CN110013519A - 一种治疗高血压的药物配方 - Google Patents
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Abstract
本发明公开了一种治疗高血压的药物配方，由以下成分组成，当归，白芍，川芎，熟地，黄芪，红花，桃仁，黄精，茯牛花，丹参，徐长卿，首乌，通草，甜菊叶；其特征在于，所述的治疗高血压的药物组合物包括原料重量份的当归5‑10份，白芍10‑20份，川芎2‑20份，熟地10‑15份，黄芪6‑9份，红花12‑15份，桃仁3‑6份，黄精6‑9份，茯牛花2‑5份，丹参20‑30份，徐长卿3‑10份，首乌2‑10份，通草3‑5份，甜菊叶3‑5份。本发明制备所得治疗高血压病的药物，能有效降低血压，收缩压比舒张压的降低程度更加明显，无毒副作用，长期服用也不会损伤脏器，药物依赖性较小，用药较安全。
Description
技术领域
本发明属于中药技术领域，具体涉及一种治疗高血压的药物配方。
背景技术
高血压是世界上中老年发病较为普遍，在世界有5.6亿患者，在中国也有1.6亿入，并以每年300万新发病人递增，是世界的难题之一，它不但死亡率高，制残率也很高，当一个病人被诊断为高血压，他就必须走上终身服药的痛苦之路，而且现在降压药停药即反跳，副作用大，长效类降压药，普奈洛尔，降压1-2周起效，3-4周才明显，副作用大，停药即可产生血压反跳，并出现嗜睡、头晕、失眠、低血压心动过缓等；速效降压药卡托普利口服15分钟起效，但只能持续4～6小时，副作用大，如低血压、干咳、过敏、血管与神经水肿，停药血压即反跳。过去单纯的中医药的降压药也存在停药即反跳的缺点。
高血压疾病是世界上中老年发病较为普遍的疾病，它治愈率低，死亡率高。长期以来，治疗高血压通常采用西药医治，如西药普奈洛尔，这种药能产生缓慢、持久的降压作用，用药1-2周起，3～4周降压明显，使收缩压下降15-20％；但卡托普利这种药只能持续4～6小时，必须每天服用，大多数患者必须终生用药，停药血压反弹。申请号为02159134.2的专利申请，是一种治疗心脑血管栓塞的药物，对心脑栓塞能起到溶栓的作用，它具有醒脑开窍，强心提神，预防血栓生成及溶解血栓的作用，它与潘生丁、心地安的作用一样，以上两种药临床常用在治疗心绞痛上是扩张血管的药物，这种药物能扩张血管，所以它具有降压作用，扩张血管是暂时性的，因此它的降压作用也是临时的，不能从根本上解决。如患心绞痛病人，病人会马上服用两粒扩张血管药物，使病情立即得到缓解一样，对彻底治愈冠心病还要做进一步治疗。当然对于高血压病也有许多中医治疗方法，中医理论将人体分为上身为阳，下身为阴，高血压疾病是肝阳上亢、肝风内动。高血压疾病患者上身阳盛，下身虚，随着体内湿气的增多，血压逐步升高，病人表现易怒、心烦、头晕、失眠、性功能低下或阳萎。现在用药主要是利尿药物达到暂时降压，但这样会使人身上阳更盛，下身阴更虚，使很多病人从I期发展到II或III期高血压病，无论是西医治疗还是中医治疗高血压，对高血压病人都必须长期依赖药物进行治疗，长期服用药物一方面会给身体带来较大的副作用，很有可能在治疗高血压的同时引发其它病因。其二是医治费用高，对于生活困难的家庭带来精神上和经济上双重压力。
发明内容
本发明的目的在于提供一种治疗高血压的药物配方，以解决上述背景技术中提出的问题。
为实现上述目的，本发明提供如下技术方案：一种治疗高血压的药物配方，由以下成分组成，当归，白芍，川芎，熟地，黄芪，红花，桃仁，黄精，茯牛花，丹参，徐长卿，首乌，通草，甜菊叶；所述的治疗高血压的药物组合物包括原料重量份的当归5-10份，白芍10-20份，川芎2-20份，熟地10-15份，黄芪6-9份，红花12-15份，桃仁3-6份，黄精6-9份，茯牛花2-5份，丹参20-30份，徐长卿3-10份，首乌2-10份，通草3-5份，甜菊叶3-5份。
进一步地，将各原料药粉碎过筛，按配方配比混合均匀得到目标物治疗高血压的药物组合物。
