CN109655478A - A kind of flash detecting device - Google Patents

A kind of flash detecting device Download PDF

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Publication number
CN109655478A
CN109655478A CN201811522483.6A CN201811522483A CN109655478A CN 109655478 A CN109655478 A CN 109655478A CN 201811522483 A CN201811522483 A CN 201811522483A CN 109655478 A CN109655478 A CN 109655478A
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China
Prior art keywords
darkroom
cabinet
detecting device
sample
flash detecting
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Granted
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CN201811522483.6A
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Chinese (zh)
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CN109655478B (en
Inventor
王琴
陈俊
汪孟
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Shenzhen Furuikang Technology Co Ltd
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Shenzhen Furuikang Technology Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • G01N23/22Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by measuring secondary emission from the material
    • G01N23/227Measuring photoelectric effect, e.g. photoelectron emission microscopy [PEEM]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • G01N23/22Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by measuring secondary emission from the material
    • G01N23/2202Preparing specimens therefor

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measurement Of Radiation (AREA)

Abstract

The present invention relates to detection device technical fields, provide a kind of flash detecting device, including cabinet, darkroom, scintillation detector and objective table, darkroom, scintillation detector and objective table are mounted in cabinet, so as to carry out flicker detection under shading environment, first open butt joint of scintillation detector and darkroom, to incude to the β ray of the sample to be tested release in darkroom;The carrying position for carrying sample to be tested is provided on objective table, when objective table is located in darkroom, it carries position and corresponds to the first opening, so that scintillation detector incudes the β ray that sample to be tested discharges, detection time is short, high-efficient, darkroom can avoid being influenced scintillation detector to Beta-ray induction because being interfered by ambient simultaneously, to improve the accuracy of detection;The position that second opening in darkroom is corresponded on cabinet is provided with hatch, and objective table passes in and out cabinet by hatch, sample to be tested brought or taken out of into cabinet, simple, convenient.

Description

A kind of flash detecting device
Technical field
The present invention relates to detection device technical field more particularly to a kind of flash detecting devices.
Background technique
Helicobacter pylori is gastritis, the main pathogenic bacteria of gastroduodenal ulcer, and is the I class carcinogen of gastric cancer, Diagnosing helicobacter helicobacter infection is the key that early detection, early stage elimination eliminating pylorus (Hp) accurately and in time.
Urea breath test has very high specificity and sensibility to the diagnosis that helicobacter pylori (Hp) infects, and has There are Noninvasive, safe and harmless, no pain.The principle of breath test is generated in vivo based on helicobacter pylori (Hp) A large amount of urease, method are first to take orally the urea drug of isotope labelling carbon to the infected, then generate after urea is decomposed Isotope labelling carbon dioxide is breathed out from lung, collects specimen of breath, detects isotope labelling CO with instrument2Amount, positive patient The CO of isotope labelling2Obviously increase, the sensibility and specificity for detecting helicobacter pylori (Hp) is high, and helicobacter pylori (Hp) CO of isotope labelling is then breathed out after removing2Amount reduce or disappear.
The urea of clinical use at present14C breath test includes liquid scintillation (liquid sudden strain of a muscle) counting method and two kinds of cassette mensuration Form.(1) liquid scintillation (liquid sudden strain of a muscle) counting method (liquid scintillating counting) is to be used as to penetrate by scintillation solution The medium of heat input transmitting is first converted β ray by special scintillation solvent come a kind of radioactivity survey technology carried out The Beta-ray rate of disintegration is measured at the light of certain wavelength, then by flash detecting device, but this method need to use toxic reagent, to Survey person is easy to splash when sampling or suck-back entrance, cumbersome.(2) cassette mensuration uses lid-leather (GM) counting method, is to pass through β ray directly causes the mode of ionized inert gas to measure the Beta-ray rate of disintegration in G-M counting tube, dodges with traditional liquid Unlike bright counting method, this method does not need darkroom and special lead screen, without carrying out special amplification to signal, is not necessarily to liquid Aspect product, solve the problems, such as liquid scintillation counting, but due to14The β ray of C decay release belongs to low energy beta rays, penetrates energy Power is weak, and low using this method measurement efficiency, the testing time is long, and is influenced by background counting rate, accuracy rate bottom, be unfavorable for and When, accurately diagnosing helicobacter pylori infection conditions.
Therefore, the new technical solution of one kind need to be provided to solve the problems, such as that breath test detection efficiency is low low with accuracy rate.
Summary of the invention
The present invention is intended to provide a kind of flash detecting device, to solve the low skill low with accuracy rate of breath test detection efficiency Art problem.
The technical proposal adopted by the invention to solve the above technical problems is that:
Provide a kind of flash detecting device, including cabinet, darkroom, scintillation detector and objective table, it is the darkroom, described Scintillation detector and the objective table are mounted in the cabinet;The darkroom is provided with the first opening, the flash detection The end of probe of device and first open butt joint;It is additionally provided with the second opening on the darkroom, the objective table passes through described the Two openings pass in and out the darkroom, and the carrying position for carrying sample to be tested or sample loading attachment is provided on the objective table, When the objective table is located in the darkroom, the carrying position and first opening are opposite;Described is corresponded on the cabinet The position of two openings is provided with hatch, and the objective table passes in and out the cabinet by the hatch.
