CN110732012A - A Chinese medicinal composition for treating hepatitis, and its preparation method - Google Patents

A Chinese medicinal composition for treating hepatitis, and its preparation method Download PDF

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CN110732012A
CN110732012A CN201911185299.1A CN201911185299A CN110732012A CN 110732012 A CN110732012 A CN 110732012A CN 201911185299 A CN201911185299 A CN 201911185299A CN 110732012 A CN110732012 A CN 110732012A
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王同生
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Abstract

The invention relates to the field of traditional Chinese medicine, in particular to traditional Chinese medicine compositions for treating hepatitis and a preparation method thereof, the traditional Chinese medicine compositions comprise, by weight, 10-100 parts of black ants, 10-100 parts of swertia mileensis, 10-100 parts of phyllanthus urinaria, 10-100 parts of lucid ganoderma, 10-100 parts of radix sophorae flavescentis, 10-100 parts of sophora alopecuroides, 10-100 parts of polyporus umbellatus, 10-100 parts of liquorice, 10-100 parts of fructus trichosanthis, 10-100 parts of red ginseng, 10-100 parts of astragalus membranaceus, 10-100 parts of radix curcumae, 10-100 parts of curcuma longa, 10-100 parts of turtle shell, 10-100 parts of rhizoma sarcandrae chinensis, 10-100 parts of curcuma zedoary, 10-100 parts of frankincense, 10-100 parts of myrrh, 10-100 parts of pseudo-ginseng, 10-100 parts of bighead atractylodes rhizome, 10-100 parts of endothelium corneum gigeriae galli, 10-100 parts of hawthorn, 10-100 parts of cyperus rotundus, 10-100 parts of radix bupleuri, 10-100 parts of oyster and 10-100 parts of eupolyphaga.

Description

A Chinese medicinal composition for treating hepatitis, and its preparation method
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to traditional Chinese medicine compositions for treating hepatitis and a preparation method thereof.
Background
Hepatitis is a general term for liver inflammation, and generally refers to liver cell destruction caused by various pathogenic factors, such as viruses, bacteria, parasites, chemicals, poisons, drugs, alcohol, autoimmune factors, etc., liver function is damaged, and series of discomfort symptoms and abnormal liver function index are caused.
The hepatitis is divided into acute hepatitis and chronic hepatitis, the acute viral hepatitis is mainly caused by hepatropic hepatitis virus A, B, C, D, E, non-specific hepatropic viruses such as cytomegalovirus, Epstein-Barr virus, herpes simplex virus and the like can also cause the hepatitis, but the hepatitis is rare, while the chronic hepatitis B (hepatitis B for short) refers to the hepatitis B virus which is detected to be positive, the disease course is more than half a year or the disease date is not clear and the clinical symptoms of chronic hepatitis are symptoms such as hypodynamia, chilliness, nausea, abdominal distension, liver pain and the like.
Although the etiology of hepatitis is different, it has similar clinical manifestations, but the etiology, serology, damage mechanism, clinical diagnosis and treatment are different.
At present, a lot of medicines for treating acute hepatitis and chronic hepatitis are used in China, and in western medicines, nucleoside antiviral medicines are often used for treating hepatitis, but the medicine has large side effect, and patients are easy to generate drug resistance, and the treatment effect is poor. However, in the traditional Chinese medicines, the traditional Chinese medicines with good treatment effect are few, and the treatment effect of combining treatment and function recovery cannot be achieved.
Disclosure of Invention
The invention aims to solve the technical problem of providing kinds of treatment effects which can fundamentally realize the combination of treatment and function recovery.
