CN109419005A - It is a kind of replenish the calcium, the composition of bone glue of yak former peptide of hypoglycemic and preparation method thereof - Google Patents
It is a kind of replenish the calcium, the composition of bone glue of yak former peptide of hypoglycemic and preparation method thereof Download PDFInfo
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- CN109419005A CN109419005A CN201710767580.0A CN201710767580A CN109419005A CN 109419005 A CN109419005 A CN 109419005A CN 201710767580 A CN201710767580 A CN 201710767580A CN 109419005 A CN109419005 A CN 109419005A
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- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 40
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims abstract description 27
- 239000011575 calcium Substances 0.000 title claims abstract description 27
- 229910052791 calcium Inorganic materials 0.000 title claims abstract description 27
- 230000002218 hypoglycaemic effect Effects 0.000 title claims abstract description 15
- 239000002639 bone cement Substances 0.000 title claims abstract description 14
- 239000000203 mixture Substances 0.000 title claims abstract description 10
- 238000002360 preparation method Methods 0.000 title abstract description 6
- 239000000843 powder Substances 0.000 claims abstract description 19
- MVORZMQFXBLMHM-QWRGUYRKSA-N Gly-His-Lys Chemical compound NCCCC[C@@H](C(O)=O)NC(=O)[C@@H](NC(=O)CN)CC1=CN=CN1 MVORZMQFXBLMHM-QWRGUYRKSA-N 0.000 claims abstract description 15
- 108010038983 glycyl-histidyl-lysine Proteins 0.000 claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 11
- 238000007689 inspection Methods 0.000 claims abstract description 7
- 238000005303 weighing Methods 0.000 claims abstract description 7
- 238000003860 storage Methods 0.000 claims abstract description 4
- 238000012360 testing method Methods 0.000 claims description 15
- 241000255789 Bombyx mori Species 0.000 claims description 14
- 239000000463 material Substances 0.000 claims description 13
- 229910052751 metal Inorganic materials 0.000 claims description 3
- 239000002184 metal Substances 0.000 claims description 3
- 238000012009 microbiological test Methods 0.000 claims description 3
- 238000004806 packaging method and process Methods 0.000 claims description 3
- 238000012856 packing Methods 0.000 claims description 3
- 239000004575 stone Substances 0.000 claims description 3
- 210000000988 bone and bone Anatomy 0.000 abstract description 24
- 102000008186 Collagen Human genes 0.000 abstract description 14
- 108010035532 Collagen Proteins 0.000 abstract description 14
- 230000000694 effects Effects 0.000 abstract description 14
- 210000004369 blood Anatomy 0.000 abstract description 8
- 239000008280 blood Substances 0.000 abstract description 8
- 102000004196 processed proteins & peptides Human genes 0.000 abstract description 7
- 241000169546 Lycium ruthenicum Species 0.000 abstract description 6
- 239000005018 casein Substances 0.000 abstract description 6
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract description 6
- 235000021240 caseins Nutrition 0.000 abstract description 6
- 230000036039 immunity Effects 0.000 abstract description 6
- 108010001441 Phosphopeptides Proteins 0.000 abstract description 5
- 229920001202 Inulin Polymers 0.000 abstract description 4
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 abstract description 4
- 229940029339 inulin Drugs 0.000 abstract description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract description 2
- 239000008103 glucose Substances 0.000 abstract description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 abstract 1
- 239000010931 gold Substances 0.000 abstract 1
- 229910052737 gold Inorganic materials 0.000 abstract 1
- 239000000047 product Substances 0.000 description 12
- 241000700159 Rattus Species 0.000 description 11
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- 210000002966 serum Anatomy 0.000 description 6
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- 102000004190 Enzymes Human genes 0.000 description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- 150000002632 lipids Chemical class 0.000 description 4
- 241000382353 Pupa Species 0.000 description 3
- 229940088598 enzyme Drugs 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 229920002101 Chitin Polymers 0.000 description 2
- 229920001661 Chitosan Polymers 0.000 description 2
- 208000017667 Chronic Disease Diseases 0.000 description 2
- KQLDDLUWUFBQHP-UHFFFAOYSA-N Cordycepin Natural products C1=NC=2C(N)=NC=NC=2N1C1OCC(CO)C1O KQLDDLUWUFBQHP-UHFFFAOYSA-N 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 208000021017 Weight Gain Diseases 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
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- 238000007705 chemical test Methods 0.000 description 2
- RQFQJYYMBWVMQG-IXDPLRRUSA-N chitotriose Chemical compound O[C@@H]1[C@@H](N)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](N)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)[C@@H](CO)O1 RQFQJYYMBWVMQG-IXDPLRRUSA-N 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- OFEZSBMBBKLLBJ-BAJZRUMYSA-N cordycepin Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)C[C@H]1O OFEZSBMBBKLLBJ-BAJZRUMYSA-N 0.000 description 2
- OFEZSBMBBKLLBJ-UHFFFAOYSA-N cordycepine Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(CO)CC1O OFEZSBMBBKLLBJ-UHFFFAOYSA-N 0.000 description 2
