CN110693807B

CN110693807B - Skin bottom essence and preparation method thereof

Info

Publication number: CN110693807B
Application number: CN201911123232.5A
Authority: CN
Inventors: 何梦蝶
Original assignee: Zhejiang Inglemirepharm's Biotechnology Co ltd
Current assignee: Zhejiang Inglemirepharm's Biotechnology Co ltd
Priority date: 2019-11-16
Filing date: 2019-11-16
Publication date: 2022-07-19
Anticipated expiration: 2039-11-16
Also published as: CN110693807A

Abstract

The invention discloses a skin foundation essence and a preparation method thereof, belongs to the technical field of skin care products, and solves the problem that the prior art cannot well achieve anti-aging. The skin bottom essence is prepared from the following raw materials in percentage by weight: group A: 261-4% of glyceryl polyether; 1-4% of 1, 3-propylene glycol; 1-4% of humectant A: 1-4% of a humectant B: 1-4% of conditioner A: 1-4% of solvent A: 0.4-2% of 1, 2-hexanediol; 0.4-1% of p-hydroxyacetophenone; 0.05 to 0.5 percent of acryloyl dimethyl ammonium taurate/VP copolymer; 0.03-0.5% of xanthan gum; 0.05 to 0.15 percent of EDTA disodium; group B: 1-6% of butanediol; carbomer 0.05-0.4%; group C: 0.05 to 0.4 percent of tromethamine; group D containing the active substance, and the balance water. The invention realizes the whole anti-aging effect by stimulating self-activation and repair and simultaneously cooperating with strengthening the skin barrier.

Description

Skin bottom essence and preparation method thereof

Technical Field

The invention relates to the technical field of skin care products, and particularly relates to a skin bottom essence and a preparation method thereof.

Background

The essence is one of facial skin care products, and is an efficacy product with higher concentration after being used in toner and before being used in emulsion or cream. With the increase of age, the skin water-locking capacity is reduced to cause the reduction of skin water, meanwhile, the synthetic capacity of fibroblasts also gradually begins to decline, the synthesis of collagen and elastin is reduced, the skin gradually loses elasticity, and the skin aging phenomenon is presented; on the other hand, the oxidation resistance protection system can be weakened, further oxidation stress and cell damage are caused, and aging is accelerated.

Chinese patent with publication number CN103520017A discloses a composition for removing wrinkles, resisting aging, activating skin, repairing and whitening skin, which comprises the following components in percentage by weight: 15 to 30 percent of hyaluronic acid, 25 to 40 percent of collagen, 0.0001 to 0.0009 percent of recombinant human epidermal growth factor and 5 to 20 percent of glycerol.

In the prior art, only the moisturizing component, the collagen and the recombinant human epidermal growth factor exist, the composition has simple components, and the anti-aging effect can not be well achieved only by promoting epidermal growth and supplementing the collagen externally to realize anti-aging.

Disclosure of Invention

The first purpose of the invention is to provide a muscle bottom essence which achieves the effects of repairing skin and stabilizing skin barrier so as to achieve the anti-aging effect.

The second purpose of the invention is to provide a preparation method of the essence for the muscle bottom, which achieves the effect of obtaining more uniform essence.

In order to achieve the first object, the invention provides the following technical scheme:

the muscle bottom essence is prepared from the following raw materials in percentage by weight:

group A:

261-4% of glyceryl polyether;

1-4% of 1, 3-propylene glycol;

1-4% of humectant A: consists of 60 to 65 weight percent of glycerin, 1 to 4 weight percent of glycerin acrylate/acrylic acid copolymer and the balance of water;

1-4% of humectant B: consists of 99.5 percent of glycerin by weight percentage and the balance of water;

1-4% of humectant C: consists of 0.05 to 1 weight percent of ethylhexyl glycerol, 3 to 5 weight percent of 1, 2-pentanediol, 0.2 to 0.5 weight percent of sodium hyaluronate cross-linked polymer, 0.5 to 1 weight percent of sodium hyaluronate, 0.5 to 1.2 weight percent of sodium acetylated hyaluronate, 0.1 to 0.2 weight percent of hydrolyzed hyaluronic acid and the balance of water;

1-4% of solvent A: consists of 5 percent of stearyloxy PG-hydroxyethyl cellulose sodium sulfonate, 1 percent of 1, 2-hexanediol, 30 percent of butanediol and the balance of water;

1-4% of thickening agent: consists of 8 to 12 weight percent of sodium polyacryl dimethyl taurate, 6 weight percent of hydrogenated polydecene, 1 to 3 weight percent of tridecyl polyether-10 and the balance of water;

0.4-2% of 1, 2-hexanediol;

0.4 to 1 percent of p-hydroxyacetophenone;

0.05 to 0.5 percent of acryloyl dimethyl ammonium taurate/VP copolymer;

0.03-0.5% of xanthan gum;

0.05 to 0.15 percent of EDTA disodium;

group B:

1-6% of butanediol;

carbomer 0.05-0.4%;

group C:

0.05-0.4% of tromethamine;

group D:

5-15% of conditioning agent X: 97-98% of a lysate of a fermentation product of a yeast for secondary cracking, 0.9-1.1% of phenoxyethanol, 0.2-0.3% of sodium benzoate, 0.14-0.18% of acetic acid and the balance of lactic acid;

1-4% of a conditioner A;

0.01 to 0.5 percent of conditioner B;

0.01-1% of conditioner C;

0.1-3% of conditioner D: consists of 30 percent of butanediol by weight percentage, 1.2 percent of plankton extract by weight percentage and the balance of water;

0.1-5% of a conditioning agent E;

0.1 to 3 percent of conditioner F;

0.1-3% of conditioner G: comprises 20-40 wt% of myrtle leaf extract, 0.5 wt% of phenoxyethanol, 0.2 wt% of ethylhexyl glycerol, and the balance of water;

0.05 to 0.5 percent of ethylhexyl glycerol;

the balance of water.

