CN109468224A - A kind of cell crushing instrument - Google Patents
A kind of cell crushing instrument Download PDFInfo
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- CN109468224A CN109468224A CN201811552387.6A CN201811552387A CN109468224A CN 109468224 A CN109468224 A CN 109468224A CN 201811552387 A CN201811552387 A CN 201811552387A CN 109468224 A CN109468224 A CN 109468224A
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- cell
- fixing seat
- sliding rail
- cell solution
- crushing
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- 230000007246 mechanism Effects 0.000 claims abstract description 47
- 239000004065 semiconductor Substances 0.000 claims description 10
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 8
- 239000007787 solid Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 75
- 238000000034 method Methods 0.000 description 8
- 230000000903 blocking effect Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 2
- FGRBYDKOBBBPOI-UHFFFAOYSA-N 10,10-dioxo-2-[4-(N-phenylanilino)phenyl]thioxanthen-9-one Chemical compound O=C1c2ccccc2S(=O)(=O)c2ccc(cc12)-c1ccc(cc1)N(c1ccccc1)c1ccccc1 FGRBYDKOBBBPOI-UHFFFAOYSA-N 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000006037 cell lysis Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Sustainable Development (AREA)
- Analytical Chemistry (AREA)
- Mechanical Engineering (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The present invention discloses a kind of cell crushing instrument, it is related to cell breaking plant field, including casing and power mechanism, the side of casing is provided with chamber door, casing internal is provided with sliding rail, fixing seat and crushing mechanism, sliding rail is set on casing internal bottom surface, and one end of sliding rail is close to chamber door, fixing seat is slidably installed on sliding rail, fixing seat is for placing the cell solution container for filling cell solution, power mechanism is for driving fixing seat to slide along sliding rail, crushing mechanism is set on casing internal top surface, and crushing mechanism is for being crushed the cell in cell solution container, when the cell crushing instrument uses, the position of cell solution container can be easily adjusted using power mechanism, and power mechanism can drive fixing seat to be moved to chamber door position, cell solution container taking and placing is convenient.
Description
Technical field
The present invention relates to cell breaking plant fields, more particularly to a kind of cell crushing instrument.
Background technique
Cell breaking technology, which refers to, destroys cell membrane and cell wall using external force, make cellular content include purpose product at
Divide the technology released.General clasmatosis is realized by special instrument.Using special instrument to cell
Be crushed, clasmatosis is quick, and crushing efficiency is high, but existing cell crushing instrument in use, cell solution container position
It adjustment and picks and places, is required to manpower and protrudes into inside device operated, be inconvenient.
Therefore it provides a kind of cell solution container position adjustment and pick and place convenient cell breaking plant be at present urgently
Problem to be solved.
Summary of the invention
The object of the present invention is to provide a kind of cell crushing instruments to make cell to solve the above-mentioned problems of the prior art
Solution container picks and places convenient.
To achieve the above object, the present invention provides following schemes:
The present invention provides a kind of cell crushing instrument, including casing and power mechanism, and the side of the casing is provided with chamber door,
The casing internal is provided with sliding rail, fixing seat and crushing mechanism, and the sliding rail is set on the casing internal bottom surface, and institute
One end of sliding rail is stated close to the chamber door, the fixing seat is slidably installed on the sliding rail, and the fixing seat is for putting
The cell solution container for filling cell solution is set, the power mechanism is for driving the fixing seat to slide along the sliding rail, institute
It states crushing mechanism to be set on the casing internal top surface, and the crushing mechanism is used for thin in the cell solution container
Born of the same parents are crushed.
It preferably, further include the battery, operation panel and controller being sequentially connected electrically, the crushing mechanism and described dynamic
Force mechanisms are electrically connected with the controller.
Preferably, the crushing mechanism includes sequentially connected Electrohydraulic push rod, link block, ultrasonic transducer and ultrasonic wave
Broken stick, the Electrohydraulic push rod are connect with the casing internal top surface, and it is molten that the ultrasonic disruption stick can extend into the cell
Liquid container is simultaneously crushed the cell in the cell solution container, the Electrohydraulic push rod and the ultrasonic transducer
It is electrically connected with the controller.
Preferably, cover board is arranged on the lateral wall of the ultrasonic disruption stick, when carrying out clasmatosis, the cover board energy
Enough block the opening of the cell solution container.
It preferably, further include symmetrically arranged two clamp systems, the sliding rail is line slide rail, two clamping machines
Structure is located at the two sides of the line slide rail and is fixed on the casing internal side, and two clamp systems can be to described
Cell solution container is fixed.
