CN109481351A - A kind of preparation method of compound plant channels and network vessels regulation oil - Google Patents

A kind of preparation method of compound plant channels and network vessels regulation oil Download PDF

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Publication number
CN109481351A
CN109481351A CN201811497962.7A CN201811497962A CN109481351A CN 109481351 A CN109481351 A CN 109481351A CN 201811497962 A CN201811497962 A CN 201811497962A CN 109481351 A CN109481351 A CN 109481351A
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essential oil
oil
parts
preparation
channels
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CN109481351B (en
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史学东
陈波
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GUANGZHOU DEVA BIOTECHNOLOGY Co Ltd
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GUANGZHOU DEVA BIOTECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract

The present invention provides a kind of preparation method of compound plant channels and network vessels regulation oil, is made of following parts by weight ingredient: olive oil, wheat-germ oil, cinnamon essential oil, ginger essential oil, angelica essential oil, pepper essential oil, Rehmannia glutinosa essential oil, olibanum essential oil, Rhizoma Et Radix Notopterygii essential oil, fructus lycii essential oil, capsicum oil;Plant meridian of the invention improves oil, easily permeates, easily absorbs, has activating microcirculation and removing stasis medicinal, dredging the channel and other effects;Phenomena such as pure herbaceous plant compound, preservative free safely and effectively get rid of illness, scattered stasis detumescence suitable for channels and collaterals health, channels and collaterals, effective dredging the channel, alleviation arthralgia, dissipation redness and swelling of joints;Make skin that there is certain anti-aging ability;Preparation is easy, and is suitble to extensive continuous industrial production.

Description

A kind of preparation method of compound plant channels and network vessels regulation oil
Technical field
The invention belongs to cosmetic fields, and in particular to a kind of preparation method of compound plant channels and network vessels regulation oil.
Background technique
With social development and improvement of living standard, people increasingly pay attention to health, and especially massage class essential oil is supported It is raw.Modern is often associated with mental output frequently, consumes a large amount of physical functions, another party looks unfamiliar since work and study pressure is big Tempo increase living, diet is irregular and does not arrange in pairs or groups unreasonable, makes so to lead to gastrointestinal disturbances system disorders for a long time, can not normally provide The energy of general consumption, in another aspect, in most cases long-term sitting, does not get enough athletic exercise, often will appear and have a pain in the back, neck Shoulder such as is ached at the symptoms, and long-term such vertebra or even femoral head junction are prone to wear, and eventually leads to limb motion inconvenience, band More to bother.The present invention is a kind of compound plant essential oil, and no added preservative can reach by way of therapeutic massage Organism fatigue is mitigated or eliminated, improves shoulder neck discomfort, back acid is swollen equal sub-health status, and there is good happy whole body warp Network, help restore physical function, reach balance, improve self-healing ability.
Summary of the invention
First purpose of the invention provides a kind of compound plant channels and network vessels regulation oil.
Another object of the present invention is to provide a kind of preparation method of compound plant channels and network vessels regulation oil.
It is also another object of the present invention to provide the manner of packings that a kind of plants essential oil high activity saves.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of compound plant channels and network vessels regulation oil, is made: 55~70 parts of olive oil, wheat-germ oil of following parts by weight ingredient 10~30 parts, 1~10 part of cinnamon essential oil, 1~8 part of ginger essential oil, 1~8 part of angelica essential oil, 1~5 part of pepper essential oil, Rehmannia glutinosa 1~4 part of essential oil, 1~4 part of olibanum essential oil, 0.5~3 part of Rhizoma Et Radix Notopterygii essential oil, 0.5~3 part of fructus lycii essential oil, 0.1~3 part of capsicum oil.
It is highly preferred that being made of following parts by weight ingredient: 60~66 parts of olive oil, 15~25 parts of wheat-germ oil, cortex cinnamomi 2~5 parts of essential oil, 1~5 part of ginger essential oil, 1~5 part of angelica essential oil, 1~4 part of pepper essential oil, 1~3 part of Rehmannia glutinosa essential oil, olibanum 1~3 part of essential oil, 1.0~2.5 parts of Rhizoma Et Radix Notopterygii essential oil, 1.0~2.5 parts of fructus lycii essential oil, 0.5~2 part of capsicum oil.
