CN110522695B - Private skin cleaning bath salt and preparation method and application thereof - Google Patents
Private skin cleaning bath salt and preparation method and application thereof Download PDFInfo
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- CN110522695B CN110522695B CN201910913201.3A CN201910913201A CN110522695B CN 110522695 B CN110522695 B CN 110522695B CN 201910913201 A CN201910913201 A CN 201910913201A CN 110522695 B CN110522695 B CN 110522695B
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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Abstract
The invention provides a private skin cleaning bath salt, which is prepared from the raw materials of salt and a traditional Chinese medicine composition; the traditional Chinese medicine composition comprises the following preparation raw materials in parts by weight: 5-15 parts of radix sophorae flavescentis, 5-15 parts of golden cypress, 5-10 parts of curcuma zedoary, 5-10 parts of honeysuckle, 1-5 parts of fructus cnidii, 1-3 parts of rheum officinale and 1-3 parts of dandelion. The traditional Chinese medicine composition selected from the private part skin cleaning bath salt disclosed by the invention takes radix sophorae flavescentis and golden cypress as monarch drugs, curcuma zedoary and honeysuckle as ministerial drugs, fructus cnidii as an adjuvant drug and rheum officinale and dandelion as conductant drugs, and the traditional Chinese medicine components are matched with each other, so that a synergistic interaction effect is achieved, the private part can be effectively cleaned, harmful bacteria can be inhibited and killed, and the private part physiological environment can be adjusted and balanced.
Description
Technical Field
The invention belongs to the field of daily chemical washing and care products, and particularly relates to private skin cleaning bath salt and a preparation method and application thereof.
Background
The female private parts are important organs for metabolic secretion, the vaginal orifice is a portal of two systems of reproduction and urinary, and the female genital tract is easy to be infected with various germs and cause diseases due to the physiological weakness of the female genital tract. Due to pruritus vulvae, leucorrhea with reddish discharge, condyloma, erosion and the like caused by vaginitis, cervicitis, pelvic inflammation and the like caused by pathogenic bacteria infection, the female suffers from insanity, if the female is prevented and treated in time, not only the physical and mental health and the life quality of the female are affected, but also infertility can be caused. There are two main types of female personal care products available on the market: medicinal lotion with therapeutic function and personal care product with cleaning and sterilizing functions. The former can treat gynecological diseases, but almost does not contain other components except Chinese herbal medicine extract such as surfactant, and only contains medicinal components, and has no cleaning function; although the latter can clean and sterilize, the latter is mainly prepared from a surfactant with a cleaning effect and a bactericide with a sterilizing effect, and the strong cleaning and sterilizing capability can destroy the self-cleaning effect of the body, reduce the immunity of the body, stimulate the skin, destroy the self-acidic environment of the body, break the pH range for maintaining the health of the private parts of women, cause dysbacteriosis and cause gynecological diseases.
CN106691969A discloses a female private gel containing a traditional Chinese medicine composition, wherein the traditional Chinese medicine composition in the female private gel comprises the following raw materials in parts by weight: 30-40 parts of fig, 20-30 parts of pomegranate bark, 15-30 parts of curcuma zedoary, 35-50 parts of sophora flavescens and 10-20 parts of agrimony bud. The gel has high concentration, can be used for local sterilization and treatment of vaginitis, but daily use causes dysbacteriosis and cannot be used for daily cleaning and nursing.
CN103446439A discloses a traditional Chinese medicine composition for preparing a cleaning lotion for female private parts and a preparation method thereof, wherein the traditional Chinese medicine composition for preparing the cleaning lotion for female private parts is mainly prepared from the following eight raw materials, by weight, 5-20 parts of saussurea involucrate, 5-25 parts of radix sophorae flavescentis, 5-25 parts of fructus cnidii, 5-25 parts of aloe, 5-20 parts of rose, 5-20 parts of orchid, 5-20 parts of goldenseal and 5-25 parts of radish seed. The traditional Chinese medicine composition prepared by the invention has the functions of sterilizing, diminishing inflammation and contracting vagina, but has lower cleaning effect on private parts and larger irritation.
CN106580791A discloses a Chinese medicinal composition, which comprises: cactus extract, coptis chinensis extract, angelica sinensis extract, oldenlandia diffusa extract, polygonum hydropiper extract, perilla extract, isatis root extract, prinsepia utilis royle extract and Chinese violet extract. Although the invention can effectively clean private parts and has the functions of mildly nourishing, the invention has poor effects of removing odor, relieving itching, sterilizing and diminishing inflammation.
Therefore, the development of a cleaning and nursing product which is mild and non-irritant, can effectively clean private parts, inhibits and kills harmful bacteria and balances private and nascent physiological environments has important significance.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide the private skin cleaning bath salt, and the preparation method and the application thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
in a first aspect, the invention provides private skin cleaning bath salt which is prepared from raw materials including salt and a traditional Chinese medicine composition;
the traditional Chinese medicine composition comprises the following preparation raw materials in parts by weight: 5-15 parts of radix sophorae flavescentis, 5-15 parts of golden cypress, 5-10 parts of curcuma zedoary, 5-10 parts of honeysuckle, 1-5 parts of fructus cnidii, 1-3 parts of rheum officinale and 1-3 parts of dandelion.
In the raw materials for preparing the traditional Chinese medicine composition, the content of the radix sophorae flavescentis is 5-15 parts, such as 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts and 15 parts.
In the raw materials for preparing the Chinese medicinal composition, the content of phellodendron bark is 5-15 parts, for example, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts and 15 parts.
