN1107514C CN00107319A CN00107319A CN1107514C CN 1107514 C CN1107514 C CN 1107514C CN 00107319 A CN00107319 A CN 00107319A CN 00107319 A CN00107319 A CN 00107319A CN 1107514 C CN1107514 C CN 1107514C
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- rhizoma
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- lignum aquilariae
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Abstract
The present invention discloses a Chinese laxative medicinal preparation for Chinese medicine and a preparation method thereof. The Chinese laxative medicinal preparation for Chinese medicine can be widely applied to the treatment of laxative disease symptoms in the treatment based on differentiation of symptoms and signs. The Chinese laxative medicinal preparation for Chinese medicine comprises croton, Chinese eaglewood wood, chuanxiong rhizome, paris root, hemsleya, rhubarb, dried ginger and other Chinese herbal medicines, wherein the croton is used as a sovereign drug; the Chinese laxative medicinal preparation for Chinese medicine has a favorable laxative function through the compatibility of drugs and the processing of various drugs, the side effect of the croton is fundamentally eliminated, and the use is safe and convenient.
Description
The present invention relates to be used for by the tcm treatment according to syndrome differentiation theory medicine of " catharsis " treatment, specifically is the Chinese patent medicine of feedstock production with Chinese herbal medicine.The invention still further relates to the preparation method of this medicine.
" pain is then obstructed, and general rule is not bitterly " is the most important theories foundation that the traditional Chinese medical science is carried out determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs to the disease that the pain performance is arranged.All this, all with mediation, by being the main rule of treatment down.Many non-painful diseases are also built up in passages through which vital energy circulates or internal organs owing to QI and blood stasis, exopathogen in Chinese medical discrimination, treatment under needing to do to dredge, pursue.In the Chinese traditional treatment means, though but acupuncture, massage also dredging the meridian, operation QI and blood are arranged, the medicine catharsis is then more commonly used and more effective.Chinese herbal medicine catharsis method is usually used in attacking by stagnant, swings except that pathogenic heat.All damp and hot heresies are coalescent in the intestines and stomach, or the stagnant all diseases of the vital organs of the human body, all can adopt catharsis decree heresy to dispel and eutopic reduction.
Traditional Chinese medical science ancient books Zhang Zhongjing is shown " Medical Treasures of the Golden Chamber " secretary and is loaded with " sanwu beiji pill " side, is a tradition prescription of the traditional Chinese medical science " catharsis ".It consists of Fructus Crotonis, Radix Et Rhizoma Rhei, Rhizoma Zingiberis three herbal medicines, cures mainly " the sudden and violent all kinds of diseases and ailments of all trusted subordinate soldiers ".But should the side bigger because of contained Fructus Crotonis toxic and side effects, there have slightly in the use to be improper or careless, just let out excessively, the vigour of hurting sb.'s feelings is so it is quite few on top of to use this side person.Many doctors are forbidding to this side, shy away.It is comparable that yet the catharsis function of Fructus Crotonis does not have his medicine, always cures the monarch of tame prescription for each.Still can not effectively separate under the situation of effective ingredient in the Fructus Crotonis and toxic component in Modern Pharmaceutical Chemistry, by the process of preparing Chinese medicine processing of Chinese medicine and the compatibility of drugs of auxilliary restriction or checking relation in five elements mutually, subdue or make toxicity except that Fructus Crotonis, preserve its property of medicine, be real feasible innovative technology.
The object of the present invention is to provide a kind of Chinese medicine preparation that is used for traditional Chinese medical science catharsis, the disease that it does the catharsis treatment to all needs in the tcm treatment according to syndrome differentiation extensively is suitable for, and determined curative effect is reliable, and toxic and side effects is faint, and is safe and convenient to use.
Another object of the present invention provides the preparation method of this catharsis medicine.
