CN102861241B

CN102861241B - Traditional Chinese medicine qi-reinforcing and stasis-removing soup for treating acute myocardial infarction

Info

Publication number: CN102861241B
Application number: CN201210364689.7A
Authority: CN
Inventors: 宋燕
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-09-18
Filing date: 2012-09-18
Publication date: 2014-06-18
Anticipated expiration: 2032-09-18
Also published as: CN102861241A

Abstract

The invention discloses traditional Chinese medicine qi-reinforcing and stasis-removing soup for treating acute myocardial infarction. The acute myocardial infarction belongs to the range of 'chest obstruction' and 'angina pectoris' of the traditional Chinese medicine. The disease location of the acute myocardial infarction is the heart of a human body, the deficiency is the cause, cold congealing, qi stagnation, blood stasis and phlegm are symptoms, and the nature of the disease is shown as deficient cause with overdo superficial and intermingled deficiency and excess. Accordingly, traditional Chinese medicinal materials such as fruits of camphor trees, roots of divaricate knotweed herbs, roots of kerr treebine, licorice, radix puerariae, astragalus membranaceus, lignum dalbergiae odoriferae, salvia miltiorrhiza, ligusticum chuanxiong, saffron crocus, fructus aurantii, ladybell roots and dendrobium which have effects of clearing heat, eliminating phlegm, promoting blood circulation to remove blood stasis, supplementing qi and nourishing yin are selected and prepared into the soup. As clinical tests on 144 patients in a hospital, total effective rate reaches 97.2%, a perfect curative effect is realized, and the traditional Chinese medicine qi-reinforcing and stasis-removing soup is worthy of being clinically popularized and applied.

Description

A kind of Chinese medicine QI invigorating Huayu Tang for the treatment of acute myocardial infarction

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine QI invigorating Huayu Tang for the treatment of acute myocardial infarction.

Background technology

Acute myocardial infarction is again in acute myocardial infarction, and morbidity is anxious, and change of illness state is fast, easily complicated by arrhythmia, heart failure, cardiogenic shock etc., and case fatality rate, up to 6%～30%, is the clinical common critical illness of emergency treatment.Conventional treatment comprises strict bed rest, oxygen uptake, cardio-pulmonary resuscitation, thrombolytic, arrhythmia etc. clinically.My institute proves through clinical research for many years, utilizes Chinese medicine symptomatic treatment can improve significantly the generation for the treatment of success rate and minimizing complication.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine QI invigorating Huayu Tang for the treatment of acute myocardial infarction.Acute myocardial infarction belongs to motherland's medical science " thoracic obstruction ", " angina pectoris " category.The sick position of primary disease is at the heart, and taking void as this, cold coagulation, the stagnation of QI, blood stasis, expectorant is turbid is mark, and characteristic of disease is the card of deficiency in origin and excess in superficiality, simulataneous insufficiency and excessive.The traditional Chinese medical science treatment on taking removing heat-phlegm, blood circulation promoting and blood stasis dispelling, supplementing QI and nourishing YIN as the rule for the treatment of.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine QI invigorating Huayu Tang of this treatment acute myocardial infarction is made up of the Chinese medicine of following weight portion: Fructus litseae rubescentis 10-15 part, Radix polygoni divaricati 10-15 part, Radix Cissi Kerrii 10-12 part, Radix Glycyrrhizae 5-7 part, Radix Puerariae 13-15 part, Radix Astragali 15-20 part, Lignum Dalbergiae Odoriferae 9-11 part, Radix Salviae Miltiorrhizae 14-16 part, Rhizoma Chuanxiong 11-13 part, Stigma Croci 8-10 part, Fructus Aurantii 9-11 part, Radix Adenophorae 11-13 part, Herba Dendrobii 11-13 part.

Preferably, 13 parts of Fructus litseae rubescentis, 13 parts of Radix polygoni divaricaties, 11 parts of Radix Cissi Kerrii, 6 parts, Radix Glycyrrhizae, 14 parts of Radix Puerariaes, 18 parts of the Radixs Astragali, 10 parts of Lignum Dalbergiae Odoriferaes, 15 parts of Radix Salviae Miltiorrhizaes, 12 parts of Rhizoma Chuanxiongs, 9 parts of Stigma Crocis, 10 parts of Fructus Aurantiis, 12 parts of Radix Adenophoraes, 12 parts of Herba Dendrobiis.

Preparation method is made decoction by above-mentioned Chinese medicine by traditional method.

Fang Zhong: Fructus litseae rubescentis: expelling wind and cold, relieving dyspepsia; Radix polygoni divaricati: the kidney warming of dispeling cold; Radix Cissi Kerrii: heat-clearing and toxic substances removing, eliminating stagnation promoting the circulation of blood; Radix Glycyrrhizae: QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, alleviates pain relieving; Radix Puerariae: expelling pathogenic factors from muscles for reducing heat, treating measles, promoting the production of body fluid to quench thirst; The Radix Astragali: the raw sun of QI invigorating, benefit is consolidating superficial resistance, inducing diuresis to remove edema, holder skin ulcer life; Lignum Dalbergiae Odoriferae: removing stasis to stop bleeding, regulating QI to relieve pain.Radix Salviae Miltiorrhizae: promoting blood flow to regulate menstruation, removing heat from blood eliminating carbuncle, calms the nerves; Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping; Stigma Croci; Blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens; Fructus Aurantii: dispelling the stagnated QI is except painful abdominal mass, transforming phlegm and dispersing accumulations; Radix Adenophorae: nourishing YIN and clearing away lung-heat, the QI invigorating of reducing phlegm; Herba Dendrobii: replenishing YIN and removing heat, reinforcing stomach reg fluid.