The technical scheme for solving the technical problems is that traditional Chinese medicine compositions for treating hepatitis comprise, by weight, 10-100 parts of black ants, 10-100 parts of swertia mileensis, 10-100 parts of phyllanthus urinaria, 10-100 parts of lucid ganoderma, 10-100 parts of radix sophorae flavescentis, 10-100 parts of sophora alopecuroides, 10-100 parts of polyporus umbellatus, 10-100 parts of liquorice, 10-100 parts of fructus trichosanthis, 10-100 parts of red ginseng, 10-100 parts of astragalus membranaceus, 10-100 parts of radix curcumae, 10-100 parts of curcuma longa, 10-100 parts of turtle shell, 10-100 parts of rhizoma sarcandrae chinensis, 10-100 parts of curcuma zedoary, 10-100 parts of frankincense, 10-100 parts of myrrh, 10-100 parts of pseudo-ginseng, 10-100 parts of bighead atractylodes rhizome, 10-100 parts of endothelium corneum gigeriae galli, 10-100 parts of hawthorn, 10-100 parts of cyperus rotu.
steps, which comprise (by weight parts) Formica fusca 30-80, swertia mileensis 30-80, cacumen Securinegae Suffruticosae 30-80, Ganoderma 30-80, radix Sophorae Flavescentis 30-80, herba Sophorae Alopecuroidis 30-80, Polyporus 30-80, radix Glycyrrhizae 30-80, fructus Piperis Longi 30-80, radix Ginseng Rubra 30-80, radix astragali 30-80, radix Curcumae 30-80, rhizoma Curcumae Longae 30-80, carapax Trionycis 30-80, rhizoma Sparganii 30-80, rhizoma Curcumae 30-80, Olibanum 30-80, Myrrha 30-80, radix Notoginseng 30-80, rhizoma Atractylodis Macrocephalae 30-80, endothelium corneum Gigeriae Galli 30-80, fructus crataegi 30-80, rhizoma Cyperi 30-80, radix bupleuri 30-80, Concha Ostreae 30-80, and Eupolyphaga Seu Steleophaga 30-80.
A method for preparing Chinese medicinal composition comprises the following steps:
s1, weighing groups of medicinal materials, a second group of medicinal materials and a third group of medicinal materials according to the formula of the Chinese medicinal composition;
group of medicinal materials including herba Swertiae Mileensis, cacumen Securinegae Suffruticosae, radix Sophorae Flavescentis, herba Sophorae Alopecuroidis, Polyporus and Glycyrrhrizae radix, the second group of medicinal materials including Atractylodis rhizoma, carapax Trionycis, fructus crataegi and rhizoma Cyperi, and the third group of medicinal materials including Formica Fusca, Ganoderma, fructus Piperis Longi, Ginseng radix Rubri, radix astragali, radix Curcumae, Curcuma rhizome, rhizoma Sparganii, Curcumae rhizoma, Olibanum, Myrrha, Notoginseng radix, Atractylodis rhizoma, endothelium corneum Gigeriae Galli, bupleuri radix, Concha Ostreae and Eupolyphaga Seu Steleophaga;
s2, decocting th medicinal materials in water, and concentrating and drying in the shade to obtain th medicinal preparation;
s3, respectively parching the second group of materials, and mixing to obtain a second preparation;
s4, mixing the th medicament, the second medicament and the third group of medicinal materials, and then sequentially crushing, grinding and sterilizing to obtain the traditional Chinese medicine composition.
In the step S1, genuine medicinal materials are selected and divided into three groups, namely, a decocting group, a stir-frying group and a raw group according to the medicinal principle of each medicinal material, and each group of medicinal materials are washed by clear water and dried for later use;
in step S2, decocting group of medicinal materials in water, and fully extracting effective components from the medicinal materials;
in step S3, the second group of herbs are respectively fried to make the properties of the herbs exert to the maximum;
in step S4, the th drug, the second drug and the third group of drugs are mixed, and then sequentially pulverized, ground and sterilized to prepare the traditional Chinese medicine composition.
, in step S2, the decoction includes times of decoction, the second decoction and the third decoction,
the th decoction is prepared by soaking group of medicinal materials in water for 20-60min according to the weight ratio of 1 (2-4) to water, heating to boil, decocting at 50-100 deg.C until the medicinal liquid is lost (1/3) - (1/2), filtering to obtain th filtrate, and collecting th residue;
the second decoction is to add water in the original weight ratio into th residue, to be decocted at 50-100 ℃ after heating and boiling until the liquid medicine is lost (1/3) - (1/2), to be filtered to obtain a second filtrate, and to collect the second residue;
repeating the second decocting step in the third decocting step to obtain a third filtrate;
mixing the th filtrate, the second filtrate and the third filtrate, decocting at 50-100 deg.C, concentrating, and drying in the shade to obtain th medicinal preparation.
