CN110433219A - A kind of compound essence of veterinary oral liquid proposes technique - Google Patents

A kind of compound essence of veterinary oral liquid proposes technique Download PDF

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Publication number
CN110433219A
CN110433219A CN201910734646.5A CN201910734646A CN110433219A CN 110433219 A CN110433219 A CN 110433219A CN 201910734646 A CN201910734646 A CN 201910734646A CN 110433219 A CN110433219 A CN 110433219A
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parts
oral liquid
mixed solution
veterinary oral
raw material
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许恒
印荔
连壮
赵世华
冯多多
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Jiangsu Hebao Pharmaceutical Co Ltd
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Jiangsu Hebao Pharmaceutical Co Ltd
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/76Salicaceae (Willow family), e.g. poplar
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Abstract

The invention discloses a kind of compound essences of veterinary oral liquid to propose technique, processing step is proposed including following compound essence: S1, preparing raw material, veterinary oral liquid includes the raw material of following mass fraction: 30~38 parts of poplar flower, 3.5~4.5 parts of rheum officinale, 3.8~4.8 parts of Cortex Phellodendri, 5.2~6.2 parts of radix scutellariae, 3.2~3.6 parts of Radix Isatidis, 1.8~2.8 parts of dandelion, 3.8~4.2 parts of cellulase, 250~380 parts of deionized water;S2, it extracts for the first time, first the rheum officinale of above-mentioned mass parts and dandelion is put into extractor, are then placed in deionized water, first by water tune pH to 4.5~5.0, after being heated to 90~100 DEG C, extract 20~30min, obtain mixed solution A.The present invention is formed by plurality of Chinese compound, and extraction process is simple, at low cost, can effective preventing cold, be suitble to promote the use of.

Description

A kind of compound essence of veterinary oral liquid proposes technique
Technical field
The present invention relates to the compound essences of veterinary oral liquid to mention answering for technology field more particularly to a kind of veterinary oral liquid Fang Jingti technique.
Background technique
Traditional veterinary oral liquid preparation method is complicated, and ethyl alcohol removal of impurities need to be used for multiple times, and effective component extraction rate is low.With The continuous rise of Chinese medicine price, how more effectively to extract the effective component of Chinese medicine, reduce herb resource waste at For the emphasis of preparation process research.How to guarantee the stability of product simultaneously, shorten process time, reduce process procedure, reduces Technique and energy loss are also preparation research urgent problem.
The antibacterial anti-inflammatory of chemical drugs for animals has been unable to meet production requirement, and only Chinese medicine has natural sex, noresidue, nothing The features such as drug resistance and comprehensively regulating, more and more using the inexorable trend for being modern cultivation development in animal productiong.
Existing poplar flower oral liquid does not have the effect of preventing cold, and preparation process is complicated, at high cost, for this purpose, this hair A kind of bright compound essence for proposing veterinary oral liquid proposes technique
Summary of the invention
The purpose of the present invention is to solve the effects that poplar flower oral liquid in the prior art does not have preventing cold, and make Standby complex process, problem at high cost, and a kind of compound essence of the veterinary oral liquid proposed proposes technique.
To achieve the goals above, present invention employs following technical solutions:
A kind of compound essence of veterinary oral liquid proposes technique, including following compound essence proposes processing step:
S1, prepare raw material, veterinary oral liquid includes the raw material of following mass fraction: 30~38 parts of poplar flower, rheum officinale 3.5~ 4.5 parts, 3.8~4.8 parts of Cortex Phellodendri, 5.2~6.2 parts of radix scutellariae, 3.2~3.6 parts of Radix Isatidis, 1.8~2.8 parts of dandelion, cellulose 3.8~4.2 parts of enzyme, 250~380 parts of deionized water;
S2, it extracts for the first time, first the rheum officinale of above-mentioned mass parts and dandelion is put into extractor, are then placed in deionization Water after being heated to 90~100 DEG C, extracts 20~30min, obtains mixed solution A first by water tune pH to 4.5~5.0;
S3, it extracts for second, by mixed solution A tune pH to 5.0~5.5, after being heated to 80~90 DEG C, then extractor of cooking The middle Cortex Phellodendri that above-mentioned mass parts are added, extracts 20~30min, the radix scutellariae of above-mentioned mass parts is then added, continue extraction 15~ 20min adds the Radix Isatidis of above-mentioned mass parts, continues 20~30min of extraction, obtains mixed solution B;
S4, third time are extracted, and by mixed solution B tune pH to 4.8~5.2, after being heated to 60~70 DEG C, add above-mentioned matter Poplar flower and the cellulase for measuring part, extract 50~60min, obtain mixed solution C;
S5, mixed solution C is filtered, adjusts pH to 5.2~5.5 to get extracting solution D for animals.