The content of Curcumae rhizoma in the raw materials for preparing the Chinese medicinal composition is 5-10 parts, such as 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts.
In the raw materials for preparing the traditional Chinese medicine composition, the honeysuckle is 5-10 parts, for example, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts and 10 parts.
In the preparation raw materials of the traditional Chinese medicine composition, the content of the common cnidium fruit is 1 to 5 parts, for example, 1 part, 2 parts, 3 parts, 4 parts and 5 parts.
The content of radix et rhizoma Rhei in the raw materials for preparing the Chinese medicinal composition is 1-3 parts, such as 1 part, 2 parts, and 3 parts.
In the preparation raw materials of the traditional Chinese medicine composition, the content of the dandelion is 1-3 parts, for example, 1 part, 2 parts and 3 parts.
In the invention, the lightyellow sophora root and the amur corktree bark are both monarch drugs. The traditional Chinese medicine considers the nature and taste of the kuh-seng: bitter taste and cold nature. Clear heat and dry dampness, kill parasites and relieve itching, and induce diuresis. Also has obvious effect on female trichomonas vaginitis. The ether extract and alcohol extract contained in the liquid have strong bacteriostatic action on staphylococcus aureus, while the sophora flavescens aqueous extract has inhibitory action on trichophyton violaceum, trichophyton concentricum, trichophyton schoenleinii, trichophyton ovate, etc. It has tranquilizing and mild pain relieving effects. The traditional Chinese medicine considers the nature and taste of the phellodendron bark: bitter taste and cold nature. Clear heat and dry dampness, purge fire and remove steam, remove toxicity and cure sore. Has effects of eliminating pyocutaneous disease pyogenic infection, eczema and pruritus, and has strong inhibitory effect on various dysentery bacilli. Therefore, the radix sophorae flavescentis and the golden cypress are monarch drugs together, can effectively clean private parts and inhibit and kill harmful bacteria, and has good relieving effect on sensitive skin and effect of treating skin diseases.
The zedoary and the honeysuckle are used as ministerial drugs. The traditional Chinese medicine is regarded as the nature and taste of the zedoary: bitter taste and warm nature. Break blood and move qi, resolve food stagnation and alleviate pain. Dispel wind and dampness, relieve swelling and alleviate pain. Can be used for treating rheumatalgia, headache, chest pain, hypochondriac pain, and diarrhea pain; it is indicated for traumatic injury, swelling and pain due to blood stasis by external application. The traditional Chinese medicine considers that the honeysuckle is sweet in taste and cold in nature. The honeysuckle can actually have a certain inhibiting effect on inhibiting various pathogenic bacteria, particularly on avoiding staphylococcus aureus, hemolytic streptococcus, escherichia coli, dysentery bacillus and the like.
The common cnidium fruit is used as an adjuvant: the traditional Chinese medicine considers that the fructus cnidii has the following properties and tastes: warm in nature and bitter in taste. Has the effects of eliminating dampness, dispelling pathogenic wind, killing parasites, warming kidney and tonifying yang; osthole has good anti-inflammatory and antiallergic effects, and has good therapeutic effect on skin pruritus such as eczema, prurigo, urticaria and the like, especially has excellent effect on externally treating trichomonas vaginitis, but the skin diseases are differentiated by blood heat, dampness and heat, so that fructus Cnidii is used as a messenger drug, and can resist allergy and allergic reaction. Thereby assisting the monarch drug to exert the efficacy, clearing away heat and toxic material, resisting allergy and relieving itching, dispelling wind and relieving convulsion, promoting blood circulation and promoting granulation, repairing skin allergy problems and promoting the recovery of skin barrier function.
Rhubarb and dandelion are used as guiding drugs: according to traditional Chinese medicine, the rhubarb has the following characteristic: cold in nature and bitter in taste. It enters spleen, stomach, large intestine, liver and pericardium meridians. Has effects in purging pathogenic accumulation, clearing away heat, purging pathogenic fire, cooling blood, removing toxic materials, dispelling blood stasis, dredging channels, promoting diuresis, and eliminating jaundice; in addition, rhubarb can solidify capillary vessels through the proliferation of vascular endothelial cells, reduce the generation of red blood filaments and better improve the skin immunity. According to traditional Chinese medicine, dandelion is considered to have the following properties and tastes: cold in nature and sweet in taste. Has excellent effect of cleaning blood for improving eczema, relieving dermatitis and joint discomfort. Therefore, the rhubarb and the dandelion are used as guiding drugs together, have multiple effects of resisting inflammation, repairing damaged skin and the like, and can also synergistically regulate the toxic and side effects of the traditional Chinese medicine composition and reduce the irritation of traditional Chinese medicine components.
The seven traditional Chinese medicine components are combined, have the synergistic effect, can well clear away heat and toxic materials, relieve swelling, relieve itching, promote blood circulation, promote tissue regeneration, repair and diminish inflammation, are mild and non-irritant, and can effectively clean private parts, inhibit and kill harmful bacteria and balance private and nascent physiological environment.
Preferably, the mass ratio of the salt to the raw materials for preparing the traditional Chinese medicine composition is (3-8) to 1, and can be 3:1, 4:1, 5:1, 6:1, 7:1 and 8: 1.
Preferably, the salt comprises any one of sea salt, kosher salt, himalayan rock salt, black salt, pottery salt, Persian blue salt or salt flower or a combination of at least two of the same.
Preferably, the raw materials for preparing the traditional Chinese medicine composition also comprise adjuvants;
preferably, the mass ratio of the adjuvant to the raw materials for preparing the traditional Chinese medicine composition is (0.02-0.1):1, and can be, for example, 0.02:1, 0.03:1, 0.04:1, 0.05:1, 0.06:1, 0.07:1, 0.08:1, 0.09:1 and 0.1: 1.