The decocting of the medicinal materials is carried out for three times, water in the original weight ratio is added when the medicinal liquid is lost (1/3) - (1/2) each time, the decocting is carried out continuously under the slow fire at 50-100 ℃, the step is repeated, and finally the filtrates of the three times are mixed and continuously concentrated under the slow fire at 50-100 ℃, so that the method not only can fully extract the effective components in the medicinal materials, but also can ensure that the effective components are enriched at the treatment temperature of 50-100 ℃, and further the th medicament is obtained.
, in step S3, parching the second group of herbs at 50-150 deg.C to light yellow.
The atractylodes macrocephala koidz, the turtle shell, the hawthorn and the monkshood in the second group of medicinal materials are all medicinal materials for stir-frying, and clinical test data show that the four medicinal materials are combined for use after being stir-fried, so that the medicinal properties of the medicinal materials can be exerted to the maximum.
, in step S4, the ground powder is sieved by a 200-mesh sieve with 150 meshes.
The th medicament, the second medicament and the third group of medicinal materials are mixed and crushed and ground through a 150-mesh and 200-mesh sieve, so that the absorption rate of the traditional Chinese medicine composition can be improved.
, in step S4, the sterilization method is to use ultraviolet lamp radiation for 30-60 min.
The ground traditional Chinese medicine composition is subjected to ultraviolet lamp radiation treatment, so that the contact area of ultraviolet light and the traditional Chinese medicine composition can be increased, and the sterilization effect can be achieved in a short time.
application of Chinese medicinal composition in preparing medicine for treating hepatitis.
The Chinese medicinal composition can be used for preparing medicines for treating various hepatitis.
, the medicine is tablet, pill, granule or capsule.
When preparing the hepatitis medicine, the medicine can be prepared into tablets, pills, granules or capsules.
Pharmacological analysis of the traditional Chinese medicine composition:
the black ant has mild nature, and kinds of ant toxin are contained in the body of the black ant, and the toxin is a killer of hepatitis B virus and has the function of controlling and killing the hepatitis B virus.
And (3) green leaf gall: it is also called as meridian tropism, gallbladder meridian tropism, liver meridian, bladder meridian, cold nature and bitter taste, and has the functions of clearing away liver heat, promoting bile flow, clearing away heat and promoting diuresis.
Phyllanthus urinaria L: has effects in suppressing hyperactive liver, clearing away heat, promoting diuresis, and removing toxic substances, and the extract of Phyllanthus urinaria has effects in inhibiting acute hepatitis B virus infection, directly resisting hepatitis B virus, and regulating immune system.
Ganoderma lucidum: has effects of promoting regeneration of human body cells, removing toxic substance, improving immunity, and controlling and repairing canceration of human liver cells.
Matrine and aloperine: has antiviral, liver cell membrane stabilizing, liver cell apoptosis blocking, liver microcirculation improving, liver cell regeneration promoting, and hepatitis B virus replication and immunity inhibiting effects.
And (3) polyporus umbellatus: has diuretic, antitumor and immunity enhancing effects.
Licorice root: the active ingredients of the liquorice are triterpenoid saponin and flavonoid compounds such as glycyrrhizic acid and liquiritin, and have strong pharmacological activity in the aspects of anti-inflammation, antioxidation, anticancer, liver protection and the like.
Repeating the steps of: is slightly cold in nature, and has the effects of clearing away heat and toxic materials, relieving swelling and pain, and cooling liver to arrest convulsion.
Red ginseng: is a cooked product of ginseng, has the functions of invigorating primordial qi, tonifying spleen and lung, promoting the production of body fluid and soothing the nerves, has the characteristics of warmer property, large and powerful fire and strong efficacy, and is better for invigorating primordial qi, restoring yang and rescuing from collapse, and tonifying qi and controlling blood.
