CN110426509A - A kind of detection device - Google Patents
A kind of detection device Download PDFInfo
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- CN110426509A CN110426509A CN201910689892.3A CN201910689892A CN110426509A CN 110426509 A CN110426509 A CN 110426509A CN 201910689892 A CN201910689892 A CN 201910689892A CN 110426509 A CN110426509 A CN 110426509A
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- 238000001514 detection method Methods 0.000 title claims abstract description 80
- 238000007789 sealing Methods 0.000 claims abstract description 44
- 230000008859 change Effects 0.000 claims abstract description 11
- 238000012790 confirmation Methods 0.000 claims description 5
- 239000007788 liquid Substances 0.000 abstract description 51
- 238000012360 testing method Methods 0.000 abstract description 21
- 238000000034 method Methods 0.000 abstract description 6
- 238000010586 diagram Methods 0.000 description 14
- 210000002700 urine Anatomy 0.000 description 11
- 238000003825 pressing Methods 0.000 description 9
- 238000012546 transfer Methods 0.000 description 9
- 239000012530 fluid Substances 0.000 description 8
- 238000005192 partition Methods 0.000 description 8
- 238000007689 inspection Methods 0.000 description 6
- 238000004891 communication Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000002117 illicit drug Substances 0.000 description 4
- 230000003993 interaction Effects 0.000 description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 2
- 239000002360 explosive Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 description 1
- 206010013654 Drug abuse Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 230000003533 narcotic effect Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/52—Containers specially adapted for storing or dispensing a reagent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a kind of detection devices, including the first chamber for collection and for the second chamber of detection, second is intracavitary equipped with detecting element, first chamber is equipped with the opening that can be connected to the second chamber, the opening can be by pressure seal, after sealing, the connection between the first chamber and the second chamber is separated；It after pressure change, can be connected between the first chamber and the second chamber, sample can enter the second chamber from the first chamber.Detection device of the invention can collect the sample for secondary detection while collecting detection sample, simple and quick；Detection device of the invention can quantitatively collect sample, carry out accurate quantitative detection, and testing result is true and reliable, and accuracy is higher；And the application method of detection device of the present invention is simple, and operation is easy；The present invention can also adjust the quality into the liquid sample in the second chamber by the control time, and then can carry out accurate quantitative detection.
Description
Technical field
The present invention relates to detection devices, more particularly to the device that can be detected and be collected.
Background technique
Currently, for detect in sample whether the detection device containing analyte, be largely used to hospital or family
In, these detection devices for being applied to quick diagnosis include one or more detection reagent items, for example early pregnancy detects, drug abuse
Detection etc..The detection device of this quick diagnosis is very convenient, can be at one minute, or at most ten minutes or so are detecting
Testing result is obtained on reagent strip.
Illicit drugs inspection is widely used, be usually used in prohibition of drug department, public security bureau, narcotic house, medical center, country conscription physical examination at
Etc. mechanisms.Illicit drugs inspection wide variety, number is frequent, can be automatically separated the illicit drugs inspection urine cup of remaining sample Yu detected sample
With the huge market demand, after detection is completed, sample in urine cup will be by for illicit drugs inspection urine cup currently on the market
To detection reagent pollution and cannot continue on for second of confirmation detection, such as United States Patent (USP) 7300633 describe as.
The acquisition of big duration set exists in the prior art and is detected on integrated disposable detection device, such as Chinese patent
2008103055231 descriptions, including cup body (being equivalent to collecting chamber), the side of cup body is equipped with the test board (phase containing test paper
When in test chamber), cup body can be connected to the region where test board, such as the 0005th segment description of specification of this document, by
Urine is placed in urine cup by testing staff, and the intercommunicating pore on the liquid outlet and cup body on positioning element control test board at this time is not
Connection, when personnel to be detected detect, testing staff adjusts positioning element, by liquid outlet and intercommunicating pore connection, simultaneously
Cup body is inverted, urine flows into test-strips cavity, autonomous starting reaction.When after reaction, interpretation simultaneously records as a result, will
Urine cup is just set, and the separation of the urine in the urine and urine cup in detection zone is realized.In this manner, urine is controlled
The amount for flowing into detection zone, needs testing staff according to itself experience and work habit to operate, and can not determine into detection
Region carries out running on the test strip the amount of the liquid sample of plate, however, the control of the amount of sample is past during Precision measurement
Have a great impact toward meeting to testing result.
It for these above-mentioned technical problems, therefore needs to make improvements, other approach is provided and solves existing traditional skill
The deficiency of art.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of detection devices, can either carry out the acquisition of liquid sample,
Detection and secondary collection, and can be realized accurate quantitative detection.
The technical proposal adopted by the invention to solve the above technical problems is that:
A kind of detection device, including the first chamber for collection and for the second chamber of detection, the second intracavitary be equipped with is detected
Element, the first chamber are equipped with the opening that can be connected to the second chamber, and the opening can be by pressure seal, after sealing, the first chamber
And the second connection between chamber is separated；It after pressure change, can be connected between the first chamber and the second chamber, sample can be from
One chamber enters the second chamber.
Further, second is intracavitary equipped with sealing element.
Further, sealing element can be in the second intracavitary movement, to change the pressure at the second chamber split shed.