By adopting the technical scheme, the group A mainly comprises a solvent, a humectant, a thickening agent and other auxiliary agents.

The glyceryl polyether-26 is a glycerin polymer of 26 EO, is used as a humectant, is applied to skin care products, is stable in property, is very good in compatibility with all components, and can improve the sticky and skin feeling of the essence when the essence is half-dry, improve the use feeling of the product and improve the freshness.

The solvent mainly comprises 1, 3-propylene glycol and 1, 2-hexanediol. The 1, 3-propylene glycol can be mixed with water and ethanol, has hygroscopicity and viscosity, is mild to skin, is natural and non-petroleum based diol, can be used as a humectant, a thickener and a solvent at the same time, and can reduce the overall sticky feeling of the essence by being matched with the glyceryl polyether-26. The 1, 2-hexanediol is used as a solvent, a humectant and a penetration aid, and is also used as a preservative which is contacted with a human body. The p-hydroxyacetophenone is a natural plant extract, is a mild, additive-free and non-irritant preservative, has the functions of resisting oxidation, tranquilizing and relieving, and has a synergistic effect after being compounded with the 1, 2-hexanediol.

The acryloyl dimethyl ammonium taurate/VP copolymer has excellent emulsifying, dispersing and thickening capabilities, and is used for improving the dispersibility and emulsibility of each component in the essence and adjusting the overall viscosity of the essence. The xanthan gum is a microbial extracellular polysaccharide with wide effect, has unique rheological property, good water solubility, stability to heat and acid and alkali and good compatibility with various salts, is used as a thickening agent, a suspending agent, an emulsifying agent and a stabilizing agent, and can form a super-bonding banded spiral copolymer to form a fragile gel-like net structure, so that the xanthan gum can support the forms of solid particles, liquid drops and bubbles, shows strong emulsification stability and high suspension capacity and enhances the emulsification effect of raw materials. Disodium EDTA as a chelating agent, which is complexed with metal ions, softens hard water, reduces the oxidation of technical ions to the whole formula, and protects and stabilizes the whole formula.

The humectant A and the humectant B mainly comprise the most basic glycerin and water to form the humectant, and the glycerin acrylate/acrylic acid copolymer is used as a thickening agent to adjust the overall fluidity of the humectant A so as to enable the humectant A to meet the viscosity requirement of a product. The humectant C contains 4 types of hyaluronic acid, a three-dimensional sponge layer structure is constructed, high-efficiency water storage and water locking are realized, the hyaluronic acid with different characteristics can accurately position the surface, the cuticle layer, the epidermal layer and the dermis layer of the skin, the three-dimensional moisturizing effect is exerted instantly, the outer layer replenishes water, the inner layer locks water, the skin is nursed in an all-around and all-layer manner, and the water replenishing and moisturizing are realized. The solvent a and the thickener mainly achieve dissolution of the respective components to adjust the viscosity of the group a as a whole.

The B group is a solvent group mainly containing a butanediol solvent, and the poloxamer is mainly used for adjusting the viscosity of the essence so as to adjust the properties of the essence product. Tromethamine in group C is used as a pH regulator, so that the pH value of the essence is in a certain range, and the essence in the range is stable in property and is not easy to deteriorate and oxidize.

Group D is an important combination of active ingredients in the formulation. The lysate of the yeast fermentation product of the second split yeast contained in the conditioner X has strong anti-immunosuppression activity and can promote DNA repair and effectively protect the skin; on the other hand, the myrtle leaf extract contained in the conditioner G can promote the synthesis of SIRT-1 cell longevity protein, can also regulate and recombine intercellular communication protein-CAVEOLIN-1, locks irreversible collagen saccharification reaction and stabilizes cells, improves self-defense and repair mechanisms, and forms a skin barrier. The plankton extract of the conditioner D contains GP4G nucleotide, GP4G nucleotide can provide unique energy for skin, so that the restoration is realized by matching with the lysate of the fermentation product of the schizosaccharomyces cerevisiae, and meanwhile, energy is supplied for cell recombination and the synthesis of longevity protein, and the restoration effects of the conditioner X and the conditioner D are greatly improved.

Ultraviolet rays are a large reason for skin aging, the skin barrier can be damaged by the ultraviolet rays, skin cells are damaged, the lysate of the yeast fermentation product of the bifida can stimulate and assist the skin to repair the DNA of the skin, the DNA damage is avoided, the skin is effectively protected, and the repair and the relief are realized; the joss wood leaf extract is matched to promote the synthesis of longevity protein, hinder the saccharification reaction, realize the stability of cells, and simultaneously the plankton extract provides recombination, repair and stable energy for the skin; on the whole, the skin cells can be activated and rejuvenated from both the aspects of repair and stabilization to strengthen the skin barrier and thus achieve anti-aging, thereby obtaining a continuously superior anti-aging effect.