Astragalus root: enhancing immunity, promoting urination, and resisting aging.
Turmeric root-tuber: enters heart, lung and liver meridians and is mainly used for hepatitis, cirrhosis and cholecystitis.
Curcumin: has antitumor, antimutagenic, antibacterial, antiviral, antioxidant, and neuroprotective effects.
Turtle shell: has effects of softening and resolving hard mass.
Three shuttles: break blood and move qi, resolve food stagnation and alleviate pain.
Zedoary turmeric: pungent and bitter in flavor and warm in nature, entering liver and spleen meridians; has effects in promoting qi circulation, resolving stagnation, removing blood stasis, and relieving pain.
Frankincense: has obvious pain relieving effect and stronger bacteriostasis effect on various antibiotics.
Myrrh: promoting blood circulation, relieving pain, eliminating swelling, and promoting granulation.
Pseudo-ginseng: stop bleeding, dispel blood and relieve pain.
White atractylodes rhizome: being bitter, warm, pungent and drastic in property, it has the actions of drying dampness, resolving turbidity and alleviating pain.
Endothelium corneum gigeriae galli: sweet in taste and neutral in nature, enters spleen, stomach, small intestine and bladder channels, and has the effects of tonifying spleen, clearing heat, dredging collaterals, regulating qi and the like.
Hawthorn fruit: has effects of reducing blood lipid, lowering blood pressure, tonifying heart, and resisting arrhythmia, and is also effective in invigorating spleen, stimulating appetite, promoting digestion, and promoting blood circulation for removing blood stasis.
Cyperus rotundus: can be used for treating stagnation of qi due to depression of the liver, chest, hypochondrium, abdominal distention and pain, and dyspepsia.
Bupleurum root: slightly cold in nature, bitter and pungent in flavor, entering liver and gallbladder meridians, and has the effects of soothing liver, promoting bile flow, dispelling qi, resolving stagnation and dissipating fire.
Oyster shell: it enters liver, gallbladder and kidney meridians, and liver wind-extinguishing herbs.
B, ground beetle: entering liver meridian, it is indicated for swelling and pain of liver and spleen, lumbar muscle strain and sprain caused by blood stasis.
Compared with the prior art, the traditional Chinese medicine composition for treating hepatitis has the beneficial effects that:
the traditional Chinese medicine composition takes black ants, phyllanthus urinaria, radix curcumae, turtle shells, cyperus rotundus and radix bupleuri as monarch drugs according to a monarch, minister, assistant and guide traditional Chinese medicine compatibility concept, takes black ants as representatives to mainly control and kill hepatitis B viruses, simultaneously takes nutrient components of the black ants as monarch drugs after being dried, absorbed and stored, and synthesizes various vitamins required by human bodies through livers (in the process of absorbing, storing and synthesizing vitamins by the livers, very unfavorable survival and replication environments can be generated for the hepatitis B viruses), the liver cells are surrounded by drugs for controlling and killing the hepatitis B viruses for a long time, and the drugs can repair damaged liver cells and provide sufficient nutrition for the livers to store, so after taking the medicine containing the traditional Chinese medicine composition, the hepatitis B viruses can be automatically discharged from liver , the regeneration and detoxification efficacies of lucid ganoderma lucidum, sophora alopecuroide, red ginseng, turmeric and sanshou as adjuvant drugs, have the regeneration and detoxification efficacies of human body cells, can block the spontaneous hepatic microcirculation of liver cells, can synergistically promote the regeneration of liver cells, inhibit the replication of gallbladder, inhibit the liver, inhibit the replication of gallbladder, transfer of gallbladder, and promote the liver, inhibit the liver, promote the proliferation of chicken liver, promote the proliferation of chicken, promote the liver to restore the liver, promote the liver to promote the regeneration of chicken, promote the liver to promote the regeneration of the liver to promote the regeneration of chicken, promote the liver to promote the regeneration of.
Detailed Description
It is noted that the following detailed description is exemplary and is intended to provide further explanation of the invention at unless otherwise indicated.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present application. As used herein, the singular forms also include the plural forms unless the context clearly dictates otherwise, and further, it is understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of the stated features, steps, operations, devices, components, and/or combinations thereof.