Preferably, the adjuvant is selected from any one or a combination of at least two of fructus kochiae, rhizoma atractylodis, radix stemonae, pepper, coptis chinensis, cortex dictamni, polygonum cuspidatum, rehmannia glutinosa, angelica sinensis, salvia miltiorrhiza, periostracum cicada, liquorice or scutellaria baicalensis.
Preferably, the raw materials for preparing the bath salt also comprise a surfactant.
Preferably, the content of the surfactant in the bath salt is 1 to 10% by mass, and may be, for example, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%.
Preferably, the surfactant is selected from any one of sodium fatty acid, alkyl glycoside, sodium alpha-olefin sulfonate, sodium fatty acid methyl ester sulfonate or dodecylamine ethyl glycine or a combination of at least two of the same.
Preferably, the raw materials for preparing the bath salt also comprise a penetration enhancer.
Preferably, the bath salt contains the penetration enhancer in an amount of 0.5 to 2% by mass, for example, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, 1.2%, 1.4%, 1.6%, 1.8%, 2%.
Preferably, the penetration enhancer is selected from any one or a combination of at least two of borneol, menthol, aromatic oil, azone or thiaketone.
Preferably, the raw materials for preparing the bath salt also comprise perfume.
Preferably, the bath salt contains the perfume in an amount of 0.1-0.5% by mass, for example, 0.1%, 0.2%, 0.3%, 0.4%, 0.5%.
Preferably, the perfume is selected from any one or combination of at least two of jasmine extract, vanilla tincture, vanilla balsam, peppermint oil, lavender essential oil, chamomile essential oil or rose essential oil.
In a second aspect, the present invention provides a method for preparing the private skin cleansing bath salt according to the first aspect, wherein the method for preparing the bath salt comprises the following steps:
(1) sieving salt: grinding the selected salt, and sieving to obtain fine salt;
(2) traditional Chinese medicine pretreatment: pulverizing and mixing the components of the Chinese medicinal composition, extracting, and concentrating to obtain Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding water to prepare paste, concentrating and drying to obtain the private skin cleaning bath salt.
Preferably, the particle size of the fine salt in step (1) is 100-200 meshes, for example, 100 meshes, 110 meshes, 120 meshes, 130 meshes, 140 meshes, 150 meshes, 160 meshes, 170 meshes, 180 meshes, 200 meshes can be adopted.
Preferably, the particle size of the pulverized and mixed traditional Chinese medicine composition in the step (2) is 100-500 meshes, for example, 100 meshes, 150 meshes, 200 meshes, 250 meshes, 300 meshes, 350 meshes, 400 meshes, 450 meshes, 500 meshes.
Preferably, the extraction in step (2) specifically comprises the following steps: adding an extraction solvent into the crushed and mixed traditional Chinese medicine composition, soaking, separating and concentrating to obtain a concentrated solution, thus obtaining the traditional Chinese medicine extract.
Preferably, the extraction solvent comprises water and/or ethanol.
Preferably, the mass ratio of the extraction solvent to the traditional Chinese medicine composition is (1-10):1, for example, 1:1, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10: 1.
Preferably, the soaking time is 1-5h, for example, 1h, 2h, 3h, 4h, 5 h.
Preferably, the temperature of the soaking is 40-80 deg.C, such as 40 deg.C, 45 deg.C, 50 deg.C, 55 deg.C, 60 deg.C, 65 deg.C, 70 deg.C, 75 deg.C, 80 deg.C.
Preferably, the separation is a centrifugation.
Preferably, the concentration in step (2) further comprises the purification of the traditional Chinese medicine extract.
Preferably, the purification method is purification using a macroporous resin.
Preferably, the macroporous resin has a particle size of 20 to 50 meshes, for example, 20 meshes, 25 meshes, 30 meshes, 35 meshes, 40 meshes, 45 meshes, 50 meshes.
Preferably, the macroporous resin is selected from any one or a combination of at least two of AB-8, D1300 or D101.
Preferably, the temperature of the paste preparation in the step (3) is 40-80 ℃, and may be, for example, 40 ℃, 45 ℃, 50 ℃, 55 ℃, 60 ℃, 65 ℃, 70 ℃, 75 ℃ and 80 ℃.
Preferably, the drying of step (3) is vacuum drying.
Preferably, the drying temperature in step (3) is 10-30 deg.C, 10 deg.C, 12 deg.C, 14 deg.C, 16 deg.C, 18 deg.C, 20 deg.C, 22 deg.C, 24 deg.C, 26 deg.C, 28 deg.C, 30 deg.C.
Preferably, the preparation method of the bath salt comprises the following steps:
(1) sieving salt: grinding the selected salt, and sieving to obtain fine salt;
(2) traditional Chinese medicine pretreatment: pulverizing and mixing the components of the Chinese medicinal composition and adjuvants, extracting, and concentrating to obtain Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding a surfactant, a penetration enhancer and a spice, uniformly mixing, adding water to prepare paste, concentrating and drying to obtain the private skin cleaning bath salt.