进一步地，所述的粉碎过筛是粉碎过100目筛。
进一步地，治疗高血压的药物组合物中加入药学上可接受的辅料制备的片剂、散剂、胶囊剂、颗粒剂和丸剂。
进一步地，治疗高血压的药物组合物在制备治疗高血压药物中的应用。
本发明制备所得治疗高血压病的药物，能有效降低血压，收缩压比舒张压的降低程度更加明显，无毒副作用，长期服用也不会损伤脏器，药物依赖性较小，用药较安全。
具体实施方式
下面将结合本发明实施例，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
本发明提供一种治疗高血压的药物配方，由以下成分组成，当归，白芍，川芎，熟地，黄芪，红花，桃仁，黄精，茯牛花，丹参，徐长卿，首乌，通草，甜菊叶；所述的治疗高血压的药物组合物包括原料重量份的当归5-10份，白芍10-20份，川芎2-20份，熟地10-15份，黄芪6-9份，红花12-15份，桃仁3-6份，黄精6-9份，茯牛花2-5份，丹参20-30份，徐长卿3-10份，首乌2-10份，通草3-5份，甜菊叶3-5份。
其中，将各原料药粉碎过筛，按配方配比混合均匀得到目标物治疗高血压的药物组合物。
其中，所述的粉碎过筛是粉碎过100目筛。
其中，治疗高血压的药物组合物中加入药学上可接受的辅料制备的片剂、散剂、胶囊剂、颗粒剂和丸剂。
观察本研究所门诊高血压患者共139例，随机分为治疗组80例，对照组59例，治疗组中男性38例，女性42例，年龄30岁以下48例，30～40岁15例，41～50岁9例，51岁～60岁5例，60岁以上3例。最大者71岁，最小者11岁，平均年龄42岁高压异常23例，对照组中，男性27例，女性32例，30岁以下37例，31～40岁11例，41～50岁6例，51～60岁3例，60岁以上2例。最大者69岁，最小者9岁，平均年龄39岁。
其中，治疗高血压的药物组合物在制备治疗高血压药物中的应用。
排除病例标准：
1、进行肾脏移植术后及行血液净化治疗者。
2、孕妇及哺乳期妇女。
3、过敏体质及多种药物过敏者。
4、合并严重肝脏及造血***，内分泌***等严重原发性疾病及精神病患者。5、年龄在9岁以下或71岁以上者。
6、未按规定用药，无法判断疗效或资料不全等影响疗效及安全性判断者。
结果：治疗组显效12例，有效51例，无效17例，治疗有效率79％。
对照组显效3例，有效29例，无效27例，总有效率54％。
治疗组与对照组总有效率统计学处理有显著性差异。
尽管已经示出和描述了本发明的实施例，对于本领域的普通技术人员而言，可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型，本发明的范围由所附权利要求及其等同物限定。
Claims (5)
1.一种治疗高血压的药物配方，由以下成分组成，当归，白芍，川芎，熟地，黄芪，红花，桃仁，黄精，茯牛花，丹参，徐长卿，首乌，通草，甜菊叶；其特征在于，所述的治疗高血压的药物组合物包括原料重量份的当归5-10份，白芍10-20份，川芎2-20份，熟地10-15份，黄芪6-9份，红花12-15份，桃仁3-6份，黄精6-9份，茯牛花2-5份，丹参20-30份，徐长卿3-10份，首乌2-10份，通草3-5份，甜菊叶3-5份。
2.根据权利要求1所述的一种治疗高血压的药物配方，其特征在于：将各原料药粉碎过筛，按配方配比混合均匀得到目标物治疗高血压的药物组合物。
3.根据权利要求1所述的一种治疗高血压的药物配方，其特征在于：所述的粉碎过筛是粉碎过100目筛。
4.根据权利要求1所述的一种治疗高血压的药物配方，其特征在于：治疗高血压的药物组合物中加入药学上可接受的辅料制备的片剂、散剂、胶囊剂、颗粒剂和丸剂。
5.根据权利要求1所述的一种治疗高血压的药物配方，其特征在于：治疗高血压的药物组合物在制备治疗高血压药物中的应用。
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