CN1102784A

CN1102784A - Chinese patent medicine for prevention and control of ischemic cardio-cerebral angiopathy

Info

Publication number: CN1102784A
Application number: CN 94111257
Authority: CN
Inventors: 钱士明
Original assignee: HONGYU GROUP CO
Current assignee: HONGYU GROUP CO
Priority date: 1994-02-28
Filing date: 1994-02-28
Publication date: 1995-05-24

Abstract

The said inhalation is prepared with Chinese medicinal material including cassia twig, Lignum dalbergiae odoriferae, paeonia lactiflora, Curcuma aromatica, Acorus gramineus, etc., which is passed through water soaking, steam extraction of volatile oil, addition of 95% concentration medical alcohol into volatile oil extracted to result in clear liquid in relative concentration of 0.850-0.870, and bottling. It can quickly relieve clinical symptoms including dizziness, headache, chest chocking and chest pain, eliminate fatigue and refresh by improving microcirculation, raising oxygen carrying capacity of tissue cells and increasing blood supply to tissues.

Description

Chinese patent medicine for prevention and control of ischemic cardio-cerebral angiopathy

The present invention relates to a kind of Chinese patent medicine of preventing and treating ischemic cardio cerebrovascular diseases, especially inhalant dosage form.

The heart, cerebrovascular are the commonly encountered diseases that jeopardizes human health, especially ischemic cardio cerebrovascular diseases, sickness rate height, mortality rate height, disability rate height.China has the million people to die from cerebrovascular every year, about 1,300,000 people of annual new cases, and the cardiovascular diseases is again apparently higher than cerebrovascular disease.Along with the change of the raising of the development of society, people's material life, work rhythm quickening, dietary structure, the age of onset of cardiovascular and cerebrovascular disease ahead of time, sickness rate is in rising trend.Western countries are particularly outstanding.Recent study shows that blood brain core barrel disease has genetic predisposition, World Health Organization (WHO) propose 2000 everybody enjoy health, for reaching this target, the control cardiovascular and cerebrovascular disease seems quite important.

According to the clinical microcirculation of routine cardiovascular and cerebrovascular vessel patient surplus ten thousand, find that various cardiovascular and cerebrovascular disease all have microcirculation dysfunction in various degree, clinical manifestation is dizzy, dizzy, uncomfortable in chest, weak, symptom such as limb is numb, be afraid of cold, and weight is relevant with the microcirculation disturbance degree again.

Purpose of the present invention is exactly according to the inner disease outer treat principle, a kind of Chinese patent medicine of preventing and treating ischemic cardio cerebrovascular diseases is proposed, after people's nasal cavity sucks, be absorbed by the body, improve human body periphery microcirculation function state, alleviate clinical symptoms, improve cerebral ischemia, thereby prevent and treat cardiovascular and cerebrovascular disease effectively.

