CN109745354A - A kind of dental ulcer treatment agent - Google Patents
A kind of dental ulcer treatment agent Download PDFInfo
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- CN109745354A CN109745354A CN201910242258.5A CN201910242258A CN109745354A CN 109745354 A CN109745354 A CN 109745354A CN 201910242258 A CN201910242258 A CN 201910242258A CN 109745354 A CN109745354 A CN 109745354A
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- extract
- treatment agent
- oil
- ulcer treatment
- dental ulcer
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Abstract
The invention belongs to dental care agent fields, specifically disclose a kind of dental ulcer treatment agent, ratio includes: propylene glycol 1-3% by weight, lauryl sodium sulfate 2-5%, cold extraction resina liquidamberis medicinal extract 1-3%, thickener 1-2%, licorice 1-2%, calendula extract 1-2%, Myrrha extract 1-2%, buffer 1-2%, Olibanum extract 0.1-1%, vitamin E oil 0.1-1%, preservative 0.1-1%, Radix Zanthoxyli extract 0.1-1%, sodium monofluorophosphate 0.1-1%, allantoin 0.1-1%, tannic acid 0.05-0.2%, niacinamide 0.05-0.2%, German oil of chamomile 0.05-0.2%, menthol 0.05-0.2%, caryophyllus oil 0.05-0.2%, sweetener 0 .05-0.2%, zinc gluconate 0.05-0.2%, surplus are deionized water to 100%；Dental ulcer treatment agent of the invention mainly includes plant extracts, the simply effective rapid healing canker sore of energy.
Description
Technical field
The invention belongs to dental care agent fields, and in particular to a kind of dental ulcer treatment agent.
Background technique
Canker sore is commonly called as " aphtha ", and miliaria is grown etc..Refer to the common exedens illness of festering for betiding mucous membrane of mouth, it is more
The mucous membrane at the soft tissues such as intracavitary lip, tongue cheek and palate is seen, single or multiple yellow-whites occur for the positions such as vestibular ditch, soft palate
Round or ellipse is festered a little, and touching when feed, drinking water, brush teeth, or even speaking will feel significantly to ache at ulcer
Pain or burning heat sensation.The mucous membrane at these positions lacks keratinization layer or angling is poor.It brings inconvenience to daily life, and can concurrent mouth
Smelly, chronic pharyngitis, headache, dizziness, nausea, agitation, fever, enlargement of lymph nodes, it is possible to the constitutional symptoms such as carcinoma of mouth are developed into,
And the easy recurrent exerbation of these patients.
With the improvement of living standards, the incidence of canker sore is promoted instead, is especially generally occurred in coastal area, this with
Unbalanced diet is related with rest, this causes suffering to daily life and inconvenience.Traditional treatment canker sore medicine all uses by force
Strong bactericidal antiphlogistic medicine treatment, curer is painful and effect is poor.
Summary of the invention
The object of the invention is just to provide a kind of dental ulcer treatment agent, mainly includes plant extracts, can be simple and effective
Rapid healing canker sore.
A kind of dental ulcer treatment agent of the present invention, by weight ratio include: propylene glycol 1-3%, dodecyl sulphur
Sour sodium 2-5%, cold extraction resina liquidamberis medicinal extract 1-3%, thickener 1-2%, licorice 1-2%, calendula extract 1-2%,
Myrrha extract 1-2%, buffer 1-2%, Olibanum extract 0.1-1%, vitamin E oil 0.1-1%, preservative 0.1-1%,
Radix Zanthoxyli extract 0.1-1%, sodium monofluorophosphate 0.1-1%, allantoin 0.1-1%, tannic acid 0.05-0.2%, niacinamide
0.05-0.2%, German oil of chamomile 0.05-0.2%, menthol 0.05-0.2%, caryophyllus oil 0.05-0.2%, sweetener
0.05-0.2%, zinc gluconate 0.05-0.2%, surplus are deionized water to 100%.