In addition, the plankton extract can help the skin to resist and absorb ultraviolet radiation and infrared radiation which cause premature senility, and the overheated or supercooled environment temperature and pressure which cause premature senility, help mitochondria to resist ultraviolet radiation and infrared radiation, and protect the energy mechanism of cells; and the repaired cells are reversely protected and participate in the process of stabilizing the cells by the myrtle leaf extract, and the cell stabilizing effect is improved, so that the cells are activated, the cells are kept young, the skin barrier is strengthened, and the anti-aging effect is further improved.

More preferably: the conditioner F consists of 79.4% by weight of glycerol, 20% by weight of edelweiss callus extract, 0.3% by weight of citric acid and 0.3% by weight of xanthan gum.

By adopting the technical scheme, the active substance in the conditioner F is the alpine edelweiss callus extract, so that a remarkable lifting effect can be brought to the skin, and the effects of smoothing wrinkles and firming the skin are achieved; meanwhile, the specific high-antioxidation characteristic of the collagen can repair and maintain the activity of mitochondria and improve the contractility of mitochondria, and can promote the synthesis of collagen, so that the skin can obtain enough collagen, the skin cells can become plump, and the skin becomes full of water, fine and smooth and can effectively resist aging. The conditioner F is matched with the plankton extract of the conditioner D for use, so that the mitochondria are comprehensively protected and activated, the function of extending the mitochondria as a cell energy mechanism is maintained and even prolonged, and the mitochondria provide energy for the cells, so that the stability of the cells is indirectly realized, the formation of a skin barrier is facilitated, the occurrence of damage is reduced, and the anti-aging is realized.

More preferably: the conditioner A consists of 95.01-99 wt% of 1, 3-propylene glycol and the balance of ulmus pumila bark extract.

By adopting the technical scheme, the active substances in the slippery fruit elm bark extract are divided into two polyphenols, namely ellagic acid and 3, 3' -O-dimethyl ellagic acid, which are effective antioxidants, can inhibit the formation of active oxygen free radicals on the skin epidermis layer, inhibit the activities of MMP-2 and MMP-9 enzymes, slow down the degradation of IV collagen, and increase the absorption and utilization of Vc by fibroblasts in the whole cortex layer to promote whitening and the synthesis of collagen. Conditioning agent A achieves anti-aging of the skin through three synergistic effects. On the other hand, the conditioning agent D can provide energy for fibroblasts, and further enhance the absorption and utilization of Vc.

More preferably: the conditioner E comprises 98.5 wt% of lactobacillus fermentation lysate, 0.8 wt% of lactic acid, 0.35 wt% of sodium chloride and 0.35 wt% of sodium benzoate.

By adopting the technical scheme, the epidermis is the outermost layer of the skin and is used as a physical barrier, the human body can be separated from the harmful external environment, the renewal speed of the epidermis is about 3-5 weeks, and the lactobacillus fermentation lysate has positive effects on the growth speed and the quality of the epidermis. In addition, it is effective in promoting the exfoliation of dead cells, promoting the synthesis of essential proteins and enzymes affecting skin quality, and improving barrier function and cell binding force.

More preferably: the conditioner C comprises 30 wt% of glycerol, 1.4-1.6 wt% of phenoxyethanol, 1.0-1.5 wt% of Adansonia dubia seed extract and the balance of water.

By adopting the technical scheme, the macaque bread tree has the genetic information of adaptation, resistance, strength and longevity in order to develop the rapid adaptability of plants in response to environmental pressure, and simultaneously can store a great amount of water to be lower than dry welding, and the macaque bread tree seed extract is rich in plant small molecular RNA, so that the apparent wrinkles of the skin can be reduced, and the moisturizing performance of the skin can be improved.

More preferably: the conditioner B consists of 99.90 percent of madecassoside by weight and the balance of water.

By adopting the technical scheme, the madecassoside is an active ingredient with a relieving effect, and can effectively resist all influences of inflammation, so that the pressure caused by sensitive skin is relieved, and the essence has the effects of stabilizing and comforting the sensitive skin.

More preferably: the emollient is hypsizygus marmoreus callus culture filtrate.

By adopting the technical scheme, the hypecoum anisopliae callus culture filtrate contains the plant stem cells which are undifferentiated natural cells, can control primary metabolism, meet the basic functional requirements of cell growth, development and reproduction, and simultaneously can control stimulated metabolism to adapt to the external pressure on the skin, thereby realizing dermis restoration, reconstruction and skin barrier restoration, and realizing anti-aging and protection. Meanwhile, melanin can be reduced, and the brightening effect is realized.

