CN109406498B - 一种免疫测定装置 - Google Patents
一种免疫测定装置 Download PDFInfo
- Publication number
- CN109406498B CN109406498B CN201710695530.6A CN201710695530A CN109406498B CN 109406498 B CN109406498 B CN 109406498B CN 201710695530 A CN201710695530 A CN 201710695530A CN 109406498 B CN109406498 B CN 109406498B
- Authority
- CN
- China
- Prior art keywords
- reading
- incubator
- pushing
- strip
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000003018 immunoassay Methods 0.000 title claims abstract description 46
- 239000011259 mixed solution Substances 0.000 claims abstract description 15
- 238000012545 processing Methods 0.000 claims abstract description 14
- 230000007246 mechanism Effects 0.000 claims description 109
- 239000003153 chemical reaction reagent Substances 0.000 claims description 39
- 238000011534 incubation Methods 0.000 claims description 26
- 238000004140 cleaning Methods 0.000 claims description 17
- 239000012895 dilution Substances 0.000 claims description 16
- 238000010790 dilution Methods 0.000 claims description 16
- 230000003321 amplification Effects 0.000 claims description 8
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 8
- 238000001816 cooling Methods 0.000 claims description 6
- 230000008105 immune reaction Effects 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 3
- 238000007865 diluting Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 11
- 238000001514 detection method Methods 0.000 abstract description 10
- 239000000523 sample Substances 0.000 description 72
- 238000000034 method Methods 0.000 description 26
- 239000000427 antigen Substances 0.000 description 19
- 102000036639 antigens Human genes 0.000 description 19
- 108091007433 antigens Proteins 0.000 description 19
- 230000006872 improvement Effects 0.000 description 14
- 230000008569 process Effects 0.000 description 14
- 239000000126 substance Substances 0.000 description 13
- 239000002245 particle Substances 0.000 description 11
- 238000010586 diagram Methods 0.000 description 10
- 239000003550 marker Substances 0.000 description 10
- 230000001360 synchronised effect Effects 0.000 description 10
- 239000000203 mixture Substances 0.000 description 7
- 230000005284 excitation Effects 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 238000012360 testing method Methods 0.000 description 5
- 230000001900 immune effect Effects 0.000 description 3
- 230000009870 specific binding Effects 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 239000012470 diluted sample Substances 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000010355 oscillation Effects 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 241000270722 Crocodylidae Species 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000027455 binding Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- LNNWVNGFPYWNQE-GMIGKAJZSA-N desomorphine Chemical compound C1C2=CC=C(O)C3=C2[C@]24CCN(C)[C@H]1[C@@H]2CCC[C@@H]4O3 LNNWVNGFPYWNQE-GMIGKAJZSA-N 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 239000012898 sample dilution Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000004148 unit process Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
