CN106177437B - Maca composition for improving yang deficiency and body cold of women - Google Patents

Abstract

The invention discloses a maca composition for improving yang deficiency and body cold of women, which comprises the following raw materials in percentage by weight: 35-55% of maca, 5-15% of ginseng, 3-10% of cinnamon, 1-10% of wolfberry, 2-10% of Chinese yam, 3-10% of sweet osmanthus, 0.5-5% of lily, 1-7% of polygonatum odoratum, 0.3-5% of lotus leaf, 1-6% of licorice and the balance of auxiliary materials. The formula is based on the theory of conditioning female bodies by traditional Chinese medicine, refers to modern pharmacological research, and takes the therapeutic principles of tonifying kidney and spleen, tonifying qi and yang, relaxing channels and relieving pain, promoting blood circulation and removing blood stasis, nourishing liver and kidney, moistening lung and nourishing yin by synergistic compounding of all the medicines, and conditions by soothing liver and regulating qi, removing blood stasis and dissipating stagnation so as to achieve the effects of removing in-vivo metabolic stasis and balancing female qi and blood, thereby improving the constitution of the female with yang deficiency and body cold. The maca composition disclosed by the invention is good in absorption effect, long in drug effect duration, remarkable in curative effect, convenient to take, free of side effect, high in safety, simple to prepare, low in production cost and beneficial to timely alleviating symptoms of patients.

Description

Maca composition for improving yang deficiency and body cold of women

Technical Field

The invention belongs to the field of health care products, and particularly relates to a maca composition for improving yang deficiency and body cold of women.

Background

Modern women are more vulnerable to exogenous pathogenic factors such as wind, cold, summer heat, dampness and the like than other people due to the double pressure of shoulder burden in families and work, and are caused by the constitution of yang deficiency and body cold. Yang deficiency constitutions are constitutional states characterized mainly by deficiency-cold due to insufficiency of yang qi in the body. Yang qi can warm the limbs and viscera, and if yang deficiency occurs, the body functions are reduced, which is easy to cause symptoms of deficiency-cold, such as stomach yang deficiency, spleen yang deficiency, kidney yang deficiency, etc. The main clinical manifestations of yang deficiency are aversion to cold, cold limbs, white complexion, loose stools, clear and profuse urine, deep and weak pulse, persistent abdominal pain, persistent time, preference for heat and aversion to cold, press-feeling when pain is felt, hunger or aggravation after fatigue, accompanied by aversion to cold, cold limbs, soreness and weakness of waist and knees, easy cold, etc. The body cold syndrome is caused by hormone secretion disorder, abnormal vasoconstriction and dilation and blood circulation function reduction, so that the body temperature regulation can not be normally carried out. The traditional Chinese medicine is called 'qi-blood disharmony', particularly, hormones of women are often disordered before and after a menstrual period, so that the body temperature is easy to drop in the period. The cold body is easy to cause abnormal 'blood' in the body, thereby causing diseases such as irregular menstruation, endometrium, hysteromyoma and the like. Meanwhile, the abnormal water in the body can be caused, so that headache, dizziness, edema and constipation are caused, and the symptoms of uneasiness, dysphoria, insomnia and the like are probably caused by unsmooth qi. Therefore, people with cold constitutions should heavily tonify yang qi.

The traditional Chinese medicine considers that the kidney is the root of the collection, mainly stores essence, and the innate essence and the acquired essence are stored in the kidney, so that the essence and the acquired essence mutually promote and generate primordial qi, and the primordial qi is the root of life. After qi transformation, the qi circulates through the three jiao to disperse the five zang-organs and six fu-organs, so as to stimulate, promote and coordinate the viscera and meridians to participate in the generation and circulation of qi and blood. The yang qi in the kidney is the sun of the body, is the fire of life, and the food ingested by the human body is transformed into qi and blood by means of the transportation and transformation of the spleen, the digestion and the decomposition of the stomach, and the purification and the secretion of the small intestine under the transpiration and gasification of the kidney yang, and the qi and the blood are distributed to various organs through the meridian system all over the body, thereby continuously providing power and capability for life. Therefore, to improve the constitution of yang deficiency and cold body, the spleen and kidney should be adjusted and tonified, and the yang of spleen and kidney should be warmed and tonified. Some people regulate through exercise and some people regulate through diet, which are good methods, but the expected effect is difficult to achieve, if people accumulate for a long time, various gynecological diseases which are difficult to cure are easily induced, and the physical health of women is seriously affected.