Solution of the present invention is based on the understanding of motherland's medical science to the catharsis rule of treatment and all medicine property of medicine, through constantly test and improvement decades, keep Fructus Crotonis as monarch drug, by the process of preparing Chinese medicine processing of compatibility of drugs and multiple medicine, make catharsis agent of the present invention have good catharsis function and also eliminated toxic and side effects substantially.
The component of medicine of the present invention comprises following crude drug kind, and the consumption of each crude drug is with under the weight portion row: Fructus Crotonis 3-9 Lignum Aquilariae Resinatum 3-9 Rhizoma Chuanxiong 3-9 Rhizoma Paridis 3-9 Radix Hemsleyae Macrospermae 1-9 Radix Et Rhizoma Rhei 1-9 Rhizoma Zingiberis 1-9 Radix Platycodonis 1-9 Rhizoma Corydalis 3-9 Radix Glycyrrhizae 1-9 Fructus Amomi 3-9 Rhizoma Acori Graminei 3-9 Sanguis Draxonis 1-9 Radix Notoginseng 1-9 Radix Panacis Quinquefolii 3-9 Borneolum Syntheticum 0.3-3 Liquor Menthae Distillata 0.3-3 Mel 10-80
Wherein the consumption of Fructus Crotonis and Lignum Aquilariae Resinatum keeps roughly balance, Fructus Crotonis: Lignum Aquilariae Resinatum=1: 0.9-1.1
" Radix Hemsleyae Macrospermae ", Hemsleya amabilis Diels is the tuber of the little SHELIAN of cucurbitaceous plant.(seeing 355 pages of " Yunnan Chinese herbal medicine will " first volumes, Yunnan science and technology publishing house front page in August nineteen ninety)
" Liquor Menthae Distillata " sees 2650 pages of " Chinese medicine dictionary " volume two, and the Shanghai People's Press publishes.
Fructus Crotonis in the crude drug stagnates in order to assault fortified position brokenly, and tonneau closes key, removes the heavy cold of the vital organs of the human body, is each medicine it " monarch ".Lignum Aquilariae Resinatum removes bad odor, transfers all gas; The Rhizoma Chuanxiong activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain.Three medicines phase 5, logical all keys can be attacked and can be broken, and can manage it and can end, and can rise and can fall.The Rhizoma Paridis heat-clearing and toxic substances removing swings the long-pending logical stasis of blood; The Radix Hemsleyae Macrospermae heat-clearing and toxic substances removing, reducing swelling and alleviating pain; Radix Et Rhizoma Rhei is cleansed the intestines and stomach, removes the damp and hot of the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels; Rhizoma Zingiberis drives the cold-evil of all warps, harmonizing yingfen and weifen; The Radix Platycodonis lung qi dispersing eliminates the phlegm, the evacuation of pus sore-throat relieving; The slow all warps of Rhizoma Corydalis are pain, separates the poison of all diseases; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription return through; During the Fructus Amomi circulation of qi promoting was transferred, stomach function regulating was amusing; The Rhizoma Acori Graminei causing resuscitation with aromatic drugs, appetizing refreshment dehumidifying; The pain relieving of Sanguis Draxonis blood stasis removing is invigorated blood circulation and is cured the wound; The Radix Notoginseng stopping bleeding and removing blood stasis, subduing swelling and relieving pain; The Radix Panacis Quinquefolii boosting qi and nourishing yin relieves inflammation or internal heat and promotes the production of body fluid; The Borneolum Syntheticum refreshment of having one's ideas straightened out, clearing away heat to alleviate pain; The Liquor Menthae Distillata refreshing and detoxicating, a surname opens clearly thoroughly; Mel invigorating middle warmer emergency is moisturized detoxifcation, the mediation property of medicine.More than all medicines close ginseng, make a surname that is so incensed that who stagnates for a long time, the blood of the stasis of blood must be changed for a long time, mechanism of qi a surname is logical, blood vessels are in harmonious proportion, the stasis of blood is gone new life, all kinds of diseases and ailments spontaneous recovery.
