CN110261635B - Full-automatic biochemical analysis method - Google Patents
Full-automatic biochemical analysis method Download PDFInfo
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- CN110261635B CN110261635B CN201910698829.6A CN201910698829A CN110261635B CN 110261635 B CN110261635 B CN 110261635B CN 201910698829 A CN201910698829 A CN 201910698829A CN 110261635 B CN110261635 B CN 110261635B
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- 238000000034 method Methods 0.000 title claims abstract description 25
- 238000012742 biochemical analysis Methods 0.000 title claims abstract description 17
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 171
- 238000001514 detection method Methods 0.000 claims abstract description 146
- 238000002360 preparation method Methods 0.000 claims abstract description 116
- 238000012546 transfer Methods 0.000 claims abstract description 81
- 230000007246 mechanism Effects 0.000 claims description 64
- 238000013519 translation Methods 0.000 claims description 17
- 238000009434 installation Methods 0.000 claims description 10
- 230000035939 shock Effects 0.000 claims description 10
- 238000004458 analytical method Methods 0.000 claims description 6
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- 230000000694 effects Effects 0.000 description 3
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- 238000005259 measurement Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 238000007599 discharging Methods 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
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- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010876 biochemical test Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
- G01N2035/00356—Holding samples at elevated temperature (incubation)
- G01N2035/00376—Conductive heating, e.g. heated plates
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
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Abstract
The invention discloses a full-automatic biochemical analysis method, which comprises the following steps: the reagent disc detection device is characterized by comprising a shell, an outer ring turntable assembly, an inner ring turntable assembly, a disc transfer assembly, a preparation station, a detection station, a warehouse inlet assembly, a constant temperature assembly and a detection device, wherein the outer ring turntable assembly, the inner ring turntable assembly, the disc transfer assembly, the preparation station, the detection station, the warehouse inlet assembly, the warehouse outlet assembly, the constant temperature assembly and the detection device are arranged in the shell, the preparation station is provided with a plurality of preparation stations which are annularly distributed on the outer ring turntable assembly, the detection station is provided with at least two inner ring turntable assemblies which are uniformly distributed, the preparation station and the detection station can rotate, the inner ring turntable assembly is positioned in the middle of the outer ring turntable assembly, and the outer ring turntable assembly can drive the preparation station to rotate.
Description
Technical Field
The invention relates to an analysis method, in particular to a full-automatic biochemical analysis method.
Background
Biochemical analyzers, also commonly referred to as biochemics, are instruments that use the principle of optoelectric colorimetry to measure a particular chemical component in a body fluid. Because of its fast measuring speed, high accuracy and small reagent consumption, it is widely used in hospitals, epidemic prevention stations and family planning service stations. The efficiency and the income of the conventional biochemical test can be greatly improved by matching the use; the automatic biochemical analyzer can perform analysis and measurement of various reaction types such as a timing method, a continuous monitoring method and the like. Besides the measurement of general biochemical items, the method can also be applied to the measurement of special compounds such as hormone, immunoglobulin, blood concentration and the like and analysis methods such as enzyme immunization, fluorescence immunization and the like; it has the characteristics of rapidness, simplicity, convenience, sensitivity, accuracy, standardization, trace and the like.
In practice, when biochemical analysis is performed, only one reagent disk is often analyzed, after the reagent disk is placed into an analyzer, a centrifugation process is firstly performed, then the reagent disk is detected, and finally the reagent disk after detection is moved out of the analyzer.
Disclosure of Invention
The invention aims to overcome the defects that the detection speed is low and continuous detection cannot be carried out when a reagent disk is detected in the prior art, and provides a full-automatic biochemical analysis method which can effectively improve the detection efficiency of the reagent disk and can realize the continuous detection of the reagent disk.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows:
a full-automatic biochemical analysis method comprises the following steps: enabling the reagent tray to enter an analyzer, detecting the reagent tray after the reagent tray is subjected to a centrifugal preparation process, and moving the reagent tray after detection out of the analyzer; the analyzer comprises an outer ring turntable assembly, an inner ring turntable assembly, a disc transfer assembly, a preparation station, a detection station, an in-out bin assembly, a constant temperature assembly and a detection device which are arranged in a shell, the preparation stations are provided with a plurality of detection stations which are distributed on the outer ring rotating disc component in an annular mode, the detection stations are provided with at least two detection stations which are distributed on the inner ring rotating disc component in an evenly distributed mode, the preparation station and the detection station can rotate, the inner ring turntable assembly is positioned in the middle of the outer ring turntable assembly, the outer ring turntable assembly can drive the preparation station to rotate, the inner ring turntable assembly can drive the detection station to rotate, the in-out bin assembly is used for delivering and feeding the reagent tray, the detection device is used for detecting the reagent tray, the constant temperature component is used for keeping the interior constant temperature, and the disk transfer component is used for transferring the reagent disk among the in-out bin component, the preparation station and the detection station;
the steps are as follows:
s1: starting the analyzer, enabling the reagent disk to be detected to enter the analyzer through the in-out bin assembly, identifying the reagent disk, and acquiring to-be-detected information of the reagent disk to be detected;
s2: the reagent disk is transferred to a preparation station on the outer ring turntable assembly by the disk transfer assembly to carry out a centrifugal preparation process, the preparation station determines the preparation time and the rotation speed of the preparation station according to the acquired information to be detected, and after the previous reagent disk to be detected is placed, the outer ring turntable assembly rotates to enable the idle preparation station to rotate to the moving path of the disk transfer assembly and enter a disk receiving state; the disc transfer assembly transfers the subsequent reagent disc to an idle preparation station in a return stroke, and the steps are circulated in such a way to finish the preparation process before the detection of the reagent disc, wherein one preparation station needs to be kept in an idle state;
s3: firstly, a to-be-detected reagent disk entering a preparation station firstly completes the preparation process, the to-be-detected reagent disk is transferred to a detection station on an inner ring turntable assembly through a disk transfer assembly, the detection station drives the reagent disk to rotate, the inner ring turntable assembly drives the detection station to rotate to a detection device for detection, and an idle detection station enters a to-be-connected disk state;
s4: the tray transfer assembly transfers a new reagent tray to an idle preparation station in a return stroke, or transfers the reagent tray which has finished the preparation process to an idle detection station to wait for detection;
s5: after the detection of the first detected reagent disk is finished, the inner ring turntable assembly rotates, a new reagent disk is rotated to the detection device for detection, the detected reagent disk rotates to the position below the path of the disk transfer assembly, and is dispatched out of the analyzer through the disk transfer assembly, and the detection of the reagent disk is finished;
s5: after the detected reagent tray is transferred out of the analyzer, a tray transfer assembly transfers a new reagent tray to a preparation station in an idle state, transfers the reagent tray which finishes the preparation process to an idle detection station, and enables the reagent tray to enter a state to be detected, and meanwhile, enables the fully loaded preparation station to be idle to be one so as to enable the reagent tray to enter a state of a reagent tray to be received; thus, continuous detection of the reagent tray is realized.