Description
Claims (10)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710695530.6A CN109406498B (zh) | 2017-08-15 | 2017-08-15 | 一种免疫测定装置 |
PCT/CN2017/112145 WO2018095314A1 (zh) | 2016-11-22 | 2017-11-21 | 鉴定hd-hook效应样本和免疫测定的方法、***、试剂盒及装置 |
US16/462,968 US20190353664A1 (en) | 2016-11-22 | 2017-11-21 | Method, system, reagent kit, and device for determining hd-hook-effect sample and immunoassay |
EP17874359.7A EP3546937A4 (en) | 2016-11-22 | 2017-11-21 | METHOD, SYSTEM, REAGENT KIT AND SYSTEM FOR CHECKING A HIGH DOSE HOOK SAMPLE AND FOR IMMUNOASSAY |
JP2019547751A JP6980800B2 (ja) | 2016-11-22 | 2017-11-21 | Hd−hook効果サンプルと免疫測定を同定する方法、システム、キット及び装置 |
KR1020197014563A KR102220361B1 (ko) | 2016-11-22 | 2017-11-21 | Hd-hook 효과 시료 식별 및 면역 측정 방법, 시스템, 키트 및 장치 |
ZA2018/05983A ZA201805983B (en) | 2016-11-22 | 2018-09-06 | Method, system, reagent kit and system for verifying hd-hook effect sample |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710695530.6A CN109406498B (zh) | 2017-08-15 | 2017-08-15 | 一种免疫测定装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN109406498A CN109406498A (zh) | 2019-03-01 |
CN109406498B true CN109406498B (zh) | 2024-03-29 |
Family
ID=65454064
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710695530.6A Active CN109406498B (zh) | 2016-11-22 | 2017-08-15 | 一种免疫测定装置 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109406498B (zh) |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6210975B1 (en) * | 1990-10-30 | 2001-04-03 | Roche Diagnostics Gmbh | Process for determining a bindable analyte via immune precipitation and reagent therefor |
CN1880959A (zh) * | 2005-06-17 | 2006-12-20 | 上海透景生命科技有限公司 | 一种指示高剂量钩状效应的方法 |
CN101201353A (zh) * | 2006-12-14 | 2008-06-18 | 上海透景生命科技有限公司 | 一种扩展免疫检测可测量范围的方法及试剂盒 |
CN101387650A (zh) * | 2007-12-20 | 2009-03-18 | 北京科美生物技术有限公司 | 全自动板式发光仪及其发光检测方法 |
CN103399161A (zh) * | 2013-07-17 | 2013-11-20 | 深圳市新产业生物医学工程股份有限公司 | 一种便捷式全自动化学发光免疫分析***及其分析方法 |
CN105044332A (zh) * | 2015-06-04 | 2015-11-11 | 天津起跑线生物信息技术有限公司 | 一种监测免疫胶体金试验中hook效应的方法 |
CN105823880A (zh) * | 2016-03-21 | 2016-08-03 | 中国科学院理化技术研究所 | 一种利用钩状效应拓展检测范围的生物芯片及其检测方法 |
CN207147974U (zh) * | 2017-08-15 | 2018-03-27 | 博阳生物科技(上海)有限公司 | 一种免疫测定装置 |
-
2017
- 2017-08-15 CN CN201710695530.6A patent/CN109406498B/zh active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6210975B1 (en) * | 1990-10-30 | 2001-04-03 | Roche Diagnostics Gmbh | Process for determining a bindable analyte via immune precipitation and reagent therefor |
CN1880959A (zh) * | 2005-06-17 | 2006-12-20 | 上海透景生命科技有限公司 | 一种指示高剂量钩状效应的方法 |
CN101201353A (zh) * | 2006-12-14 | 2008-06-18 | 上海透景生命科技有限公司 | 一种扩展免疫检测可测量范围的方法及试剂盒 |
CN101387650A (zh) * | 2007-12-20 | 2009-03-18 | 北京科美生物技术有限公司 | 全自动板式发光仪及其发光检测方法 |
CN103399161A (zh) * | 2013-07-17 | 2013-11-20 | 深圳市新产业生物医学工程股份有限公司 | 一种便捷式全自动化学发光免疫分析***及其分析方法 |
CN105044332A (zh) * | 2015-06-04 | 2015-11-11 | 天津起跑线生物信息技术有限公司 | 一种监测免疫胶体金试验中hook效应的方法 |
CN105823880A (zh) * | 2016-03-21 | 2016-08-03 | 中国科学院理化技术研究所 | 一种利用钩状效应拓展检测范围的生物芯片及其检测方法 |