Preferably, the preparation method of the bath salt comprises the following steps:
(1) sieving salt: grinding and sieving the selected salt to obtain 200-mesh fine salt with the granularity of 100-;
(2) traditional Chinese medicine pretreatment: crushing the components and the adjuvant in the traditional Chinese medicine composition into 100-500 meshes, adding an extraction solvent into the crushed and mixed traditional Chinese medicine composition and adjuvant, wherein the mass ratio of the extraction solvent to the traditional Chinese medicine composition is (1-10) and soaking the traditional Chinese medicine composition for 1-5h at 40-80 ℃, and performing centrifugal separation and concentration to obtain a concentrated solution, thus obtaining the traditional Chinese medicine extract;
(3) mixing the fine salt and the Chinese medicinal extract, adding surfactant, penetration enhancer and perfume, mixing, adding water at 40-80 deg.C to obtain paste, concentrating, and drying to obtain the private skin cleaning bath salt.
In a third aspect, the present invention provides the use of a personal cleansing bath salt according to the first aspect, in the manufacture of a female personal care product.
Compared with the prior art, the invention has the following beneficial effects:
(1) the traditional Chinese medicine composition selected from the private skin-cleaning bath salt disclosed by the invention takes radix sophorae flavescentis and golden cypress as monarch drugs, curcuma zedoary and honeysuckle as ministerial drugs, fructus cnidii as an adjuvant drug, and rheum officinale and dandelion as conductant drugs, and the traditional Chinese medicine components are matched with each other, so that a synergistic interaction effect is achieved, the private skin-cleaning bath salt can effectively clean private parts, inhibit and kill harmful bacteria, and balance private and primary physiological environments.
(2) The private skin cleaning bath salt disclosed by the invention can effectively clean private parts, is safe and non-irritant, does not damage the skin mucous membrane of the private parts, can adjust the environmental balance of the flora of the private parts, inhibits the breeding of staphylococcus aureus, escherichia coli and candida albicans, has the effects of sterilizing, diminishing inflammation, relieving itching and removing peculiar smell, does not generate drug resistance after being used for a long time, has the effect of assisting in beautifying the private parts, and can effectively prevent the occurrence and recurrence of private diseases.
Detailed Description
The technical solution of the present invention is further explained by the following embodiments. It should be understood by those skilled in the art that the examples are only for the understanding of the present invention and should not be construed as the specific limitations of the present invention.
Example 1
The embodiment provides a private skin cleaning bath salt which is prepared from the raw materials of 165g of sea salt, 15g of radix sophorae flavescentis, 15g of golden cypress, 8g of curcuma zedoary, 8g of honeysuckle, 5g of fructus cnidii, 2g of rheum officinale and 2g of dandelion.
The preparation method of the bath salt comprises the following steps:
(1) sieving salt: grinding sea salt, and sieving to obtain fine salt with particle size of 100 mesh;
(2) traditional Chinese medicine pretreatment: pulverizing the components of the traditional Chinese medicine composition into powder with the granularity of 100 meshes, mixing, adding ethanol into the pulverized and mixed traditional Chinese medicine composition, wherein the mass ratio of the ethanol to the traditional Chinese medicine composition is 5: 1; soaking at 80 deg.C for 1h, centrifuging, concentrating, and purifying with AB-8 macroporous resin with particle size of 20 meshes to obtain the Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding water at 80 ℃ to prepare paste, concentrating, and vacuum drying at 20 ℃ to obtain the private skin cleaning bath salt.
Example 2
The embodiment provides a private skin cleaning bath salt which is prepared from 165g of black salt, 10g of radix sophorae flavescentis, 10g of golden cypress, 10g of curcuma zedoary, 10g of honeysuckle, 5g of fructus cnidii, 1g of rheum officinale and 1g of dandelion.
The preparation method of the bath salt comprises the following steps:
(1) sieving salt: grinding sea salt, and sieving to obtain fine salt with particle size of 200 mesh;
(2) traditional Chinese medicine pretreatment: pulverizing the components of the traditional Chinese medicine composition into powder with the granularity of 500 meshes, mixing, adding ethanol into the pulverized and mixed traditional Chinese medicine composition, wherein the mass ratio of the ethanol to the traditional Chinese medicine composition is 10: 1; soaking at 40 deg.C for 5h, centrifuging, concentrating, and purifying with D1300 macroporous resin with particle size of 50 mesh to obtain the Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding water at 40 ℃ to prepare paste, concentrating, and drying in vacuum at 30 ℃ to obtain the private skin cleaning bath salt.
Example 3
The embodiment provides a private skin cleaning bath salt which is prepared from raw materials including 300g of Persian blue salt, 15g of radix sophorae flavescentis, 10g of golden cypress, 10g of rhizoma zedoariae, 5g of honeysuckle, 4g of fructus cnidii, 3g of rheum officinale and 3g of dandelion.
The preparation method of the bath salt comprises the following steps:
(1) sieving salt: grinding sea salt, and sieving to obtain fine salt with particle size of 150 mesh;
(2) traditional Chinese medicine pretreatment: pulverizing the components of the traditional Chinese medicine composition into powder with the granularity of 200 meshes, mixing, adding ethanol into the pulverized and mixed traditional Chinese medicine composition, wherein the mass ratio of the ethanol to the traditional Chinese medicine composition is 3: 1; soaking at 40 deg.C for 5h, centrifuging, concentrating, and purifying with D1300 macroporous resin with particle size of 50 mesh to obtain the Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding water at 80 ℃ to prepare paste, concentrating, and drying in vacuum at 10 ℃ to obtain the private skin cleaning bath salt.
Example 4
The embodiment provides a private skin cleaning bath salt which is prepared from the raw materials of 300g of sea salt, 15g of radix sophorae flavescentis, 10g of golden cypress, 10g of curcuma zedoary, 5g of honeysuckle, 4g of fructus cnidii, 3g of rheum officinale, 3g of dandelion, 7g of sodium fatty acid, 2g of borneol and 0.5g of jasmine extract.