In S2, the in-out bin assembly identifies the reagent tray through an identification device, which is a bar-shaped identification device or a two-dimensional code identification device.
The information to be detected comprises sample information, information to be detected of the sample, sample detection time, sample centrifugal rotating speed information and sample centrifugal direction information.
The outer ring turntable assembly comprises an outer ring fixing support, a rotary disc and a driving device I, the outer ring fixing support is installed on a bottom plate arranged at the bottom in the analyzer shell, the rotary disc is installed on the outer ring fixing support, the driving device I can drive the rotary disc to rotate on the outer ring fixing support, and the preparation station is arranged on the rotary disc.
A plurality of eccentric roller shafts are uniformly distributed on the outer ring fixing support, roller bodies are connected to the eccentric roller shafts through bearings, recesses are formed in the side faces of the roller bodies, and the edges of the rotary discs can be matched with the recesses; the outer ring fixing support is connected with the bottom plate through a support column I, and a shock pad is arranged between the outer ring fixing support and the support column I.
Drive arrangement I includes motor I, gear I and sector I, I installation of motor is on the outer ring fixed bolster, gear I links to each other with motor I, sector I is installed in the gyration dish below, gear I and I intermeshing of sector.
Inner ring carousel subassembly includes base member seat, interior gyration dish, center pin and drive arrangement II, detection device installs on the base member seat, base member seat fixed mounting is on the bottom plate of bottom setting in the analysis appearance casing, the center pin passes through the bearing and vertically installs on the base member seat, interior gyration dish is fixed on the center pin, including the detection station sets up on the gyration dish, drive arrangement II can drive interior gyration dish and rotate.
The driving device II comprises a motor II, a gear II and a sector II, the motor II is installed on the bottom plate through an inner ring motor installation piece, the gear II is connected with the motor II, the sector II is installed below the rotary disc, and the sector II is meshed with the gear II.
The tray transferring assembly comprises an upper cover main support, a lower cover main support, a spring support rod, a lifting mechanism, an absorbing mechanism and a translation mechanism, the lower cover main support is connected with an outer ring turntable assembly, the upper cover main support is hinged to the lower cover main support, the spring support rod is connected between the upper cover main support and the lower cover main support, the translation mechanism is installed on the upper cover main support, the lifting mechanism is installed on the translation mechanism, the absorbing mechanism is installed on the lifting mechanism, the translation mechanism is used for driving the lifting mechanism and the absorbing mechanism to translate towards the direction of the outer ring turntable assembly, the inner ring turntable assembly and the warehouse inlet and outlet assembly, the lifting mechanism is used for driving the absorbing mechanism to vertically move, and the absorbing mechanism is used for tightly absorbing or loosening the reagent tray.
Compared with the prior art, the invention has the following beneficial effects:
the invention mainly realizes the detection of a reagent disk by an analyzer, realizes the warehousing and the warehousing of the reagent disk by a warehousing component, simultaneously transfers the reagent disk in a shell by a disk transfer component, and realizes the allocation and transportation work of the reagent disk in the shell by the principle of first-in first-out, first-in preparation, first-out detection, first-in detection first-out, the reagent disk entering the shell is firstly allocated to a preparation station on an outer ring turntable component by the disk transfer component to be prepared before detection, after the reagent disk on the first-in preparation station finishes the preparation process, the reagent disk is allocated to an inner ring turntable component under the action of the disk transfer component, the turntable component drives the reagent disk to rotate to a detection device to be detected, and the disk transfer component returns to allocate a new reagent disk to an idle preparation station to carry out the preparation process, after the detection of the reagent disk is finished, the tray transfer will transfer to the warehouse entry components and discharge them out of the housing; therefore, the preparation and the detection of the reagent disk are integrated, the reagent disk can be transported to the detection device for detection after the preparation process is finished while the preparation process is carried out, the continuous detection of the reagent disk can be realized, the number of the detected reagent disks is more in the same time, and the detection efficiency is higher.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention.
FIG. 2 is a schematic view of the overall structure of the outer ring turntable assembly of the present invention.
Fig. 3 is an exploded view of fig. 2 of the present invention.
FIG. 4 is a schematic view of the overall structure of the inner ring turntable assembly of the present invention.
FIG. 5 is a schematic view of the overall structure of the tray transfer unit according to the present invention.
FIG. 6 is a schematic view of the connection between the translation mechanism and the lifting mechanism according to the present invention.
FIG. 7 is a schematic view of the connection between the lifting mechanism and the sucking mechanism according to the present invention.
Fig. 8 is an exploded view of fig. 7 in accordance with the present invention.
Fig. 9 is a schematic view of the overall structure of the inlet and outlet assembly of the present invention.
Fig. 10 is a schematic view of the overall structure of the preparation station and the detection station of the present invention.
Fig. 11 is a half sectional view of fig. 10 of the present invention.
Fig. 12 is a schematic structural diagram of a jacking mechanism of the present invention.
Fig. 13 is a schematic view of the cam structure of the present invention.
Fig. 14 is a front view of fig. 13 in accordance with the present invention.
FIG. 15 is a schematic view of the connection between the upper cover main support and the lower cover main support according to the present invention.