Further, second is intracavitary equipped with elastic element.
Further, when second is intracavitary mobile, elastic element is compressed or is rebounded sealing element.
Further, the detecting element can be in the second intracavitary movement.
Further, the sealing element can be with the movement of detecting element and in the second intracavitary movement.
Further, which further includes linkage element, and it is mobile that the linkage element is able to drive the detecting element.
Further, described second is intracavitary equipped with the channel that can allow for the first intracavitary sample to enter.
Further, which further includes the 4th chamber for collecting secondary-confirmation detection sample, and the 4th chamber can be with the
The connection of one chamber or partition.
Further, which further includes the separating element for being connected to or separating the first chamber and the 4th chamber.
Further, which further includes linkage element, the linkage element can with the separating element link to
So that separating element connection or the first chamber of partition and the 4th chamber.
Further, when the separating element separates first chamber and four chambers, the first chamber can be from the 4th chamber quilt
Separation.
Further, the linkage element includes lid, the cover cap can link when closing the detecting element and/or
The separating element.
Further, there is certain angle between the detecting element and the bottom of the detection device.
The beneficial effects of the present invention are:
(1) detection device of the invention can collect the sample for secondary detection while collecting detection sample, letter
It is single quick；Detection device of the invention can quantitatively collect sample, carry out accurate quantitative detection, and testing result really may be used
It leans on, accuracy is higher；And the application method of detection device of the present invention is simple, and operation is easy.
(2) present invention can be by controlling the length of time that interacts with bolt of arc bump or bolt by downward
Active force length of time, to control quality or volume into the second intracavity liquid sample, so as to reach quantitative
Transfer liquid sample, the purpose of quantitative detection, so that testing result is more true and reliable, accuracy is higher；And it can be with
The quality into the liquid sample in the second chamber is adjusted by the control time.In the time of arc bump and bolt interaction
In the period that section is interior or bolt is by downward active force, it can be completed at the same time race plate, obtain testing result.
Detailed description of the invention
Fig. 1 is the explosive view (wherein, the second chamber is in left side) of apparatus of the present invention.
Fig. 2 is the explosive view that apparatus of the present invention are in another state (wherein, the second chamber is on right side).
Fig. 3 is the structural schematic diagram of the first bottle cap.
Fig. 4 is the structural schematic diagram that the first bottle cap and lid are in discrete state.
The first connector and separating element that Fig. 5 is are in the structural schematic diagram of discrete state.
The structural schematic diagram that the first connector and separating element that Fig. 6 is link together (shows arc bump
Structure).
The structural schematic diagram (structure for showing arc bump) that the lid and separating element that Fig. 7 is link together.
Fig. 8 is the structural schematic diagram of inserted sheet.
Fig. 9 is the structural schematic diagram at the inserted sheet back side.
Figure 10 is the right view of Fig. 8.
Figure 11 is the structural schematic diagram of sealing element.
Figure 12 is the structural schematic diagram (in figure, in order to show the structure in the second bottom of chamber portion, having concealed collet) of cup body.
Figure 13 is the structural schematic diagram after Figure 12 is splitted.
Figure 14 is the structural schematic diagram during cover cap closes cup body.
Figure 15 is the longitudinal sectional view of Figure 14.
Figure 16 is the structural schematic diagram that lid and cup body are in discrete state.
Figure 17 is the longitudinal sectional view (having concealed lid) of Figure 16.
Figure 18 is the longitudinal sectional view during cover cap closes cup body.
Figure 19 be cover cap close cup body during longitudinal sectional view (arc bump pressing bolt, sealing element is no longer
Seal the second chamber).
Figure 20 be cover cap close cup body during longitudinal sectional view (arc bump is rolled over another location, arc
The non-pressing bolt of convex block, sealing element seal the second chamber).
After the completion of Figure 21 is pattern detection, the first bottle cap and lid are in discrete state, while at the 4th chamber and the first chamber
In the structural schematic diagram of discrete state.
Figure 22 is the structural schematic diagram that the 4th cavity is in closed state.
Specific embodiment
A specific embodiment of the invention is described in further details below in conjunction with attached drawing, it is noted that implement
Example is only specifically described of the invention, is not construed as limitation of the invention.
Specific embodiment, referring to attached drawing 1-22.
Such as Fig. 1-2, shown in 18-20, a kind of detection device, including the first chamber 1 for collection and for the second of detection
Chamber, second it is intracavitary be equipped with detecting element, the first chamber 1 is equipped with the opening 4 that can be connected to the second chamber, and described be open 4 can be by
Pressure seal, after sealing, the connection between the first chamber and the second chamber can be separated；After pressure change, the first chamber 1 and the second chamber
Between can be connected to, between the first chamber 1 and the second chamber be connected to after, sample can enter the second chamber from the first chamber 1.One
In a little preferred modes, the second chamber is disposed adjacent with the first chamber 1, and the second chamber is located at the side of the first chamber 1, is convenient for sample in this way
This enters the second chamber from the first chamber 1.In some preferred modes, the first chamber 1 and the second chamber have common wall surface 9, opening 4
On common wall surface 9, enter the second chamber in this way convenient for the liquid sample in the first chamber 1.