It is as follows that each crude drug of said components is made medicine production method of the present invention.
One. the part medicine is concocted processing
Fructus Crotonis in the component, Rhizoma Paridis, 3 kinds of crude drug of Radix Et Rhizoma Rhei must use through concocting the back; Mel uses through the refining back; Rhizoma Chuanxiong is concocted the back by following method and is used, and also can give birth to usefulness; Other medicines can be given birth to usefulness, also can concoct the back by traditional Chinese medical science traditional method and use.
1. the concocting method of Fructus Crotonis: get Fructus Crotonis and be soaked in to take out after Mi Shuizhong 6-12 hour and dry, repeat the process totally 3 times of " soaking-dry ".Replace meter process of water repetition " soaking-dry " totally 3 times with Lignum Aquilariae Resinatum water more afterwards.
2. the concocting method of Rhizoma Chuanxiong: Rhizoma Chuanxiong power is broken into fine powder, by weight 1: 1 with the Fel Sus domestica mix homogeneously, dry.
3. the concocting method of Rhizoma Paridis: select the Rhizoma Paridis of perennial hypertrophy, be ground into fine powder, soak into, put in the appropriate containers sealing and preserve the 1-3 month, dry, put food steamer again and steamed 30 minutes-2 hours, dry through water vapour with the 50-60 degree Chinese liquor of grain brew.
4. the concocting method of Radix Et Rhizoma Rhei: Radix Et Rhizoma Rhei powder is broken into fine powder, soaks into, keep 2-5 day with the 50-60 degree Chinese liquor of grain brew, dry or fry do standby.
Two. produce unguentum
Each medicine pulverize separately that will be except that Mel, it is standby to cross the 100-120 mesh sieve.
Mel is refined, behind fire, add processed fructus crotonis, Lignum Aquilariae Resinatum, gallbladder Rhizoma Chuanxiong, system Rhizoma Paridis, Radix Hemsleyae Macrospermae, Radix et Rhizoma Rhei (processed), Rhizoma Zingiberis, Radix Platycodonis and each drug powder of Rhizoma Corydalis immediately, mixing and stirring, add Radix Glycyrrhizae, Fructus Amomi, Rhizoma Acori Graminei, Sanguis Draxonis, Radix Notoginseng, Radix Panacis Quinquefolii, Borneolum Syntheticum and Liquor Menthae Distillata drug powder again, further mix to rub and mix evenly, make the cream block, the preparation that further is processed into powder and other dosage forms after 7-10 days is preserved in sealing.
Here said processed fructus crotonis, gallbladder Rhizoma Chuanxiong, system Rhizoma Paridis, Radix et Rhizoma Rhei (processed) are meant the product by operation one described concocting method gained.
Three. produce powder
With above-mentioned processed with honey cream piece airing or dry, pulverize, cross the 100-120 mesh sieve, be the powder finished product, take after the packing.
Four. produce other dosage form
With above-mentioned technology two or three unguentum of being produced or powder is raw material, can further manufacture dosage forms such as water pill, honeyed pill, tablet, capsule, granular pattern electuary, oral liquid by normally used pharmaceutical technique method of modern times.Made pill claims " 99 well-informed ball ".
More than various dosage forms adult oral doses be equivalent to crude drug 1.0 grams approximately every day, divides and takes for 1-3 time, generally logotype is 3 days.Change into afterwards and taking 3-7 day 1 time, each oral dose is equivalent to crude drug 0.3-0.5 gram approximately, takes continuously 1-2 month.
Clinical drug application result of the present invention shows following advantage:
1. indication is widely arranged, especially the chronic persistent disease is had better curative effect.
It is damp and hot that medicine of the present invention is widely used in cold of dispeling the upper, middle and lower three warmers, shines human body life, and diseases such as acute/chronic gastroenteritis, colitis, appendicitis, cholecystitis, urinary system calculus, acute/chronic bronchitis are all had significant curative effect; Osteomyelitis, hyperosteogeny, hypertension, hyperlipidemia, diabetes, obesity etc. also there is curative effect preferably.Using pill of the present invention treats above-mentioned disease patient's 1338 examples and obtains definite curative effect.
