CN110151929A - A kind of method and application of the health preserving tea preparation with effect of lowering blood sugar - Google Patents

A kind of method and application of the health preserving tea preparation with effect of lowering blood sugar Download PDF

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Publication number
CN110151929A
CN110151929A CN201910574741.3A CN201910574741A CN110151929A CN 110151929 A CN110151929 A CN 110151929A CN 201910574741 A CN201910574741 A CN 201910574741A CN 110151929 A CN110151929 A CN 110151929A
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polygonati officinalis
radix polygonati
mulberry leaf
lophatherum gracile
sanchi flower
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江雪平
吴娜
刘军
柳红娥
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Yibai (wuhan) Health Technology Co Ltd
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Yibai (wuhan) Health Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23FCOFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00Tea; Tea substitutes; Preparations thereof
    • A23F3/34Tea substitutes, e.g. matè; Extracts or infusions thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/49Fagaceae (Beech family), e.g. oak or chestnut
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Diabetes (AREA)
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Abstract

The present invention relates to diabetes technical field, the method for especially a kind of health preserving tea preparation with effect of lowering blood sugar includes the following steps: that raw material are picked: it is spare to pick fresh multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf respectively;Crush for the first time: pulverization process carried out to multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf respectively with pulverizer, and smashed multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf size be 0.5-1 centimetres.The present invention produces medicinal tea using multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis, mulberry leaf, dry Hubei Chinese flowering crabapple leaf and dry vine tea as raw material, and these raw materials for production are the raw material and new resource food raw material of common integration of drinking and medicinal herbs, substantially it is free from side effects, along with other no auxiliary raw materials, edible more safety and conveniently, the concentration of insulin in type 2 diabetes patient's blood plasma can be effectively adjusted, improves tissue to the susceptibility of insulin.

