CN110279775A - A kind of Chinese medicine composition of phalacrosis prevention and hair generation and preparation method thereof - Google Patents

A kind of Chinese medicine composition of phalacrosis prevention and hair generation and preparation method thereof Download PDF

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CN110279775A
CN110279775A CN201910601599.7A CN201910601599A CN110279775A CN 110279775 A CN110279775 A CN 110279775A CN 201910601599 A CN201910601599 A CN 201910601599A CN 110279775 A CN110279775 A CN 110279775A
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parts
hair
chinese medicine
eclipta
medicine composition
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玄振玉
朱恩圆
陈艳艳
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Shanghai Traditional Chinese Medicine Biotechnology Co Ltd
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Shanghai Traditional Chinese Medicine Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth

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Abstract

The present invention relates to Chinese medicine compositions of a kind of phalacrosis prevention and hair generation and preparation method thereof, it is made of 8 kinds of cacumen biotae, mulberry leaf, eclipta, the fleece-flower root, pine needle, fructus viticis, Radix Angelicae Sinensis, Rhizoma Chuanxiong medicinal materials, specific formula and method are detailed in specification, its advantage is that multicomponent combination, preparation process are easy using the entirety of Chinese medicine, balance theory as foundation, it can thoroughly improve scalp function, nourish anticreep, promote hair growth simultaneously, thus enable people to preferably keep the health of scalp, quality of making the life better.

