CN1094361C - 含有蜂胶和香精油的组合物 - Google Patents

含有蜂胶和香精油的组合物 Download PDF

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CN1094361C
CN1094361C CN98807944A CN98807944A CN1094361C CN 1094361 C CN1094361 C CN 1094361C CN 98807944 A CN98807944 A CN 98807944A CN 98807944 A CN98807944 A CN 98807944A CN 1094361 C CN1094361 C CN 1094361C
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安德烈·皮埃尔·莫里斯
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Abstract

本发明涉及一种含蜂胶和至少一种香精油的组合物和所述组合物的应用。

Description

含有蜂胶和香精油的组合物
本发明涉及含有蜂胶(propolis)和至少一种香精油的组合物，本发明还涉及该组合物的用途。
蜂胶是由蜜蜂合成的化学物质，它存在于蜂巢的内表面上，蜂胶的抗病毒活性是已知的。
可惜的是，蜂胶对某些病毒，例如耐抗病毒化学治疗的病毒没有足够的抗病毒活性。
因此，人们需要具有足够抗病毒活性并可以很低剂量使用的组合物。
因此，本发明的目的是一种组合物，其特征在于它含有蜂胶和至少一种香精油。
组合物表现出以非常低的剂量使用两种容易得到的天然来源的组分的优点，并同时其组合显示杰出的抗病毒活性。
除了抗病毒治疗之外，另一优点是组合物能够治疗起因于细菌和/或真菌的症状。本发明的组合物还有容易用于皮肤和/或粘膜或被活体咽下的优点。
本发明的另一目的是含有蜂胶和至少一种香精油的组合物作为抗病毒剂的用途。
本发明的第三个目的是含有蜂胶和至少一种香精油的组合物在制备用于治疗细菌疾病的药物中的用途。
该组合物能够治疗尤其与存在非包膜的含DNA病毒(腺病毒)包膜病毒，例如疱疹病毒或HSV1病毒有关的疾病，或与存在***状瘤病毒或非包膜的含有RNA病毒(2型脊髓灰质炎病毒)或包膜病毒有关的疾病。
本发明的第四个是含有蜂胶和至少一种香精油的组合物在制备用于治疗皮肤和/或粘膜上的真菌感染的药物中的用途。
该组合物尤其可用于治疗与存在葡萄球菌、β-溶血链球菌、肠杆菌(大肠杆菌)、绿脓菌(绿脓假单胞菌)有关的感染。
最后，本发明的最后一个目的是含有蜂胶和至少一种香精油的组合物在制备用于皮肤和/或粘膜细胞和组织再生的药物中的用途。
在适当地清洗和除去杂质后，蜂胶与香精油冷混合。
油选自化学纯化合物。这些化合物优选选自芳香化合物，例如苯甲酸、苯甲醛或肉桂酸的醇、选自类黄酮、萜烯，例如β-没药醇、α-乙酰氧基桦木醇、选自酯、醇、氧化物、醛、酮、内酯、酚、选自其它具有相似或类似物理一化学性能或这些不同化学分子的混合物。
本发明的组合物可含有天然香精油，其选自牛至(Origan)、牛至香芹酚(Origan  Carvacrol)、丁香(Girofle)、鼠尾草(Sauge)、百里香(Thym)、互生叶白千层属(Mélaleuca  alternifolia)、白千层萜品醇(Mélaceuca terpinéol)、柏树(Cyprès)、柠檬桉(Eucalyptus citronné)、dives桉(Eucalyptus dives)、radiata桉(Eucalyptus radiata)、蓝桉(Eucalypyus  globulus)、臭马鞭草(Verveine odorante)、迷迭香(Romarin  officinal)、胶冷杉(Sapin baumier)、香脂冷杉(sapin  Baumé)、Provence薄荷(Sarriette de Provence)、斯里兰卡肉桂(Cannelle de Ceylan)、中国肉桂(Cannelle de Chine)、熏衣草(Lavande)、马鞭草(Verveine)之油和它们的混合物。
香精油优选以相对组合物总重量的0.1％量存在。
蜂胶优选含有50-55％的树脂和香脂、30-40％蜡、5-10％香精油、5％花粉、5％有机和无机物。蜂胶优选为相对于组合物总重量计以10％(重量)存在。
本发明的组合物还含有至少一种选自维生素、微量元素、蔗糖、酶、醇、凡士林的添加剂。
本发明的组合物可以是不同制剂形式，例如栓剂、软膏、酊剂、吸入剂、胶囊、片剂、洗剂、***栓形式。
本发明的组合物可以由用于皮肤和/或粘膜的化妆品和/或皮肤病学组合物组成。
本发明用如下实施例说明，而不是限制性的。
不同的浓度以重量百分数给出。实施例1：
蜂胶               10.0
白千层属           0.1
赋形剂         适量至100
该组合物是用于治疗***感染的***栓剂形式。
实施例2
蜂胶              10.0
牛至香芹酚        0.1
白千层萜品醇      0.1
香薄荷            0.1
丁香              0.1
鼠尾草            0.1
赋形剂       适量至100
该组合物是用于治疗细菌和真菌感染的洗剂形式。

Claims (14)