As shown in Figs. 1-2, in the present embodiment, detection device includes lid 7 and cup body, and cup body includes the first chamber 1 and second
Chamber, lid 7, which can cover, closes the first chamber 1, and lid 7 is connected through a screw thread with the first chamber 1, in other embodiments, lid 7 and first
Chamber 1 is also possible to clamping connection or is attached using other connection types；Second chamber is adjacent with the first chamber 1, the second chamber
Positioned at the side of the first chamber 1, second it is intracavitary be equipped with detecting element, can be connected to or be closed between the first chamber 1, the second chamber,
When being connected between the first chamber 1 and the second chamber, liquid sample may be implemented by the first chamber 1 and enter the second chamber；As Figure 17-20 institute
Show, the first chamber 1 is equipped with the opening 4 that can be connected to the second chamber, this opening 4 can be by pressure seal, such as gas pressure；When
The pressure at left and right sides of at 4 that is open is equal or opening 4 at the gas pressure of the second chamber be greater than the liquid at opening 4 in first chamber 1
When body pressure, though hydraulically full sample in the first chamber 1, and the height of liquid sample is higher than opening 4, the liquid in the first chamber 1
Body sample will not enter in the second chamber from this opening 4, be closed, separate, no between the first chamber 1 and the second chamber at this time
The transfer of liquid sample can occur；The gas pressure of second chamber is less than the fluid pressure at opening 4 in first chamber 1 at opening 4
When, be connected between the first chamber 1 and the second chamber, between the first chamber 1 and the second chamber be connected to after, sample can from the first chamber 1 into
Enter the transfer that liquid sample is realized to the second chamber.
In some preferred modes, as shown in Figs. 1-2, the second chamber includes the second cavity 2 and collet 20, and collet 20 can be with
Receive the liquid sample that the first chamber 1 is transferred to the second chamber, in the present embodiment, collet 20 is connected with the second cavity 2 by welding
It connects, in other preferred modes, collet 20 can also be attached by other means with the second cavity 2, for example, bonding
Deng the second cavity 2 is fixedly connected as after an entirety with collet 20, and there is no the phenomenon of leakage, in some preferred modes
In, the second cavity 2 is obliquely installed, and collet 20 is also obliquely installed, and collet 20 is consistent with the inclined angle of the second cavity 2, still, bottom
The bottom surface of support 20 is horizontal plane, and collet 20 can be positioned horizontally on horizontal plane, so that device is more stable, is conducive to
The progress of detection；In some preferred modes, the angle of the second cavity 2 and horizontal plane is greater than 0οLess than 90ο。
In some preferred modes, as shown in Figs. 1-2, second is intracavitary equipped with inserted sheet 21, as seen in figs. 8-10, inserted sheet 21
Including plate 211, the first support chip 212, the second support chip 213, bolt 23, elastic element and pillar 214, the first support chip
212 are fixedly connected with plate 211 respectively with the second support chip 213, and bolt 23 is fixedly connected with the first support chip 212, pillar 214
It is fixedly connected on the bottom middle position of the second support chip 212；Elastic element is fixedly connected with the second support chip, elastic element set
It is located at pillar periphery.In some preferred modes, elastic element can be spring 72, spring 72 can compress or automatically
Rebound, in some preferred modes, as seen in figs. 8-10, spring 72 is fixedly connected on 212 bottom of the first support chip, spring 72
It is set in 214 periphery of pillar, and the compressed length of spring 72 is greater than the length of pillar 214, pillar 214, which can be avoided, is pressing
In compression process, the distortion offset of spring 72, and also pillar 214 will not influence spring 72 and be compressed.
In some preferred modes, as seen in figs. 8-10, bolt 23 is located at the medium position of the first support chip 212；In
In some preferred modes, bolt 23 includes the first cylindrical body and the second cylindrical body, and the second cylindrical body and the first support chip 212 are solid
Fixed connection, the first cylindrical body and the second cylindrical body are fixedly connected, and the first cylindrical body is located at the second cylindrical body top, the first cylindrical body
Cross-sectional diameter be greater than the second cylindrical body cross-sectional diameter；In some preferred modes, detecting element can be placed
On plate 211；In some preferred modes, as seen in figs. 8-10, the first support chip 212, the second support chip 213 respectively with
Plate 211 is vertical, and the first support chip 212 is connected to the upper end of plate 211, and the second support chip 213 is located at 211 lower end of plate,
But not instead of in end position, position above end position can reserve the space for placing elastic element in this way,
And can be too far apart from collet to avoid detecting element, if detecting element is too far apart from collet 20, it is unfavorable for detection in this way
It carries out.