As an improvement of the above technical solution, the scintillation detector includes photomultiplier tube;First opening is set to The top surface in the darkroom, the photomultiplier tube are vertically installed at the top in the darkroom, the cathode terminal of the photomultiplier tube With first open butt joint;When the objective table is located in the darkroom, the carrying position corresponds to first opening Lower section.
As a further improvement of the above technical scheme, the carrying position is equipped with for carrying sample to be tested or the sample The mounting groove of loading attachment.
As a further improvement of the above technical scheme, the bottom of the cabinet is fixedly installed the first mounting rack, described Darkroom is fixedly mounted on first mounting rack.
As a further improvement of the above technical scheme, the bottom of the cabinet is fixedly installed the first mounting rack, described A cover is fixedly installed on first mounting rack, the cover and first mounting rack surround the darkroom jointly.
It as a further improvement of the above technical scheme, further include power device and transmission device, the power device is solid Dingan County is loaded on the lower section in the darkroom, and the inside in the darkroom is arranged in the transmission device, and the darkroom offers third and opens Mouthful, the power device is open by the third and is connect with the transmission device, and the transmission device and the objective table connect It connects.
As a further improvement of the above technical scheme, the transmission device includes rack and pinion, the rack gear and institute It states objective table to be fixedly connected, the gear is set on the output shaft of the power device, and the gear is engaged with the rack gear.
It as a further improvement of the above technical scheme, further include slide track component, the objective table passes through the slide rail group Part is slidably connected with the darkroom.
As a further improvement of the above technical scheme, the slide track component includes sliding rail, the first mounting bar and the second peace Item is filled, first mounting bar is fixedly connected on the bottom surface in the darkroom, second mounting bar and the fixed company of the objective table It connects;First mounting bar is fixed or be slidably connected to the sliding rail, and second mounting bar is slidably connected to the sliding rail.
It as a further improvement of the above technical scheme, further include scanning means, the scanning means is fixedly installed in institute The lower section in darkroom is stated, the position that the darkroom corresponds to the scanning means offers the 4th opening.
As a further improvement of the above technical scheme, the cabinet is internally provided with the second mounting rack, and described second Mounting rack is located at the top in the darkroom, and the photomultiplier tube is fixedly mounted on second mounting rack.
As a further improvement of the above technical scheme, it is provided with fixing seat and supporting plate on second mounting rack, it is described Fixing groove is provided in fixing seat, the supporting plate is fixedly mounted on the fixing seat, and the supporting plate and the fixing groove are to institute The outer wall progress for stating photomultiplier tube is circumferentially fixed.
It as a further improvement of the above technical scheme, further include power supply device, the power supply device is fixedly mounted on institute It states on the second mounting rack or the cabinet.
As a further improvement of the above technical scheme, display device is provided on front side of the cabinet, in the cabinet Equipped with control module, the display device and the scintillation detector are electrically connected with the control module respectively.
As a further improvement of the above technical scheme, the front side of the cabinet includes an inclined installation from front to back Portion, the display device are fixedly installed on the mounting portion, and the control module is set to the back of the display device.
As a further improvement of the above technical scheme, the bottom of the cabinet offers blow vent, the cabinet it is upper Portion offers exhaust outlet, and the exhaust ports are provided with exhaust apparatus.
As a further improvement of the above technical scheme, the cabinet includes boxboard, and the hatch is provided with the boxboard On, the baffle for closing hatch is provided at the hatch, the baffle is rotatably connected at the hatch.
As a further improvement of the above technical scheme, the hatch periphery is provided with inward-facing from the appearance of the boxboard The installation groove of recess, the position that the inside of the baffle corresponds to the installation groove are provided with fin, and the baffle closes institute When stating hatch, the fin is located in the installation groove.
As a further improvement of the above technical scheme, the end of probe of the scintillation detector and enter the darkroom after X-ray excited polycrystalline structure scintillator is provided between sample to be tested.
As a further improvement of the above technical scheme, the X-ray excited polycrystalline structure scintillator is set to the detection of the scintillation detector At end.
As a further improvement of the above technical scheme, the solid scintillator is attached to the sample to be tested.
As a further improvement of the above technical scheme, the sample loading attachment is provided with for loading sample to be tested Loading chute, the X-ray excited polycrystalline structure scintillator are set at the notch of the loading chute.
As a further improvement of the above technical scheme, the sample loading attachment is equipped with inflatable mouth, inlet channel and goes out Gas channel, the inflatable mouth, the inlet channel, the loading chute and the outlet passageway are sequentially communicated.
As a further improvement of the above technical scheme, the X-ray excited polycrystalline structure scintillator is that solid-state flashes film, the solid-state flashing Film is attached at the notch of the loading chute.