The present invention additionally provides a kind of method for preparing dental ulcer treatment agent, comprising: and one, in a reservoir, it is added 5%
Deionized water, and it is heated to 60 degrees Celsius；Two, lauryl sodium sulfate is poured into container and is dissolved；Three, in a reservoir,
Addition triclosan, menthol, calendula extract, vitamin E oil, German oil of chamomile, natural caryophyllus oil add propylene glycol
It sufficiently does and mixes dissolution；Four, with remaining ionized water, allantoin is dissolved, then do mix be put into cold extraction resina liquidamberis medicinal extract, Radix Glycyrrhizae mentions
Take object, Myrrha extract, sodium bicarbonate, sodium lactate, Olibanum extract, Radix Zanthoxyli extract, sodium monofluorophosphate, niacinamide, Portugal
Grape saccharic acid zinc, potassium cinnamate；Five, it is whisking in cylinder, step 3 and liquid obtained in step 4 is sufficiently done and mix mixing, then gradually
Xanthan gum and CNC thickening is gradually added；Six, it is whisking in cylinder after mixing evenly, is being de-gassed to get transparent cream liquid.
Beneficial effects of the present invention:
In the present invention, cold extraction resina liquidamberis medicinal extract, licorice, Myrrha extract is dream team, has high biology
Charge adsorption ability, plant protoplasm state (close to sunlight ray state) is heavy to be attached to ulcer affected part, and blocks external substance entrance,
Anti-inflammatory analgetic is played, the effect of holding back is repaired.Sensitive toothache can be prevented again, and there is sterilizing inflammation-diminishing function, can remove the function eliminated bad breath in the oral cavity
Can, biological negative electricity lotus is combined rapidly with the ulcer surface mucous membrane under isoelectric point, plays quickly alleviating pain, rapid repairing ulcer effect.
In the present invention, cold extraction resina liquidamberis medicinal extract, licorice, the combination of Myrrha extract, with high biological charge
Adsorption capacity is avoided using fungicide and steroids.They are pure natural plant extract matter, have good bio-compatible
Property, oral cavity tissue will not be allowed to generate biological rejection, and can be absorbed by the body and utilize object to be beneficial.
Dental ulcer treatment agent of the invention can solve a variety of oral problems simultaneously, and effect is obvious, natural safety, nothing
The direction of mouth disease is actually treated in side effect from now on, and especially dental ulcer treatment is even more special efficacy, and most effective feature exists
Shimming ion is generated in easypro oral fluid, affected part is acted on and is received by receptor, stopping immediately pain does not stimulate.
Specific embodiment
With reference to embodiment, the content of present invention is described in detail in embodiment:
In the present invention, a kind of dental ulcer treatment agent, by weight ratio include: propylene glycol 1-3%, lauryl sodium sulfate
2-5%, cold extraction resina liquidamberis medicinal extract 1-3%, thickener 1-2%, licorice 1-2%, calendula extract 1-2%, myrrh
Extract 1-2%, buffer 1-2%, Olibanum extract 0.1-1%, vitamin E oil 0.1-1%, preservative 0.1-1%, two sides
Needle extract 0.1-1%, sodium monofluorophosphate 0.1-1%, allantoin 0.1-1%, tannic acid 0.05-0.2%, niacinamide 0.05-
0.2%, German oil of chamomile 0.05-0.2%, menthol 0.05-0.2%, caryophyllus oil 0.05-0.2%, sweetener 0.05-
0.2%, zinc gluconate 0.05-0.2%, surplus are deionized water to 100%.
Embodiment 1
As a preferred embodiment, in the present embodiment: composition ratio by weight include: the therapeutic agent by weight
Example includes: propylene glycol 3%, lauryl sodium sulfate 2.8%, cold extraction resina liquidamberis medicinal extract 2%, thickener 1.2%, licorice
1.3%, calendula extract 1.2%, Myrrha extract 1%, buffer 1%, Olibanum extract 0.5%, vitamin E oil
0.5%, preservative 0.35%, Radix Zanthoxyli extract 0.3%, sodium monofluorophosphate 0.3%, allantoin 0.3%, tannic acid 0.1%,
Niacinamide 0.1%, German oil of chamomile 0.1%, menthol 0.08%, caryophyllus oil 0.05%, sweetener 0.05%, gluconic acid
Zinc 0.05%, surplus are deionized water to 100%.
Wherein, the cold extraction resina liquidamberis medicinal extract contains cinnamic acid norbornene ester, cinnamic acid cinnamic alcohol ester by witch hazel plant extract
With white birch ester ketone acid；Buffer is made of sodium bicarbonate and two kinds of Pfansteihl sodium；Preservative includes: potassium cinnamate 0.15% and jade
Clean new 0.2%；Sweetener includes Sucralose 0.05%.