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- 102000004169 proteins and genes Human genes 0.000 description 2
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- 230000004584 weight gain Effects 0.000 description 2
- 235000019786 weight gain Nutrition 0.000 description 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
- QCVGEOXPDFCNHA-UHFFFAOYSA-N 5,5-dimethyl-2,4-dioxo-1,3-oxazolidine-3-carboxamide Chemical compound CC1(C)OC(=O)N(C(N)=O)C1=O QCVGEOXPDFCNHA-UHFFFAOYSA-N 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- 244000189799 Asimina triloba Species 0.000 description 1
- 235000006264 Asimina triloba Nutrition 0.000 description 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical group [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 1
- 235000009467 Carica papaya Nutrition 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
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- 241000196324 Embryophyta Species 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 108090000526 Papain Proteins 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 108010009736 Protein Hydrolysates Proteins 0.000 description 1
- 238000010266 Sephadex chromatography Methods 0.000 description 1
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- 229930014669 anthocyanidin Natural products 0.000 description 1
- 150000001452 anthocyanidin derivatives Chemical class 0.000 description 1
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- 230000006870 function Effects 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000002366 mineral element Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229940055729 papain Drugs 0.000 description 1
- 235000019834 papain Nutrition 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 239000003531 protein hydrolysate Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
It is a kind of replenish the calcium, the composition of the bone glue of yak former peptide of hypoglycemic, which is characterized in that component and proportion are as follows: Yak Bone collagen protein peptide powder 70.00~75.00%；Tussah chrysalis Gly-His-Lys 8.00~10.00%；Casein phosphopeptide 5.00~8.00%；Inulin 3.00~5.00%；Lycium ruthenicum freeze-dried powder 1.00~2.00%.Its step of preparation process includes: that (1) raw material is checked and accepted；(2) mixing；(3) it packs；(4) gold inspection, weighing；(5) vanning storage.Advantage is: the scientific matching of each component, effectively enhances the bioavailability of each component, and manufactured complex peptides powder is to improving immunity, reduce blood glucose and replenish the calcium and have good curative effect.
Description
Technical field
The invention belongs to health foods, in particular to a kind of to utilize Yak Bone collagen protein peptide powder made of Yak Bone, toothed oak
Silkworm chrysalis peptide made of silkworm chrysalis be major ingredient, add other auxiliary materials preparation it is a kind of replenish the calcium, the composition of the bone glue of yak former peptide of hypoglycemic
Health food.Aim to solve the problem that the single bone peptide product of tradition in the deficiency for reducing blood glucose and aspect of replenishing the calcium.
Background technique
Yak Bone collagen protein peptide powder is the defibrination after high temperature and pressure boiling using Yak Bone as raw material, recycles pawpaw egg
White enzyme carries out enzymatic hydrolysis to bone collagen in pulp, will hydrolyze Bone gillg magma, spray-dried rear resulting bone peptide
Powder.Primary efficacy is small-molecular peptides, is easily absorbed, containing human body thus a variety of amino acid and minerals, particularly 8 kinds it is necessary
Amino acid.It improves the immunity of the human body simultaneously, accelerate cell repair, having good curative effect to chronic disease.Currently, there is one kind
The nutrition complex peptides powder of effect of replenishing the calcium is to carry out Yak Bone Gly-His-Lys and tussah chrysalis Gly-His-Lys and casein phosphopeptide, chitosan oligosaccharide
Reasonable compatibility forms.It is different from ox bone Gly-His-Lys common on the market and finds that this Gly-His-Lys inherits common ox by zoopery
The effect of bone peptide powder, while there is extremely strong effect of replenishing the calcium.The Gly-His-Lys product occurred on the market mostly be based on Yak Bone Gly-His-Lys,
Isin glue collagen peptide or some plant peptides is added.These products have certain effect, but replenish the calcium, in terms of hypoglycemic but
There are serious deficiencies, and there are no make product using Yak bone peptide and silkworm chrysalis peptide compatibility.
Summary of the invention
The present invention is using Gannon State bone as raw material, the defibrination after high temperature and pressure boiling, recycles papain to pulp
Middle bone collagen carries out enzymatic hydrolysis, will hydrolyze Bone gillg magma, and spray-dried rear resulting bone peptide powder is equipped with Jilin
Complex peptides powder is made in tussah chrysalis Gly-His-Lys, casein phosphopeptide and chitosan oligosaccharide, the inulin of the wild tussah production in Changbai Mountain.This Gly-His-Lys group
Closing object has raising immunity, supplement calcium, the good efficacy of assistant hypoglycemic.It can be suitble to functional food and health care product.