Preferably, the clamp system includes telescopic device and fixture block, and described telescopic device one end is fixed to the casing
In inner side, the other end of the telescopic device is fixedly connected with the fixture block, is all provided on the opposite face of two fixture blocks
It is equipped with half through slot, and two half through slots can be spliced into a whole through slot, the cell solution container can be clamped in
In the entirety through slot, it is provided with semiconductor chilling plate on the inner wall of each half through slot, is provided on the crushing mechanism
For detecting the temperature sensor of the temperature of the cell solution, the temperature sensor is electrically connected with the controller, each institute
The outer surface for stating semiconductor chilling plate is provided with non-slip mat.
Preferably, first pressure sensor, first pressure are provided on the opposite face of one of them clamp system
Force snesor is used to measure the pressure between two clamp systems, and the first pressure sensor is electrically connected with the controller
It connects.
Preferably, the power mechanism includes motor and screw rod, and the output end of the motor is connect with the screw rod, described
Screw rod is threadedly coupled with the fixing seat, and the sliding rail is provided with limited block far from one end of the chamber door, and the fixing seat is leaned on
The side of the nearly limited block is provided with second pressure sensor, the second pressure sensor for measure the fixing seat with
Pressure between the limited block, the motor and the second pressure sensor are electrically connected with the controller.
Preferably, the casing bottom end is provided with pedestal, and the pedestal bottom end is circumferentially evenly arranged with more along the pedestal
A resilient cushion.
It preferably, further include mentioning handle and pull ring, the handle that mentions is rotatably installed on the casing, the pull ring installation
In the outer surface of the chamber door.
The present invention achieves following technical effect compared with the existing technology:
Cell crushing instrument disclosed by the invention, casing internal is provided with sliding rail, and one end of sliding rail is close to chamber door, fixing seat
It is slidably installed on sliding rail, fixing seat is for placing the cell solution container for filling cell solution, and power mechanism is for driving
Dynamic fixing seat is slided along sliding rail, and the cell crushing instrument is in use, can easily adjust cell solution container using power mechanism
Position, and power mechanism can drive fixing seat to be moved to chamber door position, and cell solution container taking and placing is convenient.
Detailed description of the invention
It in order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, below will be to institute in embodiment
Attached drawing to be used is needed to be briefly described, it should be apparent that, the accompanying drawings in the following description is only some implementations of the invention
Example, for those of ordinary skill in the art, without any creative labor, can also be according to these attached drawings
Obtain other attached drawings.
Fig. 1 is the structural schematic diagram of ultrasonic cell disruption instrument provided by the invention；
Fig. 2 is the main sectional view of ultrasonic cell disruption instrument provided by the invention；
Fig. 3 is the cross-sectional view of bowing of casing in ultrasonic cell disruption instrument provided by the invention；
Fig. 4 is the top view of fixture block in ultrasonic cell disruption instrument provided by the invention；
Fig. 5 is the right view of fixture block in ultrasonic cell disruption instrument provided by the invention；
Fig. 6 is the circuit block diagram of ultrasonic cell disruption instrument provided by the invention.
In Fig. 1-Fig. 6:
1, handle is mentioned；2, casing；3, pull ring；4, chamber door；5, pedestal；6, cushion blocking；7, battery；8, operation panel；9, it controls
Device processed；10, conducting wire；11, shaft；12, Electrohydraulic push rod；13, ultrasonic transducer；14, ultrasonic disruption stick；15, fixture block；16,
Electric telescopic rod；17, fixing seat；18, sliding rail；19, screw hole；20, screw rod；21, sliding slot；22, cell solution container；23, transparent
Observation window；24, temperature sensor；25, cover board；26, link block；27, non-slip mat；28, half through slot；29, limited block；30, motor；
31, second pressure sensor；32, first pressure sensor；33, semiconductor chilling plate.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
The object of the present invention is to provide a kind of cell crushing instruments, of the existing technology to solve the problems, such as, make cell solution
It is convenient that the position of container adjusts and picks and places.
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, with reference to the accompanying drawing and specific real
Applying mode, the present invention is described in further detail.