As a preferred technical solution, in the present invention, the dental ulcer treatment agent further includes Stomatocyte renovation agent, institute
Stating Stomatocyte renovation agent includes zinc gluconate 0.05%, and the thickener is made of xanthan gum and sodium carboxymethylcellulose.
It should be noted that the cold extraction resina liquidamberis medicinal extract, licorice, Myrrha extract, olibanum mention in the present invention
Take object, Radix Zanthoxyli extract, tannic acid, sodium monofluorophosphate, allantoin, niacinamide, zinc gluconate must it is completely soluble after,
Form clear solution.
In the present invention, oily matter, for example (,) calendula extract, triclosan, vitamin E oil, German oil of chamomile, peppermint
Brain, cloves oil substances etc. must be then added in solution after propylene glycol and lauryl sodium sulfate emulsification dissolution.
The present embodiment additionally provides a kind of method for preparing dental ulcer treatment agent, which comprises
One, 5% deionized water in a reservoir, is added, and is heated to 60 degrees Celsius；
Two, lauryl sodium sulfate is poured into container and is dissolved；
Three, triclosan, menthol, calendula extract, vitamin E oil, German oil of chamomile, day in a reservoir, is added
Right caryophyllus oil adds propylene glycol and sufficiently does and mixes dissolution；
Four, with remaining ionized water, allantoin is dissolved, then do mix be put into cold extraction resina liquidamberis medicinal extract, licorice,
Myrrha extract, sodium bicarbonate, sodium lactate, Olibanum extract, Radix Zanthoxyli extract, sodium monofluorophosphate, niacinamide, gluconic acid
Zinc, potassium cinnamate；
Five, it is whisking in cylinder, step 3 and liquid obtained in step 4 is sufficiently done and mix mixing, then Chinese life is added gradually
Glue and CNC thickening；
Six, it is whisking in cylinder after mixing evenly, is being de-gassed to get transparent cream liquid.
For dental ulcer treatment agent of the invention, following experiment has been done:
Experimental effect test
This research chooses 400 all ages and classes patients and is tracked research test, and the test age is 08It is 60 years old, coastal
Area is in the majority.4 groups are divided into, every group of 100 people.This 4 groups are respectively correspondingly contained using A, and dental ulcer treatment agent group is implemented
Object is closed, the commercially available chlorhexidine lozenge of B, the commercially available tabellae iodi gurgitis of C, D is commercially available to contain steroids emplastrum.Frequency of use is two times a day, persistently to make
With 3 days.Respectively to irritation, analgesic effect, therapeutic effect carries out test observation, and carries out questionnaire assessment by volunteer, comprehensive
Obtain data.Test result is as follows:
1, using effect after 2 minutes
Test: 5 points of expressions are very good, and 4 points indicate, 3 points of expressions are medium, and 2 points indicate not so good, and 1 point of expression is bad.
Test result:
A 5 divides 99% 4 points 1% 2 points 0% 1 points 0%
B 5 divides 10% 4 points 3% 2 points 1% 1 points 96%
C 5 divides 7% 4 points 1% 2 points 2% 1 points 90%
D 5 divides 26% 4 points 16% 2 points 5% 1 points 53%
From test 99% in patient 2 minutes at 5 points or more.It is obvious to implement dental ulcer treatment agent effect for visual effects.
2, using effect after 1 day
Test: 5 points of expressions are very good, and 4 points indicate, 3 points of expressions are medium, and 2 points indicate not so good, and 1 point of expression is bad.
Test average result:
A 5 divides 100% 2 points 0% 2 points 0% 1 points 0%
B 5 divides 10% 4 points 12% 2 points 7% 1 points 73%
C 5 divides 8% 4 points 13% 2 points 11% 1 points 68%
D 5 divides 16% 4 points 12% 2 points 16% 1 points 53%
From patient using test 100% after 1 day at 5 points or more.It is tall and erect to implement dental ulcer treatment agent effect for visual effects
More.
3, using effect after 2 days
Same test: 5 points of expressions are very good, and 4 points indicate, 3 points of expressions are medium, and 2 points indicate not so good, and 1 point indicates not
It is good.
Test result:
A 5 divides 100% 4 points 0% 2 points 0% 1 points 0%
B 5 divides 16% 4 points 20% 2 points 13% 1 points 51%
C 5 divides 11% 4 points 3% 2 points 3% 1 points 83%
D 5 divides 19% 4 points 15% 2 points 26% 1 points 40%
From patient using test 100% after 2 days at 5 points or more.It is tall and erect to implement dental ulcer treatment agent effect for visual effects
More.