The objective of the invention is to be achieved through the following technical solutions: with Chinese crude drug insert soak 2～3 hours in the suitable quantity of water after, volatile oil component in the water steam extraction medicine 3～6 hours, with the volatile oil that extracts, add concentration and be 95% medical ethanol, be made into relative density and be 0.850～0.870 supernatant liquid, promptly with the bottle packing.Ramulus Cinnamomi in the Chinese crude drug, or Flos Caryophylli, or Rhizoma Zingiberis, or Fructus Anisi Stellati, or Folium Et Cacumen Murrayae, or Radix Inulae, or Herba Schizonepetae, or Caulis Tinosporae crispae, or Herba Verbenae, or Folium Artemisiae Argyi, or Herba Blumeae Balsamiferae, or Semen Myristicae, or Fructus Psoraleae, or Fructus Piperis Longi, or Fructus cinnamomi immaturus, or Fructus cinnamomi japonici, or Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Epimedii, or cinnamomic content is 5～40%, Saussurea lappa Clarke, or Herba Adenosmae Glutinosi, or Herba Moslae, or Fructus Amomi Rotundus, or Folium Perillae, or Resina Liquidambaris, or Rhizoma Corydalis, or Radix Kadsurae longipedunculatae, or Herba Ardisiae Japonicae, or the content of Lignum Dalbergiae Odoriferae is 3～20%, Radix Paeoniae Rubra, or Fructus Evodiae, or Folium Baeckeae, or Radix Aristolochiae, or the content of Herba Cymbopogonis Citrari is 5～40%, Radix Curcumae, or Herba Lycopi, or Flos Citri grandis, or Fructus Aurantii, or Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), or Fructus Amomi, or Lignum Aquilariae Resinatum, or Rhizoma Cyperi, or Radix Cinnamomi porrecti, or prolong bone perfume (or spice), or the content of Rhizoma Alpiniae Officinarum is 3～20%, Rhizoma Acori Graminei, or Pericarpium Citri junoris, or Folium citri sinensis, or Fructus Citri junoris, or Folium Citri tangerinae or Pericarpium Citri tangerinae, or Herba Menthae 3～20%.In order to improve the result of use of medicine, warming the meridian and promoting blood circulation, promoting the circulation of QI to relieve pain, also can in above-mentioned medicine, add 3～20% Radix Salviae Miltiorrhizae or Rhizoma Curcumae Longae or Semen Persicae or Stigma Croci or Rhizoma Chuanxiong or Olibanum or Myrrha, the Radix Astragali or the Radix Codonopsis of adding 5～40%, adding respectively are 5～20% the Radix Rehmanniae, Radix Rehmanniae Preparata or Radix Angelicae Sinensis, Cortex Moutan, the Poria or the Lignum Pini Nodi of adding 5～20%, the Radix Glycyrrhizae or the Fructus Viticis Cannabifoliae of adding 3～20%.

Technical characterstic of the present invention and result of use:

1, all medical materials all are Chinese medicine, safe, effective, nontoxic and side effect, except that alleviating acute card shape, are applicable to the chronic especially.

2,, promptly can arrive blood circulation rapidly by the nasal mucosa suction because this medicine is an inhalant.With oral comparison, by gastric mucosa, influenced by the gastric acid barrier, the gastric acid effect, the part medicine is destroyed, is difficult for rapid, safety; Compare with intravenous injection, intravenous injection easily causes phlebitis repeatedly, and the puncture of part venous patient is difficulty.

3, through the Jiangsu Prov. People's Hospital, unit clinic trial such as Nanjing drum tower hospital, Jiangsu Inst. of Traditional Chinese Medicine shows that this medicine is to multiple cardiovascular and cerebrovascular disease, especially coronary heart disease, angina cordis, cerebral arteriosclerosis, hypertension all have significant curative effect, and total effective rate reaches 93.1%.

4, this medicine can be alleviated clinical symptoms rapidly, as giddy, headache, uncomfortable in chest, chest pain etc.Can allaying tiredness, refreshment, refresh oneself.Electrocardioscopy has the ischemic ST-T of improvement cerebral blood flow to increase, and blood viscosity descends.Zoopery shows, significantly improves microcirculating states such as the heart, brain, intestinal, improves the histiocyte oxygen carrying capacity, increases to organize blood to supply.

Realize best way of the present invention:

1, get 5% Ramulus Cinnamomi, 10% Lignum Dalbergiae Odoriferae, 15% Radix Paeoniae Rubra, 10% Radix Curcumae, 5% Rhizoma Acori Graminei, 10% Radix Salviae Miltiorrhizae, 15% the Radix Astragali, respectively be 5% the Radix Rehmanniae, Radix Rehmanniae Preparata, 10% Poria, 10% Radix Glycyrrhizae, insert and soak after 3 hours in the suitable quantity of water, volatile oil in the water steam extraction medicine 4 hours, it is 95% medical ethanol that volatile oil is added concentration, be made into relative density and be 0.850～0.870 supernatant liquid, with the bottle packing promptly, through clinical verification, has drug effect.

2, get 25% Ramulus Cinnamomi, 5% Lignum Dalbergiae Odoriferae, 15% Radix Paeoniae Rubra, 5% Radix Curcumae, 5% Rhizoma Acori Graminei, 5% Radix Salviae Miltiorrhizae, 10% the Radix Astragali, 10% the Radix Rehmanniae, 10% Radix Rehmanniae Preparata, 5% Poria, 5% Radix Glycyrrhizae, produce promptly,, have drug effect through clinical verification according to preceding method.