Description

A kind of Chinese medicine composition of phalacrosis prevention and hair generation and preparation method thereof
Technical field
The present invention relates to Chinese medicines, and in particular to Chinese medicine composition and its preparation side for the phalacrosis prevention and hair generation of the crowd of alopecia Method.
Background technique
The hair of normal person constantly carries out metabolism, falls off from nature is grown into, generally 3~4 years.As long as Human normal carries out metabolic activity, hair just constantly growth, to keep the peculiar looks of the mankind.Due to the speed of growth and hair of hair Educating speed is not equity, and also therefore existing hair tonic also has alopecia.Under normal circumstances, hair tonic carries out in natural conditions, Alopecia is also unconsciously carrying out.From table it is upper from, hair like without big variation, but meticulous inspection it finds that, it is such as interior Dirty ill, trichomadesis can be speeded, or the situations such as show and be unevenly distributed, is sparse.
Alopecia this problem, either Chinese medicine and doctor trained in Western medicine have correlation method to carry out therapeutic intervention.Western medical treatment is main For oral administration and external application, endo-medicine is divided to be adjusted primarily with respect to the hormone of human body, although so many medicines for oral administration have hair Certain benefit, but also more or less influence the inherent secretion of people.And doctor trained in Western medicine external drug, mainly improvement hair follicle, or Person is the nutrition and blood supply for improving scalp.
Chinese medicine thinks although hair is to belong to hair, but have close pass with taste, liver, kidney on the crown of human body System.Blood stored in the liver, liver blood is abundant, and hair can have sufficient blood supply;The spleen has the function to transport and transform nutrients, is responsible for nutritional ingredient to transport whole body, wraps Include hair;Essence in kidney is the basic of human body, and growth, the maintenance of health status of hair are all closely related with kidney.Qi and blood is homologous, Qi promoting blood production, blood being the material foundation of QI.It can mutually convert, interact between qi and blood.Blood is that flow range is most wide in human body, A kind of body fluid of most abundant nutrition is provided, its organ internal organs each for human body is all closely related.Blood also plays hair Trophism, in the green then hair is also vigorous, and then hair is withered, rare or fall off for blood gas deficiency.When a variety of causes causes blood When dividing lesion, such as blood-head, blood stasis, blood are dry, can all cause the lesion of hair, such as fall off, white hair.
In scalp health management aspect, traditional Chinese medicine has natural advantage.There are many Chinese Ancient Books by the maintenance intelligence of ancients Intelligent to gather, from SUN Si miao " prescriptions worth thousand gold " to Li Shizhen (1518-1593 A.D.) Compendium of Material Medica, all describing many raise scalp has fabulous effect The medicinal herb components of fruit, such as cacumen biotae, Radix Salviae Miltiorrhizae cool blood anti-inflammatory: its cool blood anti-inflammatory effect has excellent effect to oil-control;Ginseng, Radix Angelicae Sinensis, the fleece-flower root can nourish black hair, be aided with natural blood-promoting ingredient, bring sufficient vim and vigour to nourish to scalp, and supply hair is abundant Nutrition.The whole theory of Chinese medicine balance to scalp can go deep into the maintenance of system, adjust scalp grease balance, prevent excessive Grease blocks hair follicle, promotes scalp nutrition supply ability, mildly improves scalp, restores the scalp ecological balance, solves hair oil, head Itch, lead to alopecia problem more than dandruff etc..
Summary of the invention
The purpose of the present invention is to provide a kind of using the entirety of Chinese medicine, balance theory as foundation, multicomponent combination, preparation work The Chinese medicine composition of the phalacrosis prevention and hair generation of skill simplicity, enables people to the health for preferably keeping scalp, quality of making the life better.
It is yet another object of the invention to provide the preparation method of the Chinese medicine composition of above-mentioned phalacrosis prevention and hair generation, enable to realize Industrialized production.
The present invention according to " entirety " idea, is set about, from improvement based on Chinese medicine " balance " theory by alopecia mechanism of production Blood supply reinforces many-sided collective effects such as scalp nutrition, antibacterial, dredging head pore in scalp.Inventor, which selects, to be had Cooling and activating blood, dispelling wind and arresting itching are tonified the liver and kidney, and the Chinese medicine for restoring scalp hair follicles health is thoroughly changed by whole machine balancing theory prescription Kind scalp function, prevents hair from falling off too early, promotes hair growth.
The raw medicinal material component and its quality proportioning of a kind of pharmaceutical composition for phalacrosis prevention and hair generation of the invention are as follows:
10-35 parts of cacumen biotae, 1-20 parts of mulberry leaf, 1-20 parts of eclipta, 1-20 parts of the fleece-flower root, 1-20 parts of pine needle, fructus viticis 1-20 Part, 1-10 parts of Radix Angelicae Sinensis, 1-10 parts of Rhizoma Chuanxiong.
The raw medicinal material component and its quality proportioning of a kind of pharmaceutical composition being preferably used in phalacrosis prevention and hair generation of the invention It is as follows:
15-35 parts of cacumen biotae, 5-15 parts of mulberry leaf, 5-15 parts of eclipta, 5-15 parts of the fleece-flower root, 5-15 parts of pine needle, fructus viticis 5-15 Part, 3-8 parts of Radix Angelicae Sinensis, 3-8 parts of Rhizoma Chuanxiong.
A kind of more preferably raw medicinal material component and its quality proportioning for the pharmaceutical composition of phalacrosis prevention and hair generation of the invention It is as follows:
20 parts of cacumen biotae, 10 parts of mulberry leaf, 10 parts of eclipta, 10 parts of the fleece-flower root, 10 parts of pine needle, 10 parts of fructus viticis, 5 parts of Radix Angelicae Sinensis, river 5 parts of rhizome of chuanxiong.
In above-mentioned raw materials:
Cacumen biotae is the drying branch and leaf of cupressaceae plant arbor-vitae (Platycladus orientalis).Bitter, it is cold in nature, enter Liver Channel, can cool blood black hair.
Mulberry leaf are the dried leaf of moraceae plants mulberry (Folium Mori).It is bitter, sweet, it is cold in nature.Return lung, Liver Channel.Evacuate wind Heat, clearing away the lungheat and moisturizing, calming the liver and improving eyesight, cooling blood and hemostasis.
Eclipta is the aerial part of compositae plant Eclipta prostrata (Eclipta prostrasta).Its is cool in nature, acid sweet in flavor, tool There is the effect of cooling blood and hemostasis, tonifying kidney and benefiting sperm.
The fleece-flower root is the root tuber of polygonum multiflorum thunb (Polygonum multiflorum).Its slightly warm in nature, bitter, It is sweet, puckery, have effects that tonify the liver and kidney, benefiting essence-blood, strengthen the bone.
Pine needle is the various plants such as pinaceae plant Huashan pine, Pinus taiwanesis, masson pine, black pine, Chinese pine, pinus yunnanensis, Korean pine Needle.It is sour, it is bitter, it is warm-natured, it is nontoxic.Enter the heart, spleen, Liver Channel.It can dispel pathogenic wind and remove dampness, desinsection is antipruritic.
Fructus viticis is Verbenaceae Vitex rotundifolia (Vitex trifolia var. simplicifolia) or climing The dry mature fruit of chaste tree (Vitex trifolia).Acrid flavour, hardship, cold nature.Return lung, bladder, Liver Channel.Its primary efficacy is thin Dissipating wind-heat, head clearing, dehumidifying.
Radix Angelicae Sinensis is the dry root of umbelliferae angelica (Angelica sinensis).With enrich blood, invigorate blood circulation, menstruation regulating stops Bitterly, the effect of moisturizing dryness and lubricating intestine.
Rhizoma Chuanxiong is the dry rhizome of umbelliferae Rhizoma Chuanxiong (Ligusticum chuanxiong).Taste is acrid in flavour and warm in nature.It can promoting blood circulation Promoting the circulation of qi, wind-expelling pain-stopping.
Above-mentioned medicinal material should meet the regulation in " Chinese Pharmacopoeia " 2015 version one under each medicinal material item.
The Chinese medicine composition preparation method for the phalacrosis prevention and hair generation that inventor provides is: taking cacumen biotae, mulberry leaf, eclipta, He Shou 8 kinds of crow, pine needle, fructus viticis, Radix Angelicae Sinensis, Rhizoma Chuanxiong medicinal materials are by soaking in water after selected, and then heating and refluxing extraction, is obtained by filtration and mentions Take liquid;Secondary back extract after, combined extract, after concentration, removal precipitating, then carry out secondary concentration to debita spissitudo to get The active constituent of the Chinese medicine composition of phalacrosis prevention and hair generation.
The application method of the Chinese medicine composition of phalacrosis prevention and hair generation of the invention is direct using or as production phalacrosis prevention and hair generation The raw material of the hair washing of cosmetics daily use chemicals class or hair care or hair tonic class product.
Compared with prior art, the invention has the benefit that pure Chinese medicine composition;Raw material is simple, and technique is uncomplicated, real It is strong with property;Curative effect is good, and effective percentage 90% is above.
Specific embodiment
In order to make the summary of the invention in the present invention easily facilitate understanding, below in conjunction with specific embodiment in the present invention The production method is further elaborated.Examples are merely exemplary for these, does not constitute and appoints to the scope of the present invention What is limited.Without departing from the spirit and scope of the invention can details to technical solution of the present invention and form modify or Replacement, but these modifications and replacement are fallen within the protection scope of the present invention.
Raw material employed in following embodiment, is all made of commercial product.
Embodiment:
20 parts of cacumen biotae, 10 parts of mulberry leaf, 10 parts of eclipta, 10 parts of the fleece-flower root, 10 parts of pine needle, 10 parts of fructus viticis, 5 parts of Radix Angelicae Sinensis, river 5 parts of rhizome of chuanxiong.
The Chinese medicine composition of the phalacrosis prevention and hair generation the preparation method is as follows:
Take cacumen biotae, mulberry leaf, eclipta, the fleece-flower root, pine needle, fructus viticis, Radix Angelicae Sinensis, 8 kinds of medicinal materials of Rhizoma Chuanxiong by after selected in proportion Each raw material is weighed, is soaked in water, then heating and refluxing extraction, extracting solution is obtained by filtration;After secondary back extracts, merges and extract Liquid, after concentration, removal precipitating, then carry out secondary concentration to debita spissitudo to get phalacrosis prevention and hair generation Chinese medicine composition activity at Point.Dilutable water is for having one's hair wash, once a day;Or it is applied directly to scalp, it is each primary daily morning and evening.
The Chinese medicine composition prepared in Example carries out following tests, and experimenter is different degrees of hair loss patient, It is primary with the hair washing of the composition water diluent daily, and the composition active constituent is applied at alopecia daily morning and evening, the course for the treatment of It was limited with 3 months, hair hair loss state is observed after the course for the treatment of.
The result of clinical observation of the present invention is as follows: patient totally 78 of statistics are participated in using the test treatment of same method, It is age minimum 28 years old, 63 years old maximum, wherein 28 ~ 35 years old 24,35 ~ 50 years old 33,50 ~ 63 years old 21.Actual use observation obtains Satisfied curative effect, after 3 months courses for the treatment of, effective 42, effective 29, invalid 7, total effective rate is up to 91.02%.