In order to achieve the second object, the invention provides the following technical scheme:

a preparation method of a muscle bottom essence comprises the following steps:

s1: adding water into the raw materials of the group B, and uniformly mixing to prepare a 2% water dispersion of the group B;

s2: adding water into the raw material of group C, and mixing to obtain 10% aqueous dispersion of group C

S3: uniformly mixing all the raw materials of the group A and the rest water, gradually heating to 76-80 ℃ while stirring, and preserving heat to obtain a group A mixed solution;

s4: adding the aqueous dispersion of the group B into the mixed solution of the group A, and uniformly mixing;

s5: reducing the temperature of the mixed solution obtained in the step S4 to 65-70 ℃, adding the C group water dispersion, uniformly mixing, and continuously reducing the temperature;

s6: reducing the temperature of the mixed solution obtained in the step S5 to 45 ℃ or below, adding all the raw materials in the group D, and fully mixing;

s7: cooling to 37 deg.C or below, sampling to determine whether specific gravity is 1.000-1.040g/cm2, pH is 5.50-6.80, and viscosity reaches standard as follows: 30rpm, 20 ℃, 1500-;

s1, S2 and S3 may be performed simultaneously.

By adopting the technical scheme, the group A, the group B and the group C are respectively pretreated, the components are fully dispersed, then the group A and the group B are uniformly mixed, and then the group A and the group B are uniformly mixed with the group C, and then the active component of the group D is added under the low temperature condition, so that the preparation of the essence is realized. The essence obtained by pretreatment is more uniform, and generally does not have transparent or semitransparent particles, so that the stability of the physical properties of the essence is ensured, and a very good experience feeling is provided for customers; on the other hand, the active ingredients are added after the temperature is reduced, so that the problem of efficiency reduction caused by the fact that the active ingredients are added when the temperature is too high can be solved.

More preferably: in step S1, all the raw materials of group B are mixed uniformly, and then water is added and mixed to prepare a 2% group B aqueous dispersion.

By adopting the technical scheme, the raw material B is dispersed first, and then the water dispersion is prepared, so that the uniformity of the B group water dispersion is improved.

More preferably: in the step S4, after the group B water dispersion is added into the group A mixed solution, the mixture is firstly homogenized for 2.5-5min and then stirred and mixed for 8-15 min; in step S5, after the group C aqueous dispersion is added, the mixture is homogenized for 2.5-5min, and then stirred and mixed for 5-8 min.

Adopt above-mentioned technical scheme, need high-speed stirring during the homogeneity, the effect that can improve mixture and emulsification is stirred again to earlier the homogeneity of improvement essence.

In conclusion, the invention has the following beneficial effects:

1. by adopting the conditioner D, the conditioner X and the conditioner G, the anti-aging effect is achieved from the two aspects of repair and stabilization, so that a continuous excellent anti-aging effect is obtained, meanwhile, an energy mechanism of cells can be protected, the repaired cells are reversely protected, the process of stabilizing the cells by the myrtle leaf extract is participated, the effect of stabilizing the cells is improved, a stable skin barrier is formed and brought, the skin barrier is gradually strengthened in the using process, the external stimulation is reduced, and the anti-aging effect is achieved.

2. By adopting the cooperation of the conditioner F and the conditioner D, the comprehensive protection and activation of mitochondria are realized, the function of mitochondria as a cell energy mechanism is maintained and even prolonged, the energy provided by mitochondria to cells is well guaranteed, and the cells are activated and rejuvenated, so that a skin barrier is formed, and the stabilization and the anti-aging of the skin are indirectly realized.

3. By adopting the preparation method of pre-treating and mixing, the obtained essence is more uniform, transparent or semitransparent granules can not appear generally, the stability of the physical properties of the essence is ensured, and a very good experience is provided for customers.

4. By adding the active ingredients after cooling, the problem of reduced efficacy caused by the fact that the active ingredients are added when the temperature is too high can be avoided.

Detailed Description

Examples 1 to 10: a muscle bottom essence, examples 1-5 comprising the components and corresponding masses shown in Table 1 (calculated on the basis of 500kg in total), was prepared by the following steps:

s1: adding the raw materials of group B into a first reaction kettle, fully mixing for 5min at a stirring speed of 800r/min, adding part of water, fully mixing for 8min at a stirring speed of 1000r/min, and preparing into 2% aqueous dispersion of group B;

s2: adding group C raw materials into a second reaction kettle, fully mixing for 5min at a stirring speed of 500r/min, adding part of water, and fully mixing for 8min at a stirring speed of 1200r/min to prepare 10% group C aqueous dispersion;

s3: adding the group A raw materials and the rest water into a third reaction kettle, stirring for 8min at a stirring speed of 1500r/min, gradually heating to 76 ℃ while stirring, and preserving heat to obtain a group A mixed solution;

s4: adding the group B aqueous dispersion into the group A mixed solution, stirring at a stirring speed of 3500r/min for 3min, and then stirring at a stirring speed of 1500r/min for 8 min;

s5: reducing the temperature of the mixed solution obtained in the step S4 to 65 ℃, adding the group C aqueous dispersion, stirring at a stirring speed of 3500r/min for 3min, and then stirring at a stirring speed of 1500r/min for 5 min;

s6: reducing the temperature of the mixed solution obtained in the step S5 to 45 ℃ or below, adding all the raw materials in the group D, stirring for 7min at a stirring speed of 2000r/min, and continuously reducing the temperature;

s7: cooling to 37 ℃ and below, sampling to detect whether the specific gravity is between 1.000 and 1.040g/cm2, whether the pH is between 5.50 and 6.80, and discharging when the viscosity standard is 30rpm and 20 ℃, and 1500 plus 2500pa s are qualified.