In some preferred modes, such as Figure 15, shown in 17-20, plate 211 is in the lateral wall of the second cavity 2
Wall surface setting, the tilt angle of plate 211 is consistent with the tilt angle of the second cavity 2, in some preferred modes, such as Fig. 1
Shown, the second chamber upper surface is equipped with jack 22, and bolt 23 is inserted into jack 22, and stretches out jack 22, exposes 23 head of bolt；
Bolt 23 is inserted into jack 22, and inserted sheet 21 is installed in the second intracavitary portion, and in some preferred modes, the second intracavitary be equipped with is sealed
Element, such as Fig. 1-2, shown in 10；Sealing element 71 can cover on the second cylindrical body of bolt 23, and sealing element 71 is located at second
Intracavitary portion, sealing element 71 can seal the second chamber so that the second chamber is isolated from the outside, do not carried out with the external world gas or other
The exchange of substance；When pressing down on bolt 23, inserted sheet 21, sealing element 71 can second it is intracavitary move down, spring
72 are compressed, and the second chamber is in communication with the outside at this time, and the second chamber can carry out gas exchanges, the second intracavitary gas pressure with the external world
Change, specifically, compared with the second chamber is in closed state, the second intracavitary pressure reduces at this time, second chamber at opening 4
When gas pressure is less than the fluid pressure at opening 4 in first chamber 1, the first chamber 1 is connected to the second chamber, the first chamber 1 and second
After chamber connection, sample can enter the second chamber from the first chamber 1, realize the transfer of liquid sample；It is inserted when no longer pressing down on
When pin 23, the meeting automatic rebounding of spring 72, the second support chip 213 will receive upward thrust, and inserted sheet 21, sealing element 71 can
Second it is intracavitary move up, finally, sealing element 71 moves to the top of the second chamber, and sealing element 71 can seal second
Chamber does not carry out exchanging for gas or other substances with extraneous so that the second chamber is isolated from the outside；Liquid-like in first chamber 1
This can be no longer flow into the second chamber at leisure, and the gas pressure in the second chamber will change, specifically, compared with before, at this time
Two intracavitary gas pressures will will increase, and the gas pressure of second chamber is more than or equal to the first chamber 1 at opening 4 at opening 4
In fluid pressure when, the connection between the first chamber 1 and the second chamber is separated, not can be carried out between the two liquid sample turn
It moves.
In some preferred modes, as shown in figure 8, the side wall of plate 211 is placed equipped at least one detecting element
Area 24, for placing detecting element；In some preferred modes, it is identical that multiple detecting element rest areas 24 can place detection
Or the detecting element of different material, it may be implemented to detect one or more kinds of substances simultaneously；It is more in some preferred modes
Partition arm 25 is equipped between a detecting element rest area 24, each detecting element is spaced, is independent of each other；Some preferred
In mode, detecting element rest area 24 is equipped with convex block, and convex block can make detecting element be in fixed position with fixed test element
It sets, guarantees going on smoothly for detection, so that testing result is more accurate, reliable, when the setting of convex block can be to avoid detection, detection
Situations such as element is shifted, fallen down appearance, in some preferred modes, convex block includes the first convex block 26 and the second convex block 27, the
One convex block 26 and the second convex block 27 cooperate, so that keep detecting element more stable.In some preferred modes, such as
Shown in Fig. 8,24 lower part of detecting element rest area is additionally provided with flow-guiding channel 28, and flow-guiding channel 28 can guide liquid sample contact inspection
Element is surveyed, avoids liquid sample from contacting in large quantities with detecting element, influences the accuracy of testing result.In some preferred modes
In, after detecting element is placed into detecting element rest area 24, detecting element is parallel to the lateral wall of the second cavity 2, detection
Element is consistent with the inclined angle of the second cavity 2, then, it is formed centainly between detecting element and the bottom of the detection device
Angle；With detecting element perpendicular to horizontal plane setting compared with, detecting element is in heeling condition, enable liquid sample more
It is rapidly introduced into detecting element, and is rapidly completed on detecting element and runs plate detection.In some preferred modes, the detection
Element can be with the movement of plate 211 and in the second intracavitary movement.In some preferred modes, 71 energy of sealing element
Enough with the movement of detecting element in the second intracavitary movement.
In some preferred modes, which further includes linkage element, and the linkage element is able to drive the detection
Element is mobile.In some preferred modes, the movement of detecting element is realized under external force, in some preferred sides
In formula, linkage element can link with the other component of detection device, for example linkage element can link with inserted sheet 21, inserted sheet 21
Under the action of linkage element, moved, thus drive detecting element mobile, in some preferred modes, linkage element
It can be the other component in detection device, such as lid 7；As illustrated in figs. 5-7, in the present embodiment, linkage element is lid 7,
The periphery of lid 7 is equipped with one section of arc bump 73, and arc bump 73 protrudes from lid 7, when the rotation lid of lid 7 closes the first chamber
When 1, arc bump 73 is at first close to the first chamber 1；Specifically, rotate lid 7, move down lid 7, make arc bump 73 with
Bolt 23 contact, continue rotate lid 7, arc bump 73 will pressing bolt 23, give bolt 23 1 downward active forces, insert
Pin 23 is under pressure, and entire inserted sheet 21 will move down, and sealing element 71, detecting element move down, and spring 72 is compressed, close
Envelope element 71 no longer seal the second chamber, the second chamber is in communication with the outside at this time, the second chamber can with the external world carry out gas exchanges, second
Intracavitary pressure change, compared with the second chamber is in closed state, the second intracavitary pressure reduces at this time, second at opening 4
When the gas pressure of chamber is less than the fluid pressure at opening 4 in first chamber 1, it is connected between the first chamber 1 and the second chamber, the first chamber
After 1 is connected to the second chamber, sample can enter the second chamber from the first chamber 1, realize the transfer of liquid sample.Continue rotation lid
Body 7, arc bump 73 are transferred to another location, and as shown in figure 20, at this position, arc bump 73 is no longer contacted with bolt 23,
Bolt 23 is no longer influenced by downward active force, and the automatic rebounding of the meeting of spring 72 at this time, the second support chip 213 will receive upward push away
Power, inserted sheet 21, sealing element 71 can second it is intracavitary move up, finally, bolt 23 moves to initial position just no longer
Movement, and bolt 23 is not also contacted with lid 7 or bolt 23 is contacted with lid 7, but do not interact between the two
Power, at this point, sealing element 71 moves to the top of the second chamber, sealing element 71 can seal the second chamber so that the second chamber with
External world's isolation does not carry out exchanging for gas or other substances with extraneous；Liquid sample in first chamber 1 can no longer flow at leisure
Entering the second chamber, the gas pressure in the second chamber will change, specifically, and compared with the second chamber is in communication with the outside, at this time second
Intracavitary gas pressure will will increase, and the gas pressure of second chamber is more than or equal at opening 4 in first chamber 1 at opening 4
Fluid pressure when, the connection between the first chamber 1 and the second chamber is separated, and not can be carried out the transfer of liquid sample between the two.