The beneficial effects of the present invention are:
Flash detecting device of the invention includes cabinet, darkroom, scintillation detector and objective table, darkroom, scintillation detector It is mounted in cabinet with objective table, so as to carry out flicker detection under shading environment, darkroom is provided with the first opening and Two openings, scintillation detector and the first open butt joint, so that the β ray discharged to sample to be tested in darkroom incudes;Loading The carrying position for carrying sample to be tested is provided on platform, when objective table is located in darkroom, carrying position corresponds to the first opening, can Detect scintillation detector accurately to the sample to be tested on objective table.Since the β ray that sample to be tested releases is Low energy ray, penetration power is weaker, then is detected by the way that sample to be tested to be placed in darkroom, can promote the accuracy rate of detection, The detection time of the detection is short, detection efficiency is high;Darkroom is the further shading of sample to be tested simultaneously, is avoided because dry by ambient It disturbs and influences scintillation detector to Beta-ray induction, the accuracy of detection also can be improved.In addition, corresponding second opening on cabinet Position be provided with hatch, objective table passes in and out cabinet by hatch, sample to be tested is brought or taken out of into cabinet, it is easy to operate, It is convenient.
Detailed description of the invention
To describe the technical solutions in the embodiments of the present invention more clearly, make required in being described below to embodiment Attached drawing briefly describes:
Fig. 1 is the structural schematic diagram of flash detecting device one embodiment of the present invention;
Fig. 2 is the schematic diagram of internal structure of flash detecting device one embodiment of the present invention;
Fig. 3 is the structural schematic diagram of the one embodiment in darkroom in the present invention;
Fig. 4 is the structural schematic diagram of detection module one embodiment in the present invention;
Fig. 5 is a cross-sectional view of embodiment illustrated in fig. 4;
Fig. 6 is partial sectional view at the hatch of one embodiment of the invention;
Fig. 7 is the structural schematic diagram of an implementation of hatch of the invention;
Fig. 8 is the structural schematic diagram of one embodiment of baffle in cabinet of the invention.
Specific embodiment
It is carried out below with reference to the technical effect of 1~8 pair of design of the invention of embodiment and attached drawing, specific structure and generation It clearly and completely describes, to be completely understood by the purpose of the present invention, feature and effect.Obviously, described embodiment is this A part of the embodiment of invention, rather than whole embodiments, based on the embodiment of the present invention, those skilled in the art are not being paid Other embodiments obtained under the premise of creative work out, belong to the scope of protection of the invention.In addition, involved in patent All connection/the connection relationships arrived not singly refer to that component directly connects, and addition can be passed through according to specific implementation situation by referring to Or reduce couple auxiliary, Lai Zucheng more preferably coupling structure.The orientation such as upper and lower, left and right involved in the present invention describe only It is relative to the position relationship of the components of the invention in the accompanying drawings.Each technical characteristic in the present invention, It can be with combination of interactions under the premise of not conflicting conflict.
Flash detecting device of the invention is used for urea breath test, by there is the sample of testee's exhaled gas to collection It is detected, is obtained in sample14The Beta-ray amount that C is released, to be diagnosed to helicobacter pylori (Hp) infection.
Fig. 1 is the structural schematic diagram of flash detecting device one embodiment of the present invention, and Fig. 2 is flash detecting device of the present invention The schematic diagram of internal structure of one embodiment, with reference to Fig. 1,2, flash detecting device includes cabinet 1, darkroom 2, flash detection Device 3 and objective table 4 (being located in darkroom 2, reference can be made to Fig. 4), darkroom 2, scintillation detector 3 and objective table 4 are mounted on cabinet 1 Inside, so as to carry out flicker detection under shading environment, darkroom 2 is provided with the first opening 21 (reference can be made to Fig. 3) and second and opens 22 (reference can be made to Fig. 4) of mouth, scintillation detector 3 are docked with the first opening 21, so as to the β ray to the sample to be tested release in darkroom Incuded;The carrying position for carrying sample to be tested or sample loading attachment is provided on objective table 4, objective table 4 is located at dark When in room 2, carrying position is opposite with the first opening 21, so that scintillation detector is in the sample to be tested in darkroom 214C decay release β ray incuded.β ray can make X-ray excited polycrystalline structure scintillator issue optical signal for flash detection by excitation X-ray excited polycrystalline structure scintillator Device is detected, then can avoid using the virose liquid scintillation solvent of tool as transmitting medium, appearance when preventing person under test from sampling Easy splash solvent or suck-back entrance, easy to operate, safety.Since the β ray that sample to be tested releases is low energy ray, penetrate Power is weaker, then is detected by the way that sample to be tested to be placed in darkroom together with X-ray excited polycrystalline structure scintillator, and one side scintillation detector can be with Directly incude the optical signal that dark indoor β ray is converted, on the other hand, darkroom 2 is that sample to be tested carries out shading, can avoid because It is interfered by ambient and influences scintillation detector pair14The induction for the optical signal that the low energy beta rays of C decay release are converted, from And the accuracy rate of detection can be improved, the detection time of the detection is short, detection efficiency is high.In addition, objective table 4 can be by sample to be tested band Enter or take out of cabinet 1, the operation of detection can be facilitated.
