CN109364230A - A kind of Chinese medicine and preparation method thereof for treating chicken coccidiasis - Google Patents
A kind of Chinese medicine and preparation method thereof for treating chicken coccidiasis Download PDFInfo
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Abstract
The present invention relates to the field of Chinese medicines of poultry treatment, specially a kind of Chinese medicines and preparation method thereof for treating chicken coccidiasis.A kind of Chinese medicine for treating chicken coccidiasis, is prepared from the following raw materials in parts by weight: 10-20 parts of the coptis, 10-20 parts of the bark of ash, 10-20 parts of radix rehmanniae recen, 10-20 parts of Herba Euphorbiae Humifusae, 8-15 parts of the Chinese bulbul, 3-8 parts of alumen, 15-25 parts of sweet wormwood, 15-25 parts of kuh-seng, 8-15 parts of radix aucklandiae, 10-20 parts of Rhizoma Atractylodis Macrocephalae, 8-15 parts of Radix Glycyrrhizae, 8-20 parts of rhizoma zingiberis, 10-20 parts of Changshan, 8-15 parts in one's early teens.Above-mentioned Chinese medicine is put into Chinese medicine extracting tank, add water to cook, refluxing extraction twice, merge and filter after decocting liquid twice, be cooled to room temperature after filtrate concentration, obtain herb liquid.The effect of analgesic.Chinese medicine of the invention can effectively treat loss of appetite caused by chicken coccidiasis, and diarrhea, often band blood, anaemia are dehydrated excrement, the symptoms such as production performance decline.
Description
Technical field
The present invention relates to the field of Chinese medicines of poultry treatment, specially a kind of Chinese medicine for treating chicken coccidiasis and its preparation side
Method.
Background technique
Chicken coccidiasis is that a kind of parasitism caused in chicken intestinal epithelial cell is parasitized by a variety of coccidias of Eimeria
Property protozoosis.Eimeria species distribution is wide, harm is big, and type is different, parasitic site and pathogenic also variant, wherein tender Amy
Ear ball worm be it is pathogenic most strong, endanger the most serious one kind.
Chicken coccidiasis is to cause poultry husbandry, especially one of the principal disease of broiler chicken industry heavy economic losses, generally in 15-
Occur in 50 days chick groups, the death rate is up to 80% or so.Obtaining the chicken of chicken coccidiasis, growth and development all can under normal circumstances
It is hindered, feed conversion rate reduction, lay eggs reduction and carcase quality decline etc., or even will affect immune system, generate immune
Inhibit.
Mainly based on vaccine inoculation prevention and chemicals treatment, vaccine inoculation has centainly for the prevention and treatment of chicken coccidiasis at present
Preventive effect, but protecting effect is less desirable, chicken group or often outburst globidiosis, especially in white meat-type chickens group.Change
Learning drug mainly has toltrazuril, diclazuril, composite sulfamonomethoxine sodium, sulfaclozine sodium etc., long-time serviceization
Learning drug treatment makes coccidia generate drug resistance, causes chemotherapy effect undesirable.
Chinese herbal medicine not only can effectively press down worm of killing, moreover it is possible to which the immune function for enhancing chicken body promotes the growth and development of chicken, improves
Rate of body weight gain and production performance pay close attention to food in people in addition toxic side effect is small, the advantages that being not likely to produce drug resistance and medicament residue
Today of safety, Chinese herb prevention globidiosis have broader prospect.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicines and preparation method thereof for treating chicken coccidiasis.
To achieve the above object, the invention adopts a technical scheme as:
A kind of Chinese medicine for treating chicken coccidiasis, is prepared from the following raw materials in parts by weight: 10-20 parts of the coptis, bark of ash 10-20
Part, 10-20 parts of radix rehmanniae recen, 10-20 parts of Herba Euphorbiae Humifusae, 8-15 parts of the Chinese bulbul, 3-8 parts of alumen, 15-25 parts of sweet wormwood, kuh-seng 15-25
Part, 8-15 parts of radix aucklandiae, 10-20 parts of Rhizoma Atractylodis Macrocephalae, 8-15 parts of Radix Glycyrrhizae, 8-20 parts of rhizoma zingiberis, 10-20 parts of Changshan, 8-15 parts in one's early teens.
Preferably, it is prepared from the following raw materials in parts by weight: 15 parts of the coptis, 15 parts of the bark of ash, 15 parts of radix rehmanniae recen, Herba Euphorbiae Humifusae 15
Part, 10 parts of the Chinese bulbul, 5 parts of alumen, 20 parts of sweet wormwood, 20 parts of kuh-seng, 10 parts of radix aucklandiae, 15 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Radix Glycyrrhizae, 15 parts of rhizoma zingiberis,
15 parts of Changshan, 10 parts in one's early teens.