1.组合物，含有蜂胶和至少一种选自如下的香精油：牛至、丁香、马鞭草、臭马鞭草、胶冷杉、香脂冷杉、Provence薄荷、互生叶白千层属、白千层萜品醇之油和它们的混合物。
2.权利要求1的组合物，其特征在于它含有蜂胶和至少两种选自如下的油：牛至、Provence薄荷、互生叶白千层属、白千层萜品醇、丁香和它们的混合物。
3.权利要求2的组合物，其特征在于它另外还含有至少一种选自如下的油：鼠尾草、熏衣草和它们的混合物。
4.权利要求3的组合物，其特征在于它含有蜂胶和如下香精油：牛至、Provence薄荷、鼠尾草、丁香、熏衣草和白千层萜品醇。
5.权利要求1～4之任一项的组合物，其特征在于香精油按组合物总重量计，以0.1％(重量)存在。
6.权利要求1～4之任一项的组合物，其特征在于蜂胶含：
50～55％树脂和香脂，
30～40％蜡，
5～10％香精油，
5％花粉，
5％有机和无机物。
7.权利要求1、2、3或6之一项的组合物，其特征在于蜂胶按组合物总重量计，以10％(重量)存在。
8.上述权利要求之任一项的组合物，其特征在于它包括选自维生素、微量元素、酶、蔗糖、醇、凡士林的添加剂。
9.上述权利要求之任一项的组合物，其特征在于它呈栓剂、软膏、酊剂、吸入剂、胶囊、片剂、洗剂或***栓剂形式。
10.上述权利要求之任一项的组合物，其特征在于是一种用于皮肤和/或粘膜的化妆品和/或皮肤病学的组合物。
11.上述权利要求之任一项所确定的组合物在制备治疗病毒感染的药物中的应用。
12.上述权利要求之任一项所确定的组合物在制备治疗细菌感染的药物中的应用。
13.上述权利要求之任一项所确定的组合物在制备治疗皮肤和/或粘膜真菌感染的药物中的应用。
14.包括蜂胶和至少一种香精油的组合物在制备用于皮肤和/或粘膜的细胞和组织再生的药物中的应用。
CN98807944A 1997-08-11 1998-08-04 含有蜂胶和香精油的组合物 Expired - Fee Related CN1094361C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR97/10414 1997-08-11
FR9710414A FR2767061A1 (fr) 1997-08-11 1997-08-11 Produits naturels au service de la vie contenant du propolis et des huiles essentielles
FR9802027A FR2767062B1 (fr) 1997-08-11 1998-02-19 Composition comprenant de la propolis
FR98/02027 1998-02-19

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CN1265597A CN1265597A (zh) 2000-09-06
CN1094361C true CN1094361C (zh) 2002-11-20

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US (1) US6680074B1 (zh)
EP (1) EP1003537B1 (zh)
JP (1) JP2002529369A (zh)
CN (1) CN1094361C (zh)
AR (1) AR013411A1 (zh)
AT (1) ATE208626T1 (zh)
BR (1) BR9811152A (zh)
CA (1) CA2301068A1 (zh)
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ES (1) ES2168155T3 (zh)
FR (1) FR2767062B1 (zh)
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FR2837105B1 (fr) * 2002-03-13 2004-07-23 Jean Bringer Composition associant la propolis a une essence aromatique
US20050013882A1 (en) * 2003-04-16 2005-01-20 Jacques Owen Phyto fluid
DE20306600U1 (de) * 2003-04-29 2003-09-04 Karpfl Vera Hautpflegeprodukt bzw. Wundpflegemittel
GB2406053B (en) * 2003-09-10 2008-08-20 Micap Plc Antimicrobial composition
AT502628A1 (de) * 2005-11-09 2007-05-15 Imhof Martin Dr Verwendung von propolis zur herstellung eines medikaments
US8206761B2 (en) * 2009-12-16 2012-06-26 Kutumian Dzovig M Multipurpose cleaner and method of cleaning using therapeutic grade essential oils
WO2016014699A1 (en) 2014-07-22 2016-01-28 Ralco Nutrition, Inc. Antiviral compositions and methods
IT201600109403A1 (it) * 2016-10-28 2018-04-28 Bio Lo Ga Srl Composizione per applicazione topica con attività antimicotica
FR3073125B1 (fr) * 2017-11-08 2020-05-29 Eric Bottalico Composition pour la conservation des tissus
KR102408968B1 (ko) * 2020-09-03 2022-06-13 유창우 프로폴리스 및 티트리 추출물을 함유한 복합 항균 조성물

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WO1997002040A1 (en) * 1995-07-03 1997-01-23 Bevilacqua, Maria Terpene-based pharmaceutical product

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EP1003537B1 (fr) 2001-11-14
ATE208626T1 (de) 2001-11-15
DK1003537T3 (da) 2003-09-22
ES2168155T3 (es) 2002-06-01
JP2002529369A (ja) 2002-09-10
DE69802545D1 (de) 2001-12-20
WO1999007396A1 (fr) 1999-02-18
DE69802545T2 (de) 2002-06-27
AR013411A1 (es) 2000-12-27
BR9811152A (pt) 2000-07-25
US6680074B1 (en) 2004-01-20
PT1003537E (pt) 2002-04-29
CA2301068A1 (fr) 1999-02-18
FR2767062A1 (fr) 1999-02-12
FR2767062B1 (fr) 2000-03-17
CN1265597A (zh) 2000-09-06
HK1030154A1 (en) 2001-04-27

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