Fig. 3 is the structural schematic diagram of the one embodiment in darkroom 2 in the present invention, and Fig. 4 is detection module one in the present invention The structural schematic diagram of embodiment, with reference to Fig. 3,4, in the present embodiment, the top surface in darkroom 2 is provided with the first opening 21, flashing Detector 3 be can be stimulated to scintillator caused by the device that is detected of optical signal may include in the present embodiment light The top in darkroom 2 is placed vertically and are fixedly mounted on to electric multiplier tube, photomultiplier tube, and the cathode terminal of photomultiplier tube is (i.e. above-mentioned End of probe) it is docked with the first opening 21, and be aligned into the sample to be tested in darkroom 2, so as to be flashed to sample to be tested The flicker detection principle of detection, photomultiplier tube is techniques known, and this will not be repeated here.
The second opening 22 is additionally provided on darkroom 2, objective table 4 passes in and out darkroom 2 by the second opening 22, sets on objective table 4 It is equipped with the carrying position (not shown go out) for carrying sample to be tested or sample loading attachment, when objective table 4 is located in darkroom 2, is held The corresponding lower section for being located at the first opening 21 in position for carrying position, so that the end of probe with scintillation detector is corresponding.Carrying position is equipped with For carrying the mounting groove of sample to be tested or sample loading attachment, the positioning convenient for sample to be tested or sample loading attachment is fixed.
The position of corresponding second opening 22 is provided with hatch 11 (with reference to Fig. 1) on cabinet 1, objective table 4 by hatch 11 into Cabinet 1 out is realized the feeding of sample to be tested or is exited.
With reference to Fig. 2,3, in the present embodiment, the bottom of cabinet 1 is fixedly installed the first mounting rack 25, the first mounting rack A cover 26 is fixedly installed on 25, the top surface 251 of the cover 26 and the first mounting rack 25 is surrounded jointly for flashing test Darkroom 2, the top surface 251 of the first mounting rack 25 constitute the bottom surface in darkroom 2.
In another embodiment of the invention, the darkroom 2 for flashing test can be a box body, and darkroom 2 is fixed It is mounted on the first mounting rack 25, in this embodiment, the first mounting rack 25 is used only for fixed darkroom 2, without as dark The component part of room 2.
With reference to Fig. 2, since scintillation detector 3 has certain length, scintillation detector 3 is vertically docked with darkroom 2, from And longitudinal layout is longitudinally formed inside cabinet 1, so that the upper layer inside cabinet 1 is other than the top of scintillation detector 3, it is also surplus Space utilization rate is improved, reasonable, compact, orderly layout is conducive to install other devices in remaining biggish space.Cabinet 1 Be internally provided with the second mounting rack 12, the second mounting rack 12 is located at the top in darkroom 2 so that inside cabinet 1 formed above and below Mounting structure provides the platform in the middle and upper part installing device of cabinet 1, helps to make full use of the upper layer inside cabinet 1 empty Between, space utilization rate is improved, and reduce lateral volume, to reduce area occupied.
Scintillation detector 3 is vertically arranged, and is fixedly mounted on the second mounting rack 12.It is provided on second mounting rack 12 solid Reservation 121 and supporting plate 122 are provided with fixing groove in fixing seat 121, and supporting plate 122 is fixedly mounted in fixing seat 121, supporting plate 122 It is circumferentially fixed with outer wall progress of the fixing groove to scintillation detector 3, so that scintillation detector 3 is reliably fixed, also, supporting plate 122, it is provided with cushion between fixing groove and the outer wall of scintillation detector 3, to adapt to the outer wall of scintillation detector 3, avoids holding in the palm The outer wall of plate 122, fixing groove and scintillation detector 3 directly clamps and collides or scratch.
In addition, the flash detecting device of the present embodiment further includes being somebody's turn to do for providing the power supply device 5 of electric energy for internal components Power supply device 5 is fixedly mounted on 12 top of the second mounting rack, to make full use of the upper space inside cabinet 1, so that internal device Part compact layout is reasonable.
With reference to Fig. 1, the front side of cabinet 1 is provided with display device 7, and control module (not shown go out), display are equipped in cabinet 1 Device 7 and scintillation detector 3 are electrically connected with control module respectively;The display device 7 can be touching display screen, be also possible to not Display screen with touch function, when display device 7 is the display screen without touch function, which can lead to Setting USB interface is crossed to connect mouse, to realize operation control.As a result, by carrying out clicking operation or touch-control in display device 7 The operation control to related work device in detection process may be implemented in operation, for example can pass through the operation in display device 7 The disengaging etc. of objective table is realized, in addition, can also show the result of detection by display device 7.The front side of cabinet 1 includes one Inclined mounting portion 16, display device 7 are fixedly installed on mounting portion 16 from front to back, so that display device 7 is from front to back Inclination, convenient for the observation and operation of operator, control module can be set to the back of display device 7, machine in a manner of master control borad The top of case 1 provides enough inclined spaces, can be according to specific needs under the premise of chassis bottom area occupied is constant Corresponding tilt angle is set, to improve the utilization rate in space, it is longitudinal further to embody flash detecting device internal structure The advantage of layout.