Reference numerals: 1 shell, 101 upper shell, 102 lower shell, 2 outer ring turntable component, 201 outer ring fixing bracket, 202 rotary disk, 203 bottom plate, 204 eccentric roller shaft, 205 roller body, 206 support pillar I, 207 shock pad, 208 motor I, 209 gear I, 210 sector I, 3 inner ring turntable component, 301 base seat, 302 inner rotary disk, 303 motor II, 304 gear II, 305 sector II, 4 disk transfer component, 401 upper cover main bracket, 402 lower cover main bracket, 403 spring support rod, 5 translation mechanism, 501 guide rail bracket, 502 guide rod, 503 driving motor, 504 driving pulley, 505 driven pulley, 506 sliding seat, 507 synchronous belt, 508 synchronous belt press block, 509 synchronous belt connecting block, 510 position marking shaft I, 511 optical coupler sensor I, 6 lifting mechanism, 601 lifting motor, 602 upright post, 603 optical coupler sensor II, 604 position marking shaft II, 605 mounting seat, 606 sliding guide rod, 607 leading screw, 608 linear bearing, 609 sliding chute, 610 leading screw nut, 7 sucking mechanism, 701 vacuum chuck, 702 vacuum chuck connecting plate, 801 internal heating fixing plate and 802 internal ring heating plate; heating foam on 901, heating plate on 902, and heating film on 903; 904 upper cover plate, 1001 outer heating plate, 1002 outer ring heating film, 1003 heating cavity upper foam, 1004 heat preservation shell, 1005 gap, 1006 heating cavity upper cover plate, 1101 rack C, 1102 gear C, 1103 motor C, 1104 bin door plate, 1105 guide rod, 1106 induction plate, 1107 upper detection sensor, 1108 lower detection sensor, 1109 guide seat, 12 sliding groove, 13 brush sealing strip, 14 shock absorption column, 15 warehouse in and out component, 1501 guide rail seat, 1502 bracket, 1503 sensor, 1504 disc warehouse out hole, 1505 recognition device, 1506 inclined plane, 1507 disc fixing hole, 1508 motor, 1509 gear, 1510 rack, 16 detection station, 1601 rotating motor, 1602 tray, 1603 push rod, 1604 sliding sleeve, 1605 large spring, 1606 slide block, 1607 sliding core, 1608 small spring, 1609 limit hole, limit groove, 1611 limit ball; 17 preparation station, 18 reagent plate, 1901 cam bracket, 1902 cam, 1903 jacking motor, 1904 fixing shaft, 1905 torsion spring, 1906 first jacking arm, 1907 second jacking arm, 1908 arc notch, 1909 cam surface, 20 detection device.
Detailed Description
The present invention will be further described with reference to the following examples, which are intended to illustrate only some, but not all, of the embodiments of the present invention. Based on the embodiments of the present invention, other embodiments used by those skilled in the art without any creative effort belong to the protection scope of the present invention.
Example 1
A full-automatic biochemical analysis method comprises the following steps: the reagent disk 18 is put into the analyzer, the reagent disk 18 is detected after the reagent disk 18 is subjected to a centrifugation preparation process, and the reagent disk 18 after the detection is finished is removed from the analyzer;
wherein the content of the first and second substances,
the analyzer comprises a shell 1, an outer ring turntable assembly 2, an inner ring turntable assembly 3, a disc transfer assembly 4, a preparation station 17, a detection station 16, a warehouse entry assembly 15, a constant temperature assembly and a detection device 20, wherein the outer ring turntable assembly 2, the inner ring turntable assembly 3, the warehouse entry assembly 15, the constant temperature assembly and the detection device 20 are arranged in the shell 1, the preparation station 17 is provided with a plurality of annular preparation stations which are distributed on the outer ring turntable assembly 2, the detection station 16 is provided with at least two annular detection stations which are uniformly distributed on the inner ring turntable assembly 3, the preparation station 17 and the detection station 16 can rotate, the inner ring turntable assembly 3 is positioned in the middle of the outer ring turntable assembly 2, the outer ring turntable assembly 2 can drive the preparation station 17 to rotate, the inner ring turntable assembly 3 can drive the detection station 16 to rotate, the warehouse entry and exit assembly 15 is used for taking out and entering a reagent disc 18, the detection device 20 is used for detecting the reagent disc 18, the constant temperature, The preparation station 17 and the detection station 16 are dispatched.
Wherein the housing 1 comprises an upper housing 101 and a lower housing 102.
In the present embodiment, there are 5 preparation stations 17 and 2 detection stations 16.
Further preferably, the outer ring turntable assembly 2 includes an outer ring fixing support 201, a rotary disc 202 and a driving device i, the outer ring fixing support 201 is installed on a bottom plate 203 arranged at the bottom in the housing 1, the rotary disc 202 is installed on the outer ring fixing support 201, the driving device i can drive the rotary disc 202 to rotate on the outer ring fixing support 201, and the preparation station 17 is arranged on the rotary disc 202.
The outer ring fixing support 201 mainly plays a supporting role, and the rotary disc 202 is driven by the driving device I, so that the rotary disc 202 can rotate on the outer ring fixing support 201, and the purpose that the rotary disc 202 drives the preparation station 17 to rotate is achieved.
Further preferably, a plurality of eccentric roller shafts 204 are uniformly distributed on the outer ring fixing support 201, the eccentric roller shafts 204 are connected with roller bodies 205 through bearings, recesses are formed in the side surfaces of the roller bodies 205, and the edges of the rotary discs 202 can be matched with the recesses; the outer ring fixing support 201 is connected with the bottom plate 203 through a support column I206, and a shock absorption pad 207 is arranged between the outer ring fixing support 201 and the support column I206.
In this way, the shock absorption pad 207 is arranged between the outer ring fixing part and the support column I206, so that the shock absorption effect can be achieved, the shock caused when the rotary disc 202 rotates can be effectively avoided, and the influence of the detection result of the detection device 20 can be reduced; moreover, the purpose of rotation of the rotary disc 202 can be realized by matching the recess arranged on the roller body 205 with the edge of the rotary disc 202; meanwhile, the rotating disc 202 can be ensured to rotate more smoothly.
Wherein, drive arrangement I includes I208, I209 and the I210 of sector of motor, I208 of motor is installed on outer loop fixed bolster 201, I209 links to each other with I208 of motor of gear, I210 of sector is installed in gyration dish 202 below, I209 and the I210 intermeshing of sector of gear.
Like this, I208 of motor rotates drive gear I209 and rotates, and then the drive rotates with I209 intermeshing's of gear sector I210 to the realization is to the drive of gyration dish 202, and corotation and the corotation of reversal drive gyration dish 202 through I208 of motor adopt sector I210 can effectual reduction occupation volume.
Wherein, inner ring carousel subassembly 3 includes base 301, interior gyration dish 302, center pin and drive arrangement II, detection device 20 installs on base 301, 301 fixed mounting is done to the base member on the bottom plate 203 that the bottom set up in casing 1, the center pin passes through the bearing and vertically installs on base 301, interior gyration dish 302 is fixed on the center pin, detection station 16 sets up on interior gyration dish 302, drive arrangement II can drive interior gyration dish 302 and rotate.