Embodiment one
The present embodiment provides a kind of cell crushing instruments, as shown in Figure 1-Figure 3, including casing 2 and power mechanism, casing 2
Side is provided with chamber door 4, specifically, chamber door 4 is connected by hinge with casing 2, casing 2 is internally provided with sliding rail 18, fixing seat
17 and crushing mechanism, sliding rail 18 be set in 2 inner bottom surface of casing, specifically, sliding rail 18 and 2 inner bottom surface of casing pass through screw
Connection, and one end of sliding rail 18, close to chamber door 4, fixing seat 17 is slidably installed on sliding rail 18, specifically, fixing seat 17
Bottom end is provided with the sliding slot 21 matched with sliding rail 18, and fixing seat 17 is for placing the cell solution container for filling cell solution
22, for driving fixing seat 17 to slide along sliding rail 18, crushing mechanism is set in 2 inside top surface of casing power mechanism, and broken
Mechanism is for being crushed the cell in cell solution container 22, and the cell crushing instrument is in use, can using power mechanism
The position of convenient adjustment cell solution container 22, and power mechanism can drive fixing seat 17 to be moved to 4 position of chamber door, cell
Solution container 22 picks and places convenient.
In another specific embodiment of the present invention, as shown in figures 1 to 6, cell crushing instrument further includes being sequentially connected electrically
Battery 7, operation panel 8 and controller 9, crushing mechanism and power mechanism are electrically connected with controller 9, battery 7 and control
Device 9 is bolted with 2 outer wall of casing, and operation panel 8 is connected in the outer surface of controller 9, so set, passing through control
Device 9 can be automatically controled crushing mechanism and power mechanism work, and cell crushing instrument is more convenient to use.
In another specific embodiment of the present invention, as shown in Figure 2 and Figure 6, crushing mechanism includes sequentially connected electro-hydraulic pushes away
Bar 12, link block 26, ultrasonic transducer 13 and ultrasonic disruption stick 14, Electrohydraulic push rod 12 are connect with 2 inside top surface of casing, are surpassed
Sonication stick 14 can extend into cell solution container 22 and be crushed to the cell in cell solution container 22, Electrohydraulic push rod
12 and ultrasonic transducer 13 be electrically connected with controller 9, specifically, controller 9 passes through conducting wire 10 and ultrasonic transducer 13
Connection, using ultrasonic disruption mode, clasmatosis effect is good, and passes through setting 12 crushing mechanism height adjustment side of Electrohydraulic push rod
Just, device is more convenient to use.
In another specific embodiment of the present invention, as shown in Fig. 2, being arranged with cover board on the lateral wall of ultrasonic disruption stick 14
25, when carrying out clasmatosis, cover board 25 can block the opening of cell solution container 22, can be in cell by setting cover board 25
It effectively prevent cell solution to splash because of vibration in shattering process, avoids the waste of cell solution.
In another specific embodiment of the present invention, as shown in Figures 2 and 3, which further includes symmetrically arranged
Two clamp systems, sliding rail 18 are line slide rail, and two clamp systems are located at the two sides of line slide rail and are fixed on inside casing 2
On side, cell solution container 22 can be fixed in two clamp systems, and fluted, cell solution is arranged in fixing seat 17
The lower end of container 22 is installed in groove, so set, 22 position of cell solution container is fixed during clasmatosis, cell is broken
Broken more convenient, clasmatosis is more efficient.
In another specific embodiment of the present invention, as shown in Fig. 2-Fig. 6, clamp system includes telescopic device and fixture block 15,
Specifically, telescopic device is electric telescopic rod 16, telescopic device one end is welded and fixed in 2 inner side of casing, telescopic device
The other end be fixedly connected with fixture block 15, half through slot 28, and two and half through slots 28 are provided on the opposite face of two fixture blocks 15
It can be spliced into a whole through slot, cell solution container 22 can be clamped in whole through slot, thin by half through slot 28 of setting
Cell lysis liquid container 22 is more firm, and semiconductor chilling plate 33 is provided on the inner wall of fifty-fifty through slot 28, is arranged on crushing mechanism
There is the temperature sensor 24 of the temperature for detecting cell solution, temperature sensor 24 is electrically connected with controller 9,9 energy of controller
Enough information control semiconductor chilling plates 33 acquired according to temperature sensor 24 work, and plant automation degree is higher, using more
Add conveniently, and semiconductor chilling plate 33 is bonded cell solution container 22 in shattering process, so that cell solution is in shattering process
It can quickly cool down, avoid cell in shattering process and caused broken cell solution ingredient inactivation because cooling down slowly
It happens, improves the quality of clasmatosis, the outer surface of each semiconductor chilling plate 33 is provided with non-slip mat 27, by setting
Non-slip mat 27 is set, cell solution container 22 can be effectively prevent to loosen.
In another specific embodiment of the present invention, as shown in Figure 4-Figure 6, it is arranged on the opposite face of one of clamp system
There is first pressure sensor 32, specifically, being provided with first pressure sensor 32 on one of fixture block 15, clamp system is in
First pressure sensor 32 is in contact with another fixture block 15 when clamped condition, and first pressure sensor 32 is for measuring two folders
Pressure between tight mechanism, first pressure sensor 32 is electrically connected with controller 9, so set, controller 9 can be according to first
The information control clamp system work that pressure sensor 32 acquires, plant automation degree is higher, and device is more convenient to use, and
By the way that first pressure sensor 32 is arranged, it can effectively avoid between two two clamping structures that pressure is excessive, cause cell molten
The case where liquid container 22 damages.