The top of cabinet 1 is equipped with printing equipment 6, which can be used for printing detection data etc., printing equipment 6 Lower part the inside of cabinet 1 is protruded into from the top of cabinet 1, to make full use of the upper space inside cabinet 1, so that internal components cloth Office's compact and reasonable.In addition, also external printer can be connected by the USB interface on flash detecting device, it is more detailed to realize Detection data result printing.
With reference to Fig. 2,1 internal components of cabinet are longitudinally laid out, so that internal structure is compact, the bottom of cabinet 1 offers ventilation Mouth 13, the top of cabinet 1 offers exhaust outlet, and exhaust ports are provided with exhaust apparatus, and exhaust apparatus is exhaust in the present embodiment Fan 14, or other exhaust apparatus generally in the art.The exhaust outlet of the present embodiment is arranged on the back of cabinet 1, position Set it is on the upper side and corresponding with power supply device 5, to form air from 1 bottom of cabinet to top rear face in cabinet 1 in exhaust Channel, outside air from blow vent 13 enter cabinet 1 inside, and by exhaust outlet be discharged, gas discharge when flow through power device, Darkroom, scintillation detector and power supply device etc., the heat generated when so that the 1 each device in inside of cabinet being worked are taken out of, improve and dissipate Thermal energy power.
Fig. 5 is a cross-sectional view of embodiment illustrated in fig. 4, and with reference to Fig. 3,4,5, flash detecting device further includes power Device 81, transmission device 82, slide track component 9 and scanning means 10, power device 81 and transmission device 82 are used for band dynamic object stage 4 Movement, to be sent into or exit darkroom 2 for sample to be tested.Power device 81 is fixedly mounted on the first mounting rack 25 and is located at dark The lower section of room 2, transmission device 82 are arranged in the inside in darkroom 2, and darkroom 2 offers third opening 23, and power device 81 passes through the Three openings 23 are connect with transmission device 82, and transmission device 82 is connect with objective table 4, and objective table 4 passes through slide track component and darkroom 2 It is slidably connected, power device 81 can be moved by driving transmission device 82 come band dynamic object stage 4 as a result,.In the present embodiment, power Device 81 is electric motor, and transmission device 82 includes rack gear 822 and gear 821, and rack gear 822 is fixedly connected with objective table 4, gear 821 are set on the output shaft of electric motor, and gear 821 is engaged with rack gear 822, electrical motor driven gear 821 rotation to Band carry-over bar 822 moves, thus the movement with dynamic object stage 4 relative to darkroom 2.In the specific implementation, power device 81 can adopt With other conventional dynamical elements, transmission device 82 can also not arranged one by one herein using other conventional linear transmission mechanisms It lifts.In addition, above-mentioned slide track component 9 includes sliding rail 92, the first mounting bar 91 and the second mounting bar 93, the first mounting bar 91 is fixed to be connected It is connected to the bottom surface in darkroom 2, the second mounting bar 93 is fixedly connected with objective table 4, and sliding rail 92 is set to the first mounting bar 91 and the second peace It fills between item 93, and is slidably connected to the first mounting bar 91, and the second mounting bar 93 is slidably connected on sliding rail 92, it is possible thereby to Realize the opposite sliding between objective table 4 and darkroom 2;It, can to realize being slidably connected between the second mounting bar 93 and sliding rail 92 Ball is arranged between the second mounting bar 93 and sliding rail 92, for being slidably connected between the first mounting bar 91 and sliding rail 92 It can be such;It is to be herein pointed out in other embodiments, being also possible to fix between sliding rail 92 and the first mounting bar 91 Connection.
In the present embodiment, scanning means 10 is fixedly mounted on the lower section on the first mounting rack 25 and being located at darkroom 2, darkroom The positions of 2 corresponding scanning means 10 offer the 4th opening 24, the 4th opening 24 simultaneously with the sample to be tested be sent into darkroom 2 Corresponding, scanning means 10 scans the bar code information being sticked on sample to be tested or sample loading attachment simultaneously by the 4th opening 24 It is transferred to above-mentioned control module.A hood 27 is provided with outside power device 8 and scanning means 10, hood 27 is fixedly mounted On the first mounting rack 25, it is used for shading, is entered in darkroom to avoid light from the 23, the 4th opening 24 of third opening, to keep away Exempt to interfere.
When assembly, first the components for needing to be mounted on the first mounting rack 25 can be installed in advance, be reloaded into cabinet 1 Installation is fixed in inside, reduces assembly difficulty.