Like this for interior carousel 302 can rotate on base member seat 301, and drive arrangement II drive interior carousel 302 rotates, and then makes detection station 16 can follow interior carousel 302 and rotate, realizes the removal of detection station 16.
The driving device II comprises a motor II 303, a gear II 304 and a sector II 305, the motor II 303 is installed on the bottom plate 203 through an inner ring motor installation piece, the gear II 304 is connected with the motor II 303, the sector II 305 is installed below the inner rotary disc 302, and the sector II 305 is meshed with the gear II 304.
In this way, the motor II 303 drives the gear II 304 to rotate, and the sector II 305 rotates along with the gear II 304, so that the inner rotary disk 302 is driven.
A shock absorption pad 207 is arranged between the base seat 301 and the bottom plate 203.
Thus, vibration generated when the detection station 16 rotates and the motor II 303 operates can be reduced, and the influence on the detection device 20 is reduced.
Further preferably, the tray transferring assembly 4 comprises an upper cover main support 401, a lower cover main support 402, a spring support 403, a lifting mechanism 6, a suction mechanism 7 and a translation mechanism 5, the lower cover main support 402 is connected with the outer ring turntable assembly 2, the upper cover main support 401 and the lower cover main support 402 are hinged with each other, the spring stay 403 is connected between the upper cover main support 401 and the lower cover main support 402, the translation mechanism 5 is arranged on the upper cover main bracket 401, the lifting mechanism 6 is arranged on the translation mechanism 5, the absorbing mechanism 7 is installed on the lifting mechanism 6, the translation mechanism 5 is used for driving the lifting mechanism 6 and the absorbing mechanism 7 to translate towards the direction of the outer ring turntable assembly 2, the inner ring turntable assembly 3 and the in-out bin assembly 15, the lifting mechanism 6 is used for driving the absorbing mechanism 7 to move vertically, and the absorbing mechanism 7 is used for tightly absorbing or loosening the reagent disk 18.
Like this, absorb reagent dish 18 through suction means 7, simultaneously, drive suction means 7 through elevating system 6 and rise or descend to realize the lateral shifting of elevating system and suction means 7 through translation mechanism 5, elevating system 6 and suction means 7 three's synergism, realize the transportation to reagent dish 18.
Wherein, translation mechanism 5 includes guide rail bracket 501, guide bar 502, driving motor 503, driving pulley 504, driven pulley 505, slip seat 506, hold-in range 507, hold-in range briquetting 508, hold-in range connecting block 509, position mark axle I510 and opto-coupler sensor I511, guide rail bracket 501 has two and parallel arrangement on upper cover main support 401, passes through between the guide rail bracket 501 guide bar 502 connects, slip seat 506 and guide bar 502 cooperation, slip seat 506 can move on guide bar 502, driving motor 503 is installed on one of them guide rail bracket 501, driving motor 503 with driving pulley 504 links to each other, driven pulley 505 and opto-coupler sensor I511 install on another guide rail bracket 501, pass through between driving pulley 504 and the driven pulley 505 hold-in range 507 is connected, hold-in range connecting block 509 is connected with slip seat 506, hold-in range briquetting 508 presses hold-in range 507 on hold-in range connecting block 509, the location marks axle I510 and installs on the seat 506 that slides, and opto-coupler sensor I511 is used for detecting the information that targets in place of location mark axle I510, elevating system 6 installs on the seat 506 that slides.
In this way, the driving pulley 504 is driven to rotate by the driving motor 503, the driven pulley 505 also rotates under the action of the synchronous belt 507, and the synchronous belt pressing block 508 presses the synchronous belt 507 on the synchronous belt connecting block 509, so that the sliding seat 506 can move along with the synchronous belt 507, the synchronous belt 507 moves back and forth by the forward and reverse rotation of the driving motor 503, and the sliding seat 506 is driven; moreover, the sliding seat 506 can be more stable when moving through the arranged guide rod 502, and the transferring process of the reagent disk 18 is safer.
The lifting mechanism 6 comprises a lifting motor 601, a vertical column 602, an optical coupling sensor II 603, a position marking shaft II 604, an installation seat 605, a sliding guide rod 606, a screw 607 and a linear bearing 608, wherein the installation seat 605 is installed on the translation mechanism 5, the lifting motor 601 is connected with the installation seat 605 through the vertical column 602, the linear bearing 608 is located in the vertical column 602, the sliding guide rod 606 is located in the vertical column 602 and is matched with the linear bearing 608, the sliding guide rod 606 is matched with the installation seat 605 through a sliding rail and a sliding chute 609, the lower end of the sliding guide rod 606 penetrates through the installation seat 605 and is connected with the suction mechanism 7, the upper end of the sliding guide rod 606 is connected with a screw nut 610, the screw 607 is connected with the lifting motor 601, and the screw nut 610 is matched with the screw 607; the upright post 602 is provided with a sliding groove 609, the position indication shaft II 604 is arranged on the sliding guide rod 606 and penetrates through the sliding groove 609, the optical coupling sensor II 603 is arranged on the upright post 602, and the optical coupling sensor II 603 is used for detecting the in-place information of the position indication shaft II 604.
Further, the mounting seat 605 is mounted on the sliding seat 506.
Thus, one end of the upright post 602 is connected with the sliding seat 506 through the mounting seat 605, the other end is connected with the lifting motor 601, when the lifting motor 601 rotates, the screw 607 is driven to rotate, so that the sliding guide rod 606 can move back and forth on the linear bearing 608 arranged in the upright post 602, and the sliding guide rod 606 can ascend or descend, thereby realizing the purpose of moving the suction mechanism 7 up and down; and whether the sliding guide rod 606 is lifted to the place or not is judged according to the information of the marking shaft II detected by the optical coupling sensor II 603.
Wherein, suction means 7 includes vacuum chuck 701 and vacuum chuck connecting plate 702, vacuum chuck 701 installs on vacuum chuck connecting plate 702, vacuum chuck connecting plate 702 is connected with elevating system 6.
Further, the vacuum chuck connection plate 702 is connected to the sliding guide 606.
In this way, the suction of the reagent disk 18 and the transfer of the reagent disk 18 are originally performed by the vacuum connected by the vacuum chuck 701.
The constant temperature assembly comprises an inner ring heating assembly, an outer ring heating assembly and an upper portion heating assembly, the inner ring heating assembly is mounted on the surface of the inner ring turntable assembly 3, the outer ring heating assembly is mounted on the surface of the outer ring turntable assembly 2, and the upper portion heating assembly and the disc transfer assembly 4 are arranged on the disc transfer assembly 4.