Preferably, it in the S2, in entire extraction process, is stirred once every 3~5min, the time of stirring is 2 ~5min.
Preferably, in the S1, prepare raw material, veterinary oral liquid includes the raw material of following mass fraction: 30 parts of poplar flower, 3.5 parts of rheum officinale, 3.8 parts of Cortex Phellodendri, 5.2 parts of radix scutellariae, 3.2 parts of Radix Isatidis, 1.8 parts of dandelion, 3.8 parts of cellulase, deionized water 250 parts.
Preferably, in the S1, prepare raw material, veterinary oral liquid includes the raw material of following mass fraction: 35 parts of poplar flower, 4.0 parts of rheum officinale, 4.3 parts of Cortex Phellodendri, 5.7 parts of radix scutellariae, 3.4 parts of Radix Isatidis, 2.4 parts of dandelion, 4.0 parts of cellulase, deionized water 320 parts.
Preferably, in the S1, prepare raw material, veterinary oral liquid includes the raw material of following mass fraction: 38 parts of poplar flower, 4.5 parts of rheum officinale, 4.8 parts of Cortex Phellodendri, 6.2 parts of radix scutellariae, 3.6 parts of Radix Isatidis, 2.8 parts of dandelion, 4.2 parts of cellulase, deionized water 380 parts.
Preferably, the tune pH lactic acid solution of 20-30% or the sodium hydroxide solution of 20-30%.
Preferably, it in the S2, extracts, the rheum officinale of above-mentioned mass parts and dandelion is put into extractor for the first time first, It is then placed in deionized water, first by water tune pH to 4.8, after being heated to 95 DEG C, 25min is extracted, obtains mixed solution A.
Preferably, in the S3, second of extraction by mixed solution A tune pH to 5.2, after being heated to 85 DEG C, then is cooked and is mentioned The Cortex Phellodendri that above-mentioned mass parts are added in tank is taken, 25min is extracted, the radix scutellariae of above-mentioned mass parts is then added, continues to extract 17min, The Radix Isatidis for adding above-mentioned mass parts continues to extract 25min, obtains mixed solution B.
Preferably, in the S4, third time is extracted, and mixed solution B tune pH to 5.0 is added after being heated to 65 DEG C Poplar flower and the cellulase of mass parts are stated, 55min is extracted, obtains mixed solution C.
Preferably, in the S5, mixed solution C is filtered, adjusts pH to 5.4 to get extracting solution D for animals.
Compared with prior art, the present invention provides a kind of compound essences of veterinary oral liquid to propose technique, has following beneficial Effect:
1, by the addition of poplar flower, the intractable diarrhea that the unknown cause of disease causes poultry, the intestines of unknown cause are eliminated rapidly Tract disease.Such as egg, broiler chicken intractable diarrhea, excrement is thin to be mixed such as starchiness even water sample shape in yellow green or yellow-white sometimes There is a small amount of blood;Piglet yellow scour, dysentery characterized by white mucous stool, transmissible gastroenteritis, in big pig water sample loose stools, perianal villus faecal contamination etc. Illness;
2, alleviate the various stress reactions during the various disease incidences of domestic animal, the laying rate and feed that can significantly improve chicken turn Rate reduces the generation of diarrhoeal diseases, clearing heat and detoxicating, relieving diarrhea with astringents, dampness elimination stop dysentery, strengthening spleen and nourishing stomach;
It 3, can be with preventing cold by Radix Isatidis, radix scutellariae and the addition of dandelion;
4, by repeatedly extracting, essence can be carried out to Chinese medicine to the greatest extent and taken, do not wasted raw material, pass through cellulase Addition, can further extract the Essence of each Chinese medicine, obtained extracting solution component content is more.