Disclosure of Invention

The invention aims to overcome the defects in the prior art and provides the maca composition which is good in curative effect and low in toxic and side effects and can improve yang deficiency and body cold of women.

The above object of the present invention is achieved by the following means.

The maca composition for improving yang deficiency and body cold of women is prepared from the following raw materials in percentage by weight: 35-55% of maca, 5-15% of ginseng, 3-10% of cinnamon, 1-10% of wolfberry, 2-10% of Chinese yam, 3-10% of sweet osmanthus, 0.5-5% of lily, 1-7% of polygonatum odoratum, 0.3-5% of lotus leaf, 1-6% of licorice and the balance of auxiliary materials.

The traditional medical research in China considers that the treatment of the yang deficiency and the body cold of women generally starts from tonifying the kidney, strengthening the spleen, soothing the liver and regulating the flow of qi. The traditional Chinese medicine considers that menstrual fluid flows out of the kidney, so that the menstruation can be regulated by tonifying the kidney, the kidney is mainly used for filling essence and blood, and after regulation, the kidney qi is sufficient, the essence and blood are vigorous, the menstruation is regulated, and the qi and the blood are naturally smooth. The spleen functions to generate blood and tonify spleen and stomach to replenish the blood source of body. The spleen-strengthening method mainly aims at strengthening the spleen and invigorating yang, while the purpose of soothing the liver and regulating qi is to regulate qi movement and dredge qi and blood. The maca composition capable of remarkably improving yang deficiency and body cold of women is obtained by synergistic compounding of the components based on the theory of conditioning female bodies by traditional Chinese medicine and referring to modern pharmacological research, has the effects of preventing and improving yang deficiency and body cold, tonifying kidney and spleen, tonifying qi and benefiting yang, activating blood and dredging collaterals, relaxing channels and relieving pain, moistening lung and nourishing yin and delaying aging, can condition female endocrine, eliminate in-vivo metabolic stasis, balance female qi and blood, recover the endocrine system to normal operation, and effectively relieve symptoms such as dysmenorrheal, cold hands and feet, cold womb, cold sensation, breast gall, palpitation and short breath, fatigue, poor sleep quality, neurasthenia, hypomnesis, lusterless complexion, freckles, tiredness of bodies and the like caused by endocrine dyscrasia.

The maca food is a food therapy formula, and maca in the formula is pungent, slightly spicy and warm in nature, can warm kidney and tonify yang to dispel cold and rescue adverse qi, and can pass through twelve meridians to stimulate yang of the whole body; ginseng is a monarch drug which can tonify primordial qi, relieve depletion and promote the production of body fluid, regulate middle-jiao and treat qi, smooth blood vessels and nourish primordial yang; cinnamon, medlar and yam have the effects of supplementing fire and supporting yang, guiding fire to the origin, dispelling cold and relieving pain, promoting blood circulation and stimulating the menstrual flow, nourishing liver and kidney, tonifying spleen and nourishing stomach, promoting the production of body fluid and benefiting lung, tonifying kidney and arresting seminal emission, sweet osmanthus has the effects of dispelling cold and qi, removing blood stasis and enhancing yang recovery, and is a ministerial drug; the lily is sweet and slightly cold in nature, has the effects of nourishing yin, moistening lung, clearing away the heart fire, soothing the nerves, and nourishing yin, moistening dryness, promoting the production of body fluid, quenching thirst, clearing away summer heat, promoting hair growth, clearing yang, and assisting the warmth and dryness of the maca and the cinnamon, and is an adjuvant drug; licorice root, radix Glycyrrhizae is sweet and mild, regulates the middle-warmer and relieves urgency, warms yang qi, and can coordinate the effects of the other drugs in the recipe. Only when the components are reasonably compounded according to the weight percentage, the aim of mutual synergy can be achieved.