4, using effect after 3 days
Same test: 5 points of expressions are very good, and 4 points indicate, 3 points of expressions are medium, and 2 points indicate not so good, and 1 point indicates not
It is good.
Test result:
A 5 divides 100% 4 points 0% 2 points 0% 1 points 0%
B 5 divides 36% 4 points 14% 2 points 10% 1 points 40%
C 5 divides 25% 4 points 12% 2 points 10% 1 points 53%
D 5 divides 44% 4 points 12% 2 points 18% 1 points 26%
From patient using test 100% after 3 days at 5 points or more.It is tall and erect to implement dental ulcer treatment agent effect for visual effects
More.
Embodiment 2
In the present embodiment, the dental ulcer treatment agent provided, by weight ratio and 1 different from of embodiment are specifically included:
Propylene glycol 1%, lauryl sodium sulfate 2%, cold extraction resina liquidamberis medicinal extract 1%, thickener 1%, licorice 1%, pot marigold
Extract 1%, Myrrha extract 1%, buffer 1%, Olibanum extract 0.1%, vitamin E oil 0.1%, preservative 0.1%,
Radix Zanthoxyli extract 0.1%, sodium monofluorophosphate 0.1%, allantoin 0.1%, tannic acid 0.05%, niacinamide 0.05%, Germany
Oil of chamomile 0.05%, menthol 0.05%, caryophyllus oil 0.05%, sweetener 0.05%, zinc gluconate 0.05%, surplus are
Deionized water is to 100%.
Embodiment 3
In the present embodiment, the dental ulcer treatment agent provided, by weight ratio and 1 different from of embodiment are specifically included:
Propylene glycol 3%, lauryl sodium sulfate 5%, cold extraction resina liquidamberis medicinal extract 3%, thickener 2%, licorice 2%, pot marigold
Extract 2%, Myrrha extract 2%, buffer 2%, Olibanum extract 1%, vitamin E oil 1%, preservative 1%, Radix zanthoxyli
Extract 1%, sodium monofluorophosphate 1%, allantoin 1%, tannic acid 0.2%, niacinamide 0.2%, German oil of chamomile 0.2%,
Menthol 0.2%, caryophyllus oil 0.2%, sweetener 0.2%, zinc gluconate 0.2%, surplus are deionized water to 100%.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of dental ulcer treatment agent, which is characterized in that therapeutic agent ratio by weight includes: propylene glycol 1-3%, and 12
Sodium alkyl sulfate 2-5%, cold extraction resina liquidamberis medicinal extract 1-3%, thickener 1-2%, licorice 1-2%, calendula extract
1-2%, Myrrha extract 1-2%, buffer 1-2%, Olibanum extract 0.1-1%, vitamin E oil 0.1-1%, preservative
0.1-1%, Radix Zanthoxyli extract 0.1-1%, sodium monofluorophosphate 0.1-1%, allantoin 0.1-1%, tannic acid 0.05-0.2%,
Niacinamide 0.05-0.2%, German oil of chamomile 0.05-0.2%, menthol 0.05-0.2%, caryophyllus oil 0.05-0.2%, sweet tea
Taste agent 0.05-0.2%, zinc gluconate 0.05-0.2%, surplus are deionized water to 100%.
2. dental ulcer treatment agent according to claim 1, which is characterized in that therapeutic agent ratio by weight includes:
Propylene glycol 3%, lauryl sodium sulfate 2.8%, cold extraction resina liquidamberis medicinal extract 2%, thickener 1.2%, licorice 1.3%,
Calendula extract 1.2%, Myrrha extract 1%, buffer 1%, Olibanum extract 0.5%, vitamin E oil 0.5%, anti-corrosion
Agent 0.35%, Radix Zanthoxyli extract 0.3%, sodium monofluorophosphate 0.3%, allantoin 0.3%, tannic acid 0.1%, niacinamide
0.1%, German oil of chamomile 0.1%, menthol 0.08%, caryophyllus oil 0.05%, sweetener 0.05%, zinc gluconate
0.05%, surplus is deionized water to 100%.
3. dental ulcer treatment agent according to claim 1 or 2, which is characterized in that the cold extraction resina liquidamberis medicinal extract is by gold
Thread plum plant extract, containing cinnamic acid norbornene ester, cinnamic acid cinnamic alcohol ester and white birch ester ketone acid.