TABLE 1 examples 1-5 compositions and corresponding masses (kg)

In the above embodiment, the humectant B is composed of 99.5% by weight of glycerin and the balance of water; the conditioner D consists of 30 percent by weight of butanediol, 1.2 percent by weight of plankton extract and the balance of water; the solvent A consists of 30 percent by weight of butanediol, 5 percent by weight of sodium stearyl-oxy PG-hydroxyethyl cellulose sulfonate, 1 percent by weight of 1, 2-hexanediol and the balance of water. The emollient is hypecoum vulgaris callus culture filtrate.

In example 1, conditioner X consists of 97% by weight of a schizosaccharomyces fermentate lysate, 1.1% by weight of phenoxyethanol, 0.3% by weight of sodium benzoate, 0.14% by weight of acetic acid, and the balance lactic acid.

The conditioner A comprises 80 wt% of 1, 3-propanediol and the balance of an extract of Ulmus pumila bark. Conditioning agent B comprises 50 wt% of madecassoside and the balance of water. Conditioning agent C comprises 20 wt% of glycerol, 1.4 wt% of phenoxyethanol, 1.0 wt% of Paeonia Macaca seed extract, and balance of water.

Conditioner E consisted of 98.5% by weight of a lactic acid bacteria fermentation lysate, 0.8% by weight of lactic acid, 0.35% by weight of sodium chloride and 0.35% by weight of sodium benzoate. Conditioning agent F comprises 60 wt% of glycerol, 0.3 wt% of citric acid, 0.3 wt% of xanthan gum, and the balance of Leontopodium alpinum callus extract.

Conditioning agent G comprises 20 wt% of myrtle leaf extract, 0.5 wt% of phenoxyethanol, 0.2 wt% of ethylhexyl glycerin, and the balance of water.

The humectant A consists of 60 wt% of glycerin, 1 wt% of glycerin acrylate/acrylic acid copolymer and the balance of water. The humectant C consists of 0.05 weight percent of ethylhexyl glycerin, 3 weight percent of 1, 2-pentanediol, 0.2 weight percent of sodium hyaluronate cross-linked polymer, 0.5 weight percent of sodium hyaluronate, 0.5 weight percent of sodium acetylated hyaluronate, 0.1 weight percent of hydrolyzed hyaluronic acid and the balance of water.

The thickening agent consists of 8 percent by weight of sodium polyacryl dimethyl taurate, 6 percent by weight of hydrogenated polydecene, 1 percent by weight of tridecyl polyether-10 and the balance of water.

In example 2, conditioner X consisted of 98% by weight of a split yeast fermentation lysate, 1% by weight of phenoxyethanol, 0.22% by weight of sodium benzoate, 0.16% by weight of acetic acid, and the balance lactic acid.

The conditioner A comprises 80 wt% of 1, 3-propanediol and the balance of an extract of Ulmus pumila bark. The conditioner B consists of 80 percent of madecassoside by weight and the balance of water. Conditioning agent C comprises 30 wt% of glycerol, 1.4 wt% of phenoxyethanol, 1.0 wt% of Paeonia Macaca seed extract, and balance of water.

Conditioner E consisted of 98.5% by weight of a lactic acid bacteria fermentation lysate, 0.8% by weight of lactic acid, 0.35% by weight of sodium chloride and 0.35% by weight of sodium benzoate. Conditioning agent F comprises 85 wt% of glycerol, 0.3 wt% of citric acid, 0.3 wt% of xanthan gum, and the balance of Leontopodium alpinum callus extract.

Conditioning agent G comprises 35 wt% of myrtle leaf extract, 0.5 wt% of phenoxyethanol, 0.2 wt% of ethylhexyl glycerin, and the balance of water.

The humectant A was composed of 62% by weight of glycerin, 3% by weight of a glycerin acrylate/acrylic acid copolymer, and the balance water. The humectant C consists of 0.5 weight percent of ethylhexyl glycerin, 4 weight percent of 1, 2-pentanediol, 0.3 weight percent of sodium hyaluronate crosspolymer, 0.8 weight percent of sodium hyaluronate, 0.85 weight percent of sodium acetylated hyaluronate, 0.12 weight percent of hydrolyzed hyaluronic acid and the balance of water.

The thickening agent consists of 9 weight percent of sodium polyacryl dimethyl taurate, 6 weight percent of hydrogenated polydecene, 2 weight percent of tridecyl polyether-10 and the balance of water.

In example 3, conditioner X consisted of 97% by weight of a split yeast fermentation lysate, 0.9% by weight of phenoxyethanol, 0.2% by weight of sodium benzoate, 0.18% by weight of acetic acid, and the balance lactic acid.

Conditioner A comprises 95.01 wt% 1, 3-propanediol and the balance of Ulmus pumila bark extract. Conditioning agent B comprises 50 wt% of madecassoside and the balance of water. Conditioning agent C comprises 30 wt% of glycerol, 1.6 wt% of phenoxyethanol, 1.5 wt% of Paeonia Macaca seed extract, and balance of water.

Conditioner E consisted of 98.5% by weight of a lactic acid bacteria fermentation lysate, 0.8% by weight of lactic acid, 0.35% by weight of sodium chloride and 0.35% by weight of sodium benzoate. Conditioner F consisted of 79.4% by weight glycerol, 0.3% by weight citric acid, 0.3% by weight xanthan gum and the balance alpine edelweiss callus extract.