Maca (Maca) is pungent in taste, slightly spicy and warm in nature, enters lung and kidney meridians, has the effects of tonifying kidney yang, benefiting essence and blood and the like as a medicine and food dual-purpose plant, is rich in various amino acids, active enzymes, mineral substances, trace elements and physiologically active secondary metabolites required by a human body, can regulate the balance of yin and yang of the human body, promotes blood circulation, nourishes yin and yang, and effectively prevents and improves yang deficiency and body cold. Traditionally, maca is used to improve fertility, resist fatigue, enhance physical strength, improve sexual function, regulate endocrine system, balance hormones, resist anemia, relieve female climacteric syndrome, resist rheumatic arthritis, and the like.

Ginseng, radix Ginseng, sweet in taste and slightly bitter in taste, is slightly warm and not dry, enters spleen and lung channels, is neutralized by nature, has the effects of invigorating primordial qi, tonifying spleen and lung, nourishing blood and promoting fluid production, tranquilizing and benefiting intelligence, and widely benefits five internal organs, is the first essential medicine for treating consumptive disease and internal injury, and can be used for treating various deficiency syndromes. The main treatment is as follows: asthenia and desire to loose, cold limbs and little pulse, spleen deficiency and anorexia, lung deficiency and cough with dyspnea, body fluid deficiency and thirst, internal heat and thirst, deficiency with asthenia for a long time, palpitation and insomnia, impotence and cold womb, heart failure, cardiogenic shock; can be used for treating short breath, dyspnea, palpitation, amnesia, thirst, hyperhidrosis, anorexia, asthenia, acute and chronic diseases, and shock and collapse caused by blood loss; it is indicated for deficiency due to overstrain, poor appetite, lassitude, regurgitation, diarrhea, cough, dyspnea, spontaneous sweating, palpitation, amnesia, vertigo, headache, impotence, frequent micturition, diabetes, metrorrhagia, metrostaxis, chronic infantile convulsion, and deficiency of both qi and blood.

Cinnamon, pungent and sweet in nature and flavor, with great heat, enters kidney, spleen, heart and liver channels, and has the effects of tonifying fire and supporting yang, guiding fire to the source, dispelling cold and relieving pain, and activating blood and stimulating menstrual flow. Can be used for treating sexual impotence, cold womb, psychroalgia of waist and knee, asthma due to kidney deficiency, vertigo due to yang deficiency, conjunctival congestion, pharyngalgia, psychroalgia of heart and abdomen, vomiting and diarrhea due to deficiency cold, cold hernia, dolphin, amenorrhea, and dysmenorrhea.

The medlar has sweet and mild nature and taste, enters the liver channel and the stomach channel, enters the lung channel, and has the functions of tonifying the kidney and replenishing vital essence, nourishing the liver to improve eyesight, enriching the blood and soothing the nerves, promoting the production of body fluid to quench thirst, moistening the lung and relieving cough. It is indicated for apoplexy, dizziness and consumptive disease, which are manifested as blood syndrome, cough with blood, flaccidity, syncope, contracture, miasma, injury with dryness, seminal emission, reddish turbidity, beriberi and crane-knee wind.

The Chinese yam is sweet in nature and taste, is neutral, enters spleen, lung and kidney channels, and has the effects of tonifying spleen and lung, reinforcing stomach and kidney, reinforcing kidney and replenishing vital essence, improving hearing and eyesight, assisting five internal organs, strengthening bones and muscles, promoting mind and calming nerves and prolonging life; it can be used for treating weakness of spleen and stomach, asthenia, anorexia, chronic diarrhea, dysentery, dryness of lung-qi, phlegm asthma, cough, deficiency of kidney-qi, soreness of waist and knees, asthenia, thirst, frequent micturition, spermatorrhea, premature ejaculation, leukorrhagia, red swelling of skin, and obesity.