In summary, in the period that arc bump 73 and bolt 23 interact or bolt 23 is by downward effect
In the period of power, it is connected between the first chamber 1 and the second chamber, the liquid sample in the first chamber 1 is able to enter to the second chamber,
Therefore, length of time of the length of time or bolt 23 that arc bump 73 and bolt 23 interact by downward active force
Determine that liquid sample enters the quality of the second chamber in the first chamber 1, it is possible to pass through control arc bump 73 and 23 phase of bolt
Length of time of the length of time or bolt 23 of interaction by downward active force, to control into the second intracavity liquid sample
This quality or volume, so as to reach quantitative transfer liquid sample, the purpose of quantitative detection, so that testing result
It is more true and reliable, accuracy is higher；And the matter into the liquid sample in the second chamber can be adjusted by the control time
Amount.Within the period that arc bump 73 and bolt 23 interact or period of the bolt 23 by downward active force
It is interior, it can be completed at the same time race plate, obtain testing result.
In some preferred modes, such as Figure 13, shown in 15,17-20, the first chamber 1 and the second chamber have common wall surface
9, in some preferred modes, the first support chip 212 can slide on common wall surface 9, can set on this wall surface 9
A resigning breach 8 is set, as shown in Figure 13,15, when the second support chip 213 is located at resigning breach 8, is deposited on the second support chip 213
The liquid sample of storage will flow into the second bottom of chamber portion.In some preferred modes, this common wall surface 9 has a degree of
Inclination, the angle between arm face 9 and horizontal plane is greater than 0οLess than 90ο.In some preferred modes, this common wall surface 9
Tilt angle it is consistent with the inclined angle of the second cavity 2, in some preferred modes, the oral area of the second support chip 213 to
Under, it is flowed out convenient for liquid sample.
Further, the detection device further include for collect secondary-confirmation detection sample the 4th chamber 10, as Fig. 1-2,
Shown in 14-22, the 4th chamber 10 can be connected to or separate with the first chamber 1, in some preferred modes, the 4th chamber 10 and the first chamber
1 removable combination, the 4th chamber 10 can be connected or are threadedly coupled by clamping with the first chamber 1, in other preferred sides
In formula, the 4th chamber 10 can also be connect by other means with the first chamber 1；In some preferred modes, such as Figure 12-13 institute
Show, the first chamber 1 has the first interface channel 31, and the first chamber 1 is connect by the first interface channel 31 with the 4th chamber 10, the first connection
Channel 31 protrudes from the bottom surface of the first chamber 1, and the first interface channel 31 is columnar channel；As shown in figure 21, the 4th chamber 10 has
Have the second interface channel 32 protruding upward, the second interface channel 32 is also columnar channel, the second interface channel 32 it is straight
Diameter is greater than the diameter of the first interface channel 31, then, the second interface channel 32 can cover in 31 outside of the first interface channel, in this way
Enable liquid sample in the first interface channel 31 completely into the second interface channel 32, and then flow into the 4th chamber, no
Liquid sample can be made to leak out, flowed in addition to the second interface channel 32 elsewhere；As shown in figure 17, the first interface channel 31
It is connect with the second interface channel 32, at this point, being in connected state between the 4th chamber 10 and the first chamber 1；If logical in the first connection
A plug or other interruptions are filled in road 31, then, the 4th chamber 10 and the first chamber 1 are just separated.
Further, as shown in Figs. 1-2, which further includes for being connected to or separating the first chamber 1 and the 4th chamber 10
Separating element 80, in some preferred modes, as shown in figure 5, separating element 80 includes the second connector 61 and head, the
Two connectors 61 and head are integrally formed, in some preferred modes, as shown in figure 5, the second connector of separating element 80
61 can be connected and fixed with the first connector 33, and in some preferred modes, the first connector 33 is fixedly connected with lid 7,
It can be integrated molding, in some preferred modes, the first connector 33 is cylindrical shape, and the first connector 33 is far from lid 7
One end be equipped with cylinder opening, in some preferred modes, the second connector 61 is also cylindrical shape, the second connector 61 and the
A connection piece 33 connects, and can be attached using clamping connection or threaded connection or other connection types, such as Fig. 8 institute
Show, in the present embodiment, the second connector 61 be can be inserted in the cylinder opening of the first connector 33, realize connection.