Conditioning agent G comprises (by weight) myrtle leaf extract 40%, phenoxyethanol 0.5%, ethylhexyl glycerin 0.2%, and water in balance.

The humectant A was composed of 65% by weight of glycerin, 4% by weight of a glycerin acrylate/acrylic acid copolymer, and the balance water. The humectant C consists of 1% by weight of ethylhexyl glycerin, 5% by weight of 1, 2-pentanediol, 0.5% by weight of sodium hyaluronate cross-linked polymer, 1% by weight of sodium hyaluronate, 1.2% by weight of sodium hyaluronate, 0.2% by weight of hydrolyzed hyaluronic acid, and the balance of water.

The thickening agent consists of 12 weight percent of sodium polyacryl dimethyl taurate, 5 weight percent of hydrogenated polydecene, 3 weight percent of tridecyl polyether-10 and the balance of water.

In example 4, conditioner X consisted of 97% by weight of a schizosaccharomyces fermentate lysate, 0.9% by weight of phenoxyethanol, 0.3% by weight of sodium benzoate, 0.18% by weight of acetic acid, and the balance lactic acid.

The conditioner A comprises 97 wt% 1, 3-propanediol and the balance of an extract of Ulmus pumila bark. Conditioning agent B comprises 99.9 wt% of madecassoside and the balance of water. Conditioning agent C comprises 30 wt% of glycerol, 1.5 wt% of phenoxyethanol, 1.2 wt% of Adansonia dubia seed extract, and the balance of water.

Conditioner E consisted of 98.5% by weight of a lactic acid bacteria fermentation lysate, 0.8% by weight of lactic acid, 0.35% by weight of sodium chloride and 0.35% by weight of sodium benzoate. Conditioner F consisted of 79.4% by weight of glycerol, 0.3% by weight of citric acid, 0.3% by weight of xanthan gum and the balance of leontopodium odoratum callus extract.

Conditioning agent G comprises 38 wt% of myrtle leaf extract, 0.5 wt% of phenoxyethanol, 0.2 wt% of ethylhexyl glycerin, and balance water.

The humectant A consisted of 51% by weight of glycerin, 2.5% by weight of a glycerin acrylate/acrylic acid copolymer and the balance water. The humectant C consists of 0.8 wt% of ethylhexyl glycerin, 5 wt% of 1, 2-pentanediol, 0.33 wt% of sodium hyaluronate crosspolymer, 0.88 wt% of sodium hyaluronate, 0.85 wt% of sodium acetylated hyaluronate, 0.2 wt% of hydrolyzed hyaluronic acid, and the balance of water.

The thickener consists of 8.5 wt% of sodium polyacryl dimethyl taurate, 6 wt% of hydrogenated polydecene, 2.2 wt% of tridecyl polyether-10 and the balance of water.

In example 5, conditioner X consisted of 97% by weight of a split yeast fermentation lysate, 0.9% by weight of phenoxyethanol, 0.3% by weight of sodium benzoate, 0.18% by weight of acetic acid, and the balance lactic acid.

The conditioner A comprises 80 wt% of 1, 3-propanediol and the balance of an extract of Ulmus pumila bark. The conditioner B consists of 50 percent of madecassoside by weight and the balance of water. Conditioning agent C comprises 10 wt% of glycerol, 0.5 wt% of phenoxyethanol, 3 wt% of Adansonia dubia seed extract, and balance of water.

Conditioner E by weight percentage of 99% lactic acid bacteria fermentation lysate, weight percentage of 0.02% lactic acid, weight percentage of 0.02% sodium chloride and the balance of sodium benzoate composition. Conditioner F consisted of 79.4% by weight of glycerol, 0.3% by weight of citric acid, 0.3% by weight of xanthan gum and the balance of leontopodium odoratum callus extract.

Conditioner G consists of 38% by weight of myrtle leaf extract, 0.5% by weight of phenoxyethanol, 0.2% by weight of ethylhexyl glycerin, and the balance water.

Humectant A consisted of 51% by weight glycerin, 2.5% by weight glycerin acrylate/acrylic acid copolymer, and the balance water. The humectant C was composed of 0.8% by weight of ethylhexyl glycerin, 5% by weight of 1, 2-pentanediol, 0.33% by weight of sodium hyaluronate crosspolymer, 0.88% by weight of sodium hyaluronate, 0.85% by weight of sodium hyaluronate acetylated, 0.2% by weight of hydrolyzed hyaluronic acid, and the balance of water.

Example 6: the difference from example 5 is that conditioner a in this example consists of 99% by weight of 1, 3-propanediol and the balance of ulmus pumila bark extract.

Example 7: the difference from example 6 is that conditioner E in this example consists of 98.5% by weight of a lactic acid bacteria fermentation lysate, 0.8% by weight of lactic acid, 0.35% by weight of sodium chloride and the balance sodium benzoate.

Example 8: the difference from example 7 is that conditioner C in this example consists of 30% by weight glycerol, 1.4% by weight phenoxyethanol, 1.0% by weight of the extract of the seeds of the bushy angle and the balance water.

Example 9: the difference from example 8 is that conditioner B consists of 99.9% by weight of madecassoside, the remainder being water.

Example 10: the difference from example 1 is that in this example, conditioner a was tridecyl alcohol salicylate, conditioner B was trehalose, conditioner C was aloe vera extract, conditioner E was synthetic vitamin E oil, and conditioner F was snail slime extract.