Osmanthus fragrans flower, pungent in nature and flavor and warm in nature, enters spleen, lung and kidney meridians. The functional indications are as follows: dispel cold and break accumulation, amenorrhea and abdominal pain. Disperse cold qi, clear stasis and blood.

The lily is sweet and cold in nature and flavor, enters heart and lung channels, has the effects of nourishing yin and moistening lung, moistening dryness and clearing heat, clearing away heart fire and soothing nerves, and maintaining beauty and keeping young, and is used for treating chronic cough due to yin deficiency, bloody sputum, dysphoria with pavor, insomnia and dreaminess, absent mindedness, cough due to lung dryness and dysphoria.

Yu Zhu is sweet in flavor and neutral in nature and enters lung and stomach meridians. The functional indications are as follows: has effects in nourishing yin, moistening lung, nourishing stomach, and promoting fluid production, and can be used for treating dry cough, chronic cough, dry throat, thirst, internal heat, diabetes, yin deficiency, common cold, dizziness, and spasm and pain of tendons and vessels.

Lotus leaf, bitter and astringent in flavor, is neutral and enters liver, spleen, stomach and heart meridians. Has effects of clearing summer-heat, promoting diuresis, raising hair, clearing yang, cooling blood, and stopping bleeding. The lotus leaves can clear away summer heat, rise spleen yang, stabilize blood pressure and prevent and treat diseases such as hypertension, hyperlipidemia and the like; nuciferine has effects of clearing heart fire, suppressing liver fire, purging spleen fire, lowering lung fire, clearing heat, tranquilizing mind, regulating endocrine, and improving microcirculation. The traditional medicine considers that the lotus leaves have the activities of clearing summer heat, promoting diuresis, growing hair, clearing yang, clearing away heart-fire, removing heat, stopping bleeding and promoting diuresis.

The liquorice is sweet in taste and neutral in nature, enters heart, lung, spleen and stomach channels, and has the following main functions: invigorating spleen and replenishing qi, clearing away heat and toxic material, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the drugs. Can be used for treating weakness of spleen and stomach, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limb spasm, pain, carbuncle, swelling, sore, and drug toxicity and strong nature.

Preferably, the maca composition for improving yang deficiency and body cold of women is prepared from the following raw materials in percentage by weight: 40-50% of maca, 7-12% of ginseng, 4-8% of cinnamon, 3-7% of wolfberry, 4-7% of Chinese yam, 4-9% of sweet osmanthus, 1-4% of lily, 2-5% of polygonatum odoratum, 1-4% of lotus leaf, 2-6% of liquorice and the balance of auxiliary materials.

More preferably, the maca composition for improving yang deficiency and body cold of women is prepared from the following raw materials in percentage by weight: 45% of maca, 9.5% of ginseng, 6.5% of cinnamon, 5.0% of medlar, 5.5% of Chinese yam, 6.5% of sweet osmanthus, 2.5% of lily, 3.5% of polygonatum odoratum, 2.5% of lotus leaf, 3.5% of liquorice and the balance of auxiliary materials.

Preferably, the maca, the ginseng, the cinnamon, the medlar, the yam, the sweet osmanthus, the lily, the polygonatum, the lotus leaf and the liquorice are screened and directly crushed into fine powder with the particle size of less than 100 meshes.

The maca composition for improving the yang deficiency and the body cold of the female is prepared from solid preparation auxiliary materials which are mixed to prepare a clinically acceptable dosage form. The auxiliary materials can be selected from conventional solid preparation auxiliary materials.

Preferably, the dosage form is pills, tablets, capsules, granules, sustained release agents, controlled release agents, quick release agents, traditional Chinese medicine formula granules, soft extracts, oral liquid preparations or freeze-dried powder injections and the like.

The taking method comprises the following steps: the oral liquid is taken orally, the daily intake is less than 5g, and the oral liquid is recommended to be taken with honey water 30-60 min before meals in the daytime.