2. higher safety is arranged.Carry out nearly 100 times concocting experiment by method of the present invention to giving birth to Fructus Crotonis, all removed the toxicity of Fructus Crotonis effectively.In therapeutic process, do not have 1 example and poison above-mentioned 1338 routine various diseases patients.
The invention will be further described by the following examples.
Embodiment 1 produces unguentum
1. select medicine and its weight for use: Fructus Crotonis 900g Lignum Aquilariae Resinatum 900g Rhizoma Chuanxiong 900g Rhizoma Paridis 900g Radix Hemsleyae Macrospermae 900g Radix Et Rhizoma Rhei 900g Rhizoma Zingiberis 900g Radix Platycodonis 900g Rhizoma Corydalis 900g Radix Glycyrrhizae 900g Fructus Amomi 900g Rhizoma Acori Graminei 900g Sanguis Draxonis 900g Radix Notoginseng 900g Radix Panacis Quinquefolii 900g Borneolum Syntheticum 300g Liquor Menthae Distillata 300g Mel 6600g
2. Fructus Crotonis, Rhizoma Chuanxiong, Rhizoma Paridis, Radix Et Rhizoma Rhei are concocted:
(1) Fructus Crotonis is put in the washing water of rice to soak to take out after 12 hours and dried the process of repetition " soaking-dry " totally 3 times.Replace meter process of water repetition " soaking-dry " totally 3 times with Lignum Aquilariae Resinatum water afterwards.Under sunny weather, can finish in continuous 6 days.
The preparation method of washing water of rice: get rice 1800 gram (be about Fructus Crotonis weight 2 times) and place 3600 milliliters of clear water (be about rice weight 1.5 times), stir about 10 minutes goes the rice water intaking standby.This is the consumption that once soaks.
The preparation method of Lignum Aquilariae Resinatum water: other gets Chinese medicine Lignum Aquilariae Resinatum 270 gram (be about Fructus Crotonis weight 0.3 times), with 5-8 doubly (weight) hot boiled water brewed 3 hours, go the Lignum Aquilariae Resinatum water intaking standby.This is the consumption that once soaks.
(2) Rhizoma Chuanxiong was pulverized 120 mesh sieves, its powder and heavy Fel Sus domestica mixing such as grade dry standby.
(3) select the Rhizoma Paridis of perennial hypertrophy, pulverized 120 mesh sieves and become fine powder, soak into, put in the wide-mouth vial sealing and preserve February with 60 degree Chinese liquor of grain brew, take out dry standby.
(4) Radix Et Rhizoma Rhei is put in the glass jar, spent Chinese liquor with 50 of grain brew and soak into, kept 3, fry dried standby.
3. each medicine pulverize separately that will be except that Mel is crossed 120 mesh sieves.Mel is refined, behind fire, add Fructus Crotonis, Lignum Aquilariae Resinatum, Rhizoma Chuanxiong, Rhizoma Paridis, Radix Hemsleyae Macrospermae, Radix Et Rhizoma Rhei, Rhizoma Zingiberis, Radix Platycodonis and Rhizoma Corydalis drug powder immediately, mixing and stirring, add Radix Glycyrrhizae, Fructus Amomi, Rhizoma Acori Graminei, Sanguis Draxonis, Radix Notoginseng, Radix Panacis Quinquefolii, Borneolum Syntheticum and Liquor Menthae Distillata drug powder again, further mix to rub and mix evenly, make the cream block, sealing is preserved.
Present embodiment uses crude drug 20,700 grams altogether, makes about 19,665 grams of unguentum.This unguentum can be treated usefulness by oral work, preserves more than 7 days but be more suitable for sealing, makes raw material, further is processed into the preparation of powder and other dosage forms.