In some preferred modes, as shown in figure 5, the head of separating element 80 has a tip 35, separating element
80 head is able to enter the first interface channel 31, and then can separate the first chamber 1 and the 4th chamber 10, when by separating element 80 from
It is extracted in first interface channel 31, the first chamber 1 can be connected to the 4th chamber 10.In some preferred modes, such as Fig. 5-7 institute
Show, the head of separating element 80 is equipped with the first protrusion 36 and the second protrusion 361, in some preferred modes, the first protrusion 36
It is arranged in parallel with the second protrusion 361, the first raised 36 and second protrusion 361 is arranged at the periphery on 80 head of separating element, In
In some preferred modes, sealing ring is set between the first protrusion 36 and the second protrusion 361, the first protrusion 36 can prevent close
Seal moves up, and the second protrusion 361 can prevent sealing ring from moving down；In some preferred modes, sealing ring can for one or
Person is multiple, and sealing ring can play the role of sealing, can thoroughly separate the first chamber 1 and the 4th chamber 10, avoid liquid sample from
It is flowed out in connection gap.
In some preferred modes, such as Fig. 5-7, shown in 18-20, the head of separating element 80 sets that there are two the second apertures
37, two the second apertures 37 are oppositely arranged, and can be connected between the two, and in some preferred modes, the second aperture 37 is located at
The lower section of sealing ring 36, the top position at tip 35；In some preferred modes, as shown in figure 5, the head of separating element 80
With cavity, two the second apertures 37 can be connected to cavity, and liquid sample can enter cavity, this cavity from the second aperture 37
The liquid sample of certain volume can be kept in, in this way, if being already filled with liquid sample in the 4th chamber 10, and separating element 80 exists
Under the linkage of linkage element, separating element 80 is constantly moved down, and when constantly entering four chambers 10, separating element 80 will will receive resistance
Power, at this point, the liquid sample in the 4th chamber 10 can enter cavity, the resistance for being subject to separating element 80 by the second aperture 37
Reduce, does not influence separating element 80 and go successively to the 4th chamber 10, when separating element 80 is completely into the 4th chamber 10,36 energy of sealing ring
The connection of the first chamber 1 and the 4th chamber 10 of enough partitions completely, at this point it is possible to which the 4th chamber 10 is separated from the first chamber 1.
Further, the linkage element can with the separating element 80 link so that separating element 80 be connected to or
Separate the first chamber 1 and the 4th chamber 10；As Figure 4-Figure 6, in the present embodiment, linkage element is lid 7, the first connector 33 and lid
Body 7 is fixedly connected, and separating element 80 is connected and fixed with the first connector 33, and therefore, lid 7 is mobile, and separating element 80 will be with
Movement, when constantly rotating, tightening lid 7, separating element 80 will be moved down constantly, until enter the first interface channel 31,
As shown in figure 20, at this point, the first chamber 1 and the 4th chamber 10 are in partition state, when constantly rotating, unscrewing lid 7, separating element
80 will constantly move up, and separating element 80 can be detached from the first interface channel 31, and the first chamber 1 and the 4th chamber 10 can be made to be in
Connected state.In some preferred modes, separating element 80 can be linked to be connected to or separate first by linkage element
Chamber 1 and the 4th chamber 10.In some preferred modes, linkage element can link separating element 80 and detecting element simultaneously；This
In embodiment, linkage element is lid 7, and separating element 80 can be moved with the movement of lid 7；Detecting element is located at inserted sheet 21
On, the bolt 23 of inserted sheet 21 is inserted into jack 22, and stretches out jack 22, and lid 7 is located at the top of jack 22, when continuous rotation, twists
When tight lid 7, separating element 80 will be moved down constantly, moreover, arc bump 73 will be moved down constantly, originally, arc bump 73
Contacted with bolt 23, continue rotate lid 7, arc bump 73 will pressing bolt 23, give bolt 23 1 downward active forces,
Bolt 23 is under pressure, and entire inserted sheet 21 will move down, and sealing element 71, detecting element move down, and spring 72 is compressed,
Separating element 80 and detecting element so linkage element can link simultaneously.
Further, when the separating element 80 separates first chamber 1 and four chambers 10, the first chamber 1 can be from
Four chambers 10 are separated, and in some preferred modes, the 4th chamber 10 can be separated from the first chamber 1, as shown in figure 20, partition
Element 80 has separated the first chamber 1 and the 4th chamber 10, at this point it is possible to which the 4th chamber is downwardly drawn out, realizes the 4th chamber 10 and the first chamber 1
Separation.In some preferred modes, the closure member of the 4th chamber 10 can also be set, when the 4th chamber 10 and the first chamber 1 divide
From later, the 4th chamber 10 can be closed, and become a closed individual cavity, so that storage is used for the liquid-like of secondary detection
This, as shown in fig. 21-22, closure member is the first bottle cap 12, and the first bottle cap 12, which can cover, closes the 4th chamber 10, in the first bottle cap 12
Portion is equipped with internal screw thread, and 32 outer wall of the second interface channel of the 4th chamber 10 is equipped with external screw thread, and internal screw thread and external screw thread cooperate, can
To realize that the connection cover of the first bottle cap 12 and the 4th chamber 10 is closed, it can protect the liquid sample stored in the 4th chamber 10 in this way, make
Obtaining the liquid sample stored in the 4th chamber 10 will not leak out or be destroyed.