The preparation method of the Chinese medicine of the treatment chicken coccidiasis is to put into above-mentioned Chinese medicine in Chinese medicine extracting tank, adds decocting
Boil, refluxing extraction twice, merge and filter after decocting liquid twice, be cooled to room temperature after filtrate concentration, obtain herb liquid.
The refluxing extraction twice the specific steps are boil rear refluxing extraction 2.5 hours, after boiling for the second time for the first time
Refluxing extraction 1.5 hours, boiling conditions were lower 100 DEG C of normal pressure, and first time amount of water is 10 times of total quality of medicinal material, were added for the second time
Water is 8 times of total quality of medicinal material.
Temperature is 60-70 DEG C in the filtrate concentration process, and vacuum degree is -0.06MPa, and concentrate relative density is
1.10-1.20。
The preparation method of refluxing extraction of the invention can be such that the effective component of Chinese medicine sufficiently discharges, and enhance curative effect of medication.
Different drugs is mutually compatible, and wherein effective component is not identical, interacts between effective component also not identical, it should
The therapeutic effect of Chinese medicine composition is considered on the whole.Meanwhile the dosage of each drug is different, the difference of drug dose can be to entirety
Drug effect has a great impact.Chinese medicine flavour of a drug plus-minus, dose increase and decrease all can to its function generate Different Effects, can change its monarch,
The compatibility relationship of minister causes its major function then far apart different to change site of action and pharmaceutical properties.
Chinese medicine of the present invention by the coptis, the bark of ash, radix rehmanniae recen, Herba Euphorbiae Humifusae, the Chinese bulbul, alumen, sweet wormwood, kuh-seng, radix aucklandiae, Rhizoma Atractylodis Macrocephalae,
Radix Glycyrrhizae, Changshan, forms rhizoma zingiberis in one's early teens.Chicken coccidiasis mainly encroaches on enteron aisle, shows as small intestine intestinal wall and thickens, mucous membrane jaundice, has
Small mottled bleeding, caecum enlargement, content have a blood clot, form intestines bolt, and illness chicken manure is thin, band blood, cockscomb is pale,
Anaemia etc..This disease principle of reatment are as follows: it is clearing heat and detoxicating, it removes heat from the blood and relieve diarrhea, invigorating spleen to remove dampness, desinsection analgesic.The Chinese bulbul, the coptis, the bark of ash, life
Glutinous rehmannia, Herba Euphorbiae Humifusae share have effects that it is clearing heat and detoxicating, remove heat from the blood and relieve diarrhea；Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, rhizoma zingiberis can invigorating spleen to remove dampness；Changshan, careless beans
It is cool that there is the effect of eliminating dampness promoting the circulation of qi；Alumen, sweet wormwood, kuh-seng, radix aucklandiae share can desinsection analgesic, all medicines share can be very good to solve
This disease.
Beneficial effects of the present invention:
Chinese medicine of the invention is by the scientific compatibility of monarch, the effect of temperature compensation lung qi, invigorating the spleen to clear away damp pathogen, anti-inflammatory analgetic.
Chinese medicine of the invention can effectively treat diseased chicken loss of appetite, and diarrhea, often band blood, anaemia are dehydrated, productivity excrement
The symptoms such as energy decline.
Chinese medicine of the invention not only can effectively press down worm of killing, moreover it is possible to which the immune function for enhancing chicken body promotes the growth of chicken to send out
It educates, improves rate of body weight gain and production performance, toxic side effect is small, the advantages that being not likely to produce drug resistance and medicament residue.
Chinese medicine of the present invention reduces the use of antibiotic, carries out green nonreactive cultivation, ensures the safe, strong of poultry product
Health.
Specific embodiment
Embodiment 1
15 parts of the coptis, 15 parts of the bark of ash, 15 parts of radix rehmanniae recen, 15 parts of Herba Euphorbiae Humifusae, 10 parts of the Chinese bulbul, 5 parts of alumen, 20 parts of sweet wormwood,
20 parts of kuh-seng, 10 parts of radix aucklandiae, 15 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Radix Glycyrrhizae, 15 parts of rhizoma zingiberis, 15 parts of Changshan, 10 parts in one's early teens, above-mentioned Chinese medicine is thrown
Enter in Chinese medicine extracting tank, add water to cook, refluxing extraction twice, merge and filter after decocting liquid twice, be cooled to room temperature after filtrate concentration,
Obtain herb liquid.Refluxing extraction twice the specific steps are boil rear refluxing extraction 2.5 hours, after boiling for the second time for the first time
Refluxing extraction 1.5 hours, boiling conditions were lower 100 DEG C of normal pressure, and first time amount of water is 10 times of total quality of medicinal material, were added for the second time
Water is 8 times of total quality of medicinal material.Temperature is 70 DEG C in filtrate concentration process, and vacuum degree is -0.06MPa, and concentrate is relatively close
Degree is 1.15.