The preparation method of the bath salt comprises the following steps:
(1) sieving salt: grinding sea salt, and sieving to obtain fine salt with particle size of 150 mesh;
(2) traditional Chinese medicine pretreatment: pulverizing the components of the traditional Chinese medicine composition into powder with the granularity of 200 meshes, mixing, adding ethanol into the pulverized and mixed traditional Chinese medicine composition, wherein the mass ratio of the ethanol to the traditional Chinese medicine composition is 3: 1; soaking at 40 deg.C for 5h, centrifuging, concentrating, and purifying with D1300 macroporous resin with particle size of 50 mesh to obtain the Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding sodium aliphatate, borneol and jasmine extract, uniformly mixing, adding water at 80 ℃ to prepare paste, concentrating, and drying in vacuum at 10 ℃ to obtain the private skin cleaning bath salt.
Example 5
The embodiment provides a private skin cleaning bath salt which is prepared from raw materials including 350g of sea salt, 12g of radix sophorae flavescentis, 12g of golden cypress, 10g of curcuma zedoary, 8g of honeysuckle, 4g of fructus cnidii, 2g of rheum officinale, 2g of dandelion, 20g of alkyl glycoside, 5g of menthol and 2g of vanilla balsam.
The preparation method of the bath salt comprises the following steps:
(1) sieving salt: grinding sea salt, and sieving to obtain fine salt with particle size of 100 mesh;
(2) traditional Chinese medicine pretreatment: pulverizing the components of the traditional Chinese medicine composition into powder with the granularity of 300 meshes, mixing, adding ethanol into the pulverized and mixed traditional Chinese medicine composition, wherein the mass ratio of the ethanol to the traditional Chinese medicine composition is 6: 1; soaking at 80 deg.C for 3h, centrifuging, concentrating, and purifying with D1300 macroporous resin with particle size of 40 mesh to obtain the Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding alkyl glycoside, menthol and vanillina alba, uniformly mixing, adding water at 80 ℃ to prepare paste, concentrating, and drying in vacuum at 20 ℃ to obtain the private skin cleaning bath salt.
Example 6
The embodiment provides a private skin cleaning bath salt which is prepared from the raw materials of 400g of sea salt, 10g of radix sophorae flavescentis, 15g of golden cypress, 8g of curcuma zedoary, 10g of honeysuckle, 5g of fructus cnidii, 1g of rheum officinale, 1g of dandelion, 30g of dodecylamine ethyl glycine, 8g of azone and 2g of lavender essential oil.
The preparation method of the bath salt comprises the following steps:
(1) sieving salt: grinding sea salt, and sieving to obtain fine salt with particle size of 200 mesh;
(2) traditional Chinese medicine pretreatment: pulverizing the components of the traditional Chinese medicine composition into powder with the granularity of 100 meshes, mixing, adding ethanol into the pulverized and mixed traditional Chinese medicine composition, wherein the mass ratio of the ethanol to the traditional Chinese medicine composition is 10: 1; soaking at 60 deg.C for 4h, centrifuging, concentrating, and purifying with D1300 macroporous resin with particle size of 30 meshes to obtain the Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding sodium aliphatate, borneol and jasmine extract, uniformly mixing, adding water at 60 ℃ to prepare paste, concentrating, and drying in vacuum at 20 ℃ to obtain the private skin cleaning bath salt.
Example 7
The embodiment provides a private skin cleaning bath salt which is prepared from the raw materials of 400g of sea salt, 10g of radix sophorae flavescentis, 15g of golden cypress, 8g of curcuma zedoary, 10g of honeysuckle, 5g of fructus cnidii, 1g of rheum officinale, 1g of dandelion, 1g of fructus kochiae, 30g of dodecylamine ethyl glycine, 8g of azone and 2g of lavender essential oil.
The preparation method of the bath salt comprises the following steps:
(1) sieving salt: grinding sea salt, and sieving to obtain fine salt with particle size of 200 mesh;
(2) traditional Chinese medicine pretreatment: pulverizing the components of the traditional Chinese medicine composition and an adjuvant, namely fructus kochiae into powder with the granularity of 100 meshes, mixing, adding ethanol into the pulverized and mixed traditional Chinese medicine composition, wherein the mass ratio of the ethanol to the traditional Chinese medicine composition is 10: 1; soaking at 60 deg.C for 4h, centrifuging, concentrating, and purifying with D1300 macroporous resin with particle size of 30 meshes to obtain the Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding sodium aliphatate, borneol and jasmine extract, uniformly mixing, adding water at 60 ℃ to prepare paste, concentrating, and drying in vacuum at 20 ℃ to obtain the private skin cleaning bath salt.
Example 8
The embodiment provides a private skin cleaning bath salt which is prepared from the raw materials of 400g of sea salt, 10g of radix sophorae flavescentis, 15g of golden cypress, 8g of curcuma zedoary, 10g of honeysuckle, 5g of fructus cnidii, 1g of rheum officinale, 1g of dandelion, 1g of rhizoma atractylodis, 30g of dodecylamine ethyl glycine, 8g of azone and 2g of lavender essential oil.
The preparation method of the bath salt comprises the following steps:
(1) sieving salt: grinding sea salt, and sieving to obtain fine salt with particle size of 200 mesh;
(2) traditional Chinese medicine pretreatment: pulverizing the components of the traditional Chinese medicine composition and an adjuvant, namely fructus kochiae into powder with the granularity of 100 meshes, mixing, adding ethanol into the pulverized and mixed traditional Chinese medicine composition, wherein the mass ratio of the ethanol to the traditional Chinese medicine composition is 10: 1; soaking at 60 deg.C for 4h, centrifuging, concentrating, and purifying with D1300 macroporous resin with particle size of 30 meshes to obtain the Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding sodium aliphatate, borneol and jasmine extract, uniformly mixing, adding water at 60 ℃ to prepare paste, concentrating, and drying in vacuum at 20 ℃ to obtain the private skin cleaning bath salt.