Thus, the purpose of temperature control is realized through the inner ring heating assembly, the outer ring heating assembly and the upper heating assembly, so that the inside of the shell 1 is kept in a constant temperature state.
The inner ring heating assembly comprises an inner heating fixing plate 801, an inner ring heating film and an inner ring heating plate 802, wherein the upper surface and the lower surface of the inner ring heating film are respectively connected with the inner ring heating plate 802 and the inner heating fixing plate 801 to form a whole, and the surface of the inner ring turntable assembly is covered with the whole;
the upper heating assembly comprises upper heating foam 901, an upper heating plate 902 and an upper heating film 903, the side surface of the upper heating film 903 is respectively connected with the upper heating foam 901 and the upper heating plate 902, and the upper heating plate 902 is connected with the disc transfer assembly 4 through a shock absorption column 14;
the outer ring heating assembly comprises an outer heating plate 1001, an outer ring heating film 1002, heating cavity upper foam 1003 and a heat preservation shell 1004, the outer ring heating film 1002 is arranged on the outer heating plate 1001, the heat preservation shell 1004 coats the upper part of the outer ring turntable rotating assembly to form a heat preservation cavity, the heating cavity upper foam 1003 is arranged on the heat preservation shell 1004, a heating cavity upper cover plate 1006 is arranged between the heating cavity upper foam 1003 and the heat preservation shell 1004, a notch 1005 for the disc transfer assembly 4 to pass is arranged on the side surface of the heat preservation shell 1004, and a sliding groove 12 is arranged on the upper heating plate 902, the upper heating foam 901 and the upper heating film 903.
Therefore, the purpose of constant temperature inside can be realized, and the smooth detection is ensured.
Further preferably, a bin door is arranged at the notch 1005, and the bin door can open or close the notch 1005; in this way, internal heat dissipation can be avoided.
Further optimize, sliding tray 12 department is equipped with brush sealing strip 13, can seal sliding tray 12 through the setting of brush sealing strip 13, can avoid the heat to scatter and disappear, simultaneously, still can not exert an influence to the motion of dish transfer unit 4.
The in-and-out bin assembly 15 comprises a guide rail seat 1501, a bracket 1502, a sensor 1503, a driving device and an identification device 1505, wherein the bracket 1502 is installed on the guide rail seat 1501 in a sliding mode, an inclined plane 1506 is arranged on the guide rail seat 1501, a tray fixing hole 1507 and a tray discharging hole 1504 are arranged on the bracket 1502, the driving device can drive the bracket 1502 to move on the guide rail seat 1501, the sensor 1503 is installed on the guide rail seat 1501, a detection hole capable of being detected by the sensor 1503 is arranged on the bracket 1502, the identification device 1505 is installed on a tray transfer group, the identification device 1505 is used for identifying the reagent trays 18 to be detected, and the sensor 1503 is connected with the driving device.
Wherein, said identification means 1505 is mounted on the upper cover main bracket 401.
In this way, the identification device 1505 identifies the information on the reagent disk 18 to obtain the information of the reagent disk 18, such as the information of the item to be detected, the information of the centrifugal preparation rotation speed, etc., the preparation station 17 prepares the reagent disk for centrifugation according to the obtained information, adjusts the centrifugation time and the rotation speed, and the detection device 20 can also perform targeted detection on the reagent disk 18 according to the information; the driving bracket 1502 is driven by the driving device to move on the guide rail, the reagent disk 18 is put into a warehouse, the sensor 1503 is used for detecting the position information of the bracket 1502, the reagent disk 18 is placed at the disk fixing hole 1507 and enters the shell 1, the reagent disk is transferred to the inside by the disk transfer assembly 4, when the reagent disk 18 with the internal detection completed needs to be transferred out, the disk outlet hole 1504 is aligned to the inclined plane 1506, the reagent disk 18 directly passes through the disk outlet hole 1504 and then falls to the lower surface, and slides out of the inclined plane 1506.
Wherein, the driving device comprises a motor 1508, a gear 1509 and a rack 1510, the motor 1508 is mounted on the guide rail base 1501, the gear 1509 is connected with the motor 1508, the gear 1509 is meshed with the rack 1510, and the motor 1508 is connected with the sensor 1503.
Thus, the gear 1509 is driven by the motor 1508 to rotate, thereby driving the rack 1510 to move, and driving the carriage 1502.
The bin gate comprises a rack C1101, a gear C1102, a motor C1103, a bin gate plate 1104, a guide rod 1105 and a guide seat 1109, wherein the guide seat 1109 is installed on a guide rail seat 1501, the guide rod 1105 is installed on the guide rail seat 1501 through the guide seat 1109, the rack C1101 is connected with the bin gate plate 1104, the bin gate plate 1104 is installed on the guide rod 1105 in a sliding mode, the motor C1103 is installed on the guide rail seat 1501, the gear C1102 is meshed with the rack C1101, the bin gate plate 1104 is connected with an induction plate 1106, the guide rail seat 1501 is provided with an upper detection sensor 1107 and a lower detection sensor 1108, the upper detection sensor 1107 and the lower detection sensor 1108 are connected with the motor C1103, and position information of the induction plate 1106 can be detected.
In this way, the position of the door plate 1104 is determined by detecting the position of the sensing plate 1106 through the up-down sensor 1503, the guide bar 1105 mainly plays a role in guiding, so that the door plate 1104 can better move, the motor C1103 drives the gear C1102 to rotate, the gear C1102 rotates to drive the rack C1101 to move up and down, the door plate 1104 further moves up and down under the guiding effect of the guide bar 1105, and then the door plate 1104 is opened and closed.
Wherein, detection station 16 and preparation station 17 all include rotating electrical machines 1601, tray 1602 and ejector pin 1603 subassembly, tray 1602 links to each other with rotating electrical machines 1601, ejector pin 1603 subassembly can pass rotating electrical machines 1601, ejector pin 1603 subassembly can lock reagent dish 18, installs two climbing mechanism in casing 1, and two climbing mechanism are located outer loop carousel subassembly 2 and inner ring carousel subassembly 3 below respectively, and detection station 16 and preparation station 17 rotate to behind the climbing mechanism top, and climbing mechanism can push up the ejector pin subassembly, and the locking state with reagent dish 18 after the ejector pin subassembly rises is relieved.