4. dental ulcer treatment agent according to claim 1 or 2, which is characterized in that the buffer by sodium bicarbonate and
Two kinds of Pfansteihl sodium compositions.
5. dental ulcer treatment agent according to claim 1 or 2, which is characterized in that the preservative includes: potassium cinnamate
0.15% and triclosan 0.2%.
6. dental ulcer treatment agent according to claim 1 or 2, the sweetener includes Sucralose 0.05%.
7. dental ulcer treatment agent according to claim 1 or 2, which is characterized in that the dental ulcer treatment agent is also wrapped
Stomatocyte renovation agent is included, the Stomatocyte renovation agent includes zinc gluconate 0.05%.
8. dental ulcer treatment agent according to claim 1 or 2, which is characterized in that the thickener is by xanthan gum and carboxylic
Sodium carboxymethylcellulose pyce composition.
9. dental ulcer treatment agent according to claim 1 or 2, which is characterized in that the cold extraction resina liquidamberis medicinal extract, Radix Glycyrrhizae
Extract, Myrrha extract, Olibanum extract, Radix Zanthoxyli extract, tannic acid, sodium monofluorophosphate, allantoin, niacinamide, Portugal
Grape saccharic acid zinc must it is completely soluble after, formed clear solution.
10. a kind of method for preparing dental ulcer treatment agent, which is characterized in that the described method includes:
One, 5% deionized water in a reservoir, is added, and is heated to 60 degrees Celsius；
Two, lauryl sodium sulfate is poured into container and is dissolved；
Three, triclosan, menthol, calendula extract, vitamin E oil, German oil of chamomile, natural fourth in a reservoir, is added
Sesame oil adds propylene glycol and sufficiently does and mixes dissolution；
Four, with remaining ionized water, allantoin is dissolved, then does to mix being put into cold extraction resina liquidamberis medicinal extract, licorice, myrrh
Extract, sodium bicarbonate, sodium lactate, Olibanum extract, Radix Zanthoxyli extract, sodium monofluorophosphate, niacinamide, zinc gluconate,
Potassium cinnamate；
Five, whisking in cylinder, step 3 and liquid obtained in step 4 sufficiently done and mix mixing, then gradually be added xanthan gum and
CNC thickening；
Six, it is whisking in cylinder after mixing evenly, is being de-gassed to get transparent cream liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201910242258.5A CN109745354A (en) | 2019-03-28 | 2019-03-28 | A kind of dental ulcer treatment agent |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910242258.5A CN109745354A (en) | 2019-03-28 | 2019-03-28 | A kind of dental ulcer treatment agent |
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| CN109745354A true CN109745354A (en) | 2019-05-14 |
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| CN201910242258.5A Pending CN109745354A (en) | 2019-03-28 | 2019-03-28 | A kind of dental ulcer treatment agent |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022036774A1 (en) * | 2020-08-17 | 2022-02-24 | 广东盛普生命科技有限公司 | Application of tannic acid in preparation of anti-respiratory virus drug |
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| CN102488715A (en) * | 2011-12-15 | 2012-06-13 | 张家界奥威科技有限公司 | Natural oral cavity disinfectant and preparation method thereof |
| CN105168769A (en) * | 2015-09-06 | 2015-12-23 | 王璐 | Traditional Chinese medicine for treating oral ulcer |
| CN108618980A (en) * | 2018-06-08 | 2018-10-09 | 叶绿芝生物科技（中山）有限公司 | A kind of multi-functional liquid tooth paste |
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2019
- 2019-03-28 CN CN201910242258.5A patent/CN109745354A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1044048A (en) * | 1990-01-19 | 1990-07-25 | 同济医科大学附属同济医院 | Absorbable slow-solution medicinal membrane and preparation method thereof |
| CN102488715A (en) * | 2011-12-15 | 2012-06-13 | 张家界奥威科技有限公司 | Natural oral cavity disinfectant and preparation method thereof |
| CN105168769A (en) * | 2015-09-06 | 2015-12-23 | 王璐 | Traditional Chinese medicine for treating oral ulcer |
| CN108618980A (en) * | 2018-06-08 | 2018-10-09 | 叶绿芝生物科技（中山）有限公司 | A kind of multi-functional liquid tooth paste |
Non-Patent Citations (1)
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2022036774A1 (en) * | 2020-08-17 | 2022-02-24 | 广东盛普生命科技有限公司 | Application of tannic acid in preparation of anti-respiratory virus drug |
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