Claims (5)

1. a kind of Chinese medicine composition of phalacrosis prevention and hair generation, it is characterised in that the raw medicinal material component and its quality of the pharmaceutical composition are matched Than as follows: 10-35 parts of cacumen biotae, 1-20 parts of mulberry leaf, 1-20 parts of eclipta, 1-20 parts of the fleece-flower root, 1-20 parts of pine needle, fructus viticis 1- 20 parts, 1-10 parts of Radix Angelicae Sinensis, 1-10 parts of Rhizoma Chuanxiong.
2. a kind of Chinese medicine composition of phalacrosis prevention and hair generation according to claim 1, it is characterised in that the original of the pharmaceutical composition Expect that medicinal material component and its quality proportioning are as follows: 15-35 parts of cacumen biotae, 5-15 parts of mulberry leaf, 5-15 parts of eclipta, fleece-flower root 5-15 Part, 5-15 parts of pine needle, 5-15 parts of fructus viticis, 3-8 parts of Radix Angelicae Sinensis, 3-8 parts of Rhizoma Chuanxiong.
3. a kind of Chinese medicine composition of phalacrosis prevention and hair generation according to claim 1, it is characterised in that the original of the pharmaceutical composition Expect that medicinal material component and its quality proportioning are as follows: 20 parts of cacumen biotae, 10 parts of mulberry leaf, 10 parts of eclipta, 10 parts of the fleece-flower root, pine needle 10 Part, 10 parts of fructus viticis, 5 parts of Radix Angelicae Sinensis, 5 parts of Rhizoma Chuanxiong.
4. preparing the preparation method of claims 1 or 2 or 3 Chinese medicine compositions, it is characterised in that active constituent is by following step Suddenly it is made: 8 kinds of cacumen biotae, mulberry leaf, eclipta, the fleece-flower root, pine needle, fructus viticis, Radix Angelicae Sinensis, Rhizoma Chuanxiong medicinal materials being taken to pass through selected rear plus water It impregnates, then heating and refluxing extraction, is obtained by filtration extracting solution;After secondary back extracts, combined extract, after concentration, removal is heavy It forms sediment, then carries out active constituent of the secondary concentration to debita spissitudo to get the Chinese medicine composition of phalacrosis prevention and hair generation.
5. method as claimed in claim 4, it is characterised in that the active constituent of drug of the present invention is added or is added without auxiliary material, can It is prepared into hair washing or hair care or the hair tonic class product of cosmetics daily use chemicals class.
CN201910601599.7A 2019-07-09 2019-07-09 A kind of Chinese medicine composition of phalacrosis prevention and hair generation and preparation method thereof Pending CN110279775A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111494496A (en) * 2020-05-29 2020-08-07 谢文月 Traditional Chinese medicine composition for growing and blackening hair and preparation method and application thereof
CN112120996A (en) * 2020-10-24 2020-12-25 广东汉粹生物药业有限公司 Plant hair-cleaning powder and preparation method thereof
CN112121135A (en) * 2020-09-28 2020-12-25 广西高企科技有限公司 Traditional Chinese medicine hair conditioner for scalp and hair care and preparation method thereof
CN112245349A (en) * 2020-10-24 2021-01-22 广东汉粹生物药业有限公司 Shampoo containing plant and peptide active components and preparation method thereof
CN112315871A (en) * 2020-09-28 2021-02-05 广西高企科技有限公司 Traditional Chinese medicine shampoo for scalp and hair care and preparation method thereof
CN112773748A (en) * 2021-03-11 2021-05-11 广州文晖医药科技有限公司 Traditional Chinese medicine shampoo for treating seborrheic alopecia and application thereof
CN115590793A (en) * 2022-09-08 2023-01-13 河南中医药大学(Cn) Traditional Chinese medicine washing and caring liquid for improving sub-health state of scalp and hair and preparation method and application thereof

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CN103393830A (en) * 2013-08-22 2013-11-20 常熟华港制药有限公司 Anti-losing and hair growing externally-used traditional Chinese medicine preparation

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CN103393830A (en) * 2013-08-22 2013-11-20 常熟华港制药有限公司 Anti-losing and hair growing externally-used traditional Chinese medicine preparation

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徐宜厚编著: "《徐宜厚皮肤病临证经验笔录》", 31 May 2019, 中国医药科技出版社 *
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111494496A (en) * 2020-05-29 2020-08-07 谢文月 Traditional Chinese medicine composition for growing and blackening hair and preparation method and application thereof
CN112121135A (en) * 2020-09-28 2020-12-25 广西高企科技有限公司 Traditional Chinese medicine hair conditioner for scalp and hair care and preparation method thereof
CN112315871A (en) * 2020-09-28 2021-02-05 广西高企科技有限公司 Traditional Chinese medicine shampoo for scalp and hair care and preparation method thereof
CN112120996A (en) * 2020-10-24 2020-12-25 广东汉粹生物药业有限公司 Plant hair-cleaning powder and preparation method thereof
CN112245349A (en) * 2020-10-24 2021-01-22 广东汉粹生物药业有限公司 Shampoo containing plant and peptide active components and preparation method thereof
CN112773748A (en) * 2021-03-11 2021-05-11 广州文晖医药科技有限公司 Traditional Chinese medicine shampoo for treating seborrheic alopecia and application thereof
CN115590793A (en) * 2022-09-08 2023-01-13 河南中医药大学(Cn) Traditional Chinese medicine washing and caring liquid for improving sub-health state of scalp and hair and preparation method and application thereof
CN115590793B (en) * 2022-09-08 2023-09-15 河南中医药大学 Traditional Chinese medicine washing and caring liquid for improving sub-health state of scalp and hair, and preparation method and application thereof

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