In another specific embodiment of the present invention, as shown in Fig. 2, Fig. 3 and Fig. 6, power mechanism includes motor 30 and screw rod
20, the output end of motor 30 is connect with screw rod 20, and screw rod 20 is threadedly coupled with fixing seat 17, specifically, being arranged in fixing seat 17
There is screw hole 19, screw rod 20 is threadedly coupled with screw hole 19, and sliding rail 18 is welded with limited block 29, fixing seat 17 far from one end of chamber door 4
The side of limited block 29 is provided with second pressure sensor 31, second pressure sensor 31 is for measuring fixing seat 17 and limit
Pressure between the block 29 of position, motor 30 and second pressure sensor 31 are electrically connected with controller 9, so set, fixing seat 17
After reaching designated position, the information control power device that controller 9 can be acquired according to second pressure sensor 31 stops working,
Cell crushing instrument the degree of automation is higher, and device is more convenient to use.
In another specific embodiment of the present invention, as shown in Figure 1,2 bottom end of casing is provided with pedestal 5,5 bottom end of pedestal is the bottom of along
Seat 5 is circumferential to be evenly arranged with multiple cushion blockings 6, and specific cushion blocking 6 is that rubber damper is effectively mentioned by the way that cushion blocking 6 is arranged
The high stability of device.
In another specific embodiment of the present invention, as shown in Figure 1, further including mentioning handle 1 and pull ring 3, mentions handle 1 and rotationally pacify
Loaded on casing 2, pull ring 3 is installed on the outer surface of chamber door 4, and the both ends for specifically mentioning handle 1 respectively pass through a shaft 11 rotationally
It is installed on the side wall of casing 2, pull ring 3 is bonded and fixed to the outer surface of chamber door 4, mentions handle 1 and pull ring 3 by setting, device makes
With more convenient.
In another specific embodiment of the present invention, as shown in Figure 1, transparent windows 23 are provided on chamber door 4, by transparent
Observation window 23 can intuitively recognize the working condition inside device.
In specific work process, device is moved to clasmatosis position by mentioning handle 1 first by when use, passes through pull ring
3 open chamber door 4, and control the separation of two clamp systems, subsequent start-up motor 30 by controller 9, and motor 30 drives screw rod 20
Rotation, and then fixing seat 17 is moved to 4 position of chamber door, after seat 17 to be fixed is moved to 4 position of chamber door, it is molten can will to fill cell
The cell solution container 22 of liquid is placed in fixing seat 17, and inverts motor 30 by controller 9, so that fixing seat 17 is in spiral shell
It is mobile to the direction far from chamber door 4 under line transmission effect, so that second pressure sensor 31 is worked at the same time, when second pressure passes
, can be by force information back to controller 9 when sensor 31 touches limited block 29, and clamp system, the are made by controller 9
One pressure sensor 32 and Electrohydraulic push rod 12 work, and for clamp system again after task, two clamp systems are close to each other, when the first pressure
When force snesor 32 senses the touching of two clamp systems, two clamp systems stop working, and Electrohydraulic push rod 12 can drive super after working
Acoustic wave transducer 13 and ultrasonic disruption stick 14 move down, and observe cover board 25 and cell solution container when passing through transparent windows 23
When 22 contact, Electrohydraulic push rod 12 can be made to stop working, and 24 work of ultrasonic transducer 13 and temperature sensor is made by controller 9
Make, ultrasonic transducer 13 can be emitted in the cell solution into cell solution container 22 after working by ultrasonic disruption stick 14
Ultrasonic wave, and then to carry out cell fragmentation procedure, temperature sensor 24 can detect the temperature of cell solution the moment after working, when
When the temperature departure setting value of cell solution, semiconductor chilling plate 33 can be made to work by controller 9, device integrated automation journey
Degree is high, easy to use, and crushing effect is good.
It should be noted that the opposite face of clamp system refers to two symmetrically arranged clamp systems, it is one of to clamp
Face of the mechanism relative to another clamp system.
Specific examples are applied in the present invention, and principle and implementation of the present invention are described, above embodiments
Illustrate to be merely used to help understand method and its core concept of the invention；At the same time, for those skilled in the art, according to
According to thought of the invention, there will be changes in the specific implementation manner and application range.In conclusion the content of the present specification
It should not be construed as limiting the invention.