Hereinafter, embodiments of the present invention will be described in detail. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.
The parts of the examples which are not specified in specific conditions were carried out according to conventional conditions or conditions recommended by the manufacturer, and the reagents or equipment used therefor which are not specified by the manufacturer are conventional products which are commercially available, and 1 part in the examples means 1 g.
Example 1
Selecting genuine medicinal materials, respectively washing with clear water and drying in the air, weighing groups of medicinal materials including mile swertia herb 10 parts, phyllanthus urinaria 10 parts, sophora flavescens 10 parts, sophora alopecuroides 10 parts, polyporus umbellatus 10 parts and liquorice 10 parts, adding water according to the proportion of 1:2 to soak for 20min, then heating and boiling, decocting at 50 ℃ until the liquid medicine is lost 1/3, filtering to obtain filtrate, collecting residues, supplementing water in the residues according to the original weight ratio, heating and boiling, decocting at 50 ℃ until the liquid medicine is lost 5, filtering to obtain second filtrate, collecting second residues, repeating the step of decocting for the second time to obtain third filtrate, finally mixing filtrate, second filtrate and third filtrates, decocting and concentrating at 50 ℃ in the shade to obtain medicament, weighing 10 parts of bighead atractylodes rhizome, turtle shell 10 parts, hawthorn 10 parts, monkshood 10 parts, mixing 10 parts of astragalus root and myrrh, grinding 10 parts of astragalus root, 10 parts of curcuma, 10 parts of astragalus root, 10 parts of black sesame, 10 parts of radix curcuma, 10 parts of astragalus root, myrrh, 10 parts of astragalus root, myrrh, 10 parts of astragalus root and 10 parts of ground by using 10-7-element radiation, 10-7-10-7-mesh radiation, 10-three-mesh radiation, 10-mesh radiation, 10-mesh grinding and.
Example 2
Selecting genuine medicinal materials, respectively washing with clear water and drying in the air, weighing groups of medicinal materials of 30 parts of swertia mileensis, 30 parts of phyllanthus urinaria, 30 parts of sophora flavescens, 30 parts of sophora alopecuroides, 30 parts of grifola and 30 parts of liquorice, adding water according to the proportion of 1:4 to soak for 60min, then heating and boiling, decocting at 100 ℃ until the liquid medicine is lost 1/2, filtering to obtain filtrate, collecting residues, supplementing water in the original weight ratio to residues, heating and boiling, decocting at 100 ℃ until the liquid medicine is lost 1/2, filtering to obtain second filtrate, collecting second residues, repeating the step of decocting for the second time to obtain third filtrate, finally mixing filtrate, second filtrate and third filtrates, decocting and concentrating at 100 ℃ in the shade to obtain medicament, weighing 30 parts of atractylodes macrocephala second group of atractylis ovata, 30 parts of hawthorn, 30 parts of aconite, mixing with 30 parts of astragalus membranaceus, 30min, 30 parts of curcuma, 30 parts of astragalus membranaceus, 30 parts of curcuma, 30 parts of radix curcuma, 30 parts of ground by using an ultraviolet radiation, 30-7-membered lamp, 30-year-30-fried traditional Chinese medicine, 30-fried traditional Chinese medicine, ground three groups of ground traditional Chinese medicine after grinding, myrrh and 30-element medicine, 30-trogopteres, 30-trogopterus.