And be not directed to part in the device and be the same as those in the prior art or can be realized by using the prior art, the present invention Formed by plurality of Chinese compound, extraction process is simple, at low cost, can effective preventing cold, be suitble to promote the use of.
Detailed description of the invention
Fig. 1 is the flow chart that a kind of compound essence of veterinary oral liquid proposed by the present invention proposes technique.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
Referring to Fig.1, a kind of compound essence of veterinary oral liquid proposes technique, including following compound essence proposes processing step:
S1, prepare raw material, veterinary oral liquid includes the raw material of following mass fraction: 30~38 parts of poplar flower, rheum officinale 3.5~ 4.5 parts, 3.8~4.8 parts of Cortex Phellodendri, 5.2~6.2 parts of radix scutellariae, 3.2~3.6 parts of Radix Isatidis, 1.8~2.8 parts of dandelion, cellulose 3.8~4.2 parts of enzyme, 250~380 parts of deionized water;
S2, it extracts for the first time, first the rheum officinale of above-mentioned mass parts and dandelion is put into extractor, are then placed in deionization Water after being heated to 90~100 DEG C, extracts 20~30min, obtains mixed solution A first by water tune pH to 4.5~5.0;
S3, it extracts for second, by mixed solution A tune pH to 5.0~5.5, after being heated to 80~90 DEG C, then extractor of cooking The middle Cortex Phellodendri that above-mentioned mass parts are added, extracts 20~30min, the radix scutellariae of above-mentioned mass parts is then added, continue extraction 15~ 20min adds the Radix Isatidis of above-mentioned mass parts, continues 20~30min of extraction, obtains mixed solution B;
S4, third time are extracted, and by mixed solution B tune pH to 4.8~5.2, after being heated to 60~70 DEG C, add above-mentioned matter Poplar flower and the cellulase for measuring part, extract 50~60min, obtain mixed solution C;
S5, mixed solution C is filtered, adjusts pH to 5.2~5.5 to get extracting solution D for animals.
Embodiment 1
A kind of compound essence of veterinary oral liquid proposes technique, including following compound essence proposes processing step:
S1, prepare raw material, veterinary oral liquid includes the raw material of following quality: poplar flower 30g, rheum officinale 3.5g, Cortex Phellodendri 3.8g, Radix scutellariae 5.2g, Radix Isatidis 3.2g, dandelion 1.8g, cellulase 3.8g, deionized water 250g;
S2, it extracts for the first time, first the rheum officinale of above-mentioned quality and dandelion is put into extractor, are then placed in deionization Water after being heated to 90 DEG C, extracts 20min, obtains mixed solution A first by water tune pH to 4.5;
S3, it extracts for second, mixed solution A tune pH to 5.0 is added after being heated to 80 DEG C, then in extractor of cooking The Cortex Phellodendri of quality is stated, 20min is extracted, the radix scutellariae of above-mentioned quality is then added, continues to extract 15min, adds above-mentioned quality Radix Isatidis continues to extract 20min, obtains mixed solution B;
S4, third time are extracted, and by mixed solution B tune pH to 4.8, after being heated to 60 DEG C, add the poplar of above-mentioned quality Colored and cellulase extracts 50min, obtains mixed solution C;
S5, mixed solution C is filtered, adjusts pH to 5.2 to get extracting solution D for animals.
Embodiment 2
A kind of compound essence of veterinary oral liquid proposes technique, including following compound essence proposes processing step:
S1, prepare raw material, veterinary oral liquid includes the raw material of following quality: poplar flower 35g, rheum officinale 4.0g, Cortex Phellodendri 4.3g, Radix scutellariae 5.7g, Radix Isatidis 3.4g, dandelion 2.4g, cellulase 4.0g, deionized water 320g;
S2, it extracts for the first time, first the rheum officinale of above-mentioned mass parts and dandelion is put into extractor, are then placed in deionization Water after being heated to 95 DEG C, extracts 25min, obtains mixed solution A first by water tune pH to 4.8;
S3, it extracts for second, mixed solution A tune pH to 5.2 is added after being heated to 85 DEG C, then in extractor of cooking The Cortex Phellodendri of mass parts is stated, 25min is extracted, the radix scutellariae of above-mentioned mass parts is then added, continues to extract 17min, adds above-mentioned matter The Radix Isatidis for measuring part continues to extract 25min, obtains mixed solution B;
S4, third time are extracted, and by mixed solution B tune pH to 5.0, after being heated to 65 DEG C, add the poplar of above-mentioned mass parts Tree is colored and cellulase, extraction 55min obtain mixed solution C;
S5, mixed solution C is filtered, adjusts pH to 5.4 to get extracting solution D for animals.