The technical scheme is that realize as follows, it is a kind of replenish the calcium, the composition of the bone glue of yak former peptide of hypoglycemic, match
Expect weight percent are as follows:
Wherein, Yak Bone collagen protein peptide powder is major ingredient, and collagen Gly-His-Lys are that collagen is obtained by albumen enzyme effect
The protein hydrolysate arrived has the advantages that molecular weight is small, human body easily absorbs, and the human absorptivity of collagen peptide is in 95-
Between 100, it is far longer than the absorptivity of collagen.It can regain one's strength of body rapidly, relieve fatigue.
Silkworm chrysalis peptide is that the Silkworm pupa protein after SCF-CO 2 silkworm chrysalis oil is that raw material carries out silkworm pupa protein polypeptide enzyme
Solution, and silkworm pupa protein polypeptide is isolated and purified by ion exchange resin desalination, G-50 sephadex chromatography, divided
Son amount has the Functional Polypeptides of anti-fatigue active lower than 3000Da.
Casein phosphopeptide (CPPs) is a kind of biologically active peptide extracted from the casein of milk, and having been demonstrated that has
Promote the mineral elements such as calcium, iron to absorb, prevent the physiological functions such as decayed tooth.
Inulin is pure natural water-soluble dietary fiber.With the secret rush digestion of defaecation, toxin-expelling and face nourishing, reducing blood lipid is hypoglycemic, subtracts
The multi-functionals such as fertilizer, liver function protecting.It is pure natural without any additive, applicable object-is suitable for people of all ages.It is especially suitable for constipation, mouth
Smelly, diabetes, hyperlipidemia is lower for the resistance, often stays up late, chronic disease, and using antibiotic, often drink equal crowds.
Chitosan by (Isosorbide-5-Nitrae)-linked2-amino-2-deoxy- β-D-glucose form it is a kind of it is nontoxic can biology drop
The cationic polysaccharide of solution.Chitosan has the excellent performance of high molecular polymer, such as biocompatibility, biological degradability, nothing
Toxicity, at low cost etc..With good function of reducing blood sugar.
The sweet in flavor and neutral in nature of lycium ruthenicum, being capable of nourishing liver and kidney, benefiting shrewd head and blood-nourishing, the immunity for enhancing people.In addition, black
Fructus lycii can liver protection, it is hypoglycemic, softening blood vessel, reduce blood in cholesterol, triglyceride levels, to fatty liver and diabetes
Patient has certain curative effect.Lycium ruthenicum can be with beauty, and the anthocyanidin being rich in lycium ruthenicum is natural sunlight overcover, can be with
Effectively prevent damage of the ultraviolet light to skin.And the procyanidine in lycium ruthenicum can fight the oxidation of outer bound pair cell well
Effect, can effectively clear the accumulation and precipitating of skin harmful substance free radical, and collagen egg is protected in delaying human body cell tissue aging
It is white, it makes skin fresh and alive flexible, keeps younger state, reduce wrinkle, delay.
The above raw material is proportionally mixed, produce it is a kind of replenish the calcium, the combination of the bone glue of yak former peptide of hypoglycemic
Object.It is edible for convenience, improve taste, need to add certain suitable additives, obtains the edible good result of different crowd.
The present invention it is a kind of replenish the calcium, the step of preparation process of the composition of the bone glue of yak former peptide of hypoglycemic includes:
(1), raw material examination carry out an acceptance inspection according to related raw material test stone to each auxiliary material of original, mainly including appearance,
Physical and chemical and Micro biological Tests, can after qualified.
(2), auxiliary material is put into small-sized V-type batch mixer progress mixing according to formula rate is existing by mixing.It is required that mixing time is
It 40-45 minutes, thoroughly mixes；Bone glue of yak former peptide powder, silkworm chrysalis Gly-His-Lys are put in proportion into large-scale V-type batch mixer, are first mixed
After twenty minutes, mixed auxiliary material is put into, is continued mixing 40-45 minutes, until mixing.
(3), packaging packs mixed material by upright packing machine.
(4), the good inner bag of Jin Jian, weighing and bagging fills qualified product after metal inspection and weighing equipment
It is fabricated to finished product after box, date printed, is put in storage.Be made in flaxen pulverulent solids pulvis, have replenish the calcium, reducing blood lipid,
Improve the new health care product of immunity.
The present invention has following advantages and effect compared with the existing technology.
(1), the Yak Bone collagen protein peptide powder that the present invention uses is combined with silkworm chrysalis Gly-His-Lys.Silkworm chrysalis peptide has containing a large amount of
Cordycepin, the content of cordycepin are 3-5 times of natural cs, to the postoperative antisecosis of cancer, chemotherapy adverse effect and gastrointestinal tract
Disease, chronic anaemia have good effect.Silkworm chrysalis peptide contains nearly 25% chitin, and clinical test shows chitin pair
Reducing blood lipid has good curative effect.