Example 3
Selecting genuine medicinal materials, respectively washing with clear water and drying in the air, weighing groups of medicinal materials including mile swertia herb 80 parts, phyllanthus urinaria 80 parts, sophora flavescens 80 parts, sophora alopecuroides 80 parts, polyporus umbellatus 80 parts and liquorice 80 parts, adding water according to the proportion of 1:4 to soak for 60min, then heating and boiling, decocting at 80 ℃ until the liquid medicine is lost 1/2, filtering to obtain filtrate, collecting residues, supplementing water in the residues according to the original weight ratio, heating and boiling, decocting at 80 ℃ until the liquid medicine is lost 5, filtering to obtain second filtrate, collecting second residues, repeating the step of decocting for the second time to obtain third filtrate, finally mixing filtrate, second filtrate and third filtrates, decocting and concentrating at 80 ℃ in the shade to obtain medicament, weighing 80 parts of bighead atractylodes rhizome, 80 parts of turtle shell, 80 parts of hawthorn, 80 parts of monkshood, respectively turning over to be yellowish at 100 ℃, mixing 80 min, drying in the shade to obtain 80 parts of astragalus root, 80 parts of curcuma rhizome, 80 parts of curcuma zedoary, 80 parts of astragalus root 80, 80 parts of astragalus root of ground into 80, 80 parts of black ginseng, 80 parts of astragalus root 80, myrrh, 80 parts of astragalus root 80, myrrh, 80-mesh traditional Chinese-ground, ground into powder, ground into.
Example 4
Selecting genuine medicinal materials, respectively washing with clear water and drying in the air, weighing 100 parts of swertia mileensis, 100 parts of phyllanthus urinaria, 100 parts of sophora flavescens, 100 parts of sophora alopecuroides, 100 parts of grifola and 100 parts of liquorice, adding water according to the proportion of 1:4 to soak for 60min, heating and boiling, decocting at 100 ℃ until the liquid medicine is lost 1/2, filtering to obtain filtrate, collecting th residue, supplementing water in the original weight ratio to th residue, heating and boiling, decocting at 100 ℃ until the liquid medicine is lost 5, filtering to obtain , collecting second residue, repeating the step of decocting for the second time to obtain third filtrate, finally mixing filtrate, second filtrate and third filtrates, decocting and concentrating at 100 ℃ in the shade to obtain 1/2 medicinal preparation, weighing 100 parts of atractylodes macrocephala, 100 parts of turtle shell, 100 parts of hawthorn, 100 parts of monkshood, mixing 100 parts of astragalus root, 100 parts of curcuma, 100 parts of astragalus root, 100 parts of curcuma longa medicinal material, 100 parts of astragalus root, 100 parts of curcuma zedoary, 100 parts of astragalus root, 100 parts of curcuma aromatica, 100 parts of ground, 100 parts of ground with 100 parts of black ginseng, 100 parts of ground, 100 parts of astragalus root, 100 parts of ground with 100-fried astragalus root, 100-element lamp, 100-mesh lamp, myrrh.
Comparative example
The traditional Chinese medicine for treating chronic hepatitis comprises the following raw materials of 20 parts of artemisia capillaries, 6 parts of subprostrate sophora, 5 parts of polygonum cuspidatum, 6 parts of swertia mileensis, 5 parts of broadleaf holly leaf, 2 parts of rhizoma sparganii, 6 parts of dandelion, 8 parts of radix scrophulariae, 6 parts of gallnut, 10 parts of platycodon grandiflorum, 6 parts of polygonum multiflorum, 2 parts of muskroot-like semiaquilegia root, 6 parts of dark plum fruit, 8 parts of codonopsis pilosula, 5 parts of golden cypress, 9 parts of photinia serrulata leaf and 4 parts of platycladi seed.
The results of treatment courses of 7 days after which the results of treatment were compared with those of the control example 2 in 50 patients with chronic hepatitis shown in Table 1 below.
Table 1 comparison of the therapeutic effects of example 2 and the control
Classes of Chinese herbs Number of examples Healing examples Working examples Examples of invalidity
Example 2 50 46 3 1
Comparative example 50 41 6 3
As can be seen from table 1, the cure rate of example 2 is 92%, the ineffective rate is not 2%, and the cure rate of the control example is 82%, and the ineffective rate is 6%, so that the cure rate of the example in treating chronic hepatitis diseases is higher than that of the control example, and the ineffective rate is lower than that of the control example, therefore, the traditional Chinese medicine composition of the example has a better effect in treating chronic hepatitis diseases than that of the control example, and the higher the glutamic-pyruvic transaminase, glutamic-oxalacetic transaminase, total bilirubin and indirect bilirubin are, the better the treatment effect of the traditional Chinese medicine composition is.
