CN110691512A - 遗传工程化的非人类哺乳动物及其构建方法和应用 - Google Patents
遗传工程化的非人类哺乳动物及其构建方法和应用 Download PDFInfo
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Abstract
一种遗传工程化的非人哺乳动物、细胞、器官和组织及其产生方法，以及所述非人哺乳动物、细胞、器官和组织在筛选或验证治疗药物中的应用。
Description
PCT国内申请，说明书已公开。
Claims (50)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710292460X | 2017-04-28 | ||
| CN201710292460 | 2017-04-28 | ||
| PCT/CN2018/085097 WO2018196874A1 (zh) | 2017-04-28 | 2018-04-28 | 遗传工程化的非人类哺乳动物及其构建方法和应用 |
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| Publication Number | Publication Date |
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| CN110691512A true CN110691512A (zh) | 2020-01-14 |
| CN110691512B CN110691512B (zh) | 2021-11-09 |
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| CN201880028071.9A Active CN110691512B (zh) | 2017-04-28 | 2018-04-28 | 遗传工程化的非人类哺乳动物及其构建方法和应用 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US11882816B2 (zh) |
| CN (1) | CN110691512B (zh) |
| WO (1) | WO2018196874A1 (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110205375A (zh) * | 2019-06-26 | 2019-09-06 | 宁夏医科大学 | 一种动脉粥样硬化诊断用分子标志物及其应用 |
| CN114304064A (zh) * | 2021-12-16 | 2022-04-12 | 首都医科大学 | 一种头部畸形伴神经-运动障碍动物模型的建立方法 |
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| US6437215B1 (en) * | 1999-06-28 | 2002-08-20 | Massachusetts Institute Of Technology | SR-BI and ApoE knockout animals and use thereof as models for atherosclerosis and heart attack |
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2018
- 2018-04-28 WO PCT/CN2018/085097 patent/WO2018196874A1/zh active Application Filing
- 2018-04-28 CN CN201880028071.9A patent/CN110691512B/zh active Active
- 2018-04-28 US US16/609,110 patent/US11882816B2/en active Active
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| CN110205375A (zh) * | 2019-06-26 | 2019-09-06 | 宁夏医科大学 | 一种动脉粥样硬化诊断用分子标志物及其应用 |
| CN114304064A (zh) * | 2021-12-16 | 2022-04-12 | 首都医科大学 | 一种头部畸形伴神经-运动障碍动物模型的建立方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110691512B (zh) | 2021-11-09 |
| WO2018196874A1 (zh) | 2018-11-01 |
| US20200077632A1 (en) | 2020-03-12 |
| US11882816B2 (en) | 2024-01-30 |
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