Most preferably, be made of following parts by weight ingredient: 63 parts of olive oil, 20 parts of wheat-germ oil, 3 parts of cinnamon essential oil, 2.5 parts of ginger essential oil, 2 parts of angelica essential oil, 2 parts of pepper essential oil, 2 parts of Rehmannia glutinosa essential oil, 1.5 parts of olibanum essential oil, Rhizoma Et Radix Notopterygii essential oil 1.5 Part, 1.5 parts of fructus lycii essential oil, 1 part of capsicum oil.
A kind of preparation method of compound plant channels and network vessels regulation oil described in any of the above embodiments, comprising the following steps:
S1: olive oil, wheat-germ oil, cinnamon essential oil, angelica essential oil, radix rehmanniae preparata rhizoma polygonati are added into the container sterilized Oil, olibanum essential oil, Rhizoma Et Radix Notopterygii essential oil, fructus lycii essential oil, are sufficiently stirred;
S2: continuously adding ginger essential oil, pepper essential oil, capsicum oil in S1, be sufficiently stirred, form uniform mixed liquor, Oil is improved up to the plant meridian.
Preferably, mixing speed is 10~25RPM in step S1.
Preferably, mixing time is 10~20min in step S1.
Preferably, mixing speed is 5~20RPM in step S2.
Preferably, mixing time is 5~15min in step S2.
Preferably, ampulla described in S3 is a kind of hard glass container that can be sealed, and is usually used in storing injection
Drug and vaccine, serum etc..
Preferably, ampulla silicon content described in S3 is 7.5%~10.0%.
Preferably, the upper half of the ampulla fracture and lower half ratio are 1:2~1:1, and preferably the upper half is under Half portion ratio is 0.71:1.
Preferably, it is 40N~60N that the ampulla, which breaks disconnected power size, and preferably ampulla breaks disconnected power size 50N.
Preferably, it is 0.1mm~1.0mm that the ampulla, which breaks the fracture batch cutting edge of a knife or a sword height after breaking, preferably fracture batch cutting edge of a knife or a sword Highly 0.3~0.6mm, more preferably fracture batches of cutting edge of a knife or a sword height are 0.4mm.
Cinnamon essential oil, ginger essential oil, Rehmannia glutinosa essential oil (Jiangxi Heng Cheng pharmaceutcal corporation, Ltd HC-1203, HC-1506, HC- 1604)
Compared with existing channels and network vessels regulation oil cosmetic product, the invention has the following beneficial effects: (1) to provide a kind of safety Effective channels and network vessels regulation oil, various plants essential oil recombination energy effectively excite body metabolism, wherein the cinnamon essential oil added and Angelica essential oil can more promote cell to grow, and improve body self-healing ability.(2) a kind of active high-effect preservation side of plants essential oil is provided Formula.Ampulla is to apply the relatively effective mode for saving drug, effective component in medicine that can be existed by safe preservation, advantage In, using the inert gases such as nitrogen use controlled atmosphere technology, completely cut off air in oxygen, reach hypoxemia even anaerobic ring Border enables the effective active matter in ampulla effectively to be saved, and guarantees that it still has high activity when in use.
Detailed description of the invention
Fig. 1 is the schematic diagram after ampulla of the present invention sealing.
Specific embodiment
Below in conjunction with specific embodiment, the invention will be further described, but embodiment does not do any form to the present invention Restriction.Unless stated otherwise, the present invention uses reagent, method and apparatus for the art conventional reagent, method and are set It is standby.
Unless stated otherwise, reagent and material used in following embodiment are commercially available.
Embodiment 1
A kind of preparation method of compound plant channels and network vessels regulation oil bottle, is followed these steps to be prepared by following raw material It arrives:
63 parts of olive oil, 20 parts of wheat-germ oil, 3 parts of cinnamon essential oil, angelica essential oil 2 are added into the container sterilized by S1 Part, 2 parts of Rehmannia glutinosa essential oil, 1.5 parts of olibanum essential oil, 1.5 parts of Rhizoma Et Radix Notopterygii essential oil, 1.5 parts of fructus lycii essential oil, mixing speed 10RPM, sufficiently Stir 10min;
S2: continuously adding 2.5 parts of ginger essential oil, 2 parts of pepper essential oil, 1 part of capsicum oil in S1, mixing speed 5RPM, 5min is sufficiently stirred, forms uniform mixed liquor to get the plant meridian conditioning oil;
S3: filling, packaging.