Typical cases are:
case 1: liu Yi, male and 52 years old, this patient got a diagnosis in his hospital of the people in the area of Netherlands in 8 months of 2009 due to symptoms such as abdominal distension, weakness, yellow urine, etc., and it was diagnosed as hepatitis B, which belongs to three positive, glutamic-pyruvic transaminase, glutamic-oxalacetic transaminase, total bilirubin, indirect bilirubin and hepatitis B virus are all higher. The pill of the traditional Chinese medicine composition prepared in the embodiment 1 is taken 2 times a day, 10g of the pill each time, 3 courses of treatment are taken, the big three positive is changed into the small two positive, the glutamic-pyruvic transaminase, the glutamic-oxalacetic transaminase and the total bilirubin are all reduced to the normal range, and the indirect bilirubin and the hepatitis B virus are all reduced to the normal range.
Case 2: zhangzhi, male, 60 years old, the patient was diagnosed with ascites due to cirrhosis in 2008 due to symptoms such as lack of strength, abdominal distension, emaciation, oliguria, etc., the capsule of the traditional Chinese medicine composition prepared in the embodiment 3 was taken 2 times a day at a dose of 10g each time for 3 courses of treatment, and the symptoms such as lack of effusion in abdominal cavity, strength lack of strength, abdominal distension, etc. were almost completely eliminated in B-ultrasonography.
Case 3: plum, male and 58 years old, the patient is diagnosed with hepatosplenomegaly in 2013 due to symptoms such as hypodynamia, nausea, vomiting, continuous abdominal distension, dark complexion and the like, the capsule of the traditional Chinese medicine composition prepared in the embodiment 4 is taken for 3 treatment courses at a dose of 10g each time 2 times a day, the B-ultrasonic examination is matched with liver function examination and blood routine examination, the hepatosplenomegaly symptom disappears, and various indexes such as glutamic-pyruvic transaminase and glutamic-oxalacetic transaminase are normal.
Case 4: wangzhi, female, 55 years old, patients were diagnosed with hepatitis B, glutamic-pyruvic transaminase, glutamic-oxalacetic transaminase, total bilirubin, indirect bilirubin and hepatitis B virus in 2015 due to upper abdominal discomfort, liver pain and hypodynamia, and the pills of the traditional Chinese medicine composition prepared in the embodiment 2 were taken 2 times a day at a dose of 10g each time for 3 courses of treatment, wherein the glutamic-pyruvic transaminase, the glutamic-oxalacetic transaminase and the total bilirubin are all reduced to normal ranges, and other symptoms are basically disappeared.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (9)

10-100 parts of black ants, 10-100 parts of swertia mileensis, 10-100 parts of phyllanthus urinaria, 10-100 parts of ganoderma lucidum, 10-100 parts of radix sophorae flavescentis, 10-100 parts of sophora alopecuroides, 10-100 parts of polyporus umbellatus, 10-100 parts of liquorice, 10-100 parts of fructus trichosanthis, 10-100 parts of red ginseng, 10-100 parts of astragalus membranaceus, 10-100 parts of radix curcumae, 10-100 parts of curcuma longa, 10-100 parts of turtle shell, 10-100 parts of sambucus chinensis, 10-100 parts of curcuma zedoary, 10-100 parts of frankincense, 10-100 parts of myrrh, 10-100 parts of pseudo-ginseng, 10-100 parts of bighead atractylodes rhizome, 10-100 parts of chicken gizzard membrane, 10-100 parts of hawthorn, 10-100 parts of cyperus rotundus, 10-100 parts of radix bupleuri, 10-100 parts of oyster and 10-100 parts of eupolyphaga.