In this way, the rotating motor 1601 drives the tray 1602 to rotate, and then drives the reagent tray 18 to rotate, locks the reagent tray 18 through the push rod 1603 assembly, and releases the locking state of the push rod 1603 assembly through the jacking mechanism.
Wherein, the said knockout pin 1603 assembly includes knockout pin 1603, sliding bush 1604, big spring 1605, slide block 1606, sliding core 1607 and little spring 1608, the said sliding bush 1604 one end is big and one end is small, the inside of sliding bush 1604 presents the hollow structure, this hollow structure presents one end big and one end small state, the said knockout pin 1603 is hollow, after knockout pin 1603 connects with small end of sliding bush 1604, form a step inside the sliding bush 1604, the said slide block 1606 is installed in the big end of sliding bush 1604, the said sliding core 1607 is installed in knockout pin 1603 and with the same axle center of sliding bush 1604 and slide block 1606, the said little spring 1608 locates in sliding bush 1604 and overlaps on the sliding core 1607, one end of the little spring 1608 connects with end of knockout pin 1603, one end connects with end of slide block 1606, there are two spacing holes 1609 on the end of knockout pin 1603, there are spacing troughs 1610 on the position of said spacing hole 1607 and said spacing hole 1609, there are spacing balls 1611 in the said spacing hole 1609, spacing ball 1611 connects with sliding core, the big spring 1605 is sleeved on the push rod 1603 and the sliding sleeve 1604.
In practice, the upper end of the large spring 1605 will be in contact with the rotary electric machine 1601.
Wherein the jacking mechanism comprises a cam bracket 1901, a cam 1902, a jacking motor 1903, a fixed shaft 1904, a torsion spring 1905, a first ejector arm 1906 and a second ejector arm 1907, the motor 1508 is mounted on a cam bracket 1901, the cam 1902 is connected to a jacking motor 1903, the fixed shaft 1904 is fixedly installed on the cam bracket 1901, the first and second jack arms 1906 and 1907 are installed coaxially with the fixed shaft 1904, and the first and second push rod arms 1906 and 1907 can rotate around the axis line of the fixed shaft 1904, the torsion spring 1905 is mounted on the fixed shaft 1904, and the two torsion arms of the torsion spring 1905 are connected with the first push rod arm 1906 and the second push rod arm 1907, an arc notch 1908 is arranged on the cam 1902, the arc notch 1908 divides the cam 1902 into two different cam surfaces 1909, and the first and second plunger arms 1906, 1907 press against the cam surfaces 1909, respectively, under the action of the torsion spring 1905.
The cam 1902 is driven to rotate by the rotation of the jacking motor 1903, under the action of the torsion spring 1905, the first ejector arm 1906 and the second ejector arm 1907 respectively press on two cam surfaces 1909 on the cam 1902 under the action of the torsion spring 1905, when the cam 1902 rotates, because one of the cam surfaces 1909 is formed by the arc notch 1908, in this way, the other cam surface 1909 can push the sliding sleeve 1604 upwards, that is: the first ejector arm 1906 contacts with the sliding sleeve 1604 to push the sliding sleeve 1604 upwards, so that under the action of the elastic sheet, the limiting ball 1611 is pulled, the limiting ball 1611 enters the limiting hole 1609, and the locked reagent disk 18 is released; at this time, the cam surface 1909 formed by the arc notch 1908 reaches the highest point, and the second plunger arm 1907 pushes up the slide core 1607, so that the slide core 1607 and the slide sleeve 1604 move upward to eject the reagent disk 18, and wait for the disk transfer unit 4 to transfer the reagent disk 18.
It should be noted that the ejector rod 1603 assembly and the jacking mechanism may not be used, and the cooperation of the ejector rod 1603 assembly and the jacking mechanism mainly achieves the purpose of locking and jacking the reagent disk 18; in practical use, after the tray 1602 is connected to the rotary motor 1601, a protrusion is arranged on the tray 1602, a groove is arranged at the bottom of the reagent disk 18, and the reagent disk 18 is limited by the protrusion and the groove in a matching manner; alternatively, the reagent disk 18 placed on the tray 1602 may be clamped by any clamping device known in the art.
The detection process is as follows:
s1: starting the analyzer, enabling the reagent disk 18 to be detected to enter the analyzer through the in-out bin assembly 15, identifying the reagent disk 18, and acquiring information to be detected of the reagent disk 18;
s2: the disk transfer component 4 transfers the reagent disk 18 to the preparation station 17 on the outer ring turntable component 2 to perform a centrifugal preparation process, the preparation station 17 determines the preparation time and the rotating speed of the preparation station 17 according to the acquired information to be detected, and after the previous reagent disk 18 to be detected is placed, the outer ring turntable component 2 rotates to enable the idle preparation station 17 to rotate to the moving path of the disk transfer component 4 to enter a disk receiving state; the disk transfer component 4 transfers the subsequent reagent disk 18 to the idle preparation station 17 in a return stroke, and the steps are circulated to finish the preparation process before the detection of the reagent disk 18, wherein one preparation station 17 needs to be kept in an idle state;
s3: firstly, a to-be-detected reagent disc 18 entering a preparation station 17 completes a preparation process, the to-be-detected reagent disc is transferred to a detection station 16 on an inner ring turntable assembly 3 through a disc transfer assembly 4, the detection station 16 drives the reagent disc 18 to rotate, the inner ring turntable assembly 3 drives the detection station 16 to rotate to a detection device 20 for detection, and an idle detection station 16 enters a to-be-connected disc state;
s4: the disk transfer component 4 transfers a new reagent disk 18 to the idle preparation station 17 in a return trip, or transfers the reagent disk 18 which has completed the preparation process to the idle detection station 16 to wait for detection;
s5: after the detection of the first detected reagent disk 18 is finished, the inner ring turntable assembly 3 rotates, a new reagent disk 18 is rotated to the detection device 20 for detection, the detected reagent disk 18 rotates to the position below the path of the disk transfer assembly 4, and the analyzer is dispatched out through the disk transfer assembly 4, so that the detection of the reagent disk 18 is finished;
s5: after the detected reagent tray 18 is transferred out of the analyzer, the tray transfer component 4 transfers a new reagent tray 18 to the preparation station 17 in an idle state, transfers the reagent tray 18 which finishes the preparation process to the idle detection station 16, so that the reagent tray 18 enters a state to be detected, and simultaneously, the fully loaded preparation station 17 is idled to one to enter a state of a reagent tray to be received; in this way, continuous testing of the reagent disk 18 is achieved.