Comparative example 1
The bath salt is prepared by the same method as in example 1, except that the bath salt is prepared from 165g of sea salt and 55g of radix sophorae flavescentis.
Comparative example 2
The same as example 1 except that the bath salt was prepared from 165g of sea salt and 55g of phellodendron amurense, and the preparation method was the same as example 1.
Comparative example 3
The same as example 1, except that the bath salt is prepared from the raw materials including 165g of sea salt and 55g of zedoary, and the preparation method is the same as example 1.
Comparative example 4
The bath salt is prepared by the same method as in example 1, except that the bath salt is prepared from 165g of sea salt and 55g of honeysuckle.
Comparative example 5
The bath salt is prepared by the same method as in example 1, except that the bath salt is prepared from 165g of sea salt and 55g of fructus cnidii.
Comparative example 6
The same as example 1 except that the bath salt was prepared from the raw materials including sea salt 165g and rhubarb 55g, and the preparation method was the same as example 1.
Comparative example 7
The same as example 1, except that the bath salt was prepared from the raw materials including 165g of sea salt and 55g of dandelion, and the preparation method was the same as example 1.
Comparative example 8
The bath salt is prepared from 165g of sea salt, 30g of golden cypress, 8g of curcuma zedoary, 8g of honeysuckle, 5g of common cnidium fruit, 2g of rhubarb and 2g of dandelion in the same manner as in example 1.
Comparative example 9
The bath salt is prepared from the raw materials including 165g of sea salt, 30g of radix sophorae flavescentis, 8g of curcuma zedoary, 8g of honeysuckle, 5g of fructus cnidii, 2g of rheum officinale and 2g of dandelion in the same manner as in example 1.
Comparative example 10
The bath salt is prepared from the raw materials including 165g of sea salt, 15g of radix sophorae flavescentis, 15g of cortex phellodendri, 16g of curcuma zedoary, 5g of fructus cnidii, 2g of rheum officinale and 2g of dandelion in the same manner as in example 1.
Comparative example 11
The bath salt is prepared from the raw materials including 165g of sea salt, 15g of radix sophorae flavescentis, 15g of cortex phellodendri, 16g of honeysuckle, 5g of fructus cnidii, 2g of rheum officinale and 2g of dandelion in the same manner as in example 1.
Comparative example 12
The bath salt is prepared from 165g of sea salt, 20g of radix sophorae flavescentis, 15g of cortex phellodendri, 8g of curcuma zedoary, 8g of honeysuckle, 2g of rheum officinale and 2g of dandelion.
Comparative example 13
The bath salt is prepared from 165g of sea salt, 15g of radix sophorae flavescentis, 15g of cortex phellodendri, 8g of curcuma zedoary, 8g of honeysuckle, 5g of fructus cnidii and 2g of dandelion.
Comparative example 14
The bath salt is prepared from 165g of sea salt, 15g of radix sophorae flavescentis, 15g of cortex phellodendri, 8g of curcuma zedoary, 8g of honeysuckle, 5g of fructus cnidii and 2g of rheum officinale.
Comparative example 15
The bath salt is prepared from 100g of sea salt, 15g of radix sophorae flavescentis, 15g of cortex phellodendri, 8g of curcuma zedoary, 8g of honeysuckle, 5g of fructus cnidii, 2g of rheum officinale and 2g of dandelion.
Comparative example 16
The bath salt is prepared from the raw materials of 600g of sea salt, 15g of radix sophorae flavescentis, 15g of cortex phellodendri, 8g of curcuma zedoary, 8g of honeysuckle, 5g of fructus cnidii, 2g of rheum officinale and 2g of dandelion in the same manner as in example 1.
Test example 1
Haemolysis test of erythrocytes
The erythrocyte hemolysis test is one of the alternatives of the rabbit eye irritation test (Draize test), and the basic principle is to evaluate the damage of chemicals to eye tissue cells by measuring the dissolution amount and denaturation degree of hemoglobin. The RBC test is used internationally for evaluating eye irritation studies on chemicals such as cosmetics and raw materials.
The bath salts prepared in examples 1 to 8 and the bath salts prepared in comparative examples 1 to 16 were subjected to a red blood cell hemolysis test in accordance with the RBC test method and grade standard of the European Alternatives validation center (ECVAM). ECVAM. ECVAM DB-ALM INVITOX Protoco, Red blood cells test system INVITOX No.37 Ispra. Italy ECVAM,1994 ], ECVAM cosmetic products RBC experimental irritation grading criteria are shown in Table 1:
TABLE 1
The results of the hemolysis test of erythrocytes with the bath salts prepared in examples 1 to 8 and the bath salts prepared in comparative examples 1 to 16 are shown in Table 2, in which HD is measured50The concentration of the sample at which 50% of erythrocytes are hemolyzed, DI is the protein denaturation index, and L/D is HD50Ratio to DI.
TABLE 2
From the above test results, it can be seen that the bath salts prepared in examples 1 to 8 of the present invention are classified as non-irritating, which indicates that the bath salts prepared in the present invention are both mild and non-irritating; among them, the bath salts prepared in examples 1 to 8 had a sample concentration HD at which 50% of erythrocytes were hemolyzed50HD much larger than that of bath salts prepared in comparative examples 1 to 1650Meanwhile, the protein denaturation index DI is also obviously smaller than that of the bath salt prepared in comparative examples 1-16, which shows that seven traditional Chinese medicine components of the bath salt are mutually matched, so that the toxic and side effects and irritation of the traditional Chinese medicines can be obviously reduced after synergistic interaction, and the traditional Chinese medicine composition disclosed by the invention is scientific and reasonable in component matching.