In some preferred modes, as shown in figure 4, the first bottle cap 12 can be fixed on lid 7, table on lid 7
Face is equipped with pit 38, and 38 medium position of pit is provided with pillar 39, be inside pillar 39 it is hollow, 39 upper end of pillar has first
Aperture 43, in some preferred modes, as shown in figure 3, being equipped with first cooperated with the first aperture 43 inside the first bottle cap 12
The first aperture 43 can be inserted in cylinder 40, the first cylinder 40, realizes the combination of the first bottle cap 12 and lid 7；Some preferred
In mode, as shown in figure 3, being additionally provided with circular side wall 42 inside the first bottle cap 12, circular side wall 42 is centered around the first cylinder 40
Periphery, as shown in figure 4,39 lateral wall of pillar is equipped with convex rib 41, circular side wall 42 can cooperate with convex rib 41, fastening first
The combination of bottle cap 12 and lid 7；In some preferred modes, convex rib 41 can be a plurality of, in some preferred modes,
A plurality of convex rib 41 is uniformly arranged on the lateral wall of pillar 39, and the setting of convex rib 41 can be used to fix the first bottle cap 12, when
When needing, the first bottle cap 12 can be extracted, be allowed to be detached from lid 7, the first bottle cap 12 is covered the second connection in the 4th chamber 10
On channel 32, the 4th chamber 10 is closed by realization.
Further, the linkage element includes lid 7, and in some preferred modes, lid is equipped with arrow, according to
Direction shown in arrow rotates, and can screw lid 7, and the constantly lid of lid 7 is made to close the first chamber；It is described in some preferred modes
Can link the detecting element and/or the separating element 80 when the lid conjunction of lid 7；The lid of lid 7 closes the process of the first chamber 1,
The process of lid 7 is constantly rotated, tightens, lid 7 constantly moves down, and separating element 80 can be moved with the movement of lid 7；
Detecting element is located on inserted sheet 21, and the bolt 23 of inserted sheet 21 is inserted into jack 22, and stretches out jack 22, and lid 7 is located at jack 22
Top, when constantly rotating, tightening lid 7, separating element 80 will be moved down constantly, moreover, arc bump 73 will constantly under
It moves, originally, arc bump 73 is contacted with bolt 23, but between the two without interaction force, is continued to rotate, is tightened lid 7, arc
Shape convex block 73 will pressing bolt 23, give bolt 23 1 downward active forces, bolt 23 is under pressure, and entire inserted sheet 21 will be to
Lower movement, sealing element 71, detecting element move down, and spring 72 is compressed, the inspection so lid of lid 7 can link when closing
Survey element and/or the separating element 80.In some preferred modes, it can close up with the first chamber downwards when the lid of lid 7 closes, cover
Body 7 can push inserted sheet 21 while moving down, and inserted sheet 21 can be in the second intracavitary movement, to make detecting element the
Two intracavitary movements.
In some preferred modes, cup body further includes supporting side walls 51, and as shown in Figs. 1-2, supporting side walls 51 are arc
Side wall, supporting side walls 51 are fixedly connected with the side wall of the first chamber 1, and in some preferred modes, supporting side walls 51 are without complete
Surround the surrounding of the 4th chamber 10, but leaving certain gaps uncovered by the economic plan, the 4th chamber 10 is installed or dismantled in this way convenient for user；Some preferred
Mode in, 51 bottom of supporting side walls be it is horizontal, supporting side walls 51 are horizontally arranged in the horizontal plane, are made so whole
A device can be placed steadily, be readily transported or detect, and in some preferred modes, the setting of supporting side walls 51 is with second
The opposite position of chamber, can be better balanced whole device in this way, place device more steady.