Fig. 6 is partial sectional view at the hatch of one embodiment of the invention, and Fig. 7 is an implementation of hatch of the invention Structural schematic diagram, Fig. 8 is the structural schematic diagram of one embodiment of baffle in cabinet of the invention, with reference to Fig. 6 to 8, machine Case 1 includes several boxboards, offers the hatch 11 for above-mentioned objective table disengaging cabinet 1 on the boxboard of the front side of cabinet 1, at hatch 11 It is provided with the baffle 17 for closing hatch 11, baffle 17 and cabinet are hinged, to be rotatably connected at hatch 11, baffle Torsional spring 18 is installed, first end 181 is connect with baffle 17, and second end 182 is connected to the hatch of boxboard between 17 and hatch 11 11 edges, after being installed, there are certain windup-degrees at the both ends of torsional spring 18, so that prestoring corresponding torsion in torsional spring 18 Square, so that the holding of baffle 17 reclines with boxboard, so that hatch 11 be kept to be in close state;Baffle 17 is pushed to open hatch 11 When, the rotation of baffle 17 is to further twist torsional spring 18, so that 18 accumulation of energy of torsional spring, the effect of torsional spring 18 is so that baffle 17 can be automatic It closes, to prevent ambient from entering 1 inside of cabinet from hatch 11 and generating interference to detection.
Specifically, 11 periphery of hatch is provided with the installation groove 19 being downwardly recessed from boxboard, baffle 17 The position that inside corresponds to installation groove 19 is provided with fin 171, and when baffle 17 closes hatch, fin 171 is located in groove 19.Gear First mounting base 172 is set on plate 17, the second mounting base 197 is set at hatch 11, baffle 17 passes through the first mounting base 172 and the Two mounting bases 197 are hinged, so that the baffle 17 can rotate at the hatch 11 of cabinet 1.
Installation groove 19 include upper groove 191,194 4 sections of lower groove 192, left groove 193 and right groove grooves, this four sections The end to end installation groove 19 for forming rectangle of groove;Fin 171 on baffle 17 includes upper fin 1711,1712 and of left fin 1,713 3 sections of right fin respectively corresponds 194 3 sections of upper groove 191, left groove 193 and right groove grooves of installation groove 19.On Groove 191,194 3 sections of grooves of left groove 193 and right groove bottom be provided with the first cushion block 195.It is convex on the inside of baffle 17 Rib 1711, left fin 1712 and right fin 1713 are located in upper groove 191, left groove 193 and right groove 194 and are resisted against On first cushion block 195.The second cushion block 196 is provided on supporting walls between lower groove 192 and hatch 11, baffle 17 closes hatch When 11, the inner wall of baffle 17 is resisted against on the second cushion block 196.The cooperation of installation groove 19 and fin 171, avoids ambient From the gap direct projection of baffle 17 and boxboard 11 to cabinet inside, the shading performance at cabinet hatch 11 is improved, ambient is avoided Interference to flicker detection.First cushion block 195 and the second cushion block 196 can play anticollision buffer function and further shading, prevent Gap light leakage between baffle plate 17 and boxboard 11, helps to improve the accuracy rate of flicker detection.
In the present embodiment, β ray can make X-ray excited polycrystalline structure scintillator issue optical signal for dodging by excitation X-ray excited polycrystalline structure scintillator Bright detector 3 is detected.The solid scintillator may be disposed at scintillation detector end of probe and enter darkroom after to test sample Between product, preferably, the end of probe of the scintillation detector can be close to X-ray excited polycrystalline structure scintillator, to promote Detection accuracy.It is specific next It says, at the end of probe which can be set to scintillation detector in a manner of solid-state scintiphoto or the solid-state flashes Solid-state flashing powder is mixed on the outer surface or sample to be tested that body can be wrapped in sample to be tested in such a way that solid-state flashes film At the notch for the loading chute that sample loading attachment can be arranged in end or X-ray excited polycrystalline structure scintillator in a manner of solid-state scintiphoto.It is logical It crosses using X-ray excited polycrystalline structure scintillator and realizes flicker detection, safety and the convenience of detection operation can be promoted.In addition, by will be to Sample and X-ray excited polycrystalline structure scintillator, which are collectively disposed in same darkroom, realizes detection, can promote detection efficiency and Detection accuracy.