Channels and network vessels regulation oil of the present invention is packaged preservation (see Fig. 1) using ampulla, and ampulla is a kind of hard glass that can be sealed Glass container, ampulla silicon content 8.9%, the preferably upper half and lower half ratio are 0.618:1, and ampulla breaks disconnected power size 45N, are broken Mouth batch cutting edge of a knife or a sword height is 0.5mm.
Embodiment 2
A kind of preparation method of compound plant channels and network vessels regulation oil, is followed these steps to be prepared by following raw material:
63 parts of olive oil, 17 parts of wheat-germ oil, 4 parts of cinnamon essential oil, angelica essential oil 3 are added into the container sterilized by S1 Part, 3 parts of Rehmannia glutinosa essential oil, 1.5 parts of olibanum essential oil, 1.5 parts of Rhizoma Et Radix Notopterygii essential oil, 1.5 parts of fructus lycii essential oil, mixing speed 25RPM, sufficiently Stir 20min;
S2: continuously adding 2.5 parts of ginger essential oil, 2 parts of pepper essential oil, 1 part of capsicum oil in S1, mixing speed 20RPM, 15min is sufficiently stirred, forms uniform mixed liquor to get the plant meridian conditioning oil;
S3: filling, packaging.
Embodiment 3
A kind of preparation method of compound plant channels and network vessels regulation oil, is followed these steps to be prepared by following raw material:
62 parts of olive oil, 20 parts of wheat-germ oil, 3 parts of cinnamon essential oil, angelica essential oil 3 are added into the container sterilized by S1 Part, 3 parts of Rehmannia glutinosa essential oil, 1.5 parts of olibanum essential oil, 1.5 parts of Rhizoma Et Radix Notopterygii essential oil, 1.5 parts of fructus lycii essential oil, mixing speed 25RPM, sufficiently Stir 20min;
S2: continuously adding 2.5 parts of ginger essential oil, 1 part of pepper essential oil, 1 part of capsicum oil in S1, mixing speed 10RPM, 20min is sufficiently stirred, forms uniform mixed liquor to get the plant meridian conditioning oil;
S3: filling, packaging.
Embodiment 4
A kind of preparation method of compound plant channels and network vessels regulation oil, is followed these steps to be prepared by following raw material:
655 parts of olive oil, 10 parts of wheat-germ oil, 1 part of cinnamon essential oil, angelica essential oil are added into the container sterilized by S1 1 part, 1 part of Rehmannia glutinosa essential oil, 1 part of olibanum essential oil, 0.5 part of Rhizoma Et Radix Notopterygii essential oil, 0.5 part of fructus lycii essential oil, mixing speed 10RPM, sufficiently Stir 10min;
S2: continuously adding 1 part of ginger essential oil, 1 part of pepper essential oil, 0.1 part of capsicum oil in S1, mixing speed 5RPM, 5min is sufficiently stirred, forms uniform mixed liquor to get the plant meridian conditioning oil;
S3: filling, packaging.
Embodiment 5
A kind of preparation method of compound plant channels and network vessels regulation oil, is followed these steps to be prepared by following raw material:
70 parts of olive oil, 30 parts of wheat-germ oil, 10 parts of cinnamon essential oil, angelica essential oil are added into the container sterilized by S1 8 parts, 4 parts of Rehmannia glutinosa essential oil, 4 parts of olibanum essential oil, 3 parts of Rhizoma Et Radix Notopterygii essential oil, 3 parts of fructus lycii essential oil, mixing speed 25RPM are sufficiently stirred 20min;
S2: continuously adding 8 parts of ginger essential oil, 5 parts of pepper essential oil, 3 parts of capsicum oil in S1, and mixing speed 20RPM fills Divide stirring 15min, forms uniform mixed liquor to get the plant meridian conditioning oil;
S3: filling, packaging.
Embodiment 6
A kind of preparation method of compound plant channels and network vessels regulation oil, is followed these steps to be prepared by following raw material:
60 parts of olive oil, 15 parts of wheat-germ oil, 2 parts of cinnamon essential oil, angelica essential oil 1 are added into the container sterilized by S1 Part, 1 part of Rehmannia glutinosa essential oil, 1 part of olibanum essential oil, 1.0 parts of Rhizoma Et Radix Notopterygii essential oil, 1.0 parts of fructus lycii essential oil, mixing speed 20RPM are sufficiently stirred Mix 15min;
S2: continuously adding 1 part of ginger essential oil, 1 part of pepper essential oil, 0.5 part of capsicum oil in S1, mixing speed 20RPM, 15min is sufficiently stirred, forms uniform mixed liquor to get the plant meridian conditioning oil;
S3: filling, packaging.