It the present invention also provides the application method of the detection device, is described presently in connection with attached drawing 1-22, including following
Step:
Firstly, (1) opens lid 7, liquid sample is added into the first chamber 1, as shown in figs. 16-17, the first chamber 1 and
The connection of four chambers, liquid sample can be flowed into the 4th chamber 10, the liquid-like in the 4th chamber 10 by the first interface channel 31 of the first chamber 1
This, is continuously increased, after the liquid sample in the 4th chamber 10 is filled, liquid sample can store in the first chamber 1, liquid sample
Height will be higher than the height of opening position and expose 23 head of bolt, sealing at this point, bolt 23 is inserted in jack 22
71 sets of element on bolt 23, sealing element 71 is located at the second intracavitary portion, and sealing element 71 seals the second chamber, so that the second chamber
It is isolated from the outside；Liquid sample in first chamber 1 will not enter the second chambers by opening 4 because at opening 4 second chamber gas
Pressure is more than or equal to the fluid pressure at opening 4 in first chamber 1, is closed between the first chamber 1 and the second chamber, between the two
The transfer of liquid sample is not can be carried out；
(2) rotate lid 7, by lid 7 to lower cover close the first chamber, as depicted in figs. 18-19, originally, arc bump 73 and insert
Pin 23 contacts；Continue to rotate lid 7, as shown in figure 19, arc bump 73 will pressing bolt 23, it is downward to bolt 23 1
Active force, bolt 23 are under pressure, and entire inserted sheet 21 will move down, and sealing element 71, detecting element move down, spring 72
It is compressed, sealing element 71 no longer seals the second chamber, and the second chamber is in communication with the outside at this time, the second intracavitary pressure change, specifically
Ground, compared with the second chamber is in closed state, the second intracavitary pressure reduces at this time, the gas pressure of second chamber at opening 4
When less than fluid pressure at opening 4 in first chamber 1, be connected between the first chamber 1 and the second chamber, the first chamber 1 and the second chamber it
Between be connected to after, sample can enter the second chamber from the first chamber 1, meanwhile, the detection of liquid sample can be carried out；
Continuing to rotate lid 7, arc bump 73 is transferred to another location, as shown in figure 20, and at this position, arc bump 73
It is no longer contacted with bolt 23, bolt 23 is no longer influenced by downward active force, the automatic rebounding of the meeting of spring 72 at this time, the second support chip
213 will receive upward thrust, inserted sheet 21, sealing element 71 can second it is intracavitary move up, finally, bolt 23 moves
Just no longer moved to initial position, at this point, and bolt 23 is not contacted with lid 7 or bolt 23 is contacted with lid 7, but two
There is no interaction force between person, sealing element 71 moves to the top of the second chamber, and sealing element 71 can seal the second chamber,
So that the second chamber is isolated from the outside, exchanging for gas or other substances is not carried out with extraneous；Liquid sample meeting in first chamber 1
It is no longer flow into the second chamber at leisure, the gas pressure in the second chamber will change, specifically, compared with the second chamber is in communication with the outside
Compared with the second intracavitary gas pressure will will increase at this time, and the gas pressure of second chamber is more than or equal to opening 4 at opening 4
When locating the fluid pressure in the first chamber 1, the first chamber 1 and the second chamber are closed, and not can be carried out the transfer of liquid sample between the two；
Lid 7 is rotated, during lid 7 is closed cup body to lower cover, separating element 80 constantly enters the 4th chamber, by the first chamber 1 and the
The partition of four chambers 10, and then can be by a chamber and the 4th partition completely of chamber 10；
(3) after detection is completed, by observing the lateral surface of the second chamber, i.e. readable because cup body be arranged to it is transparent,
Also testing result is conveniently photographed to record；As illustrated in figs 20-22, due to the first chamber 1 and the 4th chamber 10 completely by separating element 80 every
It is disconnected, the first bottle cap 12 and the 4th chamber 10 can be removed at this time, and the first bottle cap 12 is screwed and is covered on the 4th chamber 10, the 4th chamber 10
Liquid can be used for secondary-confirmation detection.
Claims (14)
1. a kind of detection device, characterized in that including the first chamber for collection and for the second chamber of detection, second intracavitary is set
Have a detecting element, the first chamber is equipped with the opening that can be connected to the second chamber, the opening can by pressure seal, after sealing,
Connection between first chamber and the second chamber is separated；After pressure change, it can be connected between the first chamber and the second chamber, sample energy
It is enough to enter the second chamber from the first chamber.
2. a kind of detection device according to claim 1, characterized in that second is intracavitary equipped with sealing element.
3. a kind of detection device according to claim 2, characterized in that sealing element can be in the second intracavitary movement.
4. a kind of detection device according to claim 2, characterized in that second is intracavitary equipped with elastic element.
5. a kind of detection device according to claim 4, characterized in that sealing element is when second is intracavitary mobile, elasticity
Element is compressed or is rebounded.
6. a kind of detection device according to claim 1, characterized in that the detecting element can be in the second intracavitary shifting
It is dynamic.
7. a kind of detection device according to claim 2, characterized in that the sealing element can be with the shifting of detecting element
It is dynamic and in the second intracavitary movement.
8. a kind of detection device according to claim 1, characterized in that it further include linkage element, the linkage element energy
Enough drive the detecting element mobile.
9. a kind of detection device according to claim 1, characterized in that further include for collecting secondary-confirmation detection sample
The 4th chamber, the 4th chamber can be connected to or separate with the first chamber.
10. a kind of detection device according to claim 9, characterized in that further include for be connected to or separate the first chamber and
The separating element of 4th chamber.
11. a kind of detection device according to claim 10, characterized in that it further include linkage element, the linkage element
It can link with the separating element so that separating element is connected to or separates the first chamber and the 4th chamber.
12. a kind of detection device according to claim 11, characterized in that when the separating element separates first chamber
When with four chambers, the first chamber can be separated from the 4th chamber.
13. a kind of detection device according to claim 8 or 11, characterized in that the linkage element includes lid, described
Can link the detecting element and/or the separating element when cover cap conjunction.
14. a kind of detection device according to claim 1, characterized in that the detecting element and the detection device
There is certain angle between bottom.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910689892.3A CN110426509A (en) | 2019-07-29 | 2019-07-29 | A kind of detection device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910689892.3A CN110426509A (en) | 2019-07-29 | 2019-07-29 | A kind of detection device |
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| CN110426509A true CN110426509A (en) | 2019-11-08 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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