In S2, the in-out magazine assembly 15 identifies the reagent disk 18 by an identification device 1505, the identification device 1505 being a bar code identification device or a two-dimensional code identification device.
The information to be detected comprises sample information, information to be detected of the sample, sample detection time, sample centrifugal rotating speed information and sample centrifugal direction information.
Like this, when a plurality of reagent dishes 18 need to be detected, put reagent dish 18 into business turn over storehouse subassembly 15 department in proper order, under the effect of dish transfer subassembly 4, transfer reagent dish 18 to preparation station 17 on outer ring carousel subassembly 2 in proper order and carry out the preparation before detecting, preparation station 17 rotates and drives reagent dish 18 and rotate and carry out centrifugal preparation to it, after preceding reagent dish 18 is placed, outer ring carousel subassembly 2 rotates, make idle preparation station rotatory to the position, be located the removal route below of dish transfer subassembly 4 promptly, dish transfer subassembly 4 return stroke transfers subsequent reagent dish 18 to this preparation station 17 department, it needs to notice, it is in idle state to guarantee to have a preparation station 17, namely: one of the preparation stations 17 does not house a reagent disk 18.
The reagent disk 18 which enters the preparation station 17 firstly completes the preparation process, the outer ring turntable assembly 2 rotates the preparation station 17 to the position below the path of the disk transfer assembly 4, the reagent disk 18 which completes the preparation process is transferred to the detection station 16 on the inner ring turntable assembly 3 under the action of the disk transfer assembly 4, and the inner ring turntable assembly 3 rotates, so that the detection station 16 rotates to the position of the detection device 20 with the reagent disk 18 to carry out detection.
Due to the short time for transferring the reagent disk 18 by the disk transfer unit 4, after the reagent disk 18 is ready to be prepared, the disk transfer unit 4 places the reagent disk 18 ready to be prepared in another preparation station 17, and at this time, the disk transfer unit 4 transfers the reagent disk 18 ready to be prepared to the spare preparation station 17.
After the reagent disk 18 which is firstly detected is detected, the inner ring turntable component 3 rotates 180 degrees, the two detection stations 16 are changed, the disk transfer component 4 transfers the detected reagent disk 18 to the in-out bin component 15 for discharging, transfers a new reagent disk 18 to the idle preparation station 17, and transfers the reagent disk 18 which subsequently completes the preparation process to the idle detection station 16 after the reagent disk 18 is placed.
It should be noted that, the reagent disk 18 on the preparation station 17 is firstly entered, the detection is firstly entered into the detection station 16, the reagent disk 18 which is firstly detected is firstly discharged out of the housing 1, the reagent disk 18 is continuously detected in this way, the reagent disk 18 which completes the preparation process is waiting for detection while the reagent disk 18 on the preparation station 17 is detected, and meanwhile, the reagent disk 18 on the preparation station 17 is centrifugally prepared, so that the continuous detection of the reagent disk 18 is realized, and the detection efficiency of the reagent disk 18 is improved.
Therefore, the synchronous operation of the detection station 16 and the preparation station 17 can be realized, the detection process can be continuously performed, the detection process and the preparation process can be simultaneously performed, the detection continuity is good, and the detection efficiency can be greatly improved; simultaneously, the preparation station 17 on 2 rows of outer loop carousel subassembly is the annular and distributes, can effectually reduce the occupation of preparing the process, and then makes its inside setting more reasonable, and then reduces the volume of whole analysis appearance.
Claims (9)
1. A full-automatic biochemical analysis method comprises the following steps: enabling the reagent tray to enter an analyzer, detecting the reagent tray after the reagent tray is subjected to a centrifugal preparation process, and moving the reagent tray after detection out of the analyzer;
the method is characterized in that:
the analyzer comprises an outer ring turntable assembly, an inner ring turntable assembly, a disc transfer assembly, a preparation station, a detection station, an in-out bin assembly, a constant temperature assembly and a detection device which are arranged in a shell, the preparation stations are provided with a plurality of detection stations which are distributed on the outer ring rotating disc component in an annular mode, the detection stations are provided with at least two detection stations which are distributed on the inner ring rotating disc component in an evenly distributed mode, the preparation station and the detection station can rotate, the inner ring turntable assembly is positioned in the middle of the outer ring turntable assembly, the outer ring turntable assembly can drive the preparation station to rotate, the inner ring turntable assembly can drive the detection station to rotate, the in-out bin assembly is used for delivering and feeding the reagent tray, the detection device is used for detecting the reagent tray, the constant temperature component is used for keeping the interior constant temperature, and the disk transfer component is used for transferring the reagent disk among the in-out bin component, the preparation station and the detection station;
the steps are as follows:
s1: starting the analyzer, enabling the reagent disk to be detected to enter the analyzer through the in-out bin assembly, identifying the reagent disk, and acquiring to-be-detected information of the reagent disk to be detected;
s2: the reagent disk is transferred to a preparation station on the outer ring turntable assembly by the disk transfer assembly to carry out a centrifugal preparation process, the preparation station determines the preparation time and the rotation speed of the preparation station according to the acquired information to be detected, and after the previous reagent disk to be detected is placed, the outer ring turntable assembly rotates to enable the idle preparation station to rotate to the moving path of the disk transfer assembly and enter a disk receiving state; the disc transfer assembly transfers the subsequent reagent disc to an idle preparation station in a return stroke, and the steps are circulated in such a way to finish the preparation process before the detection of the reagent disc, wherein one preparation station needs to be kept in an idle state;
s3: firstly, a to-be-detected reagent disk entering a preparation station firstly completes the preparation process, the to-be-detected reagent disk is transferred to a detection station on an inner ring turntable assembly through a disk transfer assembly, the detection station drives the reagent disk to rotate, the inner ring turntable assembly drives the detection station to rotate to a detection device for detection, and an idle detection station enters a to-be-connected disk state;
s4: the tray transfer assembly transfers a new reagent tray to an idle preparation station in a return stroke, or transfers the reagent tray which has finished the preparation process to an idle detection station to wait for detection;
s5: after the detection of the first detected reagent disk is finished, the inner ring turntable assembly rotates, a new reagent disk is rotated to the detection device for detection, the detected reagent disk rotates to the position below the path of the disk transfer assembly, and is dispatched out of the analyzer through the disk transfer assembly, and the detection of the reagent disk is finished;
s5: after the detected reagent tray is transferred out of the analyzer, a tray transfer assembly transfers a new reagent tray to a preparation station in an idle state, transfers the reagent tray which finishes the preparation process to an idle detection station, and enables the reagent tray to enter a state to be detected, and meanwhile, enables the fully loaded preparation station to be idle to be one so as to enable the reagent tray to enter a state of a reagent tray to be received; thus, continuous detection of the reagent tray is realized.