Clinical data

The selected 144 routine cases of physical data meet Diagnosis of Acute Myocardial Infarction standard, all, from February, 2002～2008 patient that year accept for medical treatment in emergency department of Jian Wo institute in November ward, are divided at random two groups, treatment group 72 examples, wherein male 43 examples, female's 29 examples; 40～79 years old age, average 63.1 years old; Matched group 72 examples, wherein male 45 examples, female's 27 examples; 41～77 years old age, average 62.5 years old.Two groups of patients' morbidity is to data Epidemiological Analysis processing by statistics such as admission time, severity extent, infarction position, age, sexes, and no significant difference (P > 0.05), illustrates that two groups of data have comparability.

Diagnostic criteria chest pain continues > 30min, and rest and buccal nitroglycerin are not alleviated; At least two the adjacent S-T of leading sections of electrocardiogram are raised; In morbidity 6h; Without thrombolytic contraindication; All be diagnosed as acute myocardial infarction; Tcm syndrome standard: the vexed pain in ambition or causalgia connect and back, accompany vomiting and nausea uncomfortable in chest, bitter taste abundant expectoration, insomnia and dreamful sleep, large dry stool, dimly red tongue, yellow and thin fur or yellow greasy, rolling pulse or sliding number.

Therapeutic Method treatment group is taken Chinese medicine Chinese medicine QI invigorating Huayu Tang of the present invention, every day potion, early, evening point secondary clothes; The oral isosorbide dinitrate tablets sublingual administration of matched group, sorbitrate, aspirin; Two groups of homogeneous Zhou Weiyi courses for the treatment of.

The criterion of criterion of therapeutical effect clinical efficacy is with reference to " new Chinese medicine guideline of clinical investigations " (first volume, version in 1993) curative effect determinate standard of " guideline of clinical investigations of the new Chinese medicine treatment thoracic obstruction (angina pectoris) " drafts: effective: clinical symptom disappearance, it is normal that myocardial zymetology recovers, and ECG ST section recovers normally or only to stay pathologic Q ripple and (or) coronary T wave; Effective: clinical symptoms disappears substantially, electrocardiogram has Q to involve the change that ST-T takes a turn for the better; Invalid: clinical symptoms is not alleviated, electrocardiogram is without improvement, even dead.

Two groups of treatments of therapeutic outcome are added up curative effect after two courses for the treatment of, treatment group 72 effective 50 examples of example (69.4%), and effective 20 examples (27.8%), invalid 2 examples (2.8%), total effective rate reaches 97.2%; Matched group 72 effective 30 examples of example (41.7%), effective 29 examples (40.3%), invalid 13 examples (18.1%), total effective rate reaches 81.9%; Two groups control obvious effective rate, total effective rate has significant difference (P < 0.05).

Detailed description of the invention

Embodiment mono-: take Fructus litseae rubescentis 13g, Radix polygoni divaricati 13g, Radix Cissi Kerrii 11g, Radix Glycyrrhizae 6g, Radix Puerariae 14g, Radix Astragali 18g, Lignum Dalbergiae Odoriferae 10g, Radix Salviae Miltiorrhizae 15g, Rhizoma Chuanxiong 12g, Stigma Croci 9g, Fructus Aurantii 10g, Radix Adenophorae 12g, Herba Dendrobii 12g, make according to a conventional method decoction, every day potion, early, evening point secondary clothes.

Embodiment bis-: take Fructus litseae rubescentis 10g, Radix polygoni divaricati 10g, Radix Cissi Kerrii 10g, Radix Glycyrrhizae 5g, Radix Puerariae 13g, Radix Astragali 15g, Lignum Dalbergiae Odoriferae 9g, Radix Salviae Miltiorrhizae 14g, Rhizoma Chuanxiong 11g, Stigma Croci 8g, Fructus Aurantii 9g, Radix Adenophorae 11g, Herba Dendrobii 11g makes decoction according to a conventional method, every day potion, early, evening point secondary clothes.

Embodiment tri-: take Fructus litseae rubescentis 15g, Radix polygoni divaricati 15g, Radix Cissi Kerrii 12g, Radix Glycyrrhizae 7g, Radix Puerariae 15g, Radix Astragali 20g, Lignum Dalbergiae Odoriferae 11g, Radix Salviae Miltiorrhizae 16g, Rhizoma Chuanxiong 13g, Stigma Croci 10g, Fructus Aurantii 11g, Radix Adenophorae 13g, Herba Dendrobii 13g makes decoction according to a conventional method, every day potion, early, evening point secondary clothes.

Claims

1. treat a Chinese medicine QI invigorating Huayu Tang for acute myocardial infarction, it is characterized in that this Chinese medicine QI invigorating Huayu Tang is made up of the Chinese medicine of following weight portion: Fructus litseae rubescentis 13g, Radix polygoni divaricati 13g, Radix Cissi Kerrii 11g, Radix Glycyrrhizae 6g, Radix Puerariae 14g, Radix Astragali 18g, Lignum Dalbergiae Odoriferae 10g, Radix Salviae Miltiorrhizae 15g, Rhizoma Chuanxiong 12g, Stigma Croci 9g, Fructus Aurantii 10g, Radix Adenophorae 12g, Herba Dendrobii 12g.