Example 11: a preparation method of a muscle bottom essence comprises the following steps:

s1: adding the raw materials of group B into a first reaction kettle, fully mixing for 5min at a stirring speed of 500r/min, adding part of water, fully mixing for 8min at a stirring speed of 1000r/min, and preparing into 2% aqueous dispersion of group B;

s2: adding group C raw materials into a second reaction kettle, fully mixing for 5min at a stirring speed of 800r/min, adding part of water, and fully mixing for 7min at a stirring speed of 1200r/min to prepare 10% group C aqueous dispersion;

s3: adding the group A raw materials and the rest water into a third reaction kettle, stirring for 8min at a stirring speed of 1500r/min, gradually heating to 80 ℃ while stirring, and preserving heat to obtain a group A mixed solution;

s4: adding the water dispersion of group B into the mixed solution of group A, stirring at 3500r/min for 3min, and then at 1500r/min for 15 min;

s5: reducing the temperature of the mixed solution obtained in the step S4 to 65 ℃, adding the group C aqueous dispersion, stirring at a stirring speed of 3500r/min for 3min, and then stirring at a stirring speed of 1500r/min for 8 min;

s6: reducing the temperature of the mixed solution obtained in the step S5 to 45 ℃ or below, adding all the raw materials in the group D, stirring for 7min at the stirring speed of 2000r/min, and continuously cooling;

Example 11: a method for preparing a foundation essence, which is different from example 10 in that S1: adding the raw materials of the group B and part of water into a first reaction kettle, and fully mixing for 8min at a stirring speed of 1000r/min to prepare a 2% aqueous dispersion of the group B.

Example 12: a method for preparing a foundation essence, which is different from example 10 in that S4: adding the B group water dispersion into the A group mixed solution, and stirring at a stirring speed of 1500r/min for 18 min; s5: and (4) reducing the temperature of the mixed solution obtained in the step (S4) to 65 ℃, adding the group C aqueous dispersion, and stirring at the stirring speed of 1500r/min for 11 min.

Comparative examples 1 to 5: a muscle foundation essence, which is different from example 10 in that it comprises the following components and corresponding masses as shown in table 2:

TABLE 2 comparative examples 1-5 compositions and corresponding masses (kg)

Characterization experiment:

1. evaluation of human skin test

Subject: examples 1-10 and comparative examples 1-5, for a total of 15 experimental groups.

The experimental method comprises the following steps: 45 women between 20-30 years old are found and divided into 1-15 groups of women, and the test is carried out corresponding to 15 groups of experimental samples. A 10D use experience was performed and observations were tracked daily, with test items comprising: 1. percutaneous water loss, and the testing instrument is a VapoMeter; 2. skin stratum corneum is hydrated, the tester is MoistureMeter SC-skin stratum corneum hydration measuring instrument; 3. skin brightness, the testing instrument is a skin brightness measuring instrument of SkinGlossMeter; 4. sebum, sebumeter, sebumscacle-sebum meter. The data before use needs to be obtained 1 day before use, D1, D2, D3, D6, D7, D8, D9 and D10 in the use period need timing tests, and the test time is 16: 00-17: 00, data are the average of five women in each group.

The experimental results are as follows: the results of the evaluation of the skin test of the population are shown in tables 3 to 5, and the results before and after use are shown in table 6.

TABLE 3 record of skin test evaluation results for D1-D2 population before use

TABLE 4 records of the results of skin test evaluation of the population D3, D6-D7

TABLE 5 records of evaluation results of skin tests of D8-D10 population

TABLE 6 record of results of comparative experimental evaluation of effects before and after use

And (3) data analysis: the percutaneous water loss, the hydration of the stratum corneum and the sebum of the skin can reflect the barrier function of the skin and the health and youth states of the skin, so that the effects of the essence on repairing the skin barrier and resisting aging are reflected, the data of the embodiment is superior to the data of the comparative example, and the embodiment can better realize the repair, the anti-aging and the stabilization of the skin barrier.

The percutaneous water loss can reflect the water loss condition, so that the water retention capacity of cell skin and the skin youth degree are judged, and the normal value is below 15. The embodiment reduces the percutaneous water loss before and after the use, and regulates the skin, so that the moisturizing capability of a testee is maintained within a normal value; the relatively poor results of example 10 compared to the remaining examples are the difference between conditioners A, B, C, E and F. The conditioner X, the conditioner D and the conditioner G adopted in the comparative example are not in the range or are not directly adopted, so that the mutual synergistic effect is not achieved, the change is not obvious, and the adjustment of the percutaneous water loss cannot be well embodied. The embodiment can well activate and repair cells and improve the water retention performance of the cells, so that the skin is kept in a young state, and the anti-aging and repair effects are realized.

The stratum corneum hydration of the skin has a normal value of 20-50, and frequent skin hydration can damage the protective barrier of the skin and cause skin damage. In the embodiment, after 10 days of use, the hydration of the stratum corneum of the skin in an abnormal range is gradually changed into a normal value and is partially and gradually close to the normal value in a tested person; the testee originally in the normal range is still in the normal range. The conditioning agents X, D and G used in the comparative examples were not within the range or were not used directly, so they did not act synergistically and were effective but not significant in regulating the hydration of the stratum corneum. The embodiment can well activate and repair cells, reshape and stabilize skin barriers, keep skin in a young state and realize anti-aging and repair.