2. The traditional Chinese medicine composition according to claim 1, which is characterized by comprising the following raw material components in parts by weight: 30-80 parts of black ants, 30-80 parts of swertia mileensis, 30-80 parts of phyllanthus urinaria, 30-80 parts of lucid ganoderma, 30-80 parts of radix sophorae flavescentis, 30-80 parts of sophora alopecuroides, 30-80 parts of polyporus umbellatus, 30-80 parts of liquorice, 30-80 parts of fructus trichosanthis, 30-80 parts of red ginseng, 30-80 parts of astragalus membranaceus, 30-80 parts of radix curcumae, 30-80 parts of curcuma longa, 30-80 parts of turtle shell, 30-80 parts of rhizoma sarcandrae, 30-80 parts of curcuma zedoary, 30-80 parts of frankincense, 30-80 parts of myrrh, 30-80 parts of pseudo-ginseng, 30-80 parts of bighead atractylodes rhizome, 30-80 parts of endothelium corneum gigeriae galli, 30-80 parts of hawthorn, 30-80 parts of cyperus rotundus, 30-80 parts.
3. The method of preparing the composition of any one of of claims 1-2, comprising the steps of:
s1, weighing groups of medicinal materials, a second group of medicinal materials and a third group of medicinal materials according to the formula of the Chinese medicinal composition;
group of medicinal materials including herba Swertiae Mileensis, cacumen Securinegae Suffruticosae, radix Sophorae Flavescentis, herba Sophorae Alopecuroidis, Polyporus and Glycyrrhrizae radix, the second group of medicinal materials including Atractylodis rhizoma, carapax Trionycis, fructus crataegi and rhizoma Cyperi, and the third group of medicinal materials including Formica Fusca, Ganoderma, fructus Piperis Longi, Ginseng radix Rubri, radix astragali, radix Curcumae, Curcuma rhizome, rhizoma Sparganii, Curcumae rhizoma, Olibanum, Myrrha, Notoginseng radix, Atractylodis rhizoma, endothelium corneum Gigeriae Galli, bupleuri radix, Concha Ostreae and Eupolyphaga Seu Steleophaga;
s2, decocting th medicinal materials in water, and concentrating and drying in the shade to obtain th medicinal preparation;
s3, respectively parching the second group of materials, and mixing to obtain a second preparation;
s4, mixing the th medicament, the second medicament and the third group of medicinal materials, and then sequentially crushing, grinding and sterilizing to obtain the traditional Chinese medicine composition.
4. The preparation method of claim 3, wherein the decoction comprises times of decoction, a second time of decoction and a third time of decoction in the step S2,
the th decoction is prepared by soaking group of medicinal materials in water for 20-60min according to the weight ratio of 1 (2-4) to water, heating to boil, decocting at 50-100 deg.C until the medicinal liquid is lost (1/3) - (1/2), filtering to obtain th filtrate, and collecting th residue;
the second decoction is to add water in the original weight ratio into th residue, to be decocted at 50-100 ℃ after heating and boiling until the liquid medicine is lost (1/3) - (1/2), to be filtered to obtain a second filtrate, and to collect the second residue;
repeating the second decocting step in the third decocting step to obtain a third filtrate;
mixing the th filtrate, the second filtrate and the third filtrate, decocting at 50-100 deg.C, concentrating, and drying in the shade to obtain th medicinal preparation.
5. The preparation method according to claim 3, wherein in step S3, the second group of herbs are respectively stir-fried at 50-150 ℃ until the second group of herbs are slightly yellow.
6. The method as claimed in claim 3, wherein in step S4, the ground material is sieved through a 150-mesh and 200-mesh sieve.
7. The method for preparing a pharmaceutical composition according to claim 3, wherein the sterilization is performed by UV irradiation for 30-60min in step S4.
8. Use of the Chinese medicinal composition of any one of claims 1-7 in the preparation of a medicament for the treatment of hepatitis.
9. Use according to claim 8, wherein the medicament is a tablet, a pill, a granule or a capsule.
CN201911185299.1A 2019-11-27 2019-11-27 A Chinese medicinal composition for treating hepatitis, and its preparation method Pending CN110732012A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1113779A (en) * 1994-06-17 1995-12-27 殷广全 Anti- hepatitis B preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1113779A (en) * 1994-06-17 1995-12-27 殷广全 Anti- hepatitis B preparation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
朱曾柏: "三七妙用", 《辽宁中医杂志》 *
钟有添等: "中医药治疗病毒性乙型肝炎研究进展", 《赣南医学院学报》 *

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