3, get 30% Ramulus Cinnamomi, 15% Lignum Dalbergiae Odoriferae, 5% Radix Paeoniae Rubra, 14% Radix Curcumae, 10% Rhizoma Acori Graminei, 3% Radix Salviae Miltiorrhizae, 5% the Radix Astragali, 5% the Radix Rehmanniae, 5% Radix Rehmanniae Preparata, 5% Poria, 3% Radix Glycyrrhizae, produce promptly,, have drug effect through clinical verification according to preceding method.

Claims

1, a kind of Chinese patent medicine of preventing and treating ischemic cardio cerebrovascular diseases, it is characterized in that be by Chinese crude drug is inserted soak 2～4 hours in the suitable quantity of water after, volatile oil component in the water steam extraction medicine 3～6 hours, it is 95% medical ethanol that the volatile oil that extracts is added concentration, be made into relative density and be 0.850～0.870 supernatant liquid, with the bottle packing promptly, Ramulus Cinnamomi in the Chinese crude drug, or Flos Caryophylli, or Rhizoma Zingiberis, or Fructus Anisi Stellati, or Folium Et Cacumen Murrayae, or Radix Inulae, or Herba Schizonepetae, or Caulis Tinosporae crispae, or Herba Verbenae, or Folium Artemisiae Argyi, or Herba Blumeae Balsamiferae, or Semen Myristicae, or Fructus Psoraleae, or Fructus Piperis Longi, or Fructus cinnamomi immaturus, or Fructus cinnamomi japonici, or Cortex cinnamomi japonici (Ramulus Cinnamomi), or Herba Epimedii, or cinnamomic content is 5～40%, Saussurea lappa Clarke, or Herba Adenosmae Glutinosi, or Herba Moslae, or Fructus Amomi Rotundus, or Folium Perillae, or Resina Liquidambaris, or Rhizoma Corydalis, or Radix Kadsurae longipedunculatae, or Herba Ardisiae Japonicae, or the content of Lignum Dalbergiae Odoriferae is 3～20%, Radix Paeoniae Rubra, or Fructus Evodiae, or Folium Baeckeae, or Radix Aristolochiae, or the content of Herba Cymbopogonis Citrari is 5～40%, Radix Curcumae, or Herba Lycopi, or Flos Citri grandis, or Fructus Aurantii, or Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), or Fructus Amomi, or Lignum Aquilariae Resinatum, or Rhizoma Cyperi, or Radix Cinnamomi porrecti, or prolong bone perfume (or spice), or the content of Rhizoma Alpiniae Officinarum is 3～20%, Rhizoma Acori Graminei, or Pericarpium Citri junoris, or Folium citri sinensis, or Pericarpium citri sinensis, or Folium Citri tangerinae, or Pericarpium Citri tangerinae, or the content of Herba Menthae is 3～20%.

2, a kind of Chinese patent medicine of preventing and treating ischemic cardio cerebrovascular diseases of narrating according to claim 1 is characterized in that also containing in the Chinese crude drug 3～20% Radix Salviae Miltiorrhizae or Rhizoma Curcumae Longae or Semen Persicae or Stigma Croci or Rhizoma Chuanxiong or Olibanum or Myrrha.

3, a kind of Chinese patent medicine of preventing and treating ischemic cardio cerebrovascular diseases of being narrated according to claim 1 or 2 is characterized in that also containing in the Chinese crude drug 5～40% the Radix Astragali or Radix Codonopsis.

4, a kind of Chinese patent medicine of preventing and treating ischemic cardio cerebrovascular diseases of being narrated according to claim 1 or 2 is characterized in that also containing respectively in the Chinese crude drug 5～20% the Radix Rehmanniae, Radix Rehmanniae Preparata or Radix Angelicae Sinensis, Cortex Moutan.

5, a kind of Chinese patent medicine of preventing and treating ischemic cardio cerebrovascular diseases of being narrated according to claim 1 or 2 is characterized in that also containing in the Chinese medicine 5～20% Poria or Lignum Pini Nodi.

6, a kind of Chinese patent medicine of preventing and treating ischemic cardio cerebrovascular diseases of being narrated according to claim 1 or 2 is characterized in that also containing in the Chinese crude drug 3～20% Radix Glycyrrhizae or Fructus Viticis Cannabifoliae.