Claims (10)
1. a kind of cell crushing instrument, it is characterised in that: including casing and power mechanism, the side of the casing is provided with chamber door,
The casing internal is provided with sliding rail, fixing seat and crushing mechanism, and the sliding rail is set on the casing internal bottom surface, and institute
One end of sliding rail is stated close to the chamber door, the fixing seat is slidably installed on the sliding rail, and the fixing seat is for putting
The cell solution container for filling cell solution is set, the power mechanism is for driving the fixing seat to slide along the sliding rail, institute
It states crushing mechanism to be set on the casing internal top surface, and the crushing mechanism is used for thin in the cell solution container
Born of the same parents are crushed.
2. cell crushing instrument according to claim 1, it is characterised in that: further include the battery being sequentially connected electrically, operation
Panel and controller, the crushing mechanism and the power mechanism are electrically connected with the controller.
3. cell crushing instrument according to claim 2, it is characterised in that: the crushing mechanism includes sequentially connected electro-hydraulic
Push rod, link block, ultrasonic transducer and ultrasonic disruption stick, the Electrohydraulic push rod are connect with the casing internal top surface, institute
Stating ultrasonic disruption stick can extend into the cell solution container and carries out brokenly to the cell in the cell solution container
Broken, the Electrohydraulic push rod and the ultrasonic transducer are electrically connected with the controller.
4. cell crushing instrument according to claim 3, it is characterised in that: be arranged on the lateral wall of the ultrasonic disruption stick
There is cover board, when carrying out clasmatosis, the cover board can block the opening of the cell solution container.
5. cell crushing instrument according to claim 2, it is characterised in that: it further include symmetrically arranged two clamp systems,
The sliding rail is line slide rail, and two clamp systems are located at the two sides of the line slide rail and are fixed on the casing internal
On side, the cell solution container can be fixed in two clamp systems.
6. cell crushing instrument according to claim 5, it is characterised in that: the clamp system includes telescopic device and folder
Block, described telescopic device one end are fixed on the casing internal side, and the other end of the telescopic device and the fixture block are solid
Fixed connection, is provided with half through slot on the opposite face of two fixture blocks, and two half through slots can be spliced into one it is whole
Body through slot, the cell solution container can be clamped in the whole through slot, be provided on the inner wall of each half through slot
Semiconductor chilling plate is provided with the temperature sensor of the temperature for detecting the cell solution on the crushing mechanism, described
Temperature sensor is electrically connected with the controller, and the outer surface of each semiconductor chilling plate is provided with non-slip mat.
7. cell crushing instrument according to claim 6, it is characterised in that: on the opposite face of one of them clamp system
It is provided with first pressure sensor, the first pressure sensor is used to measure the pressure between two clamp systems, institute
First pressure sensor is stated to be electrically connected with the controller.
8. cell crushing instrument according to claim 2, it is characterised in that: the power mechanism includes motor and screw rod, institute
The output end for stating motor is connect with the screw rod, and the screw rod is threadedly coupled with the fixing seat, and the sliding rail is far from the case
One end of door is provided with limited block, and the fixing seat is provided with second pressure sensor close to the side of the limited block, described
Second pressure sensor is used to measure the pressure between the fixing seat and the limited block, the motor and the second pressure
Sensor is electrically connected with the controller.
9. cell crushing instrument according to claim 1, it is characterised in that: the casing bottom end is provided with pedestal, the bottom
Seat bottom end is circumferentially evenly arranged with multiple resilient cushions along the pedestal.
10. cell crushing instrument according to claim 1, it is characterised in that: further include mentioning handle and pull ring, the handle that mentions can turn
It is installed on the casing dynamicly, the pull ring is installed on the outer surface of the chamber door.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811552387.6A CN109468224B (en) | 2018-12-18 | 2018-12-18 | Cell disruption instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811552387.6A CN109468224B (en) | 2018-12-18 | 2018-12-18 | Cell disruption instrument |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109468224A true CN109468224A (en) | 2019-03-15 |
| CN109468224B CN109468224B (en) | 2022-02-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811552387.6A Expired - Fee Related CN109468224B (en) | 2018-12-18 | 2018-12-18 | Cell disruption instrument |
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| Country | Link |
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| CN (1) | CN109468224B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114308293A (en) * | 2021-12-17 | 2022-04-12 | 郭礼胜 | Medical treatment biological tissue triturating device |
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| CN114308293A (en) * | 2021-12-17 | 2022-04-12 | 郭礼胜 | Medical treatment biological tissue triturating device |
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| CN109468224B (en) | 2022-02-11 |
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