Some people have slight internal heat, and can relieve the symptoms by eating more green vegetables and drinking more water in a dinner, and if the symptoms do not disappear, the dosage can be reduced or the dosage can be taken at intervals.

Compared with the prior art, the invention has the beneficial effects that: the raw materials of the maca composition are all pure natural medicines, the prescription medication principle of the traditional Chinese medicine is followed, and all the components of the maca composition are compounded in a synergistic mode, so that the maca composition takes the effects of tonifying kidney and spleen, tonifying qi and yang, tonifying spleen and essence, nourishing liver and blood, and soothing liver and regulating qi as treatment rules, and has the effects of preventing and improving yang deficiency and body cold of women, tonifying essence and qi, activating blood and enriching blood, soothing channels and relieving pain, tonifying kidney and spleen, moistening lung and nourishing yin, and delaying senescence.

Detailed Description

The present invention is further described with reference to the following specific embodiments, which are intended to be illustrative only and not limiting, and although the invention has been described in detail with reference to the preferred embodiments, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted for elements thereof without departing from the spirit and scope of the invention as defined in the appended claims.

In the specific embodiment, the maca, the ginseng, the cinnamon, the medlar, the yam, the sweet osmanthus, the lily, the polygonatum, the lotus leaf and the liquorice are screened from raw materials and directly crushed into fine powder with the particle size of less than 100 meshes; adding conventional solid preparation adjuvants, and making into pill, tablet, capsule, granule, sustained release preparation, controlled release preparation, quick release preparation, Chinese medicinal granule, soft extract, oral liquid preparation or lyophilized powder for injection, etc.

Example 1

The maca composition for improving yang deficiency and body cold of women is prepared from the following raw materials in percentage by weight: 40% of maca, 12% of ginseng, 8% of cinnamon, 7% of medlar, 7% of Chinese yam, 9% of sweet osmanthus, 4% of lily, 5% of polygonatum odoratum, 4% of lotus leaf, 6% of liquorice and the balance of auxiliary materials; the auxiliary materials are conventional pill auxiliary materials.

The components are mixed to prepare the clinically acceptable pills.

Example 2

The maca composition for improving yang deficiency and body cold of women is prepared from the following raw materials in percentage by weight: 45% of maca, 9.5% of ginseng, 6.5% of cinnamon, 5.0% of medlar, 5.5% of Chinese yam, 6.5% of sweet osmanthus, 2.5% of lily, 3.5% of polygonatum odoratum, 2.5% of lotus leaf, 3.5% of liquorice and the balance of auxiliary materials; the auxiliary material is a conventional tablet auxiliary material.

The components are mixed to prepare the clinically acceptable tablets.

Example 3

The maca composition for improving yang deficiency and body cold of women is prepared from the following raw materials in percentage by weight: 50% of maca, 7% of ginseng, 4% of cinnamon, 3% of medlar, 4% of Chinese yam, 4% of sweet osmanthus, 1% of lily, 2% of polygonatum odoratum, 1% of lotus leaf, 2% of liquorice and the balance of auxiliary materials; the auxiliary materials are conventional granular auxiliary materials.

The components are mixed to prepare the clinically acceptable granular preparation.

Example 4

The maca composition for improving yang deficiency and body cold of women is prepared from the following raw materials in percentage by weight: 55% of maca, 5% of ginseng, 3% of cinnamon, 1% of medlar, 2% of Chinese yam, 10% of sweet osmanthus, 0.5% of lily, 7% of polygonatum odoratum, 0.3% of lotus leaf, 1% of liquorice and the balance of auxiliary materials; the auxiliary materials are conventional capsule auxiliary materials.

The components are mixed to prepare a clinically acceptable capsule preparation.