Test example 2
In vitro antibacterial Performance test
Taking the bath salt prepared in the embodiments 1-8 and the bath salt prepared in the proportions 1-16, adding hot water, stirring until the bath salt is dissolved, standing, taking clinical isolated strains of staphylococcus aureus, escherichia coli and candida albicans, respectively culturing the clinical isolated strains in a culture medium, and operating according to the national standard GB15979-2002, wherein the detection results are shown in the table 3, and the table 3 is the in-vitro antibacterial performance test result of the private care product prepared in the embodiment of the invention.
TABLE 3
As can be seen from the data in Table 3, the bath salt prepared in the examples 1 to 8 can effectively inhibit the growth of Staphylococcus aureus, Escherichia coli and Candida albicans, has significant antibacterial activity, can reach a bacteriostasis rate of more than 99% after acting for 2min, and can maintain the balance of private flora. Compared with bath salts containing only a single traditional Chinese medicine component in comparative examples 1-7 and bath salts lacking any traditional Chinese medicine component in comparative examples 8-14, the bath salts can only reach 89% even after 20min of action, and have much lower inhibition rate on staphylococcus aureus, escherichia coli and candida albicans than the bath salts prepared by the application. The seven traditional Chinese medicine components of the bath salt are matched with each other, and the synergistic effect can adjust the environmental balance of the flora in private parts, so that the effect of inhibiting the breeding of staphylococcus aureus, escherichia coli and candida albicans is achieved.
Test example 3
Clinical efficacy testing
720 women, 25-55 years old, were selected and divided into 24 groups of 30 people each, wherein each group included 10 people with bacterial vaginitis, 10 people with trichomonas vaginitis, and 10 people with comprehensive vaginitis. The bath salts prepared in examples 1-8 and the bath salts prepared in comparative examples 1-16 were used for 24 groups of women, respectively. The specific using method comprises the following steps: adding 200ml of hot water into 4g of bath salt, stirring until the bath salt is dissolved, standing until the water temperature is moderate, cleaning private parts for 2-3 minutes, and washing with clear water for 40 days continuously, wherein the detection results are shown in table 4, and the table 4 shows the clinical effect test results of the bath salt prepared in the examples 1-8 and the bath salt prepared in the proportions 1-16.
TABLE 4
As can be seen from the data in Table 4, the bath salts prepared in examples 1 to 8 according to the present invention are effective in preventing the occurrence and recurrence of the private diseases. The bath salts of comparative examples 1-7 containing only a single Chinese medicinal component and the bath salts of comparative examples 8-14 lacking any Chinese medicinal component are much less effective than the bath salts prepared in the present application. The seven traditional Chinese medicine components of the bath salt are mutually matched, and the bath salt has the effects of sterilization, inflammation diminishing and itching relieving after synergistic interaction, can not generate drug resistance after long-term use, has the efficacy of assisting in beautifying private parts, and can effectively prevent the occurrence and recurrence of private diseases.
Test example 4
Removing odor and restoring skin elasticity of private parts
The bath salts prepared in examples 1 to 8 and the bath salts prepared in comparative examples 1 to 16 were evaluated for their effects of deodorizing and restoring the elasticity of the skin in private areas by comparative analysis. 480 healthy female volunteers were collected, but had symptoms of thick private odor and loose private skin, and the samples were used in 20 people per group every day at night. After 30 days, the results of observation are shown in Table 5 for the results of the tests for deodorizing and restoring the elasticity of the skin of private parts for the bath salts prepared in examples 1 to 8 and the bath salts prepared in comparative examples 1 to 16.
TABLE 5
As can be seen from the data in Table 5, the bath salts prepared in examples 1 to 8 according to the present invention are excellent in deodorizing and restoring the elasticity of private skin. The bath salts of comparative examples 1-7 containing only a single Chinese medicinal component and the bath salts of comparative examples 8-14 lacking any Chinese medicinal component are much less effective than the bath salts prepared in the present application. The seven traditional Chinese medicine components of the bath salt are mutually matched, and after synergistic interaction, the bath salt not only has the effects of sterilizing, diminishing inflammation and relieving itching, but also has the effects of removing peculiar smell and recovering the elasticity of private skin, can not generate drug resistance after long-term use, and has the effect of assisting in beautifying private parts.
The applicant states that the present invention is illustrated by the above examples of the private skin cleansing bath salt of the present invention, but the present invention is not limited to the above examples, i.e. it is not meant that the present invention must rely on the above examples to be practiced. It should be understood by those skilled in the art that any modification of the present invention, equivalent substitutions of the raw materials of the product of the present invention, addition of auxiliary components, selection of specific modes, etc., are within the scope and disclosure of the present invention.
Claims (29)
1. The private skin cleaning bath salt is characterized in that the bath salt is prepared from raw materials including salt and a traditional Chinese medicine composition; the mass ratio of the salt to the raw materials for preparing the traditional Chinese medicine composition is (3-8) to 1;
the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-15 parts of radix sophorae flavescentis, 5-15 parts of golden cypress, 5-10 parts of curcuma zedoary, 5-10 parts of honeysuckle, 1-5 parts of fructus cnidii, 1-3 parts of rheum officinale and 1-3 parts of dandelion;
the salt comprises one or more of sea salt, kosher salt, himalayan rock salt, black salt and Persian blue salt.