Embodiment 2
10 parts of the coptis, 10 parts of the bark of ash, 10 parts of radix rehmanniae recen, 10 parts of Herba Euphorbiae Humifusae, 8 parts of the Chinese bulbul, 3 parts of alumen, 15 parts of sweet wormwood, hardship
Join 15 parts, 8 parts of radix aucklandiae, 10 parts of Rhizoma Atractylodis Macrocephalae, 8 parts of Radix Glycyrrhizae, 8 parts of rhizoma zingiberis, 10 parts of Changshan, 8 parts in one's early teens, above-mentioned Chinese medicine is thrown in order
Enter in Chinese medicine extracting tank, add water to cook, refluxing extraction twice, merge and filter after decocting liquid twice, be cooled to room temperature after filtrate concentration,
Obtain herb liquid.Refluxing extraction twice the specific steps are boil rear refluxing extraction 2.5 hours, after boiling for the second time for the first time
Refluxing extraction 1.5 hours, boiling conditions were lower 100 DEG C of normal pressure, and first time amount of water is 10 times of total quality of medicinal material, were added for the second time
Water is 8 times of total quality of medicinal material.Temperature is 60 DEG C in filtrate concentration process, and vacuum degree is -0.06MPa, and concentrate is relatively close
Degree is 1.10.
Embodiment 3
20 parts of the coptis, 20 parts of the bark of ash, 20 parts of radix rehmanniae recen, 20 parts of Herba Euphorbiae Humifusae, 15 parts of the Chinese bulbul, 8 parts of alumen, 25 parts of sweet wormwood,
25 parts of kuh-seng, 15 parts of radix aucklandiae, 20 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of Radix Glycyrrhizae, 20 parts of rhizoma zingiberis, 20 parts of Changshan, 15 parts in one's early teens, above-mentioned Chinese medicine is pressed
In sequence investment Chinese medicine extracting tank, add water to cook, refluxing extraction twice, merge and filter after decocting liquid twice, it is cooling after filtrate concentration
To room temperature, herb liquid is obtained.Refluxing extraction twice the specific steps are, boil rear refluxing extraction for the first time 2.5 hours, second
Boiling rear refluxing extraction 1.5 hours, boiling conditions are lower 100 DEG C of normal pressure, and first time amount of water is 10 times of total quality of medicinal material, the
Secondary amount of water is 8 times of total quality of medicinal material.Temperature is 70 DEG C in filtrate concentration process, and vacuum degree is -0.06MPa, concentrate
Relative density is 1.20.
Clinical test
Specific dosage are as follows: every 250ml herb liquid feeds diseased chicken, once a day, feeding volume after adding 200Kg-300Kg water to dilute
For every diseased chicken 0.2-0.3mL Chinese medicine stoste, concentrating the drink medicine time is 3-4 hours, continuous use 3-5 days.
3000 symptom diseased chickens are chosen to be grouped.Test medicine is the Chinese medicine of Examples 1 and 2 preparation, specific usage
Dosage be 250ml herb liquid be added 250kg water dilution, once a day, concentrate drink the medicine time be 4 hours, feeding volume be every at
Chicken 0.2mL Chinese medicine stoste, continuous use 4 days.Control group is the solution of diclazuril that content is 10%, and dosage is 166mL medical fluid
It is diluted with 80kg water, is even fed 4 days.Test result is shown in Table 1.
The death rate: after medication, there is death in clinic, and the percentage that death toll accounts for this group of test chicken sum is the death rate.
Cure rate: after medication, clinical symptoms are completely disappeared, and curing number and accounting for the percentage of this group of test chicken sum is to cure
Rate.
Inefficiency: after medication, clinical symptoms have no mitigation, in addition occur deteriorating or death be it is invalid, invalid number accounts for the group
The percentage of test chicken sum is inefficiency.
It is efficient: after medication, clinical symptom relief but not completely disappear, search for food, drink water and the physical signs such as spirit become
In normally be it is effective, the percentage that significant figure accounts for this group of test chicken sum is as efficient.