Embodiment 7
A kind of preparation method of compound plant channels and network vessels regulation oil, is followed these steps to be prepared by following raw material:
43.5 parts of olive oil, 25 parts of wheat-germ oil, 5 parts of cinnamon essential oil, tanquedate are added into the container sterilized by S1 Oily 5 parts, 3 parts of Rehmannia glutinosa essential oil, 3 parts of olibanum essential oil, 2.5 parts of Rhizoma Et Radix Notopterygii essential oil, 2.5 parts of fructus lycii essential oil, mixing speed 25RPM fill Divide stirring 20min;
S2: continuously adding 5 parts of ginger essential oil, 4 parts of pepper essential oil, 2 parts of capsicum oil in S1, and mixing speed 20RPM fills Divide stirring 15min, forms uniform mixed liquor to get the plant meridian conditioning oil;
S3: filling, packaging.
Reference examples 1
A kind of preparation method of compound plant channels and network vessels regulation oil, is followed these steps to be prepared by following raw material:
68 parts of olive oil, 20 parts of wheat-germ oil, 2 parts of Rehmannia glutinosa essential oil, olibanum essence are added into the container sterilized by S1 20min is sufficiently stirred in oily 1.5 parts, 1.5 parts of Rhizoma Et Radix Notopterygii essential oil, 1.5 parts of fructus lycii essential oil, mixing speed 25RPM;
S2: continuously adding 2.5 parts of ginger essential oil, 2 parts of pepper essential oil, 1 part of capsicum oil in S1, mixing speed 20RPM, 15min is sufficiently stirred, forms uniform mixed liquor to get the plant meridian conditioning oil;
S3: filling, packaging.
Product effect
1. volunteer selects
1) age between 32 years old to 65 years old, 13 volunteers;
2) other drugs were not taken up to 1 week or more.
3) no less than 1500 milliliters of water is drunk during use as far as possible.
2. product application method
Volunteer's application 1 product of embodiment prepared by the present invention daily 1~2 time, is applied with sooner or later on using area surface, And it is massaged into absorption;Use 20~30 days observing effects.
3. gout clinical examination
The observation of symptom and sign: arthralgia, articular pain, the acute redness in joint, joint movement disorder.
(1) arthralgia
0 grade (0 point): without pain;
1~3 grade (1 point): mild pain, but still normal activity can be engaged in;
4~6 grades (2 points): moderate pain influences work, but can take care of oneself;
7~9 grades (3 points): severe pain be can't take care of oneself:
10 grades (4 points): severe pain can not be endured.
(2) articular pain
0 point: without tenderness;
1 point: pressure tells pain;
2 points: pressure tells that pain companion frowns;
3 points: pressure tells that pain is shunk back with joint.
(3) the acute redness in joint
0 point: skin is without redness;
1 point: local skin is slightly red;
2 points: local skin is slightly red, and joint is relatively slightly swollen before the onset;
3 points: local skin is obvious rubescent hot, and joint is with apparent acute swelling;
(4) joint movement disorder
0 point: activity is without limited;
1 point: activity moderate is limited, but still can be engaged in normal activity;
2 points: activity is obvious limited, cannot be engaged in general activity, but can take care of oneself;
3 points: activity is in great pain, and bed be can't take care of oneself.
(1) (2) (3) and (4) four part scores add up to total mark, and minimum 0 point, up to 13 points, total mark is higher It indicates and more serious.According to patient symptom, the suppression ratio of sign total mark, it is divided into clinical recovery, effective, effective and invalid four A grade.Pretherapy and post-treatment effect is as shown in table 1, and different product treated effect statistics is as shown in table 2.
Recovery from illness: arthralgia, tenderness, acute red and swollen, limitation of activity total mark decline 100%.
It is effective: arthralgia, tenderness, acute red and swollen, limitation of activity total mark decline >=66%.
Effective: arthralgia, tenderness, acute red and swollen, limitation of activity total mark decline >=33% and < 66%.It is invalid: Arthralgia, tenderness, acute red and swollen, limitation of activity total mark decline < 33%.
Note: integral reduces percentage=(one post treatment integral of pre-treatment score)/pre-treatment score × 100%.