Example 5

The maca composition for improving yang deficiency and body cold of women is prepared from the following raw materials in percentage by weight: 35% of maca, 15% of ginseng, 10% of cinnamon, 10% of medlar, 10% of Chinese yam, 3% of sweet osmanthus, 5% of lily, 1% of polygonatum odoratum, 5% of lotus leaf, 6% of liquorice and the balance of auxiliary materials; the auxiliary material is a conventional freeze-dried powder injection auxiliary material.

The components are mixed to prepare the freeze-dried powder injection which is acceptable clinically.

Comparative example 1

The maca composition for improving yang deficiency and body cold of women is prepared from the following raw materials in percentage by weight: 45% of maca, 3% of ginseng, 1% of cinnamon, 5% of medlar, 12% of Chinese yam, 1% of sweet osmanthus, 2.5% of lily, 3.5% of polygonatum odoratum, 8% of lotus leaf, 9% of liquorice and the balance of auxiliary materials; the auxiliary material is a conventional tablet auxiliary material.

The components are mixed to prepare the clinically acceptable tablets.

Application example 1 evaluation of Effect of the present invention

600 female patients diagnosed as yang-deficiency and cold-constitution by a professional doctor are clinically selected, the age is 20-55 years, and the female patients are randomly divided into 6 groups, and 100 patients are selected. The diagnostic criteria include: 1) dizziness, asthenia, aversion to cold, cold hands and feet, dim complexion, amnesia, insomnia, short breath, slow speaking, reaction, absence of spirit, lack of luster of hair and skin, pachylosis, lusterless lips, pale tongue, weak pulse; 2) vertigo, tinnitus, soreness and weakness of waist and knees, dry mouth, feverish palms and soles, or tidal fever, sweating, pale red tongue with little coating, wiry, thready or thready and unsmooth pulse; 3) dysmenorrhea, irregular menstruation, asthenia, cold womb, swelling of chest, hypochondrium and breast, distending pain of lower abdomen, vexation, irritability and mental depression; 4) chest distress, lassitude, poor appetite, nausea, excessive and white leucorrhea, white and greasy tongue coating, wiry and slippery pulse, etc.

The treatment method comprises the following steps: 6 groups of patients take the composition preparations of the invention in examples 1-5 and comparative example 1 orally respectively, and take the composition preparation with honey water 30-60 min before meals for 2 times a day with the intake of less than 5g, and take the composition for 3 courses of treatment, and 10 days is a course of treatment.

The treatment effect judgment standard is that ① heals, the general symptoms completely disappear, and the patients do not relapse after lasting more than two months, ② improves the treatment, the general symptoms are obviously reduced, and the symptoms are continuously reduced to more than two months, ③ is ineffective, and the patients have no obvious reduction of the general symptoms.

The treatment results are as follows: as shown in table 1, the maca composition formula of embodiments 1 to 5 of the invention has a significant effect on improving yang deficiency and body cold of women, the effective rate of treatment is more than 97%, and particularly the effective rate of the formula of embodiments 1 to 3 is 100%; the composition of comparative example 1 has a certain curative effect on the deficiency of qi and blood in women, but the effective rate is obviously lower than that of the embodiment of the invention. The maca composition can obviously improve the constitution of the yang deficiency and the body cold of women through the synergistic compounding of the components.

Table 1 effect of different maca composition formulations on improving yang deficiency and body cold in women

Claims (3)

1. The maca composition for improving yang deficiency and body cold of women is characterized by comprising the following raw materials in percentage by weight: 45% of maca, 9.5% of ginseng, 6.5% of cinnamon, 5% of medlar, 5.5% of Chinese yam, 6.5% of sweet osmanthus, 2.5% of lily, 3.5% of polygonatum odoratum, 2.5% of lotus leaf, 3.5% of liquorice and the balance of auxiliary materials.

2. The maca composition for improving yang deficiency and body cold of women according to claim 1, wherein the auxiliary materials are solid preparation auxiliary materials, and the raw materials are mixed to prepare a clinically acceptable dosage form.

3. The maca composition for improving yang deficiency and body cold in women according to claim 2, wherein the dosage form is pills, tablets, capsules, granules or sustained release preparations.