CN110526925A - 一种25β-仲丁烯基-23β-异丁酰氧基米尔贝霉素衍生物的分离方法及其应用 - Google Patents
一种25β-仲丁烯基-23β-异丁酰氧基米尔贝霉素衍生物的分离方法及其应用 Download PDFInfo
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- CN110526925A CN110526925A CN201910641730.2A CN201910641730A CN110526925A CN 110526925 A CN110526925 A CN 110526925A CN 201910641730 A CN201910641730 A CN 201910641730A CN 110526925 A CN110526925 A CN 110526925A
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- mibemycin
- derivative
- isobutyl acyloxy
- cyclobutenyl
- ethyl acetate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
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CN201910641730.2A CN110526925B (zh) | 2019-07-16 | 2019-07-16 | 一种25β-仲丁烯基-23β-异丁酰氧基米尔贝霉素衍生物的分离方法及其应用 |
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CN201910641730.2A CN110526925B (zh) | 2019-07-16 | 2019-07-16 | 一种25β-仲丁烯基-23β-异丁酰氧基米尔贝霉素衍生物的分离方法及其应用 |
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CN110526925A true CN110526925A (zh) | 2019-12-03 |
CN110526925B CN110526925B (zh) | 2021-10-12 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116589606A (zh) * | 2022-12-01 | 2023-08-15 | 中国药科大学 | 一种丁酰化酵母葡聚糖及其制备方法、应用 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5055596A (en) * | 1987-11-03 | 1991-10-08 | Beecham Group P.L.C. | Derivatives of avermectin and milbemycin |
US20010002401A1 (en) * | 1998-05-22 | 2001-05-31 | Nigel A Evans | Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives |
CN101037442A (zh) * | 2007-01-17 | 2007-09-19 | 东北农业大学 | 用冰城链霉菌制备的新化合物及制备方法 |
US20140080779A1 (en) * | 2011-05-02 | 2014-03-20 | Universite De Geneve | Macrocyclic lactones and use thereof |
CN106167494A (zh) * | 2016-06-03 | 2016-11-30 | 遵义医学院 | 卤化ii型聚酮类抗生素化合物、制备方法及其应用 |
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2019
- 2019-07-16 CN CN201910641730.2A patent/CN110526925B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5055596A (en) * | 1987-11-03 | 1991-10-08 | Beecham Group P.L.C. | Derivatives of avermectin and milbemycin |
US20010002401A1 (en) * | 1998-05-22 | 2001-05-31 | Nigel A Evans | Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives |
CN101037442A (zh) * | 2007-01-17 | 2007-09-19 | 东北农业大学 | 用冰城链霉菌制备的新化合物及制备方法 |
US20140080779A1 (en) * | 2011-05-02 | 2014-03-20 | Universite De Geneve | Macrocyclic lactones and use thereof |
CN106167494A (zh) * | 2016-06-03 | 2016-11-30 | 遵义医学院 | 卤化ii型聚酮类抗生素化合物、制备方法及其应用 |
Non-Patent Citations (3)
Title |
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BAKER, GH ET AL.: "Further novel milbemycin antibiotics from Streptomyces sp E225 fermentation, isolation and structure elucidation", 《JOURNAL OF ANTIBIOTICS》 * |
林秀萍: "米尔贝霉素的产生菌、理化性质、生物学活性及应用研究进展", 《中国抗生素杂志》 * |
田鹏等: "链霉菌Streptomyces sp. FJS31-2次级代谢产物UK-78623的分离鉴定及抑菌活性研究", 《中国酿造》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116589606A (zh) * | 2022-12-01 | 2023-08-15 | 中国药科大学 | 一种丁酰化酵母葡聚糖及其制备方法、应用 |
CN116589606B (zh) * | 2022-12-01 | 2024-05-28 | 中国药科大学 | 一种丁酰化酵母葡聚糖及其制备方法、应用 |
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CN110526925B (zh) | 2021-10-12 |
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Inventor after: Li Xiaoqian Inventor after: Liu Tie Inventor after: Yue Changwu Inventor after: Xu Wenhui Inventor after: Huang Yanjie Inventor after: Lv Yuhong Inventor after: Tian Peng Inventor before: Liu Tie Inventor before: Li Xiaoqian Inventor before: Yue Changwu Inventor before: Xu Wenhui Inventor before: Huang Yanjie Inventor before: Lv Yuhong Inventor before: Tian Peng |
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