Description

A kind of method and application of the health preserving tea preparation with effect of lowering blood sugar
Technical field
The present invention relates to diabetes technical field more particularly to a kind of methods of the health preserving tea preparation with effect of lowering blood sugar With application.
Background technique
The diabetes prevalence of Chinese is 9.7% at present, and the diabetic made a definite diagnosis has nearly 100,000,000, and people at highest risk is close 1.5 hundred million.Human gene structural research shows that the pathogenesis of diabetes is pancreas islet genetic mutation, and insulin microcirculation hinders Hinder, lead to blood glucose rise, sugar tolerance reduces.The oral hypoglycaemic product to circulate on the market at present is roughly divided into three classes: promoting pancreas islet Once quick dose of plain secrete pharmaceutical, insulin, the drug for reducing carbohydrate absorption.Medication effect is obvious, but single effect, It is palliative, it cannot eradicate substantially, and there are also side effects, for example Nausea and vomiting, abdomen occur after taking hypoglycemic drug The adverse reactions such as swollen, indigestion, sulfamido antidiabetic drug there is also Hypoglycemic symptoms, and drug is also not suitable for crowd, such as Cardiac, pregnant woman, wet nurse, intestines problem patient, the infull person of renal function etc. are not applicable.Antihypelipidemic foodstuff one on the market As, general single effect in the majority with capsule class health care product, lead to that effect is unobvious or the period is longer, capsule itself is to human body Side effect is larger.Traditional Chinese medicine compound preparation is troublesome in poeration, not portable, and long-term drinking is affected to digestive system.
Summary of the invention
The purpose of the present invention is to solve disadvantages existing in the prior art, and the one kind proposed has effect of lowering blood sugar Health preserving tea preparation method and application.
To achieve the goals above, present invention employs following technical solutions:
A kind of method for designing health preserving tea preparation with effect of lowering blood sugar, includes the following steps:
S1, raw material picking: it is spare that fresh multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf are picked respectively;
S2, it crushes: multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf being crushed respectively for the first time with pulverizer Processing, and smashed multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf size be 0.5-1 centimetres;
S3, immersion: by smashed multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf according to the ratio of 1:1:1:1:1 Example is added in 10 times of purified water, is then impregnated 30 minutes, is finally all poured into liquid in container A;
S4, extraction: the pressure of 0.06Mpa is added in container A, and continues 2 hours;
S5, it filters for the first time: processing being filtered to the liquid in container A with filter, respectively obtains filtrate A and filter residue A;
S6, filter residue A reprocessing: will be added 8 times of own wt of purified water in filter residue A, impregnate 5 minutes after stirring, then Liquid is encased in container B, the pressure of 0.06Mpa is added in container B, and continues 1.5 hours;
S7, it filters for second: processing being filtered to the liquid in container B with filter, respectively obtains liquor B and filter residue B;
S8, filtrate processing: the liquor B in the filtrate A and step S7 in step S5 is uniformly mixed, and by mixed liquid Body is concentrated under vacuum conditions, finally obtains medicinal extract;
S9, it crushes for second: pulverization process being carried out to medicinal extract, dry Hubei Chinese flowering crabapple leaf and dry vine tea respectively with pulverizer, and And require smashed medicinal extract, dry Hubei Chinese flowering crabapple leaf and dry vine tea can be by the sieve of 10 mesh;
S10, mixing, granulation: smashed medicinal extract, dry Hubei Chinese flowering crabapple leaf and dry vine tea being uniformly mixed, whole grain, drying, Granule is made;
S11, packing, packaging: granule is dispensed, packaging operation.
Preferably, in step sl, fresh multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and the mulberry leaf by picking back It is cleaned respectively with water, and multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and the mulberry leaf after cleaning is drained away the water.
Preferably, multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf are cleaned three times respectively with water, it is preceding to clean twice It is cleaned with clear water, is cleaned for the last time with purified water.
Preferably, preceding cleaning twice is rinsed 20 minutes by the way of rinsing, and last time cleaning is using the side impregnated Formula is impregnated 5 minutes.
Preferably, in step s3, it before immersion, is stirred with clean stirring rod.
The present invention also proposes that a kind of health preserving tea with effect of lowering blood sugar is treating the application in diabetes.
Preferably, the diabetes are type-2 diabetes mellitus.
The method and application of a kind of health preserving tea preparation with effect of lowering blood sugar proposed by the present invention, beneficial effect are: The present invention is produced using multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis, mulberry leaf, dry Hubei Chinese flowering crabapple leaf and dry vine tea as raw material Medicinal tea, and these raw materials for production are the raw material and new resource food raw material of common integration of drinking and medicinal herbs, are free from side effects substantially, Along with other auxiliary raw materials, more safety and conveniently is eaten, type 2 diabetes patient's blood can be effectively adjusted The concentration of insulin in slurry improves tissue to the susceptibility of insulin.
Specific embodiment
It is next combined with specific embodiments below that the present invention will be further described.
A method of the health preserving tea preparation with effect of lowering blood sugar includes the following steps:
S1, raw material picking: it is spare that fresh multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf are picked respectively;It will Fresh multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and the mulberry leaf of picking back are cleaned with water respectively, and will be after cleaning Multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf drain away the water, with water respectively to multiple-ear rock Ke, sanchi flower, lophatherum gracile, Three times, preceding cleaning twice is cleaned with clear water, is cleaned for the last time with purified water for radix polygonati officinalis and mulberry leaf cleaning, preceding clear twice It washes by the way of rinsing, rinses 20 minutes, last time cleaning is impregnated 5 minutes by the way of impregnating;
Flavonoid content is up to 14.6%-22.2% in multiple-ear rock Ke, wherein dihydrochalcone-phloridzin content 12.6%, Hubei Chinese flowering crabapple leaf kind is rich in apple polyphenol, phloridzin, and decaffeinated, it has been investigated that phloridzin is to diabetes And its complication has unique preventive and therapeutic effect, phloridzin exclusively, competitively inhibits SGLT1 and SGLT2 to glucose molecule Transport, reduce on an empty stomach and level of postprandial blood sugar, but hypoglycemia side effect do not occur, while can to restore its insulin quick for phloridzin Insulin resistance is eliminated or mitigated to perception, and a variety of flavonoid monomer compounds such as phloridzin have enhancing tissue oxidation resistance, Free radical is removed, anti-lipid peroxidation protects cell membrane obviously to repair while being effectively reduced blood glucose from the effect of damage The susceptibility of multiple insulin;Cupreol, daucosterol, notoginsenoside, gypenoside-LX, ginseng soap are rich in sanchi flower The ingredients such as glycosides have effects that clearing heat and detoxicating, decompression, lipid-loweringing, weight-reducing, oxidation resistant;Contain arundoin, print cogongrass in lophatherum gracile Element, taraxerol, freidelin have effects that clearing heat and detoxicating, relieving restlessness is quenched the thirst;Fragrant solomonseal rhizome polyoses in radix polygonati officinalis have anti-grease matter mistake Oxidation can obviously improve intracorporal glucose -lipid metabolism disorder of leting people, significant to reduce glucose and triglyceride level;Mulberry leaf In 1-Deoxynojirimycin invertase in human body, maltose, glucuroide, amylase etc. can be inhibited to resolve into starch The process of sugar can effectively inhibit the conversion of sugar;
S2, it crushes: multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf being crushed respectively for the first time with pulverizer Processing, and smashed multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf size be 0.5-1 centimetres;
S3, immersion: by smashed multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf according to the ratio of 1:1:1:1:1 Example is added in 10 times of purified water, is then impregnated 30 minutes, is finally all poured into liquid in container A;Before immersion, with dry Net stirring rod is stirred;
S4, extraction: the pressure of 0.06Mpa is added in container A, and continues 2 hours;In the pressure action of 0.06Mpa Under, the precipitation of the substance in multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf can be accelerated, improve working efficiency;
S5, it filters for the first time: processing being filtered to the liquid in container A with filter, respectively obtains filtrate A and filter residue A;
S6, filter residue A reprocessing: will be added 8 times of own wt of purified water in filter residue A, impregnate 5 minutes after stirring, then Liquid is encased in container B, the pressure of 0.06Mpa is added in container B, and continues 1.5 hours;To filter residue A again into Row processing, is to guarantee that the substance in filter residue A is precipitated completely;
S7, it filters for second: processing being filtered to the liquid in container B with filter, respectively obtains liquor B and filter residue B;
S8, filtrate processing: the liquor B in the filtrate A and step S7 in step S5 is uniformly mixed, and by mixed liquid Body is concentrated under vacuum conditions, finally obtains medicinal extract;
S9, it crushes for second: pulverization process being carried out to medicinal extract, dry Hubei Chinese flowering crabapple leaf and dry vine tea respectively with pulverizer, and And require smashed medicinal extract, dry Hubei Chinese flowering crabapple leaf and dry vine tea can be by the sieve of 10 mesh;The flavonoids contained in vine tea Compound is able to suppress the aggregation of blood platelet, reduces plasma fibrinogen concentration, reduces red cell deformability, softens blood Pipe promotes histocyte strength to utilize blood glucose, activates pancreatic functions, thus the effect of playing viscous drop blood, decompression, hypoglycemic;
S10, mixing, granulation: smashed medicinal extract, dry Hubei Chinese flowering crabapple leaf and dry vine tea being uniformly mixed, whole grain, drying, Granule is made;
S11, packing, packaging: granule is dispensed, packaging operation.
The present invention is using multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis, mulberry leaf, dry Hubei Chinese flowering crabapple leaf and dry vine tea as original Material produces medicinal tea, and these raw materials for production are the raw material and new resource food raw material of common integration of drinking and medicinal herbs, are not had substantially There is side effect, along with without other auxiliary raw materials, eating more safety and conveniently.
A kind of health preserving tea with effect of lowering blood sugar prepared by the present invention is suitable for treatment diabetes, and is more suitable for sugar Urine disease is that the patient of type-2 diabetes mellitus takes.When in use, packed health preserving tea is brewed with boiled water, one bag every time, daily 2-3 It is secondary, it can be effectively reduced the blood sugar concentration after type 2 diabetes patient has meal, and after taking a period of time, II type glycosuria The concentration of insulin is adjusted in patient's blood plasma, and tissue makes moderate progress to the susceptibility of insulin.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (7)