Embodiment 3
A kind of compound essence of veterinary oral liquid proposes technique, including following compound essence proposes processing step:
S1, prepare raw material, veterinary oral liquid includes the raw material of following quality: poplar flower 38g, rheum officinale 4.5g, Cortex Phellodendri 4.8g, Radix scutellariae 6.2g, Radix Isatidis 3.6g, dandelion 2.8g, cellulase 4.2g, deionized water 380g;
S2, it extracts for the first time, first the rheum officinale of above-mentioned quality and dandelion is put into extractor, are then placed in deionization Water after being heated to 100 DEG C, extracts 20~30min, obtains mixed solution A first by water tune pH to 5.0;
S3, it extracts for second, mixed solution A tune pH to 5.5 is added after being heated to 90 DEG C, then in extractor of cooking The Cortex Phellodendri of quality is stated, 30min is extracted, the radix scutellariae of above-mentioned quality is then added, continues to extract 20min, adds above-mentioned quality Radix Isatidis continues 20~30min of extraction, obtains mixed solution B;
S4, third time are extracted, and by mixed solution B tune pH to 5.2, after being heated to 70 DEG C, add the poplar of above-mentioned quality Colored and cellulase extracts 60min, obtains mixed solution C;
S5, mixed solution C is filtered, adjusts pH to 5.5 to get extracting solution D for animals.
In the present invention, in use, being eliminated rapidly under the intractable that the unknown cause of disease causes poultry by the addition of poplar flower Dysentery, the intestines problem of unknown cause.Such as egg, broiler chicken intractable diarrhea, the thin such as starchiness of excrement even water sample shape, is in yellow green Or yellow-white, it is mixed with a small amount of blood sometimes;Piglet yellow scour, dysentery characterized by white mucous stool, transmissible gastroenteritis, in big pig water sample loose stools, perianal The illnesss such as villus faecal contamination;Alleviate the various stress reactions during the various disease incidences of domestic animal, the production of chicken can be significantly improved Egg rate and feed conversion rate reduce the generation of diarrhoeal diseases, clearing heat and detoxicating, relieving diarrhea with astringents, dampness elimination stop dysentery, strengthening spleen and nourishing stomach;Pass through plate Lan Gen, radix scutellariae and the addition of dandelion, can be with preventing cold;By repeatedly extracting, essence can be carried out to Chinese medicine to the greatest extent It takes, does not waste raw material, by the addition of cellulase, can further extract the Essence of each Chinese medicine, obtained extraction Liquid component content is more.And be not directed to part in the device and be the same as those in the prior art or can be realized by using the prior art, The present invention is formed by plurality of Chinese compound, and extraction process is simple, at low cost, can effective preventing cold, be suitble to promote the use of.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (10)

1. a kind of compound essence of veterinary oral liquid proposes technique, which is characterized in that propose processing step including following compound essence:
S1, prepare raw material, veterinary oral liquid includes the raw material of following mass fraction: 30~38 parts of poplar flower, rheum officinale 3.5~4.5 Part, 3.8~4.8 parts of Cortex Phellodendri, 5.2~6.2 parts of radix scutellariae, 3.2~3.6 parts of Radix Isatidis, 1.8~2.8 parts of dandelion, cellulase 3.8~4.2 parts, 250~380 parts of deionized water;
S2, it extracts for the first time, first the rheum officinale of above-mentioned mass parts and dandelion is put into extractor, are then placed in deionized water, First by water tune pH to 4.5~5.0, after being heated to 90~100 DEG C, 20~30min is extracted, mixed solution A is obtained;
S3, it extracts for second, mixed solution A tune pH to 5.0~5.5 adds after being heated to 80~90 DEG C, then in extractor of cooking Enter the Cortex Phellodendri of above-mentioned mass parts, extract 20~30min, the radix scutellariae of above-mentioned mass parts is then added, continues 15~20min of extraction, The Radix Isatidis for adding above-mentioned mass parts continues 20~30min of extraction, obtains mixed solution B;
S4, third time are extracted, and by mixed solution B tune pH to 4.8~5.2, after being heated to 60~70 DEG C, add above-mentioned mass parts Poplar flower and cellulase, extract 50~60min, obtain mixed solution C;
S5, mixed solution C is filtered, adjusts pH to 5.2~5.5 to get extracting solution D for animals.