CN207147974U (zh) * | 2017-08-15 | 2018-03-27 | 博阳生物科技(上海)有限公司 | 一种免疫测定装置 |
Also Published As
Publication number | Publication date |
---|---|
CN109406498A (zh) | 2019-03-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN106872420B (zh) | 一种时间分辨荧光定量检测尿微量白蛋白的试剂盒及方法 | |
CN207147974U (zh) | 一种免疫测定装置 | |
KR102220361B1 (ko) | Hd-hook 효과 시료 식별 및 면역 측정 방법, 시스템, 키트 및 장치 | |
EP0198513B1 (en) | Analytical method and apparatus for determining fluorescence or phosphorescence | |
JP4712033B2 (ja) | 生体サンプルの複合自動分析装置、自動分析方法、及び反応キュベット | |
JP3535144B2 (ja) | 自動連続ランダムアクセス分析システムおよびその構成要素 | |
CN100473989C (zh) | 采用时间分辨荧光的基于膜的检测 | |
CN105403698A (zh) | 采用内部校正***的诊断性试验试剂盒 | |
US8927294B2 (en) | Bead reader | |
EP0521636A1 (en) | Method of assay of enzymatic activity and apparatus therefor | |
JP2003014769A (ja) | 自動分析機 | |
CN109470856A (zh) | 免疫测定方法、用于鉴定免疫测定的***和试剂盒 | |
JP2769245B2 (ja) | 検定結果を検証する方法及び自動連続ランダムアクセス分析システムを作動する方法 | |
CN102301238A (zh) | 自动分析装置 | |
JP2517102B2 (ja) | 免疫測定装置の発光光量検出方法 | |
CN109406498B (zh) | 一种免疫测定装置 | |
CN113533743A (zh) | 一种使用化学放光方法检测人类vegf-a浓度的生物分析方法 | |
CN102087215A (zh) | 荧光定量检测仪 | |
CN115389760B (zh) | 用于免疫分析试条的检测试剂 | |
CN112630454A (zh) | 一种全自动化学发光免疫分析仪 | |
JP3001994B2 (ja) | 自動分析装置 | |
RU2480772C1 (ru) | Способ одновременного детектирования тиротропина и общего тироксина в сухих пятнах крови | |
CN110470854A (zh) | 全自动免疫分析仪 | |
WO2023053586A1 (ja) | イムノクロマトグラフキット及び検査装置 | |
Yang et al. | Development of a quantifiable optical reader for lateral flow immunoassay |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB02 | Change of applicant information | ||
CB02 | Change of applicant information |
Address after: 201210 floor 3 and 5, building 1, No. 88, Cailun Road, free trade zone, Pudong New Area, Shanghai Applicant after: BEYOND DIAGNOSTICS (SHANGHAI) Co.,Ltd. Applicant after: Kemei Diagnostic Technology Co.,Ltd. Address before: 201210 Shanghai City, Pudong New Area Free Trade Zone No. 88 five floor East Cailun Road Applicant before: BEYOND DIAGNOSTICS (SHANGHAI) Co.,Ltd. Applicant before: BEIJING CHEMCLIN BIOTECH Co.,Ltd. |
|
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Practicing Zifu Inventor after: Liu Guidong Inventor after: Wu Dongyang Inventor after: Fang Quan Inventor after: Zhao Weiguo Inventor after: Liu Yuhui Inventor after: Li Lin Inventor before: Practicing Zifu Inventor before: Liu Guidong Inventor before: Wu Dongyang Inventor before: Fang Quan Inventor before: Zhao Weiguo Inventor before: Liu Yuhui Inventor before: Li Lin |
|
CB02 | Change of applicant information | ||
CB02 | Change of applicant information |
Address after: 200131 third and fifth floors, building 1, No. 88 Cailun Road, pilot Free Trade Zone, Pudong New Area, Shanghai Applicant after: Kemei Boyang diagnostic technology (Shanghai) Co.,Ltd. Applicant after: Kemei Diagnostic Technology Co.,Ltd. Address before: 201210 third and fifth floors, building 1, No. 88, Cailun Road, pilot Free Trade Zone, Pudong New Area, Shanghai Applicant before: BEYOND DIAGNOSTICS (SHANGHAI) Co.,Ltd. Applicant before: Kemei Diagnostic Technology Co.,Ltd. |
|
GR01 | Patent grant | ||
GR01 | Patent grant |