Embodiment 2 produces powder
1. select medicine and its weight for use: Fructus Crotonis 310g Lignum Aquilariae Resinatum 300g Rhizoma Chuanxiong 300g Rhizoma Paridis 900g Radix Hemsleyae Macrospermae 100g Radix Et Rhizoma Rhei 100g Rhizoma Zingiberis 100g Radix Platycodonis 100g Rhizoma Corydalis 500g Radix Glycyrrhizae 200g Fructus Amomi 300g Rhizoma Acori Graminei 300g Sanguis Draxonis 900g Radix Notoginseng 900g Radix Panacis Quinquefolii 300g Borneolum Syntheticum 30g Liquor Menthae Distillata 30g Mel 2600g
2. processing and fabricating method: above-mentioned each medicine concocted by the method for embodiment 1 be processed into unguentum, sealing is preserved to open after 10 days and is dried, and crushing screening is finished product powder.
Present embodiment uses crude drug 8,270 grams altogether, makes about 7,856 grams of finished product powder.
Embodiment 3 produces tablet
1. select medicine and its weight for use: Fructus Crotonis 900g Lignum Aquilariae Resinatum 900g Rhizoma Chuanxiong 300g Rhizoma Paridis 900g Radix Hemsleyae Macrospermae 300g Radix Et Rhizoma Rhei 100g Rhizoma Zingiberis 100g Radix Platycodonis 600g Rhizoma Corydalis 600g Radix Glycyrrhizae 120g Fructus Amomi 400g Rhizoma Acori Graminei 600g Sanguis Draxonis 900g Radix Notoginseng 900g Radix Panacis Quinquefolii 900g Borneolum Syntheticum 100g Liquor Menthae Distillata 80g Mel 3600g
2. processing and fabricating method: above-mentioned each medicine concocted by the method for embodiment 1 be processed into unguentum, sealing is preserved after 7 days and is opened, and further rubs and mixes evenly, and tabletting airing or oven dry are finished tablet.Also can wrap with sugar-coat.
Present embodiment uses crude drug 12,300 grams altogether, makes 35,055 in tablet, and every contains effective composition and is equivalent to crude drug 0.33 gram approximately.
Embodiment 4 produces capsule
1. select medicine and its weight for use: Fructus Crotonis 600g Lignum Aquilariae Resinatum 640g Rhizoma Chuanxiong 600g Rhizoma Paridis 900g Radix Hemsleyae Macrospermae 300g Radix Et Rhizoma Rhei 500g Rhizoma Zingiberis 600g Radix Platycodonis 900g Rhizoma Corydalis 600g Radix Glycyrrhizae 600g Fructus Amomi 900g Rhizoma Acori Graminei 900g Sanguis Draxonis 100g Radix Notoginseng 100g Radix Panacis Quinquefolii 900g Borneolum Syntheticum 30g Liquor Menthae Distillata 30g Mel 5000g
2. processing and fabricating method: above-mentioned each medicine concocted by the method for embodiment 1 be processed into unguentum, sealing is preserved after 8 days and is opened, and oven dry row is again pulverized, and crosses 120 mesh sieves, divides the encapsulated finished product that is.
Present embodiment uses crude drug 14,200 gram altogether, makes about 13,000 grams of dry cream powder, divides 28,500 of No. 0 capsules of packing into, and every contains effective composition and is equivalent to crude drug 0.5 gram approximately.
Claims (7)
1. medicine that is used for traditional Chinese medical science catharsis, it is characterized in that, it is the medicament of being made by the following weight proportion raw material, and Fructus Crotonis 3-9 Lignum Aquilariae Resinatum 3-9 Rhizoma Chuanxiong 3-9 Rhizoma Paridis 3-9 Radix Hemsleyae Macrospermae 1-9 Radix Et Rhizoma Rhei 1-9 Rhizoma Zingiberis 1-9 Radix Platycodonis 1-9 Rhizoma Corydalis 3-9 Radix Glycyrrhizae 1-9 Fructus Amomi 3-9 Rhizoma Acori Graminei 3-9 Sanguis Draxonis 1-9 Radix Notoginseng 1-9 Radix Panacis Quinquefolii 3-9 Borneolum Syntheticum 0.3-3 Liquor Menthae Distillata 0.3-3 Mel 10-80 is Fructus Crotonis wherein: Lignum Aquilariae Resinatum=1: 0.9-1.1
2. medicine according to claim 1 is characterized in that, said medicament is a said dosage form on any pharmaceutics.