2. a kind of compound essence of veterinary oral liquid according to claim 1 proposes technique, which is characterized in that whole in the S2 It in a extraction process, is stirred once every 3~5min, the time of stirring is 2~5min.
3. a kind of compound essence of veterinary oral liquid according to claim 1 proposes technique, which is characterized in that quasi- in the S1 Standby raw material, veterinary oral liquid includes the raw material of following mass fraction: 30 parts of poplar flower, 3.5 parts of rheum officinale, 3.8 parts of Cortex Phellodendri, radix scutellariae 5.2 parts, 3.2 parts of Radix Isatidis, 1.8 parts of dandelion, 3.8 parts of cellulase, 250 parts of deionized water.
4. a kind of compound essence of veterinary oral liquid according to claim 1 proposes technique, which is characterized in that quasi- in the S1 Standby raw material, veterinary oral liquid includes the raw material of following mass fraction: 35 parts of poplar flower, 4.0 parts of rheum officinale, 4.3 parts of Cortex Phellodendri, radix scutellariae 5.7 parts, 3.4 parts of Radix Isatidis, 2.4 parts of dandelion, 4.0 parts of cellulase, 320 parts of deionized water.
5. a kind of compound essence of veterinary oral liquid according to claim 1 proposes technique, which is characterized in that quasi- in the S1 Standby raw material, veterinary oral liquid includes the raw material of following mass fraction: 38 parts of poplar flower, 4.5 parts of rheum officinale, 4.8 parts of Cortex Phellodendri, radix scutellariae 6.2 parts, 3.6 parts of Radix Isatidis, 2.8 parts of dandelion, 4.2 parts of cellulase, 380 parts of deionized water.
6. a kind of compound essence of veterinary oral liquid according to claim 1 proposes technique, which is characterized in that the tune pH is used The lactic acid solution of 20-30% or the sodium hydroxide solution of 20-30%.
7. a kind of compound essence of veterinary oral liquid according to claim 1 proposes technique, which is characterized in that in the S2, the It is primary to extract, first the rheum officinale of above-mentioned mass parts and dandelion are put into extractor, are then placed in deionized water, first by water tune pH To 4.8, after being heated to 95 DEG C, 25min is extracted, mixed solution A is obtained.
8. a kind of compound essence of veterinary oral liquid according to claim 1 proposes technique, which is characterized in that in the S3, the The Huang of above-mentioned mass parts is added in mixed solution A tune pH to 5.2 by second extraction after being heated to 85 DEG C, then in extractor of cooking Cypress extracts 25min, the radix scutellariae of above-mentioned mass parts is then added, and continues to extract 17min, adds the Radix Isatidis of above-mentioned mass parts, Continue to extract 25min, obtains mixed solution B.
9. a kind of compound essence of veterinary oral liquid according to claim 1 proposes technique, which is characterized in that in the S4, the It extracts three times, by mixed solution B tune pH to 5.0, after being heated to 65 DEG C, adds poplar flower and the cellulose of above-mentioned mass parts Enzyme extracts 55min, obtains mixed solution C.
10. a kind of compound essence of veterinary oral liquid according to claim 1 proposes technique, which is characterized in that right in the S5 Mixed solution C filtering, adjusts pH to 5.4 to get extracting solution D for animals.
CN201910734646.5A 2019-08-09 2019-08-09 A kind of compound essence of veterinary oral liquid proposes technique Pending CN110433219A (en)

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Citations (2)

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Application publication date: 20191112