2. The method according to claim 1, wherein the biochemical analysis comprises: in S2, the in-out bin assembly identifies the reagent tray through an identification device, which is a bar-shaped identification device or a two-dimensional code identification device.
3. The method according to claim 1, wherein the biochemical analysis comprises: the information to be detected comprises sample information, information to be detected of the sample, sample detection time, sample centrifugal rotating speed information and sample centrifugal direction information.
4. The method according to claim 1, wherein the biochemical analysis comprises: the outer ring turntable assembly comprises an outer ring fixing support, a rotary disc and a driving device I, the outer ring fixing support is installed on a bottom plate arranged at the bottom in the analyzer shell, the rotary disc is installed on the outer ring fixing support, the driving device I can drive the rotary disc to rotate on the outer ring fixing support, and the preparation station is arranged on the rotary disc.
5. The method according to claim 4, wherein the biochemical analysis comprises: a plurality of eccentric roller shafts are uniformly distributed on the outer ring fixing support, roller bodies are connected to the eccentric roller shafts through bearings, recesses are formed in the side faces of the roller bodies, and the edges of the rotary discs can be matched with the recesses; the outer ring fixing support is connected with the bottom plate through a support column I, and a shock pad is arranged between the outer ring fixing support and the support column I.
6. The method according to claim 5, wherein the biochemical analysis comprises: drive arrangement I includes motor I, gear I and sector I, I installation of motor is on the outer ring fixed bolster, gear I links to each other with motor I, sector I is installed in the gyration dish below, gear I and I intermeshing of sector.
7. The method according to claim 1, wherein the biochemical analysis comprises: inner ring carousel subassembly includes base member seat, interior gyration dish, center pin and drive arrangement II, detection device installs on the base member seat, base member seat fixed mounting is on the bottom plate of bottom setting in the analysis appearance casing, the center pin passes through the bearing and vertically installs on the base member seat, interior gyration dish is fixed on the center pin, including the detection station sets up on the gyration dish, drive arrangement II can drive interior gyration dish and rotate.
8. The method according to claim 7, wherein the biochemical analysis comprises: the driving device II comprises a motor II, a gear II and a sector II, the motor II is installed on the bottom plate through an inner ring motor installation piece, the gear II is connected with the motor II, the sector II is installed below the rotary disc, and the sector II is meshed with the gear II.
9. The method according to claim 7, wherein the biochemical analysis comprises: the tray transferring assembly comprises an upper cover main support, a lower cover main support, a spring support rod, a lifting mechanism, an absorbing mechanism and a translation mechanism, the lower cover main support is connected with an outer ring turntable assembly, the upper cover main support is hinged to the lower cover main support, the spring support rod is connected between the upper cover main support and the lower cover main support, the translation mechanism is installed on the upper cover main support, the lifting mechanism is installed on the translation mechanism, the absorbing mechanism is installed on the lifting mechanism, the translation mechanism is used for driving the lifting mechanism and the absorbing mechanism to translate towards the direction of the outer ring turntable assembly, the inner ring turntable assembly and the warehouse inlet and outlet assembly, the lifting mechanism is used for driving the absorbing mechanism to vertically move, and the absorbing mechanism is used for tightly absorbing or loosening the reagent tray.
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000060362A9 (en) * | 1999-04-08 | 2002-12-12 | Chung Chang Young | Apparatus for fast preparation and analysis of nucleic acids |
| CN104657400A (en) * | 2013-11-19 | 2015-05-27 | 光宝科技股份有限公司 | Centrifugal analysis system and analysis method thereof |
| CN104793003A (en) * | 2015-04-02 | 2015-07-22 | 江苏克莱斯克生物技术有限公司 | Blood group serology detection method and automatic detection system for realizing method |
| WO2015197080A1 (en) * | 2014-06-27 | 2015-12-30 | H.C. Smede Aps | A centrifuge, and a method of operating the centrifuge |
| CN207056812U (en) * | 2017-07-25 | 2018-03-02 | 烟台德迈生物科技有限公司 | A kind of microwell plate centrifugal device |
| CN209102734U (en) * | 2018-09-29 | 2019-07-12 | 厦门大学 | A kind of small portable detection information collection device |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104386629B (en) * | 2014-09-22 | 2016-06-29 | 深圳市奥特库贝科技有限公司 | A kind of novel agent bottle automatically opening and closing mechanism |
| CN106290942A (en) * | 2016-08-31 | 2017-01-04 | 成都恩普生医疗科技有限公司 | A kind of Full-automatic chemiluminescence immunoassay analysis meter |
| CN207623360U (en) * | 2017-12-07 | 2018-07-17 | 北京京仪博电光学技术有限责任公司 | Analysis of protein equipment |
-
2019
- 2019-07-31 CN CN201910698829.6A patent/CN110261635B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000060362A9 (en) * | 1999-04-08 | 2002-12-12 | Chung Chang Young | Apparatus for fast preparation and analysis of nucleic acids |
| CN104657400A (en) * | 2013-11-19 | 2015-05-27 | 光宝科技股份有限公司 | Centrifugal analysis system and analysis method thereof |
| WO2015197080A1 (en) * | 2014-06-27 | 2015-12-30 | H.C. Smede Aps | A centrifuge, and a method of operating the centrifuge |
| CN104793003A (en) * | 2015-04-02 | 2015-07-22 | 江苏克莱斯克生物技术有限公司 | Blood group serology detection method and automatic detection system for realizing method |
| CN207056812U (en) * | 2017-07-25 | 2018-03-02 | 烟台德迈生物科技有限公司 | A kind of microwell plate centrifugal device |
| CN209102734U (en) * | 2018-09-29 | 2019-07-12 | 厦门大学 | A kind of small portable detection information collection device |
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Address after: No.1, 1st floor, building 1, No.333 Hezuo Road, high tech Zone, Chengdu, Sichuan 610000 Patentee after: Chengdu Smart Technology Co.,Ltd. Country or region after: China Address before: No.1, 1st floor, building 1, No.333 Hezuo Road, high tech Zone, Chengdu, Sichuan 610000 Patentee before: CHENGDU SEAMATY TECHNOLOGY Co.,Ltd. Country or region before: China |