It should be noted that the sample loading attachment (not shown) of the present embodiment is in addition to having the function of loading sample Outside, there can also be gas collecting, i.e., the sample loading attachment, which can be, allows person under test to blow and collect person under test The sample collecting apparatus, such as gas collection card etc. of institute's exhaled gas.The sample collecting apparatus can be equipped with inflatable mouth, inlet channel and go out Gas channel, the inflatable mouth, inlet channel, loading chute and outlet passageway can be sequentially communicated, and solid-state flashing film can be attached at dress in advance Carry slot notch at, thus, person under test taken the carbon containing isotope labelling urea drug (such as urea [14C] drug) after, The carbon dioxide with isotope labelling carbon can be breathed out by decomposing the urea drug in person under test's body, then blown when person under test is opposite After mouth is blown, the sample carrier being pre-placed in the loading chute of the sample collecting apparatus can absorb two with isotope labelling carbon Carbonoxide becomes sample to be tested, thus completes sample acquisition;Wherein, sample carrier is substantially a kind of absorbing component, can be by cotton Matter or non-woven fabrics substrate are made plus the adsorbent that can be used for adsorbing carbon dioxide gas, can absorb in person under test's exhaled gas Carbon dioxide.In turn, which can be placed on the mounting groove of objective table 4 enters in darkroom 2 in company with objective table 4 So that scintillation detector 3 carries out flicker detection to sample to be tested.
In addition, it is also worth pointing out that commercial product such as scintillation crystal, modeling had both can be used in the X-ray excited polycrystalline structure scintillator of the present embodiment Expect scintillator, flashing particle, scintillator powder etc., homemade all kinds of X-ray excited polycrystalline structure scintillators also can be used.The scintillator material of selection Material needs can quilt14The β ray of C excites, and the spectral region emitted should be consistent with the probe response range of scintillation detector.It is typical Photo-multiplier tube type scintillation detector plastic scintillant such as acrylic acid plastic scintillant, polystyrene scintillator, poly- can be selected Bis- 2, the 5- oxazolyl phenyl benzene (POPOP) of 2,5-, bis- isoxazolyl benzenesulfonamide (PPO) Isosorbide-5-Nitrae-, p-terphenyl etc. also can be selected in naphthalene rouge scintillator etc. Coating, the particle etc. of scintillator production.The embodiment of the present invention does not limit the shape of X-ray excited polycrystalline structure scintillator, size and thickness System, when can be configured according to actual needs.
The testing process of the present embodiment can be as follows:
Person under test is allowed to take the urea drug of the carbon containing isotope labelling;
Sample carrier of the person under test against above-mentioned sample to be tested or the sample collecting apparatus equipped with the sample carrier is allowed to carry out It exhales, can stop exhaling after the sustained exhalation time has reached setting time;
The sample to be tested for having acquired gas or sample collecting apparatus are placed on the objective table 4 of flash detecting device, made Objective table 4 enters in darkroom 2 to be detected for scintillation detector 3;
Testing result is shown by the display device 7 of flash detecting device.
It should be noted that person under test taken with isotope labelling carbon urea drug (such as urea [14C] drug) Afterwards, the carbon dioxide with isotope labelling carbon can be decomposited from the urea drug in vivo, later person under test to sample carrier or Sample loading attachment equipped with sample carrier is exhaled, and sample carrier can be made to absorb the carbon dioxide with isotope labelling carbon and formed For sample to be tested, sample to be tested or above-mentioned sample loading attachment equipped with sample are then placed in objective table 4 again Mounting groove on, entering objective table 4 in darkroom 2 can make above-mentioned scintillation detector 3 complete detection.Above-mentioned sample to be tested Because adsorbed isotope labelling carbon [14C] carbon dioxide, low energy beta rays can be radiated, the β ray penetration power is weaker, thus Sample and X-ray excited polycrystalline structure scintillator to be tested are placed in same darkroom by objective table 4 and realize detection, so that sample to be tested The β ray that product radiate closely can excite X-ray excited polycrystalline structure scintillator to issue optical signal without barrier, and scintillation detector 3 can directly incude Above-mentioned optical signal, in addition, darkroom structure additionally provides preferable dark conditions, so that flicker detection equipment was detected Accuracy rate and efficiency are higher, also fairly simple in operation, conveniently, safely.
It above are only presently preferred embodiments of the present invention, but the present invention is not restricted to above-described embodiment, be familiar with this field Technical staff can also make a variety of equivalent deformation or replacement on the premise of without prejudice to spirit of the invention, these equivalent deformations Or replacement is all included in the scope defined by the claims of the present application.

Claims (24)

1. a kind of flash detecting device, it is characterised in that: including cabinet, darkroom, scintillation detector and objective table, the darkroom, The scintillation detector and the objective table are mounted in the cabinet;
The darkroom is provided with the first opening, the end of probe of the scintillation detector and first open butt joint;
The second opening is additionally provided on the darkroom, the objective table passes in and out the darkroom, the load by second opening The carrying position for carrying sample to be tested or sample loading attachment is provided on object platform, the objective table is located in the darkroom When, the carrying position and first opening are opposite;
The position that second opening is corresponded on the cabinet is provided with hatch, and the objective table passes through described in hatch disengaging Cabinet.
2. flash detecting device according to claim 1, it is characterised in that: the scintillation detector includes photomultiplier transit Pipe;First opening is set to the top surface in the darkroom, and the photomultiplier tube is vertically installed at the top in the darkroom, described The cathode terminal of photomultiplier tube and first open butt joint;When the objective table is located in the darkroom, the carrying position is right The lower section of first opening described in Ying Yu.