3. medicine according to claim 1 is characterized in that, used Fructus Crotonis is " to soak-dry " 3 times through Mi Shui, and reuse Lignum Aquilariae Resinatum water " soaks-dry " 3 times.
4. medicine according to claim 1 is characterized in that used Rhizoma Chuanxiong power is broken into fine powder, and 1: 1 and Fel Sus domestica mixing dry by weight.
5. medicine according to claim 1 is characterized in that used Rhizoma Paridis is ground into fine powder, soaks into the 50-60 degree Chinese liquor of grain brew, and the 1-3 month is preserved in sealing, steams through water vapour again, dries.
6. medicine according to claim 1 is characterized in that, used Radix Et Rhizoma Rhei soaks into the 50-60 degree Chinese liquor of grain brew, keeps 2-5 and dries after day or fry dried.
7. prepare the method for the described medicine of claim 1, it is characterized in that,
(1) by the mode of claim 3-6 used Fructus Crotonis, Lignum Aquilariae Resinatum, Rhizoma Chuanxiong, Rhizoma Paridis are concocted;
(2) Mel is refined, behind fire, add Fructus Crotonis, Lignum Aquilariae Resinatum, Rhizoma Chuanxiong, Rhizoma Paridis, Radix Hemsleyae Macrospermae, Radix Et Rhizoma Rhei, Rhizoma Zingiberis, Radix Platycodonis and Rhizoma Corydalis drug powder, stir, add Radix Glycyrrhizae, Fructus Amomi, Rhizoma Acori Graminei, Sanguis Draxonis, Radix Notoginseng, Radix Panacis Quinquefolii, Borneolum Syntheticum and Liquor Menthae Distillata drug powder again, further rub and mix evenly, sealing was preserved 7-10 days;
(3) will seal the paste unlatching of preserving and dry, crushing screening is made powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00107319A CN1107514C (en) | 2000-05-10 | 2000-05-10 | Laxative and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00107319A CN1107514C (en) | 2000-05-10 | 2000-05-10 | Laxative and its preparation |
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| Publication Number | Publication Date |
|---|---|
| CN1322536A CN1322536A (en) | 2001-11-21 |
| CN1107514C true CN1107514C (en) | 2003-05-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN00107319A Expired - Fee Related CN1107514C (en) | 2000-05-10 | 2000-05-10 | Laxative and its preparation |
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| CN (1) | CN1107514C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5187802B2 (en) * | 2006-01-18 | 2013-04-24 | 公益財団法人名古屋産業科学研究所 | Laxative and food containing the same |
| JP5066394B2 (en) * | 2007-06-11 | 2012-11-07 | アピ株式会社 | Method for extracting genkwanin 5-O-β-primeveroside |
| CN110420309B (en) * | 2019-05-31 | 2023-05-02 | 天祝藏族自治县藏医药开发研究所 | Anti-inflammatory analgesic Tibetan medicine pill for treating chronic appendicitis |
| CN113730526A (en) * | 2021-09-15 | 2021-12-03 | 陈宝洪 | Formula for preventing and treating digestive system diseases |
| CN113713038A (en) * | 2021-09-15 | 2021-11-30 | 陈宝洪 | Purgation medicine and preparation method thereof |
| CN113577235A (en) * | 2021-09-17 | 2021-11-02 | 陈宝洪 | Traditional Chinese medicine composition compound for treating practical symptoms |
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