Table 1
| Group | Quantity/only | The death rate | Cure rate | Inefficiency | It is efficient | |
| 1 | Solution of diclazuril group | 1000 | 8% | 81% | 10% | 90% |
| 2 | Example 1 group | 1000 | 4% | 88% | 7% | 93% |
| 3 | 2 groups of embodiment | 1000 | 5% | 85% | 9% | 91% |
As seen from the results in Table 1, it is molten to be apparently higher than diclazuril in terms of cure rate and effective percentage for Chinese herbs group of the present invention
Liquid group, while solution of diclazuril belongs to western medicine antibiotics, excessive use influences the quality of chicken, and drug resistance easy to form,
Chinese medicine of the invention can achieve effect identical with existing antibiotic, and reduce the use of antibiotic, ensure poultry production
Product it is safe and healthy.Chinese medicine of the invention not only can effectively press down worm of killing, moreover it is possible to enhance by the scientific compatibility of monarch
The immune function of chicken body promotes the growth and development of chicken, improves rate of body weight gain and production performance.
Claims (5)
1. a kind of Chinese medicine for treating chicken coccidiasis, which is characterized in that be prepared from the following raw materials in parts by weight: 10-20 parts of the coptis,
10-20 parts of the bark of ash, 10-20 parts of radix rehmanniae recen, 10-20 parts of Herba Euphorbiae Humifusae, 8-15 parts of the Chinese bulbul, 3-8 parts of alumen, 15-25 parts of sweet wormwood, hardship
Join 15-25 parts, 8-15 parts of radix aucklandiae, 10-20 parts of Rhizoma Atractylodis Macrocephalae, 8-15 parts of Radix Glycyrrhizae, 8-20 parts of rhizoma zingiberis, 10-20 parts of Changshan, in one's early teens 8-15
Part.
2. the Chinese medicine for the treatment of chicken coccidiasis according to claim 1, which is characterized in that by the raw material system of following parts by weight
At: 15 parts of the coptis, 15 parts of the bark of ash, 15 parts of radix rehmanniae recen, 15 parts of Herba Euphorbiae Humifusae, 10 parts of the Chinese bulbul, 5 parts of alumen, 20 parts of sweet wormwood, kuh-seng 20
Part, 10 parts of radix aucklandiae, 15 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Radix Glycyrrhizae, 15 parts of rhizoma zingiberis, 15 parts of Changshan, 10 parts in one's early teens.
3. a kind of preparation method of the Chinese medicine for the treatment of chicken coccidiasis of any of claims 1 or 2, it is characterised in that: will among the above
Medicine is put into Chinese medicine extracting tank, add water to cook, refluxing extraction twice, merge and filter after decocting liquid twice, be cooled to after filtrate concentration
Room temperature obtains herb liquid.
4. the preparation method of the Chinese medicine for the treatment of chicken coccidiasis according to claim 3, it is characterised in that: the refluxing extraction two
It is secondary that the specific steps are boil rear refluxing extraction 2.5 hours for the first time, boil rear refluxing extraction for the second time 1.5 hours, boil item
Part is lower 100 DEG C of normal pressure, and first time amount of water is 10 times of total quality of medicinal material, and second of amount of water is 8 times of total quality of medicinal material.
5. the Chinese medicine for the treatment of chicken coccidiasis according to claim 3, which is characterized in that temperature in the filtrate concentration process
It is 60-70 DEG C, vacuum degree is -0.06MPa, and concentrate relative density is 1.10-1.20.
Priority Applications (1)
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078522A (en) * | 2009-11-27 | 2011-06-01 | 天津瑞普生物技术股份有限公司 | Chinese medicine composition for treating enterovirus syndrome in chicken |
| CN103784771A (en) * | 2011-06-29 | 2014-05-14 | 纽素乐必佳（天津）药业集团有限公司 | Traditional Chinese medicine composition has functions of anticoccidia, haemostasis and blood enriching, and antibiosis and antiphlogosis, and preparation method thereof |
| CN104208238A (en) * | 2013-09-29 | 2014-12-17 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for treating chicken coccidiosis and preparation method thereof |
| CN107952012A (en) * | 2017-12-29 | 2018-04-24 | 格润高科（天津）生物技术有限公司 | A kind of Chinese medicine composition for preventing global-worm illness and preparation method thereof |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078522A (en) * | 2009-11-27 | 2011-06-01 | 天津瑞普生物技术股份有限公司 | Chinese medicine composition for treating enterovirus syndrome in chicken |
| CN103784771A (en) * | 2011-06-29 | 2014-05-14 | 纽素乐必佳（天津）药业集团有限公司 | Traditional Chinese medicine composition has functions of anticoccidia, haemostasis and blood enriching, and antibiosis and antiphlogosis, and preparation method thereof |
| CN104208238A (en) * | 2013-09-29 | 2014-12-17 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for treating chicken coccidiosis and preparation method thereof |
| CN107952012A (en) * | 2017-12-29 | 2018-04-24 | 格润高科（天津）生物技术有限公司 | A kind of Chinese medicine composition for preventing global-worm illness and preparation method thereof |
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Application publication date: 20190222 |