3. flash detecting device according to claim 1, which is characterized in that the carrying position is equipped with for carrying to test sample The mounting groove of product or the sample loading attachment.
4. flash detecting device according to claim 1, it is characterised in that: the bottom of the cabinet is fixedly installed first Mounting rack, the darkroom are fixedly mounted on first mounting rack.
5. flash detecting device according to claim 1, it is characterised in that: the bottom of the cabinet is fixedly installed first Mounting rack, a cover is fixedly installed on first mounting rack, and the cover and first mounting rack surround described jointly Darkroom.
6. flash detecting device according to claim 1, it is characterised in that: further include power device and transmission device, institute The lower section that power device is fixedly installed in the darkroom is stated, the inside in the darkroom, the darkroom is arranged in the transmission device Offer third opening, the power device is open by the third and is connect with the transmission device, the transmission device and The objective table connection.
7. flash detecting device according to claim 6, it is characterised in that: the transmission device includes rack and pinion, The rack gear is fixedly connected with the objective table, and the gear is set on the output shaft of the power device, the gear with The rack gear engagement.
8. flash detecting device according to claim 1, it is characterised in that: further include slide track component, the objective table is logical The slide track component is crossed to be slidably connected with the darkroom.
9. flash detecting device according to claim 8, it is characterised in that: the slide track component includes sliding rail, the first peace Fill item and the second mounting bar, first mounting bar is fixedly connected on the bottom surface in the darkroom, second mounting bar with it is described Objective table is fixedly connected;First mounting bar is fixed or be slidably connected to the sliding rail, and second mounting bar is slidably connected In the sliding rail.
10. flash detecting device according to claim 1, it is characterised in that: it further include scanning means, the scanning means It is fixedly installed in the lower section in the darkroom, the position that the darkroom corresponds to the scanning means offers the 4th opening.
11. flash detecting device according to claim 1, it is characterised in that: the cabinet is internally provided with the second peace It shelves, second mounting rack is located at the top in the darkroom, and the scintillation detector is fixedly mounted on second mounting rack On.
12. flash detecting device according to claim 11, it is characterised in that: be provided with fixation on second mounting rack Seat and supporting plate are provided with fixing groove in the fixing seat, and the supporting plate is fixedly mounted on the fixing seat, the supporting plate and institute It is circumferentially fixed to the outer wall progress of the photomultiplier tube to state fixing groove.
13. flash detecting device according to claim 11, it is characterised in that: it further include power supply device, the power supply dress It sets and is fixedly mounted on second mounting rack or the cabinet.
14. flash detecting device according to claim 1, it is characterised in that: be provided with display dress on front side of the cabinet It sets, control module is equipped in the cabinet, the display device and the scintillation detector are electrically connected with the control module respectively It connects.
15. flash detecting device according to claim 14, it is characterised in that: the front side of the cabinet includes one from forward direction The mounting portion of rear-inclined, the display device are fixedly installed on the mounting portion, and the control module is set to the display dress The back set.
16. flash detecting device according to claim 1, it is characterised in that: the bottom of the cabinet offers blow vent, The top of the cabinet offers exhaust outlet, and the exhaust ports are provided with exhaust apparatus.
17. flash detecting device according to claim 1, it is characterised in that: the cabinet includes boxboard, and the hatch is opened It is located on the boxboard, the baffle for closing hatch is provided at the hatch, the baffle is rotatably connected to described At hatch.
18. flash detecting device according to claim 17, it is characterised in that: the hatch periphery is provided with from the case The installation groove that the outer surface of plate is recessed inwardly, the position that the inside of the baffle corresponds to the installation groove are provided with fin, When the baffle closes the hatch, the fin is located in the installation groove.
19. flash detecting device according to claim 1, it is characterised in that: the end of probe of the scintillation detector with into X-ray excited polycrystalline structure scintillator is provided between sample to be tested after entering the darkroom.
20. flash detecting device according to claim 19, it is characterised in that: the X-ray excited polycrystalline structure scintillator is set to the sudden strain of a muscle At the end of probe of bright detector.
21. flash detecting device according to claim 19, it is characterised in that: the solid scintillator be attached to it is described to Sample.
22. flash detecting device according to claim 19, it is characterised in that: the sample loading attachment, which is provided with, to be used for The loading chute of sample to be tested is loaded, the X-ray excited polycrystalline structure scintillator is set at the notch of the loading chute.
23. flash detecting device according to claim 22, it is characterised in that: the sample loading attachment, which is equipped with, blows Mouthful, inlet channel and outlet passageway, the inflatable mouth, the inlet channel, the loading chute and the outlet passageway successively phase It is logical.
24. flash detecting device according to claim 22, it is characterised in that: the X-ray excited polycrystalline structure scintillator is solid-state flashing Film, the solid-state flashing film are attached at the notch of the loading chute.
CN201811522483.6A 2018-12-12 2018-12-12 Scintillation detection device Active CN109655478B (en)

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