Table 1 uses the articular conditions before and after the present embodiment product
Table 2 is counted using the present embodiment effective percentage
According to Tables 1 and 2 it is found that using product manufactured in the present embodiment, the arthralgia of volunteer, articular pain, pass Section is red and swollen and joint movement disorder scoring decline is significant, and using after product of the present invention, pain index is reduced the patient of severe pain To moderate or mild pain, living less influences.And for comprehensive therapeutic effect, using effective percentage of the invention reach 80% with On, effective percentage up to 92.31%, much higher than the 31.25% of reference examples.
By largely testing discovery, selected various plants essential oil is applied in combination, can effectively improve, work and study it Feeling of fatigue afterwards increases organism metabolism, reinforces self-healing ability, improves sleep state.
Using natural plant essential oils as raw material, there is dredging the channel, improve joint part pain discomfort, improve body self-healing energy Power makes skin have certain anti-aging ability.And by the way of various plants essential oil combination collocation, to reach more preferably Fatigue of releiving, dredge the effect of whole body meridian.Plants essential oil is absorbed after massaging through skin surface, into subcutaneous group It knits, active cell differentiation capability, accelerates self-renewing, improve body self-healing ability, enhance anti-aging ability.

Claims (10)

1. a kind of compound plant channels and network vessels regulation oil, which is characterized in that be made of following parts by weight ingredient: 55~70 parts of olive oil, 10~30 parts of wheat-germ oil, 1~10 part of cinnamon essential oil, 1~8 part of ginger essential oil, 1~8 part of angelica essential oil, pepper essential oil 1~5 Part, 1~4 part of Rehmannia glutinosa essential oil, 1~4 part of olibanum essential oil, 0.5~3 part of Rhizoma Et Radix Notopterygii essential oil, 0.5~3 part of fructus lycii essential oil, capsicum oil 0.1~3 part.
2. a kind of compound plant channels and network vessels regulation oil according to claim 1, which is characterized in that by following parts by weight ingredient system At: 60~66 parts of olive oil, 15~25 parts of wheat-germ oil, 2~5 parts of cinnamon essential oil, 1~5 part of ginger essential oil, angelica essential oil 1 ~5 parts, 1~4 part of pepper essential oil, 1~3 part of Rehmannia glutinosa essential oil, 1~3 part of olibanum essential oil, 1.0~2.5 parts of Rhizoma Et Radix Notopterygii essential oil, fructus lycii 1.0~2.5 parts of essential oil, 0.5~2 part of capsicum oil.
3. a kind of compound plant channels and network vessels regulation oil according to claim 1, which is characterized in that by following parts by weight ingredient system At: 63 parts of olive oil, 20 parts of wheat-germ oil, 3 parts of cinnamon essential oil, 2.5 parts of ginger essential oil, 2 parts of angelica essential oil, pepper essential oil 2 Part, 2 parts of Rehmannia glutinosa essential oil, 1.5 parts of olibanum essential oil, 1.5 parts of Rhizoma Et Radix Notopterygii essential oil, 1.5 parts of fructus lycii essential oil, 1 part of capsicum oil.
4. a kind of described in any item preparation methods of compound plant channels and network vessels regulation oil of claims 1 to 3, which is characterized in that packet Include following steps:
S1: olive oil, wheat-germ oil, cinnamon essential oil, angelica essential oil, Rehmannia glutinosa essential oil, cream are added into the container sterilized Essential oil, Rhizoma Et Radix Notopterygii essential oil, fructus lycii essential oil, are sufficiently stirred;
S2: continuously adding ginger essential oil, pepper essential oil, capsicum oil in S1, forms uniform mixed liquor to get the plant Channels and network vessels regulation oil;
S3: preservation is packaged using ampulla.
5. the preparation method according to claim 4, which is characterized in that mixing speed is 10~25RPM in step S1.
6. the preparation method according to claim 4, which is characterized in that mixing time is 10~20min in step S1.
7. the preparation method according to claim 4, which is characterized in that mixing speed is 5~20RPM in step S2.
8. the preparation method according to claim 4, which is characterized in that mixing time is 5~15min in step S2.
9. the preparation method according to claim 4, which is characterized in that ampulla described in S3 is a kind of hard glass that can be sealed Glass container is usually used in storing drug and vaccine, serum of injection etc..
10. the preparation method according to claim 4, which is characterized in that ampulla silicon content described in S3 be 7.5%~ 10.0%.
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