1. a kind of method of the health preserving tea preparation with effect of lowering blood sugar, which comprises the steps of:
S1, raw material picking: it is spare that fresh multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf are picked respectively;
S2, it crushes: multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf being carried out at crushing respectively for the first time with pulverizer Reason, and smashed multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf size be 0.5-1 centimetres;
S3, immersion: smashed multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf are added according to the ratio of 1:1:1:1:1 Enter into 10 times of purified water, then impregnates 30 minutes, finally all pour into liquid in container A;
S4, extraction: the pressure of 0.06Mpa is added in container A, and continues 2 hours;
S5, it filters for the first time: processing being filtered to the liquid in container A with filter, respectively obtains filtrate A and filter residue A;
S6, filter residue A reprocessing: 8 times of own wt of purified water will be added in filter residue A, is impregnated 5 minutes after stirring, then by liquid Body is encased in container B, and the pressure of 0.06Mpa is added in container B, and continues 1.5 hours;
S7, it filters for second: processing being filtered to the liquid in container B with filter, respectively obtains liquor B and filter residue B;
S8, filtrate processing: the liquor B in the filtrate A and step S7 in step S5 is uniformly mixed, and mixed liquid is existed It is concentrated under vacuum condition, finally obtains medicinal extract;
S9, it crushes for second: pulverization process being carried out to medicinal extract, dry Hubei Chinese flowering crabapple leaf and dry vine tea respectively with pulverizer, and is wanted Ask smashed medicinal extract, dry Hubei Chinese flowering crabapple leaf and dry vine tea can be by the sieve of 10 mesh;
S10, mixing, granulation: smashed medicinal extract, dry Hubei Chinese flowering crabapple leaf and dry vine tea are uniformly mixed, whole grain, drying are made Granule;
S11, packing, packaging: granule is dispensed, packaging operation.
2. a kind of method of health preserving tea preparation with effect of lowering blood sugar according to claim 1, which is characterized in that in step In rapid S1, fresh multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and the mulberry leaf of picking back are cleaned with water respectively, and Multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf after cleaning are drained away the water.
3. a kind of method of health preserving tea preparation with effect of lowering blood sugar according to claim 2, which is characterized in that use water Respectively three times to the cleaning of multiple-ear rock Ke, sanchi flower, lophatherum gracile, radix polygonati officinalis and mulberry leaf, preceding cleaning twice is cleaned with clear water, finally Once cleaned with purified water.
4. a kind of method of health preserving tea preparation with effect of lowering blood sugar according to claim 3, which is characterized in that preceding two Secondary cleaning is rinsed 20 minutes by the way of rinsing, and last time cleaning is impregnated 5 minutes by the way of impregnating.
5. a kind of method of health preserving tea preparation with effect of lowering blood sugar according to claim 1, which is characterized in that in step In rapid S3, before immersion, it is stirred with clean stirring rod.
6. a kind of application of the health preserving tea with effect of lowering blood sugar according to claim 1 in treatment diabetes.
7. a kind of method of health preserving tea preparation with effect of lowering blood sugar according to claim 6, which is characterized in that described Diabetes are type-2 diabetes mellitus.
CN201910574741.3A 2019-06-28 2019-06-28 A kind of method and application of the health preserving tea preparation with effect of lowering blood sugar Pending CN110151929A (en)

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Publication number Priority date Publication date Assignee Title
CN114432388A (en) * 2022-02-24 2022-05-06 益倍(武汉)健康科技有限公司 Composition with effects of reducing blood sugar and blood fat, preparation method and application

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