2. The private skin cleansing bath salt according to claim 1, wherein said bath salt is prepared from raw materials further comprising a surfactant.
3. The private skin cleansing bath salt according to claim 2, wherein the surfactant is present in the bath salt in an amount of 1-10% by weight.
4. The private skin cleansing bath salt according to claim 2, wherein said surfactant is selected from any one of or a combination of at least two of sodium fatty acid, alkyl glycoside, sodium alpha-olefin sulfonate, sodium fatty acid methyl ester sulfonate, or dodecylamine ethyl glycine.
5. The private skin cleansing bath salt of claim 1, wherein said bath salt is prepared from raw materials further comprising a penetration enhancer.
6. The private skin cleansing bath salt according to claim 5, wherein the penetration enhancer is present in the bath salt in an amount of 0.5-2% by weight.
7. The private skin cleansing bath salt according to claim 5, wherein said penetration enhancer is selected from any one or a combination of at least two of borneol, menthol, aromatic oil, azone, or thiaketone.
8. The private skin cleansing bath salt according to claim 1, wherein said bath salt is prepared from raw materials further comprising perfume.
9. The private skin cleansing bath salt according to claim 8, wherein the bath salt comprises 0.1-0.5% by weight of perfume.
10. The private skin cleansing bath salt according to claim 8, wherein the perfume is selected from any one of or a combination of at least two of jasmine extract, vanilla tincture, vanilla balsam, peppermint oil, lavender essential oil, chamomile essential oil, or rose essential oil.
11. The method of preparing a private skin cleansing bath salt according to any of claims 1-10, wherein the method of preparing the bath salt comprises the steps of:
(1) sieving salt: grinding the selected salt, and sieving to obtain fine salt;
(2) traditional Chinese medicine pretreatment: pulverizing and mixing the components of the Chinese medicinal composition, extracting, and concentrating to obtain Chinese medicinal extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding water to prepare paste, concentrating and drying to obtain the private skin cleaning bath salt.
12. The method as claimed in claim 11, wherein the fine salt in step (1) has a particle size of 100-200 mesh.
13. The method as claimed in claim 11, wherein the particle size of the pulverized and mixed Chinese medicinal composition in step (2) is 100-500 mesh.
14. The preparation method according to claim 11, wherein the extraction of step (2) specifically comprises the steps of: adding an extraction solvent into the crushed and mixed traditional Chinese medicine composition, soaking, separating and concentrating to obtain a concentrated solution, thus obtaining the traditional Chinese medicine extract.
15. The method of claim 14, wherein the extraction solvent comprises water and/or ethanol.
16. The preparation method of claim 14, wherein the mass ratio of the extraction solvent to the Chinese medicinal composition is (1-10): 1.
17. The method of claim 14, wherein the soaking time is 1-5 hours.
18. The method of claim 14, wherein the temperature of the soaking is 40-80 ℃.
19. The method of claim 14, wherein the separation is centrifugation.
20. The method according to claim 11, wherein the concentration in step (2) further comprises purification of the herbal extract.
21. The method of claim 20, wherein the purification is performed using a macroporous resin.
22. The method of claim 21, wherein the macroporous resin has a particle size of 20-50 mesh.
23. The method of claim 21, wherein the macroporous resin is selected from any one or a combination of at least two of AB-8, D1300, or D101.
24. The method according to claim 11, wherein the temperature of the cream preparation in the step (3) is 40 to 80 ℃.
25. The method according to claim 11, wherein the drying in step (3) is vacuum drying.
26. The method according to claim 11, wherein the drying temperature in the step (3) is 10 to 30 ℃.
27. The method of claim 11, wherein the bath salt is prepared by the steps of:
(1) sieving salt: grinding the selected salt, and sieving to obtain fine salt;
(2) traditional Chinese medicine pretreatment: extracting and concentrating the components in the traditional Chinese medicine composition to obtain a traditional Chinese medicine extract;
(3) mixing the fine salt and the traditional Chinese medicine extract, adding a surfactant, a penetration enhancer and a spice, uniformly mixing, adding water to prepare paste, concentrating and drying to obtain the private skin cleaning bath salt.
28. The method of claim 11, wherein the bath salt is prepared by the steps of:
(1) sieving salt: grinding and sieving the selected salt to obtain 200-mesh fine salt with the granularity of 100-;
(2) traditional Chinese medicine pretreatment: pulverizing each component in the traditional Chinese medicine composition into 100-500 meshes, adding an extraction solvent into the pulverized and mixed traditional Chinese medicine composition, wherein the mass ratio of the extraction solvent to the traditional Chinese medicine composition is (1-10) to 1, soaking for 1-5h at 40-80 ℃, performing centrifugal separation, and concentrating to obtain a concentrated solution, namely the traditional Chinese medicine extract;
(3) mixing the fine salt and the Chinese medicinal extract, adding surfactant, penetration enhancer and perfume, mixing, adding water at 40-80 deg.C to obtain paste, concentrating, and drying to obtain the private skin cleaning bath salt.
29. Use of a personal cleansing bath salt according to any of claims 1-10, characterized in that the bath salt is used for the preparation of a female personal care product.
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| CN114869812A (en) * | 2021-04-19 | 2022-08-09 | 苏州宝丽洁日化有限公司 | Antibacterial composition and wet toilet paper containing same |
| CN113876688A (en) * | 2021-09-29 | 2022-01-04 | 四川公鼎生物科技有限公司 | Antibacterial maintenance lotion and preparation method thereof |
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