(2), embodiment 1
The feeding experiment of rat is done, with bone glue of yak former peptide powder 75%, tussah chrysalis Gly-His-Lys 10%, casein phosphopeptide 5%,
Inulin 8%, lycium ruthenicum freeze-dried powder 2% are test group；Using the calcium carbonate group of same calcium level as control group.After feeding experiment
It is analyzed using calcium content of bone of the atomic absorption spectrophotometer to rat；Rat bone is measured using Dual-energy X-rays absorptionmetry
Density increases situation；Rat blood serum biochemical indicator (alkaline phosphatase is measured using automatic clinical chemistry analyzer and blomelicalbloodgasandelectrolrteanalyzers
Enzyme, triglycerides, cholesterol and K+, Na+, Cl-, Ca2+).Result of study is as follows: 1, feeding experiment shows that two groups of rats are raw
Long development is normal.Rats in test groups be averaged Day feeding amount be 13.57g/ only；Two groups of rat body weight weight gains are respectively 150.60g/
Only, 115.46g/；Rats in test groups femur weight, Day feeding amount and weight gain are extremely significant to be higher than control group (P <
0.01).2, rats in test groups bone density is higher than control group by 23.48% respectively, and difference is extremely significant (P < 0.01).Rat femur calcium
Content is higher than control group by 8.56%, significant difference (P < 0.05), and effect of replenishing the calcium of test group is more apparent.3, in test group serum
AKP and TG content is compared with the control group without statistical difference (P > 0.05)；CHO content is 2.090mmol/L, test group
Substantially less than control group (P < 0.05), reduces 9.82% compared with control group.7, potassium, the sodium nothing between each group in test group serum
Statistical difference (P > 0.05), but serum calcium levels test group is 2.873mmol/L, substantially less than control group (P < 0.01, P
< 0.05), 4.71% is reduced respectively compared with control group；Serum chlorinity is 116.641mmol/L, and test group, which is substantially less than, to be compareed
Group (P < 0.05).8, test result shows that the rat bone calcium of edible osteotrophy powder, bone density dramatically increase, and will not be right
Serum AKP level, TG, CHO and electrolyte balance have an impact, and are a kind of natural calcium supplementing products.
Specific embodiment
The technical scheme is that it is a kind of replenish the calcium, the composition of the bone glue of yak former peptide of hypoglycemic, component and proportion
Are as follows:
It is a kind of replenish the calcium, the step of preparation process of the Yak Bone collagen composite peptide powder of hypoglycemic includes:
(1), raw material examination carry out an acceptance inspection according to related raw material test stone to each auxiliary material of original, mainly including appearance,
Physical and chemical and Micro biological Tests, can after qualified.
(2), auxiliary material is put into small-sized V-type batch mixer progress mixing according to formula rate is existing by mixing.It is required that mixing time is
It 40-45 minutes, thoroughly mixes；Bone glue of yak former peptide powder, silkworm chrysalis Gly-His-Lys are put in proportion into large-scale V-shaped batch mixer, are first mixed
After twenty minutes, mixed auxiliary material is put into, is continued mixing 40-45 minutes, until mixing.
(3), packaging packs mixed material by upright packing machine.
(4), the good inner bag of Jin Jian, weighing and bagging fills qualified product after metal inspection and weighing equipment
It is fabricated to finished product after box, date printed, is put in storage.Be made in flaxen pulverulent solids pulvis, have replenish the calcium, reducing blood lipid,
Improve the new health care product of immunity.
Claims (2)
1. it is a kind of replenish the calcium, the composition of the bone glue of yak former peptide of hypoglycemic, component and proportion are as follows:
。
2. as described in claim 1, it is a kind of replenish the calcium, the composition of the bone glue of yak former peptide of hypoglycemic, which is characterized in that it is prepared
Processing step includes:
(1), raw material examination carries out an acceptance inspection to each auxiliary material of original according to related raw material test stone, mainly includes appearance, physics and chemistry
And Micro biological Tests, it can after qualified.
(2), auxiliary material is put into small-sized V-type batch mixer progress mixing according to formula rate is existing by mixing.It is required that mixing time is 40-
It 45 minutes, thoroughly mixes；Bone glue of yak former peptide powder, silkworm chrysalis Gly-His-Lys are put in proportion into large-scale V-shaped batch mixer, first mix 20 points
Zhong Hou puts into mixed auxiliary material, continues mixing 40-45 minutes, until mixing.
(3), packaging packs mixed material by upright packing machine.
(4), the good inner bag of Jin Jian, weighing and bagging, after metal inspection and weighing equipment, by qualified product carry out mounted box,
It is fabricated to finished product after date printed, is put in storage.
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Application publication date: 20190305 |