The skin sebum refers to the thickness of the sebum, and in the embodiment, after the essence is used, the sebum of a person who is too thin can be thickened properly to form a skin barrier, so that the skin can be protected better; and moreover, the sebum of a person with excessively thick sebum can be properly thinned, the air permeability of the skin is increased, and the oiliness of the skin is relieved. The conditioner X, the conditioner D and the conditioner G adopted in the comparative example are not in the range or are not adopted directly, so that the mutual synergistic effect is not achieved, and the regulation effect on sebum is not obvious. The illustrative embodiments provide for a superior remodeling and stabilization of the skin barrier, thereby maintaining youthful appearance of the skin and achieving anti-aging and healing.

The above-mentioned embodiments are merely illustrative and not restrictive, and those skilled in the art can modify the embodiments without inventive contribution as required after reading this specification, but only fall within the scope of the claims of the present invention.

Claims

1. The muscle bottom essence is characterized by being prepared from the following raw materials in percentage by weight:

group A:

261-4% of glyceryl polyether;

1-4% of 1, 3-propylene glycol;

1-4% of humectant C: consists of 0.05 to 1 weight percent of ethylhexyl glycerol, 3 to 5 weight percent of 1, 2-pentanediol, 0.2 to 0.5 weight percent of sodium hyaluronate cross-linked polymer, 0.5 to 1 weight percent of sodium hyaluronate, 0.5 to 1.2 weight percent of acetylated sodium hyaluronate, 0.1 to 0.2 weight percent of hydrolyzed hyaluronic acid and the balance of water;

1-4% of thickening agent: consists of 8.5 percent of sodium polyacryl dimethyl taurate, 6 percent of hydrogenated polydecene, 2.2 percent of tridecyl polyether-10 and the balance of water;

0.4-2% of 1, 2-hexanediol;

0.4-1% of p-hydroxyacetophenone;

0.05 to 0.5 percent of acryloyl dimethyl ammonium taurate/VP copolymer;

0.03-0.5% of xanthan gum;

0.05 to 0.15 percent of EDTA disodium;

group B:

1-6% of butanediol;

carbomer 0.05-0.4%;

group C:

0.05 to 0.4 percent of tromethamine;

group D:

5-15% of conditioning agent X: consists of 97 percent by weight of a schizosaccharomyces cerevisiae fermentation product lysate, 0.9 percent by weight of phenoxyethanol, 0.3 percent by weight of sodium benzoate, 0.18 percent by weight of acetic acid and the balance of lactic acid;

1-4% of a conditioner A;

0.01-0.5% of conditioner B: consists of 99.90 percent of madecassoside and the balance of water by weight percentage;

0.01 to 1 percent of conditioner C;

0.1-5% of a conditioning agent E;

0.1 to 3 percent of conditioner F;

0.1-3% of conditioner G: consists of 38 percent of myrtle leaf extract, 0.5 percent of phenoxyethanol, 0.2 percent of ethylhexyl glycerol and the balance of water;

0.05 to 0.5 percent of ethylhexyl glycerol;

tetrahydro-methyl-pyrimidine-carboxylic acid, appropriate amount;

emollient, right amount;

the balance of water;

the preparation method of the muscle bottom essence comprises the following steps:

s4: adding the water dispersion solution of the group B into the mixed solution of the group A, and uniformly mixing;

s7: cooling to 37 deg.C or below, sampling to determine whether specific gravity is 1.000-1.040g/cm²Whether the pH value is between 5.50 and 6.80 and the viscosity reaches the standard, wherein the viscosity standard is as follows: 30rpm, 20 ℃, 1500-;

s1, S2 and S3 may be performed simultaneously.

2. The essence of claim 1, wherein the conditioner F comprises 79.4 wt% of glycerin, 20 wt% of the extract of the callus of Leontopodium alpinum, 0.3 wt% of citric acid, and 0.3 wt% of xanthan gum.

3. The essence for muscle base of claim 1 or 2, wherein conditioner a comprises 95.01-99 wt% of 1, 3-propanediol and the balance of ulmus pumila bark extract.

4. The essence of muscle base of claim 3, wherein conditioner E comprises 98.5% by weight of lactic acid bacteria fermentation lysate, 0.8% by weight of lactic acid, 0.35% by weight of sodium chloride, and 0.35% by weight of sodium benzoate.

5. The essence for muscle base of claim 4, wherein conditioner C comprises 30 wt% of glycerin, 1.4-1.6 wt% of phenoxyethanol, 1.0-1.5 wt% of Paeonia championii seed extract, and the balance of water.

6. The essence of muscle base according to claim 1, wherein the emollient is hypsizygus marmoreus callus culture filtrate.

7. The essence for muscle base of claim 1, wherein in step S1, all the raw materials of group B are mixed uniformly, and then mixed with water to form a 2% aqueous dispersion of group B.

8. The essence for muscle base of claim 7, wherein in step S4, the aqueous dispersion of group B is added to the mixed solution of group a, followed by homogenizing for 2.5-5min, and then stirring and mixing for 8-15 min; in step S5, after the group C aqueous dispersion is added, the mixture is homogenized for 2.5-5min, and then stirred and mixed for 5-8 min.